REPLIGEN CTech FlowVPX System User manual

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© 2023 Repligen Corporation. All rights reserved. The trademarks mentioned herein
are the property of Repligen Corporation and/or its affiliate(s) or their respective owners.
DOC0211 eRev. 1.0 8/15/2023
CTech™ FlowVPX®
System
User Guide

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The information contained in this document is subject to change without notice.
With respect to documentation accompanying Product Repligen makes no warranty, express or implied. Any and all warranties
related to the documentation accompanying Product are expressly disclaimed. Customer shall refer to the terms and conditions of
sale governing the transaction for any and all warranties for the Product.
Repligen Corporation shall not be liable for errors contained herein or for incidental or consequential damages in connection with
the furnishing, performance, or use of this material.
No part of this document may be photocopied, reproduced, or translated to another language without the prior written consent of
Repligen Corporation.
Products are not intended for diagnostic or therapeutic use or for use in vivo with humans or animals.
For further information, please contact Repligen Corporation at www.repligen.com.
©2023 Repligen Corporation. All rights reserved. The trademarks mentioned herein are the property of Repligen Corporation and/or
its affiliate(s) or their respective owners.
Customer Support
[e-mail]
[phone]
Repligen Corporation
Process Analytics Offices and Manufacturing Facility
685 Route 202/206
Bridgewater, NJ 08807, USA
www.repligen.com

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Contents
5.2.1 FlowVPX Status Indicator Light ...................................................................................................................................... 12
5.2.2 Power and Integration Connector.................................................................................................................................. 12
5.2.3 USB Communications Connector ................................................................................................................................... 12
5.2.4 Flow Smart Input............................................................................................................................................................ 13
5.2.5 Storage ........................................................................................................................................................................... 13
5.7.1 Transmission Tool .......................................................................................................................................................... 16
5.8.1 The FlowVPX Power Cable (EC0205) .............................................................................................................................. 17
5.8.2 The FlowVPX Power and I/O Splitter Cable (EC0208) .................................................................................................... 17
5.8.3 The FlowVPX I/O External Cable (EC0214) ..................................................................................................................... 17
5.8.4 The FlowVPX Extender Power Cable (EC0206)............................................................................................................... 17
5.8.5 The FlowVPX USB Cable (EC0207) .................................................................................................................................. 17
5.10.1 The FlowVPX Delivery Fiber ........................................................................................................................................... 18
5.11.1 Beams Source................................................................................................................................................................. 19
5.11.2 Beams Controller............................................................................................................................................................ 20
5.11.3 FlowVPX Detector Cable (EC0328) ................................................................................................................................. 20
5.11.4 Beams Source 3 m Extender Cable (EC0337) ................................................................................................................. 20
5.11.5 Beams Detector 3 m Extender Cable (EC0338) .............................................................................................................. 20
10.1.1 Loading the Flow Cell Using the Cary 60 Light Source ................................................................................................... 31
10.1.2 Loading the Flow Cell Using the Beams Light Source..................................................................................................... 34
10.2.1 Unloading the Flow Cell Using the Cary 60 Light Source................................................................................................ 36
10.2.2 Unloading the Flow Cell Using the Beams Light Source................................................................................................. 37
13.1.1 Running a Different Sample (Using a Cary 60 Light Source)........................................................................................... 46
13.1.2 Unloading the XSA Unit (Using a Cary 60 Light Source) ................................................................................................. 46

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13.2.1 Running a Different Sample (Using a Beams Light Source)............................................................................................ 48
13.2.2 Unloading the XSA Unit (Using a Beams Light Source)................................................................................................... 48
List of tables
Table 1. Explanation of user attention phrases ......................................................................................................................................... 6
Table 2. Safety precautions for the FlowVPX System ................................................................................................................................6
Table 3. Regulatory information ................................................................................................................................................................7
Table 4. Mains supply information ............................................................................................................................................................8
Table 5. FlowVPX I/O cable (EC0214) pinout ...........................................................................................................................................26
Table 6. Troubleshooting issues and responses ......................................................................................................................................49
List of figures
Figure 1. CTech FlowVPX Instrument (Fully Assembled) Components....................................................................................................11
Figure 2. FlowVPX Head Components......................................................................................................................................................12
Figure 3. FlowVPX Detector Components................................................................................................................................................ 13
Figure 4. FlowVPX Flow Cell Components ...............................................................................................................................................14
Figure 5. FlowVPX Standard Mount Components ...................................................................................................................................15
Figure 6. FlowVPX System Suitability Adapter (XSA) components ..........................................................................................................15
Figure 7. Detector Validation Adapter (DVA) Components .....................................................................................................................16
Figure 8. Transmission Tool and Sample Vessel Components ................................................................................................................. 16
Figure 9. FlowVPX-Specific Cabling ..........................................................................................................................................................17
Figure 10. Connecting Items and Tools....................................................................................................................................................18
Figure 11. Cary 60 Spectrophotometer and Accessories .........................................................................................................................19
Figure 12. Beams Source, Controller, and Accessories ............................................................................................................................ 19
Figure 13. Computer and Accessories...................................................................................................................................................... 20
Figure 14. FlowVPX Head (Logo Side Down) ............................................................................................................................................ 21
Figure 15. Standard Mount Clamp on FlowVPX Head .............................................................................................................................21
Figure 16. 5 mm Ball End Driver............................................................................................................................................................... 21
Figure 17. Clamp Handle Installation .......................................................................................................................................................22
Figure 18. Rotate Clamp Handle ..............................................................................................................................................................22
Figure 19. Tighten Mounting Post Clamp Handle ....................................................................................................................................22
Figure 20. Install FlowVPX Head on Mounting Post.................................................................................................................................23
Figure 21. Lower FlowVPX Head on Mounting Post ................................................................................................................................23
Figure 22. Tighten Standard Mount Clamp Handle (Left) and Repositioning the Clamp Handle (Right).................................................23
Figure 23. Accessory Port in Back of Cary 60 Spectrophotometer ..........................................................................................................24
Figure 24. Detector Cable in Sample Compartment ................................................................................................................................24
Figure 25. Cary 60 Power Cable and USB Cable, Back Panel....................................................................................................................25
Figure 26. Fiber Optic Coupler Threaded Splice Bushing......................................................................................................................... 25
Figure 27. Connect Power and I/O Splitter Cable (EC0208) to FlowVPX Head ........................................................................................25
Figure 28. FlowVPX I/O Cable Connections.............................................................................................................................................. 26
Figure 29. I/O External Cable (EC0214) to FlowVPX Head .......................................................................................................................26
Figure 30. USB Cable (EC0207) to FlowVPX Head ....................................................................................................................................27
Figure 31. FlowVPX USB cable (EC0207) to Computer.............................................................................................................................27
Figure 32. System Setup: Beams Controller Connections........................................................................................................................28
Figure 33. System Setup: FlowVPX Connections...................................................................................................................................... 28
Figure 34. Beams Power Brick and Cable................................................................................................................................................. 29
Figure 35. USB Computer Connections....................................................................................................................................................29

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Figure 36. ViPER Login Page.....................................................................................................................................................................30
Figure 37. My Applications: Quick Kinetics App....................................................................................................................................... 30
Figure 38. Method Input Menu: Select Flow Cell ....................................................................................................................................31
Figure 39. Load Button in Instrument Control Menu...............................................................................................................................31
Figure 40. Flow Cell Loading Instructions ................................................................................................................................................ 32
Figure 41. Flow Cell Loading Window: Enter Serial Number ...................................................................................................................33
Figure 42. Correct FX Connector Nut Orientation....................................................................................................................................33
Figure 43. Flow Cell Loading Instructions (Beams) .................................................................................................................................. 34
Figure 44. Correct Beams FX connector Nut Orientation ........................................................................................................................35
Figure 45. Unload Button in the Instrument Control Menu ....................................................................................................................36
Figure 46. Unload Flow Cell Confirmation Prompt .................................................................................................................................. 36
Figure 47. Flow Cell Unloading Using the Cary 60 Light Source...............................................................................................................37
Figure 48. Flow Cell Unloading Using the Beams Light Source ................................................................................................................38
Figure 49. Transmission Check Button in Instrument Control Menu.......................................................................................................39
Figure 50. Transmission Check Instructions (Cary 60) .............................................................................................................................40
Figure 51. Quick Check Button in Instrument Control Menu...................................................................................................................41
Figure 52. Quick Check Loading Window.................................................................................................................................................41
Figure 53. Quick Check Results ................................................................................................................................................................ 42
Figure 54. My Applications: Validate VPT App......................................................................................................................................... 43
Figure 55. System Suitability Button in Instrument Control Menu.......................................................................................................... 43
Figure 56. Start System Suitability Test Window ..................................................................................................................................... 44
Figure 57. System Suitability Test Instructions (Cary 60).........................................................................................................................44
Figure 58. Reference Standard Information Fields ..................................................................................................................................45
Abbreviations
C1D2 Class 1, Division 2
CE Conformité Européenne, or European Conformity
CEC Canadian Electrical Code
DVA Detector Validation Adapter
EMC Electromagnetic Compatibility
GMP Good Manufacturing Practice
IEC International Electrotechnical Commission
IP65 Ingress Protection: solids level 6, liquids level 5
LVD Low Voltage Directive
NaOH Sodium Hydroxide
NEC National Electrical Code
VPT Variable Pathlength Technology
XSA FlowVPX System Suitability Adapter

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1. Introduction
The CTech™ FlowVPX® System was designed and built to be the next-generation, in-line measurement instrument for monitoring
product concentration. The FlowVPX System allows concentration readings in excess of 250 mg/ml, adapts to various Flow Cell sizes
for process volume adaptation, and has built-in data acquisition and process control capabilities. Designed for use with the CTech™
ViPER® ANLYTX Software platform integrating data integrity and audit logging, the FlowVPX instrument is an extremely capable and
formidable tool for in-line process analytics.
This user guide provides general guidance for the use of the CTech FlowVPX System. For further optimization or troubleshooting
support, please contact your Repligen Variable Pathlength Technology (VPT) Support Specialist (email: analytics-
[e-mail]; phone: [phone]).
For a full listing of performance specifications of the FlowVPX System, please see the product specifications document CTech
FlowVPX System Specification Sheet DOC0206.
2. About this document
This manual uses several different phrases. Each phrase should draw the following level of attention:
Table 1. Explanation of user attention phrases
Phrase Description
Note: Points out useful information.
IMPORTANT Indicates information necessary for proper instrument operation.
3. Safety Notices
Table 2. Safety precautions for the FlowVPX System
Note: Do not discard any packaging materials. In the event the system needs to be shipped or moved safely after initial installation,
these are the most appropriate materials to keep the system secure for transportation.
Symbol Description
CAUTION
Caution, indicates a hazard that may result in a potentially hazardous situation that may result in personal injury
or death if proper operating procedures are not followed. Documentation must be consulted in all cases where
this symbol is marked. Do not proceed beyond a CAUTION notice until procedures and conditions of operation
are met as specified.
WARNING
Warning, indicates a hazard that may result in a moderately hazardous situation that may result in personal
injury or death if proper operating procedures are not followed. Documentation must be consulted in all cases
where this symbol is marked. Do not proceed beyond a WARNING notice until procedures and conditions of
operation are met as specified.
WARNING Warning, possibility of electric shock.

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4. Regulatory
Table 3. Regulatory information
CE Compliance
CE Compliance for the FlowVPX instrument is indicated by the following:
•The CE marking on the rear of the FlowVPX Head
•Repligen’s Analytics business document: CTech FlowVPX CE Declaration of Conformity CTIDC-0002
CE Compliance for the Beams System is indicated by the following:
•The CE marking on the bottom of the Beams Controller
•Repligen’s Analytics business document: Declaration of Conformity, CTech Beams System CTIDC-0005
CE compliance covers the FlowVPX Head, Detector, Fibrette® Optical Component, Repligen’s Analytics business-provided power
supply, three-meter cabling, and smart technology installed in every Flow Cell or System Suitability Adapter that mates with the
FlowVPX Head, Beams Source, and Beams Controller. FlowVPX installations utilizing cabling longer than three meters and/or
customer-provided 24 VDC power through the I/O cable have not been tested for CE compliance.
The CTech FlowVPX and Beams™ System have been designed and tested for compliance by independent testing laboratories in
accordance with the standards listed on the Declaration of Conformity documents listed above.
Under IEC 61010-1, the system is rated for measurement category I. Do not use this equipment for measurements within categories
II, III, and IV.
The FlowVPX System falls into pollution degree 2 as defined in IEC 61010-1.
Mains Supply
A power supply and location-specific power cord has been provided with the system. CE compliance and expected instrument
performance have only been tested with the following components.
Symbol Description
CE Compliance
The CE marking (conformité européenne, or “European conformity”) certifies that a product has met EU health,
safety, and environmental requirements, which ensure consumer safety.
UKCA
Compliance
The United Kingdom Conformity Assessment (UKCA) marking is used for products being placed on the market in
Great Britain and applies to most products for which the CE marking could be used.
KC Certification
Korea Certification (KC) is a product certification which ensures the conformity of products to Korean safety
standards. The KC mark is similar to the CE mark in the EU but involves different requirements and testing.
Hazardous
Locations
Compliance
(C1D2)
—
Hazardous Locations are areas where flammable liquids, vapors, gases, or combustible dusts are likely to occur
in quantities sufficient to cause a fire or explosion. A Class 1 (C1) location involves the presence of flammable
vapors or gases. A Division 2 (D2) location indicates that hazardous material is present only under abnormal
conditions.
IP65 Certification
The International Electrotechnical Commission (IEC) has developed ingress protection (IP) ratings, which grade
the resistance of an enclosure against the intrusion of dust or liquids. An IP65 Rating indicates that the product
has the highest level of dust protection and is able to withstand low-pressure water jets from all directions.
WEEE
Compliance
The EU has developed rules on waste from electrical and electronic equipment (WEEE) to steer manufacturing
towards sustainable production and consumption. The rules address environmental and other issues caused by
discarded electronics.

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Table 4. Mains supply information
Korean Class A statement
A급기기 (업무용 방송통신기자재)
이기기는 업무용(A급)으로 전자파적합기기로서
판매자 또는 사용자는 이점을 주의하시기 바라며,
가정 외의 지역에서 사용하는 것을 목적으로 합니다.
Translation: Class A (Broadcasting and Communication equipment for Business)
Sellers and users should note that this equipment is an electromagnetic device for business (class A), and is intended for use outside
the home.
Hazardous Location
The FlowVPX instrument, Beams controller, and Beams source have been tested and certified compliant with requirements for
Class 1, Division 2, Groups A, B, C, and D; 0°C ≤ Tamb ≤ 48°C.
The final installation and wiring method of the device must meet the requirements of National Electrical Code (NEC) for USA and
Canadian Electrical Code (CEC) for Canada and is subject to approval by the local authority having jurisdiction, expressed through a
note in the certificate and report. The relevant equipment is usually installed by the end user on a skid for their process and must
include cable trays to lay the cabling into.
Conditions of Use:
•To be supplied by a battery or Class 2 certified power supply.
•The interconnection cables between different components uses a power-limited tray cable (Type PLTC), as allowed for
applications supplied by a Class 2 or Class 3 power source. Alternatively, all components shall be installed in a NEMA 4
enclosure.
•USB connection to be used only in non-hazardous areas.
Component Power Voltage and Ratings
FlowVPX Instrument Mains Supply Voltage 24 VDC
Beams System Mains Supply Voltage 24 VDC
FlowVPX AC Power Supply Input Ratings 100 VAC—240 VAC and 47 Hz—63 Hz
Beams System AC Power Supply Input Ratings 100 VAC—240 VAC and 47 Hz—63 Hz
Beams Instrument Max Rated Current Draw 1.0 A
FlowVPX Instrument Max Rated Current Draw (24 VDC
Including FlowVPX)
600 mA
Max Instrument Input Power 20 W
FlowVPX Instrument Mains Supply Voltage 24 VDC
WARNING:Shock Hazard: Danger of electrocution. Good electrical grounding is essential to avoid potentially serious
shock hazards. A three-wire outlet with ground connection must be provided for the power supplies included with
the Beams System, Cary 60 light source, and computer. Make certain that power outlets are earth grounded at the
grounding pin.
CAUTION:It is the user’s responsibility to ensure any alternate power supply conforms with the required voltage and
current ratings.

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•The power supply must be properly certified for the location and installed according to the CEC and NEC wiring methods
accepted to the Local Authority Having Jurisdiction (LAHJ).
Installation Instructions (in C1D2 Hazardous Locations)
The connectors used shall be capable of being connected to one of the wiring methods as permitted by the NEC for the US or CE
Code, Part I, for Canada for the hazardous location in accordance with any applicable restrictions including issues such as the
routing, support, and maximum length.
Note:See the following United States and Canadian Code references for additional details on some permitted wiring methods for
Class I locations:
a) Sections 501.105(B)(6) or 501.140 of the NEC or Rule J18-160 of the CE Code, Part I for Extra - hard usage cord;
b) Section 501.105(B) of the NEC for Power-limited tray cable (Types PLTC or PLTC-ER), Instrumentation tray cable (Types ITC
or ITC-ER) and Tray cable (Types TC or TC-ER)) ; and
c) Rule J18-152 of the CE Code, Part I for Tray cable (Type TC), Armoured cable with overall nonmetallic jacket (TECK90),
Control and Instrumentation cable (Type ACIC) and Non-armoured control and instrumentation cable (Type CIC).
In the United States, cable assemblies and the associated separate plugs and sockets referenced in 8.8.1, shall be in accordance with
UL 2238 or UL 2237. In Canada, external connectors shall be in accordance with CSA C22.2 No. 159. Alternatively, cable assemblies
and the associated separate plugs and sockets may be used that comply with other relevant standards provided these other
standards include requirements that address the following:
a) The voltage and current rating of the cable assemblies and the associated separate plugs and sockets.
b) For field wiring applications, the suitability of the cable assemblies and the associated separate plugs and sockets for field
installation.
c) Use of the cable assemblies and the associated separate plugs and sockets with one or more of the permitted wiring
methods.
Note: Connectors evaluated to UL 1977 are not suitable for field wiring applications.
IP65 Certification
The FlowVPX instrument has been tested and certified for IP65 compliance according to IEC 60659. Testing was conducted with the
FlowVPX System fully assembled with Detector and Flow Cell with fresh seals installed. C Technologies document CTech FlowVPX
IP65 Declaration of Conformity CTIDC-0001 is included in shipment.
The Beams System has been tested and certified for IP65 compliance according to IEC 60659. Testing was conducted with the Beams
System in any configuration, fully assembled or on its own. The Declaration of Conformity, CTech Beams System CTIDC-0005 is
included in shipment.
WEEE Compliance
Repligen Corporation has met its obligations to the EU WEEE and Battery Directive by registering in those countries to which
Repligen Corporation is an importer. Repligen Corporation has also elected to join WEEE and Battery Compliance Schemes in some
countries to help manage customer returns at end-of-life.
CAUTION:Testing and certification does not include the FlowVPX power supply, which must be installed outside of the
hazardous location, or otherwise isolated from the hazardous environment.
WARNING:Explosion hazard for hazardous locations. Do not connect or disconnect any cabling while energized.

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The presence of the crossed-out wheeled bin label on this product implies that the product contains electrical or electronic materials
that may be hazardous and present a risk to human health and the environment when waste electrical and electronic equipment
(WEEE) is not handled correctly. Electrical and electronic equipment must be disposed of in an appropriate manner, separate from
standard unsorted waste streams. Users need to follow local recycling regulations to reduce adverse environmental impact in
connection with disposal of WEEE and to increase opportunities for reuse, recycling, and recovery of WEEE. As legislation and
disposal facilities may vary throughout the European Union member states, please contact Repligen Corporation
([e-mail]) for further information regarding the proper disposal of products marked with the crossed-out
wheeled bin label.
For disposal in countries outside of the European Union: This symbol is only valid for use within the European Union (EU). If you wish
to discard this product, please contact your local authorities for the correct method of disposal.
Environmental Conditions
For optimal performance, the ambient temperature should be between 20°C and 25°C and held constant (±2 degrees) throughout
operation. The area should be free of dust and have low humidity, with air conditioning recommended.
Acceptable conditions for safe operation: 0°C–48°C, 15%–80% RH (non-condensing), altitude up to 2000 meters.
5. FlowVPX Hardware and Accessories
The following is an introduction to the FlowVPX hardware and accessories, for familiarization of naming and purpose. Please review
all components and warnings before moving on to installation.
When fully assembled with Head, Detector, Flow Cell, and connecting nuts:
Weight: 4.08 kg (9 lbs)
Dimensions:120 x 100 x 230 mm (4.72 x 3.94 x 9.06 in)
CAUTION:Exposing the FlowVPX Head and Detector to elevated temperatures of 80°C or more may cause damage to
critical components.
CAUTION:Condensation buildup on the system’s components may impact readings. Be aware of sample temperatures
flowing through the FlowVPX System with respect to environment humidity to ensure no condensation appears on
critical optical surfaces.

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5.1 CTech FlowVPX Instrument
Figure 1. CTech FlowVPX Instrument (Fully Assembled) Components

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5.2 FlowVPX Head
Figure 2. FlowVPX Head Components
5.2.1 FlowVPX Status Indicator Light
The status indicator light changes color based on certain criteria.
Green, steady:Instrument powered
Green and blue, blinking:Instrument moving/reading
5.2.2 Power and Integration Connector
Connects FlowVPX instrument to power supply and allows communication to and from the FlowVPX instrument with process
automation systems.
Signal output on this connector is sent in the range of 0–5 VDC and/or 4–20 mA. This range can be configured in ViPER during I/O
configuration.
5.2.3 USB Communications Connector
Connects FlowVPX instrument to the computer for control with ViPER ANLYTX Software.
CAUTION:Avoid contact between the rubber wiper seals and sharp objects, as this may impact sealing operation around
reciprocating shaft.
CAUTION:Avoid exposure of the indicator LED housing to harsh chemicals, as it may discolor or add cloudiness to the
housing. Acceptable cleaning agents include 0.5M NaOH, de-ionized (DI) water, and 70% isopropyl alcohol.
Contact Repligen for further inquiries.

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5.2.4 Flow Smart Input
The FlowVPX instrument is equipped with electrical contacts to read a flash memory device on each Flow Cell to track serial
numbers, cycle life, and other critical parameters.
5.2.5 Storage
Place connector caps onto connectors when not in use.
5.3 FlowVPX Detector
The FlowVPX Detector reads light transmitted from the Flow Fibrette and is designed as a removable module that adapts to a Flow
Cell of any size.
For storage, place connector cap on connector when not in use. Place the detector in shipping box.
Figure 3. FlowVPX Detector Components
CAUTION:Do not scratch or damage the Window as this may affect the accuracy of optical readings. Do not drop the
Detector, as shocks may damage internal electronics.

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5.4 FlowVPX Flow Cell
The FlowVPX instrument is compatible with Flow Cells that have flow path diameters from 3 mm to 22 mm. Each Flow Cell is fitted
with a memory device which contains the serial number and uses information for smart integration with the ViPER platform.
Each Flow Cell also utilizes an industry-standard tube or pipe fitting.
For individual Flow Cell specifications, refer to the corresponding Specification Sheet included with the Flow Cell, available at
repligen.com, or upon request at [e-mail]
Figure 4. FlowVPX Flow Cell Components
5.5 FlowVPX Standard Mount
Designed to hold the FlowVPX Head between 0° (upright) and 110° for easy loading and unloading of Flow Cells.

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Figure 5. FlowVPX Standard Mount Components
5.6 FlowVPX System Suitability Adapter (XSA)
The FlowVPX System Suitability Adapter (XSA) couples with the Detector Validation Adapter (DVA) to allow certified standards to be
measured on the FlowVPX System, ensuring overall system function prior to use.
Figure 6. FlowVPX System Suitability Adapter (XSA) components

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5.7 FlowVPX Detector Validation Adapter (DVA)
The FlowVPX Detector Validation Adapter (DVA) enables raw transmission readings to the Detector, as well as CPV validation with
NIST traceable filters and cuvette adapters.
Figure 7. Detector Validation Adapter (DVA) Components
5.7.1 Transmission Tool
The Transmission Tool snaps directly onto the Detector Validation Adapter to couple either the Delivery Fiber or the Beams source
directly to the Detector.
Figure 8. Transmission Tool and Sample Vessel Components

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5.8 Cables
Figure 9. FlowVPX-Specific Cabling
5.8.1 The FlowVPX Power Cable (EC0205)
The FlowVPX power cable provides 24 VDC power to the FlowVPX Head.
5.8.2 The FlowVPX Power and I/O Splitter Cable (EC0208)
The FlowVPX System is capable of making an I/O connection to another system. This gives the user the ability to connect their
system to the FlowVPX instrument, letting the two systems communicate with each other.
The FlowVPX Power and I/O Splitter Cable couples power input from the power supply with I/O communications.
5.8.3 The FlowVPX I/O External Cable (EC0214)
The FlowVPX I/O External Cable allows for I/O communications and connection with alternate 24 VDC power supplies.
5.8.4 The FlowVPX Extender Power Cable (EC0206)
Provided with the FlowVPX System to allow for greater versatility in FlowVPX System placement. It is not recommended to use more
than one Extender Power Cable in series with the standard Power Cable.
5.8.5 The FlowVPX USB Cable (EC0207)
The FlowVPX System uses a USB cable to connect to the software installed on your computer device. The USB cable connects to the
FlowVPX Head and computer.
FlowVPX Power Supply—EC0205
(country-specific power cable,
US pictured)
FlowVPX I/O External
Cable—EC0214
FlowVPX USB
Cable—EC0207
FlowVPX Extender Power
Cable—EC0206
FlowVPX Power
and I/O Splitter
Cable—EC0208

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5.9 Connecting Items and Tools
Replacements for any of these items are available from Repligen.
Contact Repligen at US [phone] or [e-mail]
Figure 10. Connecting Items and Tools
5.10 Cary 60 Spectrophotometer and Accessories
Agilent Technologies’ Cary 60 spectrophotometer uses a Xenon flash lamp light source, which provides a wavelength range of
190 nm–1100 nm. Using the FlowVPX with the Cary 60 light source requires a Fiber Optic Coupler, provided by Repligen, to ensure
adequate light transmission through the Delivery Fiber to the FlowVPX instrument.
Note:Please reference documentation included with the Cary 60 spectrophotometer for component-specific requirements,
instructions, and safety considerations.
5.10.1 The FlowVPX Delivery Fiber
If using the Cary 60 spectrophotometer,the FlowVPX System requires a fiber optic cable to transmit the light from the Cary 60 to
the Flow Fibrette. This is called the FlowVPX Delivery Fiber. The Delivery Fiber included with the FlowVPX System is 3 m long; a
longer Delivery Fiber is available upon request.
CAUTION:Avoid bending the Delivery Fiber past a two-inch radius to ensure integrity of internal optical fiber.

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Figure 11. Cary 60 Spectrophotometer and Accessories
5.11 Beams System and Accessories
The CTech Beams System is a monochromatic LED light source and data acquisition module for integration with the FlowVPX System
for single wavelength applications.
Designed for manufacturing settings, the Beams System provides light source and detection capabilities in a small package, without
sacrificing any functionality of the FlowVPX instrument, such as motion control, I/O output, firmware, and smart cell reading.
Figure 12. Beams Source, Controller, and Accessories
5.11.1 Beams Source

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CTech™ FlowVPX® System
The Beams Source is housed in a stainless-steel canister that attaches directly to the top of the FlowVPX Head. The monochromatic
LED is available in four wavelengths: 260 nm, 272 nm, 280 nm, or 310 nm.
The status indicator light changes color based on certain criteria.
Green, steady:Instrument is powered on
Green, blinking:Instrument is emitting light
5.11.2 Beams Controller
The Beams Controller acts as the central hub for communication between the light source, the FlowVPX head, the detector, and the
software. The controller also supplies power to the Beams Source and the FlowVPX instrument.
The status indicator light changes color based on certain criteria.
Green, blinking: Instrument is powered on and connected to the software
Green and blue, blinking:Instrument is on and waiting to connect to software
White: Instrument is preparing for initialization
5.11.3 FlowVPX Detector Cable (EC0328)
The FlowVPX Detector Cable connects to the Beams controller and to the FlowVPX Detector.
5.11.4 Beams Source 3 m Extender Cable (EC0337)
The Beams Source 3 m Extender Cable is 3 meters in length and may be used to connect the Beams controller to the built-in cable on
the Beams Source. It is not recommended to use more than one Extender Cable in series with the Beams Source cable.
5.11.5 Beams Detector 3 m Extender Cable (EC0338)
The Beams Detector 3 m Extender Cable is 3 meters in length and may be used to connect the Beams controller to the FlowVPX
Detector in lieu of the FlowVPX Detector Cable (EC0328). It is not recommended to use more than one Extender Cable in series with
the Detector cable.
5.12 Computer and Accessories
The FlowVPX instrument is controlled by CTech™ ViPER® ANLYTX Software applications. The supplied laptop has been selected for
compatibility with the ViPER software. See the CTech FlowVPX System Specification Sheet DOC0206 for computer specifications.
Note: Please reference documentation included with the computer supplied with the FlowVPX System for component-specific
requirements, instructions, and safety considerations.
Figure 13. Computer and Accessories