5Pascal LIOSMART 100 User manual

User Manual
January, 2020
FREEZE DRYER
LIOSMART 100

WARRANTY
Cinquepascal S.r.l guaranties that the product
delivered has been thoroughly tested to ensure that it
meets its published specifications. The warranty is
valid only if the product has been installed and used
in accordance to the instructions supplied.
Cinquepascal S.r.l shall in no event be liable for
incidental or consequential damages, including
without limitations, lost profits, loss of income, loss of
business opportunities, loss of use, and other related
exposures, caused by incorrect use of product.
Warranty is valid for 13 months from date of shipping
and includes spare parts and labor.
Type:
LIOSMART 100
Serial number:
19116384
Date of shipping:
Signature/Stamp:
Manufacturer:
Cinquepascal S.r.l
Via Carpaccio, 35
Trezzano Sul Naviglio
20090 (MI) Italia
Tel: [phone]
Fax: [phone]
E-mail [email protected]t
Web: www.5pascal.it
Thank you for your trust and for buying this device.
We hope it will successfully serve the purpose for
many years.
CAREFULLY READ THESE INSTRUCTIONS
BEFORE USING THE DEVICE!

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CONTENT
1.0 WARNINGS AND SAFETY PRECAUTIONS ...................................................................................................... 4
2.0 INTRODUCTIONS .......................................................................................................................................... 5
3.0 TECHNICAL DATA ......................................................................................................................................... 6
4.0 USE PURPOSE AND SAFETY ELEMENTS ..................................................................................................... 13
5.0 INSTRUCTION FOR USE .............................................................................................................................. 14
5.1 Vacuum pump ....................................................................................................................................... 14
5.2 Control panel ......................................................................................................................................... 15
5.3 Display ................................................................................................................................................... 16
5.4 Basic setup ............................................................................................................................................. 16
5.5 Program selection and Start .................................................................................................................. 17
6.0 SETTINGS ................................................................................................................................................... 19
6.1 Parameter settings – Manual Program ................................................................................................. 19
6.2 Parameter settings – Automatic Program ............................................................................................. 23
7.0 SPECIAL SETUP ........................................................................................................................................... 25
7.1 Special Settings – Time and Date .......................................................................................................... 25
7.2 Corrections setup .................................................................................................................................. 26
7.3 Corrections setup scheme ..................................................................................................................... 27
7.4 Special Setup – User Passwords ............................................................................................................ 30
8.0 SERVICE AND MAINTENANCE .................................................................................................................... 32
9.0 REQUIRED SPACE AND CONNECTIONS ...................................................................................................... 33
10.0 DISMANTLING AND DISPOSAL ................................................................................................................. 34
11. ATTACHMENTS .......................................................................................................................................... 35
11.1 CE declaration of conformity ............................................................................................................... 35
11.2 Electro diagram ................................................................................................................................... 35

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1.0 WARNINGS AND
SAFETY PRECAUTIONS
READ ALL INSTRUCTIONS BEFORE USE!
Reduce the possibility of injury and failure!
WARNING
Before you
perform
any kind of maintenance, disconnect all electrical power
to the unit! DO NOT operate this unite without a properly grounded,
properly polarized power cord! DO NOT connect this unite to a non-polarized
outlet!
DANGER
Appliance must not be installed in a room where the possibility of explosive
atmosphere is present!
DANGER OF BREAK DOWN
Service is only allowed to authorized personnel!
WARNING
Never use with toxic, corrosive, flammable or organic materials unless
special precautions are in place to prevent injury to personnel or damage to
equipment!
WARNING
Never operate the appliance with the housing removed!
DANGER OF BREAK DOWN
Close the door tightly before start! Do not try to open the door during the
cycle!
DANGER OF BURNS
Use safety gloves when operating with high / low temperatures!

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2.0 INTRODUCTIONS
Appliance description
Controller
This unit is equipped with microprocessor controller which is specially designed for automatization
of freeze drying cycles. Controller enables 50 different programs. Each of these 50 programs has
ability to set 50 different cycle steps.
Calibration, validation
The basic calibration is performed by the manufacturer. If ordered the calibration report is
delivered with the unit. Calibration, validation can also be done by the user because the appliance
has a special sub-program that allows easy settings and adjustments for temperature probes
without mechanical intervention on the device.

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3.0 TECHNICAL DATA
LIOSMART 100
Exterior dimensions (W x D x H)
1400 X 2178 x 1920 mm
Chamber dimensions (W x D x H) 750 x 1400 x 1000 mm
Ice condenser capacity 100 kg
Condenser In chamber
Ice condenser temperature
-
50°C
Ice condenser defrost
Reversible refrigeration system
Number of shelves 10
Shelve size 1240 x 600 mm
Shelve surface 10 x 0.74m2 = 7.4 m2
Shelve spacing
50 mm
Shelve Temperature range
-
40 …+ 70 °C
Temperature stability ±0,1 °C
Cooling Water cooled compressor system – condenser
Water cooled compressor system - shelves
Heating electrical
Doors Fully transparent single-handed closing
Power supply 3x400 V 50 Hz 57A (24 kW)
Communication RS-232 / USB
Temperature probe
PT
-
100
–
shelve temperature
PT-100 – condenser temperature
PT-100 Material
Vacuum probe
1 x Pirani vacuum on pump
1 x Pirani vacuum chamber
Vacuum pump Edwards EDS 200
Compressed air min 4 bar
Dry and oil free
Consumption negligible
Condenser drain Drain function to be manually activated on the
controller (Available only when program is Stopped)
Water supply
Cooling water
-
min 2 bar
- max temperature 25°C
Trolley 1 for shelves removal at maintenance
Tray 20 trays 600x600x30 mm

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Dimensional drawing:

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Dimensional drawing - shelves view:

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Connections:

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Shelves removal at maintenance:
1. Switch off device
2. Remove trays (use rod for tray removal)
3. Close all 4 ball valves at shelves connections
4. Disconnect flexible tubes (tri-clamp TC 50.5 connections)
5. Connect trolley to chamber (use two trolley safety bolts)
6. Deblock shelves
7. Carefully move shelves on trolley
8. Secure shelves with two shelve safety bolts
9. Disconnect trolley (remove two trolley safety bolts)
10. Carefully move trolley with shelves from chamber
Tray
Rod for tray removal

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Flexible tube
Shelves lock mechanism
Ball valve
Ball valve Ball valve
Ball valve
Flexible tube
Tri-clamp
Tri-clamp

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Trolley
Trolley
safety bolt
Shelves
safety bolt

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4.0 USE PURPOSE AND
SAFETY ELEMENTS
This freeze dryer is designed and build for many pilot and research or even small production
purposes.
Given the wide scope of specification, appliance is useful in many areas as, pharmacy, food
industry, biotechnology, …
It is not allowed to heat-up any material which could form explosive atmosphere.
Do not store any fluids on top of the housing!
The appliance may only be used in rooms where the possibility of explosive atmosphere is not
present!
Operating the unite with open doors can cause different errors or even break down.
Microprocessor controller has a special safety system which turns heaters off if temperature rises
for more than 5 °C above set temperature.
In case of an error on this system, a mechanical over temperature shut-off will disable heating. If
this happens the cause must be found and the over temperature shut-off must be manually reset.
The over temperature shut-off device is located behind the rear plate of the housing and is
manually reset by pressing the spring next to the thermostat setting shaft.
The appliance may only be used by trained personnel with enough practical experience regarding
heating, cooling and conditioning.
Each user is responsible for correct and safe use.
The device does not cause noise greater than 75 dB (excluding vacuum pump).
When indicating error, press "START/STOP" and switch the main switch in the off position
immediately. Contact service

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5.0 INSTRUCTION
FOR USE
Transport is usually carried in the original packaging. In case that the appliance has to be replaced, it
must be manually placed on a transport palette and only then lifted and transported with a vehicle.
Installation must be done in a dry, well ventilated room. Be sure that the chamber seal is always
clean and in superb condition!
Maintain top level condition of the vacuum pump.
5.1 Vacuum pump
Vacuum pump is one of the most important parts of every freeze dryer. Follow the original
manufacturer user and maintenance plan for vacuum pump.
ATTENTION:
Safety gloves use is a must when working with high/low temperatures!

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5.2 Control panel
Manual cycle
Automatic cycle
Cycle ended
Error
Settings ON
Printer ON (Printer error if
light flashes)
Confirmation
Start program
Stop program
Parameter selection
Value increase/decrease
Main menu
Nun pad
- F1 program copy confirmation button
- F2
- P Pump
- Measured value
- Cooling / Heating
- Working hours
- Program INFO
- Gas inlet – Vacuum break
Clear
Exit form menu

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* An operation is currently running if a function on the screen is colored in yellow.
 Example: Gas inlet is ON
5.3 Display
5.4 Basic setup
Step 1: Check condenser is clean and condensate removed
Step 2: Check power supply 3 x 400 V ±10%; 50Hz
Step 3: Place the material in chamber Close the chamber door.
Step 4: Put the main switch in position 1
Step 5: Select the preset program and press "START"
Step 7: From this moment on the device runs completely automatically
Step 8: Press "STOP" to stop the device (last step is always endless to keep the
condenser cold and system in vacuum)
Step 9: Press “Gas inlet – Vacuum brake” to be able to open the door and remove the
material
Step 10: Start manual program “program 0” and trigger condenser defrost, condenser
defrost will automatically stop after 10 minutes! (condenser defrost is not necessary also
you can leave the door open and wait overnight to melt the condenser naturally)
Tsh … current shelf temperature
P … current/ set pressure in chamber
Tm …temperature on material probe
Tc … current condenser temperature
Step Nr.:1: duration (10 minutes)
Tsh … current/set shelf temperature
P … current/ set pressure in chamber
Tm … temperature on material probe
Tc… current condenser temperature

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5.5 Program selection and Start
Turn on the main switch
Display:
T
sh = 15.6°C …current shelve temperature
Tc
= 19°C …current condenser temperature
P = 1015.0mb …current vacuum / pressure in chamber
Pp = 1015.0mb … current vacuum / pressure in vacuum pump
Tm =
13.1°C …Current temperature on material probe
Press to enter main menu
Display:
Press a number on a keyboard to enter in the selected sub-menu

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Press
1
To choose between programs press on the number (below display)
or use and press .
In the process
Meaning:
STEP Nr: 1: 10:00 First step in the process. Time set to 10 minutes [when temperature
reaches the tolerance area and parameter Tsh/Tm in in set limit the
time count down starts. See special settings]
Tsh=
26.0°C / -20.0°C Current shelve temperature is 26.0°C, set temp. -20.0°C
P= 1015.0mb / 1000.0mb Current chamber pressure is 1015.0 mbar set pressure is 1000 mbar
Tm
= 26.8°C Current temperature on material
T
c = 19.0°C Current condenser temperature
*Vacuum value from Pirani vacuum gauge. All values above 10 mb are treated as atmospheric
pressure. Only values below 10 mbar can be considered as correct measured value!
WARNING:
This kind of display indicates automatic running of selected program.

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6.0 SETTINGS
Press to enter main menu
Display:
If you press the number next to the written description you enter the described sub menu.
Press
To move between parameters press , to set value press .
ATTENTION:
If you press 2 – MANUAL manual program starts immediately! Parameters for manual
program can be set while
in operation
!
3
4
5
6
7
1
2
6.1
Parame
ter

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1. Select program
 Select desired program to set settings. Program 0 is reserved for manual
program
2. Program name
 Enter program name (the selected program can be named). Use numpad to
enter letters and numbers
3. Shelve temperature
 Set desired shelve temperature (temperature range is limited by machine
capacity).
Heating and cooling with closed loop thermal fluid.
4. Vacuum
 Set desired vacuum/pressure in chamber. On display you can see an available
vacuum range in mbar.
5. Condenser working mode:
- OFF
- Cooling: should only be used for shelf conditioning and not for material freezing
- Defrosting: when defrosting condensate must be drained from chamber
6. Cooling / Heating speed
 You can set temperature change rate of the shelve (°C/min)
(1°C/h…..250°C/h)
(system limits apply!)
7. Recording period
 Recording interval can be set from 1 in 200 minutes or switched off
ATTENTION:
If you set value lower than 1 minute recording is set to OFF!
ATTENTION:
If you set value 0.0010 mb, vacuum line towards vacuum pomp is constantly open!