MSI MS-S322 User manual

S2205 (2U24)
MS-S322
Server System
User Guide

2Contents
Revision
V1.2, 2023/09
Contents
Regulatory Notices....................................................................................................... 4
Safety Information........................................................................................................ 6
System Specifications .................................................................................................. 7
System Overview .......................................................................................................... 8
System LED Indicators............................................................................................... 11
Motherboard Overview............................................................................................... 12
Motherboard Connectors .......................................................................................... 13
Power Connectors ................................................................................................ 13
Storage Connectors.............................................................................................. 15
FPC Connectors.................................................................................................... 19
Box Headers ......................................................................................................... 21
Motherboard Jumpers............................................................................................... 26
Motherboard Expansion Slots................................................................................... 27
Onboard LEDs............................................................................................................. 28
Getting Started............................................................................................................ 29
Necessary Tools ................................................................................................... 29
Safety Precautions................................................................................................ 29
System Setup.............................................................................................................. 30
Drive Bay ..................................................................................................................... 30
Installing 2.5" HDD/ SSD ...................................................................................... 30
System Cover.............................................................................................................. 31
Removing System Cover....................................................................................... 31
CPU & Heatsink.......................................................................................................... 32
Installing CPU & Heatsink.................................................................................... 33

3
Contents
Memory ....................................................................................................................... 36
Recommended Memory Population..................................................................... 37
Installing Memory Modules.................................................................................. 39
M.2 M Key.................................................................................................................... 40
Installing M.2 M Key ............................................................................................. 40
PCIe Add-in Card........................................................................................................ 41
Installing PCIe Add-in Card.................................................................................. 41
Installing Riser Card Assembly............................................................................ 42
System Fan ................................................................................................................. 43
Installing 2U Fan................................................................................................... 43
Installing 2U Fan Cage ......................................................................................... 44
Air Duct........................................................................................................................ 45
Installing Air Duct................................................................................................. 45
Power Supply Unit (PSU) ........................................................................................... 46
Installing PSU....................................................................................................... 46
Cable Routing ............................................................................................................. 47
Slide Rail ..................................................................................................................... 52
Disassembling Slide Rail...................................................................................... 52
Installing Inner Rail to System............................................................................. 53
Retracting Outer Rail Bracket.............................................................................. 54
Attaching Outer Rail Bracket to Rack Frame ...................................................... 54
Installing System into Rack.................................................................................. 55
Detaching Outer Rail Bracket from Rack Frame................................................. 56
Detaching Inner Rail from System....................................................................... 56

4Regulatory Notices
Regulatory Notices
WEEE Statement
Under the European Union (“EU”) Directive on Waste Electrical and
Electronic Equipment, Directive 2012/19/EU, products of “electrical and
electronic equipment” cannot be discarded as municipal waste anymore
and manufacturers of covered electronic equipment will be obligated to
take back such products at the end of their useful life.
Chemical Substances Information
In compliance with chemical substances regulations, such as the EU REACH
Regulation (Regulation EC No. 1907/2006 of the European Parliament and the
Council), MSI provides the information of chemical substances in products at:
https://csr.msi.com/global/index
CE Conformity
Hereby, Micro-Star International CO., LTD declares that this device is in
compliance with the essential safety requirements and other relevant
provisions set out in the European Directive.
FCC-A Radio Frequency Interference Statement
This equipment has been tested and found to comply with the limits
for a Class A digital device, pursuant to Part 15 of the FCC Rules.
These limits are designed to provide reasonable protection against
harmful interference when the equipment is operated in a commercial
environment. This equipment generates, uses and can radiate radio
frequency energy and, if not installed and used in accordance with the instruction
manual, may cause harmful interference to radio communications. Operation of this
equipment in a residential area is likely to cause harmful interference, in which case
the user will be required to correct the interference at his own expense.
Notice 1
The changes or modifications not expressly approved by the party responsible for
compliance could void the user’s authority to operate the equipment.
Notice 2
Shielded interface cables and AC power cord, if any, must be used in order to comply
with the emission limits.
This device complies with Part 15 of the FCC Rules. Operation is subject to the
following two conditions:
∙This device may not cause harmful interference, and
∙This device must accept any interference received, including interference that may
cause undesired operation.

5
Regulatory Notices
Battery Information
Please take special precautions if this product comes with a battery.
∙Danger of explosion if battery is incorrectly replaced. Replace only with the same or
equivalent type recommended by the manufacturer.
∙Avoid disposal of a battery into fire or a hot oven, or mechanically crushing or
cutting of a battery, which can result in an explosion.
∙Avoid leaving a battery in an extremely high temperature or extremely low air
pressure environment that can result in an explosion or the leakage of flammable
liquid or gas.
∙Do not ingest battery. If the coin/button cell battery is swallowed, it can cause
severe internal burns and can lead to death. Keep new and used batteries away
from children.
European Union:
Batteries, battery packs, and accumulators should not be disposed of as
unsorted household waste. Please use the public collection system to
return, recycle, or treat them in compliance with the local regulations.
BSMI:
廢電池請回收
For better environmental protection, waste batteries should be collected
separately for recycling or special disposal.
California, USA:
The button cell battery may contain perchlorate material and requires
special handling when recycled or disposed of in California.
For further information please visit:
http://www.dtsc.ca.gov/hazardouswaste/perchlorate/
Copyright and Trademarks Notice
Copyright © Micro-Star Int’l Co., Ltd. All rights reserved. The MSI logo used is
a registered trademark of Micro-Star Int’l Co., Ltd. All other marks and names
mentioned may be trademarks of their respective owners. No warranty as to accuracy
or completeness is expressed or implied. MSI reserves the right to make changes to
this document without prior notice.
Technical Support
If a problem arises with your product and no solution can be obtained from the user’s
manual, please contact your place of purchase or local distributor. Alternatively,
please visit https://eps.msi.com/support for further guidance.

6Safety Information
Safety Information
∙Always read the safety instructions carefully.
∙Keep this User’s Manual for future reference.
∙Keep this equipment away from humidity.
∙Lay this equipment on a reliable flat surface before setting it up.
∙The openings on the enclosure are for air convection hence protects the equipment
from overheating. Do not cover the openings.
∙Make sure the voltage of the power source and adjust properly before connecting
the equipment to the power inlet.
∙Place the power cord such a way that people can not step on it. Do not place
anything over the power cord.
∙Always unplug the power cord before inserting any add-on card or module.
∙All cautions and warnings on the equipment should be noted.
∙Never pour any liquid into the opening that could damage or cause electrical shock.
∙If any of the following situations arises, get the equipment checked by service
personnel:
∙The power cord or plug is damaged.
∙Liquid has penetrated into the equipment.
∙The equipment has been exposed to moisture.
∙The equipment does not work well or you can not get it work according to User’s
Manual.
∙The equipment has dropped and damaged.
∙The equipment has obvious sign of breakage.
∙Do not leave this equipment in an environment unconditioned, storage
temperature above 60°C (140°F), it may damage the equipment.

7
System Specifications
System Specifications
Model S2205-04
Form Factor 2U
Dimensions 17.2”W (438mm) x 3.4”H (87mm) x 30.3”D (770mm)
Processor ∙2 x Intel® Xeon® Processor Scalable Family (Socket-E)
-Sapphire Rapids (SPR)/ Emerald Rapids (EMR)
Chipset Intel® C741
Memory ∙32 x DDR5 RDIMM/ RDIMM-3DS, w/ ECC
-SPR: 4800MTs (1DPC)/ 4400MTs (2DPC)
-EMR: 5600MTs (1DPC)/ 4800MTs (2DPC)
-8 x Channels DDR5 per CPU/ 2DPC 16 DIMMs per socket
Internal
Storage
∙2 x M.2 M-key (22110/ 2280)
∙1 x MicroSD (internal)
Drive Bays ∙24 x 2.5” Hybrid hot-swap drive bay
-24x NVMe or 16x NVMe + 8x SATA
∙4 x 2.5” SATA Hot-swap drive bays (external rear)
Expansion
Slots
∙4 x PCIe slots
-Riser1: 1 x FH Gen 4 (x16/0/0)
-Riser2: 3 x FH Gen 4 (x8/x16/x8)
∙1 x OCP 3.0 Mezzanine card slot
Security ∙TPM 2.0
∙Case intrusion switch
Server
Management
∙Aspeed AST2600 IPMI 2.0 with iKVM support
∙1 x GbE RJ45 (1x Mgmt.)
Cooling ∙2 x CPU EVAC with air duct @350W
∙2 x Passive CPU heatsink with air duct @250W (Optional)
Environmental ∙System Operating Temperature: 0°C ~ 35°C
∙Non-operating Temperature: -20°C ~ 70°C
∙Non-operating Relative Humidity: 5% ~ 85% (non-condensing)
Certications CE, FCC (Class A)

8System Overview
System Overview
22
33
44
16 x 2.5” NVMe
Hot-Swap Drive Bays 8 x 2.5” NVMe/ SATA Hybrid Hot-Swap Drive Bays 66
55
11
4 x 2.5” SATA
Hot-Swap Drive Bays
(Optional)
771188991010 221111
Riser #1Riser #1 Riser #2Riser #2
1212

9
System Overview
11USB 2.0 Port
This connector is provided for USB peripheral devices. (Speed up to 480 Mbps)
22VGA Port
33System Power Button/ LED
44UID Button/ LED
55System Reset Button
66
!
System Status LED
1
NIC Link LEDs
M.2 Activity LED
77UID LED Button (or BMC Reset Button, via jumper: J1_1)
88RJ45 Serial Console Port
99
GbE RJ45 Port (Optional)
The standard RJ45 LAN jack is provided for connection to the Local Area
Network (LAN). You can connect a network cable to it.
SPEED
LED
LINK/ACT
LED
LED Status Description
Link/ Activity
LED
Off No link
Green Linked
Blinking Data activity
Speed LED
Off 10 Mbps/
No LAN linked
Orange 100 Mbps
Green 1 Gbps

10 System Overview
1010
GbE RJ45 Port (for Mgmt.)
The standard RJ45 LAN jack is provided for connection to the Local Area
Network (LAN). You can connect a network cable to it.
LINK/ACT
LED
SPEED
LED
LED Status Description
Link/ Activity
LED
Off No link
Green Linked
Blinking Data activity
Speed LED
Off 10 Mbps
Orange 100 Mbps
Green 1 Gbps
1111 Power Supply Unit
1212 PCIe Add-in Card Area

11
System LED Indicators
System LED Indicators
System Power Button/ LED
System Reset Button
UID Button/ LED
!
System Status LED M.2 Activity LED
1
NIC Link LED
LED LED State Description
Power LED Blue System power is on
System power is on ACPI S0 state
Blinking System is sleeping
Off System power is off
System power is on ACPI S4, S5 state
UID LED Blue Identify active via command or button
Off No identification
!
System Status LED Red System has failed
Off System power is not present
1
NIC Link LED Green NIC link is established
Blinking NIC activity is occurring
Off NIC link is not established
M.2 Activity LED Green M.2 present, no activity
Blinking M.2 accessing
Off No M.2 activity

12 Motherboard Overview
Motherboard Overview
JVROC1
CPU0_DIMM_D1 CPU0_DIMM_D2 CPU0_DIMM_C1 CPU0_DIMM_C2 CPU0_DIMM_B1 CPU0_DIMM_B2 CPU0_DIMM_A1 CPU0_DIMM_A2
CPU0_DIMM_E2
CPU0_DIMM_E1
CPU0_DIMM_F2 CPU0_DIMM_F1
CPU0_DIMM_G2
CPU0_DIMM_G1
CPU0_DIMM_H2 CPU0_DIMM_H1
CPU1_DIMM_D1
CPU1_DIMM_D2 CPU1_DIMM_C1 CPU1_DIMM_C2 CPU1_DIMM_B1 CPU1_DIMM_B2
CPU1_DIMM_A1
CPU1_DIMM_A2
CPU1_DIMM_E2
CPU1_DIMM_E1 CPU1_DIMM_F2 CPU1_DIMM_F1 CPU1_DIMM_G2
CPU1_DIMM_G1
CPU1_DIMM_H2 CPU1_DIMM_H1
CPU1 CPU0
F1U-8
F1U-7
F1U-6
JPWR1 JPWR2
OCP1
JPWR3
JPWR4
JPWR5
JPWR11
JPWR6
JPWR10
JBMC_USB1
JRPWR1
JSATA1
JSATA2
JTPM1
JSATA3
JSPI1
JVNN_PCH1
BAT1
SSATA1
SSATA2
JPWR7
JUSB2
JUSB1
JFAN1
JFAN2
JPWR9
JMCIOP0_1
JMCIOP0_2
JMCIOP0_3
JMCIOP0_4
JMCIOP1_1
JMCIOP1_2
JMCIOP1_3
JMCIOP1_4
JPWR8
F1U-5
F1U-4
F1U-3
F1U-2
F1U-1
F2U-6
F2U-5
BMC_F1
FP_I2C_1
BP_I2C_1
JSGPIO_PCH1
BP_I2C_2
BIOS2 BIOS1
JIPMB1
JFP_VGA1
JFP1
BMC_F2
M2_1
M2_2
MSD1
VGA1
MLAN1
COM1
USB2
USB1
JUID
RISER1
RISER2
RISER4
RISER3
F2U-4
F2U-2
F2U-3
F2U-1
J1_1
JBAT1
JCHASSIS1
JSEL_BMC1
JSEL_BIOS1
LED_L1
LED_H1
LED1

13
Motherboard Connectors
Motherboard Connectors
Power Connectors
JPWR1~2: CRPS Power Connectors
These CRPS (Common Redundant Power Supplies) connectors allow you to connect
a power supply. To connect the power supply, ensure that the plug is inserted in the
proper orientation and that the pins are aligned. Then firmly push down the power
supply into the connector.
JPWR3~6, JPWR10~11: GPU Power Connectors
These connectors provide power output to GPUs.
JPWR8~9: HDD BP Power Connectors
These connectors provide power output to HDDs.
1
4
85
JPWR3
JPWR4
JPWR5
JPWR8
JPWR6
JPWR9
JPWR10
JPWR11
1 GND 2 GND
3 GND 4 GND
5 +12V 6 +12V
7 +12V 8 +12V
JPWR9 JPWR8
JPWR11
JPWR6
JPWR10
JPWR5
JPWR3
JPWR1 JPWR2
JPWR4
JPWR7

14 Motherboard Connectors
JPWR7: Rear Side BP Power Connector
This connector provides power output to HDDs on rear side.
JPWR7
21
3 4
1 GND 2 GND
3P12V 4P5V
⚠
Important
Make sure that all power connectors are securely connected to the power supply to
ensure stable operation of the motherboard.

15
Motherboard Connectors
Storage Connectors
Slot Speed
SSATA1, SSATA2 SATA 6Gb/s
JSATA1~3 SATA 6Gb/s
M2_1, M2_2 PCIe3.0 x2 8GT/s
JMCIOP0_1~4
JMCIOP1_1~4 PCIe4.0 x8 16GT/s
SSATA1~2: SATA 3.0 DOM Ports (6Gb/s)
These connectors are SATA 6Gb/s interface ports. Each connector can connect to one
SATA device.
SSATA1~2
71
1 GND 5 TX_DN
2 RX_DP 6 TX_DP
3 RX_DN 7 GND
4 GND
⚠
Important
∙ Please do not fold the SATA cable at a 90-degree angle. Data loss may result during
transmission otherwise.
∙ SATA cables have identical plugs on either sides of the cable. However, it is
recommended that the flat connector be connected to the motherboard for space
saving purposes.
JMCIOP1_1 JMCIOP0_1
JMCIOP1_2 JMCIOP0_2
JMCIOP1_4 JMCIOP0_4
SSATA2
M2_1
MSD1
M2_2
SSATA1
JSATA3
JSATA2
JSATA1
JMCIOP1_3 JMCIOP0_3
1
1
11
4
4
44
3
3
33
2
2
22

16 Motherboard Connectors
JSATA1~3: Slimline SAS 4i Connectors (12 x SATA 3.0)
These connectors provide storage support for SATA devices.
JSATA1~3
B1 B19
A1 A19
A1 GND B1 GND
A2 JSATA_P0_RX+ B2 JSATA_P0_TX+
A3 JSATA_P0_RX- B3 JSATA_P0_TX-
A4 GND B4 GND
A5 JSATA_P1_RX+ B5 JSATA_P1_TX+
A6 JSATA_P1_RX- B6 JSATA_P1_TX-
A7 GND B7 GND
A8 BP TYPE B8 SGPIO_SATA_CLOCK_R
A9 SGPIO_SATA_DATAOUT_R B9 SGPIO_SATA_LOAD_R
A10 GND B10 GND
A11 NC B11 P3V3
A12 NC B12 NC
A13 GND B13 GND
A14 JSATA_P2_RX+ B14 JSATA_P2_TX+
A15 JSATA_P2_RX- B15 JSATA_P2_TX-
A16 GND B16 GND
A17 JSATA_P3_RX+ B17 JSATA_P3_TX+
A18 JSATA_P3_RX- B18 JSATA_P3_TX-
A19 GND B19 GND

17
Motherboard Connectors
JMCIOP0_1~4, JMCIOP1_1~4: MCIO 8i Connectors
These are vertical 74-pin Mini Cool Edge IO (MCIO) connectors, which support PCIe 4.0
x8 16GT/s interface.
JMCIOP0_1~4
JMCIOP1_1~4
B37
A37
B1
A1
A1 GND B1 GND
A2 SSD_RX+ B2 SSD_TX+
A3 SSD_RX- B3 SSD_TX-
A4 GND B4 GND
A5 SSD_RX+ B5 SSD_TX+
A6 SSD_RX- B6 SSD_TX-
A7 GND B7 GND
A8 NC B8 SMB_PEHPCPU_LV3_SCL
A9 FM_SMB_CPU_ALERT_N B9 SMB_PEHPCPU_LV3_SDA
A10 GND B10 GND
A11 CLK_100M_SSD_DP B11 RST_PCIE_CPU_PERST_N
A12 CLK_100M_SSD_DN B12 FM_PCIE_SSD_PRSNT_N
A13 GND B13 GND
A14 SSD_RX+ B14 SSD_TX+
A15 SSD_RX- B15 SSD_TX-
A16 GND B16 GND
A17 SSD_RX+ B17 SSD_TX+
A18 SSD_RX- B18 SSD_TX-
A19 GND B19 GND
A20 SSD_RX+ B20 SSD_TX+
A21 SSD_RX- B21 SSD_TX-
A22 GND B22 GND
A23 SSD_RX+ B23 SSD_TX+
A24 SSD_RX- B24 SSD_TX-
A25 GND B25 GND
A26 NC B26 SMB_PEHPCPU_LV3_SCL
A27 FM_SMB_CPU_ALERT_N B27 SMB_PEHPCPU_LV3_SDA
A28 GND B28 GND
A29 CLK_100M_SSD_DP B29 RST_PCIE_CPU_PESET_N
A30 CLK_100M_SSD_DN B30 FM_PCIE_SSD_PRSNT_N
A31 GND B31 GND
A32 SSD_RX+ B32 SSD_TX+
A33 SSD_RX- B33 SSD_TX-
A34 GND B34 GND
A35 SSD_RX+ B35 SSD_TX+
A36 SSD_RX- B36 SSD_TX-
A37 GND B37 GND

18 Motherboard Connectors
M2_1, M2_2: M.2 Slot (M Key, PCIe 3.0 x2, 22110/ 2280)
The M.2 slot supports solid-state drive (SSD). For Installation procedure, please refer
to “System Setup > M.2 M Key".
MSD1: Micro SD Card Slot
This slot is for inserting the micro SD card.

19
Motherboard Connectors
FPC Connectors
A Flexible Printed Circuit (FPC) connector connects a flexible printed circuit or flat
ribbon cable to a PCB. FPC connectors are also referred to as flat flexible cable (FFC)
connectors or ribbon connectors. Their slim and lightweight design makes them ideal
for electronic devices and equipment that require space-saving solutions.
JFP1
JUSB2
JFP1: Front Panel FPC Connector
The front panel connector is provided for electrical connection to the front panel
switches and LEDs.
JFP1
1 26
1P3V3_AUX 2P3V3_AUX
3N/A 4FP ID LED+
5PWR_LED- 6FP ID LED-
7P3V3 8SYS_FLT_LED-
9SYS_ERR_LED- 10 M.2 SSD_ACT_LED-
11 PWR_ON_BTN- 12 NIC1_LED+
13 GND 14 NIC1_LED-
15 SYS_RST_BTN- 16 SMB_DAT
17 SMB_CLK 18 GND
19 FP_ID_BTN- 20 N/A
21 N/A 22 N/A
23 NIC2_LED+ 24 NIC2_LED-
25 GND 26 GND

20 Motherboard Connectors
JUSB2: USB FPC Connector
This port is backward-compatible with USB 2.0 devices and supports data transfer
rate up to 480 Mbit/s (Hi-Speed).
JUSB2
1 26
1USB_VCC1 2USB_VCC1
3USB_VCC1 4USB_VCC1
5USB_VCC1 6USB_VCC1
7GND 8GND
9GND 10 GND
11 GND 12 GND
13 GND 14 GND
15 USB3_PO4_ESD_RXN 16 USB3_P04_ESD_RXP
17 GND 18 USB3_P04_ESD_TXN
19 USB3_P04_ESD_TXP 20 GND
21 PCH_USB2_P02_ESD_DN 22 PCH_USB2_PO2_ESD_DP
23 GND 24 PCH_USB2_PO3_ESD_DN
25 PCH_USB2_PO3_ESD_DP 26 GND