Beckman Coulter AU2700 User manual

Beckman Coulter, Inc.
250 S. Kraemer Blvd.
Brea, CA 92821
AU2700®
Chemistry Analyzer
For In Vitro Diagnostic Use
Users Guide Vol. 1
BM0561V1
NOV 2009

Beckman Coulter, Inc.
250 S. Kraemer Blvd.
Brea, CA 92821
Copyright©2009 Beckman Coulter Inc.. All rights reserved. Printed in the United States of America.
AU2700® is a registered trademark of Beckman Coulter Corporation, Beckman Coulter Inc., or their afliated entities.
No part of this publication may be reproduced in any form or by any means without prior written permission of
Beckman Coulter Inc. While every precaution has been taken during document preparation, Beckman Coulter Inc.
assumes no responsibility for errors or omissions. Neither is any liability assumed for damages resulting from the use
of the information contained herein.
BECKMAN COULTER INC.
250 S. Kraemer Blvd.
Brea, CA 92821
This guide was written to comply with Clinical and Laboratory Standards Institute Protocols (CLSI) guidelines for
Clinical Laboratory Procedure Manuals; however, each laboratory may need to modify and/or add procedures to meet
the laboratory requirements of CLSI.
The AU2700® is ISO13485 certied. Design and production adheres to ISO13485 international quality standards.
The AU2700®has been tested and found to comply with the limits for a Class A digital device, pursuant to Part 15
of the FCC Rules. These limits are designed to provide reasonable protection against harmful interference when the
equipment is operated in a commercial environment. This equipment generates, uses, and can radiate radio frequency
energy. If the instrument is not installed and used in accordance with the instruction manual, harmful interference
to radio communications may result. Operation of this equipment in a residential area is likely to cause harmful
interference in which case the users will be required to correct the interference at their own expense.
FCC Warning: Changes or modications not expressly approved by the party responsible for compliance could void
the user’s authority to operate the equipment.

Automated Chemistry Analyzer
AU2700 User's Guide Contents -
1
May, 2001
Table of Contents
Main Contents
AU2700 User’s Guide
Volume I: Precautions, System Outline, Basic Operations, and Software
Document Change Notication Sheet ........................................ Behind Cover Page
Introduction...................................................................................................................i
Conventions for this Manual ........................................................................................................ii
Terms Used in This Manual .........................................................................................................ii
Notices on the Supplied Programs ............................................................................................. iii
Trademarks................................................................................................................................. iii
Warranty .....................................................................................................................................iv
Chapter A Precautions and Installation Environments
Introduction..................................................................................................................1
1. Safety Precautions................................................................................................2
2. Precautions on Use...........................................................................................A-5
3. Installation Environments ..............................................................................A-10
Installation Environment Conditions ......................................................................................A-10
Temperature and Humidity Conditions...................................................................................A-10
Installation Space Requirements........................................................................................... A-11
Power Source and Grounding ............................................................................................... A-11
Water Supply and Drainage...................................................................................................A-12
Installing a Deionizer .............................................................................................................A-13
Wiring and Piping...................................................................................................................A-13
4. List of Standard Accessories.........................................................................A-15
5. Analyzer Warning and Caution Labels..........................................................A-16
Chapter B System Outline
Introduction..............................................................................................................B-1
1. Outline of Functions .........................................................................................B-2
2. Conguration of System Components............................................................B-4
3. Outline of Screen Operations...........................................................................B-7
3.1 Keyboard Functions...............................................................................................................B-10
3.2 Using the Mouse....................................................................................................................B-13
3.3 Selecting Menus and Items ...................................................................................................B-14
3.4 Help Functions.......................................................................................................................B-21
4. Login/Logout Function ...................................................................................B-22
5. Description of Measure Modes ......................................................................B-23

2 Contents - Automated Chemistry Analyzer
AU2700 User's Guide
May, 2001
Chapter C Basic Operations
Introduction..............................................................................................................C-1
1. General Operating Procedures ........................................................................C-3
2. Preparing for Analysis ......................................................................................C-7
2.1 Starting the AU2700.................................................................................................................C-8
2.2 Starting the ISE .....................................................................................................................C-12
2.3 Performing Calibrations and a Reagent Blank.......................................................................C-15
2.3.1 Performing a Calibration and Reagent Blank on the Analyzer...................................C-16
2.3.2 Calibration Analysis with Barcodes............................................................................C-17
2.3.3 Performing a Reagent Blank or Calibration on the STAT Table.................................C-18
2.3.4 Programming Advanced Calibration ..........................................................................C-19
2.3.5 Programming Auto Calibration...................................................................................C-20
2.4 Quality Control Analysis.........................................................................................................C-22
2.4.1 Requisitioning QC Samples.......................................................................................C-22
2.4.2 QC Analysis with Barcodes........................................................................................C-23
2.4.3 Performing QC on the STAT Table.............................................................................C-24
2.4.4 Performing Auto-calibration and QC on the STAT Table............................................C-25
2.4.5 Programming Auto QC ..............................................................................................C-26
2.5 Starting Normal Analysis........................................................................................................C-27
2.5.1 Entering Individual Requisitions (Routine, Emergency and Priority STATs) ..............C-28
2.5.2 HowtoRequisitionbyaProle(Routine,EmergencyandPrioritySTATs) ...............C-30
2.5.3 Entering Group (Batch) Requisitions (Routine, Emergency & Priority STATS) .........C-31
2.5.4 Performing Priority STAT Analysis .............................................................................C-32
2.5.5 Downloading Requisitions from a Host Computer.....................................................C-34
2.5.6 Real-time Downloading of Requisitions from a Host Computer.................................C-35
2.6 Preparing Samples and Racks ..............................................................................................C-36
2.7 Placing Racks on the Analyzer ..............................................................................................C-52
2.8 Daily Maintenance and Inspection.........................................................................................C-54
2.8.1 Periodic Maintenance ................................................................................................C-54
2.8.2 Consumables.............................................................................................................C-56
2.8.3 Changing Reagents...................................................................................................C-57
2.8.4 How to Set (Fix) a Reagent Position..........................................................................C-61
2.8.5 Adding Wash Solution ...............................................................................................C-62
2.8.6 How to Place the Sample Pre-dilution Bottle.............................................................C-63
3. Starting Analysis .............................................................................................C-65
4. Obtaining Results............................................................................................C-67
4.1 Checking Results...................................................................................................................C-68
4.2 Checking Quality Control ......................................................................................................C-69
4.3 Performing a Repeat Run......................................................................................................C-74
4.3.1 How to Print a Repeat Run Work List........................................................................C-75
4.3.2 How to Modify the Repeat Work List: ........................................................................C-76
4.3.3 How to Perform an Auto-Repeat Run ........................................................................C-77
4.3.4 How to Perform a Manual Repeat Run......................................................................C-79
4.3.5 How to Perform a Manual Repeat Run Using the STAT Table ..................................C-80
4.3.6 Reporting Repeat Results or Original Results...........................................................C-83
4.4 Editing Results.......................................................................................................................C-85
4.5 Correcting Results .................................................................................................................C-87
4.6 Printing Edited or Corrected Data..........................................................................................C-88
4.7 How to Reprint Reagent Blank, Calibrator, QC and Patient Data..........................................C-89
4.8 Saving Parameters and Data to a Floppy Disk......................................................................C-90
5. Finishing Analysis...........................................................................................C-91
6. As-Needed Tasks.............................................................................................C-93
6.1 Checking Analysis Conditions................................................................................................C-95
6.2 Processing Priority/Emergency Samples...............................................................................C-97
6.2.1 Using the STAT Table: One Touch Mode ...................................................................C-98
6.2.2 Using the STAT Table: Normal Analysis Mode........................................................C-100
6.2.3 Using the Red Rack.................................................................................................C-103
6.3 Performing a Stop or an Emergency Stop During Analysis .................................................C-105
6.4 Pausing Analysis..................................................................................................................C-107
6.5 Stopping the Rack Feed Unit...............................................................................................C-108

Automated Chemistry Analyzer
AU2700 User's Guide Contents -
3
May, 2001
6.6 CreatingaNewProle.........................................................................................................C-109
6.7 Changing QC Ranges..........................................................................................................C-110
6.8 Changing Calibrator Set Points ........................................................................................... C-111
6.9 Turning On/Off the Sample ID Barcode Reader: .................................................................C-112
6.10 Programming the Auto Power On ........................................................................................C-113
6.11 Creating a User Menu..........................................................................................................C-114
6.12 Standby Mode......................................................................................................................C-115
6.13 Programming a New Test ....................................................................................................C-116
7. Operation Guide. ...........................................................................................C-121
Chapter D Software
Introduction..............................................................................................................D-1
1. Using System Status.........................................................................................D-5
1.1 About System Status ...............................................................................................................D-6
1.2 Performing a W1, W2, or Photocal, and using the One Touch Mode ......................................D-7
1.3 Reagent Status........................................................................................................................D-8
1.4 ISE Status .............................................................................................................................D-15
1.5 Analyzer (ANL) Status ...........................................................................................................D-19
1.6 Cuvette Status .......................................................................................................................D-22
1.7 Data Display ..........................................................................................................................D-24
1.8 Alarm List...............................................................................................................................D-26
1.9 Data Processor (DPR) Status................................................................................................D-28
1.10 STAT Table Status ................................................................................................................D-29
2. Routine Menu ..................................................................................................D-31
2.1 Start Conditions .....................................................................................................................D-32
2.2 Test Requisition .....................................................................................................................D-35
2.2.1 Normal Analysis.........................................................................................................D-35
2.2.2 Repeat Analysis........................................................................................................D-39
2.2.3 Quality Control...........................................................................................................D-43
2.2.4 Calibration .................................................................................................................D-45
2.2.5 Retrieve Repeat Data ................................................................................................D-47
2.3 Reaction Monitor....................................................................................................................D-49
2.4 Calibration Monitor.................................................................................................................D-55
2.4.1 Calibration Curve.......................................................................................................D-55
2.4.2 Calibration Trace........................................................................................................D-58
2.4.3 Reagent Blank Monitor ..............................................................................................D-60
2.5 Photocal Monitor....................................................................................................................D-62
2.6 QC Monitor ............................................................................................................................D-64
2.6.1 Daily Control ..............................................................................................................D-65
2.6.2 Day-to-Day Control....................................................................................................D-68
2.6.3 Twin Plot ...................................................................................................................D-70
2.6.4 Data Edit (QC Monitor) ..............................................................................................D-72
2.7 Data Management .................................................................................................................D-75
2.7.1 Data Edit ...................................................................................................................D-75
2.7.2 Data Correction..........................................................................................................D-77
2.7.3 RepeatDataVerication ............................................................................................D-80
2.8 Data Report ...........................................................................................................................D-81
2.8.1 Report........................................................................................................................D-81
2.8.2 Data List.....................................................................................................................D-83
2.8.3 Online ........................................................................................................................D-84
3. Parameter Menu Operations ..........................................................................D-87
3.1 Common Test Parameters .....................................................................................................D-88
3.1.1 Test Name..................................................................................................................D-88
3.1.2 Prole........................................................................................................................D-90
3.1.3 Round .......................................................................................................................D-91
3.2 SpecicTestParameters ......................................................................................................D-93
3.3 Inter-Related Tests.................................................................................................................D-99
3.3.1 Calculated Tests ........................................................................................................D-99
3.3.2 Checked Tests .........................................................................................................D-101
3.3.3 Sample Blank ..........................................................................................................D-103
3.4 Repeat Parameters..............................................................................................................D-104
3.4.1 Repeat Common......................................................................................................D-104

4 Contents - Automated Chemistry Analyzer
AU2700 User's Guide
May, 2001
3.4.2 RepeatSpecic........................................................................................................D-106
3.5 Quality Control ....................................................................................................................D-108
3.5.1 QC Common............................................................................................................D-108
3.5.2 QCSpecic.............................................................................................................. D-111
3.5.3 STAT Table QC ........................................................................................................D-113
3.6 Calibration............................................................................................................................D-116
3.6.1 Calibrator .................................................................................................................D-116
3.6.2 CalibrationSpecic..................................................................................................D-119
3.6.3 STAT Table Calibration ............................................................................................D-128
3.7 Online .................................................................................................................................D-131
3.7.1 Protocol....................................................................................................................D-132
3.7.2 Test No. ...................................................................................................................D-134
3.8 Format ................................................................................................................................D-135
3.8.1 Printer ....................................................................................................................D-135
3.8.2 Requisition Format...................................................................................................D-137
3.8.3 Report Format..........................................................................................................D-139
3.8.4 List Format...............................................................................................................D-142
3.9 Special.................................................................................................................................D-143
3.9.1 Contamination Parameters .....................................................................................D-143
3.9.2 Data Check Parameters ..........................................................................................D-146
3.10 System.................................................................................................................................D-147
3.10.1 Option ......................................................................................................................D-147
3.10.2 System ....................................................................................................................D-148
3.10.3 Auto Power On ........................................................................................................D-150
3.10.4 Password.................................................................................................................D-151
3.10.5 Login Name & Menu Level ......................................................................................D-152
3.10.6 User Menu ...............................................................................................................D-154
3.11 Comment Masters ...............................................................................................................D-156
4. Auxiliary Menu Operations...........................................................................D-157
4.1 Data Statistics......................................................................................................................D-158
4.2 Correlation Chart .................................................................................................................D-160
4.3 Histogram ............................................................................................................................D-162
4.4 Reagent Consumption.........................................................................................................D-164
4.5 Reagent Inventory ...............................................................................................................D-166
4.6 Parameters Management ....................................................................................................D-168
4.7 CalibrationVerication .........................................................................................................D-170
4.8 Standby Set .........................................................................................................................D-172
5. Maintenance Menu Operations ....................................................................D-173
5.1 Data Operation ....................................................................................................................D-174
5.1.1 FD Data Management ............................................................................................D-174
5.1.2 Set Date & Time ......................................................................................................D-176
5.1.3 Retrieve Database ..................................................................................................D-177
5.1.4 Off-line Output .........................................................................................................D-178
5.1.5 Modem.....................................................................................................................D-180
5.2 Analyzer Maintenance .........................................................................................................D-181
5.3 Consumable Management ..................................................................................................D-182
5.4 Periodic Maintenance ..........................................................................................................D-184
5.5 Maker Maintenance .............................................................................................................D-186
5.5.1 Program Version......................................................................................................D-186
5.5.2 Analyzer Diagnostics ...............................................................................................D-187
5.5.3 ISE Diagnostics .......................................................................................................D-192
5.5.4 Alarm Log ................................................................................................................D-195
5.5.5 File Management.....................................................................................................D-196
6. User Dened Menus......................................................................................D-197
Chapter E Software Menu Outline
1. Routine Menu Outline..............................................................................................................E-2
2. Parameter Menu Outline..........................................................................................................E-3
3. Auxiliary Menu Outline.............................................................................................................E-4
4. Maintenance Menu Outline......................................................................................................E-5
5. List of Screen Operations ........................................................................................................E-6

Automated Chemistry Analyzer
AU2700 User's Guide Introduction
i
March, 2000
Introduction
Thank you for purchasing the Beckman Coulter AU2700 automated chemistry analyzer. This
manual is intended for operators who have completed the training course offered by Beckman
Coulter, or operators who have been trained by those who have taken the Beckman Coulter
training course. Please read this manual carefully to understand instructions before operating
the system. The following information describes how this manual is structured:
Volume I: Precautions, System Outline, Basic Operations, and Software
Document Change Notication Sheet
This sheet lists all updates of the manual and corresponding software changes.
Chapter A Precautions and Installation Environments
This chapter describes necessary precautions and restrictions when using the system. It also
describes installation environments, standard accessories, and caution labels.
Chapter B System Outline
This chapter explains system features, system conguration, basic screen operation, and
system use.
Chapter C Basic Operations
This chapter is designed as a quick response section providing easy to follow basic operating
procedures. It contains the following information: easy steps to prepare for and start
analysis, how to obtain results and an operation owchart. It also describes other frequently
used procedures performed during daily routine operations.
Chapter D Software
This chapter describes the functions and operations related to each software screen.
Chapter E Software Menu Outline
This chapter outlines software menus.
Volume II: Maintenance, Error Flags, Troubleshooting, Specications, and Methods
Chapter F Maintenance
Chapter F provides detailed information about routine and as needed maintenance procedures.
Follow the procedures, and use the maintenance schedules provided in this section to track
maintenance. Performing scheduled maintenance is essential to the smooth operation of your
instrument.
Chapter G Error Flags
This chapter provides information on error ags that appear on your data printout as well as
fatal and nonfatal system errors.
Chapter H Troubleshooting
This chapter provides information on: using on-line help, determining the cause and solution
for abnormal data ags, and other general troubleshooting procedures.
Chapter I Specications
This chapter provides an outline of system operation during analysis and hardware
conguration descriptions of the analyzer. Is shows the piping diagram and major
specications of the system. This section also includes terminology denitions for the
AU2700.
Chapter J Methods
This chapter contains methodology sheets.

ii Introduction Automated Chemistry Analyzer
AU2700 User's Guide
March, 2000
Conventions for this Manual
This manual uses the following symbols.
lBrackets ([ and ]) are used to enclose the name of a software menu.
Example:
Select [Start Condition] from the [Routine] menu on the menu bar.
Terms Used in This Manual
The following terms are used when appropriate. Please pay attention to the following terms for
safe and proper use of this system.
Danger
Means severe injury to the operator or death can occur. Severe injury means loss of sight, wounds,
burns (high or low temperatures), electric shock, fractures, poisoning, and other after effects, or requires
a stay in a hospital or long-term treatment.
Warning
This is used when there is the possibility that severe injuries can occur.
Caution
Indicates that the operator should exercise care to prevent personal injury, physical damage, and serious
adverse effect on analysis results. It also indicates biohazards. Personal injury is referred to as injuries
such as mild burns and electric shock that do not require hospitalization or extensive medical attention.
Physical damage is referred to as damage to the analyzer, the building and its contents.
Instruction
Provides information on the correct operation of the instrument. If instructions are not followed, system
damage may occur because of incorrect operation.
Tip
Provides helpful tips on important information essential for understanding system operation and
functions.
See Also
Gives reference locations for further information on a topic.

Automated Chemistry Analyzer
AU2700 User's Guide Introduction
iii
February 4, 2004
Notices on the Supplied Programs
The CD-ROM and oppy disks that contain AU2700 software should be stored carefully in •
an
appropriate place.•
The programs may not be copied except for backup purposes.•
The programs may not be subjected to any reverse engineering including decompiling, •
disassembling, etc.
The programs, in part or in whole, may not be transferred, exchanged or leased to any party•
without the prior written consent of Beckman Coulter.
Trademarks
Corporate and product names that appear in this manual are their trademarks.
Change bars
Periodically, replacement pages for this document are sent to end users with updated
information. To help identify changes to affected pages, change bars appear in the outer page
margin next to the changed text or graphics. See the change bar next to this paragraph as an
example. Occassionally, change bars appear next to moved or reformatted information, but may
not appear when only the page number is different.

iv Introduction Automated Chemistry Analyzer
AU2700 User's Guide
February 4, 2004
Warranty
Beckman Coulter America Inc. - Diagnostic Systems Division (Beckman Coulter) warrants that
this Beckman Coulter clinical chemistry analyzer(s) or automated microplate system(s), and
related Beckman Coulter accessories (individually a "Product" and collectively the "Products")
will be free from defects in materials and workmanship under normal use and service for a
period of one (1) year from the date of installation. If any Product proves to be defective
within the foregoing warranty period, the customer must follow the procedure set forth below.
See "What to do when service is needed." Beckman Coulter, at its sole discretion, will repair,
replace, or adjust the defective Product, provided that Beckman Coulter investigation and
inspection disclose that (i) such defect developed under normal and proper use and (ii) the
Product is covered under this warranty. Repair, replacement, or adjustment of defective Products
shall be Beckman Coulter's sole obligation and the customer's sole remedy hereunder. Beckman
Coulter reserves the right to (i) use reconditioned, refurbished, and/or serviceable used parts
(tested to Beckman Coulter's quality assurance standards) for warranty repairs and (ii) make
any internal or external design and/or feature changes on or to its products without any liability
to incorporate such changes on or to the Products. Repair parts will be free from defects in
materials and workmanship under normal use and service for a period of ninety (90) days from
the date of installation.
Excluded from this warranty and not warranted by Beckman Coulter in any fashion, either
express, implied, or by statute, are:
a. products not manufactured by Beckman Coulter and/or not bearing the "Beckman
Coulter" brand label (the warranty coverage for products of other manufacturers, which
may be distributed by Beckman Coulter, is the responsibility of the manufacturers of such
products in accordance with the terms and duration of such manufacturers' warranties);
b. any Product which has been disassembled, repaired, tampered with, altered, changed,
or modied by persons other than Beckman Coulter's own authorized service personnel
unless repair by others is made with the written consent of Beckman Coulter;
c. defects or damage to the Products resulting from wear, tear, misuse, negligence, impact,
improper storage, nonperformance of scheduled operator and maintenance items, or use of
non-approved accessories, consumables, or supplies; and
d. supplies, reagents, calibrators, and consumables, which may be covered under a separate
warranty.
EXCEPT FOR THE LIMITED WARRANTY SET FORTH ABOVE, BECKMAN COULTER
MAKES NO AND DISCLAIMS ALL OTHER REPRESENTATIONS AND WARRANTIES,
WHETHER EXPRESS OR IMPLIED, CONCERNING THE PRODUCTS INCLUDING BUT
NOT LIMITED TO ANY IMPLIED WARRANTIES OR MERCHANTABILITY OR FITNESS
FOR A PARTICULAR PURPOSE, OR CONCERNING ANY PATENTS OR TECHNOLOGY
USED OR INCLUDED THEREIN. BECKMAN COULTER DOES NOT WARRANT THAT
SOFTWARE WILL BE ERROR-FREE AND/OR UNINTERRUPTED. IF ANY IMPLIED
WARRANTIES APPLY AS A MATTER OF LAW, THEY ARE LIMITED IN DURATION TO
THE LENGTH OF THIS WARRANTY. ALL GUARANTIES, WARRANTIES, CONDITIONS,
AND REPRESENTATIONS WHATSOEVER, EITHER EXPRESS OR IMPLIED, WHETHER
ARISING UNDER ANY STATUTE, LAW, COMMERCIAL USAGE OR OTHERWISE,
ARE HEREBY EXPRESSLY EXCLUDED. SOME STATES MAY NOT RECOGNIZE A
DISCLAIMER OR LIMITATION OF WARRANTIES AND/OR LIMITATION OF LIABILITY
SO THE ABOVE DISCLAIMER MAY NOT APPLY. THE CUSTOMER MAY ALSO HAVE
DIFFERENT AND/OR ADDITIONAL RIGHTS AND REMEDIES THAT VARY FROM STATE
TO STATE.
THE CUSTOMER ACKNOWLEDGES AND AGREES THAT BECKMAN COULTER SHALL
NOT BE RESPONSIBLE FOR ANY DAMAGES THAT THE CUSTOMER MAY INCUR
FROM DELAYED SHIPMENT, PRODUCT FAILURE, PRODUCT DESIGN, SELECTION,
OR PRODUCTION OR FROM ANY OTHER CAUSE, WHETHER LIABILITY IS ASSERTED
IN CONTRACT, TORT (INCLUDING NEGLIGENCE AND STRICT PRODUCT LIABILITY)
OR OTHERWISE. IN NO EVENT SHALL BECKMAN COULTER BE LIABLE FOR
ANY INDIRECT, INCIDENTAL, CONSEQUENTIAL OR SPECIAL DAMAGES OF ANY
KIND (INCLUDING WITHOUT LIMITATION LOSS OF PROFITS OR LOSS OF USE),

Automated Chemistry Analyzer
AU2700 User's Guide Introduction
v
March, 2000
WHETHER OR NOT BECKMAN COULTER SHALL BE OR SHOULD BE AWARE OF THE
POSSIBILITY OF SUCH POTENTIAL LOSS OR DAMAGE.
Representations and warranties made by any person, including dealers and representatives of
Beckman Coulter, which are inconsistent or in conict with the terms of this warranty, shall
not be binding upon Beckman Coulter unless reduced to writing and approved by an express
authorized ofcer of Beckman Coulter.
This warranty is the complete and exclusive statement of warranty which Beckman
Coulter agrees to provide with respect to the Products and it shall supersede all prior and
contemporaneous oral or written agreements, understandings, proposals, and communications
pertaining to the subject matter hereof.
WHO IS COVERED BY THIS WARRANTY
This warranty is exclusively for the benet of the original customer and cannot be transferred or
assigned.
WHAT TO DO WHEN SERVICE IS NEEDED
Please call 1-800-223-0130 and speak with Beckman Coulter's Technical Services Department.
INTERNATIONAL WARRANTY SERVICE
Outside of the United States and Canada, international warranty service is NOT available under
this warranty.
IF YOU HAVE QUESTIONS OR NEED HELP
If you have any questions or comments regarding the use or performance of your Products,
or service performed in the United States or Canada which has not been resolved to your
satisfaction; write directly to:
Beckman Coulter Inc.
Attention: Technical Services Manager

Automated Chemistry Analyzer
AU2700 User's Guide Chapter A - Precautions and Installation Environments
A-1
March, 2000
Chapter A
Precautions and Installation
Environments
Introduction
This chapter describes the precautions on system use, installation environments for proper
operation, standard accessories, warning and caution labels. To use the AU2700 safely and
to obtain the highest possible system performance, be sure to observe the precautions listed
on the following pages.
Chapter A Precautions and Installation Environments
Introduction...................................................................................................A-1
1. Safety Precautions .................................................................................A-2
2. Precautions on Use................................................................................A-5
3. Installation Environments....................................................................A-10
Installation Environment Conditions.................................................................................A-10
TemperatureandHumidityConditions..............................................................................A-10
InstallationSpaceRequirements ....................................................................................... A-11
Power Source and Grounding............................................................................................ A-11
WaterSupplyandDrainage ................................................................................................A-12
Installing a Deionizer...........................................................................................................A-13
WiringandPiping ................................................................................................................A-13
4. List of Standard Accessories ..............................................................A-15
5. Analyzer Warning and Caution Labels ...............................................A-16

A-2 Chapter A - Precautions and Installation Environments Automated Chemistry Analyzer
AU2700 User's Guide
March, 2000
1. Safety Precautions
To use your system safely and effectively, observe the following precautions. If the system
is used in a manner not specied by the manufacturer, the protection provided by the
system may be impaired.
Prevention of System Failures and Flammability
Observe the following precautions to prevent system problems.
Warning
The i• nstrument must be installed correctly according to the installation environment and the
installation conditions shown in this manual.
Please contact Beckman Coulter Technical Services, or the Sales Department when the system status•
is to be changed.
Preventing Electric Shock
To avoid an electric shock, observe the following precautions.
Warning
Never remove the covers secured by screws, such as the rear cover and side covers, unless being•
guided by an Beckman Coulter Representative.
If liquid spills or leaks occur inside the system, contact Beckman Coulter Technical Services.•
Careless operation with liquid present may result in an electric shock.
Preventing Personal Injury
To protect yourself from injury while using the system, observe the following precautions.
Warning
While the system is operating, do not touch the moving parts. These include the sample syringes and•
probes, reagent syringes and probes, mix bars, wash stations, and rack feed unit. Do not insert your
ngers or hand in an opening.
To replace the photometer lamp, follow the procedures in “Chapter F, Maintenance.” Do not touch•
the lamp before it is cool or you may be burned.
Observe the precautions on the analyzer labels and in this manual.•
For information about precautions regarding the personal computer and printer, refer to the operator's•
manual supplied with the computer and printer.
Return to Table of Contents

Automated Chemistry Analyzer
AU2700 User's Guide Chapter A - Precautions and Installation Environments
A-3
March, 2000
Eye Protection
To protect your eyes, observe the following precautions.
Warning
The photometer lamp is lit while the system is on. Do not look into the lamp or the laser beam from the
barcode reader. Direct light from the photometer lamp or from the laser beam of the barcode reader may
result in eye damage.
Accuracy and Precision of Analysis Data
To obtain accurate analysis results, observe the following precautions.
Caution
Do not open the upper cover and/or rear cover during analysis.•
Before using the system, perform quality control procedures to verify the system functions correctly.•
Observe the instructions in this manual to inspect the system, perform maintenance, and replace•
parts.
Follow reagent manufacturer or distributor instructions when handling reagents, control serum, and•
reference material.
Handle the samples according to the instructions.•
Do not open the reagent refrigerator cover, cuvette wheel, large STAT table cover, or ISE cover•
during analysis.
Treating Waste Liquids
The waste liquid and mixtures may require special treatment before being discarded. This
system is structured to discard concentrated waste liquids (mixtures) and washing waste liquids
(washing water and detergents) separately. Observe the following precautions.
Caution
For proper waste disposal methods, refer to state and federal guidelines. For proper handling of
substances with a biosafety level 2, refer to the Centers for Disease Control/National Institutes of Health
manual "Biosafety in Microbiological and Biomedical Laboratories," 1984. Also, the following NCCLS
document provides guidance on the safe handling and disposal of chemical, infectious, radioactive, and
physical waste generated in the clinical laboratory. Refer to NCCLS document GP5-A Vol. 13 No. 22
"Clinical Laboratory Waste Management; Approved Guideline."

A-4 Chapter A - Precautions and Installation Environments Automated Chemistry Analyzer
AU2700 User's Guide
March, 2000
Preventing Infection
If samples used with the system are mishandled, there is a risk of being infected. To protect
yourself from infection, observe the following precautions.
Warning
Do not touch the samples, mixtures, and waste liquids with bare hands. Be sure to wear gloves to
protect yourself from infection. Should any samples come into contact with your skin, thoroughly wash
the area that came into contact with the sample and consult a physician. Immediately wipe off any
contaminants from the system.
Handling Reagents
Some reagents used with the system are strong acids or alkalis. To protect yourself from injury,
observe the following precautions.
Warning
Some reagents are strong acids or alkalis. Exercise great care so that your hands and clothing do
not come into contact with the reagents. If your hands or clothing come into contact with reagents,
immediately wash them off with soap and water. If a reagent comes into contact with your eye(s),
immediately rinse with water for at least 15 minutes and consult a physician. Consult the MSDS sheet
for the particular reagent you have come into contact with for additional information.
Preventing Damage to Other Equipment and Facilities
Warning
Power outlet connections should be properly installed so as not to seriously affect other important
equipment (e.g., surgical equipment power supply) or facilities due to system failure.

Automated Chemistry Analyzer
AU2700 User's Guide
A-4a
November 1, 2009
Caution
Checking test at analysis
To check tests following analysis, observe the system management and laboratory standards.
Before analysis, verify the following:
Check the puried water quality•
Check the calibration analysis results•
Check the quality control data•
Check the analysis result•
Check the probes and tubing for leaks•
Check the samples for contaminants (dust, brin, etc.)•
Check each sample quantity and verify that bubbles are not present•
Check the reaction data•
If any error ag (*, ?, @, $, D, B, !) is generated in relation to the reaction OD, check the processed
reaction data immediately before and after the agged abnormal result. If any abnormality is present,
check the cuvette and the cuvette washing station for an overow, recheck any processed results
before and after the agged result.
Precautions for maintaining/inspecting the system and periodic replacement of parts.
Maintain and inspect the system, replacing parts periodically according to the instructions in this•
manual. If the system is not correctly maintained, analysis results will be effected.
After replacing main parts such as the photometer lamp, syringes, probes, and cuvettes, perform•
calibration. Follow the reagent manufacturer or distributor’s instructions for information about
timing, frequency, and materials required for calibration analysis.
Use only detergents that meet type, density, and usage specications specied in this manual. If the • detergent does not meet specications, or is used incorrectly, analysis will be effected.
Use of consumables
To avoid a decrease in system performance, use only consumables and parts recommended by Beckman
Coulter.
Precautions for setting analysis parameters
The sample quantity, reagent quantity, measurement wavelength, calibrator value, etc., must be set on the
analyzer before analysis can be performed. Use the values set in the package insert for the reagent etc.
Make sure to follow the manufacturers or distributors instructions for the reagent and all the instructions
outlined in this manual.
Other Cautions
If reagents or samples accidently come in contact with the mucous membranes or are accidently ingested,
rinse immediately or induce vomiting. Follow the manufacturers or distributors instructions also located
on the package insert, and contact a physician immediately.

A-4b Automated Chemistry Analyzer
AU2700 User's Guide
November 1, 2009
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Automated Chemistry Analyzer
AU2700 User's Guide
A-5
March, 2000
2. Precautions on Use
To use the system safely and effectively, observe the following precautions.
Special considerations when using the Windows NT operating system:
Do not play audio CDs or games on the Windows NT computer. This may compromise the•
performance of the system.
Do not press Control + Alt + Delete to access Windows NT programs. This compromises•
the integrity of the operating system.
Only play the maintenance video clips in the Standby mode. Playing videos in a measure•
mode could compromise analyzer performance.
To exit the menu and operation help programs, use "Exit Help" located in the bookmark•
column located to the left side of the screen. Do not click random areas of the screen to
close help programs. The application will continue to run in the background.
Do not press any keys on the keyboard when the analyzer is rst turned on (booting-up). •
You may use the keyboard when the password or start-up screen appears.
Do not change indexes during a measure mode. This will cause the analyzer to function•
inappropriately and could affect results.
Do not attempt to change parameters during a measure mode. This will compromise the•
integrity of your system and data.
Do not use a screen saver. This could cause the analyzer to function inappropriately.•
General Precautions During Use of the System
Caution
Handling samples (Samples available for analysis)
This system is designed to analyze serum, urine, and other body uids. If problems are •
encountered when analyzing a specic test or when using a specic reagent, consult the
reagent manufacturer or distributor.
Use serum that is sufciently separated from blood clots and urine that is free from •
suspended matter or the probe may be clogged and adverse affects on analysis may
result. The analyzer clot detection function is affected by the amount of sample aspirated.
Clot detection occurs inconsistently when the sample volume for a test is < 16uL.
Exercise care when mixing chemicals (medicine, anticoagulant, preservative, etc.).•
Handling samples (Storing samples)
Store samples according to your laboratory protocol. Improper storage of samples may•
compromise the integrity of the sample. Example: Refrigeration of blood increases
potassium in the blood.
Handling samples (Pretreating samples)
Fibrin suspended in the serum may clog the probe.•

A-6 Automated Chemistry Analyzer
AU2700 User's Guide
March, 2000
Check that the blood is sufciently coagulated prior to serum separation. Remove the •
suspended brin before placing serum on the system.
If any suspended matter is recognized in the urine to be dispensed, perform centrifugal•
separation to precipitate the suspended matter before testing the urine specimen.
If a sample requires pretreatment depending on the analysis test, consult the reagent•
manufacturer or distributor. For information about which serum separating medium is
appropriate for the sample, consult the reagent manufacturer.
A minimum quantity of sample is required for analysis. Set up an appropriate quantity of•
sample for correct sampling in the system, according to this manual.
To prevent sample evaporation, do not leave samples unsealed for an extended period of•
time. If samples evaporate, correct analysis cannot be obtained.
Handling reagents, reference materials, and control serums
To analyze serum, urine, or other samples using this system, the appropriate reagent,•
reference material, and control serum are required. For information about which products
to use, consult the reagent manufacturer, the distributor, or Beckman Coulter Technical
Services.
For reagent reference material, or control serum storage and handling, use the instructions•
of the reagent manufacturer or distributor.
The methods used to store the reagents, reference materials, and control serums are•
described in each package insert. Observe the instructions. If reagents, reference
materials, and control serums are stored improperly, results will be inaccurate even
if they are used within effective periods. Also, top system performance may not be
obtained.
Consult the corresponding reagent manufacturer or distributor for the stability of the•
unsealed product.
To place the reagent, etc., on the system, follow the instructions in this manual and•
those from the reagent manufacturer or distributor. Unless the reagent is placed properly,
accurate analysis results cannot be obtained and damage to the system could occur.
After replacing the reagent, follow the instructions on the package insert.•
Reagent interference between analysis tests
If a reagent is contaminated with another reagent during analysis, results may be affected.
The actual degree of interference differs depending on the reagent. For detailed information,
contact the reagent manufacturer or distributor. For information on how to check for cross-
contamination between tests, contact Beckman Coulter Technical Services.
Analysis performance
A high ratio of the following may affect the analysis result: hemolysis, turbidity, or
bilirubin, the drug used or its metabolite. For detailed information, contact the reagent
manufacturer or distributor. Also consult the reagent manufacturer or distributor for detailed
information about the analysis performance of each reagent.

Automated Chemistry Analyzer
AU2700 User's Guide
A-7
March, 2000
Water supply and drain hoses
According to the description given in the "Installation Environments” section, have the
connection of hoses for water supply and drainage made by authorized personnel. If
the hoses are connected to other facilities in other ways than specied, they may be
disconnected during operation of the system. This will cause a serious problem such as
water leakage in the system.
Electromagnetic waves of the CRT monitor and the data processing unit
Please do not place equipment generating electromagnetic waves, like computers,
monitors, etc., close to the system. The CRT monitor and the data processing unit generate
electromagnetic waves. Exposure to excessive amounts of electromagnetic waves may
interfere with instrument operation.
Maintaining guaranteed system performance
Use the system between 18 and 32 °C, 40 and 80% RH, and ±2 °C temperature uctuation
during analysis. If the system is operated outside of the above ranges, analyzer performance
cannot be guaranteed.
Handling the keyboard and monitor
To prevent the keyboard or monitor from deteriorating, do not touch the keyboard or
monitor with hands that are wet or have chemicals on them.
Operating the system
Upon completion of analysis, check the sample numbers and sample IDs.•
To operate this system, observe the procedures described in this manual. Incorrect•
operation may result in improper analysis results or system failure.
To learn about total system operations, take the training course offered by Beckman•
Coulter. This manual is intended for personnel who have completed the training course
offered by Beckman Coulter, or personnel who have been trained by someone who has
taken the course.
Checking tests at analysis
To insure quality results, periodically check the following:
Quality of puried water•
C• alibration results
QC data•
Analysis results•
Syringes and tubing for leaks•
S• amples for contaminants (dust, brin, etc.)
Quantity of each sample and that no bubbles are present•
Precautions for maintaining/inspecting the system and periodic replacement of parts
Maintain and inspect the system, and periodically replace the parts according to the•
instructions in this manual. If the system is not maintained correctly, reliable analysis
results might not be obtained
If replacing main parts such as the photometer lamp, syringe, probe, or cuvette(s), follow•
any special instructions in this manual. For information about timing, frequency, and
reference materials required for calibration, follow the package inserts from the reagent
manufacturer or distributor.