Telstar LyoQuest Troubleshooting guide

USER & SERVICE MANUAL
MANUAL DE USUARIO Y MANTENIMIENTO
Laboratory Freeze Dryers
Liofilizadores de laboratorio

IM-LYOQUEST-EN-SP-1016a.doc 2 / 80

IM-LYOQUEST-EN-SP-1016a.doc 3 / 80
INDEX / ÍNDICE
1. GENERAL DATA ..................................................................................................................................... 6
2. DETAILS OF THE FREEZE-DRYER ............................................................................................................. 7
2.1. Aim of this manual ................................................................................................................................................... 7
2.2. Application ............................................................................................................................................................... 7
2.3. Requirements ........................................................................................................................................................... 7
2.4. Description ............................................................................................................................................................... 7
3. TECHNICAL CHARACTERISTICS ............................................................................................................... 9
4. TRANSPORT AND PACKING ................................................................................................................. 10
5. BEFORE START- P ............................................................................................................................... 10
5.1. Placing on site ........................................................................................................................................................ 10
5.2. Electrical connection .............................................................................................................................................. 10
5.3. acuum pump ........................................................................................................................................................ 10
5.4. Refrigerating unit ................................................................................................................................................... 11
6. RECOMMENDATIONS .......................................................................................................................... 11
6.1. Ice condenser ......................................................................................................................................................... 11
6.2. Greasing ................................................................................................................................................................. 11
6.3. Long stoppage ........................................................................................................................................................ 11
7. WORKING PRINCIPLE .......................................................................................................................... 12
7.1. Freeze ..................................................................................................................................................................... 12
7.2. Lyophilization ......................................................................................................................................................... 12
7.2.1. In manifold .......................................................................................................................................................... 12
7.2.2. In chamber .......................................................................................................................................................... 13
7.2.3. End of the process ............................................................................................................................................... 14
7.3. Lyophilization modes ............................................................................................................................................. 14
7.4. Selectable processes .............................................................................................................................................. 14
8. OPTIONAL ACCESORIES (COMPILATION AT THE END OF THE MAN AL) ................................................ 15
8.1. Chambers ............................................................................................................................................................... 15
8.2. Manifolds ............................................................................................................................................................... 16
8.3. Flasks condensations collector (Drip tray) ............................................................................................................. 16
8.4. Lyoquestlogger software ....................................................................................................................................... 17
9. INSTR CTIONS FOR SE ...................................................................................................................... 18
9.1. Start up ................................................................................................................................................................... 18
9.2. Semiautomatic mode ............................................................................................................................................. 19
9.3. Automatic mode .................................................................................................................................................... 19
9.4. Defrosting mode .................................................................................................................................................... 20
9.5. Menu ...................................................................................................................................................................... 20
9.6. Hours counter vacuum pump ................................................................................................................................ 21
9.7. Stop of the freeze-dryer ......................................................................................................................................... 21
9.8. No Plus version ...................................................................................................................................................... 22
10. RECIPES .............................................................................................................................................. 23
11. ALARMS .............................................................................................................................................. 23
12. MAINTENANCE PLAN .......................................................................................................................... 25
12.1. acuum unit maintenance ..................................................................................................................................... 25
12.2. Refrigerating system maintenance ........................................................................................................................ 27
12.3. Surface cleaning and disinfection .......................................................................................................................... 27
12.4. Maintenance table ................................................................................................................................................. 27
13. TRO BLESHOOTING ............................................................................................................................ 28
13.1. acuum unit ........................................................................................................................................................... 28
13.2. Refrigerating unit ................................................................................................................................................... 28
13.3. Freeze-dryer kit ...................................................................................................................................................... 29

IM-LYOQUEST-EN-SP-1016a.doc 4 / 80
1. DATOS GENERALES ............................................................................................................................. 31
2. DATOS DEL LIOFILIZADOR .................................................................................................................... 32
2.1. Objetivo del manual ............................................................................................................................................... 32
2.2. Aplicación ............................................................................................................................................................... 32
2.3. Requerimientos ...................................................................................................................................................... 32
2.4. Descripción ............................................................................................................................................................. 32
3. CARACTERÍSTICAS TÉCNICAS ............................................................................................................... 34
4. TRANSPORTE Y EMBALAJE .................................................................................................................. 35
5. ANTES DE LA P ESTA EN MARCHA ...................................................................................................... 35
5.1. Emplazamiento del equipo .................................................................................................................................... 35
5.2. Conexión eléctrica .................................................................................................................................................. 35
5.3. Bomba de vacío ...................................................................................................................................................... 35
5.4. Grupo frigorífico ..................................................................................................................................................... 36
6. RECOMENDACIONES ........................................................................................................................... 36
6.1. Condensador de hielo ............................................................................................................................................ 36
6.2. Engrase ................................................................................................................................................................... 36
6.3. Paro prolongado .................................................................................................................................................... 36
7. PRINCIPIO DE F NCIONAMIENTO ........................................................................................................ 37
7.1. Congelación ............................................................................................................................................................ 37
7.2. Liofilización............................................................................................................................................................. 37
7.2.1. En manifold ......................................................................................................................................................... 37
7.2.2. En cámara ........................................................................................................................................................... 38
7.2.3. Finalización del proceso ...................................................................................................................................... 39
7.3. Modos de liofilización ............................................................................................................................................ 39
7.4. Procesos seleccionables ......................................................................................................................................... 39
8. ACCESORIOS OPCIONALES (RECOPILATORIO AL FINAL DEL MAN AL) ................................................... 40
8.1. Cámaras ................................................................................................................................................................. 40
8.2. Manifolds ............................................................................................................................................................... 41
8.3. Recogedor de las condensaciones de los frascos (Drip tray) ................................................................................. 41
8.4. Lyoquestlogger software ....................................................................................................................................... 42
9. INSTR CCIONES DE SO ..................................................................................................................... 43
9.1. Puesta en marcha .................................................................................................................................................. 43
9.2. Modo de funcionamiento semiautomático ........................................................................................................... 44
9.3. Modo de funcionamiento automático ................................................................................................................... 44
9.4. Modo de funcionamiento descarche ..................................................................................................................... 45
9.5. Menú ...................................................................................................................................................................... 45
9.6. Contador horas bomba de vacío ............................................................................................................................ 46
9.7. Parada del liofilizador ............................................................................................................................................ 46
9.8. ersión No Plus ...................................................................................................................................................... 47
10. RECETAS ............................................................................................................................................. 48
11. ALARMAS ........................................................................................................................................... 48
12. PLAN DE MANTENIMIENTO ................................................................................................................. 50
12.1. Mantenimiento del grupo de vacío ....................................................................................................................... 50
12.2. Mantenimiento del grupo frigorífico ..................................................................................................................... 52
12.3. Limpieza y desinfección superficial ........................................................................................................................ 52
12.4. Tabla de mantenimiento ........................................................................................................................................ 52
13. ANOMALÍAS DE F NCIONAMIENTO .................................................................................................... 53
13.1. Bomba de vacío ...................................................................................................................................................... 53
13.2. Grupo frigorífico ..................................................................................................................................................... 54
13.3. Conjunto liofilizador ............................................................................................................................................... 54

IM-LYOQUEST-EN-SP-1016a.doc 5 / 80
14. ANNEXES /ANEXOS ............................................................................................................................. 55
14.1. Equipment spare part codes / Códigos de los recambios de la instalación ........................................................... 55
14.2. Examples of recipes / Ejemplos de recetas ............................................................................................................ 56
14.3. Maintenance records / Histórico de mantenimiento ........................................................................................... 58
14.4. Decontamination declaration / Declaración de descontaminación ...................................................................... 60
14.5. Refrigerating system P&ID / P&ID Sistema de refrigeración (Lyoquest -55) ......................................................... 61
14.6. Refrigerating system P&ID / P&ID Sistema de refrigeración (Lyoquest -85) ......................................................... 62
14.7. acuum system P&ID / P&ID Sistema de vacío ..................................................................................................... 63
14.8. Electric diagrams / Esquemas eléctricos (Lyoquest -55) ........................................................................................ 64
14.9. Electric diagrams key / Leyenda esquemas eléctricos (Lyoquest -55) ................................................................... 69
14.10. Electric diagrams / Esquemas eléctricos (Lyoquest -85) .................................................................................... 70
14.11. Electric diagrams key / Leyenda esquemas eléctricos (Lyoquest -85) ............................................................... 75
14.12. Warranty certificate / Certificado de garantía ................................................................................................... 76
14.13. Declaration of conformity / Declaración de conformidad ................................................................................. 77
14.14. Accessories configuration / Configuraciones de accesorios ............................................................................... 78
14.15. LyoQuest standard codification / Codificación estándar LyoQuest ................................................................... 79