Bruker NMR CryoFIT User manual

CryoFIT
CryoProbe Flow Conversion System
Installation Manual
Version 003
Innovation with Integrity
●
NMR

Copyright © by Bruker Corporation
All rights reserved. No part of this publication may be reproduced, stored in a retrieval
system, or transmitted, in any form, or by any means without the prior consent of the
publisher. Product names used are trademarks or registered trademarks of their re-
spective holders.
This manual was written by
T. Marquardsen, J. Ganz
© August 14, 2015 Bruker Corporation
P/N: H12214
For further technical assistance for this product, please do not hesitate to contact your
nearest BRUKER dealer or contact us directly at:
Bruker Corporation
Am Silberstreifen
76287 Rheinstetten
Germany
Phone: + 49 721 5161 6155
E-mail: [email protected]
Internet: www.bruker.com

Contents
H12214_1_003 3
Contents
1 About This Manual .............................................................................................................................5
1.1 Policy Statement .................................................................................................................5
1.2 Symbols and Conventions ..................................................................................................5
2 Introduction.........................................................................................................................................7
3 Transport, Packaging and Storage ...................................................................................................9
3.1 Symbols on the Packaging .................................................................................................9
3.2 Inspection at Delivery........................................................................................................10
3.3 Packaging .........................................................................................................................11
3.4 Storage .............................................................................................................................11
4 Flow Hardware ..................................................................................................................................13
4.1 CryoFIT Accessory (PZ H13485)......................................................................................14
5 Installation.........................................................................................................................................15
5.1 Installation with a Warm CryoProbe..................................................................................15
5.2 Installation with a Cold CryoProbe....................................................................................16
5.3 Assembling the CryoFIT Accessory..................................................................................16
6 Inserting the Flow Cell .....................................................................................................................19
7 Removing the Flow Cell ...................................................................................................................29
8 Dismantling and Disposal................................................................................................................33
8.1 Dismantling .......................................................................................................................33
8.2 Disposal ............................................................................................................................33
9 Contact ..............................................................................................................................................35
List of Figures...................................................................................................................................37

Contents
4 H12214_1_003

About This Manual
H12214_1_003 5
1 About This Manual
This manual enables safe and efficient handling of the device.
This manual is an integral part of the device, and must be kept in close proximity to the
device where it is permanently accessible to personnel. In addition, instructions concerning
labor protection laws, operator regulations tools and supplies must be available and adhered
to.
Before starting any work, personnel must read the manual thoroughly and understand
its contents. Compliance with all specified safety and operating instructions, as well as local
work safety regulations, are vital to ensure safe operation.
The figures shown in this manual are designed to be general and informative and may not
represent the specific Bruker model, component or software/firmware version you are
working with. Options and accessories may or may not be illustrated in each figure.
1.1 Policy Statement
It is the policy of Bruker to improve products as new techniques and components become
available. Bruker reserves the right to change specifications at any time.
Every effort has been made to avoid errors in text and figure presentation in this publication.
In order to produce useful and appropriate documentation, we welcome your comments on
this publication. Support engineers are advised to regularly check with Bruker for updated
information.
Bruker is committed to providing customers with inventive, high quality products and services
that are environmentally sound.
1.2 Symbols and Conventions
Safety instructions in this manual are marked with symbols. The safety instructions are
introduced using indicative words which express the extent of the hazard.
In order to avoid accidents, personal injury or damage to property, always observe safety
instructions and proceed with care.
DANGER
DANGER indicates a hazardous situation which, if not avoided, will result in
death or serious injury.
This is the consequence of not following the warning.
1. This is the safety condition.
uThis is the safety instruction.

About This Manual
6 H12214_1_003
WARNING
WARNING indicates a hazardous situation, which, if not avoided, could result
in death or serious injury.
This is the consequence of not following the warning.
1. This is the safety condition.
uThis is the safety instruction.
CAUTION
CAUTION indicates a hazardous situation, which, if not avoided, may result in
minor or moderate injury or severe material or property damage.
This is the consequence of not following the warning.
1. This is the safety condition.
uThis is the safety instruction.
NOTICE
NOTICE indicates a property damage message.
This is the consequence of not following the notice.
1. This is a safety condition.
uThis is a safety instruction.
SAFETY INSTRUCTIONS
SAFETY INSTRUCTIONS are used for control flow and shutdowns in the event
of an error or emergency.
This is the consequence of not following the safety instructions.
1. This is a safety condition.
uThis is a safety instruction.
This symbol highlights useful tips and recommendations as well as
information designed to ensure efficient and smooth operation.

Introduction
H12214_1_003 7
2 Introduction
This document describes the installation of the CryoFITTM accessory, including the insertion
and removal of the flow cell.
Important Information
NOTICE
Risk of Material Damage Due to Improper Usage
Failure to observe the following safety warnings may result in material damage.
uNever try to spin the flow cell.
uNever use the sample lift if the flow cell is installed.
uDo not try to insert NMR sample tubes.
uDo not use the sample changer.
uDo not use the device with a BCU05 (freezing).
uMake sure the sample changer is not used during the flow application.

Introduction
8 H12214_1_003

Transport, Packaging and Storage
H12214_1_003 9
3 Transport, Packaging and
Storage
Retrofitting, repairs, adjustments or dismantling of the device must only be carried out by
Bruker Service or personnel authorized by Bruker. Damage due to servicing that is not
authorized by Bruker is not covered by your warranty.
3.1 Symbols on the Packaging
The following symbols are affixed to the packaging material. Always observe the symbols
during transport and handling.
Top The arrow tips on the sign mark the top of the
package. They must always point upwards;
otherwise the content may be damaged.
Fragile Marks packages with fragile or sensitive
contents.
Handle the package with care; do not allow the
package to fall and do not allow it to be
impacted.
Protect Against Moisture Protect packages against moisture and keep
dry.
Attach Here Lifting gear (lifting chain, lifting strap) must
only be attached to points bearing this symbol.
Center of Gravity Marks the center of gravity of packages.
Note the location of the center of gravity when
lifting and transporting.
Weight, Attached Load Indicates the weight of packages.
Handle the marked package in accordance
with its weight.
Permitted Stacking Load Indicates packages which are partially
stackable.
Do not exceed the maximum load-bearing
capacity specified on the symbol in order to
avoid damaging or destroying the content.

Transport, Packaging and Storage
10 H12214_1_003
Do not Damage Air-tight
Packaging
The packaging is air-tight. Damage to the
barrier layer may render the contents
unusable.
Do not pierce.
Do not use sharp objects to open.
Component Sensitive to
Electrostatic Discharge
The packaging contains components which
are sensitive to an electrostatic discharge.
Only allow packaging to be opened by trained
personnel.
Establish potential equalization before
opening.
Protect from Heat Protect packages against heat and direct
sunlight.
Protect from Heat and
Radioactive Sources
Protect packages against heat, direct sunlight
and radioactive sources.
Table3.1: Symbols on the Packaging
3.2 Inspection at Delivery
Upon receipt, immediately inspect the delivery for completeness and transport damage.
Proceed as follows in the event of externally apparent transport damage:
• Do not accept the delivery, or only accept it subject to reservation.
• Note the extent of the damage on the transport documentation or the shipper's delivery
note.
• Initiate complaint procedures.
Note:
Issue a complaint in respect to each defect immediately following detection. Damage
compensation claims can only be asserted within the applicable complaint deadlines.