NuAire Labgard NU-430-400 Manual

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LabgardESEnergySaverClassII,
TypeB2LaminarFlow
BiologicalSafetyCabinet
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Models
NU‐430‐400/600
Bench/Console
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Operation&MaintenanceManual
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February,2014
(Series65)
Revision1
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 
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ManufacturedBy:
NuAire,Inc.
2100FernbrookLane
Plymouth,MN55447
Toll‐Free:1‐800‐328‐3352
InMinnesota:(763)‐553‐1270
Fax:(763)‐553‐0459

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February/2014
Congratulations!
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YouhavejustpurchasedoneofthefinestLaminarFlowBiologicalSafetyCabinetsavailable.Withpropercare,
maintenance(certification),andlaboratoryprocedure,thiscabinetwillgiveyouyearsofproductandpersonnelprotectionfrom
particulatecontaminantsasprescribedinNSF/ANSI49.Pleasereadthismanualcarefullytofamiliarizeyouwithproperinstallation,
maintenanceandoperationofthecabinet.Otherreferenceandguidelinematerialsareavailablethroughthefollowingwebsites.
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www.hc‐sc.gc.ca
www.cdc.gov/od/ohs/
www.absa.org
www.absa‐canada.org
www.ebsa.be
www.inspection.gc.ca
www.who.int
www.biosafety.be
www.hse.gov.uk
www.nsf.org
www.cetainternational.org
www.osha.gov/dts/osta/
www.nuaire.com

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ABOUTTHISOPERATION&MAINTENANCEMANUAL
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Theinformationcontainedinthismanualisintendedtoreflectourcurrentproductionstandardconfigurationmodelalong
withthemorefrequentlypurchasedoptions.Anyuniqueadditions/modifications/shopdrawingsareappendedinthebackflapof
thismanual,alongwithanymodificationsand/oradditionstoproceduresasoutlinedinthismanual.Acopyoftheoriginalfactory
testreportisalsoappendedtothismanual.Incasethismanualand/ortestreportislostormisplaced,NuAireretainsacopyinour
files.AreplacementcopycanbeobtainedbycallingorwritingNuAire,Inc.statingthemodelnumberandserialnumberandabrief
descriptionoftheinformationdesired.

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LabgardESEnergySaverClassII,TypeB2LaminarFlowBiologicalSafetyCabinet
ModelsNU‐430‐400/600Operation&MaintenanceManual
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TABLEOFCONTENTS
SectionNo.1...........................................................GeneralInformation
SectionNo.2...........................................................Models&Features
SectionNo.3...........................................................Warranty
SectionNo.4...........................................................Shipments
SectionNo.5...........................................................InstallationInstructions
 5.1.................................................................Location
 5.2.................................................................Set‐upInstructions
 5.3.................................................................Exhaust/SupplyAirChecks
 5.4.................................................................CertificationTestingMethodsandEquipment
SectionNo.6...........................................................OperatingtheNU‐430
 6.1.................................................................BiologicalSafetyCabinetControl
 6.2.................................................................OperatingGuidelines
 6.3.................................................................OperatingSequence
 6.4.................................................................Ergonomics
 6.5.................................................................CleaningProcedures
 6.6.................................................................HazardousDrugDecontaminationProcedure
SectionNo.7...........................................................GeneralMaintenance
 7.1.................................................................Decontamination
 7.2.................................................................FluorescentLampBulbReplacement
 7.3.................................................................HEPAFilter/MotorReplacement
 7.4.................................................................SlidingWindowReplacement&Adjustment
 7.5.................................................................AirflowControlSystemSetup&Calibration
 7.6.................................................................HEPAFilterLeakTest
 7.7.................................................................AirflowSmokePatternTest
 7.8.................................................................SiteInstallationAssessmentTests
 7.9.................................................................CleanlinessClassificationTestforPharmacyApplication
 7.10...............................................................MainControlBoardDescription&Replacement
 7.11...............................................................DigitalAirflowSensorDescription&Replacement
SectionNo.8...........................................................ErrorIndicators,Troubleshooting,Option‐Diagnostics&
AirflowSensorPerformanceVerification
SectionNo.9...........................................................RemoteContacts
SectionNo.10.........................................................OptionalEquipment
 10.1.................................................................UltravioletLight
SectionNo.11.........................................................Electrical/EnvironmentalRequirements
SectionNo.12.........................................................DisposalandRecycle
Insert..........................................................................ReplacementPartsList
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MANUALDRAWINGS
ACD‐12153....................................................NU‐430AirflowSchematic
BCD‐15501.....................................................NU‐430‐400SpecificationDrawing
BCD‐15502.....................................................NU‐430‐600SpecificationDrawing
BCD‐11815.....................................................DrainValveInstallation
BCD‐05572.....................................................ButterflyValveInstallation
BCD‐05660.....................................................BagIn/BagOutProcedure
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ASSEMBLYDRAWINGS
BCD‐05147.....................................................BaseStandAssembly
BCD‐05146.....................................................BaseStandStorageCabinetAssembly
BCD‐11817.....................................................ControlCenter&FrontDecorativePanelAssembly
BCD‐11818.....................................................SlidingWindowAssembly&Adjustment
BCD‐14185.....................................................BaseCabinetAssembly
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ELECTRICALSCHEMATICS
BCD‐16606(Sheets1‐2)................................NU‐430‐400/600ElectricalSchematic

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LabgardESEnergySaverClassII,
TypeB2LaminarFlow
BiologicalSafetyCabinet
Models
NU‐430‐400/600
MANUFACTUREDBY:
NuAire,Inc.‐Plymouth,Minnesota,U.S.A.
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1.0 GeneralInformation
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1.1Description
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TheLABGARDESModelNU‐430LaminarFlowBiologicalSafetyCabinet(LFBSC)isabench/tabletopmodel,optionally
availablewithabasesupportstand,foroperationasaconsolemodel.TheLABGARDESmodelNU‐430utilizesanEnergy
SaverDCECMmotoroptimallydeterminedforwardcurvedfanforeachmodelsize/widthtomaximizebothenergy
efficiencyandfilterloadingcapacity.TheEnergySaverECMmotoriscontrolledtoairflowsetpointsviaasolid‐stateDC
motorcontrollerwithdigitaldualthermistorairflowsensorsthatprovideanautomaticcompensation(constantvolume
control)forbothfilterloadingandlinevoltagevariances.
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TheLaminarFlowBiologicalSafetyCabinet,(LFBSC)isaproductresultingfromthedevelopmentofthe"laminarflow"
principleandtheapplicationofenvironmentalcontrolsasrequiredinthefieldofbiologicalresearchorchemical
containment.TheLFBSC,whenusedwithpropertechnique,isaneffectivelaboratoryaidinobtainingtheoptimumcontrol
overproductqualitywhilereducingthepotentialforexposureofbothproductandpersonneltoairbornebiologicalor
particulatechemicalagentsinlowtomoderaterisk‐hazardresearchanddrugpreparationorproductoperations,as
prescribedbytheCenterforDiseaseControl(CDC)Atlanta,Georgia.
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TheNU‐430BenchLFBSCmeetstherequirementsofaClassII,TypeB2sincethecabinetconformstothefollowing
requirements:

-Maintainaminimumaverageinflowvelocityof100fpm(0.51m/s)throughtheworkaccessopening;

-HaveHEPAfiltereddownflowairdrawnfromthelaboratoryortheoutsideair(i.e.downflowairisnotre‐circulated
fromthecabinetexhaustair;
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-Exhaustallinflowanddownflowairtotheatmospherethroughahardconnectiontothefacilityexhaustsystemafter
filtrationthroughaHEPAfilterwithoutrecirculationinthecabinetorreturntothelaboratory;
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-Haveallcontaminatedductsandplenumsundernegativepressureorsurroundedbydirectlyexhausted
(non‐re‐circulatedthroughtheworkarea)negativepressureductsandplenums.
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TypeB2cabinetsmaybeusedforworkwithnonflammableorexplosivevolatilechemicalsandradionuclidesrequired
asadjunctstomicrobiologicalstudies.
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1.2SafetyInstructions
ThesesafetyinstructionsdescribethesafetyfeaturesoftheLABGARDESModelNU‐430LFBSC.
Thesafetycabinethasbeenmanufacturedusingthelatesttechnologicaldevelopmentsandhasbeenthoroughlytested
beforedelivery.However,thecabinetmaypresentpotentialhazardsifitisnotinstalledandusedasinstructedforits
intendedpurposeoroutsideofoperatingparameters.Therefore,thefollowingproceduresmustalwaysbeobserved:
Thesafetycabinetmustbeoperatedonlybytrainedandauthorizedpersonnel.
Foranyoperationofthiscabinet,theoperatormustprepareclearandconcisewritteninstructionsforoperating
andcleaning,utilizingapplicablesafetydatasheets,planthygieneguidelines,andtechnicalregulations,in
particular.
oWhichdecontaminationmeasuresaretobeappliedforthecabinetandaccessories?
oWhichprotectivemeasuresapplywhilespecificagentsareused?
oWhichmeasuresaretobetakeninthecaseofanaccident?
Repairstothedevicemustbecarriedoutonlybytrainedandauthorizedexpertpersonnel.
Keeptheseoperatinginstructionsclosetothecabinetsothatsafetyinstructionsandimportantinformationare
alwaysaccessible.
Shouldyouencounterproblemsthatarenotdetailedadequatelyintheoperatinginstructions,pleasecontactyour
NuAireRepresentativeofNuAiretechnicalServices.
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1.3ExplanationofSymbols
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NOTE:
CAUTION used without the safety alert symbol
indicates a potentially hazardous situation which, if
not avoided, may result in property damage.
Potential electrical hazard, only qualified person
to access.
Used for important information.
Biohazard
Ground, Earth
CAUTION

Lead Free Chemical Hazard
Flammable Hazard
Hazardous Gases! Personal
Protection Equipment
Re
q
uired.
Safety alert symbol indicates a potentially hazardous
situation which, if not avoided, could result in death
of serious injury.
Safety alert symbol indicates a potentially hazardous
situation which, if not avoided, may result in minor or
moderate injury.
WARNING
!
CAUTION
!

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2.0Models&Features
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ThemodelNU‐430,LABGARDESClassII,TypeB2LaminarFlowBiologicalSafetyCabinetismanufacturedintwosizes:
4ft.(1.2m)and6ft.(1.8m).
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OM0228Page9of99
February/2014

OM0228Page10of99
February/2014
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