Lilly HUMALOG Mix50/50 KwikPen User manual

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Instructions for Use
HUMALOG®Mix50/50™KwikPen®
50% insulin lispro protamine suspension and
50% insulin lispro injection (rDNA origin)
100 units/mL, 3 mL pen
Read the Instructions for Use before you start taking HUMALOG Mix50/50 and each time you get
another KwikPen.There may be new information. This information does not take the place of
talking to your healthcare provider about your medical condition or your treatment.
Do not share your HUMALOG Mix50/50 KwikPen with other people, even if the needle has
been changed. You may give other people a serious infection or get a serious infection
from them.
HUMALOG®Mix50/50™KwikPen®(“Pen”) is a disposable prefilled pen containing 300 units of
HUMALOG Mix50/50.You can give yourself more than 1 dose from the Pen. Each turn (click) of
the Dose Knob dials 1 unit of insulin. You can give from 1 to 60 units in a single injection. If your
dose is more than 60 units, you will need to give yourself more than 1injection. The
Plunger only moves a little with each injection, and you may not notice that it moves. The Plunger
will only reach the end of the cartridge when you have used all 300 units in the Pen.
This Pen is not recommended for use by the blind or visually impaired without the help of
someone trained to use the Pen.
Pen Needle Parts
(Needles Not Included)
Paper Tab
Dose Knob
Outer Needle
Shield Inner Needle Shield Needle

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How to recognize your HUMALOG Mix50/50 KwikPen
•Pen color: Dark blue
•Dose Knob: Dark blue
•Labels: White label with red stripe
Supplies you will need to give your injection
•HUMALOG Mix50/50 KwikPen
•KwikPen compatible Needle (Becton, Dickinson and Company Pen Needles recommended)
• Alcohol swab
•Gauze
Preparing your Pen
•Wash your hands with soap and water.
• Check your Pen to make sure you are taking the right type of insulin. This is especially
important if you use more than 1 type of insulin.
•Do not use your Pen past the expiration date printed on the Label or for more than 10 days
after you first start using the Pen.
•Always use a new needle for each injection to help prevent infections and blocked
needles. Do not reuse or share your needles with other people. You may give other
people a serious infection or get a serious infection from them.
Step 1:
•Pull the Pen Cap straight off.
-Do not remove the Pen Label.
•Wipe the Rubber Seal with an alcohol swab.
-Do not attach the Needle before mixing.
Step 2:
•Gently roll the Pen between your hands 10
times.
Step 3:
•Move the Pen up and down (invert) 10
times.
Mixing by rolling and inverting the Pen is
important to make sure you get the right
dose.

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Step 4:
•Check the liquid in the Pen.
HUMALOG Mix50/50 should look white and
cloudy after mixing. Do not use if it looks
clear or has any lumps or particles in it.
Step 5:
•Select a new Needle.
• Pull off the Paper Tab from the Outer
Needle Shield.
Step 6:
•Push the capped Needle straight onto the
Pen and twist the Needle on until it is tight.
Step 7:
• Pull off the Outer Needle Shield.Do not
throw it away.
•Pull off the Inner Needle Shield and throw it
away.
Keep
Outer
Needle Shield
Throw Away
Inner
Needle Shield

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Priming your Pen
Prime before each injection.
•Priming your Pen means removing the air from the Needle and Cartridge that may collect
during normal use and ensures that the Pen is working correctly.
•If you do not prime before each injection, you may get too much or too little insulin.
Step 8:
•
To prime your Pen, turn the Dose Knob to
select 2 units.
Step 9:
•Hold your Pen with the Needle pointing up.
Tap the Cartridge Holder gently to collect air
bubbles at the top.
Step 10:
•Continue holding your Pen with Needle
pointing up.Push the Dose Knob in until it
stops,and “0” is seen in the Dose Window.
Hold the Dose Knob in and count to 5
slowly.
•You should see insulin at the tip of the
Needle.
-If you do not see insulin, repeat priming
steps 8to 10, no more than 4 times.
-If you still do not see insulin, change
the Needle and repeat priming steps 8
to 10.
Small air bubbles are normal and will not affect
your dose.
Selecting your dose
•You can give from 1 to 60 units in a single injection.
•If your dose is more than 60 units, you will need to give more than oneinjection.
-If you need help with dividing up your dose the right way, ask your healthcare provider.
- Use a new Needle for each injection and repeat the priming step.

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Step 11:
• Turn the Dose Knob to select the number of
units you need to inject. The Dose Indicator
should line up with your dose.
-The Pen dials 1 unit at a time.
-The Dose Knob clicks as you turn it.
-Do not dial your dose by counting the
clicks . You may dial the wrong dose.
This may lead to you getting too much
insulin or not enough insulin.
-The dose can be corrected by turning
the Dose Knob in either direction until
the correct dose lines up with the Dose
Indicator.
-The even numbers (for example, 12)
are printed on the dial.
-The odd numbers, (for example,25)
after the number 1, are shown as full
lines.
•Always check the number in the Dose
Window to make sure you have dialed
the correct dose.
(Example: 12 units shown
in the Dose Window)
(Example: 25 units shown
in the Dose Window)
•The Pen will not let you dial more than the number of units left in the Pen.
•If you need to inject more than the number of units left in the Pen, you may either:
-inject the amount left in your Pen and then use a new Pen to give the rest of your dose, or
-get a new Pen and inject the full dose.
•It is normal to see a small amount of insulin left in the Pen that you can not inject.