Humalog KwikPen User manual

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PV 5594AMP
Instructions for Use
HUMALOG®KwikPen™
insulin lispro injection (rDNA origin)
Read the Instructions for Use before you start taking HUMALOG and each time you
get a refill. There may be new information. This information does not take the place
of talking to your healthcare provider about your medical condition or your
treatment.
HUMALOG®KwikPen™ (“Pen”) is a disposable pen containing 3 mL (300 units) of U-
100 HUMALOG®[insulin lispro injection (rDNA origin)] insulin. You can inject from 1
to 60 units in a single injection.
Do not share your HUMALOG KwikPen or needles with anyone else. You may
give an infection to them or get an infection from them.
This Pen is not recommended for use by the blind or visually impaired
without the assistance of a person trained in the proper use of the product.

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Supplies you will need to give your HUMALOG injection:
HUMALOG KwikPen
HUMALOG KwikPen compatible needle (Becton, Dickinson and Company Pen
Needles recommended)
Alcohol swab
Preparing HUMALOG KwikPen:
Wash your hands with soap and water.
Check the HUMALOG KwikPen Label to make sure you are taking the right type
of insulin. This is especially important if you use more than 1 type of insulin.
Do not use HUMALOG past the expiration date printed on the Label.
Always use a new needle for each injection to help ensure sterility and prevent
blocked needles.
Step 1:
Pull the Pen Cap straight off.
Wipe the Rubber Seal with an alcohol
swab.
Do not twist the cap.
Do not remove the KwikPen Label.
HUMALOG should look clear and
colorless. Do not use HUMALOG if it is
thick, cloudy, colored, has solid particles
or clumps in it.
Step 2:
Pull off the Paper Tab from Outer Needle
Shield.

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Step 3:
Push the capped Needle straight onto the
Pen and turn the Needle forward until it is
tight.
Step 4:
Pull off the Outer Needle Shield.Do not
throw it away.
Pull off the Inner Needle Shield and throw
it away.
Priming your HUMALOG KwikPen:
Prime before each injection.Priming ensures the Pen is ready to dose and
removes air that may collect in the cartridge during normal use. If you do not prime
before each injection, you may get too much or too little insulin.
Step 5:
Turn the Dose Knob to select 2 units.
Step 6:
Hold your Pen with the Needle pointing
up. Tap the Cartridge Holder gently to
collect air bubbles at the top.

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Step 7:
Hold your Pen with Needle pointing up.
Push the Dose Knob in until it stops,and
“0” is seen in the Dose Window.Hold the
Dose Knob in and count to 5 slowly.
A stream of insulin should be seen
from the needle.
-If you do not see a stream of
insulin, repeat steps 5 to 7, no
more than 4 times.
-If you still do not see a stream
of insulin, change the needle
and repeat steps 5 to 7.
Selecting your dose:
Step 8:
Turn the Dose Knob to select the number
of units you need to inject.The Dose
Indicator should line up with your dose.
The dose can be corrected by
turning the Dose Knob in either
direction until the correct dose
lines up with the Dose Indicator.
The even numbers are printed on
the dial. The odd numbers, after
the number 1, are shown as full
lines.
(10 units shown)
(15 units shown)

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The HUMALOG KwikPen will not let you dial more than the number of units left
in the Pen.
If your dose is more than the number of units left in the Pen, you may either:
-inject the amount left in your Pen and then use a new Pen to give the rest
of your dose, or
-get a new Pen and inject the full dose.
The Pen is designed to deliver a total of 300 units of insulin. The cartridge
contains an additional small amount of insulin that can’t be delivered.
Giving your HUMALOG injection:
Inject your HUMALOG as your healthcare provider has shown you.
Change (rotate) your injection site for each injection.
Do not try to change your dose while injecting HUMALOG.
Step 9:
Choose your injection site.
HUMALOG is injected under the skin
(subcutaneously) of your stomach area,
buttocks, upper legs or upper arms.
Wipe the skin with an alcohol swab, and
let the injection site dry before you inject
your dose.
Step 10:
Insert the Needle into your skin.

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Step 11:
Put your thumb on the Dose Knob and
push the Dose Knob in until it stops. Hold
the Dose Knob in and slowly count to
5.
Step 12:
Pull the Needle out of your skin.
You should see “0” in the Dose Window.
If you do not see “0” in the Dose
Window, you did not receive your full
dose.
If you see blood after you take the
Needle out of your skin, press the
injection site lightly with a piece of gauze
or an alcohol swab. Do not rub the area.
Adrop of insulin at the needle tip is
normal. It will not affect your dose.
If you do not think you received your
full dose, do not take another dose.
Call Lilly or your healthcare provider for
assistance.
Step 13:
Carefully replace the Outer Needle
Shield.

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Step 14:
Unscrew the capped Needle and throw it
away.
Do not store the Pen with the Needle
attached to prevent leaking, blocking of
the Needle, and air from entering the
Pen.
Step 15:
Replace the Pen Cap by lining up the Cap
Clip with the Dose Indicator and pushing
straight on.
After your injection:
Put your used needles and pens in a FDA-cleared sharps disposal container
right away after use. Do not throw away (dispose of) loose needles and pens
in your household trash.
If you do not have a FDA-cleared sharps disposal container, you may use a
household container that is:
-made of a heavy-duty plastic,
-can be closed with a tight-fitting, puncture-resistant lid, without sharps
being able to come out,
-upright and stable during use,
-leak-resistant, and
-properly labeled to warn of hazardous waste inside the container.
When your sharps disposal container is almost full, you will need to follow your
community guidelines for the right way to dispose of your sharps disposal
container. There may be state or local laws about how you should throw away
used needles and pens. For more information about safe sharps disposal, and
for specific information about sharps disposal in the state that you live in, go
to the FDA’s website at: http://www.fda.gov/safesharpsdisposal

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How should I store my HUMALOG KwikPen?
Store unused HUMALOG Pens in the refrigerator at 36°F to 46°F (2°C to 8°C).
The Pen you are currently using can be stored out of the refrigerator below
86°F (30°C).
Do not freeze HUMALOG. Do not use HUMALOG if it has been frozen.
Unused HUMALOG Pens may be used until the expiration date printed on the
Label, if kept in the refrigerator.
The HUMALOG Pen you are using should be thrown away after 28 days, even if
it still has insulin left in it.
Keep HUMALOG away from heat and out of the light.
General information about the safe and effective use of HUMALOG KwikPen
Keep HUMALOG KwikPen and needles out of the reach of children.
Do not use your Pen if any part looks broken or damaged.
Always carry an extra Pen in case yours is lost or damaged.
If you can not remove the Pen Cap, gently twist the Pen Cap back and forth,
and then pull the Pen Cap straight off.
If it is hard to push the Dose Knob or the Pen is not working the right way:
-Your Needle may be blocked.Put on a new Needle and prime the Pen.
-You may have dust, food, or liquid inside the Pen. Throw the Pen away and
get a new one.
-It may help to push the Dose Knob more slowly during your injection.
Use the space below to keep track of how long you should use each HUMALOG
KwikPen.
-Write down the date you start using your HUMALOG KwikPen. Count
forward 28 days.
-Write down the date you should throw it away.

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Example:
Pen 1 -First used on _______ + 28 days = Throw out on ______
Date Date
Pen 1 -First used on _______ Throw out on _______
Date Date
Pen 2 -First used on _______ Throw out on _______
Date Date
Pen 3 -First used on _______ Throw out on _______
Date Date
Pen 4 -First used on _______ Throw out on _______
Date Date
Pen 5 -First used on _______ Throw out on _______
Date Date
If you have any questions or problems with your HUMALOG KwikPen, contact Lilly at
1-800-Lilly-Rx (1-800-545-5979) or call your healthcare provider for help.For more
information on HUMALOG KwikPen and insulin, go to www.humalog.com.
These Instructions for Use have been approved by the U.S. Food and Drug
Administration.
Humalog®and Humalog®KwikPen™ are trademarks of Eli Lilly and Company.
Marketed by: Lilly USA, LLC
Indianapolis, IN 46285, USA
Copyright ©2007, 2013, Eli Lilly and Company. All rights reserved.
Humalog KwikPen meets the current dose accuracy and functional requirements of
ISO 11608-1:2000.
Revised: January 30, 2013
PV 5594AMP