BioCare Medical PATHCOM ONCORE PRO User manual

PathCom Systems Corporation
6400 Sierra Court, Suite E
Dublin, CA 94568
Document Number Form 751-02-03 Revision K4
2022-04-12 For In Vitro Diagnostic Use
Distributed
by: Biocare Medical
60 Berry Drive
Pacheco, CA 94553
Tel. [phone] | www.biocare.net | Fax: [phone]
ONCORE™ PRO
Operating Manual

ONCORE PRO, Operating Manual, Rev. K 2
Table of Contents
Section 1. Introduction .......................................................................................................................................... 7
Section 2. System Specifications ............................................................................................................................ 8
2.1. Instrument Overview .........................................................................................................................................8
2.2. Module Overview.............................................................................................................................................11
2.3. Technical Specifications ...................................................................................................................................12
2.4. Accessories Included with the Oncore Pro Slide Stainer .................................................................................13
2.5. Staining Area Range .........................................................................................................................................14
Slide Dimensions ................................................................................................................................................14
Tissue Thickness and Slide Placement ...............................................................................................................14
Section 3. Installation Requirements and Instructions ......................................................................................... 15
3.1. Installation Requirements................................................................................................................................15
3.2. Installation Instructions ...................................................................................................................................15
Contacts for Assistance ......................................................................................................................................16
Section 4. Instructions for Use ............................................................................................................................. 17
4.1. Starting Up the Slide Stainer............................................................................................................................17
4.2. Preparing and Printing Labels ..........................................................................................................................19
Add New Labels in the Barcode Editor...............................................................................................................19
Print Labels in the Slide Label Editor..................................................................................................................21
Move Slides to Printed Slides (for use with LIS only) .........................................................................................22
4.3. Loading Slides and Installing Chambers ...........................................................................................................22
Load/Unload Slides ............................................................................................................................................22
Install/Remove Chambers..................................................................................................................................23
4.4. Assigning Protocols: Scan Slides and Manually Assign Protocols ....................................................................24
4.5. Loading Reagents.............................................................................................................................................26
4.6. Reagent Vialing Specifications .........................................................................................................................27
7mL Reagent Vial Specifications.........................................................................................................................27
15mL Reagent Vial Specifications ......................................................................................................................27
Instructions for Use............................................................................................................................................28
4.7. Refill Buffer and Empty Waste .........................................................................................................................29
Refill the Wash Buffer Bottle .............................................................................................................................29
Empty the Waste Containers .............................................................................................................................29
4.8. Reagent Check: Scan Reagents ........................................................................................................................30
4.9. Starting the Run ...............................................................................................................................................33
Gantt Chart.........................................................................................................................................................35
4.10. Auto Start.......................................................................................................................................................36
4.11. Completing a Run...........................................................................................................................................36
Runtime Monitoring...........................................................................................................................................37
End of Run..........................................................................................................................................................38
Aborting a Run ...................................................................................................................................................39
4.12. Continuous Loading .......................................................................................................................................40
Stop the Current Run .........................................................................................................................................40
Restart the Run ..................................................................................................................................................41
4.13. Shutting Down the Slide Stainer ....................................................................................................................43
Section 5. System Utilities.................................................................................................................................... 44
5.1. Tools.................................................................................................................................................................44
Prepare Slides with Baking Slides Function........................................................................................................45
Load a Saved Slide Map File ...............................................................................................................................45
Verify the Calibration of SP1-Z1 or SP1-Z2.........................................................................................................45
Verify the Calibration of the Barcode Reader ....................................................................................................46

ONCORE PRO, Operating Manual, Rev. K 3
Clean Z1/Z2 Tubing ............................................................................................................................................46
(Optional) Access the Tubing Clean Log.............................................................................................................47
(Optional) Reset the Module/Chamber Usage Counter.....................................................................................47
Generate Reports...............................................................................................................................................48
Move Robot XYZZ Arm Aside .............................................................................................................................48
Perform System Initialization.............................................................................................................................48
Check for Module Malfunction ..........................................................................................................................48
Flush Tubing with Prime Pump Z1 and Z2 Function...........................................................................................49
Prime Pump Z1 or Pump Z2 ...............................................................................................................................49
Lock Door ...........................................................................................................................................................49
Unlock Door .......................................................................................................................................................49
Backup Report Data ...........................................................................................................................................50
5.2. Editors ..............................................................................................................................................................50
Editing Protocols in the Protocol Editor.............................................................................................................51
Restoring Protocol Customizations in the Protocol Editor.................................................................................53
Editing Protocols in the Protocol Editor: ISH/CISH/FISH ....................................................................................54
Viewing Special Protocols in the Protocol Editor...............................................................................................54
Changing the Protocol Template........................................................................................................................55
Importing Protocols in the PR Manager.............................................................................................................56
Assigning Negative Controls...............................................................................................................................58
Adding Reagents and Protocols in the Reagent Editor ......................................................................................59
Preparing RFID Reagent Tags with the RFID Tag Editor .....................................................................................61
Creating Custom Groups ....................................................................................................................................63
Creating Custom Panels .....................................................................................................................................64
5.3. Security ............................................................................................................................................................65
Change Password ...............................................................................................................................................65
User Administration ...........................................................................................................................................65
5.4. Settings ............................................................................................................................................................66
Baking Slide Settings ..........................................................................................................................................67
2D Barcode Format ............................................................................................................................................67
Save All Customizations .....................................................................................................................................69
Device Version....................................................................................................................................................69
Baking Slides Option...........................................................................................................................................69
Detect Waste Overflow Option..........................................................................................................................69
Run Without RFID Reader Option ......................................................................................................................69
Reagent Consumption Priority ...........................................................................................................................69
Language ............................................................................................................................................................69
Tubing Clean Tracking Option ............................................................................................................................70
Module Tracking Option ....................................................................................................................................70
5.5. Network ...........................................................................................................................................................71
5.6. LIS/LIMS ...........................................................................................................................................................73
Section 6. Reports................................................................................................................................................ 74
6.1. Generate a Report ...........................................................................................................................................74
Slide Barcode......................................................................................................................................................74
Patient Information............................................................................................................................................76
6.2. Report Types ....................................................................................................................................................77
Slide Report........................................................................................................................................................77
Reagent Usage in Run Report ............................................................................................................................79
Reagent Usage Report .......................................................................................................................................80
Slide Summary Report........................................................................................................................................81
Staining Runs......................................................................................................................................................82
6.3. Print and Save a Report ...................................................................................................................................83
6.4. Backup Report Data .........................................................................................................................................83

ONCORE PRO, Operating Manual, Rev. K 4
Section 7. System Maintenance ........................................................................................................................... 84
7.1. Daily Maintenance Recommendation .............................................................................................................84
Modules .............................................................................................................................................................84
Chamber.............................................................................................................................................................84
Tubing and Pumps..............................................................................................................................................84
7.2. Weekly Maintenance Recommendation .........................................................................................................85
Modules and Deck Plate.....................................................................................................................................85
Wash Station and Z1/Z2 Probes.........................................................................................................................85
Tubing and Pumps..............................................................................................................................................85
7.3. Monthly Maintenance Recommendation........................................................................................................86
Chambers ...........................................................................................................................................................86
Tubing ................................................................................................................................................................86
Robotic Arm .......................................................................................................................................................86
Computer ...........................................................................................................................................................86
7.4. Annual/Semi-Annual Maintenance..................................................................................................................86
Section 8. General Precautions ............................................................................................................................ 87

ONCORE PRO, Operating Manual, Rev. K 5
Oncore Pro Slide Stainer Information
Oncore Pro Slide Stainer Model: ONCPRO0001
Software Version: 3.0
Computer Configuration:
Laptop or Desktop Computer with Mouse
Instrument Communications Interface: USB 2.0
USB Cable has to be less than 3 meters (10 feet)
The use of this instrument is fully licensed under U.S. Patent no. 5,839,091; U.S. Patent no. 7,476,543; U.S.
Patent no. 7,635,453; and U.S. Patent no. 7,977,086 B2.
Oncore Pro Slide Stainer Software Product License
IMPORTANT: Please read the license carefully before using this Software. The right to use this Software is granted
only if the Customer agrees to the terms of this license
HOWEVER, USE OF THIS SOFTWARE INDICATES YOUR ACCEPTANCE OF THESE TERMS AND CONDITIONS.
In return for the payment of the applicable one time license fee included with the purchase price of the Oncore
Pro Slide Stainer, BioCare grants the user a license to use one copy of the Software subject to the following terms
and conditions. No title or ownership of the Software is conferred with this license.
1. The Software may be used on one Oncore Pro Slide Stainer.
2. The Software may not be copied.
3. The Software may not be disassembled, decompiled, decrypted or reverse engineered.
4. BioCare reserves the right to terminate this license upon breach. In the event of termination at BioCare’s
election, all copies of the Software must be returned to BioCare.
5. No title or ownership of the Software is conferred with this license.

ONCORE PRO, Operating Manual, Rev. K 6
Safety
Report any serious incidents related to this device to your local Oncore Pro representative and the state's
competent authority. Contact Customer Service if you have any questions or concern regarding safety.
Protection from High Temperatures
The instrument is equipped with a safety interlock system so that the door remains locked during instrument
operation. However, the heaters inside may reach high temperatures. Care must be exercised to make sure that
the heaters have cooled down sufficiently before removing the slides.
Protection from Moving Parts
The instrument is equipped with a safety interlock system so that the door remains locked during instrument
operation. The interlock will automatically engage to restrict access to the inside of the instrument while it is the
instrument is in operation. Never tamper with the safety interlock system.
Use of Hazardous Reagents
Some reagents used on the instrument may be considered hazardous. Hazardous reagent wastes must be
disposed of according to local, state and federal regulations. Wear appropriate Personal Protective Equipment to
prevent exposure. It is the responsibility of the user to comply with the local, state and federal regulations.
Maintenance
Do not attempt to service the Oncore Pro Slide Stainer unless instructed to do so by Technical Support. Doing so
will void the warranty. Removing the back panel may also electrical hazard.
The instrument must be unplugged from the power source before the outer housing can be removed. The power
supply is connected to 120/240V power source and the power cord must be disconnected from the AC power port
before any maintenance work is started.
Decontamination
Use bleach at 1:10 dilution to decontaminate the instrument. Do not use bleach with any other chemicals because
it may react and create toxic fumes. Decontaminate in a well ventilated room.

ONCORE PRO, Operating Manual, Rev. K 7
Section 1. Introduction
Intended Use of the Equipment
The Oncore Pro Slide Stainer is a fully-automated slide processing system for staining paraffin-embedded and
frozen tissue sections, cytospins, cell smears and fine needle aspirates. This universal system is designed to
automate the manual staining methods routinely used in immunohistochemistry, in situ hybridization and related
applications.
Quick Start-up
The Oncore Pro Service Team installs and tests each system to ensure optimal performance.
The system is factory-installed with a set of standard protocols optimized for use with the Oncore Pro detection
kits and its comprehensive line of ready-to-use primary antibodies and probes.
Flexible Programming
The Oncore Pro Slide Stainer software implements user-customized protocols and slide-specific programming. The
system provides intuitive programming routines, reagent and slide loading maps and a convenient run time
display. Each staining run can process 1 to 36 microscope slides. Each slide can be programmed to run a different
protocol.
Economic Use
The Oncore Pro Slide Stainer maximizes efficiency by operating with small volumes of reagent and wash buffer,
effectively reducing supply and waste disposal costs. The system provides the flexibility to optimize reagent
volumes and wash steps.
Reagent RFID Tags
Reagent RFID tags store programmable information such as reagent name, lot number and expiration date. The
on-board RFID reader scans and identifies reagent vials to automatically determine if there are sufficient resources
to complete a selected staining protocol.
Slide 2D Barcode Labels
The Oncore Pro Slide Stainer software provides a simple user interface to generate and print 2D Barcode labels for
slides. The on-board 2D barcode reader scans and identifies slides to automatically program a run and track slides.
All printed labels are heat and chemical-resistant, allowing users to apply slide labels prior to starting the staining
procedure.

ONCORE PRO, Operating Manual, Rev. K 8
Section 2. System Specifications
The Oncore Pro Slide Stainer system employs a unique integration of hardware, software, and reagent chemistry
to provide full automation of immunohistochemical staining methods. This section provides an overview of the
instrument and details the technical specifications.
2.1. Instrument Overview
Figure 1
1. Slide Deck holds 36 modules, a reagent rack, and 2 probe wash stations.
2. X axis mechanism moves the robotic arm from left to right.
3. Y axis mechanism carries the Z head assembly and moves the arm from front to back
4. Z head Assembly consists of 2 independent Z axes (Z1 and Z2) situated on the Y arm.
5. Power Button turns the instrument on/off.
6. Door controls access to the instrument.
7. Linear Solenoid locks the door.
8. Safety Interlock Switch blocks unsafe access to the instrument while the robotic arm is in motion.
9. Liquid Level Sensor (Z1 only) detects the liquid level in the reagent vial and waste station during runtime.
The system will issue a warning when a reagent vial has insufficient volume or when a waste station is
overflowing.

ONCORE PRO, Operating Manual, Rev. K 9
Figure 2
1. 2D Barcode Reader scans the labelled slides on the slide deck to assign protocols for the staining run.
2. RFID Reader scans the RFID-tagged reagent vials to determine the reagents’ positions on the rack and
updates the reagent usage information to the RFID tags during the run.
3. Reagent Rack holds the reagent vials. There are 40 available reagent vials positions.
4. Reagent Vials holds the reagents. 15mL and 7mL size options.
5. Pumps (Z1 and Z2) draw and dispense buffer and reagents through the in-line tubing (max 5mL capacity)
6. Wash/Waste Station is an assembly located in the rear left corner of the instrument and is used as a
cleaning station for the reagent probes. There is a purging position for the reagent waste and a
percolating position for cleaning the outside of the probe each time a new reagent is used.
7. Hazardous Wash/Waste Station is a second probe wash station dedicated to hazardous reagents.
Hazardous reagents will be separately dispensed into the hazardous waste station and will be collected in
the Hazardous Waste Container.
8. Z1 Probe is a Teflon™-coated stainless steel probe that aspirates the reagents from the vials/in-line wash
buffer and dispenses the reagents into the chambers.
9. Z2 probe is a Teflon™-coated stainless steel probe that extracts the reagent waste from the chambers and
aspirates/dispenses reagent during on-board mixing.
10. Module is an assembly that holds 1 glass slide. 36 modules per instrument.
Not pictured:
11. Tubing (Z1 and Z2) connects the pumps with the probes to transfer buffer, reagents, and waste.

ONCORE PRO, Operating Manual, Rev. K 10
Figure 3
1. Feet adjusted to level the instrument on the work surface.
2. Main Power Supply connects to the wall outlet and provides power to the instrument.
3. Power Supply Switch turns the power supply on/off.
4. AC Power Port is the position to plug in the power cord.
5. Fan provides cooling to the instrument and its electrical components.
6. USB Port is the position to plug in the USB cable.
7. U-Ring is the position to attach an anti-theft chain to the computer.
8. Waste Tubing (Blue) connects the waste station to the waste container to transfer waste (gravity-fed).
9. Hazardous Waste Tubing (Black) connects the waste station to the hazardous waste container to transfer
hazardous waste (gravity-fed).

ONCORE PRO, Operating Manual, Rev. K 11
2.2. Module Overview
Figure 4
1. Side Retainer Clips (2) secure the module onto the
instrument deck plate.
2. LED Light displays heater status green (inactive) or
orange (active).
3. Hinge secures the slide at the back.
4. Chamber Chimney reagent dispensation/waste
extraction point.
5. Slip Holder holds the chamber. Moves to controlled
angles to facilitate incubation and reagent
dispensation/waste extraction.
6. Chamber (consumable) holds reagent/buffer on the
slide during the incubation and washes.
7. Side Rails (2) secure the slide on the left/right.
8. Heater maintains temperature during incubation.
9. Slide Clip secures the slide at the front.
Not pictured:
10. Glass Slide is a standard microscope slide to which
specimen(s) are mounted for processing on the
instrument. Standard slide dimensions are 25mm x
75mm x 1mm.

ONCORE PRO, Operating Manual, Rev. K 12
2.3. Technical Specifications
Dimensions W x H x D
36.5in x 22in x 24in/93cm x 56cm x 61cm
(with door closed)
36.5in x 36in x 24in/93cm x 91cm x 61cm
(with door open)
Weight
125lb (57kg)
Electrical requirements
120V 110/120V (±10%) 60Hz (±2Hz) 850 watts
220V 220/240V (±10%) 50Hz (±2Hz) 850 watts
Mains Connection: IEC320
Normal operating temperature
18°C-26°C (64°F-79°F)
Slide capacity
1 - 36 glass slides
Reagent capacity
40 different reagents (15 mL/7mL reagent vial)
Heating capacity Waste Separation
Room temperature to 103°C. Maximum 110°C.
Reagent dispense volumes
130uL standard test volume
(65 minimum-400 µl maximum)
1 hazardous waste, 1 non-hazardous waste
Reagent probe volume capacity
20 µL minimum-4500µL maximum
Computer controller requirements
BioCare reserves the right to change the computer controller specifications at any time.
Intel Core i5-2410M CPU 2.3GHz
4GB RAM
500GB Hard drive
4 USB 2.0 communication ports
Computer/Monitor
Laptop or Desktop Computer
Operating System
Windows 7, 10
Printer
Zebra TLP 3844-Z, Zebra GX430t or Zebra ZD620t
Surge Protector
120/240 VAC, 15 Amps, 50/60 Hz
LIS Connectivity
Compatible with SQL Database and HL7 messaging standards.
Operating Logic
Designed to calculate the most time-efficient sequence of steps to complete a programmed staining run.
Protocol Logic
Protocols are generated from a common protocol template optimized for each detection system.
End-users have the limited ability to customize key protocol steps.
Advanced users have full flexibility to add/remove and customize each step in the protocol template and to
generate special protocols.

ONCORE PRO, Operating Manual, Rev. K 13
2.4. Accessories Included with the Oncore Pro Slide Stainer
Reagent Rack Two removable reagent racks. Each reagent rack holds a maximum of 40 reagent vials.
Removable Vial Holder Installed on the reagent rack for programming RFID-tagged reagent vials.
Buffer Container 2L plastic bottle with quick disconnect fittings. Stores the in-line wash buffer.
Waste Container Set of two 4L plastic bottles with cap. Stores the reagent waste generated during the run.
Label Printer 2D barcode printer, thermal-transfer.
Labels Size 19.05mm (0.75in) x 25.4mm (1in), 1000 labels/roll.
Ribbon Media ribbon for the printer.
USB Cable Connects the instrument and computer.
Power Cord, Instrument
Computer Pre-configured for use with instrument.
Computer Mouse
Lint-Free Alcohol Wipes
Chamber Set of 36 pre-installed on the modules.

ONCORE PRO, Operating Manual, Rev. K 14
2.5. Staining Area Range
To ensure staining quality and reliability, slides should be prepared following the guidelines of the Oncore Pro
system.
Slide Dimensions
Standard slide dimensions are 25mm x 75mm x 1mm
Material Glass, ISO 8037/1
Note: Use of non-standard slides may affect staining area and staining quality.
Tissue Thickness and Slide Placement
The recommended tissue thickness is 2-5 microns.
The circled area is the recommended tissue placement area.
The yellow highlighted region is the staining area range. This range may be expanded to the blue highlighted
regions; however, staining results may not be ideal in these areas.
Figure 5
The IHC staining area extends to the 40 mm line on the slide.
The ISH staining area extends to the 30 mm line on the slide.
Dimensions (mm)
Width
25–26.0 mm (0.98–1.02 in)
Length
74.75–75.5 mm (2.94–2.97 in)
Thickness
0.95–1.1 mm (0.038–0.043 in)

ONCORE PRO, Operating Manual, Rev. K 15
Section 3. Installation Requirements and Instructions
This section provides an overview of the installation of the Oncore Pro Slide Stainer to be performed by the field
service engineer. The following requirements should be met to ensure proper instrument function.
3.1. Installation Requirements
Location Place the system in an area where it is easy to operate and easy to connect to the instrument.
Surface Prior to unpacking, ensure that the work area for the instrument is a solid, level surface that can safely
support the weight of the system.
Size Minimum dimensions for the work area are 36.5 inch (93 cm) width x 36 inch (91 cm) height x 24 inch (61 cm)
depth clearance.
Environment The work area must be in an environment with an ambient temperature between 18°C-26°C (64°F-
79°F). The area must be properly ventilated with a maximum relative humidity of 80% for temperatures up to
31oC; Pollution Degree II or less. The equipment will produce less than 85 decibels at peak operation.
Power source The instrument and computer must be connected to a 120V/240 15A supply with grounding (3
prong). It is recommended to use a dedicated power source to prevent interference from other instruments or
equipment. It is also recommended to use a UPS (uninterruptible power supply) with minimum 1500VA. This will
help to prevent unexpected system failures due to an unstable power grid system or in the event of a temporary
power outage.
3.2. Installation Instructions
Unpacking The system is packaged in a wooden crate mounted on a pallet. Unlatch all fasteners and remove the
lid on top of the crate first. Remove the computer, accessories box and label printer from the shelf inside the
crate. Remove the shelf and the sides of the crate.
Installation Requires 2 people. Each person should pick up one end of the instrument and carefully lift it out of
the crate. Carefully move the instrument to the operating area and place it on the bench. Level the instrument
surface using a bubble level. Remove all packing material and the packaging securing the robotic arm. Verify that
all axes can move freely before operating the instrument. Unpack and install the computer and accessories.
Hooking up Connect the USB cable from the designated port on the computer to the back of the instrument.
Do not plug and unplug the USB cable while the PC or Instrument is on.
***Always turn off the instrument and PC before plugging and unplugging the USB cable.
Connect the Computer to the power source or UPS. Follow the instructions on the UPS, as some may require
powering up for several hours to charge the internal battery. Using a standard IEC320 compatible power cord,
connect the AC power port at the rear of the instrument to the power source or UPS.
Cut the waste tubing to size and route to the waste bottles on the floor. The ideal configuration is straight down to
the waste bottle in order to minimize the chance of overflow and waste buildup.
Avoid immersing the waste tubing in the waste bottle or flattening and kinking the tubing as this
may disrupt the gravity fed drainage and result in waste overflow.

ONCORE PRO, Operating Manual, Rev. K 16
Starting up Turn on the instrument and computer.
Power on the power supply switch on the back of the instrument.
Power on the Slide Stainer by pushing on the power button at the front of the instrument.
Log in to the computer with the default User Name: PathCom and Password: 6747l
Note: The user may change the computer user name and password after initial log in.
Disable the Wi-Fi radio and local internet connection (if applicable).
This feature may cause unexpected crashes during instrument operation.
The internet access should only be enabled for a remote support session, email communication or
web conference call. Disable the internet access while the instrument is in operation to prevent
unexpected crashes.
Disable automatic time synchronization.
This feature may cause unexpected crashes during instrument operation.
Figure 6
For Windows 7 systems: Configure Internet Time Settings
within Windows Date and Time.
Uncheck the box, Synchronize with an Internet time server.
For Windows 10 systems: Configure Time & Language settings
within Windows Settings.
Toggle Off the Date and time options as shown.
Figure 7
Load the ribbon and media on the barcode label printer according to the manufacturer’s instructions.
Connect the printer to the designated port on the computer and switch the power on.
The printer driver will automatically install within a few minutes.
Calibrate the media if needed using the Zebra Setup Utilities.
The on-site field service engineer will perform the necessary system checks on robot, modules, and pumps.
Contacts for Assistance
Customer Service: 925-603-8000
Technical Support: 800-542-2002
Replacement of Consumable Materials
Replacements for all consumable materials can be obtained from:
Website: www. biocare.net

ONCORE PRO, Operating Manual, Rev. K 17
Section 4. Instructions for Use
This section provides the instructions for daily routine operation of the Oncore Pro Slide Stainer.
Please check all Requirements p.7 before beginning instrument operation.
4.1. Starting Up the Slide Stainer
Turn on the Slide Stainer using the power button and then turn on the computer.
Note: It is important to follow this exact power on sequence.
Double-click the shortcut for the Oncore Pro Slide Stainer UI to access the login screen.
Select “Yes” when prompted by Windows User Account Control to grant access permissions.
Login to the main user interface.
Default User ID: Supervisor
Password: Supervisor
Figure 8
Refer to Security, p. 65, for information on managing User IDs and Passwords.
Close the door of the Slide Stainer and click “Enter”to access the Main screen and begin system initialization.
The system will take a few minutes to verify all connections between the instrument and the computer, and then
home the robotic arm, modules, and pumps.
Figure 9
Tip: If the system fails to start or is stopped/interrupted while performing a task, re-initialize the system and try
again. Refer to Perform System Initialization, p.48, for more information.

ONCORE PRO, Operating Manual, Rev. K 18
An interactive slide map corresponding to the 36 slide positions is displayed on the Main screen, displaying the
status of the modules.
Figure 10
All routine functions are readily accessed from the Main screen.
To perform a typical run, click:
Prepare Labels to print labels for slides. Each label is printed with a 2D barcode required to identify the slide.
Load/Unload Slides to lift and lower lids for inserting and removing slides.
Auto Start to automatically start the run after loading the labeled slides and tagged reagents.
Scan Slides to scan the barcode labels on the slides.
Assign Protocols to manually assign a protocol to a slide.
Scan Reagents to scan the RFID tags on the reagent vials.
System Utilities to access additional features and utility functions.
Clean Screen to clear the slide map.
Exit to close the application.

ONCORE PRO, Operating Manual, Rev. K 19
4.2. Preparing and Printing Labels
From the Main screen, click “Prepare Labels”to open the Slide Label Editor:
Figure 11
Labels available for printing are listed on the screen under New Slides.
A. Select New Slides to create or view new labels.
B. Select Printed Slides to review or reprint a label.
C. Select Scanned Slides to review labels that have already been scanned.
D. Select Processed Slides to review labels that have already been processed.
Add New Labels in the Barcode Editor
Labels must be prepared in the Barcode Editor and added to the Slide Label Editor before they can be printed.
To add new labels, click “Add” to open the Barcode Editor.
Enter the Patient ID, Case Number, and other required label information* into the designated fields.
Note: caret ^and tilde ~characters are not permitted in the entry fields.
(Optional) Select the Date Time of the label.
(Optional) Select the name of the Doctor from the
dropdown list. To add new names to the list, refer to
2D Barcode Format p. 67.
(Optional)* To print the “Block ID” field to the slide
label, the user must change the default label format.
Select “Container Identifier” from the drop-down list
in the desired field of the Label Formatter.
Note: The information entered may not be printable
due to the size constraints of the label. Use
abbreviations as needed or select a different label
format. Protocol Name, Patient ID, Date, Case
Number, Hospital Name and Description are printed
on the label by default. To change this setting, refer
to 2D Barcode Format p.67.
Figure 12
Next, add protocols to the list of Selected Protocols:

ONCORE PRO, Operating Manual, Rev. K 20
To add protocols to the Selected Protocols, select protocol(s) from the list of Available Protocols and click “Add”.
Tip: The user may search the list of protocols by typing the first few letters of the protocol name. Click “Save” to
generate new labels for each protocol in the list of Selected Protocols.
Alternatively, the user may use a customized sublist
of available protocols by selecting a custom group
from the Custom Group dropdown list.
Figure 13
Refer to Creating Custom Groups, p. 62, for more
information on creating custom groups.
Figure 14
To remove protocols from the list of Selected Protocols, select protocol(s) from the list and click “Remove”.
(Optional) To add a positive and/or negative control to the Selected Protocols, select the protocol and check the
boxes Add With: Positive and/or Negative, and click “Add”. Click “Save” to generate new labels.
Refer to Assigning Negative Controls, p. 58, for more
information on assigning negative controls to
protocols.
Figure 15
Figure 16