MSI G4101-01 User manual

G4101-01
MS-S337
Server System
User Guide

2Contents
Revision
V1.0, 2023/12
Contents
Regulatory Notices....................................................................................................... 4
Safety Information........................................................................................................ 6
System Specifications .................................................................................................. 7
System Overview .......................................................................................................... 8
System LED Indicators............................................................................................... 10
Motherboard Overview............................................................................................... 11
Motherboard Storage................................................................................................. 12
Motherboard Expansion Slots................................................................................... 14
Motherboard Connectors .......................................................................................... 15
Power Connectors ................................................................................................ 15
Cooling Connectors .............................................................................................. 17
WATER_LEAKING1: CPU Pump Water Leak Detection Connector..................... 18
USB Connectors ................................................................................................... 19
Other Connectors ................................................................................................. 21
Motherboard Jumpers............................................................................................... 30
Onboard LEDs............................................................................................................. 31
BMC_HB_LED: BMC Heartbeat LED.................................................................... 31
SEG_LED1~4: Port 80 Debug LEDs...................................................................... 32
Getting Started............................................................................................................ 33
Necessary Tools ................................................................................................... 33
Safety Precautions................................................................................................ 33
System Setup.............................................................................................................. 34
Drive Bay ..................................................................................................................... 34
Installing 2.5" HDD/ SSD ...................................................................................... 34

3
Contents
System Cover.............................................................................................................. 35
Removing System Cover....................................................................................... 35
CPU & Cooler.............................................................................................................. 36
Installing CPU & Heatsink.................................................................................... 37
Installing Liquid Cooling Module.......................................................................... 40
Memory ....................................................................................................................... 43
Recommended Memory Population..................................................................... 44
Installing Memory Modules.................................................................................. 45
M.2 M Key.................................................................................................................... 46
Installing an M.2 SSD ........................................................................................... 46
GPGPU Card................................................................................................................ 47
Installing GPGPU Card ......................................................................................... 47
Cable Routing ............................................................................................................. 50
Power Cables ....................................................................................................... 50
I2C Cables............................................................................................................. 51
Cables for Front & Rear I/O ................................................................................. 52
Storage Cables ..................................................................................................... 53

4Regulatory Notices
Regulatory Notices
WEEE Statement
Under the European Union (“EU”) Directive on Waste Electrical and
Electronic Equipment, Directive 2012/19/EU, products of “electrical and
electronic equipment” cannot be discarded as municipal waste anymore
and manufacturers of covered electronic equipment will be obligated to
take back such products at the end of their useful life.
Chemical Substances Information
In compliance with chemical substances regulations, such as the EU REACH
Regulation (Regulation EC No. 1907/2006 of the European Parliament and the
Council), MSI provides the information of chemical substances in products at:
https://csr.msi.com/global/index
CE Conformity
Hereby, Micro-Star International CO., LTD declares that this device is in
compliance with the essential safety requirements and other relevant
provisions set out in the European Directive.
FCC-A Radio Frequency Interference Statement
This equipment has been tested and found to comply with the limits
for a Class A digital device, pursuant to Part 15 of the FCC Rules.
These limits are designed to provide reasonable protection against
harmful interference when the equipment is operated in a commercial
environment. This equipment generates, uses and can radiate radio
frequency energy and, if not installed and used in accordance with the instruction
manual, may cause harmful interference to radio communications. Operation of this
equipment in a residential area is likely to cause harmful interference, in which case
the user will be required to correct the interference at his own expense.
Notice 1
The changes or modifications not expressly approved by the party responsible for
compliance could void the user’s authority to operate the equipment.
Notice 2
Shielded interface cables and AC power cord, if any, must be used in order to comply
with the emission limits.
This device complies with Part 15 of the FCC Rules. Operation is subject to the
following two conditions:
∙This device may not cause harmful interference, and
∙This device must accept any interference received, including interference that may
cause undesired operation.

5
Regulatory Notices
Battery Information
Please take special precautions if this product comes with a battery.
∙Danger of explosion if battery is incorrectly replaced. Replace only with the same or
equivalent type recommended by the manufacturer.
∙Avoid disposal of a battery into fire or a hot oven, or mechanically crushing or
cutting of a battery, which can result in an explosion.
∙Avoid leaving a battery in an extremely high temperature or extremely low air
pressure environment that can result in an explosion or the leakage of flammable
liquid or gas.
∙Do not ingest battery. If the coin/button cell battery is swallowed, it can cause
severe internal burns and can lead to death. Keep new and used batteries away
from children.
European Union:
Batteries, battery packs, and accumulators should not be disposed of as
unsorted household waste. Please use the public collection system to
return, recycle, or treat them in compliance with the local regulations.
BSMI:
廢電池請回收
For better environmental protection, waste batteries should be collected
separately for recycling or special disposal.
California, USA:
The button cell battery may contain perchlorate material and requires
special handling when recycled or disposed of in California.
For further information please visit:
http://www.dtsc.ca.gov/hazardouswaste/perchlorate/
Copyright and Trademarks Notice
Copyright © Micro-Star Int’l Co., Ltd. All rights reserved. The MSI logo used is
a registered trademark of Micro-Star Int’l Co., Ltd. All other marks and names
mentioned may be trademarks of their respective owners. No warranty as to accuracy
or completeness is expressed or implied. MSI reserves the right to make changes to
this document without prior notice.
Technical Support
If a problem arises with your product and no solution can be obtained from the user’s
manual, please contact your place of purchase or local distributor. Alternatively,
please visit https://eps.msi.com/support for further guidance.

6Safety Information
Safety Information
∙Always read the safety instructions carefully.
∙Keep this User’s Manual for future reference.
∙Keep this equipment away from humidity.
∙Lay this equipment on a reliable flat surface before setting it up.
∙The openings on the enclosure are for air convection hence protects the equipment
from overheating. Do not cover the openings.
∙Make sure the voltage of the power source and adjust properly before connecting
the equipment to the power inlet.
∙Place the power cord such a way that people can not step on it. Do not place
anything over the power cord.
∙Always unplug the power cord before inserting any add-on card or module.
∙All cautions and warnings on the equipment should be noted.
∙Never pour any liquid into the opening that could damage or cause electrical shock.
∙If any of the following situations arises, get the equipment checked by service
personnel:
∙The power cord or plug is damaged.
∙Liquid has penetrated into the equipment.
∙The equipment has been exposed to moisture.
∙The equipment does not work well or you can not get it work according to User’s
Manual.
∙The equipment has dropped and damaged.
∙The equipment has obvious sign of breakage.
∙Do not leave this equipment in an environment unconditioned, storage
temperature above 60°C (140°F), it may damage the equipment.

7
System Specifications
System Specifications
Model G4101-01
Form Factor 4U
Dimensions 17.2”W (447.9mm) x 6.9”H (176mm) x 32.6”D (827.3mm)
Processor
∙1 x AMD® EPYC™ 9004 Series Processors
-Processor socket SP5 (LGA 6096)
-Cores up to 128C
-TDP 500W
Memory
∙12 x DDR5 DIMM slots
-Supports 12-Channel DDR5
-Supports RDIMM/ 3DS RDIMM, up to 128GB, 4800MT/s (1DPC), ECC
Internal Storage 2 x M.2 M-Key (PCIe 3.0 x4/x2, 2280/ 22110)
Drive Bays ∙12 x 2.5” Hybrid hot-swap drive bays
-Supports U.2 NVMe 4.0/ SAS/ SATA signals
Expansion Slots
∙6 x PCIe 5.0/4.0 x16 Full-height/Full-length (FH/FL) slots
-4 x PCIe 5.0 x16 slots for triple slot GPGPU
-2 x PCIe 4.0 x16 slots (PCIe 4.0 x8/x16 signal from CPU)
Security ∙TPM 2.0
∙Case intrusion switch
Server
Management
∙Aspeed AST2600 IPMI 2.0 with iKVM support
∙1 x GbE RJ45 port (Mgmt.)
-Realtek® RTL8211FD-CG
Cooling ∙1 x Passive CPU heatsink @280W (Optional)
∙1 x CPU liquid cooling @500W
Environment
∙Operating Temperature: 0°C ~ 35°C
∙Non-operating Temperature: -20°C ~ 70°C
∙Non-operating Relative Humidity: 5% ~ 85% (non-condensing)
Accessory 1 x Slide Rail (Optional)
Certifications CE, FCC (Class A)

8System Overview
System Overview
12 x 2.5” U.2 NVMe 4.0
Hybrid Hot-Swap Drive Bays or 12 x 2.5” SAS/ SATA
Hybrid Hot-S wap Drive Bays
33
44
55
22
11
88
55
99
77
66

9
System Overview
11
M.2 Activity LED
!
System Status LED
1
MLAN LEDs
22System Power Button/ LED
33UID LED Button
(or BMC Reset Button, configured using jumper: JUID_SEL1)
44System Reset Button
55USB 3.2 Gen 1 Type-A Port
This connector is provided for USB peripheral devices. (Speed up to 5 Gbps)
66UID Button
77VGA Port
88
GbE RJ45 Port (for Mgmt.)
The standard RJ45 LAN jack is provided for connection to the Local Area
Network (LAN). You can connect a network cable to it.
LINK/ACT
LED
SPEED
LED
LED Status Description
Link/ Activity
LED
Off No link
Green Linked
Blinking Data activity
Speed LED
Off 10 Mbps
Orange 100 Mbps
Green 1 Gbps
99RJ45 Serial Console Port

10 System LED Indicators
System LED Indicators
System Power Button/ LED
System Reset Button
UID Button/ LED
!
System Status LED
M.2 Activity LED
1
MLAN LED
LED LED State Description
Power LED Blue System is on
Blinking System is sleeping
Off System is off
System is on ACPI S4, S5 state
UID LED Blue Identify active via command or button
Off No identification
!
System Status LED Green BMC initialization
Red System has failed
Off System is running/ normal operation
1
MLAN LED Green LAN link is established
Blinking LAN activity is occurring
Off LAN link is not established
M.2 Activity LED Amber Storage drive in use
Off No storage drive activity

11
Motherboard Overview
Motherboard Overview
CPU0
CPU0_DIMM_A1 CPU0_DIMM_B1 CPU0_DIMM_C1 CPU0_DIMM_D1 CPU0_DIMM_E1 CPU0_DIMM_F1 CPU0_DIMM_L1 CPU0_DIMM_K1 CPU0_DIMM_J1 CPU0_DIMM_I1 CPU0_DIMM_H1 CPU0_DIMM_G1
SYS_FAN1
SYS_FAN3
SYS_FAN4
SYS_FAN5
SYS_FAN2
JREAR1
JFUSB1
CPU_FAN2
JPWR_MB6
JPWR_MB7
JPWR_MB8
JPWR_MB9
JPWR_MB4
JPWR_MB5
JPWR_MB1
JPWR_MB2
JPWR_MB3
JPSU1
JIPMB1
J95X8
JFP1
LAN1
JCOM1
JUID
M2_1
JMPCIE4 JMPCIE3
JMPCIE5 JMPCIE6
M2_2
JVGA
JTPM1
CPU_FAN1
SYS_FAN6
SYS_FAN7
SYS_FAN8
JMCIO5
JMCIO6
JMCIO7
JMCIO8 JMCIO1JMCIO2
JMCIO3
JMCIO4
JSATA_NVME_SW1
BP_I2C_1
JCHASSIS1
DOM1
PCIE_SLOT1 PCIE_SLOT2 PCIE_SLOT3 PCIE_SLOT4
PCIE_SLOT5
PCIE_SLOT6
1
1
2
2
3
3
4
45
5
6
6
7
7
8
9
9
10
WATER_LEAKING1
11
8
10
BAT1
JSPI_MUX1
JBMC_DBG1
JUID_SEL1
JRTC_CLR1
JSEL_BMC1
JBTN1
JRST1
SYS_FAN1
SYS_FAN3
SYS_FAN4
SYS_FAN5
SYS_FAN2
SYS_FAN6
SYS_FAN7
SYS_FAN8
1
2
3
4
5
6
7
8
SYS_FAN1
SYS_FAN3
SYS_FAN4
SYS_FAN5
SYS_FAN2
SYS_FAN6
SYS_FAN7
SYS_FAN8
1
2
3
4
5
6
7
8
11
PDB_I2C_1
BMC_HB_LED
SEG_LED4
SEG_LED3
SEG_LED2
SEG_LED1

12 Motherboard Storage
Motherboard Storage
Slot Speed
JMCIO1~2 PCIe 5.0 x8 32GT/s (Default)
SATA 3.0 6Gb/s
JMCIO3~8 PCIe 5.0 x8 32GT/s
M2_1 PCIe 3.0 x4 8GT/s
M2_2 PCIe 3.0 x2 8GT/s
M2_1~2: M.2 Slots (M Key, PCIe 3.0, 22110/ 2280)
The M.2 slot supports solid-state drive (SSD). For Installation procedure, please refer
to “System Setup > M.2 M Key".
JMCIO8 JMCIO2
JMCIO1
JMCIO4
JMCIO3
JMCIO5
JMCIO6
JMCIO7
M2_2
M2_1

13
Motherboard Storage
JMCIO1~8: MCIO 8i Connectors
These connectors serve as MCIO interface ports, supporting both SATA and NVMe
devices.
JMCIO1~8
B37
A37
B1
A1
A1 GND B1 GND
A2 SSD_RX+ B2 SSD_TX+
A3 SSD_RX- B3 SSD_TX-
A4 GND B4 GND
A5 SSD_RX+ B5 SSD_TX+
A6 SSD_RX- B6 SSD_TX-
A7 GND B7 GND
A8 NC B8 SMB_PEHPCPU_LV3_SCL
A9 FM_SMB_CPU_ALERT_N B9 SMB_PEHPCPU_LV3_SDA
A10 GND B10 GND
A11 CLK_100M_SSD_DP B11 RST_PCIE_CPU_PERST_N
A12 CLK_100M_SSD_DN B12 FM_PCIE_SSD_PRSNT_N
A13 GND B13 GND
A14 SSD_RX+ B14 SSD_TX+
A15 SSD_RX- B15 SSD_TX-
A16 GND B16 GND
A17 SSD_RX+ B17 SSD_TX+
A18 SSD_RX- B18 SSD_TX-
A19 GND B19 GND
A20 SSD_RX+ B20 SSD_TX+
A21 SSD_RX- B21 SSD_TX-
A22 GND B22 GND
A23 SSD_RX+ B23 SSD_TX+
A24 SSD_RX- B24 SSD_TX-
A25 GND B25 GND
A26 NC B26 SMB_PEHPCPU_LV3_SCL
A27 FM_SMB_CPU_ALERT_N B27 SMB_PEHPCPU_LV3_SDA
A28 GND B28 GND
A29 CLK_100M_SSD_DP B29 RST_PCIE_CPU_PESET_N
A30 CLK_100M_SSD_DN B30 FM_PCIE_SSD_PRSNT_N
A31 GND B31 GND
A32 SSD_RX+ B32 SSD_TX+
A33 SSD_RX- B33 SSD_TX-
A34 GND B34 GND
A35 SSD_RX+ B35 SSD_TX+
A36 SSD_RX- B36 SSD_TX-
A37 GND B37 GND

14 Motherboard Expansion Slots
Motherboard Expansion Slots
PCIE_SLOT6: PCIe 4.0 x 16 slot (Gen 4 x8/x16 signal)
PCIE_SLOT5: PCIe 4.0 x 16 slot (Gen 4 x8/x16 signal)
PCIE_SLOT4: PCIe 5.0 x 16 slot (Gen 5 x16 signal)
PCIE_SLOT3: PCIe 5.0 x 16 slot (Gen 5 x16 signal)
PCIE_SLOT2: PCIe 5.0 x 16 slot (Gen 5 x16 signal)
PCIE_SLOT1: PCIe 5.0 x 16 slot (Gen 5 x16 signal)
PCIE_SLOT1~6: PCIe Expansion Slots
The PCI Express(Peripheral Component Interconnect Express) slots support PCIe
interface expansion cards.
⚠
Important
When adding or removing expansion cards, make sure that you unplug the power
supply first. Meanwhile, read the documentation for the expansion card to configure
any necessary hardware or software settings for the expansion card, such as jumpers,
switches or BIOS configuration.

15
Motherboard Connectors
Motherboard Connectors
Power Connectors
JPWR_MB1~4: 12V Power Connectors (for MB PWR)
8
5
14
JPWR_MB1~4
1 GND 5 P12V
2 GND 6 P12V
3 GND 7 P12V
4 GND 8 P12V
JPWR_MB5: 12V Power Connector (for BP PWR)
5
84
1
JPWR_MB5
1 GND 5 P12V
2 GND 6 P12V_AUX
3 GND 7 P12V_AUX
4 GND 8 P12V_STBY
JPWR_MB9
JPWR_MB8
JPWR_MB6
JPWR_MB7
JPWR_MB5
JPWR_MB4
JPWR_MB1
JPWR_MB2
JPWR_MB3

16 Motherboard Connectors
JPWR_MB6, JPWR_MB8: Power Connectors (5V)
JPWR_MB6
JPWR_MB8
1
2 4
31 GND 3 P5V
2 GND 4 P5V
JPWR_MB7, JPWR_MB9: Power Connectors (3V)
JPWR_MB7
JPWR_MB9
1
2 4
31 GND 3 P3V
2 GND 4 P3V
JPWR_HDD1: HDD/SATA Power Connector (on PDB)
1
4
85
JPWR_HDD1
1 GND 5 P12V
2 GND 6 P12V
3 GND 7 P12V
4 GND 8 P12V
JPWR_HDD1
Power Delivery Board (PDB)
⚠
Important
Make sure that all power connectors are securely connected to the power supply to
ensure stable operation of the motherboard.

17
Motherboard Connectors
Cooling Connectors
SYS_FAN1~8: System/CPU Fan Power Connectors
The fan power connectors support system/ CPU cooling fans.
SYS_FAN1~8
1 2
65
1 FAN_TACH 2 P12V
3 PWM 4 P12V
5 GND 6 GND
CPU_FAN1~2: CPU Pump Power Connectors
The fan power connectors support CPU pump.
1
4
CPU_FAN1~2
1 GND 3 FAN_TACH
2P12V 4FAN_PWM
SYS_FAN1
SYS_FAN2
SYS_FAN3
SYS_FAN4
SYS_FAN5
SYS_FAN7
SYS_FAN8
SYS_FAN6
CPU_FAN2
CPU_FAN1

18 Motherboard Connectors
WATER_LEAKING1: CPU Pump Water Leak Detection Connector
This connector is for detecting water leaks in the CPU water cooling pump. If a leak is
detected, the system will automatically shut down for protection.
1
4
WATER_LEAKING1
1 P5V_AUX
2Water_Leaking
3GND
4GND

19
Motherboard Connectors
USB Connectors
DOM1: USB 3.2 Gen 1 Type-A Connector
The USB (Universal Serial Bus) port is for attaching USB devices such as
keyboard, mouse, or other USB-compatible devices. It supports up to
5 Gbps data transfer rate.
JREAR1
JFUSB1
DOM1
DOM1

20 Motherboard Connectors
JREAR1, JFUSB1: USB 3.2 Port Box Headers
This port is backward-compatible with USB 2.0 devices and supports data transfer
rate up to 5 Gbps.
JREAR1
1
10 11
20
JFUSB1
JREAR1
1P5V_AUX_USB_BP2 11 HUB_SSD2P_ESD_DP
2HUB_SSRX1N_ESD 12 HUB_SSD2N_ESD_DN
3HUB_SSRX1P_ESD 13 GND
4GND 14 HUB_SSTX2_C_ESD_TXP
5HUB_SSTX1_C_ESD_TXN 15 HUB_SSTX2_C_ESD_TXN
6HUB_SSTX1_C_ESD_TXP 16 GND
7GND 17 HUB_SSRX2P_ESD
8HUB_SSD1N_ESD_DN 18 HUB_SSRX2N_ESD
9HUB_SSD1P_ESD_DP 19 P5V_AUX_USB_BP3
10 NC 20 No Pin
JFUSB1
1P5V_AUX_USB_BP4 11 HUB_SSD4P_ESD_DP
2HUB_SSRX3N_ESD_RXN 12 HUB_SSD4N_ESD_DN
3HUB_SSRX3P_ESD_RXP 13 GND
4GND 14 HUB_SSTX4_C_TXP_ESD_TXP
5HUB_SSTX3_C_TXN_ESD_TXN 15 HUB_SSTX4_C_TXP_ESD_TXP
6HUB_SSTX3_C_TXP_ESD_TXP 16 GND
7GND 17 HUB_SSRX4P_ESD_RXP
8HUB_SSD3N_ESD_DN 18 HUB_SSRX4N_ESD_RXN
9HUB_SSD3P_ESD_DP 19 P5V_AUX_USB_BP5
10 NC 20 No Pin