Thermo Scientific Thermo Scientific Dionex SRD-10 User manual

Dionex SRD-10 Suppressor Regenerant Detector
Installation Instructions
Document No. 065355
Revision 04
May 2018

© 2018 Thermo Fisher Scientific Inc. All rights reserved.
Chromeleon and SRS are registered trademarks of Thermo Fisher Scientific Inc. in the
United States.
All other trademarks are the property of Thermo Fisher Scientific and its subsidiaries.
Thermo Fisher Scientific Inc. provides this document to its customers with a product
purchase to use in the product operation. This document is copyright protected and any
reproduction of the whole or any part of this document is strictly prohibited, except with
the written authorization of Thermo Fisher Scientific Inc.
The contents of this document are subject to change without notice. All technical
information in this document is for reference purposes only. System configurations and
specifications in this document supersede all previous information received by the
purchaser.
Thermo Fisher Scientific Inc. makes no representations that this document is complete,
accurate, or error-free and assumes no responsibility and will not be liable for any errors,
omissions, damage, or loss that might result from any use of this document, even if the
information in the document is followed properly.
Revision history: Revision 01 released October 2010
Revision 02 released November 2010
Revision 03 released January 2012
Revision 04 released May 2018
For Research Use Only. Not for use in diagnostic procedures.

Doc. 065355-04 05/18 1
Dionex SRD-10 Installation Instructions
1. Overview
The Thermo Scientific™Dionex™SRD-10 Suppressor Regenerant Detector
(P/N 074395) is a stand-alone device that monitors liquid flow to a suppressor and
signals when to replenish the regenerant or external water supply. If the flow is
restricted or stops, the Dionex SRD-10 automatically disables the eluent pump.
The Dionex SRD-10 is intended for use with these applications:
•A Thermo Scientific™Dionex SRS®300 Self-Regenerating Suppressor that
is operated in the external water mode
•A Thermo Scientific™Dionex MMS™300 MicroMembrane™Suppressor
that is operated in the chemical regenerant mode
In the external water mode of operation, an external water supply is pumped into
the Dionex SRS regenerant channels. A constant current is applied across the
electrodes in the Dionex SRS to electrolytically regenerate the device. It is
possible for the IC (ion chromatography) system to continue to operate and for
current to be applied to the Dionex SRS even after external water flow has
stopped and the water supply is depleted. Unless the current is turned off, this will
quickly cause irreversible damage to the Dionex SRS.
In the chemical regenerant mode of operation, running out of regenerant will not
damage the MMS, but it will adversely affect the chromatographic run.

Dionex SRD-10 Installation Instructions
2Doc. 065355-04 05/18
TTL Control
In order to control the eluent pump, the Dionex SRD-10 must be connected to a
TTL input on one of the following Thermo Scientific products:
Power Requirements
The Dionex SRD-10 can be powered from any USB port in the IC system,
including one on the PC on which the Thermo Scientific™ Dionex Chromeleon® 7
or Chromeleon 6.8 Chromatography Data System software is installed. If a USB
port is not available, an external 5V USB power supply is required. The external
power supply is not provided with the Dionex SRD-10, but is readily available
elsewhere.
Dionex SRD-10 Ship Kit
The Dionex SRD-10 Ship Kit (P/N 074464) includes the following parts:
Integrated IC Systems Pump Modules
Dionex ICS-1100, ICS-1600, or ICS-
2100 Ion Chromatography System
Dionex ICS-3000 Dual Pump (DP), ICS-
3000 Single Pump (SP), ICS-5000 Dual
Pump (DP)*, or ICS-5000 Single Pump
(SP)*
Dionex ICS-1000, ICS-1500, or ICS-
2000 Ion Chromatography System
Dionex GP50 Gradient Pump, GS50
Gradient Pump, IP25 Isocratic Pump, or
IS25 Isocratic Pump (part of the Dionex
DX-600 and ICS-2500 product lines)
* Analytical pump only
Part Number Item Quantity
075422 Dionex ICS-3000 Dual Pump/ICS-3000
Single Pump Firmware CD
1
921019 Connector plug, 2-position* 1
* For connection to a pump module

Dionex SRD-10 Installation Instructions
Doc. 065355-04 05/18 3
2. Installation
Select the Dionex SRD-10 Installation Site
The Dionex SRD-10 must be installed within 50.8 cm (20 in) of the suppressor,
due to the length of the Dionex SRD-10 inlet tubing. It can be installed so as to
allow the regenerant or external water supply to exit the suppressor and flow
through the Dionex SRD-10 to waste.
Use the hook-and-loop strips on the rear of the Dionex SRD-10 to mount it on the
laboratory bench, the side of the IC system, or other flat surface. Any orientation
is acceptable.
Install the Dionex SRD-10
1. Turn off the power to the IC system (including the pump, detector,
autosampler, and chromatography compartment).
2. Connect the Dionex SRD-10 inlet tubing (labeled TO SRS/AES, REGEN OUT)
(see Figure 1, View A) to the REGEN OUT port on the suppressor.
Figure 1. Thermo Scientific Dionex SRD-10 Suppressor Regenerant Detector
View A View B
Hook-and-loop
strip (1 of 3)
Waste
Line
Inlet Tubing
TTL Output
USB Port

Dionex SRD-10 Installation Instructions
4Doc. 065355-04 05/18
3. Place the free end of the Dionex SRD-10 WASTE line (see Figure 1, View A)
in a waste container below the level of the workbench on which the IC system
is installed.
4. Remove the backing from the three hook-and-loop strips on the Dionex SRD-
10 (see Figure 1, View B).
5. While holding the Dionex SRD-10 in the preferred orientation, press it firmly
onto the mounting surface.
6. Refer to the table below to identify the TTL input that provides on/off control
of the pump motor.
7. Locate the appropriate connector plug in the Dionex SRD-10 Ship Kit. Follow
these basic steps to connect the TTL:
a. Connect the active wire (red) and ground wire (black) from the Dionex
SRD-10 to the connector plug.
To attach a wire to the plug, strip the end of the wire (if it is not already
stripped), insert it into the plug, and use a screwdriver to tighten the
locking screw. If necessary, multiple ground wires can be attached to a
single TTL input/output ground pin.
b. Plug the Dionex SRD-10 connector plug into the connector on the rear
panel of the integrated IC system or the pump module.
Product TTL Input
Dionex GP50, GS50, ICS-3000 SP, ICS-5000 SP*,
IP25, or IS25
TTL Input 1
Dionex ICS-1000, ICS-1500, or ICS-2000 TTL Input 3
Dionex ICS-3000 DP or ICS-5000 DP* Pump 1: TTL Input 2
Pump 2: TTL Input 3
Dionex ICS-1100, ICS-1600, or ICS-2100 Any available TTL input
* Analytical pump only
When attaching wires to the connector plug, be careful not to allow stray
strands of wire to short to the adjoining position on the connector.

Dionex SRD-10 Installation Instructions
Doc. 065355-04 05/18 5
c. Connect the wires from the Dionex SRD-10 connector plug to the TTL
connector pins on the other device.
NOTE Check the polarity of the connection. Connect the
signal wire to the signal (+) pin and the ground wire
to the ground (-) pin.
8. Plug the USB cable from the Dionex SRD-10 into any available USB port on
the IC system (or the optional external USB power supply).
9. Turn on the power to the IC system.
3. Chromeleon Setup
Before beginning operation of the Dionex SRD-10, you must verify that a pump
TTL input is configured in Chromeleon to control the eluent pump. In addition,
you may need to update the pump firmware. The following table indicates the
setup requirements for each pump.
The setup instructions vary slightly, depending on the chromatography software
used to control your IC system. If you are running Chromeleon 7, refer to
Section 3.1. If you are running Chromeleon 6.8, refer to Section 3.2.
Product Update pump firmware
to version 4.1.0 (or
later)?
Configure pump TTL
input to control eluent
pump?
Dionex ICS-1000, ICS-1100,
ICS-1500, ICS-1600, ICS-2000,
or ICS-2100
No Yes
Dionex ICS-3000 Dual Pump
(DP) or ICS-3000 Single Pump
(SP)
Yes Yes
Dionex ICS-5000 Dual Pump
(DP) or ICS-5000 Single Pump
(SP)
No Yes

Dionex SRD-10 Installation Instructions
6Doc. 065355-04 05/18
3.1 Chromeleon 7: Pump Setup
Start the Instrument Configuration Program
1. Stop all batches, programs, and data acquisition events on the
Chromeleon Controller that hosts the pump to be updated.
2. If it is not already running, start the Instrument Controller Service.
(Click Start > All Programs > Chromeleon 7 > Services Manager,
and then click Start Instrument Controller.)
The Chromeleon Services Manager status message should read
“Instrument Controller Service is running idle.”
3. Start the Instrument Configuration program. (Click Start > All
Programs > Chromeleon 7 > Instrument Configuration
Manager.)
4. If necessary, click the plus sign beside the controller name to display
the items underneath.
5. Expand the contents of the instrument that includes the pump to be
updated. (Click the plus sign next to the instrument.)
6. Right-click the pump to be updated and click Properties.
The Properties dialog box for the pump appears. In this example, the
pump is a Dionex ICS-3000 DP.

Dionex SRD-10 Installation Instructions
Doc. 065355-04 05/18 7
If the pump is a Dionex ICS-3000 DP or ICS-3000 SP, go to the next
section to update the firmware.
If the pump is not a Dionex ICS-3000 DP or ICS-3000 SP, go to page 8 to
configure the pump TTLs.
Download the New Dionex ICS-3000 DP/SP Firmware
1. On the General tab page in the Properties dialog box, click Install
Firmware. A message notifies you of the firmware version that is
currently installed in the pump and the version that will be
downloaded from the data system.
If firmware version 4.1.0 (or later) is already installed, click No to
cancel the download. Go directly to the next section to configure the
pump TTL inputs.
2. If the installed firmware version is earlier than version 4.1.0:
a. Click No to cancel the download.

Dionex SRD-10 Installation Instructions
8Doc. 065355-04 05/18
b. Insert the Dionex ICS-3000 Dual Pump/ICS-3000 Single Pump
Firmware CD into the appropriate drive.
c. Copy the pump firmware file from the CD to the \Bin directory of
your Chromeleon installation.
3. Click Install Firmware again. When the notification of the installed
firmware version appears, click Yes to update the firmware.
4. The download can take several seconds. When the download is
complete, remove the firmware CD from the drive. Store the CD in a
safe place, away from heat and moisture.
Configure the Pump TTLs
1. Click the Inputs tab in the pump Properties dialog box. Verify that
the correct TTL is selected.
For a Dionex ICS-3000 DP or ICS-5000 DP: If the Dionex SRD-10
is connected to Pump 1 and TTL 2, do not select the Pump_TTL_2
check box. If the Dionex SRD-10 is connected to Pump 2 and TTL 3,
do not select the Pump_TTL_3 check box.