Capintec CRC-25R User manual

CRC®-25R
Manual Stock No. 9250-0122 Rev. H – March 2015
OWNER’S MANUAL
Capintec, Inc.
Sales and Marketing
and Customer Support
6 Arrow Road
Ramsey, NJ 07446
Phone (800) ASK-4CRC
Fax [phone]
Capintec, Inc.
Only Authorized Service Center
620 Alpha Drive
Pittsburgh, PA 15238
Phone [phone]
Fax [phone]
Copyright©2006 Capintec, Inc.
®CRC is a registered trademark of Capintec, Inc.
ALL RIGHTS RESERVED
An Eczacɩbaşɩ-Monrol company

CAPINTEC, INC. CRC®-25R
TABLE OF CONTENTS
PREFACE
SAFETY.............................................................................................................................1-1
SYMBOL DEFINITIONS ................................................................................................. 1-1
WARNING AND CAUTION LABELS...............................................................................1-2
CAUTIONS AND NOTES................................................................................................1-3
GENERAL SAFETY TIPS...............................................................................................1-6
FUNCTIONAL & TECHNICAL DESCRIPTION..................................................................2-1
INTENDED USE.............................................................................................................2-1
OPERATOR PROFILE....................................................................................................2-1
OPERATOR TRAINING..................................................................................................2-1
FUNCTIONAL DESCRIPTION........................................................................................ 2-2
OVERALL PROGRAM FLOW......................................................................................... 2-3
Utility Programs...........................................................................................................2-3
Test Programs.............................................................................................................2-3
TECHNICAL DESCRIPTION .......................................................................................... 2-4
On / Off Switch............................................................................................................2-4
Warm Up Period..........................................................................................................2-4
Environment Requirements.........................................................................................2-4
Operational.............................................................................................................2-4
Storage...................................................................................................................2-4
Power Requirements...................................................................................................2-5
Line Voltage............................................................................................................2-5
Line Filter................................................................................................................2-5
Ground Current.......................................................................................................2-5
Power Connector and Cable...................................................................................2-5
Dimensions .................................................................................................................2-6
Console ..................................................................................................................2-6
Chamber.................................................................................................................2-6
Cables ....................................................................................................................2-6
Performance................................................................................................................2-6
Regulatory Listings......................................................................................................2-7
EMC .......................................................................................................................2-7
Electrical.................................................................................................................2-7
ETL Listed ..............................................................................................................2-7
GENERAL OPERATING INSTRUCTIONS ........................................................................3-1
GENERAL.......................................................................................................................3-1
KEYBOARD....................................................................................................................3-1
Layout.........................................................................................................................3-1
Key Usage...................................................................................................................3-2
NUCLIDE Keys.......................................................................................................3-2
USER Keys.............................................................................................................3-2
March 15 TABLE OF CONTENTS TOC - 1

CAPINTEC, INC. CRC®-25R
SOURCES Key .......................................................................................................3-2
NUCL Key ...............................................................................................................3-2
CAL# Key................................................................................................................3-2
TIME Key ................................................................................................................3-2
TEST Key................................................................................................................3-2
BKG Key .................................................................................................................3-2
HOME Key ..............................................................................................................3-3
MENU Key ..............................................................................................................3-3
Ci / Bq Key ..............................................................................................................3-3
CE Key....................................................................................................................3-3
ENTER (PRINT) Key...............................................................................................3-3
NUMBER / LETTER (Alphanumeric) Keys ..............................................................3-3
ARROW Keys (and )........................................................................................3-3
ENTERING DATA ...........................................................................................................3-4
Numeric Data...............................................................................................................3-4
Alphanumeric Data ......................................................................................................3-4
MAKING MENU SELECTIONS .......................................................................................3-4
RESPONDING TO QUESTIONS (YES) or (NO)..............................................................3-4
SYSTEM SETUP ................................................................................................................4-1
GENERAL.......................................................................................................................4-1
RECEIVING CONDITION EXAMINATION.......................................................................4-1
UNPACKING AND INSTALLATION.................................................................................4-1
ASSEMBLY.....................................................................................................................4-2
Liners, Dippers, Optional Dipper and Holders ..............................................................4-4
ENVIRONMENT REQUIREMENTS.................................................................................4-5
POWER REQUIREMENTS .............................................................................................4-5
Readout.......................................................................................................................4-5
Printers (optional).........................................................................................................4-5
TURN ON PROCEDURES..............................................................................................4-6
GENERAL OPERATIONAL SETUP ................................................................................4-6
ACCEPTANCE TESTING................................................................................................4-8
Chamber Tests ............................................................................................................4-8
Diagnostics Test......................................................................................................4-8
Daily Test ................................................................................................................4-8
Accuracy Test..........................................................................................................4-8
OPERATIONAL SUMMARY............................................................................................4-8
SYSTEM INITIALIZATION..................................................................................................5-1
GENERAL.......................................................................................................................5-1
SETTING DATE AND TIME ............................................................................................5-1
CHOOSING Ci or Bq.......................................................................................................5-3
PRINTING.......................................................................................................................5-4
Printer Power Requirements........................................................................................5-4
Printer Selection...........................................................................................................5-5
RS-232....................................................................................................................5-6
USB.......................................................................................................................5-16
NONE....................................................................................................................5-17
SCREEN SETUP...........................................................................................................5-17
TOC - 2 TABLE OF CONTENTS March 15

CAPINTEC, INC. CRC®-25R
Screen Saver ............................................................................................................5-18
Screen Contrast ........................................................................................................5-19
CHAMBER INITIALIZATION .............................................................................................6-1
GENERAL.......................................................................................................................6-1
USER KEY ASSIGNMENT ............................................................................................. 6-1
Selecting User Key......................................................................................................6-2
Current Assignment Display........................................................................................6-2
Nuclide Name Assignment..........................................................................................6-3
Assignment Confirmation ............................................................................................6-3
TEST SOURCES............................................................................................................ 6-3
Source Verification......................................................................................................6-5
Entering Serial Number...............................................................................................6-6
Entering Calibration Date ............................................................................................6-6
Entering Calibration Activity.........................................................................................6-7
Indicating Daily Usage................................................................................................. 6-8
Confirming Calibration Data ........................................................................................6-8
CONSTANCY TEST SOURCE....................................................................................... 6-8
No Daily Source Chosen.............................................................................................6-8
One Daily Source Chosen...........................................................................................6-9
More than One Daily Source Chosen..........................................................................6-9
MOLY ASSAY SETUP.................................................................................................. 6-10
Selecting Moly Assay Method.................................................................................... 6-11
Moly Assay Limit .......................................................................................................6-13
ADDING A NUCLIDE.................................................................................................... 6-14
Entering Nuclide Name..............................................................................................6-14
Entering Half-Life.......................................................................................................6-15
Entering Calibration Numbers....................................................................................6-16
Determining Calibration Numbers......................................................................... 6-16
DELETING A NUCLIDE................................................................................................ 6-17
CALIBRATION NUMBERS ........................................................................................... 6-18
Entering New Calibration Numbers............................................................................6-19
Changing Calibration Numbers..................................................................................6-21
Restoring Original Calibration Numbers ....................................................................6-22
LINEARITY TEST DEFINITION.................................................................................... 6-23
Setting Up Standard Linearity Test............................................................................ 6-24
Setting Up Lineator Test............................................................................................6-25
Setting Up Calicheck Test .........................................................................................6-27
REMOTE NUCLIDE ASSIGNMENT (LEGACY SYSTEMS ONLY) ............................... 6-28
Remove Nuclides......................................................................................................6-29
Adding Nuclides ........................................................................................................6-30
USB PORT SETTINGS................................................................................................. 6-30
ACCEPTANCE & QUALITY ASSURANCE TESTS........................................................... 7-1
GENERAL.......................................................................................................................7-1
ACCEPTANCE TESTS...................................................................................................7-1
Diagnostic Test ...........................................................................................................7-1
Daily Test....................................................................................................................7-1
Accuracy Test .............................................................................................................7-2
March 15 TABLE OF CONTENTS TOC - 3

CAPINTEC, INC. CRC®-25R
Linearity Test ...............................................................................................................7-2
DAILY QUALITY ASSURANCE TESTS ..........................................................................7-2
Daily Tests...................................................................................................................7-2
Accuracy Test..............................................................................................................7-2
Contamination Test......................................................................................................7-3
QUARTERLY TESTS......................................................................................................7-4
Diagnostic Test............................................................................................................7-4
YEARLY TESTS..............................................................................................................7-4
Linearity Test ...............................................................................................................7-4
BACKGROUND AND TESTS.............................................................................................8-1
GENERAL.......................................................................................................................8-1
BACKGROUND...............................................................................................................8-1
DAILY TEST....................................................................................................................8-3
Auto Zero.....................................................................................................................8-3
Background..................................................................................................................8-4
Chamber Voltage.........................................................................................................8-6
Data Check..................................................................................................................8-7
Accuracy and Constancy Test in Daily Test.................................................................8-7
CHAMBER VOLTS..........................................................................................................8-9
ACCURACY TEST ........................................................................................................8-10
DIAGNOSTICS...................................................................................................................9-1
GENERAL.......................................................................................................................9-1
MEASUREMENT PROCEDURES....................................................................................10-1
GENERAL.....................................................................................................................10-1
MEASUREMENT PROCEDURES.................................................................................10-2
General Activity Measurement Procedure..................................................................10-2
Optimizing Low Activity Measurements......................................................................10-2
Specifying Nuclide .....................................................................................................10-2
Pre-Set Nuclide key:..............................................................................................10-2
User Key: ..............................................................................................................10-3
NUCL Key: ............................................................................................................10-3
Entering Calibration Number......................................................................................10-4
SOURCES Key..........................................................................................................10-5
Selecting Resolution..................................................................................................10-5
ACTIVITY AT A DIFFERENT TIME...............................................................................10-6
USER ID........................................................................................................................10-8
PRINTING A RECORD OF THE MEASUREMENT .......................................................10-9
OKIDATA Printer........................................................................................................10-9
Ticket Chosen: ......................................................................................................10-9
Single Line Chosen: ..............................................................................................10-9
Epson LX-300+II Printer.............................................................................................10-9
Ticket Chosen: ......................................................................................................10-9
Single Line Chosen: ..............................................................................................10-9
Roll Printer.................................................................................................................10-9
Slip Printer...............................................................................................................10-10
TOC - 4 TABLE OF CONTENTS March 15

CAPINTEC, INC. CRC®-25R
MOLY ASSAY............................................................................................................. 10-10
Mo99 Background................................................................................................... 10-11
Mo99 Assay ............................................................................................................ 10-13
Tc99m Assay ..........................................................................................................10-14
Moly Assay Results................................................................................................. 10-14
ENHANCED TESTS......................................................................................................... 11-1
GENERAL..................................................................................................................... 11-1
ENHANCED TESTS MENU.......................................................................................... 11-1
GEOMETRY TEST....................................................................................................... 11-2
Measuring with Syringe.............................................................................................11-2
Measuring with Vial...................................................................................................11-4
Measurement Results ...............................................................................................11-5
PERFORMING LINEARITY TEST ................................................................................ 11-6
Standard Test............................................................................................................11-7
First Measurement................................................................................................11-7
Second Through Last Measurements ................................................................... 11-8
Lineator Test...........................................................................................................11-10
Calicheck Test.........................................................................................................11-12
QUALITY CONTROL (QC) ......................................................................................... 11-14
Single Strip Test...................................................................................................... 11-15
Two Strips Test .......................................................................................................11-16
HMPAO Test...........................................................................................................11-19
MAG3 Test.............................................................................................................. 11-22
INVENTORY ....................................................................................................................12-1
GENERAL..................................................................................................................... 12-1
INVENTORY MENU ..................................................................................................... 12-1
ADDING TO THE INVENTORY.................................................................................... 12-2
Input Activity..............................................................................................................12-4
Measuring Activity.....................................................................................................12-6
Mo/Tc Ratio...............................................................................................................12-6
MAKING A KIT.............................................................................................................. 12-7
WITHDRAWING FROM INVENTORY ........................................................................ 12-10
PRINTING THE INVENTORY..................................................................................... 12-12
DELETING FROM INVENTORY................................................................................. 12-13
Deleting Individual Items from the Inventory............................................................ 12-13
Deleting All Items in the Inventory ........................................................................... 12-14
DOSE TABLE..................................................................................................................13-1
CALCULATION UTILITIES.............................................................................................. 14-1
GENERAL..................................................................................................................... 14-1
CONVERSION BETWEEN Ci and Bq (Ci ↔Bq).......................................................... 14-2
DECAY CALCULATION................................................................................................ 14-3
March 15 TABLE OF CONTENTS TOC - 5

CAPINTEC, INC. CRC®-25R
CLEANING AND MAINTENANCE ...................................................................................15-1
GENERAL.....................................................................................................................15-1
CLEANING and DISINFECTING...................................................................................15-1
Cleaning Instructions .................................................................................................15-1
Readout Unit and Chamber...................................................................................15-1
Liner/Dipper...........................................................................................................15-2
Printer....................................................................................................................15-2
Remote Display.....................................................................................................15-2
Disinfecting Instructions.............................................................................................15-2
Liner/Dipper...........................................................................................................15-2
PREVENTATIVE MAINTENANCE ................................................................................15-3
SERVICING...................................................................................................................15-3
DISPOSAL ....................................................................................................................15-4
FUSE SERVICING........................................................................................................15-5
Readout Fuses ..........................................................................................................15-5
Printer Fuse...............................................................................................................15-5
BATTERY REPLACEMENT ..........................................................................................15-6
TROUBLESHOOTING.................................................................................................15-12
Nothing appears on the display................................................................................15-12
Nothing happens when any key is pressed..............................................................15-12
Buzzer buzzes continuously.....................................................................................15-12
High background indication......................................................................................15-12
Zero activity is indicated with a source in the well. ...................................................15-13
Readings appear overly noisy for low activities........................................................15-13
Indication of significant negative activity...................................................................15-13
The time is reset to 00:00.........................................................................................15-13
Printer prints junk or prints with incorrect spacing. ...................................................15-13
Print head hangs up when printing tickets................................................................15-13
Printer will not respond.............................................................................................15-13
ACCESSORIES AND REPLACEMENT PARTS..........................................................15-14
SHIPPING...................................................................................................................15-15
APPENDIX I – Principle of the Calibrator
APPENDIX II – Calibration Numbers
APPENDIX III – Multiplication Factors for Non-Equilibrium Radioisotopes
APPENDIX IV – Operational Summary
INDEX
WARRANTY
DECLARATION OF CONFORMITY
TOC - 6 TABLE OF CONTENTS March 15

CAPINTEC, INC. CRC®-25R
PREFACE
Thank you for purchasing the Capintec, Inc. CRC®-25R Radioisotope Dose Calibrator. Every
effort has been made to insure that the information in this document is complete, accurate,
and up-to-date. Capintec, Inc. assumes no responsibility for the results of errors beyond its
control. Mention of products manufactured by other companies does not necessarily
constitute endorsement by Capintec, Inc.
Please address any comments pertaining to this manual to:
CAPINTEC, Inc.
620 Alpha Drive
Pittsburgh, PA 15238
Phone [phone]
Fax [phone]
CRC®-25R and CII are registered trademarks of Capintec, Inc.
Note: Federal Law restricts this device to sale by or on the order of a physician,
pharmacist or other licensed professional.
SYSTEM DESCRIPTION
The CRC®-25R Radioisotope Dose Calibrator consists of the following:
•Display Unit (Readout)
•Chamber
•Power Cord
•Printer (optional)
The Enhanced functions provide the following enhancements:
•Inventory Functions
•Geometry Test
•Linearity Tests
oStandard Test
oLineator
oCalicheck
•QC Tests
oSingle Strip
oTwo Strips
oTc99m HMPAO
oTc99m MAG3
February 15 PREFACE p - 1

CAPINTEC, INC. CRC®-25R
YEAR 2000 COMPLIANCE
The CRC®-25R measurement system contains information technology that accurately
processes date and time data between the years 1999 and 2000. These products, when
used in combination with products purchased from other manufacturers, whose products
properly exchange date and time information, will accurately process the date and time. All
future products are committed to meeting the same Year 2000 compliance.
MEDICAL EQUIPMENT SAFETY CLASSIFICATION
•CLASS I EQUIPMENT energized from an external power source.
•TYPE B EQUIPMENT with no applied parts to the patient.
•Ordinary EQUIPMENT without protection against the ingress of water or particulates
(IP00).
•Suitable for CONTINUOUS OPERATION.
•NOT suitable for use in an OXYGEN or a FLAMMABLE ENVIRONMENT.
ELECTROMAGNETIC INTERFERENCE POTENTIAL
This equipment complies fully with interference immunity requirements of the standard IEC
61326 “Electrical equipment for measurement control and laboratory use – EMC
requirements”.
This equipment generates radio frequency energy and, if not installed and used in
accordance with the instructions, may cause harmful interference to nearby devices.
However, there is no guarantee that interference will not occur in a particular installation. If
this equipment does cause harmful interference, the user is encouraged to try to correct the
interference by one of the following measures:
•Increase the separation between the equipment and the affected device.
•Plug the unit into an outlet on a circuit different from that which the affected device is
connected.
If this fails to correct the problem, please contact Capintec’s only Authorized Service Center.
p - 2 PREFACE February 15

CAPINTEC, INC. CRC®-25R
IMPORTANT SAFETY INFORMATION
The CRC®-25R measurement system has been carefully designed to provide years of safe
and reliable performance. As with all electrical equipment, however, there are basic
precautions that must be observed to avoid injuring yourself, the patient or damaging the
equipment.
•Follow the unpacking and assembly instructions document, and read this manual
carefully before using this equipment. Be sure to save all provided documents for
future reference.
•Understand all warning and caution labels as explained in CHAPTER 1: SAFETY
before operating this equipment.
February 15 PREFACE p - 3

CAPINTEC, INC. CRC®-25R
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CAPINTEC, INC. CRC®-25R
CHAPTER 1
SAFETY
These warnings and instructions for use form an integral part of the CRC®-25R and must
therefore be kept available for consultation at all times. Precise compliance with the
instructions is an essential condition for normal use, correct application and thus safety of the
user.
SYMBOL DEFINITIONS
Dangerous Voltage Present
Functional Earth Ground
Caution
Operator should consult accompanying documents
Fuse
Low Battery: Indicates that the internal Lithium Battery has
depleted.
AC Voltage
“ON” (power)
“OFF” (power)
Date of manufacture
 CE Mark
Waste in Electrical and Electronic Equipment (WEEE) – This
symbol indicates that the waste of electrical and electronic
equipment must not be disposed as unsorted municipal waste
and must be collected separately.
Environmentally Friendly Use Period (EFUP) – 20 years from
the date of manufacture – Toxic or hazardous substances or
elements contained in the unit will not leak or mutate under
normal operating conditions resulting in any environmental
pollution, bodily injury or damage to assets.
October 13 SAFETY 1 - 1

CAPINTEC, INC. CRC®-25R
WARNING AND CAUTION LABELS
Located on the back of the Readout Unit is a label, (Figure 1-1), providing the system power
requirements and the replacement fuse values for power line voltages.
CAUTION: Please reference CHAPTER 15: CLEANING AND MAINTENANCE,
SECTION: FUSE SERVICING for instructions on how to change the
fuses of the CRC®-25R.
CAUTION: A fire hazard may exist if the wrong size of fuse is installed.
Figure 1-1
Located on the bottom of the Chamber are 2 labels.
The first label, (Figure 1-2), contains statements denoting not to remove the cover because
there are no adjustments that the user can perform in the Chamber.
Figure 1-2
The second label (Figure 1-3) pertains to the electrical safety of the Chamber. It is necessary
because of the high voltage present (approximately 180 Volts DC) on the PC board installed
in the chamber. A screwdriver is necessary to remove the cover.
HAUTE TENSION
MISE EN GARDE
Figure 1-3
1 - 2 SAFETY October 13

CAPINTEC, INC. CRC®-25R
CAUTIONS AND NOTES
CAUTION: Only qualified/trained personnel should operate or service this unit.
CAUTION: If the equipment is used in a manner not specified in this manual, the
protection provided by the equipment may be impaired.
CAUTION: Do not store high activity radioactive samples in the CRC®-25R
Chamber(s). The Chamber is carefully designed for accurate and precise
measurements of high activity radioactive materials. It was not designed
to function as a long term storage vessel. Prolonged storage of high
activity radioactive samples in the Chamber may cause premature failure
of the unit.
CAUTION: In order to obtain a correct reading for a Test Source (Standard Source)
Vial, the supplied liner and dipper must be used to achieve the correct
geometry. The CRC®-25R is not designed to use syringe Test Sources in
any application.
CAUTION: Capintec, Inc. does not provide the calibration number for any type of
Brachytherapy source. The user should have the source calibrated by a
regional Accredited Dosimetry Calibration Laboratory (ADCL) site or
obtain a calibrated source from the manufacturer and perform your own
in-house calibration (All Brachytherapy sources used in IVBT
applications must be calibrated in an ADCL facility).
CAUTION: In order to obtain a correct reading for any Brachytherapy sources
including HDR & LDR, use the appropriate source holder for the source
type being measured to achieve the correct geometry. (e.g. I125 Seed
Holder, Ir192 Ribbon Holder, etc). When making a measurement, use
the same source holder that was used in determining the calibration
number. Verify that the liner has been removed from the chamber before
making the measurement. If additional information is needed, contact
Capintec, Inc. for further assistance.
CAUTION: In order to obtain a correct reading for any Brachytherapy sources used
in IVBT, use the appropriate source holder (Note that IVBT source
holders are individually serialized) for the source type being measured to
achieve the correct geometry. (e.g. Novoste Seed Holder). When making
a measurement, use the same source holder (same serial number) that
was used in determining the calibration number. Verify that the liner has
been removed from the chamber before making the measurement. If
additional information is needed, contact Capintec, Inc. for further
assistance.
CAUTION: IVBT source calibration is only to verify source output and is not to be
used in treatment planning.
October 13 SAFETY 1 - 3

CAPINTEC, INC. CRC®-25R
CAUTION: High voltage is present inside the Chamber (up to 180 Vdc). Due to the
presence of this high voltage, opening the covers with the system
plugged in may be hazardous. Refer all servicing to qualified personnel.
CAUTION: No internal adjustments inside the Readout or Chamber may be
performed by the user within the conditions of the warranty, except for
changing the fuse. Due to the presence of high voltages, opening the
cover with the system plugged in may be hazardous. Refer all servicing
to qualified personnel.
CAUTION: Except for Brachytherapy, never use the calibrator without the Chamber
Liner in place. Liners are inexpensive and easy to replace. A
contaminated Chamber is a very costly mistake. If the unit becomes
contaminated, remove the liner and clean the unit as stated in CHAPTER
15: CLEANING AND MAINTENANCE, SECTION: CLEANING and
DISINFECTING before operating.
CAUTION: Care must be exercised when moving the instrument or when
maintenance is performed. The shielded cylinder is heavy (13.6 kg or 30
lb.). In order to provide the required sensitivity, the wall of the ionization
chamber is extremely thin and the chamber is filled with pressurized gas.
It is therefore, essential to avoid mechanical shock or vibration of any
kind.
CAUTION: When working with a heavy sample (especially a CapMac or Moly Assay
Canister) always lower it gently into the Chamber. Dropping any heavy
object into the Chamber can cause permanent, expensive damage.
CAUTION: The use of multiplication and division factors in Calibration Numbers is
only to maintain a degree of consistency with other Capintec Dose
Calibrators. The CRC®-25R is a direct reading instrument. If
multiplication or division is required, the arithmetic will be done by the
system. The actual activity is displayed. DO NOT apply these factors to
the displayed activity yourself.
CAUTION: It is desirable to leave the unit powered at all times in order to prevent
moisture absorption and to maintain the stability of the instrument
(especially if the instrument is subjected to high humidity or low
temperature).
CAUTION: The sensitivity of the Chamber is somewhat dependent upon the vertical
position of the sample within the well. All calibrations were done with a
Standard Sample placed in the supplied sample holder (dipper). It should
be noted that in this configuration, the sample is not quite at the bottom
of the well. If, for any reason, you make a measurement without using
the dipper, be sure that the sample is in the correct vertical position. Both
the CapMac and the Standard Moly Assay Canister maintain the same
position as the dipper.
1 - 4 SAFETY October 13

CAPINTEC, INC. CRC®-25R
CAUTION: This equipment generates radio frequency energy and, if not installed
and used in accordance with the instructions, may cause harmful
Electromagnetic Interference (EMI) to nearby devices. However, there is
no guarantee that interference will not occur in a particular installation.
CAUTION: If any printer other than one of the models supplied by Capintec is used,
the safety of the unit may be compromised or Electromagnetic
Interference (EMI) may be introduced into other devices located in the
same general area as the CRC®-25R or the CRC®-25R may become
susceptible to EMI.
CAUTION: The unit contains lead. Appropriate caution should be taken if the interior
of the unit is exposed. The unit should be disposed of in accordance with
local and national regulations.
CAUTION: The unit contains a Lithium Battery. This should be disposed of in
accordance with local and national regulations.
CAUTION: The user should always verify the validity of any measurement or test
result in order to minimize measurement errors.
Note: It is recommended that periodic (every five years) re-calibration of the unit be
performed only by Capintec’s only Authorized Service Center (reference CHAPTER
15: CLEANING AND MAINTENANCE) to guarantee that the instrument's high
reliability is maintained).
October 13 SAFETY 1 - 5

CAPINTEC, INC. CRC®-25R
1 - 6 SAFETY October 13
GENERAL SAFETY TIPS
Unplug the equipment before cleaning it. Use only a damp cloth; do not use solvents
or aerosol cleaners.
To protect the equipment from overheating, do not use the equipment directly in front
of a radiator or heat register.
Do not use the equipment near water, or spill liquids of any kind into the equipment.
Be sure that your power source matches the rating listed on the CRC®-25R
Calibrator.
The CRC®-25R power cord has a grounded, 3-prong plug as a safety feature, and it
will only fit into a grounded outlet. Do not use an adapter to defeat the grounding.
To avoid damaging the power cord, do not place anything on it or place it where it will
be stepped on. If the cord becomes damaged, replace it immediately.
Aside from the routine maintenance described in this manual, do not try to service
this equipment yourself. Do not make any adjustments other than those outlined in
this manual, as you may in-validate the calibration or cause damage requiring
extensive repair work. Refer servicing to qualified service personnel.

CAPINTEC, INC. CRC®-25R
CHAPTER 2
FUNCTIONAL & TECHNICAL
DESCRIPTION
INTENDED USE
The CRC®-25R is intended to be used by trained Nuclear Medicine Technologists and
Physicians, for measuring the activity of a radioisotope samples for Nuclear Medicine and
Brachytherapy.
Also using the system are Health Physicists with expertise in nuclear medicine and radiation
safety – typically used for assessing reproducibility of counting instruments with various
Quality Assurance procedures (Linearity, Constancy, Accuracy, etc.).
OPERATOR PROFILE
The operator profile for the Nuclear Medicine Technologists, Physicians and Health
physicists is as follows:
•Education:
oMinimum: at least an Associate Degree
oNo maximum
•Knowledge:
oMinimum: Understands the basic concepts of nuclear medicine.
oNo maximum
•Language Understanding:
oEnglish
oOther languages are available for instructions for use
•Experience:
oMinimum: Has minimum training or is under surveillance by a trained user.
oNo maximum
OPERATOR TRAINING
This Owner’s Manual contains all of the information required to operate the CRC®-25R.
March 15 FUNCTIONAL & TECHNICAL DESCRIPTION 2 - 1

CAPINTEC, INC. CRC®-25R
FUNCTIONAL DESCRIPTION
The CRC®-25R provides a precise, accurate, fast and very convenient method of measuring
the activity of a radioisotope sample for Nuclear Medicine and Brachytherapy.
The activity of the sample will be displayed with a proper unit when a sample of unknown
strength (activity) of a known radioisotope is placed in the ionization chamber and the correct
calibration number is selected.
The sample must be placed in the same geometry as the reference source used to
determine the calibration number by using the appropriate source holder.
Note: For a detailed description of the basic principles of the calibrator, reference
APPENDIX I: PRINCIPLE OF THE CALIBRATOR.
Most radioisotopes can be measured in the Chamber.
Eight preset nuclide keys are provided for the most often used radioisotopes.
Five user assignable nuclide keys are provided for commonly used radioisotopes that do not
have a preset nuclide key.
Assays may be made reliably in the Chamber, from as low as 1 microcurie (0.1
megabequerel) for most radioisotopes to as high as 8 curies [200 giga (109) Becquerel] of
Tc99m.
The 6cm diameter and 25cm deep ionization chamber well allows convenient measurements
of virtually any radioisotope geometry in clinical use including whole generators, syringes and
seed trains.
The external shield of the ionization chamber protects users from exposure to intensive
radiation and reduces the effects from background radiation on low-level measurements.
2 - 2 FUNCTIONAL & TECHNICAL DESCRIPTION March 15