vacuubrand BioChem-VacuuCenter BVC 01 User manual

Documents are only to be used and distributed completely and unchanged. It is strictly the users´ responsibility to check carefully
the validity of this document with respect to his product. Manual-no.: 999157 / 10/12/2009
page 1 of 31
BioChem-VacuuCenter
Instructions for use
Technology for Vacuum Systems
BVC 01
BVC 21 NT
BVC 21 NT VARIO

Documents are only to be used and distributed completely and unchanged. It is strictly the users´ responsibility to check carefully
the validity of this document with respect to his product. Manual-no.: 999157 / 10/12/2009
page 2 of 31
After sales service: Contact your local dealer or call [phone]
Dear customer,
Your VACUUBRAND diaphragm pumps should support you for a long time without trouble and with
maximal power. Thanks to our long practical experience we have much information how you could en-
sure powerful application and personal safety. Please read these instructions for use before the initial
operation of your pump.
VACUUBRAND diaphragm pumps are the result of many years of experience in construction and prac-
tical operation of these pumps combined with the latest developments in material and manufacturing
technology.
Our quality maxim is the ”zero fault principle”:
Every diaphragm pump, leaving our company, is tested intensively including an endurance run of 18
hours. Therefore also faults, which occur rarely, are identied and can be eliminated immediately.
The achievement of the specications after the endurance run is tested for every pump.
Every VACUUBRAND pump achieves the specications. We feel obliged to this high quality
standard.
We know that the vacuum pump can not take a part of your real work and hope that our products con-
tribute to an effective and trouble-free realisation of your work.
Yours
VACUUBRAND GMBH + CO KG
➨Danger! Immediate danger. Death or severe injuries as well as damage
to equipment and environment can occur.
☞Warning! Possible danger. Severe injuries as well as damage to equip-
ment and environment can occur.
• Caution! Possible danger. Slight injuries as well as damage to equip-
ment and environment can occur.
Note. Disregarding of notes may cause damage to the product.
Caution! Hot surface!
Isolate equipment from mains before removing the cover.
NOTICE

Documents are only to be used and distributed completely and unchanged. It is strictly the users´ responsibility to check carefully
the validity of this document with respect to his product. Manual-no.: 999157 / 10/12/2009
page 3 of 31
Contents
Safety information! .....................................................................................................4
General information............................................................................................................................4
Intended use.......................................................................................................................................4
Setting up and installing the system...................................................................................................4
Ambient conditions .............................................................................................................................5
Operating conditions ..........................................................................................................................5
Safety during operation ......................................................................................................................6
Maintenance and repair......................................................................................................................8
Technical data .............................................................................................................9
Wetted materials .............................................................................................................................10
System parts ................................................................................................................................... 11
Use and operation ...................................................................................................13
Installation ........................................................................................................................................13
During operation...............................................................................................................................13
Shutdown .........................................................................................................................................15
VacuuHandControl VHC..................................................................................................................16
Accessories - spare parts ........................................................................................18
Troubleshooting .......................................................................................................19
Replacing diaphragms and valves..........................................................................20
Removing cover hood from base plate............................................................................................21
Cleaning and inspecting the pump head.........................................................................................21
Replacing the diaphragm ................................................................................................................23
Assembling the pump head.............................................................................................................24
Assembling the connecting hoses...................................................................................................24
Mounting the cover hood.................................................................................................................25
Replacing the fuse...........................................................................................................................25
Assembling of components ....................................................................................26
Replacing the aspiration tube at the VHC .......................................................................................26
Replacing the lter...........................................................................................................................26
Assembling a second connection set VHC......................................................................................26
Cleaning and decontaminating ...............................................................................27
Notes on return to the factory .................................................................................28
Health and safety clearance form ...........................................................................29

Documents are only to be used and distributed completely and unchanged. It is strictly the users´ responsibility to check carefully
the validity of this document with respect to his product. Manual-no.: 999157 / 10/12/2009
page 4 of 31
General information
☞Before operating the equipment read and comply with the section ”Clean-
ing and decontamination”!
☞Read and comply with this manual before installing or operating the equip-
ment.
☞Lift and transport the equipment at the provided handles and/or recessed grips.
☞It is imperative to remove the transportation lock at the underside of the equip-
ment prior to use (BVC 21 NT / BVC 21 NT VARIO)! Keep the locking screws and
install again prior to further transportation!
Remove all packing material, remove the product from its packing-box, remove the
protective covers from the inlet and outlet ports and keep, inspect the equipment.
If the equipment is damaged, notify the supplier and the carrier in writing within three
days; state the item number of the product together with the order number and the
supplier’s invoice number. Retain all packing material for inspection.
Do not use the equipment if it is damaged.
If the equipment is not used immediately, replace the protective covers. Store the
equipment in suitable conditions.
Intended use
☞The system and all system parts are not to be used on humans or animals.
☞Prevent any part of the human body from coming in contact with the vacuum.
☞Make sure that the individual components are only connected, combined and op-
erated according to their design and as indicated in the instructions for use. Use
only original VACUUBRAND accessories.
☞Comply with notes on correct vacuum and electrical connections, see section
”Use and operation”.
• The systems are designed for ambient temperatures during operation between
+10°C and +40°C. Check the maximum temperatures if installing the system in
a cabinet or a housing and make sure ventilation is adequate. Install an external
automatic ventilation system if necessary.
Ensure that the equipment and all components are suitable for the intended applica-
tion. Use the system only for aspiration of liquids.
Setting up and installing the system
➨Equipment must be connected only to a suitable electrical supply and a suit-
able earth point. Failure to connect the motor to ground may result in deadly
electrical shock.
The supply cable may be tted with a moulded European IEC plug or a plug suit-
able for your local electrical supply. If the plug has been removed or has to be
removed, the cable will contain wires colour coded as follows: green or green and
yellow: earth; blue or white: neutral; brown or black: live. The devices BVC 01 and
BVC 21 NT have to be protected by an external fuse according to their current
draw (cf ”Technical data”). The BVC 21 NT VARIO has an internal fuse.
Safety information!
NOTICE
NOTICE

Documents are only to be used and distributed completely and unchanged. It is strictly the users´ responsibility to check carefully
the validity of this document with respect to his product. Manual-no.: 999157 / 10/12/2009
page 5 of 31
☞Do not permit any uncontrolled pressurizing (e.g. make sure that an exhaust
pipeline cannot become blocked). Risk of bursting!
☞Due to the high compression ratio of the pumps, pressure at the outlet port might
be generated being higher than the maximum permissible pressure compatible
with the mechanical stability of the system.
☞Always provide a free and pressureless exhaust pipeline.
• Comply with maximum permissible pressures and pressure differences, see
section ”Technical data”. Do not operate the pumping unit with overpressure at
the inlet or outlet.
• Check that mains voltage and current conform with the equipment (see rating
plate).
• Avoid overpressure of more than 0.2 bar in case inert gas is connected.
Provide a rm level platform for the equipment. Ensure a stable position of the pump
without any mechanical contact except of the pump feet. Comply with all applicable
safety regulations.
Install an external automatic ventilation system if necessary. Keep a distance of
minimum 20 cm between fan and ambient parts (e.g. housing, walls, ...). Check fan
regularly for dust/dirt, clean if necessary to avoid a cutback of ventilation. Avoid high
heat supply (e. g. due to hot process gases).
If the equipment is brought from cold environment into a room for operation, allow
the equipment to warm up (pay attention to water condensation on cold surfaces).
The diameter of the an outlet pipeline should be at the least as large as the diameter
of the pump connections.
Comply with all applicable and relevant safety requirements (regulations and
guidelines), implement the required actions and adopt suitable safety meas-
ures.
For aspiration of liquids connect the system BVC 01 to a suitable vacuum supply.
Ambient conditions
To the best of our knowledge the equipment is in compliance with the requirements
of the applicable EC-directives and harmonized standards (see ”Declaration of con-
formity”) with regard to design, type and model, especially directive IEC 1010. This
directive gives in detail conditions, under which the equipment can be operated safe-
ly (see also IP degree of protection).
Adopt suitable measures in case of differences, e. g. using the equipment outdoors,
installation in altitudes of more than 1000 m above mean sea level, conductive pol-
lution or bedewing.
Pay attention to the permissible maximum ambient temperatures (see ”Technical
data”).
Operating conditions
➨ The devices have no approval for operation in or for pumping of potentially
explosive atmospheres.
NOTICE
NOTICE

Documents are only to be used and distributed completely and unchanged. It is strictly the users´ responsibility to check carefully
the validity of this document with respect to his product. Manual-no.: 999157 / 10/12/2009
page 6 of 31
➨The devices are not suitable to pump
- unstable substances and substances which react explosively under
impact (mechanical stress) and/or when being exposed to elevated
temperatures without air,
-self inammable substances,
-substances which are inammable without air and
- explosive substance
• The devices are not suitable for pumping substances which may form deposits
inside the pump. Deposits and condensate in the pump may lead to increased
temperatures even to the point of excessing the maximum permitted tempera-
tures! Increased temperatures may cause ignition of inammable substances be-
ing eventually inside the pump.
• If there is a danger of the formation of deposits in the pump chamber (check inlet
and outlet of the pump), inspect the pump chamber regularly and clean if neces-
sary.
• The pumps are not suitable for pumping dust and have no approval for opera-
tion below ground.
If pumping different substances, it is recommended to purge the pump with air or
inert gas prior to changing the pumped media in order to pump out residues and to
avoid reactions of the pumped substances with each other and with the pump ma-
terials.
Take into consideration interactions and chemical reactions of the pumped
media. Ensure that the materials of the wetted parts are compatible with the pumped
substances, see section ”Technical data”.
Safety during operation
➨Adopt suitable measures to prevent the release of dangerous, toxic, explosive,
corrosive, noxious or polluting uids, vapours and gases. In case install an ap-
propriate collecting and disposal system and take protective action for pump and
environment.
➨If the equipment is used in combination with hazardous materials (e. g. in med-
ical-microbiological laboratories) check all relevant safety and health require-
ments and determine the applicability of regulatory limitations prior to use if nec-
essary.
➨Prevent any part of the human body from coming in contact with the vacuum.
➨Use appropriate safety work materials and methods if necessary, e. g. steam
sterilization, sterilization indicators or germicides. Notes concerning the steriliza-
tion of wetted parts (see ”Technical data”) see section ”Cleaning and decontami-
nating”. It is the user´s responsibility to ensure effective sterilization.
➨The user must take suitable precautions to prevent any formation of explosive
mixtures in the expansion chamber or in the housing. In case of e.g. a diaphragm
crack, mechanically generated sparks, hot surfaces or static electricity may ignite
these mixtures. Use inert gas for venting if necessary.
➨Potentially explosive mixtures at the outlet of the pump have to be drained ap-
propriately, sucked off or diluted with inert gas to non-explosive mixtures.
☞Pay attention to the symbol ”hot surfaces” on the equipment. Adopt suitable
measures to prevent any danger arising from hot surfaces. Allow pump to cool
down before starting maintenance.
NOTICE

Documents are only to be used and distributed completely and unchanged. It is strictly the users´ responsibility to check carefully
the validity of this document with respect to his product. Manual-no.: 999157 / 10/12/2009
page 7 of 31
• Use the system only in combination with the integrated hydrophobic lter (steriliz-
able) to protect pump and environment (people).
• Comply with applicable regulations when disposing of chemicals. Take into con-
sideration that chemicals may be polluted. Take adequate precautions to protect
people from the effects of dangerous substances (chemicals, thermal decompo-
sition products of uoroelastomers), wear appropriate safety-clothing and safety
glasses.
• Never operate a defective or damaged device.
• Check the collecting bottle regularly for ssures. Do never use a collecting bottle
with ssures nor expose it to vacuum.
• Use only OEM spare parts and accessories. Otherwise safety and perform-
ance of the equipment as well as the electromagnetic compatibility of the equip-
ment might be reduced.
Possibly the CE mark or the cTÜVus mark (see rating plate) become void if not
using OEM spare parts
Ensure that in case of failure the system always will turn into a safe status. Provide
appropriate protective measures (i.e precautions which allow for the requirements of
the respective application) even for the case of failure and malfunction. Operating
the pump, stand still of the pump or venting must not lead to a critical dangerous
situation under any circumstances.
Electronic equipment is never 100% fail-safe. This may lead to an indenite status
of the equipment. Failure of the pumping unit (e. g. by power failure) or connected
components, parts of the supply or change of parameters must not lead to a criti-
cal dangerous situation under any circumstances. In case of diaphragm cracks or
leaks in the manifold pumped substances might be released into the environment
or into the pump housing. Comply especially with notes on operation and use and
maintenance.
Maximum liquid level in collecting bottle: approx. 80 %, depending on the ap-
plication (in case of low boiling liquids or in case of suction of liquids which tend to
foam, the maximum liquid level might be reduced).
Due to the residual leak rate of the equipment, there may be an exchange of gas,
albeit extremely slight, between the environment and the vacuum system.
Adopt suitable measures to prevent contamination of the pumped substances or the
environment.
In case of overload the motor is shut down by a self-hold thermal cutout in the
winding.
Attention: Reset possible only manually. Switch off the pump or isolate the equip-
ment from mains. Identify and eliminate the cause of failure. Wait approx. ve min-
utes before restarting the pump.
Attention: In case of supply voltage below 100V, the lock of the cutout might be
restricted and the pump might restart on its own after sufcient cooling down. Take
suitable precautions, if an automatic restart of the pump may lead to a critical dan-
gerous situation.
The A-weighed emission sound pressure level of the pump does not exceed 70
dB(A). Measurement according to EN ISO 2151:2004 and EN ISO 3744:1995 with
standard silencer or exhaust tube at outlet.
NOTICE

Documents are only to be used and distributed completely and unchanged. It is strictly the users´ responsibility to check carefully
the validity of this document with respect to his product. Manual-no.: 999157 / 10/12/2009
page 8 of 31
Maintenance and repair
Wear parts have to be replaced regularly. In case of normal wear the lifetime of
the diaphragms and valves is > 10000 operating hours. Bearings have a typical du-
rability of 40000 h. Motor capacitors have a typical durability in the range of 10000
to 40000 h depending strongly on the operation conditions like ambient temperature,
humidity or load.
• Check every motor capacitor regularly by measuring its capacity and estimating
its operation time. Exchange old capacitors early enough to prevent a failure. If
an overaged motor capacitor fails it might get hot and even melt and may cause
a ame to form which could be dangerous for persons and equipment in the
vicinity. Motor capacitors have to be replaced by an electrician.
➨Before starting maintenance vent the system, switch off the device and isolate
the equipment from the electrical supply. Isolate equipment from mains before
removing the cover!
➨Before starting maintenance, isolate the equipment from mains and wait two min-
utes to allow the capacitors to discharge.
☞Ensure that the pump cannot be operated accidentally. Never operate the pump
if covers or other parts of the pump are disassembled. Never operate a defective
or damaged pump.
☞Attention: The pump might be contaminated with noxious or otherwise danger-
ous process chemicals that have been pumped during operation. Ensure that the
pump is decontaminated before maintenance and take adequate precautions to
protect people from the effects of dangerous substances if contamination has
occurred. Wear appropriate safety-clothing when you come in contact with con-
taminated components.
• Before starting maintenance vent the system and allow sufcient cooling of the
pump.
• Drain condensate, if applicable. Avoid the release of pollutants.
Ensure that maintenance is done only by suitably trained and supervised techni-
cians. Ensure that the maintenance technician is familiar with the safety procedures
which relate to the products processed by the pumping system.
In order to comply with law (occupational, health and safety regulations, safety at
work law and regulations for environmental protection) vacuum pumps, components
and measuring instruments returned to the manufacturer can be repaired only when
certain procedures (see section ”Notes on return to the factory”) are followed.
NOTICE

Documents are only to be used and distributed completely and unchanged. It is strictly the users´ responsibility to check carefully
the validity of this document with respect to his product. Manual-no.: 999157 / 10/12/2009
page 9 of 31
Technical data
We reserve the right for technical modications without prior notice!
Type BVC 21 NT VARIO BVC 21 NT BVC 01
Pump Pump Valve
Maximum pumping speed
(ISO 21360) m3/h 2.2 1.9/2.2* -
Ultimate vacuum (absolute) mbar 100 150 -
Maximum permissible inlet pres-
sure (absolute) bar 1.1
Maximum permissible outlet
pressure (absolute) bar 1.1
Rated power kW 0.09 0.12 0.03
No-load speed min-1 0-1800 1500/1800* -
Control range mbar 100 - atmosphere - -
Permissible ambient temperature
storage / operation °C -10 to +60 / +10 to +40
Permissible relative atmospheric
moisture during operation
(no condensation)
% 30 to 85
Maximum permissible range of
supply voltage
Attention: Observe specica-
tions of rating plate!
100-120 V~ +5%/-10% 50/60 Hz
230 V~ ±10% 50/60 Hz
Rated current at:
100-120 V~ 50/60 Hz
230 V~ 50/60 Hz
A
A
2 (maximum)
0.9 (maximum)
2.6 / 2.6
1.1 / 1.1
-
-
Internal fuse 4A SPT 5x20 - -
Motor protection thermal cutout, manual reset -
Degree of protection IEC 529 IP 20 IP 20 -
System System System
Volume of collecting bottle 4 4 4
Adapter for VHC pasteur pipettes, capillaries, pipette tips (100 µl)
Outlet hose nozzle DN 10 mm hose nozzle
DN 6/10 mm
Hydrophobic lter
Type
Manufacturer
Nominal pore diameter
Midisart®2000
Sartorius
0.2
Degree of protection IEC 529 IP 20 IP 20 IP 52
Dimensions L x W x H approx. mm 275 x 450 x 520 275 x 450 x
520
300 x 255 x
500
Weight approx. kg 14.5 12.2 4
* at 50/60 Hz

Documents are only to be used and distributed completely and unchanged. It is strictly the users´ responsibility to check carefully
the validity of this document with respect to his product. Manual-no.: 999157 / 10/12/2009
page 10 of 31
We reserve the right for technical modications without prior notice!
Wetted materials
Components Wetted materials
Pump
Head cover ETFE carbon bre reinforced
Housing cover insert PTFE carbon reinforced
Diaphragm clamping disc ETFE carbon bre reinforced
Diaphragm PTFE
Valve (BVC 21 NT) PTFE
Valve (BVC 21 NT VARIO) FFKM
Fittings ETFE / ECTFE
System
Pressure switch (BVC 01 / BVC 21 NT) PA, FPM
Sensor housing (BVC 21 NT VARIO) stainless steel
Sensor (BVC 12 NT VARIO) aluminium oxide ceramic
O-ring (Sensor BVC 21 NT VARIO) uoroelastomer
Seal ring PVC, FPM
Orice PET
Hose connections to pump head PTFE, PVC
Hose connection (outlet BVC 21 NT) ETFE / ECTFE
Hose nozzle (outlet BVC 01) PPS glass bre reinforced
Separator PP
Separator cover plate PP
Collecting bottle VTC
Bottle PP
Screw cap PP
Hose nozzle at screw cap PPS
Tube inside the bottle PE
Tube between bottle and pump PVC
Blind cap PPS glass bre reinforced
Coupling PP, stainless steel, EPDM
Filter
Diaphragm PTFE
Housing PP
Aspiration controller VHC
Hose silicone caoutchouc
Adapter PVC or PP

Documents are only to be used and distributed completely and unchanged. It is strictly the users´ responsibility to check carefully
the validity of this document with respect to his product. Manual-no.: 999157 / 10/12/2009
page 11 of 31
BioChem-VacuuCenter
BVC 21 NT / BVC 21 NT VARIO
(g.: BVC 21 NT VARIO)
separator
outlet
collecting bottle
screw cap
lter
coupling
connecting tube
On/off switch
VHC
adjusting knob for
vacuum control
(only BVC 21 NT VARIO)
recessed grip
Rear view:
handle
mains connection
rating plate
inlet diaphragm pump with coupling
(double sided sealed if removed)
blind cap
(for further connections)
➨Connect the tube of the VacuuHandControl VHC to the hose nozzle of the coupling of the bottle
head.
➨ Assemble the connecting tube with lter.
System parts

Documents are only to be used and distributed completely and unchanged. It is strictly the users´ responsibility to check carefully
the validity of this document with respect to his product. Manual-no.: 999157 / 10/12/2009
page 12 of 31
BioChem-VacuuCenter BVC 01
VacuuHandControl VHC
hose nozzle
(connection to vacuum supply)
xing clip
adapter
aspiration tube
control button
handle
thumb wheel
locking ring
pressure control device
blind cap
(for further connections)
lter
connecting tube
solenoid operated
isolation valve
inlet isolation valve with
coupling (double-sidedly
sealed if removed)
➨ Assemble the screw cap with lter and connecting tube.
➨Connect the tube of the VacuuHandControl to the hose nozzle of the coupling at the bottle head.
collecting bottle
screw cap
coupling
(connection VHC)

Documents are only to be used and distributed completely and unchanged. It is strictly the users´ responsibility to check carefully
the validity of this document with respect to his product. Manual-no.: 999157 / 10/12/2009
page 13 of 31
Use and operation
Installation
• It is imperative to remove the transportation lock prior to use! Tilt device care-
fully onto the side. Remove the four locking screws (wing screws) next to the fan
guard at the base plate. Put device back to normal operating position and keep
the locking screws.
• Make sure ventilation is adequate if equipment is installed in a housing or if ambi-
ent temperature is elevated. Keep a distance of minimum 20 cm between fans or
ventilation slots and ambient parts.
• Before switching on the equipment check that mains voltage and current
conform with the equipment!
Remove the protective foils from the ttings at the ask head and in case the protec-
tive covers from the inlet of the diaphragm pump, the solenoid operated valve (BVC
01) or the collecting bottle.
Assemble the connecting tube with lter between the bottle head and the inlet of
the diaphragm pump (BVC 21 NT / BVC 21 NT VARIO) or the inlet of the solenoid
operated valve (BVC 01).
Connect the aspiration tube of the VacuuHandControl VHC to the coupling at the
bottle head.
Connect the mains cable at the rear of the device (BVC 21 NT / BVC 21 NT VARIO)
or plug the mains cable into the pressure control device (BVC 01). Plug the IEC
socket of the solenoid operated valve (BVC 01) into the pressure control device.
If the pump is installed in altitudes of more than 1000 m above mean sea level check
compatibility with applicable safety requirements (motor may overheat due to insuf-
cient cooling).
The device BVC 21 NT VARIO features an internal fuse under the cover hood. See
section ”Replacing diaphragms and valves” when removing the cover hood to check/
replace the fuse.
During operation
• Maximum ambient temperature: 40 °C
• Operate the system only with the integrated hydrophobic lter.
Protection of the pump against liquids and contamination.
Protection of the environment/user against contamination (risk of infection!).
The VHC allows the aspiration of excess liquids. See section ”VacuuHandControl
VHC” for operation method.
The pump achieves its pumping speed, ultimate vacuum and vapour pumping
rate only at operating temperature (after approx. 15 minutes).
Prevent internal condensation, transfer of liquids or dust. The diaphragm and valves
will be damaged, if liquids are transferred through the pump in signicant amounts.
In case of excess temperature the motor is shut down by a thermal cutout in the
winding. Manual reset is necessary. Switch off the pump or isolate the equipment
from mains. Identify cause of failure and eliminate. Wait approx. ve minutes before
restarting the pump.
NOTICE
NOTICE

Documents are only to be used and distributed completely and unchanged. It is strictly the users´ responsibility to check carefully
the validity of this document with respect to his product. Manual-no.: 999157 / 10/12/2009
page 14 of 31
☞Check liquid level regularly. If neces-
sary drain separator.
➨Loosen union nut.
➨Remove separator. Drain condensate.
➨Assemble separator again, Tighten un-
ion nut hand-tight.
BVC 01:
When connecting a vacuum pump at the pressure control device: Maximum permit-
ted power draw at the connection of the vacuum pump: 6A ohmic, 1.5A inductive.
Draining the separator:
separator
union nut
Attention: In case of supply voltage below 100V, the lock of the cutout might be
restricted and the pump might restart on its own after sufcient cooling down. Take
suitable precautions, if an automatic restart of the pump may lead to a critical dan-
gerous situation.
After a power cut the system will automatically start again.
BVC 21 NT:
The vacuum pump operates at constant speed and is switched by an automatic
pressure control as necessary. Thus the collecting bottle provides the necessary
vacuum for the next aspirations. Avoid too frequent switching (> 5 switch points per
minute) of the vacuum pump (e.g. due to air intake).
BVC 21 NT VARIO:
The vacuum inside the collecting bottle can be controlled with the adjusting knob
(VACUUM) at the front of the device.
When turning the knob to the left (”+”, more vacuum), the diaphragm pump provides
a lower pressure inside the collecting bottle. The suction power is increased. If the
adjusting knob is turned to the right (”-”, less vacuum), the pump provides less
vacuum inside the bottle.
The speed of the pump is adapted via an internal control to the respective vacuum
demand. There is no abrupt switching of the pump. If the demanded vacuum level
inside the bottle is reached, the pump reduces its speed down to standstill.
Attention: If the adjusting knob is turned completely to the left or close to the stop
at the left (in direction ”+”, more vacuum), the vacuum demand might be below the
ultimate vacuum of the diaphragm pump. Thus the pump will run continuously at
highest speed. To avoid this mode of operation, reduce the vacuum demand slightly.
The vacuum pump will then reduce its speed automatically down to standstill once
the ultimate vacuum is reached.
The aspiration system doesn’t feature an air admittance valve. I.e. if the collect-
ing bottle is under vacuum and the vacuum demand is reduced (turning the adjust-
ing knob to the right), the existing underpressure inside the bottle remains until the
vacuum is reduced by further aspiration with the VHC (pressure rise in the collecting
bottle).
Avoid frequent switching on and off. After switching off wait 2 minutes before switch-
ing on again.
NOTICE

Documents are only to be used and distributed completely and unchanged. It is strictly the users´ responsibility to check carefully
the validity of this document with respect to his product. Manual-no.: 999157 / 10/12/2009
page 15 of 31
Shutdown
Short-term:
Has the pump been exposed to condensate?
Allow the pump to continue to run at atmospheric pressure for a few minutes.
Has the pump been exposed to media which may damage the pump materials or
form deposits? Check and clean pump head if necessary.
Long-term:
Take measures as described in section short-term shutdown.
Close inlet and outlet port (e. g. with transport caps).
Store the pump in dry conditions.
Shipment: Install transportation lock again.
NOTICE

Documents are only to be used and distributed completely and unchanged. It is strictly the users´ responsibility to check carefully
the validity of this document with respect to his product. Manual-no.: 999157 / 10/12/2009
page 16 of 31
VacuuHandControl VHC
The instrument allows the aspiration of excess liquids. The VHC is supplied completely with three differ-
ent adapters (included in delivery) to hold with pasteur pipettes, capillaries and pipette tips (100 µl).
Push the locking ring on the control button (release aspiration
tube).
Switch off pump.
Aspiration of liquid:
Press control button until the liquid has been aspirated. Re-
lease the control button to stop aspiration.
For controlled aspiration of excess liquids, the aspiration
speed can be regulated by using the integrated control but-
ton. Small amounts of liquids can be taken up manually by
using the thumb wheel and then sucked into the collecting
bottle.
Before aspiration:
Push back the locking ring from the control button.
Choose the appropriate adapter and carefully insert the pi-
pette into the adapter.
Position pipette tip by turning the xing clip in such a way that
working is comfortable and fatigue-proof. Remove adapter
from xing clip if is hard to turn. Squeeze xing clip and turn
to desired position. Put adapter back in xing clip.
Attention: Never insert lled pipettes due to risk of contami-
nation and infection. Wear protective gloves!
Working at different work places:
Disconnect bottle VTC with VacuuHandControl VHC from the
inlet of the pump. The bottle VTC is portable. If the aspira-
tion effect ceases, connect VTC to the diaphragm pump for
a short time until the pump is switched off by the automatic
pressure control (BVC 21 NT) or until the pump reduces its
speed down to standstill (BVC 21 NT VARIO).
After aspiration:
Carefully pull pipette out of the adapter.
Attention: Risk of contamination and infection. Wear protec-
tive gloves and eye protection! Dispose of pipettes according
to appropriate regulations.

Documents are only to be used and distributed completely and unchanged. It is strictly the users´ responsibility to check carefully
the validity of this document with respect to his product. Manual-no.: 999157 / 10/12/2009
page 17 of 31
Check liquid level in the collecting bottle regularly.
Maximally admissible liquid level in collecting bottle: ap-
prox. 80 %, depending on the application (in case of low boil-
ing liquids or in case of suction of liquids which tend to foam,
the admissible liquid level might be reduced).
Emptying of the collecting bottle:
☞Switch off pump or isolate pump from system, vent the
system (release VHC). Remove the connecting tube from
the lter, isolate connections in case.
☞Remove screw cap from the collecting bottle. Remove bot-
tle from the support. Sterilize and dispose of collected liq-
uid according to appropriate regulations.
Attention: Do not remove connections in case of liquid in
the tube. Do not touch contaminated parts when removing
the screw cap. Risk of infection! Wear appropriate protective
clothing, e.g. gloves.
The hydrophobic lter retains water and aqueous solutions
also in the form of aerosols. When using solvents or due to
evaporation of water, condensate may be recovered in the
separator.
☞Remove separator and drain condensate in case.
Important: Comply with applicable regulations when dispos-
ing of solvents.
Change lter if necessary (contaminated, no or bad aspira-
tion, pressure control device switches without demand of
vacuum).
☞Use only the original spare part and sterilize and dispose
of the lter according to appropriate regulations.
Note: After disinfection with alcohol allow the lter to dry com-
pletely because the lter may become clogged by alcohol.
Do not remove the metal tting at the screw cap.
If the tting is loose, tighten the tting carefully from the in-
side.
screw cap
lter element
metal tting
separator

Documents are only to be used and distributed completely and unchanged. It is strictly the users´ responsibility to check carefully
the validity of this document with respect to his product. Manual-no.: 999157 / 10/12/2009
page 18 of 31
Accessories - spare parts
Filter (hydrophobic) .................................................638266
Silicone tube (1 m) NW 9/6 ......................................638263
(connecting tube)
PVC tube (1 m) NW 12,8/6,4 .....................................638217
Collecting bottle VacuuTransContainer VTC .........688057
(with lter, coupling and blind cap)
Bottle with screw cap .............................................638246
(Without lter, coupling, blind cap; screw cap unmachined)
VacuuHandControl VHC ..........................................688056
Connection set VHC .................................................688060
(to connect a VHC to the VTC)
Silicone tube (sold by metre) NW 6/3 .......................636156
(aspiration hose for VHC)
Angular connector for rapid coupling ...................638252
(inclusive O-ring)
Various adapters (e.g. 8-channel manifold) as well as micro
pipettes or Pasteur pipettes are available at BRAND GMBH +
CO KG (www.brand.de/en).

Documents are only to be used and distributed completely and unchanged. It is strictly the users´ responsibility to check carefully
the validity of this document with respect to his product. Manual-no.: 999157 / 10/12/2009
page 19 of 31
Troubleshooting
Fault Possible cause Remedy
❑ Pump fails to start, sys-
tem becomes vented.
➨Mains not plugged in, failure
of electrical supply?
✔Plug in mains plug. check
mains fuse.
➨Motor overloaded? ✔Allow motor to cool, identify
cause of failure.
➨Pressure control device de-
fective?
✔Contact your local distributor.
➨Internal fuse blown (BVC 21
NT VARIO)?
✔Identify cause of failure, re-
place fuse (under the cover).
➨Adjusting knob at right stop
position (atmosphere, no
vacuum)?
✔Turn adjusting knob in direc-
tion “+“ (more vacuum).
➨Filter clogged? ✔Replace lter.
❑No aspiration at the VHC,
pipette drips.
➨Adapter or aspiration tube
defective?
✔Replace adapter with aspira-
tion tube.
➨Filter clogged? ✔Replace lter.
➨Leak at the bottle head? ✔Check seals, coupling and
blind cap. Screw in or re-
place if necessary.
➨No pumping speed of the
pump?
✔Perform maintenance, re-
place diaphragm and valves
if necessary.
➨Adjusting knob at right stop
position (atmosphere, no
vacuum)?
✔Turn adjusting knob in direc-
tion “+“ (more vacuum).
❑Pressure control device
switches frequently.
➨Leak in the system? ✔Check tubing, seals, coupling,
and blind cap. Screw in or
replace if necessary.
➨Filter clogged? ✔Replace lter.
➨Diaphragms or valves of the
pump defective?
✔Perform maintenance, re-
place diaphragm and valves
if necessary.
❑Pump is running continu-
ously.
➨Leak in the system? ✔Check tubing, seals, coupling,
and blind cap. Screw in or
replace if necessary.
➨Pressure control device de-
fective?
✔Contact your local distributor.
➨Adjusting knob at left stop
position or close to it (vacuum
demand below ultimate
vacuum of the pump)?
✔Turn the adjusting knob to
the right in direction “-“ (less
vacuum).
A service manual with exploded view drawings, spare part lists and directions for
repair is available on request (only in German or English).
☞The service manual is for trained service people.
NOTICE

Documents are only to be used and distributed completely and unchanged. It is strictly the users´ responsibility to check carefully
the validity of this document with respect to his product. Manual-no.: 999157 / 10/12/2009
page 20 of 31
Tools:
- Phillips screw driver size 2
- Hex key size 2.5 / 5
- Screw driver Torx TX20
- Flat bladed screw driver
- Face wrench with torque indicator
- Flat pliers
☞ Please read section ”Replacing diaphragms and valves” completely before
starting maintenance.
Partially the pictures show pumps in other versions. This doesn’t inuence replacing diaphragms and
valves of the pump.
Set of seals BVC 21 NT ...........................................................................................................696813
Diaphragm BVC 21 NT VARIO ....................................................................................................639786
Valve BVC 21 NT VARIO......................................................................................................... 2x 637225
Face wrench with torque indicator ..............................................................................................637580
Replacing diaphragms and valves
All bearings are encapsulated and are lled with long-life lubricant. Under normal ope-
rating conditions, the pump is maintenance free. The valves and diaphragms as well as
the motor capacitors are wear parts. If the rated ultimate vacuum is no longer achieved
or in case of increased noise level, the pump interior, the diaphragms and the valves
must be cleaned and the diaphragms and valves must be checked for cracks or other
damage. Check motor capacitors regularly by measuring their capacity and estimating
their operation time. Exchange old capacitors early enough to prevent a failure. The
capacitors have to be replaced by an electrician.
Depending on individual cases it may be efcient to check and clean the pump heads
on a regular basis. In case of normal wear the lifetime of the diaphragms and valves is
> 10000 operating hours.
☞Prevent internal condensation, transfer of liquids or dust. The diaphragm and
valves will be damaged, if liquids are pumped through the pump in signicant
amount.
If the pump is exposed to corrosive gases or vapour or in case of deposits, mainte-
nance should be carried out frequently.
☞Regular maintenance will improve the lifetime of the pump and also protect both
personnel and environment.
Ensure that maintenance is done only by suitable trained and supervised tech-
nicians. Ensure that the maintenance technician is familiar with the safety proce-
dures which relate to the products processed by the pumping system.
☞ Before starting maintenance vent the system. Uncouple the collecting bottle
and remove. Isolate equipment from mains before removing the cover!
Wait two minutes to allow the capacitors to discharge. Allow sufcient cool-
ing of the pump. Drain condensate, if applicable. Avoid the release of pollutants.
☞Ensure that the pump cannot be operated accidentally. Never operate the pump
if covers or other parts of the pump are disassembled. Never operate a de-
fective or damaged pump.
•Attention: The pump might be contaminated with noxious or otherwise danger-
ous process chemicals that have been pumped during operation. Ensure that the
pump is decontaminated before maintenance and take adequate precautions to
protect people from the effects of dangerous substances if contamination has oc-
curred.
• Wear appropriate safety-clothing when you come in contact with contaminated
components. Avoid the release of pollutants.
NOTICE