Mindray BC-5380 User manual

BC-5380Auto Hematology Analyzer
Service Manual

I
Copyright
© 2008 Shenzhen Mindray Bio-medical Electronics Co., Ltd. All rights Reserved.
For this Service Manual, the issued Date is 2008-12 (Version: 1.0).
Intellectual Property Statement
SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (hereinafter called Mindray)
owns the intellectual property rights to this Mindray product and this manual. This manual may
refer to information protected by copyrights or patents and does not convey any license under
the patent rights of Mindray, nor the rights of others. Mindray does not assume any liability
arising out of any infringements of patents or other rights of third parties.
Mindray intends to maintain the contents of this manual as confidential information. Disclosure
of the information in this manual in any manner whatsoever without the written permission of
Mindray is strictly forbidden.
Release, amendment, reproduction, distribution, rent, adaption and translation of this manual
in any manner whatsoever without the written permission of Mindray is strictly forbidden.
,are the registered trademarks or trademarks owned by Mindray in China and
other countries. All other trademarks that appear in this manual are used only for editorial
purposes without the intention of improperly using them. They are the property of their
respective owners.
Responsibility on the Manufacturer Party
Contents of this manual are subject to changes without prior notice.
All information contained in this manual is believed to be correct. Mindray shall not be liable for
errors contained herein nor for incidental or consequential damages in connection with the
furnishing, performance, or use of this manual.
Mindray is responsible for safety, reliability and performance of this product only in the
condition that:
all installation operations, expansions, changes, modifications and repairs of this product
are conducted by Mindray authorized personnel;

II
the electrical installation of the relevant room complies with the applicable national and
local requirements;
the product is used in accordance with the instructions for use.
zThis equipment must be operated by skilled/trained medical professionals.
zIt is important for the hospital or organization that employs this equipment
to carry out a reasonable service/maintenance plan. Neglect of this may
result in machine breakdown or injury of human health.
zBe sure to operate the analyzer under the situation specified in this manual;
otherwise, the analyzer will not work normally and the analysis results will
be unreliable, which would damage the analyzer components and cause
personal injury.

III
Warranty
THIS WARRANTY IS EXCLUSIVE AND IS IN LIEU OF ALL OTHER WARRANTIES,
EXPRESSED OR IMPLIED, INCLUDING WARRANTIES OF MERCHANTABILITY OR
FITNESS FOR ANY PARTICULAR PURPOSE.
Exemptions
Mindray's obligation or liability under this warranty does not include any transportation or other
charges or liability for direct, indirect or consequential damages or delay resulting from the
improper use or application of the product or the use of parts or accessories not approved by
Mindray or repairs by people other than Mindray authorized personnel.
This warranty shall not extend to:
any Mindray product which has been subjected to misuse, negligence or accident;
any Mindray product from which Mindray's original serial number tag or product
identification markings have been altered or removed;
any product of any other manufacturer.
Return Policy
Return Procedure
In the event that it becomes necessary to return this product or part of this product to Mindray,
the following procedure should be followed:
1. Obtain return authorization: Contact the Mindray Service Department and obtain a
Customer Service Authorization (Mindray) number. The Mindray number must appear on
the outside of the shipping container. Returned shipments will not be accepted if the
Mindray number is not clearly visible. Please provide the model number, serial number,
and a brief description of the reason for return;
2. Freight policy: The customer is responsible for freight charges when this product is
shipped to Mindray for service (this includes customs charges);
3. Return address: Please send the part(s) or equipment to the address offered by Customer
Service department.

IV
Company Contact
Manufacturer: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
Address: Mindray Building, Keji 12th Road South, Hi-tech Industrial Park,
Nanshan,ShenZhen 518057, P.R.China,
Phone: [phone] 26582888
Fax: [phone] 26582500

1
Table of Contents
1Using This Manual............................................................................................... 1-1
1.1 Introduction............................................................................................................ 1-1
1.2 Who Should Read This Manual............................................................................. 1-2
1.3 How to Find Information ........................................................................................ 1-3
1.4 Conventions Used in This Manual......................................................................... 1-4
1.5 Symbols................................................................................................................. 1-5
2System Structure................................................................................................. 2-1
2.1 Introduction............................................................................................................ 2-1
2.2 Fluidic System ....................................................................................................... 2-2
2.3 Hardware System .................................................................................................. 2-3
2.4 Main Structure ....................................................................................................... 2-4
2.5 Software structure ............................................................................................... 2-11
2.5.1 Menu structure ....................................................................................... 2-11
2.5.2 Passwords.............................................................................................. 2-31
3Instrument Installation and Software Upgrade................................................. 3-1
3.1 Preparations .......................................................................................................... 3-1
3.1.1 Purpose .................................................................................................... 3-1
3.1.2 Tools ......................................................................................................... 3-1
3.1.3 Accessories .............................................................................................. 3-1
3.2 Installation Requirements ...................................................................................... 3-2
3.2.1 Space Requirements ................................................................................ 3-2
3.2.2 Power Requirements................................................................................ 3-2
3.2.3 Environment Requirements...................................................................... 3-2
3.2.4 PC Configuration Requirements .............................................................. 3-3
3.3 Package Checking and Unpacking ....................................................................... 3-7
3.3.1 Checks before unpacking......................................................................... 3-7
3.3.2 Unpacking the main unit........................................................................... 3-7
3.3.3 Checking packing list................................................................................ 3-9
3.4 Removal and Installation ..................................................................................... 3-10
3.5 Connections......................................................................................................... 3-23
3.6 Start-up ................................................................................................................ 3-27
3.6.1 Inspection before Startup ....................................................................... 3-27
3.7 Setup and Adjustment ......................................................................................... 3-35
3.8 Testing Other Functions....................................................................................... 3-41
3.9 Confirming Gain................................................................................................... 3-42
3.10 Calibration and Performance Test ....................................................................... 3-47
3.11 Software upgrade ................................................................................................ 3-53
4Fluidic System ..................................................................................................... 4-1
4.1 Introduction of Fluidic Parts ................................................................................... 4-1
4.1.1 Piercing needle......................................................................................... 4-1
4.1.2 Probe Wipe............................................................................................... 4-1

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2
4.1.3 Pumps ...................................................................................................... 4-1
4.1.4 Syringes ................................................................................................... 4-1
4.1.5 Valves ....................................................................................................... 4-1
4.1.6 Baths ........................................................................................................ 4-1
4.1.7 Volumetric tube......................................................................................... 4-2
4.1.8 Filters........................................................................................................ 4-2
4.2 Fluidic System ....................................................................................................... 4-3
4.2.1 Reagent volume required......................................................................... 4-3
4.2.2 Fluidic System Drawing............................................................................ 4-5
4.2.3 WBC Measurement Procedures .............................................................. 4-6
4.2.4 RBC/PLT Measurement Procedures........................................................ 4-6
4.2.5 HGB Measurement Procedures ............................................................... 4-7
4.3 Sequence of Whole Blood CBC+DIFF Measurement........................................... 4-8
4.3.1 Sampling and dispensing procedures...................................................... 4-8
4.3.2 DIFF Channel ......................................................................................... 4-10
4.3.3 WBC/HGB Channel................................................................................ 4-13
4.3.4 RBC/PLT Channel .................................................................................. 4-15
4.3.5 Sequence of Predilute Mode CBC+DIFF Measurement........................ 4-18
4.3.6 Sequence of CBC Measurement ........................................................... 4-18
5Hardware System ................................................................................................ 5-1
5.1 Mother board ......................................................................................................... 5-3
5.1.1 Introduction............................................................................................... 5-3
5.1.2 Board Composition................................................................................... 5-3
5.1.3 Adjustment and Test Points.................................................................... 5-26
5.1.4 Removal ................................................................................................. 5-28
5.1.5 Troubleshooting...................................................................................... 5-30
5.2 Data board........................................................................................................... 5-32
5.2.1 Introduction............................................................................................. 5-32
5.2.2 Board composition.................................................................................. 5-32
5.2.3 Adjustment and Test Points.................................................................... 5-45
5.2.4 Disassembly and assembly method....................................................... 5-49
5.2.5 Troubleshooting...................................................................................... 5-51
5.3 Drive board .......................................................................................................... 5-59
5.3.1 Introduction............................................................................................. 5-59
5.3.2 Board composition.................................................................................. 5-59
5.3.3 Adjustment and Test Points.................................................................... 5-75
5.3.4 Disassembly and assembly method....................................................... 5-78
5.3.5 Troubleshooting...................................................................................... 5-80
5.4 Autoloader board ................................................................................................. 5-99
5.4.1 Introduction............................................................................................. 5-99
5.4.2 Board Composition................................................................................. 5-99
5.4.3 Adjustment and Test Points.................................................................. 5-109
5.4.4 Disassembly and assembly method..................................................... 5-110
5.4.5 Troubleshooting.................................................................................... 5-112
5.5 Power board ...................................................................................................... 5-117
5.5.1 Introduction........................................................................................... 5-117
5.5.2 Board Composition............................................................................... 5-117
5.5.3 Adjustment and Test Points.................................................................. 5-122
5.5.4 Replacement and Connection.............................................................. 5-124
5.5.5 Troubleshooting.................................................................................... 5-127
5.6 Volumetric and pressure detecting board.......................................................... 5-129
5.6.1 Introduction........................................................................................... 5-129
5.6.2 Board Composition............................................................................... 5-129
5.6.3 Disassembly and assembly method..................................................... 5-132
5.6.4 Troubleshooting.................................................................................... 5-134

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3
5.7 Liquid-level detecting board .............................................................................. 5-140
5.7.1 Introduction........................................................................................... 5-140
5.7.2 Board composition................................................................................ 5-140
5.7.3 Replacement and Connection.............................................................. 5-143
5.7.4 Troubleshooting.................................................................................... 5-145
5.8 Laser Control Board .......................................................................................... 5-148
5.8.1 Introduction........................................................................................... 5-148
5.8.2 Board Composition............................................................................... 5-148
5.8.3 Adjustment and Test Points.................................................................. 5-150
5.8.4 Assembly and disassembly.................................................................. 5-151
5.8.5 Troubleshooting.................................................................................... 5-151
5.9 Pre-amplification board...................................................................................... 5-154
5.9.1 Introduction........................................................................................... 5-154
5.9.2 Board Composition............................................................................... 5-154
5.9.3 Adjustment and Test Points.................................................................. 5-158
5.9.4 Disassembly and assembly.................................................................. 5-158
5.9.5 Troubleshooting.................................................................................... 5-158
5.10 Indicator Board .................................................................................................. 5-160
5.10.1 Introduction........................................................................................... 5-160
5.10.2 Board Composition............................................................................... 5-160
5.10.3 Disassembly and assembly method..................................................... 5-161
5.10.4 Troubleshooting.................................................................................... 5-162
5.11 Key Board .......................................................................................................... 5-163
5.11.1 Introduction........................................................................................... 5-163
5.11.2 Board Composition............................................................................... 5-163
5.11.3 Disassembly and assembly method..................................................... 5-164
5.11.4 Troubleshooting.................................................................................... 5-165
6Maintenance......................................................................................................... 6-1
6.1 Maintenance Modules and the Corresponding Settings ....................................... 6-1
6.2 General.................................................................................................................. 6-3
6.3 Disassembling the Panels ..................................................................................... 6-4
6.3.1 Removing the left door ............................................................................. 6-4
6.3.2 Removing the right door........................................................................... 6-5
6.3.3 Removing the top cover ........................................................................... 6-6
6.3.4 Removing the back panel......................................................................... 6-7
6.3.5 Removing the front door........................................................................... 6-8
6.3.6 Removing the front cover assembly......................................................... 6-9
6.4 Replacing the Valves, Pumps and Syringes........................................................ 6-11
6.4.1 Replacing valves .................................................................................... 6-13
6.4.2 Replacing the Pressure Chamber .......................................................... 6-15
6.4.3 Replacing the Vacuum Chamber ........................................................... 6-17
6.4.4 Replacing the Syringe Assembly............................................................ 6-18
6.4.5 Replacing the Waste Pump.................................................................... 6-24
6.5 Replacing the Bath/Aperture Assembly............................................................... 6-26
6.6 Replacing the Sampling Module and Adjusting Position ..................................... 6-29
6.6.1 Replacing the Sample Probe and Wipe ................................................. 6-29
6.6.2 Replacing the Optical Sensor................................................................. 6-31
6.6.3 Removing the Sampling Module ............................................................ 6-33
6.7 Maintaining and Replacing the DIFF Reaction Bath ........................................... 6-37
6.8 Autoloader Assembly (Closed-Tube)................................................................... 6-39
6.8.1 Removing and replacing the closed-tube sample compartment assembly
6-39
6.8.2 Removing and replacing the detection switches of the sample transport unit

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4
6-45
6.8.3 Replacing the sample transport unit....................................................... 6-46
6.9 Mix mechanism.................................................................................................... 6-58
6.10 Adjustment........................................................................................................... 6-66
6.10.1 Adjusting Sample Probe Position........................................................... 6-66
6.10.2 Adjusting Pincher Position ..................................................................... 6-73
7Optical System..................................................................................................... 7-1
7.1 Optical System Adjustment and Troubleshooting.................................................. 7-1
7.2 Removing and Installing Optical System Assemblies............................................ 7-3
7.2.1 Laser driver board .................................................................................... 7-3
7.2.2 Front light assembly ................................................................................. 7-4
7.2.3 Flow cell assembly ................................................................................... 7-5
7.2.4 Rear light collimator assembly ................................................................. 7-7
7.2.5 Beam splitter assembly ............................................................................ 7-7
7.2.6 Rear light collector assembly ................................................................... 7-8
7.2.7 Rear light detector assembly.................................................................. 7-10
7.3 Adjustment........................................................................................................... 7-12
7.3.1 Coarse adjustment ................................................................................. 7-12
7.3.2 Preparation before fine tuning................................................................ 7-18
7.3.3 Fine tuning.............................................................................................. 7-19
7.3.4 Gain setup .............................................................................................. 7-24
7.4 Troubleshooting ................................................................................................... 7-27
7.4.1 Laser spot-deviation............................................................................... 7-27
7.4.2 Flow cell clog.......................................................................................... 7-27
7.4.3 Dirty flow cell .......................................................................................... 7-28
8Troubleshooting .................................................................................................. 8-1
8.1 Error code and information.................................................................................... 8-1
8.2 Errors indicated by error messages ...................................................................... 8-9
8.2.1 Pressure errors......................................................................................... 8-9
8.2.2 Reagent errors ......................................................................................... 8-9
8.2.3 Hardware errors ..................................................................................... 8-10
8.2.4 Measurement errors............................................................................... 8-10
8.2.5 Temperature errors................................................................................. 8-12
8.2.6 Scattergram errors ................................................................................. 8-13
9Appendixes ......................................................................................................... A-1
A. Accessories ...........................................................................................................A-1
B. List of Wearing Parts .............................................................................................B-1
C. Fluidic diagram ..................................................................................................... C-1
D. Pump and Valve Function Table ........................................................................... D-1
E. Tubing....................................................................................................................E-1
F. Method to identify cross network cable and direct-connected network cable ....... F-1