GeneAll GENTi 32 User manual

Ver. 1.0
GENTi Automatic Extraction Equipment
User Manual (Instruction for Use)
Automated Nucleic Acid Extraction System

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CONTENTS
Introduction ...........................................................................................................................3
1. Product intended Use.......................................................................................................3
2. Product description.......................................................................................................... 3
3. Product characteristics .....................................................................................................3
4. Product specifications .....................................................................................................4
GENTi Automated Nucleic Acid Extraction System requirements ..............................................4
Product Components............................................................................................................... 5
WEEE ....................................................................................................................................5
Precautions before using the product .......................................................................................6
Unpacking andInstalling process ............................................................................................ 7
1. How to unpack the “GENTi”...........................................................................................7
2. How to install the “GENTi”............................................................................................. 8
3. Hardware overview.......................................................................................................... 9
4. The switch mechanism of GENTi ....................................................................................... 9
User Interface .................................................................................................................... 10
1. User interface for home screen....................................................................................... 10
2. Instruction in Plate set-up .............................................................................................. 11
3. Instruction in Strip set-up............................................................................................... 12
4. Implementation of GENTi ............................................................................................... 13
5. Camera systemon GENTi ................................................................................................ 15
6. Warning code for GENTi................................................................................................. 15
7. Error code for GENTi .................................................................................................... 16
8. Regular maintenance ..................................................................................................... 17
9. More information about GENTi........................................................................................ 18
Troubleshooting ................................................................................................................... 18
Warranty ............................................................................................................................. 19
Constraint on Warranty ..................................................................................................... 20
Symbols............................................................................................................................... 20
This user manual introduces into the detail of “GENTi Automatic Extraction Equipment”and protocols through the

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contents. It also contains the specification of the “GENTi Automatic Extraction Equipment”for further information.
Before using the “GENTi ”, it is a recommendation of the user to read this equipment user manual carefully and
understand specifically on Safety Information.
Introduction
1. Product intended use
The “GENTi 32”is intended to be used as a combination with ”GENTi Extraction kits”that provide automated extraction
of nucleic acid from samples.
Diagnostic results would be obtained by using the nucleic acids extracted with this equipment and it must be interpreted
in conjunction with other clinical, laboratory or other experiment data.
Extracted nucleic acid through “GENTi system”can be used for various downstream application such as molecular
diagnostics, PCR, sequencing and so on.
The automated steps performed by “GENTi Automatic Extraction Equipment”include:
Sample lysis and binding of nucleic acids to magnetic beads
Washing of nucleic acids
Elution of nucleic acids
2. Product Description
The “GENTi Automatic Extraction Equipment” is automatic nucleic acid extraction equipment based on magnetic bead
separation technology with integrated magnetic rods. The equipment adapted two configurations (96-well plate and strip
tube) for maximize flexibility of sample load. The equipment extracts nucleic acid from various sample through lysis,
binding, washing and elution steps. Intuitive interface allows users simple operation by touching just one button.
3. Product Characteristics
System control or test can be implemented with the touch monitor (No PC or tablet needed)
UV lamp exists on the equipment to aid in sanitizing the equipment
Easy-to-use system (application of optimal protocols for DNA, RNA extraction)
The equipment has a preprogrammed protocol for nucleic acid purification
The equipment gives the high efficiency of nucleic acids purification to use
The user will shorten he hands-on-time by using “GENTi 32”product.
Max. 32 samples can be run in a single run

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4. Specifications
Average processing time: approx. 5-30 minutes (it is various depends on how many products/samples are set
on the equipment )
Number of samples: samples can be set up to 32
Standard configuration: ~200 ㎕of sample volume
Weight: 33.9 kg (74lb)
Dimensions: 365(W) x 390(D)x 435(H)mm (14.4 (W) x 15.4(D) x 17.1(H) inch)
System Requirements for “GENTi Automatic Extraction Equipment”
To use this equipment, system requirements are applied in general condition at room temperature 25 °C (77 °F).
unless there is other specific notice or indications.
When user needs to store for a long period of time, it must be packed in a vacuum.
If the equipment has not been used for a long time, it must be used after inspection.
Regulation of Voltage
Please, make sure that the range of voltage is as follow:
Input Voltage: 220 - 240V
Power requirements: 50/60㎐, 2A
Environmental requirements
Temperature
Operation
Storage
10-40°C
10-50°C
Humidity
Operation
Storage
10-80% RH, Non-condensed
10-80% RH, Non-condensed
Maximum altitude 2000m
The equipment should be operated indoors. For, indoor use only.

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Product Components
Please check and inspect the package carefully to make sure that all GENTi equipment components are included prior to
use.
GENTi Automatic Extraction Equipment
Other components
Figure 1. Components of GENTi Automatic Extraction Equipment
GENTI Autometic Extraction Equipment: 1 ea
Power cable: 1 ea
8-strip (for the test mode/calibration use only): 2 ea
96-well plate (for the test mode/calibration use only): 2 ea
WEEE
-The components below, they shall be disposed and/or replaced based on the WEEE (Waste Electrical and
Electronic Equipment Directive) standard.
-UV lamp
-LED lamp
-Power cable
-Touch monitor
-External case
-Front door

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Precautions before using the product
Please read the precautions for correct use of the product.
This IVD equipment complies with the EMC test requirements and described in IEC61326 and the safety
requirements of IEC 61010.
This product complies with the European Directives described in 2006/95/EC and 2004/108/EC for CE marking.
Do NOT use the GENTi Automatic Extraction Equipment with other voltages out of the range specified
(220~240V± 10%, 50/60㎐) on the equipment.
The equipment must be installed to allow easy connection of the power line to the power inlet.
DO NOT use the GENTi Automatic Extraction Equipment with a damaged power supply or loose socket.
Please KEEP the equipment on a flattened surface and provide minimum of a feet at every side of the
equipment for air circulation.
A strong impact on the equipment may causes severe damage and thus malfunction.
DO NOT connects multiple equipments into a single wall outlet. The load may cause an overload and fire.
GENTi Extraction Equipment vibrates when it is operated. DO NOT place any devices and/or supplements on
the equipment that might be damaged by vibration.
DO NOT place any devices that produce vibration or heat besides “GENTi 32”.
DO NOT install and/or store the equipment in dusty place
DO NOT install and/or store the equipment near heat sources.
DO NOT install and/or store the equipment near water or moist place before/while user use
DO NOT attempt to change or modify the equipment without GeneAll’s permission.
DO NOT try to connect the power plug with wet hands.
GNETi Automatic Extraction Equipment is closed system thus it is exclusively optimized to use in combination
with the “GENTi Extraction reagents. DO NOT attempt to use any other brand of the kit or reagents.
Please make sure that pre-filled 96- well and check the plate if it is set in correct position on the plate tray.
DO NOT disassemble the equipment. It may cause fire, electrical shock and malfunction and the warranty
shall NOT be guaranteed if disassembled.
DO NOT use this equipment with any purpose other than its intended use.
DO NOT pour any liquid on the GENTi equipment.
DO NOT place other vibration sensitive equipments near equipment.
The front door must be CLOSED during the operation of equipment.
Please DO NOT operate the equipment in the place near flammable gases or liquids.

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Dispose the UV bulb in accordance with country, federal, state and local regulations and laws since it contains
mercury.
Please disconnect the power before cleaning or performing routine maintenance.
There is a possibility to be exposed by UV rays due to the UV lamp of equipment. DO NOT turn on the UV
lamp unless completely close the front door.
Please make ensure that magnetic rod covers and plates have been securely inserted in their correct positions
and orientation. Failure may result in damage to the equipment.
Before using the operation system, please check the magnetic rod position to prevent the damage to the
equipment
Use the switch in order to shut off the power supply safely
DO NOT operate the system if malfunction is expected.
As the touch panel is made with LCD screen, please use the touch panel slightly and smoothly with soft
finger touch and the LCD screen will response back from user’s activation order. Instead of using Sharp tools-
such as Knife, Nail or pen, not finger; it may cause damages on the LCD screen.
This equipment is intended for use with human-derived samples. Please use appropriate personal protective
apparatus (i.e.-gloves, safety goggles, lab coat, etc.) for handling and disposing of biological-hazardous
materials safely.
Keep hands clear out from equipment platform as it moves in and out of the equipment.
Keep the surface of equipment clean once you use.
When there is any SIGN OF FIRE (smoke, burning smell etc) while operating the equipment or stand-by
mode, Please STOP the operation IMMEDIATELY, and DISCONNECT the power cable from the unit and
contact to Customer Service or Manufacturer immediately
The equipment shall be sterilized with UV lamp at all time. DO NOT look or touch UV lamp directly. It may
damage to eyes or skin.
If the equipment is stained by reagents, samples or dirts after use, please disinfect the equipment with 70%
ethanol and turn off the equipment after the stain is completely cleared out.
The Plate tray will be heated automatically during operation of the equipment. It may cause the skin burn
easily if any part of the body got touched with plate tray. DO NOT touch the plate tray directly with any part of
the body if the equipment is activated at any circumstance while using.
Please discard the plate and magnetic rod cover into the biological-hazard disposable container after use.
If any part of the body; especially when the eye is exposed to reagents, please keep the eye(s) open and flush
out with eye wash or tap water and go to the hospital immediately.
Dispose of the equipment in accordance with national, federal, state and local regulations and laws.
Unpacking and Installation
1. Unpacking the GENTi Automatic Extraction Equipment
The GENTi is operated by step motor which is movable. Therefore, the equipment and supplements are fixed and
delivered to prevent equipment damages.

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WARNING
Risk of personal injury and material damage
Please ensure that the fixture must be removed before connecting the power.
1) Please cut and remove all of tapes or straps around the box to open the shipping box
2) Before using, or after open the box, please check whether GENTi Automatic Extraction Equipment is intact or not. If
there is any damage on equipment or unusable supplements, please DO NOT use defected equipment and contact
Technical service team to get better/further assistance. The power supply should be switched off unless the equipment
is operating the test.
3) Please remove the fixture to use the equipment.
WARNING
Risk of personal injury and material damage
Please ensure that the main power must be switched off before release the fixture.
Figure 2. Adjust the horizontality by turning/balancing the rubber feet (Bottom view)
1. Please maintain the level by using rubber feet as shown in Figure 2.
2. How to install the GENTi
The GENTi is intended for indoor use only.
Before installing the GENTi 32, please install the equipment in a location that meets the following criteria:
Locate the equipment on a sturdy, horizon level surface or place area.
Avoid dusty areas or places that might cause damage the equipment.
Please DO NOT place the equipment near or where the surface generates heats constantly.
Try to locate away from direct sunlight and avoid the equipment away from heat sources.
Please put all vibration and electrical interference sources away from installed area to prevent safety.
DO NOT connect a large number of powers from other equipment into an outlet. It may cause the major

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electrical fire while using.
DO NOT leave any thing anything at front side of the equipment to not to disturb the operation.
DO NOT use the equipment near to flammable gases or liquids for safety.
Locate a distance at least minimum clearance 10cm at the sides and rear of GENTi.
3. Hardware Overview
External features
Front view
Rear view
Figure 3. External feature of GENTi Automatic Extraction Equipment
Internal features
Figure 4. Internal features of GENTi Automatic Extraction Equipment
4. Switching on the GENTi
After connecting the equipment to a power outlet, user may switch on the equipment. The power switch is located on
the Front of the equipment. (Figure. 5)

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Figure 5. Power switch
The LED power switch can be used during the operation of experiment in case user wants to check the extraction
process, the switch is located next to touch monitor of front side (on the upper right side).
Figure 6. LED Power switch
Magnetic Rod will automatically moves to its original position when it is initialized.
User Interface for GENTi
1. User interface for home screen
The start-up on screen page is showed up on the touch monitor and initializes the sensors after turn the equipment on.
Figure 7. The Booting image on the screen window.
If everything is completed without any problems, the main home screen will be appeared as below.