AXIOMTEK MANO561 Series User manual

Disclaimers
This manual has been carefully checked and believed to contain accurate information.
Axiomtek Co., Ltd. assumes no responsibility for any infringements of patents or any third
party’s rights, and any liability arising from such use.
Axiomtek does not warrant or assume any legal liability or responsibility for the accuracy,
completeness, or usefulness of any information in this document. Axiomtek does not make any
commitment to update the information in this manual.
Axiomtek reserves the right to change or revise this document and/or product at any time
without notice.
No part of this document may be reproduced, stored in a retrieval system, or transmitted, in any
form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without
the prior written permission of Axiomtek Co., Ltd.
CAUTION
If you replace wrong batteries, it causes the danger of explosion. It is recommended by the
manufacturer that you follow the manufacturer’s instructions to only replace the same or
equivalent type of battery and dispose of used ones.
Copyright 2022 Axiomtek Co., Ltd.
All Rights Reserved
Octorber 2022, Version A2
Printed in Taiwan
MANO561 Series
Intel® Socket 1700 CoreTM i9/ i7/ i5/ i3
Processors Mini ITX Motherboard
User’s Manual

ii
ESD Precautions
Computer boards have integrated circuits sensitive to static electricity. To prevent chipsets from
electrostatic discharge damage, please take care of the following jobs with precautions:
 Do not remove boards or integrated circuits from their anti-static packaging until you are
ready to install them.
 Before holding the board or integrated circuit, touch an unpainted portion of the system
unit chassis for a few seconds. It discharges static electricity from your body.
 Wear a wrist-grounding strap, available from most electronic component stores, when
handling boards and components.
Trademarks Acknowledgments
Axiomtek is a trademark of Axiomtek Co., Ltd.
Intel® and Celeron® are trademarks of Intel Corporation.
Windows® is a trademark of Microsoft Corporation.
AMI is a trademark of American Megatrend Inc.
IBM, PC/AT, PS/2, VGA are trademarks of International Business Machines Corporation.
Other brand names and trademarks are the properties and registered brands of their respective
owners.

iii
Table of Contents
Disclaimers ....................................................................................................... i
ESD Precautions .............................................................................................. ii
Section 1 Introduction ............................................. 1
1.1 Features ................................................................................................ 2
1.2 Specifications ........................................................................................ 2
1.3 Utilities Supported ................................................................................. 3
1.4 Block Diagram ....................................................................................... 4
Section 2 Board and Pin Assignments .................... 5
2.1 Board Layout ......................................................................................... 5
2.2 Rear I/O ................................................................................................. 7
2.3 Jumper Settings .................................................................................... 8
2.3.1 COM1 Data/Power Select (JP1) ................................................................. 8
2.3.2 Clear CMOS (JP3) ...................................................................................... 8
2.3.3 LVDS VDD Select (JP4) .............................................................................. 9
2.3.4 AT/ATX Power Mode Select (JP5) .............................................................. 9
2.4 Connectors .......................................................................................... 10
2.4.1 COM1 D-Sub Connector (CN1) ................................................................. 11
2.4.2 COM2~COM4 Headers (CN17, CN3~CN4) .............................................. 11
2.4.3 SATA 3.0 Connectors (CN7)...................................................................... 12
2.4.4 SATA Power Connector (CN13) ................................................................ 12
2.4.5 USB 3.2 GEN1 Stack Port (CN10) ............................................................ 12
2.4.6 USB 2.0 Stack Port (CN15) ....................................................................... 13
2.4.7 Ethernet Ports (CN9 and CN12) ............................................................... 13
2.4.8 PCI-Express Mini Card Connector (CN21) ............................................... 13
2.4.9 M.2 Key E Socket (CN22) ......................................................................... 15
2.4.10 Digital I/O Connector (CN26) .................................................................... 16
2.4.11 LVDS Signal Connector (CN29) ................................................................ 16
2.4.12 4-pin ATX Power Input Connectors (CN18) .............................................. 17
2.4.13 HDMI1.4 Connector (CN6) ........................................................................ 17
2.4.14 VGA Connector (CN5) ............................................................................... 18
2.4.15 eDP Connector (CN50) ............................................................................. 18
2.4.16 Audio Header (CN52) ................................................................................ 19
2.4.17 LVDS Backlight Control Header (CN55) ................................................... 19
2.4.19 USB 2.0 Header (CN19) ........................................................................... 19
2.4.20 Front Panel Header (CN8) ........................................................................ 19
2.4.21 SPI Header (CN24) ................................................................................... 21
2.4.22 Audio Jack (CN14) .................................................................................... 21
2.4.23 M.2 Key B Socket (SCN1) ......................................................................... 22

iv
2.4.24 SIM Card Slot (CN25) ............................................................................... 23
Section 3 AMI BIOS Setup Utility .......................... 24
3.1 Starting ................................................................................................ 24
3.2 Navigation Keys .................................................................................. 24
3.3 Main Menu .......................................................................................... 26
3.4 Advanced Menu .................................................................................. 27
3.5 Chipset Menu ...................................................................................... 40
3.6 Boot Menu ........................................................................................... 44
3.7 Security Menu ..................................................................................... 45
3.8 Save & Exit Menu ................................................................................ 47
Appendix A Watchdog Timer ................................... 48
A.1 About Watchdog Timer ........................................................................ 48
A.2 Sample Program ................................................................................. 48
Appendix B Digital I/O ............................................. 50
B.1 About Digital I/O .................................................................................. 50
B.2 Sample Program ................................................................................. 50
Appendix C BIOS Update ........................................ 54
C.1 How to update system BIOS using <F12> key .................................... 54

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MANO561 Mini ITX Motherboard
Introduction 1
Section 1
Introduction
The MANO561 Mini-ITX motherboard supports the new 14nm 12th Generation Intel® Core™ i9
/ i7/ i5 / i3 and Pentium® processors in LGA1700 package. Featuring the new Intel® H610
Express chipset with two DDR4 3200MHz memory support, this motherboard is built to perform
best stability and reliability for industrial applications.
It comes with one SATA 3.0, two USB 3.2 GEN1, five USB 2.0 and four serial ports (one RS-
232/422/485, three RS-232) providing robust storage and I/O options. Users also can increase
board functionality with PCI-Express x16 and full type PCI-Express Mini Card slot. The high
quality MANO561 allows five display interfaces via VGA, HDMI, DisplayPort, LVDS and eDP in
quadruplicate views, making it an ideal solution for gaming, workstation, digital signage,
medical and other IoT&M2M applications.

MANO561 Mini ITX Motherboard
2 Introduction
1.1 Features
 LGA1700 Socket for 12th Generation Intel® Core™ i9/ i7/ i5/ i3 and Pentium® processors
(Alder Lake)
 2 DDR4 3200MHz memory with maximum capacity up to 64 GB
 1 PCI-Express x16
 1 M.2 Key E with size 22x30
 1 full type PCI-Express Mini Card(support SATA, USB 2.0 signal, PCIE x1)
 1 M.2 key B type 2242/3042/3052(support SATA, USB 3. 2 GEN1 signal, PCIE x2)
 1 SATA-600
 2 USB 3.2 GEN1 and 5 USB 2.0
1.2 Specifications
 CPU
 Intel® Alder Lake for LGA1700 Socket CPU (Max TDP at 65W).
 Chipset
 Intel® H610.
 BIOS
 AMI BIOS via SPI interface.
 System Memory
 Two 260-pin SO-DIMM sockets.
 Maximum up to 64GB DDR4 memory.
 Support 3200MHz.
 Onboard Multi I/O
 Four serial ports:
- COM1 in 9-pin D-Sub (on the rear I/O). Only COM1 supports RS-232/422/485.
- COM2~COM4 in 2x5-pin header (internal).
 USB Interface
 Two USB 3.2 GEN1 ports (on the rear I/O).
 Two USB 2.0 ports (on the rear I/O).
 Two USB 2.0 ports (internal).
 One 4-pin USB 2.0 wafer for Touch (internal).
 Ethernet
 LAN1: 2500/1000/100/10Mbps Gigabit/Fast Ethernet supports Wake-on-LAN, PXE
with Intel® i225V.
 LAN2: 1000/100/10Mbps Gigabit/Fast Ethernet supports Wake-on-LAN, PXE with
Intel® i219V.
 Serial ATA
 One SATA 3.0 port (6Gb/s).
 Audio
 Realtek Codec ALC897.
 Support line-out/MIC-in (on the rear I/O).
 Support Line-in/Line-out/Speaker in box header (internal).
 Display
 Intel® Integrated Graphics:
- Two HDMI1.4b connector, resolution up to 4096x2160 @24Hz.
- One VGA 2x8 pin wafer connector.

MANO561 Mini ITX Motherboard
Introduction 3
- One 24-bit dual channel LVDS and one 8-pin inverter connector. LVDS
resolution is max. up to 1920x1200. Default is LVDS
- One Embedded DisplayPort (eDP) with resolution max. up to 4096x2304
@60Hz; co-layout with LVDS.
 Expansion Interface
 One PCI-Express x16 slot.
 One PCI-Express Mini Card.
 One SIM card slot co-lay with miniPCIe and M.2 Key B socket. Default is M.2 Key B
socket.
 One M.2 Key B type 2242/3042/3052 includes PCIe x2, USB 3.2 GEN1 + SATA3.0,
PCIe + USB 3.2 GEN1 interfaces by BOM option. Default is USB 3.2 GEN1 +
SATA3.0.
 One M.2 Key E type 2230 with PCIe x1 and USB2.0.
 TPM
 Trusted Platform Module 2.0.
 Power Input
 One 12V~24V ATX 4-pin power input connector.
 One 12V~24V DC jack power input connector.
 Operating Temperature
 0°C ~ 60°C.
 Storage Temperature
 -10°C ~ 70°C.
 Form Factor
 Mini ITX (6.7” x 6.7”, 17.0cm x 17.0cm).
Note
All specifications and images are subject to change without notice.
1.3 Utilities Supported
 Chipset driver
 Graphics driver
 Intel ME driver
 Ethernet driver
 Audio driver
 Serial IO driver

MANO561 Mini ITX Motherboard
4 Introduction
1.4 Block Diagram

MANO561 Mini ITX Motherboard
Board and Pin Assignments 5
Section 2
Board and Pin Assignments
2.1 Board Layout
Top View

MANO561 Mini ITX Motherboard
6 Board and Pin Assignments
Bottom View

MANO561 Mini ITX Motherboard
Board and Pin Assignments 7
2.2 Rear I/O
Jumpers/Headers/Connectors
1 4-pin ATX Power Input Connector (CN18) 19 M.2 Key E Socket (CN22)
2 SIM Card Slot (CN25) 20 Audio Header (CN52)
3 Front Panel Header (CN8) 21 VGA Connector (CN5)
4 SATA Power Connector (CN13) 22 COM VDD Select Jumper (JP1)
5 SATA 3.0 Connector (CN7) 23 Digital I/O Connector (CN26)
6 COM4 serial Port (CN4) 24 USB 2.0 Header (CN15)
7 COM3 serial Port (CN3) 25 USB 2.0 4pin wafer (CN19)
8 COM2 serial Port (CN17) 26 DDR4 SO-DIMM Connectors (DIMM1,
DIMM2)
9 LVDS Signal Header (CN29) 27 SPI Header (CN81)
10 LVDS Backlight Control Header (CN55) 28 M.2 Key B Socket (SCN1)
11 eDP Connector (CN50) 29 DC Jack Power Connector (CN23)
12 AT/ATX Power Mode Select Jumper
(JP5) 30 USB 3.2 GEN1 Stack Port (CN10)
13 LVDS VDD Select Jumper (JP4) 31 USB 2 Stack Port (CN11)
14 System Fan Header (CN28) 32 LAN1(RJ-45) Connector (CN9)
15 CPU Fan Header (CN27) 33 LAN2(RJ-45) Connector (CN12)
16 Clear CMOS (JP3) 34 COM1 D-Sub Connector (CN1)
17 PCI-Express x16 Slot (CN20) 35 HDMI1.4 Connector (CN6)
18 PCI-Express Mini Card Connector (CN21) 36 Audio Jack (CN14)
Note
To identify the first pin of a header or jumper, please refer to the following
information:
 Usually, there is a thick line or a triangle near the header or jumper pin 1.
 Square pad, which you can find on the back of the motherboard, is usually
used for pin 1.

MANO561 Mini ITX Motherboard
8 Board and Pin Assignments
2.3 Jumper Settings
Jumper is a small component consisting of jumper clip and jumper pins. Install jumper clip on
2 jumper pins to close. And remove jumper clip from 2 jumper pins to open. The following
illustration shows how to set up jumper.
Before applying power to MANO561 Series, please make sure all the jumpers are in factory
default position. Below you can find a summary table of all jumpers and onboard default settings.
Note
Once the default jumper setting needs to be changed, please do it under power-
off condition.
2.3.1 COM1 Data/Power Select (JP1)
This is a 3x2-pin (pitch=2.00mm) jumper. The COM1 port has +5V power capability on
DCD and +12V on RI by setting JP1.
2.3.2 Clear CMOS (JP3)
This jumper allows you to clear the Real Time Clock (RTC) RAM in CMOS. You can clear
the CMOS memory of date, time, and system setup parameters by erasing the CMOS
Jumper Description Setting
JP1 COM Data/Power Select
Default: RS-232 Data
3-5 Close
4-6 Close
JP3 Clear CMOS
Default: Normal Operation 1-2 Close
JP4 LVDS VDD Select
Default: +3.3V Level 1-2 Close
JP5 AT/ATX Power Mode Select
Default: ATX Mode 1-2 Close
Function Setting
Power: Set COM1 pin 1 to +5V 1-3 close
Data: Set COM1 pin 1 to DCD (Default) 3-5 close
Power: Set COM1 pin 9 to +12V 2-4 close
Data: Set COM1 pin 9 to RI (Default) 4-6 close

MANO561 Mini ITX Motherboard
Board and Pin Assignments 9
RTC RAM data. The onboard button cell battery powers the RAM data in CMOS, which
includes system setup information such as system passwords.
To erase the RTC RAM:
1. Turn OFF the computer and unplug the power cord.
2. Remove the onboard battery.
3. Move the jumper clip from pins 1-2 (default) to pins 2-3. Keep the clip-on pins 2-3
for about 5~10 seconds, then move the clip back to pins 1-2.
4. Re-install the battery.
5. Plug the power cord and turn ON the computer.
6. Hold down the <Del> key during the boot process and enter BIOS setup to re-enter
data.
2.3.3 LVDS VDD Select (JP4)
The motherboard supports voltage selection for flat panel displays. Use this 2x3-pin
(pitch=2.0mm) jumper to set up VDD power of the LVDS connector. To prevent hardware
damage, before connecting please make sure that the input voltage of LVDS panel is
correct.
2.3.4 AT/ATX Power Mode Select (JP5)
This 3-pin (pitch=2.0mm) jumper allows you to select AT or ATX power mode.
Function Setting
Normal operation (Default) 1-2 close
Clear CMOS 2-3 close
Function Setting
+3.3V level (Default) 1-2 close
+5V level 2-4 close
+12V level 5-6 close
Function Setting
ATX mode (Default) 1-2 close
AT mode 2-3 close

MANO561 Mini ITX Motherboard
10 Board and Pin Assignments
2.4 Connectors
Signals go to other parts of the system through connectors. Loose or improper connection might
cause problems, please make sure all connectors are properly and firmly connected. Here is a
summary table showing connectors on the hardware.
Connector Description
CN1 COM1 D-Sub Connector
CN3~CN4 COM3~COM4 Headers
CN5 VGA Connector
CN6 HDMI1.4 Connector
CN7 SATA 3.0 Connector
CN8 Front Panel Header
CN10 USB 3.2 GEN1 Stack Port
CN11 USB 2.0 Header
CN9, CN12 LAN Connectors
CN13 SATA Power Connector
CN14 Audio Jack
CN15 USB 2.0 Header
CN17 COM2 Headers
CN18 ATX 4Pin Power Input Connector
CN19 USB 2.0 4pin wafer
CN20 PCI-Express x16 Slot
CN21 PCI-Express Mini Card Connector
CN22 M.2 Key E Socket
CN23 DC Jack Power Connector
CN24 SPI Header
CN25 SIM Card Slot
CN26 Digital I/O Connector
CN27, CN28 Fan Headers
CN29 LVDS Signal Header
CN50 eDP Connector
CN52 Audio Header
CN55 LVDS Backlight Control Header
SCN1 M.2 Key B Socket

MANO561 Mini ITX Motherboard
Board and Pin Assignments 11
2.4.1 COM1 D-Sub Connector (CN1)
The CN1 is a double 9-pin D-Sub connector for COM1 and COM2 serial port interfaces
on the rear I/O. Only COM1 supports RS-232/422/485 mode. The pin assignments of RS-
232/422/485 are listed in table below.
COM1:
COM1
Note
[*]: Pin 1 of COM1 can be DCD/+5V and pin 9 of COM1 can be RI/+12V by
selecting JP1 (see section 2.3.1).
2.4.2 COM2~COM4 Headers (CN17, CN3~CN4)
The motherboard comes with two 2x5-pin (pitch=2.00mm) headers for COM3~COM4
serial port interfaces.
Pin RS-232
(3T/5R)
RS-422
(1T/1R Full
Duplex)
RS-485
(1T/1R TX Enable
Low Active)
1 COM1C_DCD [*] TX (-) Data (-)
2 COM1C_RXD TX (+) Data (+)
3 COM1C_TXD RX (+) NC
4 COM1C_DTR RX (-) NC
5 GND GND GND
6 COM1C_DSR NC NC
7 COM1C_RTS NC NC
8 COM1C_CTS NC NC
9 COM1C_RI [*] NC NC
Pin Signal Pin Signal
1 DCD 2 DSR
3 RX 4 RTS
5 TX 6 CTS
7 DTR 8 RI
9 GND 10 NC

MANO561 Mini ITX Motherboard
12 Board and Pin Assignments
2.4.3 SATA 3.0 Connectors (CN7)
This connector supports the thin Serial ATA cable for primary internal storage device.
2.4.4 SATA Power Connector (CN13)
The CN51 is a 4-pin (pitch=2.54mm) connector for DC +12V and +5V power output.
2.4.5 USB 3.2 GEN1 Stack Port (CN10)
The motherboard comes with one stacked Universal Serial Bus (compliant with USB 3.2
GEN1) connector on the rear I/O for installing USB peripherals such as a keyboard,
mouse, scanner, etc.
Pin Signal
1 GND
2 TX+
3 TX-
4 GND
5 RX-
6 RX+
7 GND
Pin Signal
1 +5V
2 GND
3 GND
4 +12V
Pin Signal Pin Signal
1 USB_PWR 10 USB_PWR
2 USB#1_D- 11 USB#2_D-
3 USB#1_D+ 12 USB#2_D+
4 GND 13 GND
5 SSRX1- 14 SSRX2-
6 SSRX1+ 15 SSRX2+
7 GND 16 GND
8 SSTX1- 17 SSTX2-
9 SSTX1+ 18 SSTX2+

MANO561 Mini ITX Motherboard
Board and Pin Assignments 13
2.4.6 USB 2.0 Stack Port (CN15)
The motherboard comes with one stacked Universal Serial Bus (compliant with USB 2.0)
connector on the rear I/O for installing USB peripherals such as keyboard, mouse,
scanner, etc.
2.4.7 Ethernet Ports (CN9 and CN12)
The motherboard supports two Ethernet ports (CN11, CN19): two RJ45 connectors with
CN12: Intel® i225-V controller support 10/100/1000/2500Mbps.
CN9: Intel® i219-V controller support 10/100/1000 Mbps.
CN9 CN12
Note
CN9/CN12 supports Wake-on-LAN.
2.4.8 PCI-Express Mini Card Connector (CN21)
The CN21 complies with PCI-Express Mini Card Spec. V1.2.
Pin Signal Pin Signal
1 USB_PWR 2 USB_PWR
3 USB#5_D- 4 USB#6_D-
5 USB#5_D+ 6 USB#6_D+
7 GND 8 GND
Pin LAN Signal Pin LAN Signal
L1 Tx+ (Data transmission positive) L2 Tx- (Data transmission negative)
L3 Rx+ (Data reception positive) L4 RJ-1 (For 1000 Base-T only)
L5 RJ-1 (For 1000 Base-T only) L6 Rx- (Data reception negative)
L7 RJ-1 (For 1000 Base-T only) L8 RJ-1 (For 1000 Base-T only)
A Speed LED
LAN1: Intel® i219-V
OFF: 10Mbps data rate
Green: 100Mbps data rate
Orange: 1Gbps data rate
LAN2: Intel® i225-V
OFF: 10/100Mbps data rate
Green: 1Gbps data rate
Orange: 2.5Gbps data rate
B
Active LED(Yellow)
OFF: No link
Blinking: Link established; data
activity detected
Pin Signal Pin Signal
1 WAKE# 2 +3.3VAUX
3 NC 4 GND

MANO561 Mini ITX Motherboard
14 Board and Pin Assignments
5 NC 6 +1.5V
7 CLKREQ# 8 UIM_PWR/NC
9 GND 10 UIM_DAT/NC
11 REFCLK- 12 UIM_CLK/NC
13 REFCLK+ 14 UIM_REST/NC
15 GND 16 UIM_VPP/NC
17 NC 18 GND
19 NC 20 NC
21 GND 22 PERST#
23 PCIE_RX_D- 24 +3.3VAUX
25 PCIE_RX_D+ 26 GND
27 GND 28 +1.5V
29 GND 30 SMB_CLK
31 PCIE_TX_D- 32 SMB_DATA
33 PCIE_TX_D+ 34 GND
35 GND 36 USB_D-
37 GND 38 USB_D+
39 +3.3VAUX 40 GND
41 +3.3VAUX 42 NC
43 GND 44 NC
45 NC 46 NC
47 NC 48 +1.5V
49 NC 50 GND
51 NC 52 +3.3VAUX