Diagnoptics AGE Scanner User manual

Introduction
Thank you for purchasing the AGE Scanner. Please read this manual carefully
and follow its instructions before using this product in order to familiarize
yourself with its capability and to ensure an accurate measurement result.
The AGE Scanner developed by DiagnOptics Technologies B.V. is an optical
consumer device that provides a measurement of the concentration of
Advanced Glycation Endproducts (AGEs) in human skin tissue. The process of
accumulation of AGEs in tissue is commonly known as glycation.
The AGE Scanner is used with either the myAGEnow, BodyAge or SkinAge app
on your mobile phone or tablet (Android, iOS) through a Bluetooth® connection.
These apps are available from the Google Play Store and Apple App Store.
The new triple mode provides improved measurement accuracy by ensuring that
any biological variation across the skin is minimized (explained in section 3.2).

1 Getting started
1.1 What is in the box
The following items are included in the box:
AGE Scanner
User Manual
2x AAA batteries
Scanner ID card
Drawstring bag
1.2Prepare your mobile device
To get started first prepare your mobile device by following these steps:
1. Install the AGE Scanner app of your choice (myAGEnow, BodyAge or
SkinAge) (see Chapter 2) from one of these online stores:
The Apple® App Store® for iOS devices such as an iPhone® or iPad®.
The Google Play™ Store for Android devices.
2. Turn on the Bluetooth® function of your mobile device.
1.3 Prepare your AGE Scanner
Before the AGE Scanner can be used the batteries need to be placed. To open
the battery compartment, slide off the battery cover located at the bottom of
the device by applying a gentle pressure on the embossed ring.
Inside the battery compartment you will find a label including instructions on
how to position the batteries. This label also includes important information
such as the serial number of the device. The serial number can also be found on
the Scanner ID card.
Supported AAA battery types: alkaline batteries

After placing the batteries the AGE Scanner can be turned on:
1. Start the AGE Scanner by pressing the button on the topof the device
once.
2. The ring around the button lights up blue as the AGE Scanner
searches for a Bluetooth® device to pair with.
3. Open the AGE Scanner app of your choice (myAGEnow, BodyAge or
SkinAge) on your mobile device and choose ‘next’ to display the
available AGE Scanner device(s).
4. Select the serial number of the AGE Scanner you want to connect to.
5. After successful pairing of the AGE Scanner with your mobile device
the ring around the button will change from blue to green.
During the initialization, the device’s internal light sources are switched on
briefly. This is completely harmless.
When no Bluetooth® connection can be established, the AGE Scanner will turn
itself off after 2 minutes.
1.4Switching off the AGE Scanner
The AGE Scanner can be switched off by briefly pressing the button on top of the
device twice in quick succession. The AGE Scanner will also switch itself off
automatically after approximately 2 minutes of inactivity.
1.5Bluetooth® compatibility
The AGE Scanner is compatible with mobile devices that run Android (version
4.3 or higher) and iOS operating systems and support Bluetooth® 4.1 or higher
(Bluetooth Low Energy (BLE)). Please see chapter 7 for further product
specifications.

2 Apps
The following free apps are available for operating the AGE Scanner. The app of
your choice can be downloaded from the Apple® App Store® for your iPhone®
or iPad® and from the Google Play™ Store for your Android phone or tablet.
All apps allow viewing of the measurement result, support both triple and single
measurement mode and result sharing.
2.1 myAGEnow
The myAGENow app is intended for health applications that require direct
reporting of the AGE score. In the result screen of this app a further comparison
is made with the mean score for healthy individuals of the same age. What is
reported is the percentage with which the measured score deviates from the
average score at the calendar age of the client.
2.2 BodyAge
The BodyAge app is intended for healthy aging applications that require a
measure of the biological age of the client. This app automatically calculates this
age based on the measurement result and reference data for healthy individuals
from the scientific literature.
2.3 SkinAge
The SkinAge app is intended for skin aging applications that require a measure
of the skin age of the client. This app automatically calculates this age based on
the measurement result and reference data for healthy individuals from the
scientific literature.

3 Performing measurements
3.1Measurement instructions
The AGE Scanner gives a correct measurement result provided that the following
conditions are met:
The AGE measurement is performed directly on healthy skin. The skin at
the measuring area should be homogeneous and free of birthmarks,
tattoos or excessive hair growth and without recent exposure to skin
creams or any substance that may have fluorescent properties. Self-
tanning agents should not be used for at least 10 days before a
measurement. Sun-blockers and other skin care products should not be
used for 3 days before a measurement.
The measurement head of the AGE Scanner is positioned on the inner
forearm at about 8cm (3 inches) from the elbow. See the illustrations on
the next page.
The silicon ring of the measurement head of the AGE Scanner is pressed
gently to the skin evenly on all sides such that ambient light cannot enter
the measurement window.
Both the AGE Scanner and the person’s arm are kept still during the
measurement.
The measurement window is kept clean (see chapter 5.1).
3.2Performing a measurement
To perform a measurement on a person please do the following:
1. Make sure you have completed all preparation steps in chapter 1.
2. For the best possible accuracy of the measurement result make sure that
the triple mode is selected in the Settings menu in the app.
Alternatively, select single mode for the fastest result at a lower accuracy.
3. Place the AGE Scanner on the person’s dominant forearm (see the
illustrations on the next page) with gentle pressure and avoid ambient light
entering the device. Please make sure to use the prescribed measurement
location (see section 3.1).
4. Start the measurement by pressing and releasing the button.

Measurement locations in triple mode (most accurate result). The distance
between the three measurement locations is about 1-2 cm. :
Measurement location in single mode (fastest result):

5. During a measurement, the ring around the button turns orange. Avoid
movements of the arm and the AGE Scanner during that time. When using
triple mode re-position the AGE Scanner when the LED ring around the
button of the AGE Scanner blinks green.
6. When the measurement is successfully completed, the LED ring blinks
green for four seconds and the measurement result is displayed in the app.
3.3LED ring
The color of the LED ring around the button of the AGE Scanner changes
depending on the status of your device. Please find below an overview of the
different device statuses:
Blue continuous
Available for mobile device connection with any
mobile device
Green
Connected
Orange
Measuring
Green blinking
Measurement successful!
Red
Error (see section 5.2 for further information)
3.4Biological variation and measurement results
Tissue glycation can vary over time. For example, for healthy individuals the AGE
value has been shown to increase with calendar age by 10-20% in 10 years.
Tissue glycation can also vary from one skin location to another. If used as
instructed the typical difference between measurements on the same location
of the same arm is within +/-10%.

4 Updating your AGE Scanner
Firmware updates are made available via the Diagnoptics Service app using Over
The Air (OTA) technology via the Bluetooth® connection.
4.1 How to update
Please follow these instructions to update the firmware through the Bluetooth®
connection:
1. Download the “Diagnoptics Service app”from the Apple® App Store®
or Google Play™ Store.
2. Turn on the Bluetooth® function of your mobile device and make sure
that you have an internet connection.
3. Open the Diagnoptics service app on your mobile device.
4. Select the serial number of the AGE Scanner you want to update from
the list of available devices.
5. After connecting, the app will check if a new firmware version is
available. If a firmware update is available you can start a download
by pressing ‘Update Firmware’.
6. After the update process is started the AGE Scanner will switch to
update mode and the LED ring will turn purple.
7. The Diagnoptics Service app will transfer the new firmware to the
AGE Scanner. The progress of the transfer will be shown in the
progress bar.
8. After a successful update the AGE Scanner will automatically reset
and reconnect to the Diagnoptics Service app. Press ‘Complete’ to
finish the update and to disconnect from the device.
4.2 What to do when an update fails
When an update fails, the device might remain in update modeuntil a successful
update has been performed. Pressing the ‘Retry’ button after an error occurs
will in most cases suffice to successfully update the device. When this does not
work, try one of the following solutions:

Situation:
Solution:
1
LED ring is off
Return to the list of available devices and turn on the
AGE Scanner, reconnect and retry updating the
device. If, after turning on, the LED ring is purple
please continue as described at situation 3.
2
LED ring is blue
Return to the list of available devices, reconnect and
retry the update.
3
LED ring is purple
Return to the list of available devices, select device
‘MFR_BOOT’ and retry the update.
Note: when the AGE Scanner is in update mode, no
device status information will be shown in the app.
4
Device does not
respond
When the AGE Scanner is stuck in update mode, it
will switch off automatically after one minute of
inactivity. If this is not the case and you cannot
connect to the device, reset the device by removing
the batteries and reinstalling them.
5
Device does not
switch to update
mode
After starting an update, the Service app will put the
AGE Scanner in update mode (purple LED ring). If this
is not the case and the AGE Scanner remains in
normal mode (green or blue LED ring) causing the
update to fail, disconnect and close the app. Then
turn on the AGE Scanner and wait for the LED ring to
turn on. Press and hold the button for 30 seconds
until the LED ring turns purple. (Note: after ten
seconds the LED ring will first turn red. Keep holding
the button until the LED ring turns purple).
The AGE Scanner is now in update mode. Open the
Diagnoptics Service app and continue as described
under situation 3.

5 Cleaning your AGE Scanner
5.1 Cleaning instructions
5.1.1 Measurement window
With proper storage and usage the AGE Scanner hardly requires cleaning apart
from dust removal. To ensure an accurate measurement result the
measurement window can be cleaned with a cotton swab or a pre-moistened
lens cleaning wipe, ideally using a standard 70% alcohol solution.
Avoid scratching the window by carefully handling the device during use and by
storing it in the box or drawstring bag when it is not used.
5.1.2 Skin interface
The silicon skin interface of the measurement head can be cleaned with
standard mild cleaning agents. When desired this skin interface can also be
disinfected with alcohol or chlorohexidine.

6Troubleshooting your AGE Scanner
6.1 Bluetooth® connection
In case of a connection problem first make sure that the Bluetooth® connection
on your mobile device is turned on.
If the connection problem persists open the AGE app, go to the settings menu
and choose ‘Reconnect AGE Scanner’. Follow the instructions in the app to
reconnect with the AGE Scanner.
6.2 Warning messages
Low battery
When the AGE Scanner is unable to perform a measurement due to low battery
power the ring around the button of the device turns red and a low battery
warning indication is shown in the App. Please replace the batteries (section 1.2)
and restart the device.
6.3 Error messages
When the AGE Scanner is unable to perform a measurement, the measurement
is aborted and an error indication is displayed in the app. You may receive one
of the following three error indications:
Measurement setup error
In case the measurement ring of your device is not placed properly on the
person’s skin, ambientlight mayreach the detectors and cause interference. The
AGE Scanner is capable of detecting such unwanted light. When this occurs, the
measurement is aborted and an ‘Ambient light error’is displayed in the app.
Low signal error
In case the measured signal from the person’s skin is too low, the device is
unable to perform a reliable measurement. When this occurs, the measurement
is aborted and a ‘Low signal error’is displayed in the app.
In general, a ‘Low signal error’is the result of the person’s skin having too much
pigment to allow for a reliable measurement (e.g. birth marks, freckles or
strongly pigmented skin).

External error
An ‘External error’is displayed in the app when the measurement is out-of-
bounds. When the ‘External error’ persists, your device may need to be re-
calibrated. Please contact Diagnoptics for support.

7AGE Scanner specifications
7.1 Technical specifications
•Operation Continuous indoor operation
•Power 3 VDC from two exchangeable AAA batteries
•Dimensions Width: 60mm, Depth: 170 mm, Height: 55 mm
•Weight 150g
•Operating Conditions Indoors
Temperature range: Lower limit 10°C - Upper limit + 30°C
Relative humidity: 20% to 75% non-condensing
Storage & Transport Conditions
Temperature range: Lower limit - 40°C - Upper limit + 70°C
Relative humidity: 10% to 100% non-condensing
Wireless communication
Method: Bluetooth Low Energy
ISM frequency band: 2402 –2480MHz
Rated power: 6mW
7.2 Classifications
Elec. shock protection Class III equipment
Standard(s)
Electrical Safety: EN 60950-1:2006 (up to: A12:2011)
EMC: EN 301 489-1 & EN 301 489-17 V2.2.1
Telecom: EN 300 328 v 1.9.1
FCC: 47 CFR part 15, Subpart 15C & 15.247
CMIIT ID: 2019XXXXXX
EM Exposure Safety: EN 62479:2010
Japanese Radio Law: Article 38-24, Paragraph 1
Safety of lamps: IEC 62471:2008
Hazardous Substances: 2011/65/EU (ROHS II)
SJ/T 11364-2014 PRC (ROHS II)
Waste: 2012/19/EU (WEEE)

8Regulatory & Safety Notices
8.1 Safety statement
This equipment has been tested to comply with safety certification in
accordance with the specifications of EN Standard: EN60950-1:2006.
8.2 USA: Federal Communications Commission (FCC) statement
This device complies with FCC part 15 FCC Rules.
Operation is subject to the following two conditions:
1. This device may not cause harmful interference and
2. This device must accept any interference received, including interference
that may cause undesired operation.
FCC Warning
Changes or modifications not approved by DiagnOptics Technologies B.V. will
void the user’s authority to operate the equipment.
This device meets the FCC requirements for RF exposure in public or
uncontrolled environments.
FCC ID: 2AKA5-MFR
8.3 European Union
Declaration of Conformity with Regard to the EU Directive 1999/5/EC R&TTE.
DiagnOptics Technologies B.V. is authorized to apply the CE Mark on device type
MSC00100, thereby declaring conformity to the essential requirements and
other relevant provisions of Directive EN 300 328 V1.8.1 and other applicable
Directives.
7.4Japan
This device has been granted modular approval for sale and operation in Japan.
Classification of specified radio equipment: Article 2, Clause 1, Item 19 2,4GHz
Wide Band Low Power Data Communication.
This certification by type has been granted in accordance with the provisions of
Article 38-24, Paragraph 1 of the Radio Law.

8.5 China
This device complies with SRRC (State Radio Regulatory Commission) regulations
administered by the Ministry of Industry and Information Technology of the
People's Republic of China.
DiagnOptics Technologies B.V. is authorized to apply the SRRC approval code
(the so called: ‘China MIIT ID’) on device type MSC00100, thereby declaring
conformity to the SRRC provisions.

9Disposal and recycling information
The symbol on the product or its packaging signifies that this product must be
disposed of separately from ordinary household wastes at its end of life
(according to Directive 2012/19/EU).
Please kindly be aware that it is your responsibility to dispose of electronic
equipment at recycling centers to help conserve natural resources.
Each country in the European Union should have its collection centers for
electrical and electronic equipment recycling. For information about your
recycling drop off point, please contact your local related electrical and
electronic equipment waste management authority or the retailer where you
bought the product.
•Do not dispose of your AGE Scanner with household waste
•Disposal of the packaging and your AGE Scanner should be done in
accordance with local regulations.
•Batteries are not to be disposed of in the municipal waste stream and
require separate collection.
This symbol (China RoHS II) indicates that this electrical product does not
contain any hazardous substances exceeding concentration limits and is a
green environmentally friendly product (the artistic style “e” in the middle of
the logo), which can be recycled if not casually discarded (curved arrows form a
circulating circle).

10 Liability and warranty
10.1 Liability
DiagnOptics Technologies B.V. and its respective directors, officers, employees
and agents and their respective successors, heirs and assignees, are not liable
for any damages, losses, obligations, costs and expenses, including attorney’s
fees that may be incurred by third parties in connection with a claim for damage
to or loss of tangible personal property, breach of warranty, or for bodily injury,
sickness and/or death sustained by any customer (collectively “Damage”) if or
where the damage is caused by or arises from any instance regarded as (a)
improper use of the AGE Scanner, (b) unauthorized modification of the AGE
Scanner, (c) fault or negligence by the user, (d) breach of any warranty or other
obligation by the user or (e) invalid or incorrect conclusions, and any
consequences thereof, drawn by third parties from the measurement results
provided by the AGE Scanner.
10.2 Warranty
The warranty supplied with this AGE Scanner System is provided by DiagnOptics
Technologies B.V.
10.3 Declaration of Conformity
The Declaration of Conformity can be provided to you on request. Please contact
DiagnOptics Technologies B.V. to request a copy of the Declaration of
Conformity.
Footnote
“The Bluetooth® word mark and logos are registered trademarks owned by
Bluetooth® SIG, Inc. and any use of such marks by ‘DiagnOptics Technologies
B.V.’ is under license. Other trademarks and trade names are those of their
respective owners.

Manufactured by:
DiagnOptics Technologies B.V.
Aarhusweg 4-9
9723 JJ Groningen
The Netherlands
[e-mail]
www.diagnoptics.com
Date of issue
06-2021
Doc. no.: DI-F-01-009.3