National Instruments USB-6221 OEM User manual

USER GUIDE
NI USB-6221/6229/6251/6259 OEM
This document provides dimensions, pinouts, and information
about the connectors, switch, LEDs, and chassis ground of the
NI USB-6221/6229/6251/6259 OEM devices.
Caution There are no product safety, electromagnetic compatibility (EMC), or
CE marking compliance claims made for the USB-6221/6229/6251/6259 OEM devices.
Conformity to any and all compliance requirements rests with the end product supplier.
Figure 1 shows the USB-6221/6251 OEM and USB-6229/6259 OEM
devices.
Figure 1. USB-6221/6251 and USB-6229/6259 OEM Devices
Refer to the NI 622x Specifications document for USB-6221/6229
specifications and the NI 625x Specifications document for
USB-6251/6259 specifications. Refer to the M Series User Manual for
more information about USB-6221/6229/6251/6259 devices. You can find
all documentation at ni.com/manuals.
USB-6221/6251 USB-6229/6259

NI USB-6221/6229/6251/6259 OEM User Guide 2 ni.com
Dimensions
Figure 2 shows the dimensions of the USB-6221/6251 OEM device.
Figure 2. USB-6221/6251 OEM Dimensions in Inches (Millimeters)
0.436 (11.07)
0.392 (9.96)
0.362 (9.19)
0.162 (4.11)
0.062 (1.57)
0.000 (0.00)
0.396 (10.06)
0.304 (7.72)
0.256 (6.50)
0.116 (2.95)
0.000 (0.00)
6.950 (176.53)
4x 6.718 (170.63)
6.270 (159.26)
6.140 (155.96)
5.930 (150.62)
0.000 (0.00)
0.200 (5.08)
2.072 (52.63) 3.296 (83.72)
4.780 (121.41) 6.200 (157.48)
6.400 (162.56)
0.393 (9.98) 0.200 (5.08)
0.918 (23.32) 4.110 (104.39) 3.734 (94.84) 3.730 (94.74) 3.180 (80.77) 3.220 (81.79) 3.198 (81.22) 6.013 (152.74) 5.900 (149.86) 5.210 (132.33) 0.390 (9.91)
1.057 (26.85) 1.750 (44.45) 2.300 (58.42) 2.606 (66.19) 3.080 (78.23)
0.200 (5.08)
2.535 (64.39)
5.080 (129.03)
5.290 (134.37)
5.760 (146.30)
6.140 (155.96)
0.304 (7.72)
0.515 (13.08)
2X Ø 0.140 Cutout
in Panel for LEDs
Ø 0.330 Cutout in Panel
for Power Connector
2X Ø 0.156 (3.96)
7X Ø 0.125 (3.18)
4X Ø 0.110 (2.79)

©National Instruments Corporation 3 NI USB-6221/6229/6251/6259 OEM User Guide
Figure 3 shows the dimensions of the USB-6229/6259 OEM device.
Figure 3. USB-6229/6259 OEM Dimensions in Inches (Millimeters)
0.436 (11.07)
0.392 (9.96)
0.362 (9.19)
0.162 (4.11)
0.062 (1.57)
0.000 (0.00)
0.396 (10.06)
0.304 (7.72)
0.256 (6.50)
0.116 (2.95)
0.000 (0.00)
6.950 (176.53)
4x 6.718 (170.63)
6.270 (159.26)
6.140 (155.96)
5.930 (150.62)
5.839 (148.31)
5.499 (139.67)
0.000 (0.00)
0.200 (5.08)
2.072 (52.63) 3.296 (83.72)
4.780 (121.41) 6.200 (157.48)
6.400 (162.56)
0.393 (9.98) 0.200 (5.08)
0.918 (23.32) 4.110 (104.39) 3.734 (94.84) 3.730 (94.74) 3.180 (80.77) 3.220 (81.79) 3.198 (81.22) 6.013 (152.74) 5.900 (149.86) 5.210 (132.33) 0.390 (9.91)
1.057 (26.85) 1.750 (44.45) 2.300 (58.42) 2.606 (66.19) 3.080 (78.23)
0.200 (5.08)
2.535 (64.39)
5.080 (129.03)
5.290 (134.37)
5.760 (146.30)
6.140 (155.96)
0.304 (7.72)
0.515 (13.08)
2X Ø 0.140 Cutout
in Panel for LEDs
Ø 0.330 Cutout in Panel
for Power Connector
2X Ø 0.156 (3.96)
7X Ø 0.125 (3.18)
4X Ø 0.110 (2.79)

NI USB-6221/6229/6251/6259 OEM User Guide 4 ni.com
I/O Connector Pinouts
Figures 4 through 7 show the connector pinouts for the USB-6221 OEM,
USB-6229 OEM, USB-6251 OEM, and USB-6259 OEM devices.
Refer to the M Series User Manual at ni.com/manuals for more
information about USB-6221/6229/6251/6259 signals and how to
connect them.

©National Instruments Corporation 5 NI USB-6221/6229/6251/6259 OEM User Guide
Figure 4. USB-6221 OEM Connector Pinout
AO 0
AO 1
AI GND
AI GND
AI GND
AI 8
AI 1
AI GND
AI 10
AI 3
AI GND
AI 12
AI 5
AI GND
AI 14
AI 7
AI GND
AO GND
AO GND
NC
AI 0
AI GND
AI 9
AI 2
AO GND
AI SENSE
AI GND
AI 11
AI 4
AI GND
AI 13
AI 6
AI GND
AI 15
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
P0.0
P0.1
P0.2
P0.3
P0.4
P0.5
P0.6
P0.7
PFI 0
PFI 1
PFI 2
PFI 3
PFI 4
PFI 5
PFI 6
PFI 7
PFI 8
PFI 9
PFI 10
PFI 11
PFI 12
PFI 13
PFI 14
PFI 15
+5 V
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
+5 V
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
36
38
40
42
44
46
48
50
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
35
37
39
41
43
45
47
49
Bank 0
Bank 0
50-Pin Digital Connector
34-Pin Analog Connector
NC = No Connect

NI USB-6221/6229/6251/6259 OEM User Guide 6 ni.com
Figure 5. USB-6229 OEM Connector Pinout
AO 0
AO 1
AI GND
AI GND
AI GND
AI 8
AI 1
AI GND
AI 10
AI 3
AI GND
AI 12
AI 5
AI GND
AI 14
AI 7
AI GND
AO GND
AO GND
NC
AI 0
AI GND
AI 9
AI 2
AO GND
AI SENSE
AI GND
AI 11
AI 4
AI GND
AI 13
AI 6
AI GND
AI 15
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
AO 2
AO 3
AI GND
AI GND
AI GND
AI 24
AI 17
AI GND
AI 26
AI 19
AI GND
AI 28
AI 21
AI GND
AI 30
AI 23
AI GND
AO GND
AO GND
NC
AI 16
AI GND
AI 25
AI 18
AO GND
AI SENSE 2
AI GND
AI 27
AI 20
AI GND
AI 29
AI 22
AI GND
AI 31
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
P0.0
P0.1
P0.2
P0.3
P0.4
P0.5
P0.6
P0.7
PFI 0
PFI 1
PFI 2
PFI 3
PFI 4
PFI 5
PFI 6
PFI 7
PFI 8
PFI 9
PFI 10
PFI 11
PFI 12
PFI 13
PFI 14
PFI 15
+5 V
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
+5 V
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
36
38
40
42
44
46
48
50
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
35
37
39
41
43
45
47
49
P0.8
P0.9
P0.10
P0.11
P0.12
P0.13
P0.14
P0.15
P0.16
P0.17
P0.18
P0.19
P0.20
P0.21
P0.22
P0.23
P0.24
P0.25
P0.26
P0.27
P0.28
P0.29
P0.30
P0.31
+5 V
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
+5 V
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
36
38
40
42
44
46
48
50
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
35
37
39
41
43
45
47
49
Bank 0
Bank 0
50-Pin Digital Connectors
34-Pin Analog Connectors
Bank 1
Bank 1
NC = No Connect NC = No Connect

©National Instruments Corporation 7 NI USB-6221/6229/6251/6259 OEM User Guide
Figure 6. USB-6251 OEM Connector Pinout
AO 0
AO 1
AI GND
AI GND
AI GND
AI 8
AI 1
AI GND
AI 10
AI 3
AI GND
AI 12
AI 5
AI GND
AI 14
AI 7
AI GND
AO GND
AO GND
APFI 0
AI 0
AI GND
AI 9
AI 2
AO GND
AI SENSE
AI GND
AI 11
AI 4
AI GND
AI 13
AI 6
AI GND
AI 15
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
P0.0
P0.1
P0.2
P0.3
P0.4
P0.5
P0.6
P0.7
PFI 0
PFI 1
PFI 2
PFI 3
PFI 4
PFI 5
PFI 6
PFI 7
PFI 8
PFI 9
PFI 10
PFI 11
PFI 12
PFI 13
PFI 14
PFI 15
+5 V
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
+5 V
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
36
38
40
42
44
46
48
50
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
35
37
39
41
43
45
47
49
Bank 0
Bank 0
50-Pin Digital Connector
34-Pin Analog Connector

NI USB-6221/6229/6251/6259 OEM User Guide 8 ni.com
Figure 7. USB-6259 OEM Connector Pinout
AO 0
AO 1
AI GND
AI GND
AI GND
AI 8
AI 1
AI GND
AI 10
AI 3
AI GND
AI 12
AI 5
AI GND
AI 14
AI 7
AI GND
AO GND
AO GND
APFI 0
AI 0
AI GND
AI 9
AI 2
AO GND
AI SENSE
AI GND
AI 11
AI 4
AI GND
AI 13
AI 6
AI GND
AI 15
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
AO 2
AO 3
AI GND
AI GND
AI GND
AI 24
AI 17
AI GND
AI 26
AI 19
AI GND
AI 28
AI 21
AI GND
AI 30
AI 23
AI GND
AO GND
AO GND
APFI 1
AI 16
AI GND
AI 25
AI 18
AO GND
AI SENSE 2
AI GND
AI 27
AI 20
AI GND
AI 29
AI 22
AI GND
AI 31
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
P0.0
P0.1
P0.2
P0.3
P0.4
P0.5
P0.6
P0.7
PFI 0
PFI 1
PFI 2
PFI 3
PFI 4
PFI 5
PFI 6
PFI 7
PFI 8
PFI 9
PFI 10
PFI 11
PFI 12
PFI 13
PFI 14
PFI 15
+5 V
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
+5 V
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
36
38
40
42
44
46
48
50
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
35
37
39
41
43
45
47
49
P0.8
P0.9
P0.10
P0.11
P0.12
P0.13
P0.14
P0.15
P0.16
P0.17
P0.18
P0.19
P0.20
P0.21
P0.22
P0.23
P0.24
P0.25
P0.26
P0.27
P0.28
P0.29
P0.30
P0.31
+5 V
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
+5 V
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
36
38
40
42
44
46
48
50
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
35
37
39
41
43
45
47
49
Bank 0
Bank 0
50-Pin Digital Connectors
34-Pin Analog Connectors
Bank 1
Bank 1

©National Instruments Corporation 9 NI USB-6221/6229/6251/6259 OEM User Guide
LEDs
USB-6221/6229/6251/6259 OEM devices have two LEDs that reflect
the device state. The green READY LED indicates whether the device is
powered on and configured as a USB device. The yellow ACTIVE LED
indicates whether there is USB bus activity.
Three connectors on the device allow you to connect an external LED
circuit to the device. To connect an external READY LED, use E1 as the
positive connection (+3.3 V) and E2 as the negative connection. To connect
an external ACTIVE LED, use E1 as the positive connection and E3 as the
negative connection. E1 is current limited with a 100 Ωresistor to the 3.3 V
internal supply. This configuration limits the current to approximately
16 mA into a single external LED or approximately 8 mA each when both
LEDs are on. You also can limit this current further by using external
resistors as shown in Figure 8.
Figure 8. USB-6221/6229/6251/6259 OEM LEDs
Figure 9 shows how to connect an external READY or ACTIVE LED
circuit to the device.
Figure 9. Schematics of the USB-6221/6229/6251/6259 OEM LEDs
DS1
E3 E2 E1
E1
100 Ω
Internal
3.3 V
External
READY LED
External
ACTIVE LED
E2
External Resistor
E3
External Resistor

NI USB-6221/6229/6251/6259 OEM User Guide 10 ni.com
Power Switch
The power switch on the USB-6221/6229/6251/6259 OEM device powers
the device on and off. Figure 10 shows the pins on the power switch.
Figure 10. Power Switch (USB-6229/6259 OEM Shown)
Pin 1 is connected to VDC through the fuse (reference designator XF1).
The VDC is the voltage provided by the power supply through the power
connector (reference designator J4) and must be 11–30 V, 20 W.
Pin 2 provides power to the circuitry on the USB-6221/6229/6251/6259
OEM device. When the switch is in the On position, the VDC power supply
from pin 1 is routed to pin 2.
Pin 3 connects pin 2 to ground through a 100 kΩresistor when the switch
is in the Off position. This allows the internal power supply in the
USB-6221/6229/6251/6259 OEM device to safely discharge to ground
when it is powered off. Figure 11 shows a schematic of the switch.
Figure 11. Schematic of the USB-6221/6229/6251/6259 OEM Switch
J4
Provides
Power to
Device
VDC Comes
from Fuse
XF1
Switch
123
45
100 kΩ
SW1
Outer
Shell
SW1 XF1
FUSE
3
Power to
Device
J4
Power
Connector
1
2
100 kΩ