CESCO GlucCell Operator's manual

GlucCell
TM
Glucose Monitoring System
User Instruction Manual
Ver.1.1
Caution
Read the User’s Manual thoroughly before use.
This User’s Manual is designed to guide you through the
operation of the GlucCellTM Glucose Monitoring System with
detailed directions and illustrations. Read the entire the User’s
Manual before you begin test to ensure that you use this
system properly and receive accurate results.
GlucCellTM is a trade mark of CESCO Bioengineering Co., Ltd.

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Contents
Chapter 1 About the GlucCellTM System........................3
1.1 Intended Use.......................................................3
1.2 Characteristics ...................................................3
1.3 Limitations of the system ..................................3
1.4 Component List..................................................4
1.5 About the Glucose Meter...................................4
1.5.1 Front-side of the Meter ............................4
1.5.2 Backside of the Meter..............................4
1.5.3 LCD Display..............................................5
1.6 About the Glucose Test Strip ............................5
1.6.1 Glucose Test Strip....................................5
1.6.2 Test Strip Vial ...........................................5
1.7 About the Check Strip........................................6
1.8 About the Code Key ...........................................6
Chapter 2 Install/Replace Battery ..................................6
2.1 How to install/replace the battery .....................6
WARNING..................................................................7
Chapter 3 Set the Glucose Meter ...................................8
3.1 How to enter into Set Mode...............................8
3.2 Setting the Year ..................................................8
3.3 Setting the Month...............................................8
3.4 Setting the Day ...................................................9
3.5 Setting the Hour .................................................9
3.6 Setting the Minutes ............................................9
3.7 Setting the Unit of Measurement ......................9
Chapter 4 Code the Glucose Meter..............................10
4.1 Why to code the meter.....................................10
4.2 When to code the meter ..................................10
4.3 How to Code the Meter ....................................10
Chapter 5 Perform a Glucose Test...............................11
Chapter 6 Test Results ................................................13
6.1 What your results mean...................................13
6.2 Low Glucose Value ..........................................13
6.3 High Glucose Value..........................................13
Chapter 7 Memory Recall .............................................14
7.1 How to enter into Memory Mode.....................14

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7.2 Memory Recall..................................................14
Chapter 8 Quality Control Test.....................................15
8.1 Quality Control by using the Check Strip ......15
Chapter 9 Display Message and Solution ...................15
Chapter10 Taking Care of your Glucose Meter...........17
Chapter11 Specifications of the System .....................18
Chapter12 Customer Service .......................................18

Chapter 1. About the GlucCellTM System
1.1 Intended Use
The GlucCell TM Glucose Monitoring System is intended for use by
laboratory researchers or bioreactor professionals to obtain a
quantitative measurement of glucose in cell culture media.
1.2 Characteristics
The GlucCellTM Glucose Monitoring system is a merging of glucose
biosensor technology with microprocessor-based instrumentation.
The glucose test strip requires a sample volume of less than 3 uL and
has a testing time of less than 15 seconds. The glucose meter is a
compact hand-held device with a large and easy-to-read display. The
meter can store 180 test results with corresponding times and dates.
1.3 Limitations of the system
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!
!
!
!
!
!
!
!
For in vitro research use only. Not for diagnostic testing.
GlucCellTM Glucose Test Strips can be used only with GlucCellTM
Glucose Meters.
The meter must be coded only with the corresponding code on the
vial of glucose test strips being used - the codes must match.
Use glucose test strips before their expiration date.
Test only with cell culture medium or equivalent buffer solution.
High concentrations of vitamin C and/or uric acid may affect the
test result.
High altitudes may affect the test result.
Temperatures outside the range of 10℃to 40℃(50℉to 104℉)
may affect the test result.

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1.4 Component List
These items are included in your starter kit of GlucCellTM Glucose
Monitoring System:
1. User’s Manual 1
2. Quick Reference Card 1
3. Glucose Meter 1
4. Glucose Test Strip *
5. Check Strip 1
6. Code Key 1
7. 3V Li+ Battery (inside the meter) 1
8. Carrying Bag 1
* Quantity varies according to the order
8
6
5
4
3
1.5 About the Glucose Meter
1.5.1 Front-side of the Meter
1 LCD Display：
Shows test results and other information.
2 Mem/Set Button(M/S Button)：
# Turns the meter on/off (press and hold for
4 secs to turn off)
# Enters into Memory Mode
# Changes parameters in Set mode
3 Func. Button(Func. Button)：
# Turns the meter on
# Enters into Set Mode
# Confirms parameters in Set Mode
4 Strip Slot：
The slot is a connector for the glucose test strip,
Code Key, and Check Strip.
2
3
1
4
1.5.2 Backside of the Meter
1 Data Port：
Used with the optional GlucCell TM transferring cable
and GlucCellTM Manager software for data transfer
from the meter to a computer for analysis.
2 Battery Cover：
Slides down for battery access.
2
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1.5.3 LCD Display
1 Numerical Display: Data display
2 Battery symbol: Low battery indication.
3 Thermometer symbol:
Out-of-range temperature indication.
4 droplet symbol: Ready for test indication.
5 Strip symbol:
Ready for strip insertion indication.
6 M188: Memory number display.
7 mg/dL; mmol/L: Selected unit display.
8 DAYAVG:
Number of days average display.
9 Date: Month/day display.
10 Time: Time display.
1.6 About the Glucose Test Strip
1.6.1 Glucose Test Strip
1 Connector End
2 Sample Chamber (on the rear side of
test strip)
3 Reaction zone
Rear
Front
2
2
1
3
1.6.2 Test Strip Vial
1 Code Number
2 Expiration Date
3 Discard Date:
90 days from first opening of vial.
3
2
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1.7 About the Check Strip
The Check Strip is used to check the function of
the meter
1 Connector End
1.8 About the Code Key
1 Connector End
2 Code Number:
The code number on the Code Key must
match with code number on the test strip vial
being used.
Chapter 2 Install/Replace Battery
2.1 How to install/replace the battery
1 Push the battery cover with two thumbs and
slides down to open.
2 Replace with a 3.0 volt lithium battery (CR 2032)
into the battery compartment with the positive
(＋) side up.
3 Slide the Battery Cover up (until it snaps into
place) to close.
Notes

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Test results that are stored in memory will not be erased when you
replace the battery., if the new battery is installed needed within 30
minutes
WARNING
Discard the used battery according to your local environmental
regulations.

Chapter 3 Set the Glucose Meter
3.1 How to enter into Set Mode
1 Press any buttons to turn on the meter
2 Press the “Func. button” four times slowly and
successively by following the rhythm of
flashing symbols to enter into Set Mode. The
year filed flashes will show up first.
3.2 Setting the Year
1 The Year field flashes.
2 Press the “Mem/Set button” to change the
Year.
3 Press the “Func. button” to confirm the new
setting and to cycle on to the next setting (i.e.,
month).
3.3 Setting the Month
1 The Month field flashes.
2 Press the “Mem/Set button” to change the
Month.
3 Press the “Func. button” to confirm the new
setting and to cycle on to the next setting (i.e.,
Day).
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3.4 Setting the Day
1 The Day field flashes.
2 Press the “Mem/Set button” to change the Day.
3 Press the “Func. button” to confirm the new
setting and to cycle on to the next setting (i.e.,
Hour).
3.5 Setting the Hour
1 The Hour field flashes.
2 Press the “Mem/Set button” to change the
Hour.
3 Press the “Func. button” to confirm the new
setting and to cycle on to the next setting (i.e.,
Minutes).
3.6 Setting the Minutes
1 The Minutes field flashes.
2 Press the “Mem/Set button” to change the
Minutes.
3 Press the “Func. button” to confirm the new
setting and to cycle on to the next setting (i.e.,
Unit of Measurement).
3.7 Setting the Unit of Measurement
1 The Unit field flashes.
2 Press the “Mem/Set button” to change the Unit.
3 Press the “Func. button” to confirm the new
setting and to turn off the meter.
Notes
While in Set Mode, hold down the “Mem/Set button” to scroll through
the numbers quickly.
After the unit is set, the meter will turn off automatically.

Chapter 4 Code the Glucose Meter
4.1 Why to code the meter
A Code Key is provided in each box of GlucCellTM Glucose Test Strips.
It is used to code the glucose meter to match the corresponding code
on the test strip vial being used.
4.2 When to code the meter
The meter must be re-coded when a new box of glucose test strips is
being used for the first time.
4.3 How to Code the Meter
1 Insert the Code Key firmly into the strip slot.
2 Wait until a code number is displayed.
3 Check to make sure that the code number
displayed on the LCD matches the code number
on the test strip vial exactly.
4 Remove the Code Key.
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Note
Do not perform the test if the code number DISPLAYED on the LCD
does not match with the code number on the test strip vial being used.

Chapter 5 Perform a Glucose Test
1 Insert the glucose test strip fully into the strip
slot; the meter will turn on automatically.
RECAP THE STRIP VIAL IMMEDIATELY after
taking out the glucose test strip.
2 Check to make sure the code number matches
the code number on the strip vial being used.
3 The meter is ready for testing when the flashing
“
” Symbol appears.
Perform the test within three minutes;
otherwise, the meter makes a long beep and
turns off automatically.
4 Pipet around 10 μl of culture medium and
produce a small droplet in the tip of pipette.
5 Turn the meter side down and allow the sample
chambers on the strip side up. Touch the
culture medium drop to the sample chamber of
the test strip until the chamber is fully filled.
The meter will beep to indicate that the test has
started.
6 The Measuring Symbol is displayed to indicate
the test is in progress.
7 The test result is displayed and stored in
memory within 15 seconds. It remains displayed
for 3 minutes or until the glucose test strip is
pulled out.
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8 Record the test results in your log book.
9 Remove the test strip to turn off the meter. The
test result has been stored in memory.

Chapter 6 Test Results
6.1 What your results mean
# Test results are displayed in either mg/dL or mmol/L depending on
the unit setting (refer to Section 3.7 for how to set the meter). The mmol/L
results will always include a decimal point; mg/dL results do not
include a decimal point.
6.2 Low Glucose Value
The LO Symbol appears when your glucose test result is
less than 30 mg/dL (1.6 mmol/L).
6.3 High Glucose Value
The HI symbol appears when your glucose test result is
higher than 600 mg/dL (33.3 mmol/L). Note: In the
situation, please dilute the sample with PBS to proper
concentration for next test.
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Chapter 7 Memory Recall
The glucose meter stores the most recent 180 test results, from the
most recent “1” to the oldest “180”. Please set the time/date to ensure
that the corresponding times of testing have been recorded.
7.1 How to enter into Memory Mode
1 Press any buttons to turn on the glucose meter.
2 Press the “Mem/Set button” to enter into Memory
Mode.
7.2 Memory Recall
1 Press the “Mem/Set button” four times to recall
the recent test result, “M01”.
2 Repeat the previous step to retrieve all stored test
results.
Note
The meter will turn off after the last test result is recalled.
Press the “Func. Button” 4 times at any time to enter into Set Mode.
Hold the “Mem/Set button” for more than 3 seconds at any time to turn
off the meter.
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Chapter 8 Quality Control Test
8.1 Quality Control by using the Check Strip
1 Insert the Check Strip firmly into the strip slot
with the label face-up to start the Meter Quality
Control Test
2 “OK” will be displayed if your glucose meter is
functioning properly.
3 Remove the Check Strip to turn off the meter
Note
In the event that an error message is displayed (e.g., “E-E”), please
refer to chapter 10 for details.
Chapter9 Display Message and Solution
Display
Message:
“LO” reading
Cause Solution
Glucose
concentration
Your glucose test result is less than 30 mg/dL (1.6
mmol/L).
Meter malfunction Check to see if your meter is properly coded
Perform the Check Strip Test (refer to Section 8.1)
Test Strip
malfunction
Check expiration date.
Check to see if Sample Chamber is fully filled
Check Test Strip physical condition
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Display
Message:
“HI” reading
Cause Solution
Glucose
concentration
Your glucose test result is higher than 600 mg/dL (33.3
mmol/L).
Note: In the situation, please dilute the sample with PBS
to proper concentration for next test.
Meter malfunction Check to see if Meter is properly coded
Perform Check Strip Test (refer to Section 8.1)
Test Strip
malfunction
Check expiration date
Check Test Strip physical condition
Display
Message:
Cause Solution
Battery low Change the battery
Display
Message:
Cause Solution
Meter malfunction Perform Check Strip Test (refer to Section 8.1)
#
Ambient
temperature is
outside of the
acceptable range.
Perform the test in an environment within the
acceptable temperature range.
Temperature sensor
malfunction
#
Display
Message:
Cause Solution
Code Card failure Repeat coding procedure.
#

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Display
Message:
Cause Solution
Meter electronics
failure
Perform Check Strip Test (refer to Section 8.1)
#
Display
Message:
Cause Solution
The test strip may
be moist
Replace with a new glucose test strip.
The test strip may
have already been
used
Replace with a new glucose test strip.
Display
Message:
Cause Solution
The test strip is
defective
Replace a new glucose test strip
# - If the error message repeats, please contact your local dealer for
help.
Chapter 10 Taking Care of your Glucose Meter
The glucose meter does not need special care. When the meter is dirty, clean
it by wiping gently with a cotton swab or cloth. Do not use any liquids to clean the meter.
The following tips will help to keep the meter working properly:
Keep the meter, test strips and code card away from very high and
very low temperatures, and free from dust and dirt.
Keep the meter away from water or any other liquids.
Do not drop the meter.
Store the meter in the carrying bag and keep in good condition when
not in use.
Keep the meter away from UV.

Chapter 11 Specifications of the System
1. Assay Method Electrochemical biosensor
2. Test Sample Cell Culture Medium or equivalent solution
3. Test Result glucose (mg/dL or mmol/L)
4. Sample Size Less than 3.0µL (0.003 cc)
5. Measuring Range 30~600 mg/dL (1.6~33.3 mmol/L)
6. Measuring Time Less than 15 seconds
7. Memory Capacity Last 180 test results
8. Battery Type CR2032 3V-Lithium battery
9. Battery Life Approximately 1000 tests
10. Operating Temperature
Range
10℃~40℃(50℉~104℉)
11. Operating Relative
Humidity
20%~80%RH
12. Dimensions of the meter 96mm *60mm * 18.5mm
13. Weight of the meter 70 g included battery
14. Automatic Shut-off In 3 minutes
Chapter 12 Customer Service
If you have any questions about our products, please contact us:
CESCO Bioengineering Co., Ltd.
No. 36., 20th Rd., Taichung Industrial Park,
Taichung, Taiwan, R.O.C.
Tel: [phone]
Fax: [phone]
E-mail: info @cescobio.com.tw
Website: www.cescobio.com.tw
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