Cypress Diagnostics CYANSmart User manual

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www.diagnostics.be • Belgium • Tel: ++ 32 15 67 67 68 • e-mail: [email protected]
CYANSmart
Service Manual
For a clear and precise diagnose
CY009
English

Cypress Diagnostics: Nijverheidsstraat 8 • 2235 Hulshout • Belgium
www.diagnostics.be • Tel: ++ 32 15 67 67 68 • e-mail: [e-mail]
CY009 – CYANSmart – Service Manual
CYANSmart Service Service Manual, version 20191121 (8.0) Page 1
TABLE OF CONTENTS
1 INTRODUCTION .................................................................................................................................................. 3
1.1 SYSTEM DESCRIPTION .................................................................................................................................... 3
1.2 PRINCIPLE OF MEASUREMENT ....................................................................................................................... 3
1.3 TECHNICAL AND OPERATIVE SPECIFICATIONS ............................................................................................... 4
2 INSTALLATION ..................................................................................................................................................... 5
3 MAINTENANCE .................................................................................................................................................... 6
3.1 PUNCTUAL MAINTENANCE ........................................................................................................................... 6
3.2 ROUTINE MAINTENANCE ............................................................................................................................... 6
3.2.1 Washing 6
3.2.2 Cleaning 7
3.2.3 Verification 7
3.3 REPLACEMENT OF SPECIFIC PARTS ................................................................................................................ 8
3.3.1 External cleaning 8
3.3.2 Internal washing 8
3.3.3 Replacement schedule 8
4 TECHNICAL CONTROL ...................................................................................................................................... 9
4.1 GENERAL DESCRIPTION AND BLOCK DIAGRAM ............................................................................................. 9
4.2 MAIN CONTROL BOARD............................................................................................................................... 10
4.2.1 Connections on the mainboard 10
4.2.2 Voltage check points on the mainboard 11
4.2.3 Verification of the voltage to the mainboard 11
4.2.4 Replacement of the mainboard 12
4.3 OPTICAL SYSTEM ......................................................................................................................................... 12
4.3.1 Lamp 13
4.3.2 Filter wheel 13
4.3.3 Flow cell 13
4.3.4 Pre-amplifier board 14
4.3.5 Verification of the optical system 14
4.3.6 Cleaning and/or replacement of the flowcell 16
4.3.7 Verification of the filter wheel home sensor 17
4.3.8 Cleaning and/or replacement of the filter wheel home sensor 18
4.3.9 Verification of the filter wheel motor 19
4.3.10 Replacement of the filter wheel motor 19
4.3.11 Cleaning and/or replacement of filters 21
4.3.12 Verification of the voltage to the lamp 22
4.3.13 Replacement of the lamp 23
4.3.14 Replacement of the pre-amplifier board 26
4.3.15 Replacement of the optical system 26
4.4 HYDRAULIC AND ASPIRATION SYSTEM ........................................................................................................ 28
4.4.1 Verification of the aspiration and hydraulic system by pump calibration 28
4.4.2 Replacement of tubes in the hydraulic circuit 30
4.4.3 Replacement of peristaltic pump tube 31
4.4.4 Replacement of peristaltic pump rubbers 32
4.4.5 Cleaning and lubrication of the pump motor with rotor 32
4.4.6 Verification of the pump motor 33
4.4.7 Replacement of the pump motor with rotor 34
4.4.8 Verification of the aspiration switch 34
4.4.10 Replacement of the aspiration switch 35
4.4.11 Aspirate format 35

Cypress Diagnostics: Nijverheidsstraat 8 • 2235 Hulshout • Belgium
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4.5 INCUBATOR BLOCK ...................................................................................................................................... 36
4.6 TEMPERATURE ............................................................................................................................................. 36
4.6.1 Temp display 36
4.6.2 Temperature calibration 37
4.6.3 Cleaning and/or replacement of the fan of the optical system 39
4.6.4 Verification of the Peltier element 40
4.6.5 Replacement of the Peltier element 40
4.6.6 Verification of the heater element of the incubator 41
4.6.7 Replacement of the heater element of the incubator 42
Verification of the temperature sensor 43
4.6.8 43
4.6.9 Replacement of the temperature sensor 44
4.6.10 Verification of the voltage going to the heater elements on the mainboard 44
4.7 THERMAL CARBON PRINTER ........................................................................................................................ 45
4.7.1 Install or change the print paper 45
4.7.2 Verification of the voltage to the printer on the mainboard 46
4.7.3 Replacement of the printer 46
4.8 TOUCH SCREEN ............................................................................................................................................ 47
4.8.1 Touch screen calibration methods 47
4.8.2 Adjustment of the screen brightness 48
4.8.3 Verification of the voltage to the touch screen on the mainboard 48
4.8.4 Replacement of the touch screen cable 48
4.8.5 Functional verification of the parts of the touch screen 49
4.8.6 Replacement of the touch screen 50
4.9 POWER SUPPLY ........................................................................................................................................... 51
4.9.1 General electricity and installation requirements 51
4.9.2 Replacements of fuses 52
4.9.3 Locating power problem 53
4.9.4 Verification of the fuses 54
4.9.5 Verification of the power plug connector and power switch 54
4.9.6 Verification of the power supply 56
4.9.7 Cleaning and/or replacement of the fan for power assembly 57
5 VALIDATION ....................................................................................................................................................... 58
5.1 PREPARATION OF A DILUTION SERIES .......................................................................................................... 58
5.1.1 Ammonium colbalt (II) sulfate hexahydrate (powder) 58
5.1.2 Potassium dichromate (powder) 59
5.1.3 Magnesium Xylidyl Blue (liquid) 59
5.2 VERIFICATION OF PRECISION ....................................................................................................................... 59
5.3 VERIFICATION OF LINEARITY ........................................................................................................................ 60
5.4 VALUE 60
6 TROUBLESHOOTING ........................................................................................................................................ 61
6.1 OPERATIONAL ............................................................................................................................................. 61
6.2 TECHNICAL .................................................................................................................................................. 63
7 SAFETY INFORMATION ................................................................................................................................... 65
INSTALLATION FORM
MAINTENANCE FORM
REPAIR FORM
SPARE PARTS

Cypress Diagnostics: Nijverheidsstraat 8 • 2235 Hulshout • Belgium
www.diagnostics.be • Tel: ++ 32 15 67 67 68 • e-mail: [e-mail]
CY009 – CYANSmart – Service Manual
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1 INTRODUCTION
1.1 SYSTEM DESCRIPTION
The CYANSmart is an easy to operate semi-automatic biochemical analyzer. It is a microcomputer-based
independent unit, controlling several systems: built-in thermal printer, touch screen, optical detection
system with flowcell, incubator and aspiration system.
1. Thermal printer
2. Touch screen
3. Optical system
4. Incubator block
5. Peristaltic pump
6. Aspiration “Push” button
7. Inlet tube
8. Rear panel
WARNING! Please read the service manual before opening the CYANSmart and performing problem
diagnosis or replacements.
BIOHAZARD: Wear personal protective equipment. Use universal precautions. See chapter 8. Safety
information for recommended precautions when working with biohazard materials.
1.2 PRINCIPLE OF MEASUREMENT
The CYANSmart is a semi-automated biochemistry analyzer. Samples are prepared manually outside the
instrument and after an incubation period (in- or outside the instrument) the samples are measured in the
flowcell and the analyzer calculates the result.
A halogen lamp emits light which passes through a filter selecting the required wavelength. The light then
passes through the sample in the flowcell. The sample will transmit or reflect fractions of the light. The
detector will measure how much light was reflected from/transmitted through the sample. This
measurement is then amplified and converted to a digital number for further calculations. These
calculations can be performed because there is a relationship between how much light is
reflected/transmitted and the concentration of the substances in a sample.
Lamp Filter Flowcell Photodiode detector
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④
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③
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8

Cypress Diagnostics: Nijverheidsstraat 8 • 2235 Hulshout • Belgium
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1.3 TECHNICAL AND OPERATIVE SPECIFICATIONS
Optical system
Flowcell 32 µl, 10 mm light path
Min. reaction volume 500 µl per test
Light source Halogen lamp 6V / 10W
Photo detector Silicon based (range 300 – 900 nm)
Measurement range 0,000 – 3,500 Abs
Wavelength 340 – 620 nm
Wavelength selection Automatic via 7 interference filters: 340nm, 405nm, 492nm, 510 nm,
546nm, 578nm, 620nm
Flowcell
 25°C, 30°C, 37°C, ambient temperature (R.T.)
 Peltier element
 Thermostatic control: PID controlled, ± 0.5°C
Incubator
 20 places with 14 mm diameter
 37°C
 Thermostatic control: PID controlled, ± 1°C
Display
 Back-illuminated LCD
 Touch screen calibration possible
 800 x 480 pixels (screen size: 7.0 Inch, 155.3 x 88 mm)
Printer
 Automatic or on-demand printing
 Built-in thermal printer
 24 characters per line, prints graphs
Software
Data storage 180 test methods and 6000 sample test results
Methods Cypress methods pre-programmed at delivery
Languages English, French, Spanish
Quality control feature 2 controls programmable
Separate QC result menu with (printable) graphs
Calculation methods Absorbance, end point, two-point, kinetic, bichromatic
Calibration methods Factor, calibrator and multi-point calibration
Blank options Sample blank, reagent blank and distilled water
Incubation time 0 – 999 seconds
Reading time 3 – 999 seconds
Power supply
 AC 220 V ± 10 %, 50 Hz ± 2 % or AC 110 V ± 10 %, 60 Hz ± 2 %
 Automatic voltage and hertz switch
 Grounding required
 2 fuses T2AL250V
 Power: 200VA, reduced to 140 VA in standby mode
 Power save / Standby mode
Weight and dimensions
 Instrument: 9 kg, 435 x 415 x 200 mm (LxWxH)
 Packed in box: 11.5 kg, 520 x 430 x 260 mm (LxWxH)
Environmental requirements
 Ambient temperature: 15°C – 30°C
 Storage temperature: 5-50°C
 Relative humidity: 30 % - 70%
 Air pressure: 860 hPa – 1060 hPa

Cypress Diagnostics: Nijverheidsstraat 8 • 2235 Hulshout • Belgium
www.diagnostics.be • Tel: ++ 32 15 67 67 68 • e-mail: [e-mail]
CY009 – CYANSmart – Service Manual
CYANSmart Service Service Manual, version 20191121 (8.0) Page 5
2 INSTALLATION
The CYANSmart is an easy to operate instrument with integrated user-friendly software. No additional
computers or instruments are needed for good operations. In order to fully guarantee the performance of
the CYANSmart, it is extremely important that it is correctly installed.
If the installation, usage and maintenance directions are not followed correctly and/or safety indications are
not respected, Cypress Diagnostics cannot guarantee correct functioning of the instrument. Misuse can
compromise the safety of the operator and his surroundings and will void the warranty. Consumables are
not included in the warranty.
WARNING! Do NOT discard the carton box or protection material! If you need to ship the instrument (for
example for service), be sure to use the original packing materials. Other forms of commercially available
packing are not recommended and can void the warranty.
At installation, it is strongly recommend to fill in the installation form. It contains essential information and
also provides a short checklist of all installation requirements.
The serial number can be found on the back label. This is essential information in every communication
regarding the analyzer. The software version can be found in the System Settings – System Info.
Packing list:
Code Description Quantity
CY009 CYANSmart Analyzer 1
- User manual including application sheets 1
- CD with PC software (from P/D 2016/09 on) 1
CY004/9-S28 Waste tube 1
CY004/9-S44 Waste bottle 1
CY004/9-S22 Aspiration button 1
CY004/9-S49 Power cord 1
CY004/9-S48 Fuse T2AL250V 2
CY009-S11 Lamp with frame, cable and connector 1
CY009-S25 Pump tube 1
CY001-S01 Thermal print paper 5
CY004/9-S43 Dust cover 1
CY009-S56 USB cable (from P/D 2016/04 on) 1
For the detailed description of the installation, please check the user manual Chapter 2.
After turning off the analyzer, you need to wait at least 60 seconds before turning it on again!
Otherwise, the fuses will blow because of the residual current.
②

Cypress Diagnostics: Nijverheidsstraat 8 • 2235 Hulshout • Belgium
www.diagnostics.be • Tel: ++ 32 15 67 67 68 • e-mail: [e-mail]
CY009 – CYANSmart – Service Manual
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3 MAINTENANCE
This chapter contains all routine operations concerning instrument maintenance. The procedures, listed
and described below, should be carefully followed in order to guarantee the manufacturers quality
specifications and the perfect working conditions of the instrument over time.
The CYANSmart requires three levels of maintenance:
 Punctual maintenance: at special moments such as at installation
 Routine maintenance: to maintain the level of precision day in day out
 Special maintenance: replacement of specific parts
Please consult the maintenance form for an overview of the different maintenance actions. In case of repair,
please register all undertaken actions in the repair form and sign it in order to keep track of the
interventions.
3.1 PUNCTUAL MAINTENANCE
The punctual maintenance should be effectuated at installation and before or after a long period of
inactivity. The following points of attention should be considered:
 Check the installation instructions.
 Check all tubes visually for leaking or squashing. Pay special attention to the peristaltic pump
tube. Replace if necessary.
 Removing dust from the instrument.
 Wash the flowcell with a detergent (CYAN Wash Solution CY001-WS or 5% Tween 20) and rinse
the flowcell with distilled water.
 Disinfect the flowcell with a 5% Hypochlorite solution and rinse with distilled water.
 Check the pump calibration.
 Check the AD auto zero and replace the lamp/filters if necessary.
 In case the instrument will not be used for a long period:
o Remove all liquid inside the instrument by aspirating air.
o Disconnect the pump tube.
3.2 ROUTINE MAINTENANCE
Frequency What Cleaning solution
Between methods Rinsing Distilled water
End of the day
Washing
Detergent + rinse with distilled water + rinse with air
Every week
Detergent + sodium hypochlorite (diluted 5 %) + rinse
with distilled water + rinse with air
End of the day (outside) Cleaning CYDIS surface/detergent + dust cover
Every 6 months (inside) Pressurized air (by service engineer)!
Every morning Verification AD auto zero
Every week Pump calibration
3.2.1 WASHING
i. Between tests
Between methods, always rinse the flowcell with distilled water.
It is not necessary to wash the instrument between different samples for the same method. However:
 In case of high risk of cross-over, you could pre-rinse the flowcell by aspirating distilled water, followed
by air (to avoid dilution) between the samples.
 In case of a strongly colored reagent, it might be necessary to pre-rinse the flowcell with (working)
reagent before aspirating the first measurement. Otherwise the first measurement could be
influenced by the distilled water used to zero the instrument.

Cypress Diagnostics: Nijverheidsstraat 8 • 2235 Hulshout • Belgium
www.diagnostics.be • Tel: ++ 32 15 67 67 68 • e-mail: [e-mail]
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ii. Daily washing
At the end of each working day, wash the instrument with a neutral detergent (CYAN Washing Solution
CY001-WS or 5% Tween 20):
1. Position the detergent solution under the inlet pipe.
2. Press the “Tube Wash” button at least 10 times (=15 mL).
3. Repeat this operation using air at least once to make an air gap between the detergent and the distilled
water.
4. Repeat this operation using distilled water at least 10 times (=15 mL) to rinse the system.
5. Repeat this operation using air at least 10 times (=15 mL) to dry the hydraulic system and avoid
microbiological contamination.
iii. Weekly washing
After a week of work, wash first with 15 ml detergent (end of day procedure); and then disinfect the
hydraulic system (tubes and flowcell) with 5% sodium hypochlorite (bleach).
1. Position the hypochlorite solution under the inlet pipe.
2. Press the “Tube Wash” button at least 10 times (=15 mL).
3. Incubate the hypochlorite in the flowcell for about 10 minutes (no longer!).
4. Aspirate air (1x) and then rinse the instrument with distilled water (10x) and air (10x).
NOTES:
a. In case of air bubbles (visible during AD auto zero or perform test) rinse with diluted sodium
hypochlorite (5 %) then rinse with distilled water (10x), and with air (10x).
b. This diluted sodium hypochlorite is normally market available. Please use only good trademarks. Cheap
ones contain contaminating solutions.
c. Always dilute the sodium hypochlorite for 5%, never use it undiluted! This will damage the
instrument.
d. Do not use corrosive detergents to wash the instrument.
3.2.2 CLEANING
i. Daily cleaning
Please notice that the instrument, especially the optical system and the electrical circuit, are sensitive to
dust. Avoid using the instrument in dusty spaces. Cover the instrument when not in use and keep the
printer, pump and flowcell cover closed during use.
At the end of each working session, dampen a tissue with a non-abrasive detergent like CYDIS Surface (Cod.
CYDIS-S) or a 6% ESOFENOL solution and wipe the outside of the instrument.
ii. Every 6 months
It is recommended to clean the dust from inside the instrument at least every 6 months. To do so, remove
the cover and blow the dust off the instrument using pressurized air. Make sure the air is completely dry!
Open the filter cover and blow the dust off.
NOTES:
 The instrument cover should only be removed when the CYANSmart is unplugged.
 We strongly advise to leave this procedure to the technical assistance of the service engineer of your
distributor.
3.2.3 VERIFICATION
i. Daily
Perform an AD auto zero
ii. Weekly
Perform a pump calibration

Cypress Diagnostics: Nijverheidsstraat 8 • 2235 Hulshout • Belgium
www.diagnostics.be • Tel: ++ 32 15 67 67 68 • e-mail: [e-mail]
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3.3 REPLACEMENT OF SPECIFIC PARTS
Before replacing any instrument part, repairing any defective item or performing any instrument
maintenance procedure(s), the operator or maintenance technician must carry out the below-described
decontamination procedure of the instrument part(s) involved in the operation(s).
3.3.1 EXTERNAL CLEANING
Use CYDIS Surface Cod. CYDIS-S or a 6% ESOFENOL solution (60 cc in one liter of distilled water). These are
antibacterial and antiviral substances.
 Spray the solution all over the instrument.
 Allow the solution to stand for approximately 30 minutes.
 Wipe the solution off the instrument using a sponge dampened with distilled water.
3.3.2 INTERNAL WASHING
Wash first with 15 ml detergent (end of day procedure); and then disinfect the hydraulic system (tubes and
flowcell) with 5% Hypochlorite (bleach). Make sure to incubate for 10 minutes (no longer) and then rinse
sufficiently with distilled water (procedure weekly washing).
3.3.3 REPLACEMENT SCHEDULE
Some spare parts should be replaced after a fixed period of time to ensure the good performance of the
analyzer. Please check the table below:
Spare part Replacement, when? Who?
Peristaltic pump tube Every six months User / Service engineer
All tubes of hydraulic
circuit
Every year or in case of leakage, obstruction or
strong coloration
Service engineer
Lamp Every year Service engineer
Amplifier board Every 2/3 years (together with lamp replacement) Service engineer
Peristaltic pump
rubbers
Every 2/3 years (together with pump tube
replacement)
Service engineer
Connectors Every 2/3 years (together with the replacements of
the tubes)
Service engineer
Flow cell In case of leakage, obstruction or strong coloration Service engineer