Buchi B-290 User manual

B-290 Mini Spray Dryer
Operation Manual
093001M en

Imprint
Product Identification:
Operation Manual (Original), Mini Spray Dryer B-290
093001M en
Publication date: 03.2018
BÜCHI Labortechnik AG
Meierseggstrasse 40
Postfach
CH-9230 Flawil 1
E-Mail: [e-mail]
BUCHI reserves the right to make changes to the manual as deemed necessary in the light of experience; espe-
cially in respect to structure, illustrations and technical detail.
This manual is copyright. Information from it may not be reproduced, distributed, or used for competitive purpos-
es, nor made available to third parties. The manufacture of any component with the aid of this manual without
prior written agreement is also prohibited.

Table of contents
3
B-290 Operation Manual, Version M
Table of contents
1 About this manual . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .6
2 Safety. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .7
2.1 User qualification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
2.2 Proper use . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7
2.3 Improper use . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8
2.4 Safety warnings and safety signs used in this manual . . . . . . . . . . . . . . . . . . 8
2.5 Product safety. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
2.5.1 General hazards. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10
2.5.2 Warning labels on housing and assemblies . . . . . . . . . . . . . . . . . . . . . . 14
2.5.3 Personal protective equipment . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14
2.5.4 Safety elements and measures . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
2.6 General safety rules . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16
3 Technical data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
3.1 Scope of application and delivery . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
3.1.1 Standard instrument. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
3.1.2 Standard accessories . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18
3.1.3 Standard accessories with the B-290 Advanced . . . . . . . . . . . . . . . . . . . 18
3.1.4 Standard accessories with the B-290 Acid resistant. . . . . . . . . . . . . . . . . . 18
3.1.5 Optional accessories . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19
3.2 Technical data overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20
3.3 Materials used. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21
4 Description of function . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22
4.1 Functional principle of the drying gas . . . . . . . . . . . . . . . . . . . . . . . . . 22
4.2 Functional principle of the sample feed and dispersion . . . . . . . . . . . . . . . . 22
4.3 Outlet filter. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
4.4 Inert Loop B-295 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23
4.5 Dehumidifier B-296 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 24
4.6 Spray chilling accessory . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25
4.7 Connected accessories to the Mini Spray Dryer B-290 . . . . . . . . . . . . . . . . 25
4.7.1 Feed switch valve and remote control panel . . . . . . . . . . . . . . . . . . . . . . 26
4.7.2 Printer or PC for data output via RS-232 serial port . . . . . . . . . . . . . . . . . . 26
5 Putting into operation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27
5.1 Installation site. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27
5.2 Electrical connections . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27
5.3 Installing the compressed air maintenance unit and compressor (optional) . . . . . . 29
5.4 Installing the glass assembly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30
5.5 Installing the spraying nozzle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31
5.6 Installing the filters. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32
5.6.1 Inlet filter installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33
5.6.2 Outlet filter installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33
5.6.3 PTFE filter membrane installation . . . . . . . . . . . . . . . . . . . . . . . . . . . 34
5.6.4 Cleaning filter installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36
5.7 Adjusting the peristaltic pump bed and choosing the feeding tube . . . . . . . . . . 36
5.8 Tubing installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38
5.9 Installing the compressor . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39
5.10 Quick hose couplings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40

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5.11 Installing the Inert Loop B-295 . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40
5.12 Dehumidifier B-296 and Inert Loop B-295 combination . . . . . . . . . . . . . . . . 43
5.13 Installing the Dehumidifier B-296 . . . . . . . . . . . . . . . . . . . . . . . . . . . 43
5.14 Installing the Spray Chilling Accessory. . . . . . . . . . . . . . . . . . . . . . . . . 45
5.15 Installation check . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 46
6 Operation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47
6.1 Layout of the operating and display elements . . . . . . . . . . . . . . . . . . . . . 48
6.2 Conversion tables for the parameters . . . . . . . . . . . . . . . . . . . . . . . . . 49
6.2.1 Flow meter spraying air (rotameter) . . . . . . . . . . . . . . . . . . . . . . . . . . 49
6.2.2 Peristaltic pump . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49
6.2.3 Aspirator . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50
6.3 Spray process. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50
6.4 Optimizing parameters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51
6.5 End of spray process . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51
6.6 Recovering particles of the outlet filter . . . . . . . . . . . . . . . . . . . . . . . . . 52
6.7 Operation with the Inert Loop B-295 . . . . . . . . . . . . . . . . . . . . . . . . . 53
6.7.1 Status messages . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54
6.8 Operation with the Spray Chilling Accessory. . . . . . . . . . . . . . . . . . . . . . 55
6.9 Mini Spray Dryer B-290 acid resistant . . . . . . . . . . . . . . . . . . . . . . . . . 56
7 Maintenance and repairs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57
7.1 Housing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58
7.2 Glass assembly, tubes. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58
7.3 Nozzles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58
7.4 Aspirator cleaning . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59
7.5 Inert Loop B-295 and Dehumidifier B-296. . . . . . . . . . . . . . . . . . . . . . . 59
7.6 Outlet filter. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 60
7.7 Calibrating the oxygen sensor of the Inert Loop B-295 . . . . . . . . . . . . . . . . 60
7.8 Replacing the oxygen sensor of the Inert Loop B-295 . . . . . . . . . . . . . . . . . 61
7.9 Spray chilling accessory . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61
7.10 Customer service . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61
8 Troubleshooting . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62
8.1 Error messages and their remedy . . . . . . . . . . . . . . . . . . . . . . . . . . . 62
8.2 Malfunctions and their remedy. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63
9 Shutdown, storage, transport and disposal . . . . . . . . . . . . . . . . . . . . . . . . 65
9.1 Storage and transport . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 65
9.2 Disposal. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 65
10 Spare parts. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66
10.1 Spray nozzle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 66
10.2 Glass parts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70
10.3 Filters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72
10.4 Tubings and connectors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 72
10.5 Trolley . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73
10.6 Measurement pipe for gas flow . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73
10.7 Feed switch valve . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74
10.8 Remote control panel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74
10.9 Inert Loop B-295 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74
10.10 Cylinder insulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75
10.11 Spray chilling accessory . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76
10.12 Pre-cleaning glass-set and sterile filter. . . . . . . . . . . . . . . . . . . . . . . . . 77
10.13 Acid resistant accessories. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78

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11 Declarations and requirements. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79
11.1 FCC requirements (for USA and Canada) . . . . . . . . . . . . . . . . . . . . . . . 79
11.2 Safety certificate. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 80

1 About this manual
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B-290 Operation Manual, Version M
1 About this manual
This manual describes the Mini Spray Dryer B-290 and its optional accessories and provides all infor-
mation required for its safe operation and to maintain it in good working order.
It is addressed to laboratory personnel and operators in particular.
Read this manual carefully before installing and running your system and note the safety precautions
in chapter 2 in particular. Store the manual in the immediate vicinity of the instrument, so that it can be
consulted at any time.
No technical modifications may be made to the instrument without the prior written agreement of
BUCHI. Unauthorized modifications may affect the system safety or result in accidents. Technical data
are subject to change without notice.
NOTE
The symbols pertaining to safety are explained in chapter 2.
This manual is copyright. Information from it may not be reproduced, distributed or used for competi-
tive purposes, nor made available to third parties. The manufacture of any component with the aid of
this manual without prior written agreement is also prohibited.
The English manual is the original language version and serves as basis for all translations into other
languages. If you need another language version of this manual, you can download other versions at
www.buchi.com or reorder manuals from a BUCHI representative.
Abbreviations
EPDM: Ethylene Propylene Dimonomer
FFKM: Perfluoroelastomers
FPM: Fluoroelastomer
PEEK: Polyetheretherketone
PTFE: Polytetrafluoroethylene
POM: Polyoxymethylene
PFA: Perfluoroalkoxy

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B-290 Operation Manual, Version M
2 Safety
This chapter highlights out the safety concept of the instrument and contains general rules of behavior
and warnings from direct and indirect hazards concerning the use of the product.
For the users safety, all safety instructions and safety messages in the individual sections shall
be strictly observed and followed. Therefore, the manual must always be available to all persons
performing any tasks described herein.
2.1 User qualification
The instrument is designed and built in accordance with state-of-the-art technology. Nevertheless, risks
to users, property, and the environment can arise when the instrument is used carelessly or improperly.
The manufacturer has determined residual dangers emanating from the instrument
• if the instrument is operated by insufficiently trained personnel without supervision.
• if the instrument is not operated according to its proper use.
Appropriate warnings in this manual serve to make the user alert to these residual hazards.
Personnel without this training or persons who are currently being trained require careful instruction.
The present Operation Manual serves as the basis for this.
2.2 Proper use
The Mini Spray Dryer B-290 has been designed and built as laboratory instrument and for batch
production. It serves to spray-dry aqueous solutions or suspensions in one operating process.
In combination with the Inert Loop B-295, it is possible to work with organic solvents in “closed
mode”. Processing in “closed mode” requires N2as an inert gas.
The output particle size of the Mini Spray Dryer B-290 is between 2–25 µm. Thus, the instrument is
suited to generate particles in the inhalable size range from a solution of suspension.
• If the instrument is used with potentially toxic or hazardous substances in ‘open mode’, it has
to be installed inside a closed fume hood or glove box. In such cases, the complete processing
and system handling has to be performed within the ventilated box to avoid toxication and other
hazardous situations to the user and the environment.
• Spray drying of corrosive samples require handling in a closed fume hood. An acid proof system in
open loop is a variant of the Mini Spray Dryer B-290.
• In any case, all exhausts leaving the exhaust gas tubing have to be lead away instantly by a ventila-
tion system, to remove possibly hazardous substances and fumes from the working area. The
ventilation system has to be equipped with safety measures such as outlet filters to avoid contami-
nation of the environmen.
• Operation and handling can require additional personal protective equipment. Operate the instru-
ment with respect to standard laboratory safety rules (i.e. as stated in the latest version of the WHO
“Laboratory biosafety manual”) at all times.
• If the Mini Spray Dryer B-290 is used in combination with other instruments (e.g. Chiller) all related
manuals are to be fully observed.
• Electrostatic charges are to be arrested from both the product collection vessel and the cyclone via
the standard grounding cable if the cyclone is equipped with a grounding socket.
• If the instrument is used for food, pharma and cosmetic products additional cleaning measures are
required.

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2.3 Improper use
Applications not mentioned in section 2.2 are considered to be improper. Also, applications which do
not comply with the technical data (see section 3 of this manual) are considered to be improper. The
operator bears the sole risk for any damages or hazards caused by such improper use.
The following uses are expressly forbidden:
• Use of gases with unknown chemical composition.
• Spray drying of biohazardous materials such as viruses or bacteria.
• Spray drying of organic solvents without safety lamella curtain, Inert Loop B-295 and in open mode.
• Use of the instrument in rooms which require ex-protected instruments.
• Spray drying of substances which might explode or ignite due to the processing and the selected
parameters of the Mini Spray Dryer B-290 or installed sub systems.
• Spray drying of toxic substances.
• Use of samples which might produce oxygen during the processing.
• Unattended use.
2.4 Safety warnings and safety signs used in this manual
DANGER, WARNING, CAUTION and NOTICE are standardized signal words for identifying levels of
hazards and risks related to personal injury and property damage. All signal words, which are related
to personal injury are accompanied by the general safety sign.
For your safety it is important to read and fully understand the table below with the different signal
words and their definitions!
Sign Signal word Definition Risk level
DANGER Indicates a hazardous situation which, if not avoided, will
result in death or serious injury. ★★★★
WARNING Indicates a hazardous situation which, if not avoided, could
result in death or serious injury. ★★★☆
CAUTION Indicates a hazardous situation which, if not avoided, may
result in minor or moderate injury. ★★☆☆
no NOTICE Indicates possible property damage, but no practices
related to personal injury.
★☆☆☆
(property damage only)
Supplementary safety information symbols may be placed in a rectangular panel on the left to the
signal word and the supplementary text (see example below).
Space for
supplementary
safety
information
symbols.
!SIGNAL WORD
Supplementary text, describing the kind and level of hazard/risk seriousness.
• List of measures to avoid the herein described, hazard or hazardous situation.
• ...
• ...

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B-290 Operation Manual, Version M
Table of supplementary safety information symbols
The reference list below incorporates all safety information symbols used in this manual and their
meaning.
Symbol Meaning
General warning
Electrical hazard
Heavy weight, avoid over exertion
Explosive gases, explosive environment
Harmful to life-forms
Hot item, hot surface
Device damage
Inhalation of substances
Chemical burns by corrosives
Fragile components
Wear laboratory coat

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Wear protective goggles
Wear protective mask
Wear protective gloves
Additional user information
Paragraphs starting with NOTE transport helpful information for working with the device/software or its
supplementaries. NOTEs are not related to any kind of hazard or damage (see following example).
NOTE
Useful tips for the easy operation of the instrument/software.
2.5 Product safety
Safety warnings in this manual (as described in section 2.4) serve to make the user alert and to avoid
hazardous situations emanating from residual dangers by giving appropriate counter measures.
However, risks to users, property and the environment can arise when the instrument is damaged,
used carelessly or improperly.
2.5.1 General hazards
The following safety messages show hazards of general kind which may occur when handling the
instrument. The user shall observe all listed counter measures in order to achieve and maintain the
lowest possible level of hazard.
Additional warning messages can be found whenever actions and situations described in this manual
are related to situational hazards.
!DANGER
Death by suffocation or serious poisoning by inhalation of inert gases.
• Do not inhale inert gases
• Directly withdraw released gases and gaeous substances by sufficient ventilation
• Only operate the instrument in ventilated environments
• Before opertation, check all parts, connections and sealings involved in the gasflow for proper
sealing
• Exchange worn out or defective parts immediately

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!DANGER
Death or serious poisoning by gases or particles due to O2- sensonr or filter malfunction
• Exchange defective O2-sensor immediately
• Exchange O2-sensor regularly within the specified maintenance intervals
• Exchange clogged filters immediately
• Exchange filters regularly within the specified maintenance intervals
• Dispose of filter immediately
!DANGER
Death or serious poisoning by inhalation or incorporation of dried particles during spray process.
• Wear safety goggles
• Wear safety gloves
• Wear a suitable protective mask
• Wear a laboratory coat
• Check for proper sealing before use
• Do not inhale dried particles
• Stop drying gas flow before opening the drying circuit

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!DANGER
Death or serious posioning by inhalation or incorporation of dried particles at recovery.
• Wear safety goggles
• Wear safety gloves
• Wear a suitable protective mask
• Wear a laboratory coat
• Do not inhale dried particles
• Stop drying gas flow before opening the drying circuit
• Only recover particles in sufficiently ventilated flue or glove-box
• Do not disperse the dried particles
• Do not clean dusty parts with compressed air
!WARNING
Death or serious injuries by use in explosive environments.
• Do not operate the instrument in explosive environments
• Do not operate the instrument with explosive gas mixtures
• Before operation, check all gas connections for correct installation
• Directly withdraw released gases and gaseous substances by sufficient ventilation

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!WARNING
Death or serious poisoning by contact or incorporation of harmful substances at use.
• Before operation, check the instrument for correct assembling
• Before operation, inspect sealings and tubes for good condition
• Exchange worn out or defective parts immediately
• Exchange clogged filters immediately
• Only operate the instrument in ventilated environments
• Directly withdraw released gases and gaseous substances by sufficient ventilation
• Perform a dry-run without sample material and check for gas leakages
!CAUTION
Risk of minor poisoning by inhalation of ozone.
• Directly withdraw released gases and gaseous substances by sufficient ventilation
!CAUTION
Risk of minor or moderate burnings when handling hot parts.
• Do not touch hot parts
• Let the system cool down for some minutes after use
!NOTICE
Risk of instrument short-circuits and damage by liquids.
• Do not spill liquids over the instrument or its component parts
• Wipe off any liquids instantly
• Place the sample vessel onto the designated reservoir-plate on top of the instrument
• Ensure a safe positioning of the sample vessel
• Do not move the instrument when it is loaded with liquid
• Keep external vibrations away from the instrument
!NOTICE
Risk of instrument damage by internal overpressure.
• External supply pressure must meet the system specifications
• Exchange clogged filters immediately
• Dispose of filter immediately

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!NOTICE
Risk of instrument damage by wrong mains supply.
• External mains supply must meet the voltage given on the type plate
• Check for sufficient grounding
2.5.2 Warning labels on housing and assemblies
The following warning sticker(s) can be found on the housing or assemblies of the Mini Spray Dryer
B-290 and Inert Loop B-295:
Symbol Meaning Location
Do not touch
hot item, hot
surface!
Label, located at the spray cylinder,
B-290
See text Sticker at the rear side, B-290
See text Sticker/label, located on the B-295
2.5.3 Personal protective equipment
Always wear personal protective equipment such as protective eye goggles, protective clothing and
gloves. Wear protective mask to protect from inhalation of fine particles. The personal protective
equipment must meet all requirements of all data sheets for the chemicals used. These instructions
are an important part of the instrument and must be made available at all times to the operating
personnel at the place where the equipment is deployed. Additional protective measures can
be necessary according to the applications! The user is fully responsible for choosing adequate
measures!

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!WARNING
Serious chemical burns by corrosives.
• Observe all data sheets of the used chemicals
• Handle corrosives in well ventilated environments only
• Always wear protective goggles
• Always wear protective gloves
• Always wear protective clothes
• Do not use damaged glassware
• Wear protective mask when working with inhalable particles
2.5.4 Safety elements and measures
To arrest electrostatic charges from the instrument, it is internally grounded. Electrostatic charges are
to be arrested from both the product collection vessel via the external (yellow) grounding cable for all
cyclones with grounding socket.
Heating
• Excess temperature protection against uncontrolled overheating.
• Automatic temperature control of the heater and inlet temperature.
• Heater can not be started before the closed loop is inert
Spraying (Pump)
• Pump can not be started before the closed loop is inert
Air/Gas
The system can be used in suction mode (standard) or in pressure mode. The suction procedure used
in the Mini Spray Dryer B-290 produces a light negative pressure in the instrument and thus rules out,
together with the inlet filter and outlet filter, a contamination of the environment through leaking from
the instrumen.
Automatic processing interruption when system pressure is too low in closed mode
• Outlet filter to protect the environment contamination of fine dust particles via exhaust gas tubing
N2 inert gas
The Mini Spray Dryer B-290 Advanced can be used to work with organic solvent in combination with
the Inert Loop B-295.
• Inertization against explosive gas mixtures
• oxygen concentration measurement (inside the Inert Loop B-295)
• pressure measurement (inside the Inert Loop B-295)
The heater and the pump stop if the oxygen level is > 6 vol.% or if the pressure level is < 10 mbar.

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Glass
• Use of inert 3.3 borosilicate glass.
• Grounded coating of the inner surface of the cyclone to prevent any electrostatic charge of the
power.
• Screw couplings between glass connections to prevent glass breakage.
Optional system configuration with Inert Loop B-295
• Overpressure leakage detection.
• Safe gas condition (< 6 % O2content) is detected and enables the regulation of the drying gas
mixture via a communication cable.
2.6 General safety rules
Responsibility of the operator
The head of the laboratory is responsible for training his/her personne.
The operator shall inform the manufacturer without delay of any safety-related incidents which might
occur during operation of the instrument or its accessories. Legal regulations, such as local, state and
federal laws applying to the instrument or its accessories must be strictly followed.
Duty of maintenance and care
The operator is responsible for the proper condition of instrument. This includes maintenance, service
and repair jobs that are performed and on schedule by authorized personnel only.
Spare parts to be used
Use only genuine consumables and spare parts for maintenance to assure good system performance,
reliability and safety. Any modifications of spare parts or assemblies are only allowed with the prior
written permission of the manufacturer.
Modifications
Modifications to the instrument are only permitted after prior consultation and with the written approval
of the manufacturer. Modifications and upgrades shall only be carried out by an authorized BUCHI
technical engineer. The manufacturer will decline any claim resulting from unauthorized modifications.

3 Technical data
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B-290 Operation Manual, Version M
3 Technical data
This chapter introduces the reader to the instrument specifications. It contains the scope of delivery,
technical data, requirements and performance data.
3.1 Scope of application and delivery
The Mini Spray Dryer B-290 is available in three different set-ups:
Mini Spray Dryer B-290 Basic
• For aqueous applications with air in ‘open mode’
Mini Spray Dryer B-290 Acid resistant
• For acidic applications with air in ‘open mode’
Mini Spray Dryer B-290 Advanced
• For solvent applications in combination with Inert Loop B-295
• Optional use with Dehumidifier B-296
• Accessories are solvent resistant
The scope of delivery can only be checked according to the individual delivery note and the listed
order numbers.
NOTE
For additional information on the listed products, see www.buchi.com or contact your local dealer.
3.1.1 Standard instrument
Table 3-1: Standard instrument
Product Order number
Mini Spray Dryer B-290 200 V 44781
Mini Spray Dryer B-290 230 V 44780
Mini Spray Dryer B-290 Advanced 200 V 44700
Mini Spray Dryer B-290 Advanced 230 V 44699
Mini Spray Dryer B-290
Acid resistant 200 V
11056420
Mini Spray Dryer B-290
Acid resistant 230 V
11056421

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B-290 Operation Manual, Version M
3.1.2 Standard accessories
Table 3-2: Standard accessories
Product Order number
Operation Manual:
German 093000
English 093001
French 093002
Italian 093003
Spanish 093004
Glass assembly complete 044680
Compressed gas tube, 5 m with quick
coupling, complete 046356
Silicone tube for nozzle cooling, 4 m 004139
Silicone tube (per m) 004138
Cleaning brush for nozzle 044782
Polypress tube for gas stream, 3 m 046341
Hose clamps 004236
Spray Dryer Application Support and
Training (1 day training and application
tests)
910040
3.1.3 Standard accessories with the B-290 Advanced
Table 3-3: Standard accessories with the B-290
Advanced
Product Order number
Lamella safety curtain 044783
Feed switch valve 044725
Spray cylinder, vertical outlet 044697
Nozzle cap, 1.4 mm 044649
Tygon tube MH 2075 transparent (per m) 046314
Tygon tube F 4040 A yellow (per m) 046315
3.1.4 Standard accessories with the B-290 Acid resistant
Table 3-4: Standard accessories with the B-290
Acid resistant
Product Order number
Two-fluid nozzle acid resistant 11056320
Glass assembly acid resistant complete 11056386
Spray cylinder holder PFA coated 11056324
Cyclone metall cover PFA coated 11056327
Knurled screws PFA coated 11056325
Flange coupling PFA coated 11056326
Temperature sensor acid resistant 11056329

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B-290 Operation Manual, Version M
Table 3-4: Standard accessories with the B-290
Acid resistant (cont.)
Temperature sensor support adapter 11056318
Clamp ring ID 8 mm 11056387
O-ring FPM 8×1 mm 004221
Connecting nipple PFA coated 11056328
Connecting piece PFA coated 11056334
Needle 0.7 mm titanium 11056415
Nozzle tip 0.7 mm titanium 11056317
3.1.5 Optional accessories
Table 3-5: Optional accessories
Product Order number
Inert Loop B-295 50 Hz, 200 V 044779
Inert Loop B-295 50 Hz, 230 V 044701
Inert Loop B-295 60 Hz, 200 V 046345
Inert Loop B-295 60 Hz, 230 V 046344
Dehumidifier B-296 50/60 Hz, 230 V 040188
Dehumidifier B-296 50/60 Hz, 200 V 040181
Spray chilling accessory 50/60 Hz, 230 V 040351
Spray chilling accessory 50/60 Hz, 200 V 040352
Brown glass assembly 044758
Two-fluid nozzle, complete 044698
Three-fluid nozzle, complete 046555
Three-fluid nozzle conversion kit 046556
Three-fluid nozzle acid resistant 11056971
Cylinder Insulation 040058
Remote control panel B-290 044702
Outlet filter acid resistant complete 11056333
Outlet filter, complete 044754
Inlet filter 011235
Compressed air maintenance unit 004366
Oil-free compressor, 230 V/50 Hz 027907
Oil-free compressor, 230 V/60 Hz 11055737
IQ/OQ Documentation B-290 11057023
OQ Documentation B-290 11057024

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B-290 Operation Manual, Version M
3.2 Technical data overview
Table 3-6: Technical data Mini Spray Dryer B-290
Power consumption max. 2900 W
Connection voltage 200–230 V ± 10 %
Frequency 50/60 Hz
Environmental conditions
Temperature
Altitude
Humidity
for indoor use only
5–40 °C
up to 2000 m
maximum relative humidity 80 % for temperatures up to
31 °C decreasing linearly to 50 % relative humidity at 40 °C
Evaporating capacity 1.0 l/h H2O, higher for organic solvents
Airflow max. of 35 m3/h
Motor control Frequency converter
Max. temperature input 220 °C
Heating capacity 2300 W
Heating control PT-100, fuzzy logic, control accuracy ± 2 °C
Interface Serial port RS-232 for all parameters
Spray gas Compressed air or nitrogen/200–800 l/h, 5–8 bar
Nozzle tip diameter 0.7 mm standard, other sizes 1.4 and 2.0 mm available
Possible particle diameter range 1–25 µm
Mean residence time 1.0–1.5 sec.
Pollution degree 2
Installation category II
Dimensions (W×H×D) 65×110×70 cm
Weight 46 kg
Table 3-7: Technical data Spray Chilling accessory
Power consumption max. 400 W
Connection voltage 200–230 V ± 10 %
Frequency 50/60 Hz
Heating control (from B-290) PT-100, fuzzy logic, control accuracy ± 2 °C
Interface Serial port RS-232 for all parameters
Spray gas Compressed air or nitrogen/200–800 l/h, 5–8 bar
Nozzle tip diameter 0.7 mm standard, other sizes 1.4 and 2.0 mm available
Possible particle diameter range 20–200 µm
Mean residence time 1.0–1.5 sec.
Pollution degree 2
Installation category II
Dimensions (W×H×D) 20×20×30 cm
Weight 2.4 kg
Product vessel 87 mm height, 71 mm inner ∅
Batch volume 0.3 liter