Asus ROG STRIX B650E-E GAMING WIFI User manual

Motherboard
ROG STRIX
B650E-E GAMING
WIFI

ii
E20246
First Edition
July 2022
Copyright © 2022 ASUSTeK COMPUTER INC. All Rights Reserved.
No part of this manual, including the products and software described in it, may be reproduced,
transmitted, transcribed, stored in a retrieval system, or translated into any language in any form or by
any means, except documentation kept by the purchaser for backup purposes, without the express
written permission of ASUSTeK COMPUTER INC. (“ASUS”).
Product warranty or service will not be extended if: (1) the product is repaired, modified or altered, unless
such repair, modification of alteration is authorized in writing by ASUS; or (2) the serial number of the
product is defaced or missing.
ASUS PROVIDES THIS MANUAL “AS IS” WITHOUT WARRANTY OF ANY KIND, EITHER EXPRESS
OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE IMPLIED WARRANTIES OR CONDITIONS OF
MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. IN NO EVENT SHALL ASUS, ITS
DIRECTORS, OFFICERS, EMPLOYEES OR AGENTS BE LIABLE FOR ANY INDIRECT, SPECIAL,
INCIDENTAL, OR CONSEQUENTIAL DAMAGES (INCLUDING DAMAGES FOR LOSS OF PROFITS,
LOSS OF BUSINESS, LOSS OF USE OR DATA, INTERRUPTION OF BUSINESS AND THE LIKE),
EVEN IF ASUS HAS BEEN ADVISED OF THE POSSIBILITY OF SUCH DAMAGES ARISING FROM
ANY DEFECT OR ERROR IN THIS MANUAL OR PRODUCT.
SPECIFICATIONS AND INFORMATION CONTAINED IN THIS MANUAL ARE FURNISHED FOR
INFORMATIONAL USE ONLY, AND ARE SUBJECT TO CHANGE AT ANY TIME WITHOUT NOTICE,
AND SHOULD NOT BE CONSTRUED AS A COMMITMENT BY ASUS. ASUS ASSUMES NO
RESPONSIBILITY OR LIABILITY FOR ANY ERRORS OR INACCURACIES THAT MAY APPEAR IN
THIS MANUAL, INCLUDING THE PRODUCTS AND SOFTWARE DESCRIBED IN IT.
Products and corporate names appearing in this manual may or may not be registered trademarks or
copyrights of their respective companies, and are used only for identification or explanation and to the
owners’ benefit, without intent to infringe.

iii
Contents
Safety information....................................................................................................... v
About this guide......................................................................................................... vi
ROG STRIX B650E-E GAMING WIFI specifications summary .............................. vii
Connectors with shared bandwidth ......................................................................... xi
Package contents...................................................................................................... xii
Installation tools and components......................................................................... xiii
Chapter 1: Product Introduction
1.1 Before you proceed ................................................................................... 1-1
1.2 Motherboard layout.................................................................................... 1-2
Chapter 2: Basic Installation
2.1 Building your PC system...........................................................................2-1
2.1.1 CPU installation...........................................................................2-1
2.1.2 Cooling system installation..........................................................2-3
2.1.3 DIMM installation.........................................................................2-6
2.1.4 M.2 installation ............................................................................2-7
2.1.5 Motherboard installation............................................................2-12
2.1.6 ATX power connection..............................................................2-13
2.1.7 SATA device connection...........................................................2-14
2.1.8 Front I/O connector ................................................................... 2-15
2.1.9 Expansion card installation .......................................................2-16
2.1.10 Wi-Fi moving antenna installation ............................................. 2-19
2.2 BIOS update utility................................................................................... 2-20
2.3 Clear CMOS button .................................................................................. 2-21
2.4 Motherboard rear and audio connections ............................................. 2-22
2.4.1 Rear I/O connection .................................................................. 2-22
2.3.2 Audio I/O connections...............................................................2-23
2.4 Starting up for the first time.................................................................... 2-26
2.5 Turning off the computer ........................................................................ 2-26
Chapter 3: BIOS and RAID Support
3.1 Knowing BIOS ............................................................................................ 3-1
3.2 BIOS Setup program.................................................................................. 3-2
3.3 ASUS EZ Flash 3 ........................................................................................ 3-3
3.4 ASUS CrashFree BIOS 3............................................................................3-4
3.5 RAID configurations .................................................................................. 3-5

iv
Appendix
Q-Code table............................................................................................................ A-1
Notices .................................................................................................................... A-5
Warranty................................................................................................................. A-16
ASUS contact information.................................................................................... A-18
Service and Support ............................................................................................. A-18

v
Safety information
Electrical safety
• To prevent electrical shock hazard, disconnect the power cable from the electrical
outlet before relocating the system.
• When adding or removing devices to or from the system, ensure that the power cables
for the devices are unplugged before the signal cables are connected. If possible,
disconnect all power cables from the existing system before you add a device.
• Before connecting or removing signal cables from the motherboard, ensure that all
power cables are unplugged.
• Seek professional assistance before using an adapter or extension cord. These
devices could interrupt the grounding circuit.
• Ensure that your power supply is set to the correct voltage in your area. If you are not
sure about the voltage of the electrical outlet you are using, contact your local power
company.
• If the power supply is broken, do not try to fix it by yourself. Contact a qualified service
technician or your retailer.
Operation safety
• Before installing the motherboard and adding devices on it, carefully read all the
manuals that came with the package.
• Before using the product, ensure all cables are correctly connected and the power
cables are not damaged. If you detect any damage, contact your dealer immediately.
• To avoid short circuits, keep paper clips, screws, and staples away from connectors,
slots, sockets and circuitry.
• Avoid dust, humidity, and temperature extremes. Do not place the product in any area
where it may become wet.
• Place the product on a stable surface.
• If you encounter technical problems with the product, contact a qualified service
technician or your retailer.
• Your motherboard should only be used in environments with ambient temperatures
between 0°C and 40°C.
Button/Coin Batteries Safety Information
WARNING
KEEP OUT OF REACH OF CHILDREN
Swallowing can lead to chemical burns,
perforation of soft tissue, and death. Severe
burns can occur within 2 hours of ingestion.
Seek medical attention immediately.

vi
About this guide
This user guide contains the information you need when installing and configuring the
motherboard.
How this guide is organized
This guide contains the following parts:
• Chapter 1: Product Introduction
This chapter describes the features of the motherboard and the new technology it
supports. It includes description of the switches, jumpers, and connectors on the
motherboard.
• Chapter 2: Basic Installation
This chapter lists the hardware setup procedures that you have to perform when
installing system components.
• Chapter 3: BIOS and RAID Support
This chapter tells how to boot into the BIOS, upgrade BIOS using the EZ Flash Utility
and support on RAID.
Where to find more information
Refer to the following sources for additional information and for product and software
updates.
1. ASUS website
The ASUS website (www.asus.com) provides updated information on ASUS hardware
and software products.
2. Optional documentation
Your product package may include optional documentation, such as warranty flyers,
that may have been added by your dealer. These documents are not part of the
standard package.
Conventions used in this guide
To ensure that you perform certain tasks properly, take note of the following symbols used
throughout this user guide.
CAUTION: Information to prevent damage to the components and injuries to
yourself when trying to complete a task.
IMPORTANT: Instructions that you MUST follow to complete a task.
NOTE: Tips and additional information to help you complete a task.

vii
ROG STRIX B650E-E GAMING WIFI specifications
summary
CPU AMD Socket AM5 for AMD Ryzen™ 7000 Series Desktop Processors*
* Refer to www.asus.com for CPU support list.
Chipset AMD B650 Chipset
Memory
4 x DIMM, Max. 128GB, DDR5 6400+(OC)/ 6200(OC)/ 6000(OC)/
5800(OC)/ 5600(OC)/ 5400(OC)/ 5200/ 5000/ 4800 ECC and Non-ECC,
Un-buffered Memory*
Dual Channel Memory Architecture
Supports AMD EXTended Profiles for Overclocking (EXPO™)
OptiMem II
* Supported memory types, data rate(Speed), and number of DRAM module vary
depending on the CPU and memory configuration, for more information refer
to www.asus.com for memory support list.
* Non-ECC, Un-buffered DDR5 Memory supports On-Die ECC function.
Graphics
1 x DisplayPort*
1 x HDMI®port**
* Supports max. 8K@60Hz as specified in DisplayPort 1.4.
**Supports 4K@60Hz as specified in HDMI®2.1.
Expansion Slots
AMD Ryzen™ 7000 Series Desktop Processors*
2 x PCIe 5.0 x16 slots (support x16 or x8/x4 modes)**
AMD B650 Chipset
1 x PCIe 4.0 x16 slot (supports x4 mode)
* Please check the PCIe bifurcation table at
https://www.asus.com/support/FAQ/1037507/.
**When M.2_3 is occupied with an SSD device, PCIEX16_1 will run x8 only.
Storage
Total supports 4 x M.2 slots and 4 x SATA 6Gb/s ports*
AMD Ryzen™ 7000 Series Desktop Processors
M.2_1 slot (Key M), type 2242/2260/2280
(supports PCIe 5.0 x4 mode)
M.2_2 slot (Key M), type 2242/2260/2280
(supports PCIe 4.0 x4 mode)
M.2_3 slot (Key M), type 2242/2260/2280/22110
(supports PCIe 5.0 x4 mode)
AMD B650 Chipset
M.2_4 slot (Key M), type 2242/2260/2280
(supports PCIe 4.0 x4 mode)
4 x SATA 6Gb/s ports**
* AMD RAIDXpert2 Technology supports PCIe RAID 0/1/10.
** RAID configuration is not supported on the SATA6G_E1-4 ports.
Ethernet 1 x Intel®2.5Gb Ethernet
ASUS LANGuard
Wireless &
Bluetooth®
Wi-Fi 6E
2x2 Wi-Fi 6E (802.11 a/b/g/n/ac/ax)
Supports 2.4/5/6GHz frequency band
Bluetooth®v5.2
* WiFi 6E 6GHz regulatory may vary between countries.
(continued on the next page)

viii
ROG STRIX B650E-E GAMING WIFI specifications
summary
USB
Rear USB (Total 12 ports)
1 x USB 3.2 Gen 2x2 port (1 x USB Type-C®)
7 x USB 3.2 Gen 2 ports (6 x Type-A + 1 x USB Type-C®)
4 x USB 2.0 ports (4 x Type-A)
Front USB (Total 7 ports)
1 x USB 3.2 Gen 2 connector (supports USB Type-C®)
1 x USB 3.2 Gen 1 header supports 2 additional USB 3.2 Gen 1 ports
2 x USB 2.0 headers support 4 additional USB 2.0 ports
Audio
ROG SupremeFX 7.1 Surround Sound High Definition Audio CODEC
ALC4080
- Impedance sense for front and rear headphone outputs
- Supports: Jack-detection, Multi-streaming, Front Panel Jack-retasking
- High quality 120 dB SNR stereo playback output and 113 dB SNR
recording input
- Supports up to 32-Bit/384 kHz playback
Audio Features:
- Audio Shielding
- Savitech SV3H712 AMP
- Rear optical S/PDIF out port
- Premium audio capacitors
- Audio cover
Back Panel I/O Ports
1 x USB 3.2 Gen 2x2 port (1 x USB Type-C®)
7 x USB 3.2 Gen 2 ports (6 x Type-A + 1 x USB Type-C®)
4 x USB 2.0 ports (4 x Type-A)
1 x DisplayPort
1 x HDMI®port
1 x Wi-Fi Module
1 x Intel®2.5Gb Ethernet port
5 x Audio jacks
1 x Optical S/PDIF out port
1 x BIOS FlashBack™ button
1 x Clear CMOS button
Internal I/O Connectors
Fan and Cooling related
1 x 4-pin CPU Fan header
1 x 4-pin CPU OPT Fan header
1 x 4-pin AIO Pump header
5 x 4-pin Chassis Fan headers
Power related
1 x 24-pin Main Power connector
2 x 8-pin +12V Power connectors
Storage related
4 x M.2 slots (Key M)
4 x SATA 6Gb/s ports
(continued on the next page)

ix
ROG STRIX B650E-E GAMING WIFI specifications
summary
Internal I/O Connectors
USB
1 x USB 3.2 Gen 2 connector (supports USB Type-C®)
1 x USB 3.2 Gen 1 header supports 2 additional USB 3.2 Gen 1 ports
2 x USB 2.0 headers support 4 additional USB 2.0 ports
Miscellaneous
3 x Addressable Gen 2 headers
1 x Aura RGB header
1 x CPU Over Voltage jumper
1 x Front Panel Audio header (AAFP)
1 x 20-3 pin System Panel header with Chassis intrude function
1 x Thermal Sensor header
1 x Thunderbolt™ header
Special Features
Extreme Engine Digi+
- 5K Black Metallic Capacitors
ASUS Q-Design
- M.2 Q-Latch
- PCIe Slot Q-Release
- Q-DIMM
- Q-LED (CPU [red], DRAM [yellow], VGA [white], Boot Device [yellow
green])
- Q-Slot
ASUS Thermal Solution
- M.2 heatsink
- VRM heatsink design
ASUS EZ DIY
- BIOS FlashBack™ button
- BIOS FlashBack™ LED
- ProCool
- Pre-mounted I/O shield
- SafeSlot
- SafeDIMM
Aura Sync
- Aura RGB header
- Addressable Gen 2 header
Software Features
ROG Exclusive Software
- GameFirst VI
- ROG CPU-Z
- Sonic Studio III + Sonic Studio Virtual Mixer + Sonic Suite
Companion
- Sonic Radar III
(continued on the next page)

x
ROG STRIX B650E-E GAMING WIFI specifications
summary
Software Features
- DTS®Sound Unbound
- Anti-virus software
ASUS Exclusive Software
Armoury Crate
- AIDA64 Extreme (60 days free trial)
- Aura Creator
- Aura Sync
- Fan Xpert 4
- Power Saving
- Two-Way AI Noise Cancellation
AI Suite 3
- TPU
- DIGI+ VRM
- Turbo app
- PC Cleaner
MyASUS
WinRAR
UEFI BIOS
ASUS EZ DIY
- ASUS CrashFree BIOS 3
- ASUS EZ Flash 3
- ASUS UEFI BIOS EZ Mode
Dynamic OC Switcher
FlexKey
BIOS 256 Mb Flash ROM, UEFI AMI BIOS
Manageability WOL by PME, PXE
Operating System Windows®11, Windows®10 64-bit
Form Factor ATX Form Factor
12 inch x 9.6 inch (30.5 cm x 24.4 cm)
• Specifications are subject to change without notice. Please refer to the ASUS website
for the latest specifications.
• MyASUS offers a variety of support features such as helping to troubleshoot issues,
optimizing product performance, integrating ASUS software, and recovery drive
creation. Please scan the QR Code for installation guide and FAQ.

xi
Connectors with shared bandwidth
DDR5 DIMM_A1 (64bit, 288-pin module) DDR5 DIMM_A2 (64bit, 288-pin module) DDR5 DIMM_B1 (64bit, 288-pin module) DDR5 DIMM_B2 (64bit, 288-pin module)
CPU_OPT AIO_PUMPCPU_FAN
M.2_4(SOCKET3) M.2_3(SOCKET3)
M.2_2(SOCKET3)
M.2_1(SOCKET3)
PANEL
AAFP
SATA6G_E12SATA6G_E34
ATX_PWR
U32G1_8_9
CHA_FAN5
CHA_FAN1 CHA_FAN2
CHA_FAN4
CHA_FAN3
AUDIO
Super
I/O
2280 2260 2242
22110 2280 2260 2242 2260
2280
2280
2242
22602242
PCIEX16_1
PCIEX16_2
PCIEX16_3
USB_E12 USB_E34
ADD GEN 2_3
ADD GEN 2_2
ADD GEN 2_1
CPU_OV
T_SENSOR
LAN_U32G2_11
BIOS_FLBK
CLRTC
USB_15_5
U32G2_E123
U2_1617U3G2_3E4
U32G2_C2
U32G2X2_C6
HDMI_DP
FLBK_LED
PLUG_8PIN_PWR
DIGI
+VRM
U32G2_C10
ATX_12V_2
ATX_12V_1
TB_HEADER
AMD
B650
X
PCIE SATA
5.0 X4 X
PCIE SATA
4.0 X4
M.2_3(SOCKET3)
PCIE SATA
5.0 X4 X
M.2_1(SOCKET3)
PCIE SATA
4.0 X4 X
M.2_2(SOCKET3)
Ethernet
RGB_HEADER
CPU
DRAM
VGA
BOOT
1st
256Mb
BIOS
BATTERY
SOCKET AM5
Q_CODE
M.2(WIFI)
A
A
Configuration 1
APCIEX16_1 x8
M.2_3 V
When M.2_3 is occupied with an SSD device, PCIEX16_1 will run x8 only.

xii
Package contents
Check your motherboard package for the following items.
Motherboard 1 x ROG STRIX B650E-E GAMING WIFI motherboard
Cables 2 x SATA 6Gb/s cables
Additional Cooling Kit 1 x Thermal pad for M.2
Miscellaneous
1 x ASUS Wi-Fi moving antennas
1 x Cable ties pack
1 x M.2 Q-Latch package
1 x ROG key chain
1 x ROG Strix sticker
1 x ROG Strix thank you card
2 x Rubber Packages for M.2
Documentation 1 x User guide
If any of the above items is damaged or missing, contact your retailer.

xiii
Installation tools and components
Phillips (cross) screwdriver
PC chassis Power supply unit
AMD AM5 CPU AMD AM5 compatible CPU Fan
DDR5 DIMM SATA hard disk drive
SATA optical disc drive (optional) Graphics card (optional)
M.2 SSD module (optional) Screws
The tools and components in the table above are not included in the motherboard
package.

xiv

ROG STRIX B650E-E GAMING WIFI 1-1
Chapter 1
Product Introduction
1
Chapter 1: Product Introduction
1.1 Before you proceed
Take note of the following precautions before you install motherboard components or
change any motherboard settings.
• Unplug the power cord from the wall socket before touching any component.
• Before handling components, use a grounded wrist strap or touch a safely grounded
object or a metal object, such as the power supply case, to avoid damaging them due
to static electricity.
• Hold components by the edges to avoid touching the ICs on them.
• Whenever you uninstall any component, place it on a grounded antistatic pad or in
the bag that came with the component.
• Before you install or remove any component, ensure that the ATX power supply is
switched off or the power cord is detached from the power supply. Failure to do so
may cause severe damage to the motherboard, peripherals, or components.
• The pin definitions in this chapter are for reference only. The pin names depend on
the location of the header/jumper/connector.
• For more information on installing your motherboard, please scan the QR code
below:

1-2 Chapter 1: Product Introduction
Chapter 1
1.2 Motherboard layout
DDR5 DIMM_A1 (64bit, 288-pin module) DDR5 DIMM_A2 (64bit, 288-pin module) DDR5 DIMM_B1 (64bit, 288-pin module) DDR5 DIMM_B2 (64bit, 288-pin module)
CPU_OPT AIO_PUMPCPU_FAN
M.2_4(SOCKET3) M.2_3(SOCKET3)
M.2_2(SOCKET3)
M.2_1(SOCKET3)
PANEL
AAFP
SATA6G_E12SATA6G_E34
ATX_PWR
U32G1_8_9
CHA_FAN5
CHA_FAN1 CHA_FAN2
CHA_FAN4
CHA_FAN3
AUDIO
Super
I/O
2280 2260 2242
22110 2280 2260 2242 2260
2280
2280
2242
22602242
PCIEX16_1
PCIEX16_2
PCIEX16_3
USB_E12 USB_E34
ADD GEN 2_3
ADD GEN 2_2
ADD GEN 2_1
CPU_OV
T_SENSOR
LAN_U32G2_11
BIOS_FLBK
CLRTC
USB_15_5
U32G2_E123
U2_1617U3G2_3E4
U32G2_C2
U32G2X2_C6
HDMI_DP
FLBK_LED
PLUG_8PIN_PWR
DIGI
+VRM
24.4cm(9.6in)
30.5cm(12in)
U32G2_C10
ATX_12V_2
ATX_12V_1
TB_HEADER
AMD
B650
X
PCIE SATA
5.0 X4 X
PCIE SATA
4.0 X4
M.2_3(SOCKET3)
PCIE SATA
5.0 X4 X
M.2_1(SOCKET3)
PCIE SATA
4.0 X4 X
M.2_2(SOCKET3)
Ethernet
RGB_HEADER
CPU
DRAM
VGA
BOOT
1st
256Mb
BIOS
BATTERY
SOCKET AM5
Q_CODE
M.2(WIFI)
9
4
8
5
7
6
3
4
5 216
410414 17 16 1511
11
20
21
1213
4
18
19

ROG STRIX B650E-E GAMING WIFI 1-3
Chapter 1
Layout contents Page
1. CPU socket 1-4
2. DIMM slots 1-5
3. Expansion slots 1-7
4. Fan and Pump headers 1-9
5. Power connectors 1-10
6. M.2 slots (SOCKET 3) 1-11
7. SATA 6Gb/s ports 1-12
8. USB 3.2 Gen 2 Type-C®Front Panel connector 1-13
9. USB 3.2 Gen 1 header 1-13
10. USB 2.0 headers 1-14
11. Addressable Gen 2 headers 1-15
12. Aura RGB header 1-16
13. CPU Over Voltage jumper 1-17
14. Front Panel Audio header 1-17
15. System Panel header 1-18
16. Thermal Sensor header 1-19
17. Thunderbolt™ header 1-20
18. BIOS FlashBack™ LED 1-21
19. 8-Pin Power Plug LED 1-21
20. Q-Code LED 1-22
21. Q-LEDs 1-22

1-4 Chapter 1: Product Introduction
Chapter 1
1. CPU socket
The motherboard comes with an AM5 socket designed for AMD Ryzen™ 7000 Series
Desktop Processors.
SOCKET AM5
• The AM5 socket has a different pinout design. Ensure that you use a CPU designed
for the AM5 socket.
• The CPU fits in only one correct orientation. DO NOT force the CPU into the socket
to prevent bending the connectors on the socket and damaging the CPU.
• Ensure that all power cables are unplugged before installing the CPU.
• Upon purchase of the motherboard, ensure that the PnP cap is on the socket and
the socket contacts are not bent. Contact your retailer immediately if the PnP cap
is missing, or if you see any damage to the PnP cap/socket contacts/motherboard
components. ASUS will shoulder the cost of repair only if the damage is shipment/
transit-related.
• Keep the cap after installing the motherboard. ASUS will process Return
Merchandise Authorization (RMA) requests only if the motherboard comes with the
cap on the AM5 socket.
• The product warranty does not cover damage to the socket contacts resulting from
incorrect CPU installation/removal, or misplacement/loss/incorrect removal of the
PnP cap.

ROG STRIX B650E-E GAMING WIFI 1-5
Chapter 1
2. DIMM slots
The motherboard comes with Dual Inline Memory Modules (DIMM) slots designed for DDR5
(Double Data Rate 5) memory modules.
A DDR5 memory module is notched differently from a DDR, DDR2, DDR3 or DDR4
module. DO NOT install a DDR, DDR2, DDR3 or DDR4 memory module to the DDR5 slot.
DIMM_B1 DIMM_B2 DIMM_A1 DIMM_A2
1st
Recommended memory configurations
DIMM_A2
DIMM_B2
DIMM_A2
DIMM_A1
DIMM_A2
DIMM_B1
DIMM_B2

1-6 Chapter 1: Product Introduction
Chapter 1
Memory configurations
You may install 8 GB, 16 GB, and 32 GB unbuffered, ECC or non-ECC DDR5 DIMMs into
the DIMM sockets.
You may install varying memory sizes in Channel A and Channel B. The system maps
the total size of the lower-sized channel for the dual-channel configuration. Any excess
memory from the higher-sized channel is then mapped for single-channel operation.
• The default memory operation frequency is dependent on its Serial Presence Detect
(SPD), which is the standard way of accessing information from a memory module.
Under the default state, some memory modules for overclocking may operate at a
lower frequency than the vendor-marked value.
• For system stability, use a more efficient memory cooling system to support a full
memory load or overclocking condition.
• Always install the DIMMs with the same CAS Latency. For an optimum compatibility,
we recommend that you install memory modules of the same version or data code
(D/C) from the same vendor. Check with the vendor to get the correct memory
modules.
• Visit the ASUS website for the latest QVL, and memory frequency support depends
on the CPU types.