Asus TUF GAMING B650M-PLUS WIFI User manual

Motherboard
TUF GAMING
B650M-PLUS

ii
E20198
First Edition
August 2022
Copyright © 2022 ASUSTeK COMPUTER INC. All Rights Reserved.
No part of this manual, including the products and software described in it, may be reproduced,
transmitted, transcribed, stored in a retrieval system, or translated into any language in any form or by any
means, except documentation kept by the purchaser for backup purposes, without the express written
permission of ASUSTeK COMPUTER INC. (“ASUS”).
Product warranty or service will not be extended if: (1) the product is repaired, modied or altered, unless
such repair, modication of alteration is authorized in writing by ASUS; or (2) the serial number of the
product is defaced or missing.
ASUS PROVIDES THIS MANUAL “AS IS” WITHOUT WARRANTY OF ANY KIND, EITHER EXPRESS
OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE IMPLIED WARRANTIES OR CONDITIONS OF
MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. IN NO EVENT SHALL ASUS, ITS
DIRECTORS, OFFICERS, EMPLOYEES OR AGENTS BE LIABLE FOR ANY INDIRECT, SPECIAL,
INCIDENTAL, OR CONSEQUENTIAL DAMAGES (INCLUDING DAMAGES FOR LOSS OF PROFITS,
LOSS OF BUSINESS, LOSS OF USE OR DATA, INTERRUPTION OF BUSINESS AND THE LIKE),
EVEN IF ASUS HAS BEEN ADVISED OF THE POSSIBILITY OF SUCH DAMAGES ARISING FROM ANY
DEFECT OR ERROR IN THIS MANUAL OR PRODUCT.
SPECIFICATIONS AND INFORMATION CONTAINED IN THIS MANUAL ARE FURNISHED FOR
INFORMATIONAL USE ONLY, AND ARE SUBJECT TO CHANGE AT ANY TIME WITHOUT NOTICE,
AND SHOULD NOT BE CONSTRUED AS A COMMITMENT BY ASUS. ASUS ASSUMES NO
RESPONSIBILITY OR LIABILITY FOR ANY ERRORS OR INACCURACIES THAT MAY APPEAR IN THIS
MANUAL, INCLUDING THE PRODUCTS AND SOFTWARE DESCRIBED IN IT.
Products and corporate names appearing in this manual may or may not be registered trademarks or
copyrights of their respective companies, and are used only for identication or explanation and to the
owners’ benet, without intent to infringe.

iii
Contents
Safety information...................................................................................................... iv
About this guide.......................................................................................................... v
Package contents....................................................................................................... vi
TUF GAMING B650M-PLUS specications summary ............................................. vi
Chapter 1 Product Introduction
1.1 Before you proceed...................................................................................... 1-1
1.2 Motherboard overview ................................................................................. 1-1
1.3 Central Processing Unit (CPU).................................................................... 1-9
1.4 System memory.......................................................................................... 1-10
1.5 M.2 installation............................................................................................ 1-12
Chapter 2 BIOS and RAID Support
2.1 Knowing BIOS............................................................................................... 2-1
2.2 BIOS Setup program .................................................................................... 2-2
2.3 ASUS EZ Flash 3........................................................................................... 2-3
2.4 ASUS CrashFree BIOS 3.............................................................................. 2-4
2.5 RAID congurations..................................................................................... 2-5
Appendix
Notices ..................................................................................................................... A-1
Warranty................................................................................................................... A-7
ASUS contact information...................................................................................... A-9
Service and Support ............................................................................................... A-9

iv
Safety information
Electrical safety
• To prevent electrical shock hazard, disconnect the power cable from the electrical outlet
before relocating the system.
• When adding or removing devices to or from the system, ensure that the power cables
for the devices are unplugged before the signal cables are connected. If possible,
disconnect all power cables from the existing system before you add a device.
• Before connecting or removing signal cables from the motherboard, ensure that all power
cables are unplugged.
• Seek professional assistance before using an adapter or extension cord. These devices
could interrupt the grounding circuit.
• Ensure that your power supply is set to the correct voltage in your area. If you are not
sure about the voltage of the electrical outlet you are using, contact your local power
company.
• If the power supply is broken, do not try to x it by yourself. Contact a qualied service
technician or your retailer.
Operation safety
• Before installing the motherboard and adding components, carefully read all the manuals
that came with the package.
• Before using the product, ensure all cables are correctly connected and the power cables
are not damaged. If you detect any damage, contact your dealer immediately.
• To avoid short circuits, keep paper clips, screws, and staples away from connectors,
slots, sockets and circuitry.
• Avoid dust, humidity, and temperature extremes. Do not place the product in any area
where it may become wet.
• Place the product on a stable surface.
• If you encounter technical problems with the product, contact a qualied service
technician or your retailer.
• Your motherboard should only be used in environments with ambient temperatures
between 0°C and 40°C.
Button/Coin Batteries Safety Information
WARNING
KEEP OUT OF REACH OF CHILDREN
Swallowing can lead to chemical burns,
perforation of soft tissue, and death.
Severe burns can occur within 2 hours
of ingestion. Seek medical attention
immediately.

v
About this guide
This user guide contains the information you need when installing and conguring the
motherboard.
How this guide is organized
This guide contains the following parts:
• Chapter 1: Product Introduction
This chapter describes the features of the motherboard and the new technology it
supports. It includes descriptions of the switches, jumpers, and connectors on the
motherboard.
• Chapter 2: BIOS and RAID Support
This chapter tells how to boot into the BIOS, upgrade BIOS using the EZ Flash Utility
and support on RAID.
Where to nd more information
Refer to the following sources for additional information and for product and software
updates.
1. ASUS website
The ASUS website (www.asus.com) provides updated information on ASUS hardware
and software products.
2. Optional documentation
Your product package may include optional documentation, such as warranty flyers,
that may have been added by your dealer. These documents are not part of the
standard package.
Conventions used in this guide
To ensure that you perform certain tasks properly, take note of the following symbols used
throughout this guide.
CAUTION: Information to prevent damage to the components and injuries to yourself when
trying to complete a task.
IMPORTANT: Instructions that you MUST follow to complete a task.
NOTE: Tips and additional information to help you complete a task.

vi
TUF GAMING B650M-PLUS specications summary
CPU AMD Socket AM5 for AMD Ryzen™ 7000 Series Desktop Processors*
* Refer to www.asus.com for CPU support list.
Chipset AMD B650 Chipset
Memory
4 x DIMM, Max. 128GB, DDR5 6400+(OC)/ 6200(OC)/ 6000(OC)/ 5800(OC)/
5600(OC)/ 5400(OC)/ 5200/ 5000/ 4800 ECC & Non-ECC,
Un-buffered Memory*
Dual Channel Memory Architecture
Supports AMD EXTended Proles for Overclocking (EXPO™)
OptiMem II
* Non-ECC, Un-buffered DDR5 Memory supports On-Die ECC function
* Supported memory types, data rate(Speed), and number of DRAM modules vary
depending on the CPU and memory conguration, for more information refer to
www.asus.com for memory support list.
Graphics
1 x DisplayPort**
1 x HDMI® port***
* Graphics specications may vary between CPU types.
** Supports max. 8K@60Hz as specied in DisplayPort 1.4.
***Supports 4K@60Hz as specied in HDMI 2.1.
Expansion Slots
AMD Ryzen™ 7000 Series Desktop Processors*
1 x PCIe 4.0 x16 slot
AMD B650 Chipset
1 x PCIe 4.0 x16 slot (supports x4 mode)
1 x PCIe 4.0 x1 slot
* Please check PCIe bifurcation table in support site
(https://www.asus.com/support/FAQ/1037507/).
Note: To ensure compatibility of the device installed, please refer to
https://www.asus.com/support/ for the list of supported peripherals.
Storage
Total supports 2 x M.2 slots and 4 x SATA 6Gb/s ports*
AMD Ryzen™ 7000 Series Desktop Processors
M.2_1 slot (Key M), type 2242/2260/2280 (supports PCIe 5.0 x4 mode)
M.2_2 slot (Key M), type 2242/2260/2280 (supports PCIe 4.0 x4 mode)
AMD B650 Chipset
4 x SATA 6Gb/s ports
* AMD RAIDXpert2 Technology supports both PCIe RAID 0/1/10 and SATA RAID
0/1/10.
Package contents
Check your motherboard package for the following items.
Motherboard 1 x TUF GAMING B650M-PLUS motherboard
Cables 2 x SATA 6Gb/s cables
Miscellaneous 1 x M.2 Rubber Package
1 x M.2 SSD Screw package
Documentation 1 x TUF Certication card
1 x User guide
If any of the above items is damaged or missing, contact your retailer.
(continued on the next page)

vii
TUF GAMING B650M-PLUS specications summary
Ethernet 1 x Realtek 2.5Gb Ethernet
TUF LANGuard
USB
Rear USB (Total 8 ports)
1 x USB 3.2 Gen 2x2 port (1 x USB Type-C®)
2 x USB 3.2 Gen 2 ports (2 x Type-A)
1 x USB 3.2 Gen 1 port (1 x Type-A)
4 x USB 2.0 ports (4 x Type-A)
Front USB (Total 7 ports)
1 x USB 3.2 Gen 1 connector (supports USB Type-C®)
1 x USB 3.2 Gen 1 header supports 2 additional USB 3.2 Gen 1 ports
2 x USB 2.0 headers support 4 additional USB 2.0 ports
Audio
Realtek 7.1 Surround Sound High Denition Audio CODEC
- Supports: Jack detection, Multi-streaming, Front Panel Jack-retasking
- Supports up to 24-Bit/192 kHz playback
Audio Features
- Audio Shielding
- Premium audio capacitors
- Dedicated audio PCB layers
Back Panel I/O Ports
1 x USB 3.2 Gen 2x2 port (1 x USB Type-C®)
2 x USB 3.2 Gen 2 ports (2 x Type-A)
1 x USB 3.2 Gen 1 port (1 x Type-A)
4 x USB 2.0 ports (4 x Type-A)
1 x DisplayPort
1 x HDMI®port
1 x Realtek 2.5Gb Ethernet port
5 x Audio jacks
1 x BIOS FlashBack™ button
Internal I/O
Connectors
Fan and Cooling related
1 x 4-pin CPU Fan header
1 x 4-pin CPU OPT Fan header
1 x 4-pin AIO Pump header
3 x 4-pin Chassis Fan headers
Power related
1 x 24-pin Main Power connector
1 x 8-pin +12V Power connector
1 x 4-pin +12V Power connector
Storage related
2 x M.2 slots (Key M)
4 x SATA 6Gb/s ports
USB
1 x USB 3.2 Gen 1 connector (supports USB Type-C®)
1 x USB 3.2 Gen 1 header supports 2 additional USB 3.2 Gen 1 ports
2 x USB 2.0 headers support 4 additional USB 2.0 ports
(continued on the next page)

viii
TUF GAMING B650M-PLUS specications summary
Internal I/O
Connectors
Miscellaneous
3 x Addressable Gen 2 headers
1 x Aura RGB header
1 x Clear CMOS header
1 x COM Port header
1 x Front Panel Audio header (AAFP)
1 x 20-3 pin System Panel header with Chassis intrude function
1 x Thunderbolt™ header
Special Features
ASUS TUF PROTECTION
- DIGI+ VRM (Digital power design with DrMOS)
- Enhanced DRAM Overcurrent Protection
- ESD Guards
- TUF LANGuard
- Overvoltage Protection
- SafeSlot Core+
- Stainless-Steel Back I/O
ASUS Q-Design
- M.2 Q-Latch
- Q-DIMM
- Q-LED (CPU [red], DRAM [yellow], VGA [white], Boot Device [yellow
green])
- Q-Slot
ASUS Thermal Solution
- M.2 heatsink
- VRM heatsink design
ASUS EZ DIY
- BIOS FlashBack™ button
- BIOS FlashBack™ LED
- ProCool
- Pre-mounted I/O shield
- SafeDIMM
Aura Sync
- Aura RGB header
- Addressable Gen 2 headers
Software
Features
ASUS Exclusive Software
Armoury Crate
- Aura Creator
- Aura Sync
- Fan Xpert 2+
- Power Saving
- Two-Way AI Noise Cancelation
AI Suite 3
- TurboV EVO
- DIGI+ VRM
- PC Cleaner
(continued on the next page)

ix
TUF GAMING B650M-PLUS specications summary
Software
Features
TUF GAMING CPU-Z
DTS Audio Processing
Norton Anti-virus software (Free Trial version)
WinRAR
UEFI BIOS
ASUS EZ DIY
- ASUS CrashFree BIOS 3
- ASUS EZ Flash 3
- ASUS UEFI BIOS EZ Mode
BIOS 256 Mb Flash ROM, UEFI AMI BIOS
Manageability WOL by PME, PXE
Operating
System Windows®11, Windows®10 64-bit
Form Factor mATX Form Factor
9.6 inch x 9.6 inch (24.4 cm x 24.4 cm)

x

1-1
1
Product Introduction
1.1 Before you proceed
Take note of the following precautions before you install motherboard components or change
any motherboard settings.
• Unplug the power cord from the wall socket before touching any component.
• Before handling components, use a grounded wrist strap or touch a safely grounded
object or a metal object, such as the power supply case, to avoid damaging them due
to static electricity.
• Hold components by the edges to avoid touching the ICs on them.
• Whenever you uninstall any component, place it on a grounded antistatic pad or in the
bag that came with the component.
• Before you install or remove any component, ensure that the ATX power supply is
switched off or the power cord is detached from the power supply. Failure to do so
may cause severe damage to the motherboard, peripherals, or components.
Unplug the power cord before installing or removing the motherboard. Failure to do so can
cause you physical injury and damage motherboard components.
The pin denitions in this chapter are for reference only. The pin names depend on the
location of the header/jumper/connector.
1.2 Motherboard overview
7
DDR5 DIMM_A1 (64bit, 288-pin module) DDR5 DIMM_A2 (64bit, 288-pin module) DDR5 DIMM_B1 (64bit, 288-pin module) DDR5 DIMM_B2 (64bit, 288-pin module)
CPU
DRAM
VGA
BOOT
CPU_OPT
AIO_PUMP
CPU_FAN
CHA_FAN2
CHA_FAN3
CHA_FAN1
COM PANEL
AAFP
SATA6G_1SATA6G_2SATA6G_3
ATX_PWR
U32G1_89
Super
I/O
2280 2260 2242
2280 2260 2242
PCIEX16_1
PCIEX16_2
PCIEX1
USB_1415 USB_1617
RGB_HEADER
ADD_GEN 2_3 CLRTC
U32G1_2
LAN_USB_11_13
USB_1_5
U32G2_34
U32G2X2_C6
HDMI_DP DIGI
+VRM
24.4cm(9.6in)
24.4cm(9.6in)
BATTERY
U32_C10
COM_DEBUG
SOCKET AM5
ATX_12V_2 ATX_12V_1
TB_HEADER
AMD
B650
X
PCIE SATA
4.0 X4
PCIE SATA
5.0 X4 X
M.2_1(SOCKET3)
Audio
Codec
Ethernet
256Mb
BIOS
ADD_GEN 2_1
ADD_GEN 2_2
1st
AUDIO
BIOS_FLBK
FLBK_LED
SATA6G_4
M.2_2(SOCKET3) M.2_1(SOCKET3)
M.2_2(SOCKET3)
5
19
8
6
9
1415
18
3
4
2
4 1115
161110 1274
7
13
17
Place this
side towards
the rear of the
chassis
ASUS TUF GAMING B650M-PLUS

1-2
1.2.1 Layout contents
1. CPU socket
The motherboard comes with an AMD Socket AM5 designed for AMD Ryzen™ 7000 Series
Desktop Processors.
For more details, refer to Central Processing Unit (CPU).
2. DDR5 DIMM slots
The motherboard comes with Dual Inline Memory Modules (DIMM) slots designed for DDR5
(Double Data Rate 5) memory modules.
For more details, refer to System memory.
3. Expansion slots
This motherboard supports two PCIe x16 graphics cards and one PCIe 3.0 x1 network card,
SCSI card or other card that comply with the PCI Express specication.
• Additional PCIe bifurcation and M.2 settings for RAID function are also supported
when a Hyper M.2 x16 series card is installed.
• For full details on the PCIe bifurcation, you may visit the support site at
https://www.asus.com/support/FAQ/1037507/.
• The Hyper M.2 x16 series card is sold separately.
• Adjust the PCIe bifurcation under BIOS settings.
4. Fan headers
The Fan headers allow you to connect fans to cool the
system.
Header Max.
Current
Max.
Power Default Speed Shared
Control
CPU_FAN 1A 12W Q-Fan Controlled A
CPU_OPT 1A 12W Q-Fan Controlled A
CHA_FAN1 1A 12W Q-Fan Controlled -
CHA_FAN2 1A 12W Q-Fan Controlled -
CHA_FAN3 1A 12W Q-Fan Controlled -
AIO_PUMP 1A 12W Full-Speed -
5. Power connectors
These Power connectors allow you to connect your motherboard to a power supply. The
power supply plugs are designed to t in only one orientation. Find the proper orientation and
push down rmly until the power supply plugs are fully inserted.
Ensure to connect the 8-pin power plug.
FAN PWM
FAN IN
FAN PWR
GND
GND
FAN PWR
FAN IN
FAN PWM
FAN PWM
FAN IN
FAN PWR
GND
GND FAN PWR FAN IN FAN PWM
Chapter 1: Product Introduction

1-3
• For a fully congured system, we recommend that you use a power supply unit
(PSU) that complies with ATX 12V Specication 2.0 (or later version) and provides a
minimum power of 350W.
• We recommend that you use a PSU with a higher power output when conguring a
system with more power-consuming devices. The system may become unstable or
may not boot up if the power is inadequate.
• If you are uncertain about the minimum power supply requirement for your system, we
recommend you to refer to online resources for Power Supply Wattage Calculator.
6. M.2 slots (Key M)
The M.2 slots allow you to install M.2 devices such as M.2 SSD modules.
For AMD Ryzen™ 7000 Series Desktop Processors:
M.2_1 slot (Key M), type 2242/2260/2280 (supports PCIe 5.0 x4 mode)
M.2_2 slot (Key M), type 2242/2260/2280 (supports PCIe 4.0 x4 mode)
7. SATA 6Gb/s ports
The SATA 6Gb/s ports allow you to connect SATA devices such as optical disc drives and
hard disk drives via SATA cables.
8. USB 3.2 Gen 1 Type-C®Front Panel connector
The USB 3.2 Gen 1 Type-C® connector allows you to connect a USB
3.2 Gen 1 module for an additional USB 3.2 Gen 1 Type-C®port. The
connector provides a data transfer speed of up to 5 Gb/s.
The USB 3.2 Gen 1 Type-C®module is purchased separately.
9. USB 3.2 Gen 1 header
The USB 3.2 Gen 1 header allows you to connect a USB 3.2 Gen
1 module for additional USB 3.2 Gen 1 ports. The USB 3.2 Gen 1
header provides data transfer speeds of up to 5 Gb/s.
The USB 3.2 Gen 1 module is purchased separately.
10. USB 2.0 headers
The USB 2.0 headers allow you to connect a USB module for additional USB
2.0 ports. The USB 2.0 headers provide data transfer speeds of up to 480
Mb/s.
DO NOT connect a 1394 cable to the USB connectors. Doing so will
damage the motherboard!
The USB 2.0 module is purchased separately.
SBU2
SBU1
CC1
VBUS
RX1-
RX1+
GND
TX1-
TX1+
VBUS
VBUS
TX2+
TX2-
GND
RX2+
RX2-
GND
D-
D+
CC2
USB3+5V
IntA_P1_SSRX-
IntA_P1_SSRX+
GND
IntA_P1_SSTX-
IntA_P1_SSTX+
GND
IntA_P1_D-
IntA_P1_D+
GND
PIN 1
USB3+5V
IntA_P2_SSRX-
IntA_P2_SSRX+
GND
IntA_P2_SSTX-
IntA_P2_SSTX+
GND
IntA_P2_D-
IntA_P2_D+
USB+5V USB_E1- USB_E1+ GND NC
USB+5V
USB_E2-
USB_E2+
GND
PIN 1
ASUS TUF GAMING B650M-PLUS

1-4
Before you install or remove any component, ensure that the power supply is switched off
or the power cord is detached from the power supply. Failure to do so may cause severe
damage to the motherboard, peripherals, or components.
• Actual lighting and color will vary with LED strip.
• If your LED strip does not light up, check if the addressable RGB LED strip is
connected in the correct orientation, and the 5V connector is aligned with the 5V
header on the motherboard.
• The addressable RGB LED strip will only light up when the system is powered on.
• The addressable RGB LED strip is purchased separately.
12. Aura RGB header
The RGB header allows you to connect RGB LED strips.
The RGB header supports 5050 RGB multi-color LED strips (12V/G/R/B), with a maximum
power rating of 3A (12V), and no longer than 3m.
Before you install or remove any component, ensure that the ATX power supply is switched
off or the power cord is detached from the power supply. Failure to do so may cause severe
damage to the motherboard, peripherals, or components.
• Actual lighting and color will vary with LED strip.
• If your LED strip does not light up, check if the RGB LED extension cable and the
RGB LED strip are connected in the correct orientation, and the 12V connector is
aligned with the 12V header on the motherboard.
• The LED strip will only light up when the system is powered on.
• The LED strip is purchased separately.
13. Clear CMOS header
This header allows you to clear the CMOS RTC RAM data of the system setup
information such as date, time, and system passwords.
To erase the RTC RAM:
1. Turn OFF the computer and unplug the power cord.
2. Use a metal object such as a screwdriver to short the two pins.
3. Plug the power cord and turn ON the computer.
4. Hold down the <Del> key during the boot process and enter BIOS setup to re-
enter data.
CLRTC
+3V_BAT GND
PIN 1
11. Addressable Gen 2 headers
The Addressable Gen 2 headers allow you to connect individually
addressable RGB WS2812B LED strips or WS2812B based LED strips.
The Addressable Gen 2 headers support WS2812B addressable RGB
LED strips (5V/Data/Ground), with a maximum power rating of 3A (5V),
and the addressable headers on this board can handle a combined
maximum of 500 LEDs.
+5V
Data
Ground
PIN 1
ADD_GEN 2
Chapter 1: Product Introduction

1-5
14. COM Port header
This header is for a serial (COM) port. Connect the serial port module cable
to this header, then install the module to a slot opening at the back of the
system chassis.
15. Front Panel Audio header
This header is for a chassis-mounted front panel audio I/O module that
supports HD audio standard. Connect one end of the front panel audio I/O
module cable to this header.
• We recommend that you connect a high-denition front panel
audio module to this header to avail of the motherboard’s high-
denition audio capability.
• If you want to connect a high-denition front panel audio module
to this header, set the Front Panel Type item in the BIOS setup
to [HD Audio]. By default, this header is set to [HD Audio].
16. System Panel header
This header supports several chassis-mounted functions.
• System Power LED header (PLED)
The 2-pin and/or 3-1 pin headers allow you to connect the
System Power LED. The System Power LED lights up when
the system is connected to a power source, or when you
turn on the system power, and blinks when the system is in
sleep mode.
• Storage Device Activity LED header (HDD_LED)
The 2-pin header allows you to connect the Storage Device Activity LED. The Storage
Device Activity LED lights up or blinks when data is read from or written to the storage
device or storage device add-on card.
• System Warning Speaker header (SPEAKER)
The 4-pin header allows you to connect the chassis-mounted system warning speaker.
The speaker allows you to hear system beeps and warnings.
• Power Button/Soft-off Button header (PWRSW)
The 3-1 pin header allows you to connect the system power button. Press the
power button to power up the system, or put the system into sleep or soft-off mode
(depending on the operating system settings).
• Reset button header (RESET)
The 2-pin header allows you to connect the chassis-mounted reset button. Press the
reset button to reboot the system.
PIN 1
COM
DCD
TXD
GND
RTS
RI
RXD
DTR
DSR
CTS
AAFP
AGND NC SENSE1_RETUR SENSE2_RETUR
PORT1 L
PORT1 R PORT2 R
SENSE_SEND
PORT2 L
HD-audio-compliant
pin definition
If the steps above do not help, remove the onboard battery and short the two pins again to
clear the CMOS RTC RAM data. After clearing the CMOS, reinstall the battery.
ASUS TUF GAMING B650M-PLUS

1-6
17. Thunderbolt™ header
The Thunderbolt™ header allows you to connect an add-on
Thunderbolt™ I/O card that supports Intel®’s Thunderbolt™
Technology, allowing you to connect Thunderbolt™-enabled
devices to form a daisy-chain conguration.
• The add-on Thunderbolt™ I/O card and
Thunderbolt™ cables are purchased separately.
• Please visit the official website of your purchased
Thunderbolt™ card for more details on compatibility.
The Thunderbolt™ card can only be used when installed to the PCIEX16_2 slot. Ensure to
install your Thunderbolt™ card to the PCIEX16_2 slot.
18. BIOS FlashBackTM LED
The BIOS FlashBack™ LED lights up or blinks to indicate the status of
the BIOS FlashBack™.
Scan the QR code for more information on BIOS FlashBackTM
function.
19. Q-LEDs
The Q-LEDs check key components (CPU, DRAM, VGA, and booting devices) during the
motherboard booting process. If an error is found, the critical component’s LED stays lit up
until the problem is solved.
The Q-LEDs provide the most probable cause of an error code as a starting point for
troubleshooting. The actual cause may vary from case to case.
PIN 1
FORCE_PWR
TB_CIO_PLUG_EVENT
SLP_S3# SLP_S5#
GND
RTD3_SW
I2C_SCL I2C_SDA I2C_IRQ# RTD3_POWER_EN NC PERST_N WAKE#
TB_HEADER
• Chassis intrusion header (CHASSIS)
The 2-pin header allows you to connect the chassis-mounted intrusion detection
sensor or switch. The chassis intrusion sensor or switch sends a high-level signal
to the header when a chassis component is removed or replaced, the signal is then
generated as a chassis intrusion event.
Chapter 1: Product Introduction

1-7
1.2.2 Rear panel connectors
1. DisplayPort. This port is for a DisplayPort-compatible device.
2. USB 3.2 Gen 2 (up to 10Gbps) ports (teal blue, Type A). These 9-pin Universal
Serial Bus 3.2 (USB 3.2) ports are for USB 3.2 Gen 2 devices.
3. USB 2.0 ports. These 4-pin Universal Serial Bus (USB) ports are for USB 2.0 devices.
4. USB 3.2 Gen 1 (up to 5Gbps) port. This 9-pin Universal Serial Bus (USB) port
connects to USB 3.2 Gen 1 devices.
5. 2.5G Ethernet port. This port allows 2.5Gbps Ethernet connection to a Local Area
Network (LAN) through a network hub. Refer to the table below for the Ethernet port
LED indications.
Speed LED
Status Description
OFF No link
GREEN 2.5 Gbps connection
ORANGE 1 Gbps / 100 Mbps /
10 Mbps connection
Activity Link LED
Status Description
OFF No link
GREEN Linked
BLINKING Data activity
Realtek 2.5G Ethernet port LED indications
ACT/LINK
LED
SPEED
LED
Ethernet port
6. Center / Subwoofer port (orange). This port connects the center/subwoofer speakers.
7. Rear Speaker Out port (black). This port connects the rear speakers in a 4 channel,
5.1 channel, or 7.1 channel audio conguration.
8. Line In port (light blue). This port connects the tape, CD, DVD player, or other audio
sources.
9. HDMI®port. This port is for a High-Denition Multimedia Interface (HDMI®) connector,
and is HDCP compliant allowing playback of HD DVD, Blu-ray, and other protected
content.
10. USB 3.2 Gen 2x2 (up to 20Gbps) port (USB Type-C®). This 9-pin Universal Serial
Bus 3.2 (USB 3.2) port is for USB 3.2 Gen 2x2 Type-C®devices.
9 10 3
1 4 5 6 7 82 3
12 13 14
11
ASUS TUF GAMING B650M-PLUS

1-8
11. USB 2.0 port with BIOS FlashBackTM function. Insert a USB storage device to this
Universal Serial Bus (USB) port to run BIOS FlashBackTM.
12. BIOS FlashBackTM button. BIOS FlashBack™ allows you to easily update the BIOS
without entering the existing BIOS or operating system.
To use BIOS FlashBack™:
1) Insert a USB storage device to the BIOS FlashBack™ port.
2) Visit https://www.asus.com/support/ and download the latest BIOS version for this
motherboard.
3) Manually rename the le as TG650MP.CAP, or launch the BIOSRenamer.exe
application to automatically rename the le, then copy it to your USB storage device.
The BIOSRenamer.exe application is zipped together with your BIOS le when you
download a BIOS le for a BIOS FlashBack™ compatible motherboard.
4) Shut down your computer.
5) Press the BIOS FlashBack™ button for three (3) seconds until the BIOS FlashBack™
LED blinks three times, indicating that the BIOS FlashBack™ function is enabled.
6) Wait until the light goes out, indicating that the BIOS updating process is completed.
13. Microphone port (pink). This port connects a microphone.
14. Line Out port (lime). This port connects a headphone or a speaker. In 4-channel,
5.1-channel, and 7.1-channel congurations, the function of this port becomes Front
Speaker Out.
Refer to the audio conguration table for the function of the audio ports in 2, 4, 5.1, or
7.1-channel conguration.
Audio 2, 4, 5.1 or 7.1-channel conguration
Port 2-channel 4-channel 5.1-channel 7.1-channel
Light Blue
(Rear panel) ---Side Speaker Out
Lime
(Rear panel)
Front Speaker
Out
Front Speaker
Out
Front Speaker
Out
Front Speaker
Out
Pink
(Rear panel) ----
Black
(Rear panel) -Rear Speaker Out
Rear Speaker
Out
Rear Speaker
Out
Orange
(Rear panel) - - Center/ Subwoofer
Center/
Subwoofer
Chapter 1: Product Introduction

1-9
1.3 Central Processing Unit (CPU)
The motherboard comes with a Socket AM5 designed for AMD Ryzen™
7000 Series Desktop Processors.
Unplug all power cables before installing the CPU.
• The AM5 socket has a different pinout design. Ensure that you
use a CPU designed for the AM5 socket.The CPU fits in only one correct orientation.
DO NOT force the CPU into the socket to prevent bending the connectors on the
socket and damaging the CPU.
• ASUS will not cover damages resulting from incorrect CPU installation/removal,
incorrect CPU orientation/placement, or other damages resulting from negligence by
the user.
ASUS TUF GAMING B650M-PLUS
Installing the CPU
Apply the Thermal Interface Material to the CPU heatsink and CPU before you install the
heatsink and fan if necessary.

1-10
1.4 System memory
The motherboard comes with Dual Inline Memory Modules (DIMM) slots designed for DDR5
(Double Data Rate 5) memory modules.
A DDR5 memory module is notched differently from a DDR, DDR2, DDR3 or DDR4
module. DO NOT install a DDR, DDR2, DDR3 or DDR4 memory module to the DDR5 slot.
DIMM_B2
DIMM_B1
DIMM_A2
DIMM_A1
Channel Sockets
Channel A DIMM_A1 & DIMM_A2
Channel B DIMM_B1 & DIMM_B2
• You may install varying memory sizes in Channel A and Channel B. The system
maps the total size of the lower-sized channel for the dual-channel conguration. Any
excess memory from the higher-sized channel is then mapped for single-channel
operation.
• A DDR5 memory module is notched differently from a DDR, DDR2, DDR3 or DDR4
module. DO NOT install a DDR, DDR2, DDR3 or DDR4 memory module to the DDR5
slot.
• The default memory operation frequency is dependent on its Serial Presence Detect
(SPD), which is the standard way of accessing information from a memory module.
Under the default state, some memory modules for overclocking may operate at a
lower frequency than the vendor-marked value.
• For system stability, use a more efcient memory cooling system to support a full
memory load.
• Always install DIMMs with the same CAS latency. For optimal compatibility, we
recommend that you install memory modules of the same version or date code (D/C)
from the same vendor. Check with the retailer to get the correct memory modules.
• Refer to www.asus.com for the Memory QVL (Qualied Vendors Lists), and memory
frequency support depends on the CPU types.
Recommended memory congurations
Chapter 1: Product Introduction