Asus Prime H610M-R D4 User manual

Motherboard
PRIME H610M-R D4

ii
E19850
First Edition
February 2022
Copyright © 2022 ASUSTeK COMPUTER INC. All Rights Reserved.
No part of this manual, including the products and software described in it, may be reproduced,
transmitted, transcribed, stored in a retrieval system, or translated into any language in any form or by any
means, except documentation kept by the purchaser for backup purposes, without the express written
permission of ASUSTeK COMPUTER INC. (“ASUS”).
Product warranty or service will not be extended if: (1) the product is repaired, modied or altered, unless
such repair, modication of alteration is authorized in writing by ASUS; or (2) the serial number of the
product is defaced or missing.
ASUS PROVIDES THIS MANUAL “AS IS” WITHOUT WARRANTY OF ANY KIND, EITHER EXPRESS
OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE IMPLIED WARRANTIES OR CONDITIONS OF
MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. IN NO EVENT SHALL ASUS, ITS
DIRECTORS, OFFICERS, EMPLOYEES OR AGENTS BE LIABLE FOR ANY INDIRECT, SPECIAL,
INCIDENTAL, OR CONSEQUENTIAL DAMAGES (INCLUDING DAMAGES FOR LOSS OF PROFITS,
LOSS OF BUSINESS, LOSS OF USE OR DATA, INTERRUPTION OF BUSINESS AND THE LIKE),
EVEN IF ASUS HAS BEEN ADVISED OF THE POSSIBILITY OF SUCH DAMAGES ARISING FROM ANY
DEFECT OR ERROR IN THIS MANUAL OR PRODUCT.
SPECIFICATIONS AND INFORMATION CONTAINED IN THIS MANUAL ARE FURNISHED FOR
INFORMATIONAL USE ONLY, AND ARE SUBJECT TO CHANGE AT ANY TIME WITHOUT NOTICE,
AND SHOULD NOT BE CONSTRUED AS A COMMITMENT BY ASUS. ASUS ASSUMES NO
RESPONSIBILITY OR LIABILITY FOR ANY ERRORS OR INACCURACIES THAT MAY APPEAR IN THIS
MANUAL, INCLUDING THE PRODUCTS AND SOFTWARE DESCRIBED IN IT.
Products and corporate names appearing in this manual may or may not be registered trademarks or
copyrights of their respective companies, and are used only for identication or explanation and to the
owners’ benet, without intent to infringe.

iii
Contents
Safety information...................................................................................................... iv
About this guide.......................................................................................................... v
Package contents....................................................................................................... vi
PRIME H610M-R D4 specications summary.......................................................... vi
Chapter 1 Product Introduction
1.1 Before you proceed...................................................................................... 1-1
1.2 Motherboard overview ................................................................................. 1-1
1.3 Central Processing Unit (CPU).................................................................... 1-7
1.4 System memory............................................................................................ 1-9
Chapter 2 BIOS Information
2.1 Knowing BIOS............................................................................................... 2-1
2.2 BIOS Setup program .................................................................................... 2-2
2.3 ASUS EZ Flash 3........................................................................................... 2-3
2.4 ASUS CrashFree BIOS 3.............................................................................. 2-4
Appendix
Notices ..................................................................................................................... A-1
Warranty................................................................................................................... A-6
ASUS contact information...................................................................................... A-8
Service and Support ............................................................................................... A-8

iv
Safety information
Electrical safety
• To prevent electrical shock hazard, disconnect the power cable from the electrical outlet
before relocating the system.
• When adding or removing devices to or from the system, ensure that the power cables
for the devices are unplugged before the signal cables are connected. If possible,
disconnect all power cables from the existing system before you add a device.
• Before connecting or removing signal cables from the motherboard, ensure that all power
cables are unplugged.
• Seek professional assistance before using an adapter or extension cord. These devices
could interrupt the grounding circuit.
• Ensure that your power supply is set to the correct voltage in your area. If you are not
sure about the voltage of the electrical outlet you are using, contact your local power
company.
• If the power supply is broken, do not try to x it by yourself. Contact a qualied service
technician or your retailer.
Operation safety
• Before installing the motherboard and adding components, carefully read all the manuals
that came with the package.
• Before using the product, ensure all cables are correctly connected and the power cables
are not damaged. If you detect any damage, contact your dealer immediately.
• To avoid short circuits, keep paper clips, screws, and staples away from connectors,
slots, sockets and circuitry.
• Avoid dust, humidity, and temperature extremes. Do not place the product in any area
where it may be exposed to moisture.
• Place the product on a stable surface.
• If you encounter technical problems with the product, contact a qualied service
technician or your retailer.
• Your motherboard should only be used in environments with ambient temperatures
between 0°C and 40°C.

v
About this guide
This user guide contains the information you need when installing and conguring the
motherboard.
How this guide is organized
This guide contains the following parts:
• Chapter 1: Product Introduction
This chapter describes the features of the motherboard and the new technology it
supports. It includes descriptions of the switches, jumpers, and connectors on the
motherboard.
• Chapter 2: BIOS Information
This chapter tells how to boot into the BIOS and upgrade BIOS using the EZ Flash
Utility.
Where to nd more information
Refer to the following sources for additional information and for product and software
updates.
1. ASUS website
The ASUS website provides updated information on ASUS hardware and software
products. Refer to the ASUS contact information.
2. Optional documentation
Your product package may include optional documentation, such as warranty yers,
that may have been added by your dealer. These documents are not part of the
standard package.
Conventions used in this guide
To ensure that you perform certain tasks properly, take note of the following symbols used
throughout this manual.
CAUTION: Information to prevent damage to the components and injuries to
yourself when trying to complete a task.
IMPORTANT: Instructions that you MUST follow to complete a task.
NOTE: Tips and additional information to help you complete a task.

vi
CPU
Intel®Socket LGA1700 for 12th Gen Intel®Core™, Pentium®Gold and
Celeron®Processors*
Supports up to Intel®65W CPU
Supports Intel®Turbo Boost Technology 2.0 and Intel®Turbo Boost Max
Technology 3.0**
* Refer to www.asus.com for CPU support list.
** Intel®Turbo Boost Max Technology 3.0 support depends on the CPU types.
Chipset Intel®H610 Chipset
Memory
2 x DIMM, Max. 64GB, DDR4 3200/3000/2933/2800/2666/2400/2133 Non-
ECC, Un-buffered Memory*
Dual Channel Memory Architecture
Supports Intel® Extreme Memory Prole (XMP)
* Actual memory data rate depends on the CPU types and DRAM modules, for
more information refer to www.asus.com for memory support list.
Graphics
1 x D-Sub port
1 x DVI-D port
1 x HDMI®port**
* Graphics specications may vary between CPU types. Please refer to www.
intel.com for any updates.
** Supports 4K@60Hz as specied in HDMI 2.1.
Expansion Slots
Intel®12th Gen Processors
1 x PCIe 4.0 x16 slot
Intel®H610 Chipset
1 x PCIe 3.0 x1 slot
Storage
Total supports 1 x M.2 slot and 4 x SATA 6Gb/s ports
Intel®H610 Chipset
M.2 slot (Key M), type 2242/2260/2280 (supports PCIe 3.0 x4 mode)
4 x SATA 6Gb/s ports
Ethernet 1 x Realtek 1Gb Ethernet
Package contents
Check your motherboard package for the following items.
Motherboard 1 x PRIME H610M-R D4 motherboard
Cables 2 x SATA 6Gb/s cables
Miscellaneous 1 x I/O Shield
1 x M.2 Anchor
Installation Media 1 x Support DVD
Documentation 1 x User guide
If any of the above items is damaged or missing, contact your retailer.
PRIME H610M-R D4 specications summary
(continued on the next page)

vii
PRIME H610M-R D4 specications summary
USB
Rear USB (Total 4 ports)
2 x USB 3.2 Gen 1 ports (2 x Type-A)
2 x USB 2.0 ports (2 x Type-A)
Front USB (Total 6 ports)
1 x USB 3.2 Gen 1 header supports additional 2 USB 3.2 Gen 1 ports
2 x USB 2.0 headers support additional 4 USB 2.0 ports
Audio
Realtek 7.1 Surround Sound High Denition Audio CODEC*
- Supports: Jack-detection, Multi-streaming, Front Panel Jack-retasking
- Supports up to 24-Bit/192kHz playback
Audio Features
- Audio Shielding
- Premium audio capacitors
- Dedicated audio PCB layers
* A chassis with an HD audio module in the front panel is required to support 7.1
Surround Sound audio output.
Back Panel I/O Ports
2 x USB 3.2 Gen 1 ports (2 x Type-A)
2 x USB 2.0 ports (2 x Type-A)
1 x D-Sub port
1 x DVI-D port
1 x HDMI®port
1 x Realtek 1Gb Ethernet port
3 x Audio jacks
1 x PS/2 Keyboard (purple) port
1 x PS/2 Mouse (green) port
Internal I/O
Connectors
Fan and Cooling related
1 x 4-pin CPU Fan header
1 x 4-pin Chassis Fan header
Power related
1 x 24-pin Main Power connector
1 x 4-pin +12V Power connector
Storage related
1 x M.2 slot (Key M)
4 x SATA 6Gb/s ports
USB
1 x USB 3.2 Gen 1 header supports additional 2 USB 3.2 Gen 1 ports
2 x USB 2.0 headers support additional 4 USB 2.0 ports
Miscellaneous
1 x Clear CMOS header
1 x Chassis Intrusion header
1 x COM Port header
1 x Front Panel Audio header (AAFP)
1 x LPT header
1 x Speaker header
1 x SPI TPM header (14-1 pin)
1 x 10-1 pin System Panel header
(continued on the next page)

viii
PRIME H610M-R D4 specications summary
Special Features
ASUS 5X PROTECTION III
- DIGI+ VRM
- LANGuard
- Overvoltage Protection
- SafeSlot Core
- Stainless-Steel Back I/O
ASUS Q-Design
- Q-DIMM
- Q-Slot
ASUS Thermal Solution
- Aluminum heatsink design
Software
Features
ASUS Exclusive Software
Armoury Crate
AI Suite 3
- Performance And Power Saving Utility
TurboV EVO
EPU
DIGI+ VRM
ASUS CPU-Z
Norton Anti-virus software (Free Trial version)
WinRAR
UEFI BIOS
ASUS EZ DIY
- ASUS CrashFree BIOS 3
- ASUS EZ Flash 3
- ASUS UEFI BIOS EZ Mode
BIOS 128 Mb Flash ROM, UEFI AMI BIOS
Manageability WOL by PME, PXE
Operating System Windows®11 64-bit,
Windows®10 64-bit
Form Factor mATX Form Factor
8.9 inch x 7.6 inch (22.6 cm x 19.3 cm)
Specications are subject to change without notice. Please refer to the ASUS website for the
latest specications.

ASUS PRIME H610M-R D4 1-1
Product Introduction
1
1.1 Before you proceed
Take note of the following precautions before you install motherboard components or change
any motherboard settings.
• Unplug the power cord from the wall socket before touching any component.
• Before handling components, use a grounded wrist strap or touch a safely grounded
object or a metal object, such as the power supply case, to avoid damaging them due
to static electricity.
• Before you install or remove any component, ensure that the ATX power supply is
switched off or the power cord is detached from the power supply. Failure to do so
may cause severe damage to the motherboard, peripherals, or components.
1.2 Motherboard overview
Place this
side towards
the rear of the
chassis
ATX_12V
PCIEX16(G4)
PCIEX1(G3)
SPEAKER
TPM
128Mb
BIOS
CLRTC
F_PANEL
LPT
USB78 USB914
COM_DEBUG
CHASSIS
COM
U32G1_12
AAFP
ATX_PWR
CPU_FAN
BATTERY
CHA_FAN
Super
I/O
22.6cm(8.9in)
DDR4 DIMM_A1 (64bit, 288-pin module)
2280 2260 2242
DDR4 DIMM_B1 (64bit, 288-pin module)
AUDIO
KBMS
DVI
VGA
LAN_USB_56
U32G1_34
HDMI
19.3cm(7.6in)
SATA6G_2 SATA6G_3 SATA6G_4
SATA6G_1
Intel®
H610
M.2(SOCKET3)
M.2(SOCKET3)
Audio
Codec
DIGI+
VRM
LGA1700
Ethernet
PCIE SATA
3.0 X4 X
65 1 2 4
159 71013
8
16
17
5
4
3
12
14 11
7
Unplug the power cord before installing or removing the motherboard. Failure to do so can
cause you physical injury and damage motherboard components.
The pin denitions in this chapter are for reference only. The pin names depend on the
location of the header/jumper/connector.

1-2 Chapter 1: Product Introduction
1.2.1 Layout contents
1. CPU socket
The motherboard comes with a LGA1700 Socket designed for 12th Gen Intel®Core™,
Pentium®Gold and Celeron®Processors.
• Supports up to Intel®65W CPU
• For more details, refer to Central Processing Unit (CPU).
2. DDR4 DIMM slots
The motherboard comes with Dual Inline Memory Modules (DIMM) slots designed for DDR4
(Double Data Rate 4) memory modules.
For more details, refer to System memory.
3. Expansion slots
This motherboard supports one PCIe x16 graphics card and one PCIe 3.0 x1 network card,
SCSI card or other card that complies with the PCI Express specications.
4. Fan headers
The Fan headers allow you to connect fans to cool the system.
5. Power connectors
These Power connectors allow you to connect your motherboard to a power supply. The
power supply plugs are designed to t in only one orientation. Find the proper orientation and
push down rmly until the power supply plugs are fully inserted.
Ensure to connect the 4-pin power plug.
• We recommend that you use a PSU with a higher power output when conguring a
system with more power-consuming devices. The system may become unstable or
may not boot up if the power is inadequate.
• If you are uncertain about the minimum power supply requirement for your system, we
recommend you to refer to online resources for Power Supply Wattage Calculator.
6. M.2 slot (Key M)
The M.2 slot allows you to install an M.2 device such as an M.2 SSD module.
M.2 slot (Key M), type 2242/2260/2280 (supports PCIe 3.0 x4 mode).
The M.2 SSD module is purchased separately.
7. SATA 6Gb/s ports
The SATA 6Gb/s ports allow you to connect SATA devices such as optical disc drives and
hard disk drives via SATA cables.
FAN PWM
FAN IN
FAN PWR
GND
FAN PWM
FAN IN
FAN PWR
GND

ASUS PRIME H610M-R D4 1-3
8. USB 3.2 Gen 1 header
The USB 3.2 Gen 1 header allows you to connect a USB 3.2 Gen
1 module for additional USB 3.2 Gen 1 ports. The USB 3.2 Gen 1
header provides data transfer speed of up to 5 Gb/s.
The USB 3.2 Gen 1 module is purchased separately.
9. USB 2.0 headers
The USB 2.0 headers allow you to connect a USB module for additional USB
2.0 ports. The USB 2.0 headers provide data transfer speed of up to 480 Mb/s.
DO NOT connect a 1394 cable to the USB connectors. Doing so will
damage the motherboard!
The USB 2.0 module is purchased separately.
10. Chassis Intrusion header (4-1 pin CHASSIS)
This header is for a chassis-mounted intrusion detection sensor or switch.
Connect one end of the chassis intrusion sensor or switch cable to this
connector. The chassis intrusion sensor or switch sends a high-level signal to
this connector when a chassis component is removed or replaced. The signal
is then generated as a chassis intrusion event.
11. Clear CMOS header
This header allows you to clear the CMOS RTC RAM data of the system setup
information such as date, time, and system passwords.
To erase the RTC RAM:
1. Turn OFF the computer and unplug the power cord.
2. Use a metal object such as a screwdriver to short the two pins.
3. Plug the power cord and turn ON the computer.
4. Hold down the <Del> key during the boot process and enter BIOS Setup to re-
enter data.
If the steps above do not help, remove the onboard battery and short the two pins again to
clear the CMOS RTC RAM data. After clearing the CMOS, reinstall the battery.
12. COM Port header
This header is for a serial (COM) port. Connect the serial port module cable
to this header, then install the module to a slot opening at the back of the
system chassis.
The COM port module is purchased separately.
USB3+5V
IntA_P1_SSRX-
IntA_P1_SSRX+
GND
IntA_P1_SSTX-
IntA_P1_SSTX+
GND
IntA_P1_D-
IntA_P1_D+
GND
PIN 1
USB3+5V
IntA_P2_SSRX-
IntA_P2_SSRX+
GND
IntA_P2_SSTX-
IntA_P2_SSTX+
GND
IntA_P2_D-
IntA_P2_D+
PIN 1
USB+5V USB_P9- USB_P9+ GND NC
USB+5V
USB_P14-
USB_P14+
GND
+5VSB_MB Chassis Signal GND
CHASSIS
CLRTC
+3V_BAT GND
PIN 1
PIN 1
DCD
TXD
GND
RTS
RI
RXD
DTR
DSR
CTS
COM

1-4 Chapter 1: Product Introduction
13. Front Panel Audio header
This header is for a chassis-mounted front panel audio I/O module that
supports HD audio standard. Connect one end of the front panel audio
I/O module cable to this header.
• We recommend that you connect a high-denition front panel
audio module to this header to avail of the motherboard’s high-
denition audio capability.
• If you want to connect a high-denition front panel audio module
to this header, set the Front Panel Type item in the BIOS Setup
to [HD Audio]. By default, this header is set to [HD Audio].
14. LPT header
The LPT (Line Printing Terminal) header supports devices such as
a printer. LPT standardizes as IEEE 1284, which is the parallel port
interface on IBM PC-compatible computers.
15. Speaker header
The 4-pin header is for the chassis-mounted system warning speaker. The
speaker allows you to hear system beeps and warnings.
16. 10-1 pin System Panel header
This header supports several chassis-mounted functions.
• System power LED (2-pin +PWR_LED-)
This 2-pin header is for the system power LED. Connect the chassis
power LED cable to this header. The system power LED lights up
when you turn on the system power, and blinks when the system is
in sleep mode.
• Hard disk drive activity LED (2-pin +HDD_LED-)
This 2-pin header is for the HDD Activity LED. Connect the HDD
Activity LED cable to this header. The HDD LED lights up or ashes
when data is read from or written to the HDD.
• Power button/Soft-off button (2-pin PWR_BTN)
This header is for the system power button.
• Reset button (2-pin RESET)
This 2-pin header is for the chassis-mounted reset button for system reboot without
turning off the system power.
AAFP
AGND NC SENSE1_RETUR SENSE2_RETUR
PORT1 L
PORT1 R PORT2 R
SENSE_SEND
PORT2 L
HD-audio-compliant
pin definition
PIN 1
O_LPT_XSTB#_R
O_LPT_XPD0_R O_LPT_XPD1_R O_LPT_XPD2_R O_LPT_XPD3_R O_LPT_XPD4_R O_LPT_XPD5_R O_LPT_XPD6_R O_LPT_XPD7_R O_LPT_ACK#_R
O_LPT_BUSY_R
O_LPT_PE_R
O_LPT_SLCT_R
O_LPT_XAFD#_R O_LPT_ERROR#_R O_LPT_XINIT#_R O_LPT_XSLIN#_R GND GND GND GND GND GND GND GND
SPEAKER
+5V GND GND Speaker Out
PIN 1
PIN 1
PWR_BTN
PWR_LED+ PWR_LED- PWR GND
HDD_LED+
HDD_LED-
Ground
HWRST#
(NC)
F_PANEL
+PWR_LED-
+HDD_LED- RESET

ASUS PRIME H610M-R D4 1-5
1.2.2 Rear panel connectors
1
8 10 11
3 4 5
96
2
7
17. SPI TPM header
This header supports a Trusted Platform Module (TPM)
system with a Serial Peripheral Interface (SPI), allowing
you to securely store keys, digital certicates, passwords
and data. A TPM system also enhances network security,
protects digital identities, and ensures platform integrity.
The SPI TPM module is purchased separately.
TPM
PIN 1
VCCSPI
S_PLTRST#
F2_SPI_CS1#_R
+3V_SPI
F_SPI_CS0#_R
T_SPI_MISO
F_SPI_HOLD#_R
S_SPI_TPM_IRQ#
S_SPI_TPM_CS2#
F_BIOS_WP#_R
GND
T_SPI_CLK
T_SPI_MOSI
1. PS/2 mouse (green) port. This port is for a PS/2 mouse.
2. Video Graphics Adapter (VGA) port. This 15-pin port is for a VGA monitor or other
VGA-compatible devices.
3. Ethernet port. This port allows Gigabit connection to a Local Area Network (LAN)
through a network hub. Refer to the table below for the Ethernet port LED indications.
Realtek 1Gb Ethernet port LED indications
Speed LED
Status Description
OFF 10 Mbps connection
ORANGE 100 Mbps connection
GREEN 1 Gbps connection
ACT/LINK
LED
SPEED
LED
Ethernet port
Activity Link LED
Status Description
OFF No link
ORANGE Linked
BLINKING Data activity
4. Line In port (light blue). This port connects the tape, CD, DVD player, or other audio
sources.
5. Line Out port (lime). This port connects a headphone or a speaker. In 4-channel,
5.1-channel, and 7.1-channel congurations, the function of this port becomes Front
Speaker Out.

1-6 Chapter 1: Product Introduction
6. PS/2 keyboard (purple) port. This port is for a PS/2 keyboard.
7. DVI-D port. This port is for any DVI-D compatible device.
DVI-D can not be converted to output from RGB Signal to CRT and is not compatible with
DVI-I.
8. HDMI®port. This port is for a High-Denition Multimedia Interface (HDMI®) connector,
and is HDCP compliant allowing playback of HD DVD, Blu-ray, and other protected
content.
9. USB 3.2 Gen 1 (up to 5Gbps) ports. These 9-pin Universal Serial Bus (USB) ports
connect to USB 3.2 Gen 1 devices.
10. USB 2.0 ports. These 4-pin Universal Serial Bus (USB) ports are for USB 2.0 devices.
11. Microphone port (pink). This port connects a microphone.
Refer to the audio conguration table below for the function of the audio ports in 2, 4, 5.1,
or 7.1-channel conguration.
Audio 2, 4, 5.1 or 7.1-channel conguration
Port Headset
2-channel 4-channel 5.1-channel 7.1-channel
Light Blue (Rear panel) Line In Rear Speaker Out Rear Speaker Out Rear Speaker Out
Lime (Rear panel) Line Out Front Speaker Out Front Speaker Out Front Speaker Out
Pink (Rear panel) Mic In Mic In Bass/Center Bass/Center
Lime (Front panel) — — — Side Speaker Out*/
Headphone
Pink (Front panel) — — — Mic In*/
Side Speaker Out
* Multi-streaming is disabled by default, and the Lime (front panel) jack may be used as Side Speaker Out. If multi-
streaming is enabled, the Lime (front panel) jack will support headphone, and Pink (front panel) jack will support
Side Speaker Out.
To congure a 7.1-channel audio output:
Use a chassis with HD audio module in the front panel to support a 7.1-channel audio
output.

ASUS PRIME H610M-R D4 1-7
1.3 Central Processing Unit (CPU)
The motherboard comes with a LGA1700 Socket designed for 12th Gen
Intel®Core™, Pentium®Gold and Celeron®Processors.
Unplug all power cables before installing the CPU.
• Supports up to Intel®65W CPU
• Ensure that you install the correct CPU designed for LGA1700 socket only. DO NOT
install a CPU designed for LGA1155, LGA1156, LGA1151, and LGA1200 sockets on
the LGA1700 socket.
• ASUS will not cover damages resulting from incorrect CPU installation/removal,
incorrect CPU orientation/placement, or other damages resulting from negligence by
the user.
LGA1700
Installing the CPU
Take caution when lifting the load
lever, ensure to hold onto the load
lever when releasing the load
lever. Letting go of the load lever
immediately after releasing it may
cause the load lever to spring
back and cause damage to your
motherboard.

1-8 Chapter 1: Product Introduction

ASUS PRIME H610M-R D4 1-9
1.4 System memory
This motherboard comes with two Double Data Rate 4 (DDR4) Dual Inline Memory Module
(DIMM) sockets. The gure illustrates the location of the DDR4 DIMM sockets:
Channel Sockets
Channel A DIMM_A1
Channel B DIMM_B1
DIMM_A1
DIMM_B1
• You may install varying memory sizes in Channel A and Channel B. The system
maps the total size of the lower-sized channel for the dual-channel conguration. Any
excess memory from the higher-sized channel is then mapped for single-channel
operation.
• A DDR4 memory module is notched differently from a DDR, DDR2, or DDR3 module.
DO NOT install a DDR, DDR2, or DDR3 memory module to the DDR4 slot.
• The default memory operation frequency is dependent on its Serial Presence Detect
(SPD), which is the standard way of accessing information from a memory module.
Under the default state, some memory modules for overclocking may operate at a
lower frequency than the vendor-marked value.
• For system stability, use a more efcient memory cooling system to support a full
memory load.
• Always install DIMMs with the same CAS latency. For optimal compatibility, we
recommend that you install memory modules of the same version or date code (D/C)
from the same vendor. Check with the retailer to get the correct memory modules.
• Actual memory data rate depends on the CPU types and DRAM modules, for more
information refer to www.asus.com for the Memory QVL (Qualied Vendors Lists).
Recommended memory congurations
DIMM_B1 DIMM_A1
DIMM_A1
DIMM_B1

1-10 Chapter 1: Product Introduction
Installing a DIMM
1 2
B
A
A
To remove a DIMM
BA

ASUS PRIME H610M-R D4 2-1
BIOS Information
2
2.1 Knowing BIOS
The new ASUS UEFI BIOS is a Unied Extensible Interface that complies with UEFI
architecture, offering a user-friendly interface that goes beyond the traditional keyboard-
only BIOS controls to enable a more exible and convenient mouse input. You can easily
navigate the new UEFI BIOS with the same smoothness as your operating system. The
term “BIOS” in this user manual refers to “UEFI BIOS” unless otherwise specied.
BIOS (Basic Input and Output System) stores system hardware settings such as storage
device conguration, overclocking settings, advanced power management, and boot
device conguration that are needed for system startup in the motherboard CMOS. In
normal circumstances, the default BIOS settings apply to most conditions to ensure
optimal performance. DO NOT change the default BIOS settings except in the following
circumstances:
• An error message appears on the screen during the system bootup and requests you
to run the BIOS Setup.
• You have installed a new system component that requires further BIOS settings or
update.
Inappropriate BIOS settings may result to instability or boot failure. We strongly
recommend that you change the BIOS settings only with the help of a trained service
personnel.
BIOS settings and options may vary due to different BIOS release versions. Please refer to
the latest BIOS version for settings and options.
For more information on BIOS congurations, please refer to
https://www.asus.com/support, or download the BIOS manual by
scanning the QR code.

2-2 Chapter 2: BIOS Information
2.2 BIOS Setup program
Use the BIOS Setup to update the BIOS or congure its parameters. The BIOS screens
include navigation keys and brief onscreen help to guide you in using the BIOS Setup
program.
Entering BIOS at startup
To enter BIOS Setup at startup, press <Delete> or <F2> during the Power-On Self Test
(POST). If you do not press <Delete> or <F2>, POST continues with its routines.
Entering BIOS Setup after POST
To enter BIOS Setup after POST:
• Press <Ctrl>+<Alt>+<Delete> simultaneously.
• Press the reset button on the system chassis.
• Press the power button to turn the system off then back on. Do this option only if you
failed to enter BIOS Setup using the rst two options.
After doing either of the three options, press <Delete> key to enter BIOS.
• Ensure that a USB mouse is connected to your motherboard if you want to use the
mouse to control the BIOS Setup program.
• If the system becomes unstable after changing any BIOS setting, load the default
settings to ensure system compatibility and stability. Select the Load Optimized
Defaults item under the Exit menu or press hotkey <F5>.
• If the system fails to boot after changing any BIOS setting, try to clear the CMOS and
reset the motherboard to the default value.
• The BIOS Setup program does not support Bluetooth devices.
BIOS menu screen
The BIOS Setup program can be used under two modes: EZ Mode and Advanced Mode.
You can change modes from Setup Mode in Boot menu or by pressing the <F7> hotkey.