Endress+Hauser analytikjena CyBio Carry User manual

Assembly Instructions
CyBio Carry

Manufacturer Analytik Jena GmbH
Konrad-Zuse-Strasse 1
07745 Jena / Germany
Phone: [phone]
Fax: [phone]
Email: [email protected]
Technical Service Analytik Jena GmbH
Konrad-Zuse-Strasse 1
07745 Jena / Germany
Phone: [phone]
Fax: [phone]
Email: [email protected]
General Information http://www.analytik-jena.com
Documentation Number 30-3951-1xx-23E
Edition A (05/2022)
Technical Documentation Analytik Jena GmbH
© Copyright 2022, Analytik Jena GmbH
For a proper and safe use of this product follow the instructions. Keep the
operating manual for future reference.

CyBio Carry Table of contents
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Table of contents
1 Basic information ................................................................................................................................................. 5
1.1 About these assembly instructions.................................................................................................................. 5
1.2 Intended use ..................................................................................................................................................... 6
2 Safety.................................................................................................................................................................... 7
2.1 General.............................................................................................................................................................. 7
2.2 Safety labeling on the device ........................................................................................................................... 7
2.3 Danger zone...................................................................................................................................................... 8
2.4 Safety instructions for operation ..................................................................................................................... 9
2.5 Safety instructions – protection against explosion and fire........................................................................... 10
2.6 Safety instructionsformaintenance and repair.............................................................................................. 10
2.7 Safety instructions: Transport.......................................................................................................................... 10
2.8 Behavior during emergencies .......................................................................................................................... 11
3 Technical description............................................................................................................................................ 12
3.1 Setup and operating principle.......................................................................................................................... 12
3.2 Connections and interfaces.............................................................................................................................. 16
3.3 Labware requirements ..................................................................................................................................... 17
3.4 Scope of delivery............................................................................................................................................... 18
4 Installation and commissioning ........................................................................................................................... 19
4.1 Installation conditions...................................................................................................................................... 19
4.1.1 Ambient conditions .......................................................................................................................................... 19
4.1.2 Spatial requirements ........................................................................................................................................ 19
4.1.3 Power supply..................................................................................................................................................... 19
4.2 Commissioning ................................................................................................................................................. 20
4.3 Device configuration......................................................................................................................................... 21
4.3.1 Defining a new device configuration............................................................................................................... 21
4.3.2 Defining the interface to the control computer .............................................................................................. 23
4.3.3 Configuring the device and defining supporting points ................................................................................. 24
4.3.4 Using the teach dialog...................................................................................................................................... 31
5 Operation.............................................................................................................................................................. 33
5.1 Control device with arrow keys ........................................................................................................................ 33
5.2 Calibrate device................................................................................................................................................. 34
5.3 Remove the microplate from the shelf............................................................................................................ 35
5.4 Detach/dispose of microplate from gripper.................................................................................................... 36
5.5 Creating a method............................................................................................................................................ 37
6 Troubleshooting ................................................................................................................................................... 38
7 Maintenance and care.......................................................................................................................................... 41
7.1 Maintenance overview ..................................................................................................................................... 41
7.2 Cleaning the device........................................................................................................................................... 41
8 Transport and storage.......................................................................................................................................... 42

Table of contents CyBio Carry
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8.1 Transport........................................................................................................................................................... 42
8.2 Preparing the device for transport................................................................................................................... 42
8.3 Moving the device in the laboratory................................................................................................................ 44
8.4 Storage .............................................................................................................................................................. 44
9 Disposal ................................................................................................................................................................ 45
10 Specifications........................................................................................................................................................ 46
10.1 Technical data................................................................................................................................................... 46
11 Maintenance and wear parts ............................................................................................................................... 48

CyBio Carry Basic information
5
1 Basic information
1.1 About these assembly instructions
The assembly instructions describe the CyBioCarry plate transport system with the fol-
lowing models:
¡CyBio Carry 800
¡CyBio Carry 1200
¡CyBio Carry 1400
¡CyBio Carry 2000
The device is intended to be operated by qualified specialist personnel under observance
of these assembly instructions.
The assembly instructions are German original instructions or a translation of the origi-
nal instructions.
The assembly instructions inform about the device setup and operation and provide
qualified operating personnel with the necessary know-how for the safe handling of the
device.
Conventions Instructions for actions occurring in chronological order are numbered and combined
into action units.
Warnings are indicated by a warning triangle and a signal word. The type, source and
consequences of the hazard are stated together with notes on preventing the hazard.
Elements of the control and analysis program are indicated as follows:
¡Program terms are in bold (e.g., the System menu).
¡Menu items are separated by vertical lines (e.g., System|Device).
Symbols and signal words used
in this manual
The user manual uses the following symbols and signal words to indicate hazards or in-
structions. These warnings are always placed before an action.
WARNING
Indicates a potentially hazardous situation which can cause death or very serious (possi-
bly permanent) injury.
CAUTION
Indicates a potentially hazardous situation which can cause slight or minor injuries.
NOTICE
Provides information on potential material or environmental damage.

Basic information CyBio Carry
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1.2 Intended use
The CyBioCarry has been designed for automatic transportation of labware in SLAS for-
mat in chemical and biological laboratories. In the field of medicine and diagnostics its
use is limited to research.
The labware is usually microplates. The labware must comply with the ANSI/
SLAS1-2004 (Microplates - Footprint Dimensions) and ANSI/SLAS2-2004 (Mi-
croplates - Height Dimensions) standards:
¡The labware must be rectangular.
¡The labware must have certain minimum dimensions.
¡The labware must have a circumferential edge.
The solid plate edge must safely withstand the gripping force (25N).
The CyBioCarry transports microplates in landscape format between lab devices. The
maximum transport path in X-direction depends on the device model: 800 mm, 1200
mm, 1400 mm, or 2000 mm. The maximum deflection is 290mm in Y-direction and
245mm in Z-direction.
The device can briefly transport a weight of up to 500g.
For proper use, please observe the following:
¡The device must only be operated by qualified and trained personnel.
¡The device must only be used in accordance with this manual. This applies in partic-
ular to the adherence to the connection values, conditions of use and notes on the
maintenance, transport, and disposal.
¡The safety instructions in this manual must be observed.
It is not permissible
¡to operate this equipment in a medical laboratory,
¡to work with explosive substances in this device,
¡to operate this device in an explosive environment.
¡to smoke or use a naked flame at the installation location.
As regards the safe handling of dangerous substances (radioactive, infectious, toxic, cor-
rosive, combustible, and other hazardous substances), the owner/operator will be re-
sponsible in accordance with applicable laws and guidelines.
The same applies in terms of compliance with environmental protection rules (e. g. for
disposal of reagents and consumables).

CyBio Carry Safety
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2 Safety
2.1 General
For your own safety and to ensure error-free and safe operation of the device, please
read this chapter carefully before commissioning.
Screen Observe all safety instructions listed in these instructions, as well as all messages and in-
structions displayed by the control and analysis software on the monitor.
Besides the safety instructions in these instructions and the local safety regulations that
apply to the operation of the device, the general applicable regulations regarding acci-
dent prevention, occupational health and safety and environmental protection have to
be observed and complied with.
2.2 Safety labeling on the device
Warning and mandatory action labels have been attached to the device and must always
be observed.
Damaged or missing warning and mandatory action labels can cause incorrect actions
leading to personal injury or material damage. The labels must not be removed. Dam-
aged warning and mandatory action labels must be replaced immediately!
The following warning and mandatory action labels have been attached to the device:
Warning symbol Meaning Comment
Warning of a danger
point
Warning of mechanical hazard from
moving parts
Warning of crushing On the gripper: warning of hand injuries
from moving parts
Mandatory signs/
information sym-
bols
Meaning Comment
Wear eye protection On the gripper: wear eye protection
when working on the device.
For People's Republic of
China only
The device contains controlled sub-
stances. Analytik Jena GmbH guarantees
that these substances will not escape in
the next 25 years if the device is used
only as intended.

Safety CyBio Carry
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2.3 Danger zone
X
Z
Y
1
2
3
4
Fig.1 Movement range
1 Drive box with emergency stop button 2 Protective glass
3 Linear axis 4 Gripper tower
The gripper fingers can be moved in 3+1axes (X, Y, Z, gripper movement).
The device movements can endanger the operating personnel. Failure to observe warn-
ing information can result in crushing injuries, especially to hands. In addition, any inter-
ference with the device during operation can cause material damage.
The device is equipped with the following protective devices:
Emergency stop button At the drive box of the linear
axis
Stops all movement immedi-
ately
Protective glass At the gripper tower Stops all movement immedi-
ately
The transparent protective glass is mounted to the gripper tower. In the event of a colli-
sion with the protective glass, the device stops the drives immediately.
When the gripper fingers are extended, the device moves in X-direction at reduced
speed. This safety measure reduces the risk of injury.
Note the following:
¡Do not reach into the movement range of the device physically or with an object
during operation.
¡In an emergency, press the emergency stop button to stop the movement.

CyBio Carry Safety
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2.4 Safety instructions for operation
Requirements for the operating
personnel
The device must only be operated by qualified specialist personnel instructed in the use
of the device. The instruction must include conveying the content of these assembly in-
structions and the user manuals of the other system components. The assembly instruc-
tions must be accessible to the operating and service personnel at all times.
Obligations of the owner/oper-
ator
The operator is responsible for the selection of substances used in the process as well as
for their safe handling. This is particularly important for radioactive, infectious, poi-
sonous, corrosive, combustible, explosive and otherwise dangerous substances.
When handling hazardous substances, the locally applicable safety instructions and in-
structions in the safety data sheets from the manufacturers of the auxiliary and operat-
ing materials must be complied with.
Observe the following:
¡The operator is responsible for carrying out suitable decontamination should the de-
vice become contaminated externally or internally with dangerous substances.
¡Splashes, drops or larger liquid spillages should be removed using an absorbent ma-
terial such as cotton wool, laboratory wipes or cellulose.
¡For biological contamination, wipe the affected area with a suitable disinfectant,
such as an Incidin Plus solution. Then wipe the cleaned areas so that they are dry.
¡The only suitable cleaning method for the housing is wipe disinfection. If the disin-
fectant has a spray nozzle, apply disinfectant to a suitable cloth before using it on
the device.
Work particularly carefully and cleanly with infectious material because the device
cannot be decontaminated as a whole.
¡Before using a cleaning or decontamination procedure other than that prescribed by
the manufacturer, the user is required to check with the manufacturer that the in-
tended procedure will not damage the device. Safety labels attached to the device
must not have methanol applied.
Commissioning Incorrect installation can create serious hazards.
¡Only the Analytik Jena customer service or specialist personnel trained and autho-
rized by Analytik Jena is allowed to install and commission the device and its system
components.
¡The external power supply unit must be connected to a proper power outlet to en-
sure that the device (ground connector) meets the protection class I. Do not replace
the removable power supply unit with a different power supply unit (without protec-
tive ground conductor). Extensions of the supply cable are not permitted!
Operation The operator must make sure that the device and its safety equipment is in sound condi-
tion each time before starting up the device. This applies in particular after each modifi-
cation or extension of the device or its repair.
Observe the following:
¡The device may only be operated if all items of protective equipment (e.g. covers in
front of electronic components) are in place, properly installed and fully operational.
¡The sound condition of the protection and safety equipment must be checked regu-
larly. Any defects must be corrected as soon as they occur.
¡Protective and safety equipment must never be removed, modified or switched off
during operation.
¡Always ensure free access to the main switch and to the emergency shutdown
switches and locks during operation.
¡Keep all combustible materials away from the device.

Safety CyBio Carry
10
¡Ensure that no liquid enters the interior of the device, for example at cable connec-
tions. There is a danger of electric shock.
¡Modifications, conversions and extensions to the device are only permitted after
consultation with Analytik Jena. Unauthorized modifications can jeopardize the de-
vice’s operational safety and may lead to limitations regarding the warranty and ac-
cess to customer service.
2.5 Safety instructions – protection against explosion and fire
The device may not be operated in an explosive environment.
Smoking or handling open flames are prohibited in the room in which the device is oper-
ated!
2.6 Safety instructionsformaintenance and repair
The device is generally maintained by the customer service department of Analytik Jena
or specialist personnel trained and authorized by them.
Unauthorized maintenance can damage the device. For this reason, only the activities
described in the user manual in the "Maintenance and care" chapter may be performed
by the operator.
¡Work on the electronics may only be carried out by the customer service of Analytik
Jena and specially authorized technicians.
¡Only clean the exterior of the device with a slightly moistened, non-dripping cloth.
Use only water and, if required, customary surfactants.
¡Do not use organic solvents or abrasives to clean the device. Exercise caution when
decontaminating the device with disinfectants containing alcohol. The alcohol can
damage the safety labeling on the device.
¡Use only original spare parts, wear parts and consumables. They have been tested
and ensure safe operation. Glass part are wear parts and are not subject to the war-
ranty.
¡All protective equipment must be reinstalled and checked for proper function when
the maintenance or repair work is complete.
2.7 Safety instructions: Transport
Only transport the device and its components in the original packaging! Ensure that all
transport locks and safety devices have been fitted and that the device components are
fully emptied and decontaminated if applicable.

CyBio Carry Safety
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2.8 Behavior during emergencies
1
2
3
Fig.2 Emergency switch-off
1 Emergency stop button 2 On/Off switch
3 Drive box
If there is no immediate risk of injury, stop the device movement in a dangerous situa-
tion with the emergency stop button.
Alternatively, switch the device off using the on/off switch or pull the power plug out of
the power socket.

Technical description CyBio Carry
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3 Technical description
3.1 Setup and operating principle
The CyBioCarry transports labware (preferably microplates) in landscape format be-
tween lab devices. The gripper fingers can be moved in 3+1axes (X, Y, Z, gripper move-
ment). The device can briefly transport a weight of up to 500g.
Fig.3 CyBioCarry transports labware
The CyBioCarry is intended for integration in automated systems.
Fig.4 System with several lab devices by Analytik Jena
The device consists of the following two components:
¡CyBioCarryY/Z gripper tower
¡CyBioCarryX linear axis

CyBio Carry Technical description
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Gripper tower
1
2
3
4 5
6
7
Fig.5 CyBioCarryY/Z (gripper tower) setup, front and rear sides
1 Z-axis guide 2 Telescopic gripper finger
3 Gripper 4 Base with shelf for microplate
5 Control panel with arrow keys 6 Protective screen
7 LED with status indicator
The gripper tower can move along the linear axis in X-direction on the guide. During
operation, the rear of the gripper tower is turned towards the user. The gripper can
move up and down along the Z-guide on the gripper tower.
The telescopic fingers of the gripper consist of four finger elements each that are
mounted to the two gripper sides. The gripper fingers can be extended and retracted in
Y-direction.

Technical description CyBio Carry
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2 31
Fig.6 Gripper finger, attachment of the gripper jaw to the bottom finger element
1 Gripper finger 2 Bottom finger element
3 Gripper jaw
The gripper jaws are attached to the two bottom finger elements. The gripper jaws grip
the labware on the left and right at its solid edge. The gripper jaws have silicone mats
on the inside, which enables the gripper to lift and transport the labware without slip-
ping, even if the edge of the labware is very slim.
1
2
Fig.7 Side view, with gripper fingers extended
1 Gripper 2 Telescopic finger, extended

CyBio Carry Technical description
15
A second microplate can be stored and transported in the nest. The nest is equipped
with a sensor. The sensor issues an error message if a microplate is still in the nest when
the device is switched on.
The gripper tower is equipped with a protective glass made of acrylic glass. The user
can monitor the device movements through the transparent protective glass. If the user
touches or tilts the protective glass during operation, the device stops all movement im-
mediately.
Linear axis
1 2 3
4 5 6
Fig.8 CyBioCarryX (linear axis) setup
1 Interfaces 2 On/Off switch
3 Emergency stop button 4 Connection for external power supply
unit
5 Type plate 6 X-axis guide
The drive box with the on/off switch, the connection for the external power supply unit,
and the interfaces is located on the front end of the linear axis (→ "Connections and in-
terfaces" 16). In an emergency, the user can stop the device immediately with the
emergency stop button.
The maximum speed in X-direction is 500mm/s. When the gripper fingers are ex-
tended, the device moves at reduced speed. This safety measure reduces the risk of in-
jury.
Device models Analytik Jena offers four different models:
¡CyBio Carry 800
¡CyBio Carry 1200
¡CyBio Carry 1400
¡CyBio Carry 2000
The four models differ with regard to the length of the linear axis and therefore have
different ranges in X-direction: 800 mm, 1200 mm, 1400 mm, and 2000 mm. The
maximum deflection is 290mm in Y-direction and 245mm in Z-direction.
Indicator and control elements On the back of the gripper tower there is a control panel with the "Arrow up" and "Arrow
down" keys. The user can move the gripper and gripper finger to a desired position using
the arrow keys. The right LED on the control panel lights up when the arrow keys are ac-
tive. For safety reasons, the device cannot be controlled via the arrow keys during opera-
tion.

Technical description CyBio Carry
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Fig.9 Control panel with arrow keys and 2 LEDs
The status LED is located on the upper edge of the gripper tower. It is clearly visible
from all sides. The status LED indicates the following operating states:
Green, constant
light
The device is ready for operation. It can be operated via PC.
Green, flashing The device is working. It is completing a preset sequence.
Yellow A protective device has stopped the movement.
Red A device error has occurred.
Type plates The type plates are attached to the bottom of the gripper tower and the side of the lin-
ear axis. The type plates contain the following information:
¡Company name and complete address of the manufacturer
¡Name of the machine (type designation and trade name)
¡Model and serial number
¡Year of manufacture
3.2 Connections and interfaces
The connector panel is located on the front end of the linear axis.
Fig.10 Connections and interfaces

CyBio Carry Technical description
17
Name Function
On / Off On/Off switch
24V DC, 4A Connection for external power supply unit
(with specification of the operating voltage
and maximum current consumption)
ESTOP 1 E-STOP OUT, forwarding interface to an-
other device
ESTOP 2 E-STOP IN, connection for an opening switch
element (STOP function)
STOP Connection (2x 24VDC, 0.1mA) for an
opening switch element (STOP function)
BC RS232 interface for connecting a barcode
reader
ETH Ethernet port for network connection
COM 1 RS232 interface for connection to the con-
trol computer
COM 2 RS232 forwarding interface for connecting
additional lab devices using the same control
computer
External power supply unit The power supply unit is a wide range power supply unit. The voltage supply on the pri-
mary side comes from a power socket providing an AC voltage of 100to240V±10%
and a frequency of 50/60Hz.
On the secondary side, the power supply unit provides a DC voltage of 24V (max.
3.75A).
1 2
Fig.11 External power supply unit
1 Input 2 Output
3.3 Labware requirements
The labware is usually microplates. The labware must comply with the ANSI/
SLAS1-2004 (Microplates - Footprint Dimensions) and ANSI/SLAS2-2004 (Mi-
croplates - Height Dimensions) standards:
¡The labware must be rectangular.
¡The labware must meet the minimum width and minimum depth requirements.
¡The labware must have a circumferential edge.

Technical description CyBio Carry
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The solid plate edge must safely withstand the gripping force (25N).
Fig.12 Labware dimensions
Minimum length (l) 127.76mm±0.5mm
Minimum depth (d) 85.48mm±0.5 mm
Typical height (h + h‘)
(h‘ = height of the plate edge)
14.35mm±0.76mm
The device transports the labware in landscape format.
3.4 Scope of delivery
The following components are included in the delivery:
¡CyBioCarry plate transport system, consisting of:
– CyBioCarryX (linear axis) variant
– CyBioCarryY/Z (gripper tower)
¡External power supply unit and connecting cable, RS232 cable
¡Packaging box with transport locks
The following technical documentation is included in the scope of delivery:
¡Declaration of incorporation
¡Assembly instructions
¡Software documentation (CyBio Composer)

CyBio Carry Installation and commissioning
19
4 Installation and commissioning
4.1 Installation conditions
4.1.1 Ambient conditions
Observe the following location requirements:
¡This laboratory device is designed for inside use.
¡Do not use the device in explosion-hazard environments.
¡Do not locate the device near sources of electromagnetic interference.
¡Place the device on a stable, horizontal surface.
¡Avoid mechanical shocks and vibrations.
¡The installation site must be free of drafts, dust and caustic fumes.
¡Do not use the device in wet and damp environments. Keep the device surface clean
and dry.
¡Avoid direct sunlight and radiation from heaters onto the device. If necessary, pro-
vide air conditioning.
¡Allow the device to acclimatize after transport and storage. Otherwise, condensed
air moisture could damage the sensitive electronics during commissioning.
¡Position the device so that the emergency stop button and the on/off switch are al-
ways easily accessible.
The following requirements are placed on the climatic conditions in the operating room:
¡Operating temperature: +15to+35°C
¡Humidity during operation: ≤75% at +35°C, non-condensing
4.1.2 Spatial requirements
The required space depends on all components that make up the system.
The CyBioCarry plate transport system has the following dimensions (depending on the
model used):
Width 735 to 2375mm (→ "Technical data" 46)
Height 530mm
Depth ¡140mm
¡400mm (with protective glass and maximally extended gripper
fingers)
Provide sufficient space for a control computer, monitor, and other PC accessories.
4.1.3 Power supply
WARNING
Danger due to electrical voltage
¡Only connect the device to a properly grounded socket which complies with the volt-
age specified in these instructions (→ "Technical data" 46).
¡Do not use an adapter in the feeder.

Installation and commissioning CyBio Carry
20
The device operates on single-phase alternating current. The installation of the electri-
cal equipment in the laboratory must comply with the DIN VDE 0100 standard. At the
connection point, an electrical current in accordance with the standard IEC 60038 must
be available.
4.2 Commissioning
The device may only be set up and installed by the customer service department of Ana-
lytik Jena or by persons authorized by Analytik Jena.
Observe the safety instructions in these instructions when installing and commissioning
the device (→ "Safety" 7). Compliance with the safety instructions is a requirement for
the trouble-free installation and operation of your system. Observe all warnings and in-
structions that are attached to the device or displayed by the control software.
To ensure trouble-free operation, make sure that the installation conditions are ob-
served.
Initial commissioning includes the following:
¡Unpacking and positioning the device
¡Connecting the cables (→ "Connections and interfaces" 16)
¡Software installation (basic installation settings) and device configuration
¡Instruction in the operation
The device is controlled by means of an external PC and the CyBio Composer software.
The software controls all devices in a system, such as the Liquid Handling & Automation
products of Analytik Jena and the devices of other manufacturers. The software includes
a plug-in for the plate transport system.
Unpacking the device The device should be delivered directly to the final device location by a transport com-
pany. Ensure that a person responsible for positioning the device is present when the
device is delivered.
A special label for transport inspection is attached to the front of the transport box. The
special label contains a shock indicator.
Fig.13 Front of the transport box with special label
Shock indicator ¡The label indicates whether the product was sub-
jected to severe shocks and vibration during trans-
port.
¡The glass tube in the indicator field turns red if a
defined acceleration value was exceeded during
transport.
¡When accepting the delivery, check the special label to verify that the transport con-
ditions were observed.
¡Do not open the transport packaging if the indicator shows a defect. Inform Analytik
Jena immediately.