Agilent Technologies 400/54 Premium Shielded NMR Magnet System Installation guide

Agilent Technologies
Agilent 
400/54 Premium
Shielded NMR Magnet
System
System Overview

Notices
© Agilent Technologies, Inc. 2012
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Manual Part Number
9100380100
Edition
Revision A, April 2012
Printed in USA
Agilent Technologies, Inc.
5301 Stevens Creek Boulevard 
Santa Clara, CA 95051 USA
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Safety Notices
CAUTION
A CAUTION notice denotes a haz-
ard. It calls attention to an operat-
ing procedure, practice, or the like
that, if not correctly performed or
adhered to, could result in damage
to the product or loss of important
data. Do not proceed beyond a
CAUTION notice until the indicated
conditions are fully understood and
met.
WARNING
A WARNING notice denotes a
hazard. It calls attention to an
operating procedure, practice, or
the like that, if not correctly per-
formed or adhered to, could result
in personal injury or death. Do not
proceed beyond a WARNING
notice until the indicated condi-
tions are fully understood and met.

400/54 Premium Shielded NMR Magnet System Product Overview 1
Contents
1 Introduction
Safety Warnings 6
Compliance Notice 8
Contact Information 9
Europe 9
USA 9
Agilent website (all countries) 9
Important Notice 10
Disclaimer 10
2 Installation and Operation Safety
Introduction 12
Nature of the Magnetic Field 13
Hazards Presented by the Magnetic Field 14
Magnetic Field Safety Requirements 15
Exclusion Zone (5-gauss line) 15
Magnetic Attraction Zone 16
Occupational exposure to magnetic fields 16
Nature of Liquid Cryogens 17
Hazards Presented by Cryogens 18
Siting Requirements 20
Vents or quench ducts 20
Adequate ventilation during magnet installation 21
Oxygen monitor 21
Routine maintenance involving transfer of cryogens 22
Advice 22
Electrical Safety 23
Safe Access When Working at Height 24
Considerations for the Outbreak of Fire 25
General Safety — Potential Hazards 27
Handling cryogens (liquid helium and liquid nitrogen) 27
Vacuum hazards 27
Magnetic field 28
Air quality 28
System mechanical stability 29

2 400/54 Premium Shielded NMR Magnet System Product Overview
3 Maintenance
Commissioning and Decommissioning the Magnet 32
General safety note 32
Cryostat Maintenance 35
General maintenance 35
Cryogenic Fills 38
Safety during cryogen fills 38
How to perform a routine LN2 fill 38
How to perform a standard helium fill (top-up) 40
Parts List and Order Form 50
Parts Quotation Request 51
Information Sheet 53
4 Reference
Nitrogen Probe Calibration Chart — 400/54 Premium Shielded 56
Helium Probe Calibration Chart — 400/54 Premium Shielded 57
Temperature Sensors — 400/54/ASP 59
Platinum resistor thermometers (PT100) 59
Allen-Bradley temperature sensors 59
Location of temperature sensors 59
Wiring Diagram 60
10-pin seal pin designations, 400/54/ASP 60
19-way shim socket pin designations – 400/54/ASP 62
5 Agilent E5025 Cryogen Monitor
Safety 66
Compliance Notice 67
Overview 68
Description and Operating Principle 70
Technical specification 72
The Top-Level USER Menu 73
Manually reading the helium probes 73
Changing to the Helium Fill mode 73
Checking both Helium probe readings 74
The Secondary Level SET-UP Menu 75
Entering the secondary level SET-UP menu 75
Functions available on the secondary level SET-UP menu 75
Cryogen Monitor User Interface 79

400/54 Premium Shielded NMR Magnet System Product Overview 3
Modes of operation 79
Application start-up 80
Reader-mode user interface 80
N2and He Level history plot windows 82
Writer-mode user interface 83
Errors and Alarms 85
Ethernet Communication 86
Ethernet 86
6 Technical Specifications
System Description 88
The Superconducting Magnet 89
General description 89
Magnet specifications 90
Superconducting shim coils 90
The Cryostat 92
General Description 92
Specifications 92
Customer Interface Drawings 94
System Components 96
Superconducting magnet system components 96
Standard ancillary parts provided with the system 96

4 400/54 Premium Shielded NMR Magnet System Product Overview

5
Agilent 400/54 Premium Shielded NMR Magnet System
System Overview
Agilent Technologies
1
Introduction
Safety Warnings 6
Compliance Notice 8
Contact Information 9
Important Notice 10

6 400/54 Premium Shielded NMR Magnet System Product Overview
1Introduction
Safety Warnings
WARNING
This device produces a high magnetic field. The stray field
surrounding the magnet extends far beyond the confines of the
vessel. The existence of this field produces several hazards. In
particular, make sure people with cardiac pacemakers avoid the
region of field. The FDA guideline for cardiac pacemakers is
currently 5 gauss. Fields higher than this can cause malfunction of
the pacemaker. The field will interfere with sensitive electronic
devices and will erase magnetic storage devices such as tapes
and credit cards.
WARNING
Ferromagnetic objects in the vicinity of the magnet will become
magnetized and will be attracted toward the magnet. The force on
such objects is proportional to their mass so that even large
objects will move toward the magnet with considerable velocity.
WARNING
Under fault conditions, it is possible for large amounts of helium
and/or nitrogen to be released from the system (for example,
during a magnet quench). Under these conditions, the gas is very
cold and can cause “cold burns”. If the gas is not vented properly,
asphyxiation is possible due to the displacement of oxygen within
the room. It is the responsibility of the user to ensure adequate
venting of the gas is provided and adequate ventilation within the
final installation site.
NOTE
It is the responsibility of the user to take all necessary precautions to
prevent accident or loss from use of the magnet. Agilent Technologies
accepts no responsibility for any loss or damage caused either directly or
indirectly from use of the magnet. Every effort is made that the information
contained in this manual is correct. However, Agilent Technologies
accepts no responsibility for any inaccurate statements or omissions.

Introduction 1
400/54 Premium Shielded NMR Magnet System Product Overview 7
WARNING
Limit the magnet power supply to the operating current of the
magnet plus 10%. Energize the magnet only after completion of
cooling.
NOTE
Agilent Technologies makes available technical information and parts for
repair or maintenance where appropriate.

8 400/54 Premium Shielded NMR Magnet System Product Overview
1Introduction
Compliance Notice
Marking by the symbol indicates compliance of this
device to the PED (Pressure Equipment Directive) directive
of the European Community. This unit is to be installed and
operated as detailed. Any modification or maintenance
procedure undertaken which is not approved by Agilent
Technologies UK Ltd could nullify the marking of this
product and lead to prosecution. A 'Declaration Of
Conformity' in accordance with the above directive has been
made and is located at Agilent Technologies, Yarnton,
Oxfordshire, UK.

Introduction 1
400/54 Premium Shielded NMR Magnet System Product Overview 9
Contact Information
Europe
Address:
Agilent Technologies UK Ltd.
6 Mead Road
Oxford Industrial Estate
Yarnton, Oxfordshire OX5 1QU
Telephone Numbers:
To find contact information for your country, click the
following link, select your country, and then click Go.
http://www.chem.agilent.com/en- us/ContactUS/Pages/Contact
Us.aspx
USA
Address:
Agilent Technologies, Inc.
5301 Stevens Creek Blvd.
Santa Clara, CA 95051
Telephone Numbers:
Toll Free: [phone]
Agilent website (all countries)
To find contact information for your location, click the
following link, select your country, and then click Go.
http://www.chem.agilent.com/en- us/ContactUS/Pages/Contact
Us.aspx

10 400/54 Premium Shielded NMR Magnet System Product Overview
1Introduction
Important Notice
Inspect goods immediately on arrival for possible transit
damage, and notify Agilent Technologies within three days of
receipt of goods. Failure to do this invalidates any possible
claim.
Disclaimer
Every precaution has been taken in the preparation of this
publication. Agilent Technologies assumes no responsibility
for errors or omissions. Neither is any liability assumed for
damages resulting from the use of the information contained
herein.

11
Agilent 400/54 Premium Shielded NMR Magnet System
System Overview
Agilent Technologies
2
Installation and Operation Safety
Introduction 12
Nature of the Magnetic Field 13
Hazards Presented by the Magnetic Field 14
Magnetic Field Safety Requirements 15
Nature of Liquid Cryogens 17
Hazards Presented by Cryogens 18
Siting Requirements 20
Electrical Safety 23
Safe Access When Working at Height 24
Considerations for the Outbreak of Fire 25
General Safety — Potential Hazards 27

12 400/54 Premium Shielded NMR Magnet System Product Overview
2Installation and Operation Safety
Introduction
The site for a superconducting magnet system must meet
national, state, and local safety regulations. For magnet
systems, site safety issues primarily relate to magnetic fringe
fields and handling liquid cryogens. This section summarizes
these potential dangers and makes recommendations for the
facility.

Installation and Operation Safety 2
400/54 Premium Shielded NMR Magnet System Product Overview 13
Nature of the Magnetic Field
The greatest hazard presented by a superconducting magnet
is the fringe magnetic field. Once the magnet is energized,
the magnetic field is always present, even when all power to
the system is turned off. This magnetic field extends above,
below and to the sides of the magnet. It extends through
doors, walls ceilings, and floors.
The strength of the magnetic field increases as the magnet is
approached. Objects and people at risk from the magnetic
field are considered safe outside the 5 gauss line.
Occasionally, fault conditions cause magnets to lose their
superconducting properties, which in turn causes their
magnetic fields to collapse. For a magnet that is actively
shielded, before the magnetic field collapses it can
momentarily “bloom” slightly beyond its normal dimensions.
For further details on this subject for any specific magnet,
consult Agilent Technologies.
NOTE
A magnet that has been de-energized but remains at liquid helium
temperatures still exhibits a small residual magnetic field. Make
measurements of this field, and restrict public access as per national and
state requirements. (See “Magnetic Field Safety Requirements” on
page 15.)

14 400/54 Premium Shielded NMR Magnet System Product Overview
2Installation and Operation Safety
Hazards Presented by the Magnetic Field
The strong magnetic field creates hazards because it strongly
attracts ferromagnetic metal alloys. Ferromagnetic metal
alloys contain iron, nickel, or cobalt. They are used in most
types of tools and equipment and in some surgical implants.
The strong magnetic field can cause the following hazards:
•Projectiles
•Displacement of surgical implants
•Stoppage of electrical and mechanical implants and
devices
WARNING
If a loose metal object (such as a wrench or pen) gets too close to
the magnet, it can become a projectile as the force of the
magnetic field pulls the object towards the magnetic center. This
metal projectile can seriously injure anyone standing between it
and the magnet.
WARNING
Ferromagnetic metals are sometimes used in surgical implants
and prosthetic devices. The magnetic field can twist metallic
implants out of place, causing tissue damage and pain to the
person in whom they are implanted, creating a life-threatening
situation. Some cardiac pacemakers, biostimulators, and
neurostimulators are mechanically activated and can stop in the
presence of the magnetic field. This situation can also create a
life-threatening situation.

Installation and Operation Safety 2
400/54 Premium Shielded NMR Magnet System Product Overview 15
Magnetic Field Safety Requirements
Control the hazards described in the previous sections of
this document by establishing two secure and clearly marked
zones:
•The Exclusion Zone
•The Magnetic Attraction Zone
Exclusion Zone (5-gauss line)
The exclusion zone comprises the area (rooms and hallways
for example) inside the 5- gauss line of the magnet. Prevent
individuals with cardiac or other mechanically active
implants from entering this area.
The magnetic field surrounds the magnet in a
three- dimensional fashion. Limit access and warn individuals
who are potentially at risk, not only at the same floor as the
magnet, but also at the levels above and below the magnet.
Enforce the exclusion zone with a combination of warning
signs and physical barriers. The following figure shows the
warning sign recommended by Agilent Technologies.
NOTE
National and state legislation & requirements differ around the world. In
the USA, follow the requirements and guidance issued by the Food & Drug
Administration (FDA). In Europe, European Commission (EC) Directive
2004/40/EC applies; follow the guidance issued by the International
Commission on Non Ionizing Radiation Protection (ICNIRP).
NOTE
Before 1st April 2005, the advisory body for the United Kingdom was the
National Radiological Protection Board (NRPB) - a member of ICNIRP.
From 1st April 2005 the NRPB merged with the United Kingdom Health
Protection Agency (HPA), and became its Radiation Protection Division.

16 400/54 Premium Shielded NMR Magnet System Product Overview
2Installation and Operation Safety
Figure 1 Warning sign
Magnetic Attraction Zone
The “magnetic attraction zone” is established to prevent
ferromagnetic objects from becoming projectiles; it is usually
confined to the room that houses the magnet. The magnetic
attraction zone threshold is usually at a magnetic field
strength of 30 gauss.
Occupational exposure to magnetic fields
Consult national and state enforcement and advisory bodies
to ensure that any exposure limits are not infringed for
(nonpatient) occupational workers.
NOTE
At magnetic field strengths of approximately ten gauss or more, magnetic
media can become wiped or damaged.
WARNING
Do not allow ferromagnetic objects inside the Magnetic Attraction
Zone.

Installation and Operation Safety 2
400/54 Premium Shielded NMR Magnet System Product Overview 17
Nature of Liquid Cryogens
A superconducting magnet uses two types of cryogens: liquid
helium and liquid nitrogen. Helium is a naturally occurring,
inert gas that becomes a liquid at approximately 4K. It is
colorless, odorless, nonflammable, and nontoxic. In order to
remain in a superconducting state, the magnet is immersed
in liquid helium.
Nitrogen is a naturally occurring gas that becomes liquid at
approximately 77K. It is also colorless, odorless,
nonflammable, and nontoxic. It is used to cool the shield
that surrounds the liquid helium reservoir.
During normal operation, liquid cryogens evaporate and
require replenishment on a regular basis.
CAUTION
It
Cryogens are delivered to the site in Dewars; these Dewars,
including any carriers, must be nonmagnetic.

18 400/54 Premium Shielded NMR Magnet System Product Overview
2Installation and Operation Safety
Hazards Presented by Cryogens
Helium and nitrogen in both their liquid and gaseous forms,
present the following hazards:
•A large quantity of gas released in an area that is not
well ventilated can cause asphyxiation.
•Liquids or cold gases can cause cryogenic burns.
•The filling procedure produces an oxygen- rich liquid,
which is a fire hazard when it drops on a combustible
material.
The extremely low temperature of the liquids and their cold
vapors can cause severe frostbite, or a cryogenic burn. These
low temperatures are mainly a danger during the filling
process, when the fill line and other equipment freezes.
To prevent cryogenic burns, wear safety footwear, protective
gloves, and a face shield. Long- sleeved clothing and long
trousers or pants are also recommended.
During the filling process, atmospheric air condenses on the
fill line or pipes, leaving an oxygen- rich liquid, or even
liquid oxygen. If this drips onto a combustible material, like
oil or grease, it can cause a fire.
For these reasons, note the following recommendations:
•Exclude all sources of ignition from magnet rooms.
•Keep all tools and equipment used for transferring
cryogenic liquids clean and free from oils and grease.
•Exclude all sources of ignition from the magnet room,
which is also designated as a No Smoking zone.
WARNING
Touching the fill line or any other piece of equipment during a
transfer can freeze the skin or cause it to stick to the surface of
the equipment.
WARNING
Liquid oxygen can spontaneously ignite upon contact with
oils or greases.