National Instruments USB device 622x User manual

USER GUIDE
NI USB-622x/625x/628xOEM
M Series USB-6221/6225/6229/6251/6255/6259/6281/6289 OEM Devices
This document provides dimensions, pinouts, and information
about the connectors, switch, LEDs, and chassis ground of the National
Instruments USB-6221 OEM, USB-6225 OEM, USB-6229 OEM,
USB-6251 OEM, USB-6255 OEM, USB-6259 OEM, USB-6281 OEM,
and USB-6289 OEM devices. It also explains how to modify the USB
device name in Microsoft Windows.
Caution There are no product safety, electromagnetic compatibility (EMC), or
CE marking compliance claims made for the USB-622x/625x/628xOEM devices.
Conformity to any and all compliance requirements rests with the end product supplier.
Caution (USB-628xDevices) Exercise caution when placing USB-628xOEM devices inside
an enclosure. Auxiliary cooling may be necessary to keep the device under the maximum
ambient temperature rating of 45 °C, as specified in the NI 628x Specifications.
Figure 1 shows the USB-6221/6251/6281 OEM and
USB-6225/6229/6255/6259/6289 OEM devices.
Figure 1. USB-622x/625x/628xOEM Devices
USB-6221/6251/6281 USB-6225/6229/6255/6259/6289

NI USB-622x/625x/628x OEM User Guide 2 ni.com
Refer to the NI 622x Specifications document for USB-6221/6225/6229
specifications, the NI 625x Specifications document for
USB-6251/6255/6259 specifications, and the NI 628x Specifications
document for USB-6281/6289 specifications. Refer to the M Series User
Manual for more information about USB-622x/625x/628xdevices.
You can find all documentation at ni.com/manuals.
Dimensions
Figure 2 shows the dimensions of the USB-6221/6251/6281 OEM device.

©National Instruments Corporation 3 NI USB-622x/625x/628x OEM User Guide
Figure 2. USB-6221/6251/6281 OEM Dimensions in Inches (Millimeters)
0.436 (11.07)
0.392 (9.96)
0.362 (9.19)
0.162 (4.11)
0.062 (1.57)
0.000 (0.00)
0.396 (10.06)
0.304 (7.72)
0.256 (6.50)
0.116 (2.95)
0.000 (0.00)
6.950 (176.53)
4x 6.718 (170.63)
6.270 (159.26)
6.140 (155.96)
5.930 (150.62)
0.000 (0.00)
0.200 (5.08)
2.072 (52.63) 3.296 (83.72)
6.200 (157.48)
6.400 (162.56)
0.000 (0.00) 6.400 (162.56)
0.393 (9.98) 0.200 (5.08)
0.918 (23.32) 3.734 (94.84) 3.730 (94.74) 3.180 (80.77) 3.220 (81.79) 3.198 (81.22) 6.013 (152.74) 5.900 (149.86) 5.210 (132.33) 0.390 (9.91)
1.057 (26.85) 1.750 (44.45) 2.300 (58.42) 2.606 (66.19) 3.080 (78.23)
0.200 (5.08)
5.290 (134.37)
6.140 (155.96)
0.304 (7.72)
0.515 (13.08)
2X Ø 0.140 Cutout
in Panel for LEDs
Ø 0.330 Cutout in Panel
for Power Connector
7X Ø 0.125 (3.18)
4X Ø 0.110 (2.79)
0.609 (15.47)
0.442 (11.23)

NI USB-622x/625x/628x OEM User Guide 4 ni.com
Figure 3 shows the dimensions of the USB-6225/6229/6255/6259/6289
OEM device.
Figure 3. USB-6225/6229/6255/6259/6289 OEM Dimensions in Inches (Millimeters)
0.436 (11.07)
0.392 (9.96)
0.362 (9.19)
0.162 (4.11)
0.062 (1.57)
0.000 (0.00)
0.396 (10.06)
0.304 (7.72)
0.256 (6.50)
0.116 (2.95)
0.000 (0.00)
6.950 (176.53)
4x 6.718 (170.63)
6.270 (159.26)
6.140 (155.96)
5.930 (150.62)
5.839 (148.31)
5.499 (139.67)
0.000 (0.00)
0.200 (5.08)
2.072 (52.63) 3.296 (83.72)
6.200 (157.48)
6.400 (162.56)
0.000 (0.00) 6.400 (162.56)
0.393 (9.98) 0.200 (5.08)
0.918 (23.32) 3.734 (94.84) 3.730 (94.74) 3.180 (80.77) 3.220 (81.79) 3.198 (81.22) 6.013 (152.74) 5.900 (149.86) 5.210 (132.33) 0.390 (9.91)
1.057 (26.85) 1.750 (44.45) 2.300 (58.42) 2.606 (66.19) 3.080 (78.23)
0.200 (5.08)
5.290 (134.37)
6.140 (155.96)
0.304 (7.72)
2X Ø 0.140 Cutout
in Panel for LEDs
Ø 0.330 Cutout in Panel
for Power Connector
7X Ø 0.125 (3.18)
4X Ø 0.110 (2.79)
0.515 (13.08)
0.609 (15.47)
0.442 (11.23)

©National Instruments Corporation 5 NI USB-622x/625x/628x OEM User Guide
I/O Connector Pinouts
Figures 4 through 9 show the connector pinouts for the USB-6221 OEM,
USB-6225 OEM, USB-6229 OEM, USB-6251 OEM, USB-6255 OEM,
USB-6259 OEM, USB-6281 OEM, and USB-6289 OEM devices.
Refer to the M Series User Manual at ni.com/manuals for more
information about USB-622x/625x/628xsignals and how to connect them.

NI USB-622x/625x/628x OEM User Guide 6 ni.com
Figure 4. USB-6221 OEM Connector Pinout
AO 0
AO 1
AI GND
AI GND
AI GND
AI 8
AI 1
AI GND
AI 10
AI 3
AI GND
AI 12
AI 5
AI GND
AI 14
AI 7
AI GND
AO GND
AO GND
NC
AI 0
AI GND
AI 9
AI 2
AO GND
AI SENSE
AI GND
AI 11
AI 4
AI GND
AI 13
AI 6
AI GND
AI 15
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
P0.0
P0.1
P0.2
P0.3
P0.4
P0.5
P0.6
P0.7
PFI 0
PFI 1
PFI 2
PFI 3
PFI 4
PFI 5
PFI 6
PFI 7
PFI 8
PFI 9
PFI 10
PFI 11
PFI 12
PFI 13
PFI 14
PFI 15
+5 V
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
+5 V
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
36
38
40
42
44
46
48
50
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
35
37
39
41
43
45
47
49
Bank 0
Bank 0
Bank 0
50-Pin Digital Connector
34-Pin Analog Connector
NC = No Connect
Bank 0

©National Instruments Corporation 7 NI USB-622x/625x/628x OEM User Guide
Figure 5. USB-6225 OEM Connector Pinout
AO 0
AO 1
AI GND
AI GND
AI GND
AI 8
AI 1
AI GND
AI 10
AI 3
AI GND
AI 12
AI 5
AI GND
AI 14
AI 7
AI GND
AO GND
AO GND
NC
AI 0
AI GND
AI 9
AI 2
AO GND
AI SENSE
AI GND
AI 11
AI 4
AI GND
AI 13
AI 6
AI GND
AI 15
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
AI GND
AI 24
AI 17
AI GND
AI 26
AI 19
AI GND
AI 28
AI 21
AI 30
AI GND
AI 31
AI 32
AI 33
AI 42
AI GND
AI 43
AI SENSE 2
AI GND
AI 25
AI GND
AI 27
AI 20
AI GND
AI 16
AI 18
AI 29
AI 22
AI 23
AI 40
AI GND
AI 41
AI 34
AI 35
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
P0.0
P0.1
P0.2
P0.3
P0.4
P0.5
P0.6
P0.7
PFI 0
PFI 1
PFI 2
PFI 3
PFI 4
PFI 5
PFI 6
PFI 7
PFI 8
PFI 9
PFI 10
PFI 11
PFI 12
PFI 13
PFI 14
PFI 15
+5 V
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
+5 V
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
36
38
40
42
44
46
48
50
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
35
37
39
41
43
45
47
49
AI 36
AI GND
AI 37
AI 38
AI 47
AI GND
AI 56
AI 49
AI 50
AI 59
AI GND
AI 60
AI 53
AI 54
AI 63
AI GND
AI 72
AI 65
AI 66
AI 75
AI GND
AI 76
AI 69
AI 70
AI 79
AI 44
AI GND
AI 46
AI 48
AI 57
AI GND
AI 58
AI 45
AI 39
AI 51
AI 52
AI 61
AI GND
AI 62
AI 55
AI 64
AI 73
AI GND
AI 74
AI 67
AI 68
AI 77
AI GND
AI 78
AI 71
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
36
38
40
42
44
46
48
50
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
35
37
39
41
43
45
47
49
Bank 0
Bank 0
50-Pin Analog/Digital
Connectors
34-Pin Analog Connectors
Bank 1
Bank 1
Bank 1
Bank 0
Bank 1
Bank 0
NC = No Connect

NI USB-622x/625x/628x OEM User Guide 8 ni.com
Figure 6. USB-6229 OEM Connector Pinout
AO 0
AO 1
AI GND
AI GND
AI GND
AI 8
AI 1
AI GND
AI 10
AI 3
AI GND
AI 12
AI 5
AI GND
AI 14
AI 7
AI GND
AO GND
AO GND
NC
AI 0
AI GND
AI 9
AI 2
AO GND
AI SENSE
AI GND
AI 11
AI 4
AI GND
AI 13
AI 6
AI GND
AI 15
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
AO 2
AO 3
AI GND
AI GND
AI GND
AI 24
AI 17
AI GND
AI 26
AI 19
AI GND
AI 28
AI 21
AI GND
AI 30
AI 23
AI GND
AO GND
AO GND
NC
AI 16
AI GND
AI 25
AI 18
AO GND
AI SENSE 2
AI GND
AI 27
AI 20
AI GND
AI 29
AI 22
AI GND
AI 31
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
P0.0
P0.1
P0.2
P0.3
P0.4
P0.5
P0.6
P0.7
PFI 0
PFI 1
PFI 2
PFI 3
PFI 4
PFI 5
PFI 6
PFI 7
PFI 8
PFI 9
PFI 10
PFI 11
PFI 12
PFI 13
PFI 14
PFI 15
+5 V
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
+5 V
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
36
38
40
42
44
46
48
50
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
35
37
39
41
43
45
47
49
P0.8
P0.9
P0.10
P0.11
P0.12
P0.13
P0.14
P0.15
P0.16
P0.17
P0.18
P0.19
P0.20
P0.21
P0.22
P0.23
P0.24
P0.25
P0.26
P0.27
P0.28
P0.29
P0.30
P0.31
+5 V
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
+5 V
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
36
38
40
42
44
46
48
50
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
35
37
39
41
43
45
47
49
Bank 0
Bank 0
50-Pin Digital Connectors
34-Pin Analog Connectors
Bank 1
Bank 1
NC = No Connect NC = No Connect
Bank 1
Bank 0
Bank 1
Bank 0

©National Instruments Corporation 9 NI USB-622x/625x/628x OEM User Guide
Figure 7. USB-6251/6281 OEM Connector Pinout
AO 0
AO 1
AI GND
AI GND
AI GND
AI 8
AI 1
AI GND
AI 10
AI 3
AI GND
AI 12
AI 5
AI GND
AI 14
AI 7
AI GND
AO GND
AO GND
APFI 0
AI 0
AI GND
AI 9
AI 2
AO GND
AI SENSE
AI GND
AI 11
AI 4
AI GND
AI 13
AI 6
AI GND
AI 15
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
P0.0
P0.1
P0.2
P0.3
P0.4
P0.5
P0.6
P0.7
PFI 0
PFI 1
PFI 2
PFI 3
PFI 4
PFI 5
PFI 6
PFI 7
PFI 8
PFI 9
PFI 10
PFI 11
PFI 12
PFI 13
PFI 14
PFI 15
+5 V
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
+5 V
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
36
38
40
42
44
46
48
50
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
35
37
39
41
43
45
47
49
Bank 0
Bank 0
50-Pin Digital Connector
34-Pin Analog Connector
Bank 0
Bank 0

NI USB-622x/625x/628x OEM User Guide 10 ni.com
Figure 8. USB-6255 OEM Connector Pinout
AO 0
AO 1
AI GND
AI GND
AI GND
AI 8
AI 1
AI GND
AI 10
AI 3
AI GND
AI 12
AI 5
AI GND
AI 14
AI 7
AI GND
AO GND
AO GND
APFI 0
AI 0
AI GND
AI 9
AI 2
AO GND
AI SENSE
AI GND
AI 11
AI 4
AI GND
AI 13
AI 6
AI GND
AI 15
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
AI GND
AI 24
AI 17
AI GND
AI 26
AI 19
AI GND
AI 28
AI 21
AI 30
AI GND
AI 31
AI 32
AI 33
AI 42
AI GND
AI 43
AI SENSE 2
AI GND
AI 25
AI GND
AI 27
AI 20
AI GND
AI 16
AI 18
AI 29
AI 22
AI 23
AI 40
AI GND
AI 41
AI 34
AI 35
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
P0.0
P0.1
P0.2
P0.3
P0.4
P0.5
P0.6
P0.7
PFI 0
PFI 1
PFI 2
PFI 3
PFI 4
PFI 5
PFI 6
PFI 7
PFI 8
PFI 9
PFI 10
PFI 11
PFI 12
PFI 13
PFI 14
PFI 15
+5 V
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
+5 V
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
36
38
40
42
44
46
48
50
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
35
37
39
41
43
45
47
49
AI 36
AI GND
AI 37
AI 38
AI 47
AI GND
AI 56
AI 49
AI 50
AI 59
AI GND
AI 60
AI 53
AI 54
AI 63
AI GND
AI 72
AI 65
AI 66
AI 75
AI GND
AI 76
AI 69
AI 70
AI 79
AI 44
AI GND
AI 46
AI 48
AI 57
AI GND
AI 58
AI 45
AI 39
AI 51
AI 52
AI 61
AI GND
AI 62
AI 55
AI 64
AI 73
AI GND
AI 74
AI 67
AI 68
AI 77
AI GND
AI 78
AI 71
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
36
38
40
42
44
46
48
50
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
35
37
39
41
43
45
47
49
Bank 0
Bank 0
50-Pin Analog/Digital
Connectors
34-Pin Analog Connectors
Bank 1
Bank 1
Bank 1
Bank 0
Bank 1
Bank 0

©National Instruments Corporation 11 NI USB-622x/625x/628x OEM User Guide
Figure 9. USB-6259/6289 OEM Connector Pinout
AO 0
AO 1
AI GND
AI GND
AI GND
AI 8
AI 1
AI GND
AI 10
AI 3
AI GND
AI 12
AI 5
AI GND
AI 14
AI 7
AI GND
AO GND
AO GND
APFI 0
AI 0
AI GND
AI 9
AI 2
AO GND
AI SENSE
AI GND
AI 11
AI 4
AI GND
AI 13
AI 6
AI GND
AI 15
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
AO 2
AO 3
AI GND
AI GND
AI GND
AI 24
AI 17
AI GND
AI 26
AI 19
AI GND
AI 28
AI 21
AI GND
AI 30
AI 23
AI GND
AO GND
AO GND
APFI 1
AI 16
AI GND
AI 25
AI 18
AO GND
AI SENSE 2
AI GND
AI 27
AI 20
AI GND
AI 29
AI 22
AI GND
AI 31
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
P0.0
P0.1
P0.2
P0.3
P0.4
P0.5
P0.6
P0.7
PFI 0
PFI 1
PFI 2
PFI 3
PFI 4
PFI 5
PFI 6
PFI 7
PFI 8
PFI 9
PFI 10
PFI 11
PFI 12
PFI 13
PFI 14
PFI 15
+5 V
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
+5 V
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
36
38
40
42
44
46
48
50
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
35
37
39
41
43
45
47
49
P0.8
P0.9
P0.10
P0.11
P0.12
P0.13
P0.14
P0.15
P0.16
P0.17
P0.18
P0.19
P0.20
P0.21
P0.22
P0.23
P0.24
P0.25
P0.26
P0.27
P0.28
P0.29
P0.30
P0.31
+5 V
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
+5 V
2
4
6
8
10
12
14
16
18
20
22
24
26
28
30
32
34
36
38
40
42
44
46
48
50
1
3
5
7
9
11
13
15
17
19
21
23
25
27
29
31
33
35
37
39
41
43
45
47
49
Bank 0
Bank 0
50-Pin Digital Connectors
34-Pin Analog Connectors
Bank 1
Bank 1
Bank 1
Bank 0
Bank 1
Bank 0

NI USB-622x/625x/628x OEM User Guide 12 ni.com
Default Counter/Timer Pinouts
By default, NI-DAQmx routes the counter/timer inputs and outputs to the
PFI pins, shown in Table 1.
Table 1. NI-DAQmx Default Counter/Timer Pins
Counter/Timer Signal Default Terminal Name
CTR 0 SRC PFI 8
CTR 0 GATE PFI 9
CTR 0 AUX PFI 10
CTR 0 OUT PFI 12
CTR 0 A PFI 8
CTR 0 Z PFI 9
CTR 0 B PFI 10
CTR 1 SRC PFI 3
CTR 1 GATE PFI 4
CTR 1 AUX PFI 11
CTR 1 OUT PFI 13
CTR 1 A PFI 3
CTR 1 Z PFI 4
CTR 1 B PFI 11
FREQ OUT PFI 14

©National Instruments Corporation 13 NI USB-622x/625x/628x OEM User Guide
Attaching External LEDs
USB-622x/625x/628xOEM devices have two LEDs that reflect the device
state. The green READY LED indicates when the device is powered on and
configured as a USB device. The yellow ACTIVE LED indicates USB bus
activity.
Three connectors on the device allow you to connect an external LED
circuit to the device, as shown in Figure 10. To connect an external READY
LED, use E1 as the positive connection (+3.3 V) and E2 as the negative
connection. To connect an external ACTIVE LED, use E1 as the positive
connection and E3 as the negative connection. E1 is current limited with
a 100 Ωresistor to the 3.3 V internal supply. This configuration limits
the current to approximately 16 mA into a single external LED or
approximately 8 mA each when both LEDs are lit. You also can limit this
current further by using external resistors, also shown in Figure 10.
Figure 10. Schematic for External LED Circuits
E1
External
READY
LED
External
ACTIVE
LED
E2
E3
100 Ω
3.3 V
OEM (On-Board)
E1E2E3

NI USB-622x/625x/628x OEM User Guide 14 ni.com
Power Switch
The power switch on the USB-622x/625x/628xOEM device powers the
device on and off. Figure 11 shows the pins on the power switch and
circuitry.
Figure 11. Schematic for the Power Switch
Pin 1, VDC In, is connected to VDC through the fuse (reference designator
XF1). The VDC is the voltage provided by the power supply through the
power connector (reference designator J4/J6/J81) and must be 11–30 VDC,
20 W.
Pin 2, VDC Out, provides power to the circuitry on the device. When the
switch is in the On position, the VDC power supply from pin 1 is routed to
pin 2.
Pin 3, 100 kΩto Ground, connects pin 2 to ground through a 100 kΩ
resistor when the switch is in the Off position.
1 The power connector is designated as J4 on USB-6225/6255 OEM devices, J6 on USB-6221/6229 OEM devices, and J8 on
USB-6251/6259/6281/6289 OEM devices.
J4/J6/J8
VDC Out VDC In
XF1
Switch
123
NC NC
100 kΩ
SW1
Outer
Shell
SW1 XF1
FUSE
3
Power to
Device
J4/J6/J8
Power
Connector
1
2
100 kΩ
100 kΩ
to Ground

©National Instruments Corporation 15 NI USB-622x/625x/628x OEM User Guide
Connecting the USB-622x/625x/628xOEM Device to
Your Chassis
The USB-622x/625x/628xOEM device includes several plated mounting
holes that are designed for customer grounded connections, as shown in
Figure 12.
Caution Do not use the holes labeled A in Figure 12 as mounting holes.
Figure 12. Customer Mounting Holes
(USB-6225/6229/6255/6259/6289 OEM Shown)
Caution (USB-628xDevices) Exercise caution when placing USB-628xOEM devices inside
an enclosure. Auxiliary cooling may be necessary to keep the device under the maximum
ambient temperature rating of 45 °C, as specified in the NI 628x Specifications.
Mounting Hole Connected
to Chassis Ground
A
A
A
Do Not Use These
as Mounting Holes
A

NI USB-622x/625x/628x OEM User Guide 16 ni.com
Replacing Fuses
USB-622x/625x/628xOEM devices have a replaceable T 2A 250V
(5 ×20 mm) fuse that protects the device from overcurrent through the
power connector.
(USB-628xDevices Only) USB-628xOEM devices also have a replaceable
F 2A 125V fuse that protects the device from overcurrent through the +5 V
terminal(s).
Replacement fuse information can be found in Table 2. To replace a broken
fuse in USB-622x/625x/628xOEM devices, complete the following steps.
1. Power down and unplug the device.
2. Replace the broken fuse while referring to Figure 13 for the fuse
locations.
Figure 13. USB-622x/625x/628xOEM Fuse Locations
1T 2A 250V (5 x 20 mm) Fuse
2F2A 125V Fuse on USB-628xOEM Devices
2
1

©National Instruments Corporation 17 NI USB-622x/625x/628x OEM User Guide
Device Components
Table 2 contains information about the components used for interfacing
and interacting with the USB-622x/625x/628xOEM device.
Table 2. USB-622x/625x/628xOEM Components
Component Reference Designator(s) on PCB Manufacturer
Manufacturer
Part Number
LEDs DS1 Dialight 553-0332
34-pin connectors (USB-6221/6251/6281 OEM) J1 3M N2534-6002RB
(USB-6225/6229/6255/6259/6289
OEM) J1, J2
50-pin connectors (USB-6221/6251/6281 OEM) P1 3M N2550-6002UB
(USB-6225/6229/6255/6259/6289
OEM) P1, P2
USB connector J3 AMP 787780-1
Power connector (USB-6221/6229 OEM) J6 Switchcraft 722RA
(USB-6225/6255 OEM) J4
(USB-6251/6259/6281/6289 OEM) J8
Power switch SW1 ITT Industries,
Cannon
E101J1A3QE2
T 2A 250V fuse XF1 Littelfuse 218.002XP
F 2A 125V fuse (USB-6281/6289 OEM) F1 Littelfuse 0453002
68-pin
connectors*
(USB-6221 OEM) J8 Honda PCS-E68RLMD1+
(USB-6225/6229/6255 OEM) J7, J8
(USB-6251/6281 OEM) J7
(USB-6259/6289 OEM) J6, J7
*Optional mass termination connectors. These are not populated by default.

NI USB-622x/625x/628x OEM User Guide 18 ni.com
Modifying the USB Device Name in Microsoft Windows
You can change how the USB-622x/625x/628xOEM device name appears
when users install the device in both the Found New Hardware Wizard that
appears when the device is initially installed and in the Windows Device
Manager.
Windows Vista/XP Users
Figure 14 depicts how a USB-6251 OEM device name appears in the
Found New Hardware Wizard and Windows Device Manager.
Figure 14. USB-6251 OEM Device in the Found New Hardware Wizard and
Device Manager (Windows Vista/XP)
To modify the device name in the Found New Hardware Wizard and
Windows Device Manager in Microsoft Windows Vista/XP, complete the
following steps.
Note You must have NI-DAQmx 8.7 or later installed on your PC.
1. Locate the OEM
x .inf file in the y :\WINDOWS\inf\ directory,
where
x is the random number assigned to the INF file by Windows,
and
y :\ is the root directory where Windows is installed.

©National Instruments Corporation 19 NI USB-622x/625x/628x OEM User Guide
Note New security updates to Microsoft Vista and NI-DAQ 8.6 or later create random INF
files for NI hardware. Windows assigns random file numbers to all INF files, which causes
the user to search through several INF files until the correct file is located.
If you want to revert back, save a copy of this file as
OEM x _original.inf in a different location.
2. Edit the device INF file by opening OEM
x .inf with a text editor.
At the bottom of this file are the descriptors where Windows looks to
identify the device. Locate the two lines of text that contain in quotes
the descriptors for the device name you are modifying. Change the
descriptor on both lines to the new device name, as shown in Figure 15.
Figure 15. INF File Descriptors Changed to “My Device” (Windows Vista/XP)
3. Save and close the INF file.
4. Go to the Windows Device Manager.
(Windows Vista) In the Device Manager, notice that the OEM device
now appears as My Device, as shown in Figure 16.
(Windows XP) In the Device Manager, right-click the OEM device under
Data Acquisition Devices, and select Uninstall. Power down the OEM
device and disconnect the USB cable from your PC.
Original File
Modified File

NI USB-622x/625x/628x OEM User Guide 20 ni.com
When you reconnect and power on the device, it appears as My Device in
the Found New Hardware Wizard and Windows Device Manager, as shown
in Figure 16.
Note When the device is initially installed, the Windows alert message may display the
following: Found New Hardware: M Series USB 62
xx (OEM). This message appears
for a few seconds until the custom name appears and the Found New Hardware Wizard is
launched. This alert message device name cannot be changed.
Figure 16. “My Device” in the Found New Hardware Wizard and
Device Manager (Windows Vista/XP)
Note Modifying the INF file will not change the USB-622x/625x/628xOEM device name
in Measurement & Automation Explorer (MAX).