HumaPen MS9673 User manual

1
MS9673 HumaPen LUXURA®HD
INSULIN DELIVERY DEVICE
INSTRUCTIONS FOR USE
For use only with Lilly 3mL insulin cartridges (100 units/mL). Do not use other brands
of insulin cartridges.
The colour of your HumaPen LUXURA®HD is Rainforest Green.
For Single Patient Use Only
www.lilly.ca
HumaPen LUXURA
®
HD Pen Parts
Pen Needle
(sold separately)
Cartridge
HolderLilly 3 mL Insulin Cartridge
(sold separately)
Screw Dose
Window
Dose
Knob Inner CapPaper Tab
Pen
CapRubber Seal *Cartridge Plunger
*The colour of
your Cartridge
Plunger may
differ
Pen
Body Injection
Button
Outer
CapNeedle
HumaPen LUXURA HD is designed to enable you to reliably deliver an accurate dose
of your insulin in an easy to use manner. You can give yourself multiple doses from
one Lilly 3 mL insulin cartridge (100 units/mL). You can inject from 0.5 to 30 units of
insulin from a Lilly 3 mL insulin cartridge in each injection. You can dial your dose one
half (1/2) unit at a time. If you dial the wrong dose,you can correct the dose without
wasting any insulin.
Read these instructions completely and follow the directions carefully before
using the pen. Failure to follow the instructions may result in the wrong insulin
dose being delivered.
DO NOT SHARE YOUR PEN OR NEEDLES AS THIS MAY RISK TRANSMISSION
OF INFECTIOUS AGENTS.
If any of the parts of your Pen appear broken or damaged, DO NOT USE. Contact
your healthcare professional or call Lilly at 1-888-545-5972 for a replacement
pen.
HumaPen LUXURA HD is not recommended for the blind or visually impaired
without the assistance of a sighted individual trained to use it.

2
Always carry a spare source of insulin that you are trained on how to inject and
could immediately use in case your pen is lost or damaged.
1INSERT THE INSULIN CARTRIDGE
Important Notes
Your healthcare professional has prescribed the type of insulin best for you.
Any changes in insulin should be made only under medical supervision.
HumaPen LUXURA HD is for use only with Lilly 3 mL insulin cartridges.
Do not use other brands of insulin cartridges.
Read and follow the instructions provided in your Lilly 3mL insulin cartridge
Consumer Information Leaflet.
Before each injection, read the cartridge label and be sure the pen contains the
correct Lilly 3mL insulin cartridge.
The colour of the pen is not intended to indicate insulin type.
The numbers on the cartridge holder give an estimate of the amount of insulin
remaining in the cartridge. Do not use these numbers for measuring an insulin
dose.
For more information on HumaPen LUXURA HD and Lilly insulin, please contact
your healthcare professional or Lilly at 1-888-545-5972 or visit our website at
www.lilly.ca.
Frequently Asked Questions about Inserting the Insulin Cartridge
1. Why doesn’t the screw move out when there is no cartridge in the pen?
The screw may not move out when you push the injection button unless there is a
cartridge in the pen. This feature of the pen allows you to easily push the screw into
the pen body when replacing a cartridge. Once a cartridge is inserted, the screw will
move out when the injection button is pushed.
2. What should I do if I can’t attach the cartridge holder to the pen body?
Check that the insulin cartridge is fully inserted into the cartridge holder. Then carefully
line up the cartridge holder with the pen body and screw together until secure.
2PRIME THE PEN (BEFORE EVERY INJECTION)
Important Notes
HumaPen LUXURA HD is recommended for use with BD Pen Needles.
The directions regarding needle handling are not intended to replace local,
healthcare professional or institutional policies.
Do not store your pen with the needle attached. Use a new needle for each
injection. This will help ensure sterility. It will also help prevent leakage of insulin,
keep out air bubbles, and reduce needle clogs.

3
Frequently Asked Questions about Priming
1. Why is it important to prime before every injection?
If you do NOT prime, you may get the wrong insulin dose. Priming helps to ensure
that the pen and needle are working properly. Once the pen is properly primed, insulin
will flow from the needle. You may need to prime several times before you see insulin
at the tip of the needle.
2. Why can it take several attempts to prime when a new cartridge is inserted?
There may be a gap between the screw and the cartridge plunger. Repeating the
priming steps will move the screw out to touch the cartridge plunger. Once the end of
the screw pushes the cartridge plunger out, insulin will flow from the needle.
Before Priming After Priming
*Cartridge
Plunger Gap Screw No Gap Between Screw and Cartridge Plunger
.*The colour of your Cartridge Plunger may differ.
-Repeat the priming steps until insulin is seen at the tip of the needle.
-If you are still unable to see insulin flow from the needle, go to Question 3.
3. Why should I prime until I see insulin at the tip of the needle?
Priming moves the screw into contact with the cartridge plunger and gets the air out of
the cartridge.
-You may see insulin on the tip of the needle when you first attach it. This only
shows that the needle is attached and not clogged. You must still prime the pen.
-You may also see no insulin at all when you are priming the pen. This may be
because the screw is moving forward to close a gap between the screw and the
cartridge plunger.
-Insulin will flow only when the pen is properly primed.
-If the injection button is hard to push, the needle may be clogged. Attach a new
needle. Repeat the priming steps until insulin is seen at the tip of the needle.
If you are still unable to see insulin flow from the needle, do NOT use the pen.
Contact your healthcare professional or Lilly at 1-888-545-5972 for assistance or to
obtain a replacement.
4. What should I do if I have an air bubble in the cartridge?
Priming your pen will remove air bubbles. Point the pen up, and tap the cartridge
gently with your finger so any air bubbles can collect near the top. Repeat the priming

4
steps until insulin is seen at the tip of the needle. A small air bubble may remain in the
cartridge after completion of the priming steps. If you have properly primed the pen,
this small air bubble will not affect your insulin dose.
3INJECT THE DOSE
Important Notes
You must PUSH the injection button straight down for the dose to be delivered.
You will NOT receive your insulin by turning the dose knob.
Do not attempt to change the dose while injecting.
Frequently Asked Questions about Injecting
1. Why is it difficult to push the injection button when I try to inject?
-Your needle may be clogged.Try attaching a new needle, and then prime the
pen.
-Pushing the injection button down quickly may make the button harder to push.
Pushing the button more slowly may make it easier.
- Using a larger diameter needle will make it easier to push the injection button
during injection. See your healthcare professional to determine which needle is
best for you.
-Your injection button may become harder to push if the inside of your pen gets
dirty with insulin, food, drink or other materials. Following the CARE AND
STORAGE instructions below should prevent this.
If none of the above steps resolves the problem, your pen may need to be replaced.
2. Why doesn’t the dose knob go to zero when I inject my dose?
This can happen if the insulin cartridge does not have enough insulin left in it for your
entire dose. The number in the dose window is the amount you did NOT receive. To
get the rest of your dose, remove the needle, change the insulin cartridge, attach a
new needle and prime the pen. Then complete your dose by dialing the amount that
you did NOT receive and inject only this amount.
3. Why is insulin leaking from the needle after I finish my dose?
You may have removed the needle from your skin too quickly; remember to push and
hold the injection button and slowly count to 5 before removing the needle. Make
sure you see a 0 in the dose window to confirm you received the complete dose.
CARE AND STORAGE
Remove the needle after every use. Do not store the pen with the needle attached.
Keep your HumaPen LUXURA HD, Lilly 3 mL insulin cartridges, and needles out of
the reach and sight of children.

5
Keep the pen away from moisture, dust, extreme hot or cold temperatures, and
direct sunlight.
Do not store the pen in a refrigerator.
Wipe the pen cap, pen body and case with a damp cloth to clean them.
Do not use alcohol, hydrogen peroxide or bleach on the pen body or dose window.
Also, do not cover in liquid or apply lubrication such as oil, as this could damage
the pen.
Refer to the insulin cartridge Consumer Information Leaflet for complete insulin
storage instructions.
REPLACEMENT
Your HumaPen LUXURA HD has been designed to be used for up to 3 years
after first use. Record the date your pen was first used here: __/__/__. Go
directly to a pharmacy to get a new HumaPen LUXURA HD when your pen has
been used for 3 years.
If you have any questions or concerns with your HumaPen LUXURA HD, contact
your healthcare professional or Lilly at 1-888-545-5972 for assistance.
USE AS DIRECTED
HumaPen LUXURA HD should only be used as described in this manual. The
manufacturer will not be responsible for any problems with the device if these
instructions are not followed. Failure to follow the instructions may result in
breakage of the pen and the wrong insulin dose being delivered.

6
Getting Ready
Wash your hands and make sure you have the following items before beginning:
HumaPen LUXURA®HD
Lilly 3mL Insulin Cartridge
New Pen Needle
Alcohol Swab
HumaPen LUXURA HD
INSULIN DELIVERY DEVICE
Pen Needle
(sold separately)
Rubber
Seal *Cartridge Plunger Screw Dose Window Dose Knob Inner CapPaper Tab
Pen
CapCartridge Holder
Lilly 3 mL
Insulin Cartridge
(sold separately)
Pen
Body Injection Button Outer CapNeedle
*The colour of your Cartridge Plunger may differ
HumaPen LUXURA
®
HD Pen Parts
1
INSERT THE INSULIN CARTRIDGE
Pull Off Pen Cap Insert Cartridge Push Screw Back
Unscrew Cartridge
Holder
Insert small end of
Lilly 3 mL insulin cartridge
into the cartridge holder.

The screw may be in or
out when you get the
pen.
If the screw is out, use
the cartridge plunger to
push the screw back.
Note:
Check the insulin cartridge
to make sure it is not
cracked or broken and
your insulin is not expired
before inserting the insulin
cartridge.
Note:
If you push the injection
button without a cartridge in
the cartridge holder the
screw will not move
forward.
A B C

7
Attach Cartridge Holder
Inspect Insulin
For Cloudy Insulin Only
Roll the pen gently 10
times,
Push the cartridge holder
and pen body straight
together. Screw the pen
body onto the cartridge
holder until it is secure.
Be sure to check your
insulin for:
Type
Appearance
Wipe the small rubber seal
on the end of the cartridge
with an alcohol swab.
and invert the pen 10
times. The insulin should
look evenly mixed.
Caution: If the
cartridge holder is not
completely attached, the
screw may not move and
you may not get your full
dose.
D E F

8
2
PRIME THE PEN (BEFORE EVERY INJECTION)
Caution: If you do NOT prime, you may get the wrong insulin dose.
Remove Paper Tab Remove Needle Cap Dial 2 Units
Attach Needle
Screw needle straight
onto the cartridge holder.
Pull off the outer cap.
Save the outer cap to
remove the needle after
your injection.
Pull off the inner cap and
throw it away.
Tap
Cartridge
Point pen
up.
Tap
cartridge
to collect
air
bubbles
at the top
for
removal.
A B C

9
Prime The Pen
If No InsulinIs Seen, Repeat
Priming
Push injection button
and hold for 5 seconds.
Look for insulin at the
tip of the needle.
Dial
2 units.
Tap
cartridge.
Caution: Several
attempts to prime may
be needed the first time
a cartridge is used. If
no insulin flows after
several attempts the
needle may be clogged
and should be
replaced.
Push
injection
button
and
look for
insulin at
the
needle
tip.
D E

10
3 INJECT THE DOSE
Dial Your Dose
Turn dose knob to
your desired dose.
Example: 5½ units
shown in the
drawing above.
If you dial too many
units, you can
correct the dose by
dialing backwards.
The dose knob
clicks as you turn it.
DO NOT dial your
dose by counting
clicks because you
may dial the wrong
dose.
Inject
Y
our Dose
Insert the needle as directed by
your healthcare professional.
Place your thumb on the
injection button then slowly
and firmly push the button until
it stops moving.
Continue to hold the
button for 5 seconds,
then remove the needle
from your skin.
Check to make sure you see a
0 in the dose window to confirm
you received the complete
dose.
Note:
It is possible to set a dose larger than the
amount of insulin left in the cartridge.
At the end of an injection, the number in
the dose window should be 0. If it is not,
this is the amount of insulin you did NOT
receive.Remember this number.
Remove the needle and the empty
cartridge.
Insert a new cartridge as shown in 1,
attach a new needle, and prime the pen as
shown in 2.
Complete your dose by injecting only the
amount you did not receive.
If you do not think you received your full
dose, do not take another dose. Call your
healthcare professional or Lilly at 1-888-
545-5972 for assistance.
A B
5 seconds

11
Replace Needle Outer Cap
Remove The Needle
Carefully replace the outer
cap as instructed by your
healthcare professional.

Remove the capped needle by twisting it off.
Put used needles in a sharps container or a
hard plastic container with a secure lid. Do not
throw needles directly into your household
trash.
Do not recycle the filled sharps container.
Ask your healthcare provider about options to
dispose of the sharps container properly. You
can also check the Canadian Diabetes
Association website at www.diabetes.ca for
information on sharps disposal.
The directions regarding needle handling are
not intended to replace local, healthcare
provider ofinstitutional policies.
Replace Pen Cap
Note:
To prevent air from entering
the cartridge, do not store
the pen with a needle
attached.
C D
If you have any questions or concerns with your HumaPen LUXURA HD or
require further assistance, contact your healthcare professional or Lilly at 1-888-
545-5972. Distributed by:
Eli Lilly Canada Inc.
3650 Danforth Avenue
Toronto, Ontario
M1N 2E8
Manufactured by:
Eli Lilly and Company
Pharmaceutical Delivery Systems
Lilly Corporate Center
Indianapolis, IN 46285, USA

12
Authorized Representative in the EU:
Eli Lilly and Company Ltd.
Erl Wood Manor, Sunninghill Road, Windlesham, Surrey
GU20 6PH UK CE
0344
HumaPen LUXURA HD meets the current dose accuracy and functional
requirements of ISO 11608-1:2000 with Lilly 3 mL cartridges.
HumaPen LUXURA HD is a trademark owned by or licensed to Eli Lilly and Company,
its subsidiaries or affiliates.
HPLUXHD-0002-CA-IFU-20170907
Copyright © 2007, 2017Eli Lilly and Company. All rights reserved.
Document Revision Date: September 07, 2017