Asus TUF GAMING B650M-E WIFI User manual

Motherboard
TUF GAMING
B650M-E WIFI

ii
E21820
First Edition
April 2023
Copyright © 2023 ASUSTeK COMPUTER INC. All Rights Reserved.
No part of this manual, including the products and software described in it, may be reproduced,
transmitted, transcribed, stored in a retrieval system, or translated into any language in any form or by any
means, except documentation kept by the purchaser for backup purposes, without the express written
permission of ASUSTeK COMPUTER INC. (“ASUS”).
Product warranty or service will not be extended if: (1) the product is repaired, modied or altered, unless
such repair, modication of alteration is authorized in writing by ASUS; or (2) the serial number of the
product is defaced or missing.
ASUS PROVIDES THIS MANUAL “AS IS” WITHOUT WARRANTY OF ANY KIND, EITHER EXPRESS
OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE IMPLIED WARRANTIES OR CONDITIONS OF
MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. IN NO EVENT SHALL ASUS, ITS
DIRECTORS, OFFICERS, EMPLOYEES OR AGENTS BE LIABLE FOR ANY INDIRECT, SPECIAL,
INCIDENTAL, OR CONSEQUENTIAL DAMAGES (INCLUDING DAMAGES FOR LOSS OF PROFITS,
LOSS OF BUSINESS, LOSS OF USE OR DATA, INTERRUPTION OF BUSINESS AND THE LIKE),
EVEN IF ASUS HAS BEEN ADVISED OF THE POSSIBILITY OF SUCH DAMAGES ARISING FROM ANY
DEFECT OR ERROR IN THIS MANUAL OR PRODUCT.
SPECIFICATIONS AND INFORMATION CONTAINED IN THIS MANUAL ARE FURNISHED FOR
INFORMATIONAL USE ONLY, AND ARE SUBJECT TO CHANGE AT ANY TIME WITHOUT NOTICE,
AND SHOULD NOT BE CONSTRUED AS A COMMITMENT BY ASUS. ASUS ASSUMES NO
RESPONSIBILITY OR LIABILITY FOR ANY ERRORS OR INACCURACIES THAT MAY APPEAR IN THIS
MANUAL, INCLUDING THE PRODUCTS AND SOFTWARE DESCRIBED IN IT.
Products and corporate names appearing in this manual may or may not be registered trademarks or
copyrights of their respective companies, and are used only for identication or explanation and to the
owners’ benet, without intent to infringe.

iii
Contents
Safety information...................................................................................................... iv
About this guide.......................................................................................................... v
Package contents....................................................................................................... vi
TUF GAMING B650M-E WIFI specications summary............................................ vi
Chapter 1: Product Introduction
1.1 Before you proceed...................................................................................... 1-1
1.2 Motherboard overview ................................................................................. 1-2
1.3 Central Processing Unit (CPU).................................................................... 1-9
1.4 System memory.......................................................................................... 1-10
1.5 M.2 installation............................................................................................ 1-12
1.6 Wi-Fi antennas installation........................................................................ 1-16
Chapter 2: BIOS and RAID Support
2.1 Knowing BIOS............................................................................................... 2-1
2.2 BIOS Setup program .................................................................................... 2-2
2.3 ASUS EZ Flash 3........................................................................................... 2-3
2.4 ASUS CrashFree BIOS 3.............................................................................. 2-4
2.5 RAID congurations..................................................................................... 2-5
Appendix
Notices ..................................................................................................................... A-1
Warranty................................................................................................................... A-9
ASUS contact information.................................................................................... A-11
Service and Support ............................................................................................. A-11

iv
Safety information
Electrical safety
• To prevent electrical shock hazard, disconnect the power cable from the electrical outlet
before relocating the system.
• When adding or removing devices to or from the system, ensure that the power cables
for the devices are unplugged before the signal cables are connected. If possible,
disconnect all power cables from the existing system before you add a device.
• Before connecting or removing signal cables from the motherboard, ensure that all power
cables are unplugged.
• Seek professional assistance before using an adapter or extension cord. These devices
could interrupt the grounding circuit.
• Ensure that your power supply is set to the correct voltage in your area. If you are not
sure about the voltage of the electrical outlet you are using, contact your local power
company.
• If the power supply is broken, do not try to x it by yourself. Contact a qualied service
technician or your retailer.
Operation safety
• Before installing the motherboard and adding components, carefully read all the manuals
that came with the package.
• Before using the product, ensure all cables are correctly connected and the power cables
are not damaged. If you detect any damage, contact your dealer immediately.
• To avoid short circuits, keep paper clips, screws, and staples away from connectors,
slots, sockets and circuitry.
• Avoid dust, humidity, and temperature extremes. Do not place the product in any area
where it may become wet.
• Place the product on a stable surface.
• If you encounter technical problems with the product, contact a qualied service
technician or your retailer.
• Your motherboard should only be used in environments with ambient temperatures
between 0°C and 40°C.
Button/Coin Batteries Safety Information
WARNING
KEEP OUT OF REACH OF CHILDREN
Swallowing can lead to chemical burns,
perforation of soft tissue, and death.
Severe burns can occur within 2 hours
of ingestion. Seek medical attention
immediately.

v
About this guide
This user guide contains the information you need when installing and conguring the
motherboard.
How this guide is organized
This guide contains the following parts:
• Chapter 1: Product Introduction
This chapter describes the features of the motherboard and the new technology it
supports. It includes descriptions of the switches, jumpers, and connectors on the
motherboard.
• Chapter 2: BIOS and RAID Support
This chapter tells how to boot into the BIOS, upgrade BIOS using the EZ Flash Utility
and support on RAID.
Where to nd more information
Refer to the following sources for additional information and for product and software
updates.
1. ASUS website
The ASUS website (www.asus.com) provides updated information on ASUS hardware
and software products.
2. Optional documentation
Your product package may include optional documentation, such as warranty flyers,
that may have been added by your dealer. These documents are not part of the
standard package.
Conventions used in this guide
To ensure that you perform certain tasks properly, take note of the following symbols used
throughout this user guide.
CAUTION: Information to prevent damage to the components and injuries to
yourself when trying to complete a task.
IMPORTANT: Instructions that you MUST follow to complete a task.
NOTE: Tips and additional information to help you complete a task.

vi
TUF GAMING B650M-E WIFI specications summary
CPU AMD Socket AM5 for AMD Ryzen™ 7000 Series Desktop Processors*
* Refer to www.asus.com for CPU support list.
Chipset AMD B650
Memory
4 x DIMM slots, Max. 128GB, DDR5 ECC and Non-ECC, Un-buffered
Memory*
Dual Channel Memory Architecture
Supports AMD Extended Proles for Overclocking (EXPO™)
OptiMem II
* Supported memory types, data rate (Speed), and number of DRAM modules vary
depending on the CPU and memory conguration, for more information please
refer to CPU/Memory Support list under the Support tab of product information
site or visit https://www.asus.com/support/.
* Non-ECC, un-buffered DDR5 memory supports On-Die ECC function.
Graphics
2 x DisplayPort**
1 x HDMI™ port***
* Graphics specications may vary between CPU types. Please refer to AMD CPU
specications.
** Supports max. 8K@60Hz as specied in DisplayPort 1.4.
*** Supports 4K@60Hz as specied in HDMI™ 2.1.
Expansion Slots
AMD Ryzen™ 7000 Series Desktop Processors
1 x PCIe 4.0 x16 slot
AMD B650 Chipset
2 x PCIe 4.0 x1 slots
Note: To ensure compatibility of the device installed, please refer to
https://www.asus.com/support/ for the list of supported peripherals.
Storage
Total supports 2 x M.2 slots and 4 x SATA 6Gb/s ports*
AMD Ryzen™ 7000 Series Desktop Processors
M.2_1 slot (Key M), type 2242/2260/2280 (supports PCIe 5.0 x4 mode)
M.2_2 slot (Key M), type 2242/2260/2280 (supports PCIe 4.0 x4 mode)
AMD B650 Chipset
4 x SATA 6Gb/s ports
* AMD RAIDXpert2 Technology supports both PCIe RAID 0/1/10 and SATA RAID
0/1/10.
(continued on the next page)
Package contents
Check your motherboard package for the following items.
Motherboard 1 x TUF GAMING B650M-E WIFI motherboard
Cables 2 x SATA 6Gb/s cables
Miscellaneous
1 x ASUS Wi-Fi moving antennas
1 x M.2 Rubber package
1 x Screw package for M.2 SSD
Documentation 1 x TUF Certication card
1 x User guide
If any of the above items is damaged or missing, contact your retailer.

vii
TUF GAMING B650M-E WIFI specications summary
Ethernet 1 x Realtek 2.5Gb Ethernet
TUF LANGuard
Wireless & Bluetooth®
Wi-Fi 6
2x2 Wi-Fi 6 (802.11 a/b/g/n/ac/ax)
Supports 2.4/5GHz frequency band
Bluetooth® v5.2*
* The Bluetooth version may vary, please refer to the Wi-Fi module
manufacturer’s website for the latest specications.
USB
Rear USB (Total 8 ports)
2 x USB 3.2 Gen 2 (10G) ports (1 x Type-A + 1 x USB Type-C®)
2 x USB 3.2 Gen 1 (5G) ports (2 x Type-A)
4 x USB 2.0 ports (4 x Type-A)
Front USB (Total 7 ports)
1 x USB 3.2 Gen 1 (5G) connector (supports USB Type-C®)
1 x USB 3.2 Gen 1 (5G) header supports 2 additional USB 3.2 Gen 1
ports
2 x USB 2.0 headers support 4 additional USB 2.0 ports
Audio
Realtek 7.1 Surround Sound High Denition Audio CODEC*
- Supports: Jack-detection, Multi-streaming, Front Panel Jack-retasking
- Supports up to 24-Bit/192 kHz playback
Audio Features
- Audio Shielding
- Premium audio capacitors
- Dedicated audio PCB layers
* A chassis with an HD audio module in the front panel is required to support 7.1
Surround Sound audio output.
Back Panel I/O Ports
2 x USB 3.2 Gen 2 (10G) ports (1 x Type-A + 1 x USB Type-C®)
2 x USB 3.2 Gen 1 (5G) ports (2 x Type-A)
4 x USB 2.0 ports (4 x Type-A)
2 x DisplayPort
1 x HDMI™ port
1 x Wi-Fi Module
1 x Realtek 2.5Gb Ethernet port
3 x Audio jacks
1 x BIOS FlashBack™ button
1 x PS/2 Keyboard/Mouse combo port
Internal I/O
Connectors
Fan and Cooling related
1 x 4-pin CPU Fan header
1 x 4-pin CPU OPT Fan header
1 x 4-pin AIO Pump header
2 x 4-pin Chassis Fan headers
Power related
1 x 24-pin Main Power connector
1 x 8-pin +12V Power connector
1 x 4-pin +12V Power connector
(continued on the next page)

viii
TUF GAMING B650M-E WIFI specications summary
Internal I/O
Connectors
Storage related
2 x M.2 slots (Key M)
4 x SATA 6Gb/s ports
USB
1 x USB 3.2 Gen 1 (5G) connector (supports USB Type-C®)
1 x USB 3.2 Gen 1 (5G) header supports 2 additional USB 3.2 Gen 1 ports
2 x USB 2.0 headers support 4 additional USB 2.0 ports
Miscellaneous
3 x Addressable Gen 2 headers
1 x Aura RGB header
1 x Clear CMOS header
1 x COM Port header
1 x Front Panel Audio header (AAFP)
1 x 20-3 pin System Panel header with Chassis intrude function
Special Features
ASUS TUF PROTECTION
- DIGI+ VRM (- Digital power design with DrMOS)
- ESD Guards
- TUF LANGuard
- Overvoltage Protection
- SafeSlot Core+
- Stainless-Steel Back I/O
ASUS Q-Design
- M.2 Q-Latch
- Q-DIMM
- Q-LED (CPU [red], DRAM [yellow], VGA [white], Boot Device [yellow
green])
- Q-Slot
ASUS Thermal Solution
- M.2 heatsink
- VRM heatsink design
ASUS EZ DIY
- BIOS FlashBack™ button
- BIOS FlashBack™ LED
- ProCool
- Pre-mounted I/O shield
- SafeSlot Core+
- SafeDIMM
Aura Sync
- Aura RGB header
- Addressable Gen 2 headers
(continued on the next page)

ix
TUF GAMING B650M-E WIFI specications summary
Software Features
ASUS Exclusive Software
Armoury Crate
- Aura Creator
- Aura Sync
- Fan Xpert 2+
- Power Saving
- Two-Way AI Noise Cancelation
AI Suite 3
- TurboV EVO
- DIGI+ VRM
- PC Cleaner
TUF GAMING CPU-Z
DTS Audio Processing
MyASUS
Norton 360 for Gamers (60 Days Free Trial)
WinRAR
UEFI BIOS
ASUS EZ DIY
- ASUS CrashFree BIOS 3
- ASUS EZ Flash 3
- ASUS UEFI BIOS EZ Mode
BIOS 256 Mb Flash ROM, UEFI AMI BIOS
Manageability WOL by PME, PXE
Operating System Windows®11, Windows®10 64-bit
Form Factor mATX Form Factor
9.6 inch x 9.6 inch (24.4 cm x 24.4 cm)
• Specifications are subject to change without notice. Please refer to the ASUS website
for the latest specifications.
• MyASUS offers a variety of support features such as helping to troubleshoot issues,
optimizing product performance, integrating ASUS software, and recovery drive
creation. Please scan the QR Code for installation guide and FAQ.
• For more information on downloading and installing drivers and utilities for your
motherboard, please scan the QR code below:

x

1-1
1
TUF GAMING B650M-E WIFI
Product Introduction
1.1 Before you proceed
Take note of the following precautions before you install motherboard components or change
any motherboard settings.
• Unplug the power cord from the wall socket before touching any component.
• Before handling components, use a grounded wrist strap or touch a safely grounded
object or a metal object, such as the power supply case, to avoid damaging them due
to static electricity.
• Hold components by the edges to avoid touching the ICs on them.
• Whenever you uninstall any component, place it on a grounded antistatic pad or in the
bag that came with the component.
• Before you install or remove any component, ensure that the ATX power supply is
switched off or the power cord is detached from the power supply. Failure to do so
may cause severe damage to the motherboard, peripherals, or components.
• The pin definitions in this chapter are for reference only. The pin names depend on the
location of the header/jumper/connector.
• For more information on installing your motherboard, please scan the QR code below:
Chapter 1: Product Introduction

1-2
1.2.1 Layout contents
1. CPU socket
The motherboard comes with an AMD Socket AM5 designed for AMD Ryzen™ 7000 Series
Desktop Processors.
For more details, refer to Central Processing Unit (CPU).
2. DDR5 DIMM slots
The motherboard comes with Dual Inline Memory Modules (DIMM) slots designed for DDR5
(Double Data Rate 5) memory modules.
For more details, refer to System memory.
3. Expansion slots
This motherboard supports one PCIe 4.0 x16 graphics cards and two PCIe 4.0 x1 network
cards, SCSI cards or other cards that complies with the PCI Express specication.
Chapter 1: Product Introduction
1.2 Motherboard overview
7
DDR5 DIMM_A1 (64bit, 288-pin module) DDR5 DIMM_A2 (64bit, 288-pin module) DDR5 DIMM_B1 (64bit, 288-pin module) DDR5 DIMM_B2 (64bit, 288-pin module)
CPU
DRAM
VGA
BOOT
CPU_OPT
AIO_PUMP
CPU_FAN
CHA_FAN2
CHA_FAN1
COM PANEL
AAFP
SATA6G_1SATA6G_2SATA6G_3
ATX_PWR
U32G1_89
Super
I/O
2280 2260 2242
2280 2260 2242
PCIEX16
PCIEX1_1
PCIEX1_2
USB_1415 USB_1617
RGB_HEADER
ADD_GEN 2_3 CLRTC
LAN_U32G2_6
U32G2_C7
KBMS
_U32G1_34
USB_5_1_2_13
HDMI_DP1
DP2
DIGI
+VRM
24.4cm(9.6in)
24.4cm(9.6in)
BATTERY
U32_C10
SOCKET AM5
ATX_12V_2 ATX_12V_1
AMD
B650
X
PCIE SATA
4.0 X4
PCIE SATA
5.0 X4 X
M.2_1(SOCKET3)
Audio
Codec
Ethernet
256Mb
BIOS
ADD_GEN 2_1
ADD_GEN 2_2
1st
AUDIO
M.2(WIFI)
BIOS_FLBK
FLBK_LED
SATA6G_4
M.2_2(SOCKET3) M.2_1(SOCKET3) M.2_2(SOCKET3)
5
18
8
6
9
415 14
17
3
4
2
4 1115
161110 127
7
13
Unplug the power cord before installing or removing the motherboard. Failure to do so can
cause you physical injury and damage motherboard components.

1-3
4. Fan headers
The Fan headers allow you to connect fans to cool the system.
Header Max.
Current Max. Power Default Speed Shared
Control
CPU_FAN 1A 12W Q-Fan Controlled A
CPU_OPT 1A 12W Q-Fan Controlled A
CHA_FAN1 1A 12W Q-Fan Controlled -
CHA_FAN2 1A 12W Q-Fan Controlled -
AIO_PUMP 1A 12W Full-Speed -
5. Power connectors
These Power connectors allow you to connect your motherboard to a power supply. The
power supply plugs are designed to t in only one orientation. Find the proper orientation and
push down rmly until the power supply plugs are fully inserted.
Ensure to connect the 8-pin power plug or connect both the 8-pin and 4-pin power plugs.
We recommend that you use a PSU with a higher power output when conguring a system
with more power-consuming devices. The system may become unstable or may not boot
up if the power is inadequate.
6. M.2 slots (Key M)
The M.2 slots allow you to install M.2 devices such as M.2 SSD modules.
AMD Ryzen™ 7000 Series Desktop Processors
M.2_1 slot (Key M), type 2242/2260/2280 (supports PCIe 5.0 x4 mode)
M.2_2 slot (Key M), type 2242/2260/2280 (supports PCIe 4.0 x4 mode)
The M.2 SSD module is purchased separately.
7. SATA 6Gb/s ports
The SATA 6Gb/s ports allow you to connect SATA devices such as optical disc drives and
hard disk drives via SATA cables.
8. USB 3.2 Gen 1 Type-C®Front Panel connector
The USB 3.2 Gen 1 Type-C®connector allows you to connect a USB
3.2 Gen 1 Type-C®module for an additional USB 3.2 Gen 1 Type-C®
port on the front panel. The USB 3.2 Gen 1 Type-C®connector provides
data transfer speeds of up to 5 Gb/s.
The USB 3.2 Gen 1 Type-C®module is purchased separately.
FAN PWM
FAN IN
FAN PWR
GND
GND
FAN PWR
FAN IN
FAN PWM
FAN PWM
FAN IN
FAN PWR
GND
GND FAN PWR FAN IN FAN PWM
NC
NC
CC1
VBUS
RX1-
RX1+
GND
TX1-
TX1+
VBUS
VBUS
TX2+
TX2-
GND
RX2+
RX2-
GND
D-
D+
CC2
U32G2_C3
TUF GAMING B650M-E WIFI

1-4
9. USB 3.2 Gen 1 header
The USB 3.2 Gen 1 header allows you to connect a USB 3.2 Gen
1 module for additional USB 3.2 Gen 1 ports. The USB 3.2 Gen 1
header provides data transfer speeds of up to 5 Gb/s.
The USB 3.2 Gen 1 module is purchased separately.
10. USB 2.0 headers
The USB 2.0 headers allow you to connect USB modules for
additional USB 2.0 ports. The USB 2.0 headers provide data
transfer speeds of up to 480 Mb/s.
DO NOT connect a 1394 cable to the USB connectors.
Doing so will damage the motherboard!
The USB 2.0 module is purchased separately.
11. Addressable Gen 2 headers
The Addressable Gen 2 headers allow you to connect individually addressable
RGB WS2812B LED strips or WS2812B based LED strips.
The Addressable Gen 2 headers support WS2812B addressable RGB LED strips (5V/Data/
Ground), with a maximum power rating of 3A (5V), and the addressable headers on this
board can handle a combined maximum of 500 LEDs.
Before you install or remove any component, ensure that the power supply is switched off
or the power cord is detached from the power supply. Failure to do so may cause severe
damage to the motherboard, peripherals, or components.
• Actual lighting and color will vary with LED strip.
• If your LED strip does not light up, check if the addressable RGB LED strip is
connected in the correct orientation, and the 5V connector is aligned with the 5V
header on the motherboard.
• The addressable RGB LED strip will only light up when the system is powered on.
• The addressable RGB LED strip is purchased separately.
12. Aura RGB header
The Aura RGB header allows you to connect RGB LED strips.
The Aura RGB header supports 5050 RGB multi-color LED strips (12V/G/R/B), with a
maximum power rating of 3A (12V).
Before you install or remove any component, ensure that the ATX power supply is switched
off or the power cord is detached from the power supply. Failure to do so may cause severe
damage to the motherboard, peripherals, or components.
USB3+5V
IntA_E3_SSRX-
IntA_E3_SSRX+
GND
IntA_E3_SSTX-
IntA_E3_SSTX+
GND
IntA_E3_D-
IntA_E3_D+
GND
PIN 1
USB3+5V
IntA_E4_SSRX-
IntA_E4_SSRX+
GND
IntA_E4_SSTX-
IntA_E4_SSTX+
GND
IntA_E4_D-
IntA_E4_D+
U32G1_E34
USB+5V
USB_P7- USB_P7+
GND NC
USB+5V
USB_P8-
USB_P8+
GND
PIN 1
USB_78
USB+5V
USB_P9- USB_P9+
GND NC
USB+5V
USB_P10-
USB_P10+
GND
PIN 1
USB_910
ADD_GEN 2
+5V
Data
Ground
PIN 1
Chapter 1: Product Introduction

1-5
• Actual lighting and color will vary with LED strip.
• If your LED strip does not light up, check if the RGB LED extension cable and the
RGB LED strip are connected in the correct orientation, and the 12V connector is
aligned with the 12V header on the motherboard.
• The LED strip will only light up when the system is powered on.
• The LED strip is purchased separately.
13. Clear CMOS header
The Clear CMOS header allows you to clear the Real Time Clock (RTC) RAM in
the CMOS, which contains the date, time, system passwords, and system setup
parameters.
To erase the RTC RAM:
1. Turn OFF the computer and unplug the power cord.
2. Short-circuit pin 1-2 with a metal object or jumper cap for about 5-10 seconds.
3. Plug the power cord and turn ON the computer.
4. Hold down the <Del> key during the boot process and enter BIOS setup to
re-enter data.
DO NOT short-circuit the pins except when clearing the RTC RAM. Short-circuiting or
placing a jumper cap will cause system boot failure!
If the steps above do not help, remove the onboard button cell battery and short the two
pins again to clear the CMOS RTC RAM data. After clearing the CMOS, reinstall the button
cell battery.
14. COM Port header
This header is for a serial (COM) port. Connect the serial port module cable to
this header, then install the module to a slot opening at the back of the system
chassis.
The COM Port module is purchased separately.
15. Front Panel Audio header
The Front Panel Audio header is for a chassis-mounted front panel audio
I/O module that supports HD Audio. Connect one end of the front panel
audio I/O module cable to this header.
We recommend that you connect a high-denition front panel audio
module to this header to avail of the motherboard’s high-denition
audio capability.
CLRTC
+3V_BAT GND
PIN 1
PIN 1
COM
DCD
TXD
GND
RTS
RI
RXD
DTR
DSR
CTS
PORT1L
PORT1R PORT2R
SENSE_SEND
PORT2L
AGND NC SENSE1_RETUR SENSE2_RETUR
AAFP
PIN 1
HD-audio-compliant
pin definition
TUF GAMING B650M-E WIFI

1-6
16. System Panel header
This header supports several chassis-mounted functions.
• System Power LED header (PLED)
The 2-pin and/or 3-1 pin headers allow you to connect the
System Power LED. The System Power LED lights up when
the system is connected to a power source, or when you
turn on the system power, and blinks when the system is in
sleep mode.
• Storage Device Activity LED header (HDD_LED)
The 2-pin header allows you to connect the Storage Device Activity LED. The Storage
Device Activity LED lights up or blinks when data is read from or written to the storage
device or storage device add-on card.
• System Warning Speaker header (SPEAKER)
The 4-pin header allows you to connect the chassis-mounted system warning speaker.
The speaker allows you to hear system beeps and warnings.
• Power Button/Soft-off Button header (PWRSW)
The 2-pin header allows you to connect the system power button. Press the power
button to power up the system, or put the system into sleep or soft-off mode
(depending on the operating system settings).
• Reset button header (RESET)
The 2-pin header allows you to connect the chassis-mounted reset button. Press the
reset button to reboot the system.
• Chassis intrusion header (CHASSIS)
The 2-pin header allows you to connect the chassis-mounted intrusion detection
sensor or switch. The chassis intrusion sensor or switch sends a high-level signal
to the header when a chassis component is removed or replaced, the signal is then
generated as a chassis intrusion event.
17. BIOS FlashBackTM LED
The BIOS FlashBack™ LED lights up or blinks to indicate the status of
the BIOS FlashBack™.
Scan the QR code for more information on BIOS FlashBackTM
function.
18. Q-LEDs
The Q-LEDs check key components (CPU, DRAM, VGA, and booting devices) during the
motherboard booting process. If an error is found, the critical component’s LED stays lit up
until the problem is solved.
The Q-LEDs provide the most probable cause of an error code as a starting point for
troubleshooting. The actual cause may vary from case to case.
Chapter 1: Product Introduction

1-7
1.2.2 Rear panel connectors
6 7 8 9 10 11 12 13 14
1 2 3 4 5
1. DisplayPort. These ports are for DisplayPort-compatible devices.
2. PS/2 Keyboard/Mouse combo port. This port is for a PS/2 keyboard or mouse.
3. 2.5Gb Ethernet port. This port allows 2.5Gbps Ethernet connection to a Local Area
Network (LAN) through a network hub. Refer to the table below for the Ethernet port
LED indications.
Realtek 2.5Gb Ethernet port LED indications
Speed LED
Status Description
OFF No link
GREEN 2.5 Gbps connection
ORANGE 1 Gbps / 100 Mbps /
10 Mbps connection
Activity Link LED
Status Description
OFF No link
GREEN Linked
BLINKING Data activity
ACT/LINK
LED
SPEED
LED
Ethernet port
4. Line In port (light blue). This port connects the tape, CD, DVD player, or other audio
sources.
5. Line Out port (lime). This port connects a headphone or a speaker. In 4-channel,
5.1-channel, and 7.1-channel congurations, the function of this port becomes Front
Speaker Out.
6. HDMI™ port. This port is for a High-Denition Multimedia Interface (HDMI™)
connector, and is HDCP compliant allowing playback of HD DVD, Blu-ray, and other
protected content.
7. BIOS FlashBackTM button. Press the BIOS FlashBackTM button for three seconds until
the FlashBackTM LED blinks three times, indicating that the BIOS FlashBackTM function
is enabled.
To use BIOS FlashBack™:
1) Visit https://www.asus.com/support/ and download the latest BIOS version for this
motherboard.
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2) Manually rename the le as A5463.CAP, or launch the BIOSRenamer.exe application
to automatically rename the le, then copy it to your USB storage device. The
BIOSRenamer.exe application is zipped together with your BIOS le when you
download a BIOS le for a BIOS FlashBack™ compatible motherboard.
3) Plug the 24-pin power connector to the motherboard and turn on the power supply (No
need to power on the system). Insert the USB storage device to the USB 2.0 port with
BIOS FlashBack™ function.
4) Press the BIOS FlashBack™ button for three (3) seconds until the BIOS FlashBack™
LED blinks three times, indicating that the BIOS FlashBack™ function is enabled.
5) Wait until the light goes out, indicating that the BIOS updating process is completed.
8. USB 3.2 Gen 1 (up to 5Gbps) ports. These Universal Serial Bus (USB) ports connect
to USB 3.2 Gen 1 devices.
9. USB 2.0 port with BIOS FlashBack™ function. Insert a USB storage device to this
Universal Serial Bus (USB) port to run BIOS FlashBack™.
10. USB 2.0 ports. These Universal Serial Bus (USB) ports are for USB 2.0 devices.
11. USB 3.2 Gen 2 (up to 10Gbps) ports (teal blue, Type A). These Universal Serial Bus
3.2 (USB 3.2) ports are for USB 3.2 Gen 2 devices.
12. USB 3.2 Gen 2 (up to 10Gbps) port (USB Type-C®). This Universal Serial Bus 3.2
(USB 3.2) port is for USB 3.2 Gen 2 Type-C®devices.
13. Wi-Fi 6 ports. Connect the bundled ASUS Wi-Fi antenna connectors to these ports.
• Ensure that the ASUS 2x2 dual band Wi-Fi antenna is securely installed to the Wi-Fi
ports.
• Ensure that the antenna is at least 20 cm away from all persons.
14. Microphone port (pink). This port connects a microphone.
Refer to the audio conguration table below for the function of the audio ports in 2, 4, 5.1,
or 7.1-channel conguration.
Audio 2, 4, 5.1 or 7.1-channel conguration
Port 2-channel 4-channel 5.1-channel 7.1-channel
Light Blue
(Rear panel) -Rear Speaker Out
Rear Speaker
Out
Rear Speaker
Out
Lime
(Rear panel)
Front Speaker
Out
Front Speaker
Out
Front Speaker
Out
Front Speaker
Out
Pink
(Rear panel) - - Center/Subwoofer Center/Subwoofer
Lime
(Front panel) - - - Side Speaker Out
Pink
(Front panel) ----
To configure a 7.1-channel audio output:
Use a chassis with HD audio module in the front panel to support a 7.1-channel audio
output.
Chapter 1: Product Introduction

1-9
1.3 Central Processing Unit (CPU)
This motherboard comes with an AMD Socket AM5 designed for AMD
Ryzen™ 7000 Series Desktop Processors.
Unplug all power cables before installing the CPU.
• The AM5 socket has a different pinout design. Ensure that you use a CPU designed
for the AM5 socket. The CPU fits in only one correct orientation. DO NOT force the
CPU into the socket to prevent bending the connectors on the socket and damaging
the CPU!
• ASUS will not cover damages resulting from incorrect CPU installation/removal,
incorrect CPU orientation/placement, or other damages resulting from negligence by
the user.
Installing the CPU
Apply the Thermal Interface Material to the CPU cooling system and CPU before you install
the cooling system, if necessary.
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1.4 System memory
This motherboard comes with four Double Data Rate 5 (DDR5) Dual Inline Memory Module
(DIMM) sockets. The gure illustrates the location of the DDR5 DIMM sockets:
Channel Sockets
Channel A DIMM_A1 & DIMM_A2
Channel B DIMM_B1 & DIMM_B2
DIMM_A1
DIMM_A2
DIMM_B1
DIMM_B2
1st
A DDR5 memory module is notched differently from a DDR, DDR2, DDR3, or DDR4
module. DO NOT install a DDR, DDR2, DDR3, or DDR4 memory module to the DDR5 slot.
• You may install varying memory sizes in Channel A and Channel B. The system
maps the total size of the lower-sized channel for the dual-channel conguration. Any
excess memory from the higher-sized channel is then mapped for single-channel
operation.
• You may install 8 GB, 16 GB, and 32 GB unbuffered, ECC and Non-ECC DDR5
DIMMs into the DIMM sockets.
• The default memory operation frequency is dependent on its Serial Presence Detect
(SPD), which is the standard way of accessing information from a memory module.
Under the default state, some memory modules for overclocking may operate at a
lower frequency than the vendor-marked value.
• For system stability, use a more efcient memory cooling system to support a full
memory load.
• Always install DIMMs with the same CAS latency. For optimal compatibility, we
recommend that you install memory modules of the same version or date code (D/C)
from the same vendor. Check with the retailer to get the correct memory modules.
• Supported memory types, data rate (speed), and number of DRAM modules vary
depending on the CPU and memory conguration, for more information please refer
to CPU/Memory Support list under the Support tab of product information site or visit
https://www.asus.com/support/.
Recommended memory congurations
DIMM_A2
DIMM_B2
DIMM_A2
DIMM_A1
DIMM_A2
DIMM_B1
DIMM_B2
Chapter 1: Product Introduction