RR Mechatronics STARRSED RS User manual

USER MANUAL
STARRSED RS
Version 6.70 MRN-071_1-EN
Master Registration Number: MRN-071_1-EN

Manufacturer: RR Mechatronics Manufacturing B.V.
Phone: [phone]
Fax: [phone]
E-mail: [e-mail]
Internet: http://www.rrmechatronics.com
Postal address:
P.O. Box 225
1620 AE Hoorn
The Netherlands
Office address:
De Corantijn 13
1689 AN Zwaag
The Netherlands
© Copyright R&R Mechatronics Manufacturing B.V.
All rights reserved.
Subject to changes without prior notice.
Issued by the Support Department of RR Mechatronics

Document history overview
Starrsed RS User Manual Page 3
Version 6.70 MRN-071 (A)-EN
Document history overview
MRN--071_1-EN
Published date Wednesday, 12 July 2017
Issue No Date Revised Section(s) Changes Authorised
6.70 July 2017 Introduction
Safety
Maintenance
• Additions to introduction chapter
• Explanation of symbols
• Updated maintenance
instructions and maintenance
information
H.
Schavemaker
6.69 December
2015
Maintenance
Appendix
• Addition of technical
specifications
• Instrument naming
• WI-194/198 modified
• R-3500 EPU Protocol changed
H.
Schavemaker
6.68 October 2014 Introduction
Safety
Technical
specifications
History screen
Service screen
Data management
Appendix
• General safety instructions
• Explanation of documentation
• Fill and clean instructions
modified
• Result path
• TCP/IP
• Protocol R-3500 EPU added
• Error list revised and E21, E29,
E32 added
H.
Schavemaker
6.67 August 2014 Service Screen
• Temporary release H.
Schavemaker
6.66 November
2013
History Screen
Settings Screen
Quality Control
Trouble shooting
• Introduction of chapter Quality
Control
• Barcode reader/tube detection
rewritten
H.
Schavemaker

Document history overview
Page 4 Starrsed RS User Manual
Version 6.70 MRN-071 (A)-EN
6.65 February
2013
History screen
Maintenance
screen
Maintenance
Error list
• Addition print result header
• Hazy aspect not suppressed in
case of limit error
• Prime/Clean text
• Maintenance items up to level 4
included
• Reagent installation
• Error 19 added
H.
Schavemaker
6.64 July 2012 Reagents screen
Limit error settings
screen
Reporting
Operation
Trouble shooting
• Reagent barcode reader
• Limit error settings
• Air bubble trouble shooting
• Changed the value for Abs from
340 to 300
H.E. van Dijk
6.63 January 2012 annual update H.E. van Dijk
6.62 June 2011 Turn off
Getting started
• It is not a problem if the Starrsed
Auto-Compact is on all the time.
However,....>
• Check limit settings
• Update screen pictures
H.E. van Dijk
6.61 February
2011
Main screen
History screen
Explain Rack pictogram H.E. van Dijk
6.60 July 2010 Appendix
Settings
• Add new the new
MECHATRONICS 01 and 02
string
• Language selection
• Make a new Settings screen for
limit error
• Replaced History and
Amendment record for Document
history
H.E. van Dijk
6.50 July 2009 Reporting section Add new analyzer error number to
the list. 7 is limit error.
H.E. van Dijk
6.40 June 2009 Update screens to
apply for the
software update
version 2.22
• Update screens to apply for this
software update in Auto Compact
Program
H.E. van Dijk
6.30 September
2008
Removed
installation section
from manual
• Removed the installation section
from the manual and insert this in
Installation manual.
H.E. van Dijk

Document history overview
Starrsed RS User Manual Page 5
Version 6.70 MRN-071 (A)-EN
6.20 February
2008
Combine Auto
Compact and
InteRRliner V8
manual
• Combine Auto Compact manual
and InteRRliner V8 manual into
one manual.
• Changes are made on code
levels.
H.E. van Dijk
6.10 July 2007
• Re install missing link Appendix
Error list Auto Compact
• In Self close script set timer
longer
H.E. van Dijk
6.00 March 2007 Section 5 & 3
• All screen shoots are updated for
software version 2.13 and higher.
• Add self closing up-pops screens.
• Installation section 3 and text
how to connect the PC to the
Auto Compact and host
• Section 5 all kind of changes.Add
appendix PC connections.
• Some spell corrections in the
manual.
H.E. van Dijk
5.00 April 2006 Work instructions
• Review all the Work instructions
and add the latest information to
the instructions.
• Review the Maintenance
schedule
Add missing maintenance item to
section 11
• Add instructions to the
Maintenance schedule
• Add new work instructions WI
204 and WI 205
H.E. van Dijk
4.00 December
2005
Renumber the
section 5.6.1.2 to 3
Renumber section
5.6.1.3 to 4
Insert section
5.6.1.2 Conveyer
motor test
Insert in the 5.4 the
fill and clean
procedure
• All the screen shots are updated
Add new work instructions 202
and 203
• Correction made in WI 191, 192,
193, 194
• Add in settings-carrousel the
pipette flow diagram pop-up
screens
H.E. van Dijk

Document history overview
Page 6 Starrsed RS User Manual
Version 6.70 MRN-071 (A)-EN
3.00 September
2005
All sensor values
are the same in the
following sections;
Appendix
Maintenance
Section Check
sensor
Work instruction
186
• Sensor information in all sections
the same. Add link Weekly WI
191 in Work instruction contents
H.E. van Dijk
2.00 July 2005
• Rewrite the installation section. H.E. van Dijk
1.00 December
2004
• Make corrections and add the
latest pictures
• Update the sections according
the latest version of the Graphic
User Interface
H.E. van Dijk
Preliminary November
2003
• Start of he manual H.E. van Dijk

Contents
Starrsed RS User Manual Page 7
Version 6.70 MRN-071 (A)-EN
CONTENTS
1. INTRODUCTION ........................................................................................................ 14
1.1. Intended use of device........................................................................................... 14
1.2. Indication for use of device .................................................................................... 14
1.3. Instrument overview............................................................................................... 15
1.4. Explanation of symbols .......................................................................................... 16
1.5. EQAS .................................................................................................................... 17
1.6. Explanation of available documentation................................................................. 17
1.7. Dilution principle .................................................................................................... 17
1.8. Sedimentation measurement principle ................................................................... 18
2. INSTRUMENT DESCRIPTION ................................................................................... 19
2.1. Technical specifications ......................................................................................... 21
2.2. Technical specifications contd. .............................................................................. 23
2.3. Used reagents ....................................................................................................... 24
2.3.1. Starrsed Rinse solution ............................................................................... 24
2.3.2. Starrsed Saline............................................................................................ 24
2.3.3. Starrsed Diluent .......................................................................................... 24
2.3.4. Deionized water .......................................................................................... 24
2.3.5. Starrsed Disinfectant................................................................................... 24
2.3.6. Starrsed Cleaning Agent ............................................................................. 25
2.4. Accessory kit ......................................................................................................... 25
2.5. Starrsed line of ESR instruments ........................................................................... 25
3. GENERAL SAFETY INSTRUCTIONS........................................................................ 26
3.1. Safety warning....................................................................................................... 26
3.2. StaRRsed Incident Report ..................................................................................... 27
4. INSTALLATION ......................................................................................................... 28
5. STANDARD OPERATING PROCEDURES (S.O.P.) .................................................. 29
5.1. Basics of Bio safety ............................................................................................... 29
5.2. S.O.P. for working with bio hazardous materials .................................................... 30
5.2.1. Facts and definitions: .................................................................................. 30
5.2.2. Medical requirements:................................................................................. 30
5.2.3. General laboratory practices: ...................................................................... 30
5.2.4. Specific laboratory practices and requirements: .......................................... 31
5.3. E.C. Declaration Starrsed RS ................................................................................ 32
5.4. Labels and stickers on containers.......................................................................... 33
5.4.1. Stickers for the onboard reagents bottles .................................................... 33
5.4.2. Stickers of the reagents containers ............................................................. 34
6. STARRSED RS PROGRAM....................................................................................... 35
6.1. Software version .................................................................................................... 36

Contents
Page 8 Starrsed RS User Manual
Version 6.70 MRN-071 (A)-EN
6.2. Sample screen....................................................................................................... 36
6.2.1. Sample screen sections explanation ........................................................... 38
6.2.2. Sample screen with keyboard ..................................................................... 40
6.2.3. Pipette information ...................................................................................... 41
6.3. History screen........................................................................................................ 42
6.3.1. Display pipette data..................................................................................... 43
6.3.2. Display Sample history................................................................................ 44
6.3.2.1. Display patient results............................................................................. 45
6.3.3. Display rack history ..................................................................................... 47
6.3.3.1. Display rack status.................................................................................. 48
6.3.4. ESR Statistics screens ................................................................................ 49
6.3.5. QC Results screens .................................................................................... 50
6.3.5.1. QC Normal results (table) ....................................................................... 50
6.3.5.2. QC normal results screen extended ........................................................ 52
6.3.5.3. QC normal results (graph)....................................................................... 52
6.3.5.4. QC abnormal results (table) .................................................................... 53
6.3.5.5. QC abnormal results screen extended .................................................... 55
6.3.5.6. QC abnormal results (graph)................................................................... 56
6.3.5.7. Display sample history (QC).................................................................... 57
6.3.5.8. Linked QC ID's........................................................................................ 58
6.3.5.9. QC Result analysis ................................................................................. 59
6.3.6. History analyse............................................................................................ 59
6.3.7. History analyse results high dilution ............................................................ 60
6.3.8. History aspect ............................................................................................. 60
6.3.9. History analyse error ................................................................................... 61
6.3.10. History analyse warning .............................................................................. 61
6.3.11. History sample analyse option..................................................................... 62
6.3.12. History sample analyse option day.............................................................. 62
6.3.13. Set start date............................................................................................... 63
6.3.14. Set end date................................................................................................ 63
6.4. Reagents screen.................................................................................................... 64
6.4.1. Display reagent history................................................................................ 65
6.4.2. New reagent input ....................................................................................... 65
6.4.2.1. New reagent input (cont)......................................................................... 66
6.5. Maintenance screen .............................................................................................. 67
6.5.1. Prime / Clean .............................................................................................. 68
6.5.1.1. Fill and clean screen ............................................................................... 70
6.5.1.2. End-of-day-wash procedure.................................................................... 70
6.5.2. Check sensors ............................................................................................ 71
6.5.2.1. Check sensors in service mode .............................................................. 73
6.5.2.2. Fill stop sensor........................................................................................ 74
6.5.2.3. Temperature sensor................................................................................ 74
6.5.2.4. Diluter start ............................................................................................. 74
6.5.2.5. Diluent flow sensor.................................................................................. 74
6.5.2.6. Separator sensor .................................................................................... 74
6.5.2.7. Flow sensor ............................................................................................ 74
6.5.2.8. Measure sensor ...................................................................................... 75
6.5.3. Display error history .................................................................................... 76
6.5.4. Display maintenance history........................................................................ 76
6.5.5. Maintenance info......................................................................................... 77

Contents
Starrsed RS User Manual Page 9
Version 6.70 MRN-071 (A)-EN
6.5.6. Close........................................................................................................... 78
6.5.7. End-of-day-wash schedule settings............................................................. 78
6.5.8. End-of-day-wash options............................................................................. 79
6.6. General settings..................................................................................................... 80
6.6.1. Carousel control .......................................................................................... 83
6.6.1.1. Flow test potentiometer mean ................................................................. 85
6.6.1.2. Flow test flow .......................................................................................... 85
6.6.1.3. Flow test absolute ................................................................................... 86
6.6.1.4. Flow test leakage .................................................................................... 86
6.6.1.5. Flow test Fill sensor air ........................................................................... 87
6.6.1.6. Flow test Fill sensor glass ....................................................................... 87
6.6.1.7. Flow test start ......................................................................................... 88
6.6.1.8. Set new rinse position............................................................................. 88
6.6.2. Diluter settings ............................................................................................ 89
6.6.2.1. Dilution adjustment 60 till 140% .............................................................. 89
6.6.2.2. Dilution error detection 0 till 25%............................................................. 89
6.6.2.3. Auto dilution adjust.................................................................................. 90
6.6.2.4. Diluent flow check ................................................................................... 90
6.6.3. Limit error settings....................................................................................... 91
6.6.4. QC Settings................................................................................................. 92
6.7. Service screen....................................................................................................... 94
6.7.1. Rack unit setting.......................................................................................... 95
6.7.1.1. Mixer motor............................................................................................. 96
6.7.1.2. Conveyer motor ...................................................................................... 97
6.7.1.3. Position motor......................................................................................... 97
6.7.1.4. Timing settings...................................................................................... 100
6.7.2. LIMS settings ............................................................................................ 101
6.7.2.1. Set LIMS communication settings ......................................................... 101
6.7.2.2. Set protocol settings ............................................................................. 102
6.7.3. Compact settings ...................................................................................... 103
6.7.3.1. Printer port ............................................................................................ 104
6.7.3.2. Compact connected to .......................................................................... 104
6.7.3.3. Select barcode reader........................................................................... 104
6.7.3.4. Result path............................................................................................ 104
6.7.3.5. USB IO Device...................................................................................... 104
6.7.3.6. Search in example history..................................................................... 104
6.7.3.7. Outer needle depth ............................................................................... 104
6.7.4. Manual control........................................................................................... 105
6.7.4.1. Needle Control...................................................................................... 106
6.7.4.2. Valve control ......................................................................................... 107
6.7.4.3. Valves and Actuators ............................................................................ 107
6.7.5. Display maintenance history (Service) ...................................................... 108
6.7.6. Display error history (Service) ................................................................... 109
6.7.7. Advanced .................................................................................................. 110
7. GETTING STARTED ................................................................................................ 111
7.1. Liquid levels......................................................................................................... 111
7.2. Limit filter settings ................................................................................................ 111
7.3. Reagents preparation .......................................................................................... 111
7.3.1. Starrsed Rinse solution QRR 010934........................................................ 113

Contents
Page 10 Starrsed RS User Manual
Version 6.70 MRN-071 (A)-EN
7.3.2. Starrsed Saline QRR 010933.................................................................... 113
7.3.3. Starrsed Diluent QRR 010931................................................................... 113
7.3.4. De-ionised water ....................................................................................... 113
7.3.5. Starrsed Disinfectant QRR 010947 ........................................................... 114
7.3.6. Starrsed Cleaning Agent ........................................................................... 114
7.3.7. Waste disposal.......................................................................................... 114
8. REPORTING ............................................................................................................ 115
8.1. Protocols.............................................................................................................. 115
8.1.1. General Error codes in protocols............................................................... 116
8.1.2. String format for StaRRsed ....................................................................... 117
8.1.3. String format for StaRRsed (V14).............................................................. 119
8.1.4. Sedimatic 100 serial output ....................................................................... 121
8.1.5. Sedimatic 15 serial output ......................................................................... 123
8.1.6. Vesmatic serial output............................................................................... 124
8.1.7. Compact bi-directional protocol ................................................................. 132
8.1.8. Protocol Opus bidirectional........................................................................ 134
8.1.9. Protocol Sysmex R-3500........................................................................... 140
8.1.10. Protocol Sysmex R-3500 unidirectional..................................................... 143
8.1.11. Protocol Sysmex R-3500 EPU .................................................................. 145
8.1.12. Protocol Sysmex SE-9000......................................................................... 147
8.1.13. Protocol Sysmex SE-9000 unidirectional................................................... 150
8.1.14. Protocol TDLIMS....................................................................................... 152
8.2. Result Printout ..................................................................................................... 154
8.2.1. Report 60-Minute mode............................................................................. 154
8.2.2. Report 30 Minute mode............................................................................. 155
8.2.3. ESR Error.................................................................................................. 156
8.2.3.1. ESR Error and Warning code messages............................................... 156
8.2.4. Limit error settings..................................................................................... 158
8.2.5. Reporting range ........................................................................................ 158
8.2.6. Aspect Hazy.............................................................................................. 159
8.2.6.1. Analyser "HAZY" code messages ......................................................... 160
9. OPERATION ............................................................................................................ 161
9.1. Quick start-up ...................................................................................................... 161
9.1.1. Check list .................................................................................................. 161
9.1.2. Power up sequence................................................................................... 162
9.1.3. Fill procedure ............................................................................................ 162
9.1.3.1. Liquid levels .......................................................................................... 162
9.2. Checks during operation ...................................................................................... 163
9.3. Priming the fluid system....................................................................................... 163
9.4. Turn off ................................................................................................................ 164
9.4.1. End-of-day-wash procedure ...................................................................... 164
9.4.2. Turn off sequence ..................................................................................... 164
10. QUALITY CONTROL ............................................................................................... 165
10.1. Control pipettes ................................................................................................ 165
10.2. Monitoring measurement quality with Starrsed Control..................................... 165
10.2.1. Limitations................................................................................................. 165
10.2.2. Expected value range................................................................................ 166

Contents
Starrsed RS User Manual Page 11
Version 6.70 MRN-071 (A)-EN
10.2.3. Temperature correction ............................................................................. 166
10.2.4. Usage options ........................................................................................... 166
10.2.5. Quality control procedure .......................................................................... 167
10.2.6. QC Results................................................................................................ 168
10.2.6.1. QC Error messages ............................................................................ 168
10.2.6.2. QC Result analysis.............................................................................. 169
11. WASTE DISPOSAL.................................................................................................. 170
11.1. Replacing the waste container.......................................................................... 170
12. COMPACT SYSTEM MESSAGES ........................................................................... 171
12.1. System messages............................................................................................ 171
12.2. Test messages................................................................................................. 172
12.3. System time-out <xxxx> ................................................................................... 172
12.4. Error Messages................................................................................................ 172
13. MAINTENANCE ....................................................................................................... 173
13.1. Maintenance Schedule example....................................................................... 173
13.2. Daily................................................................................................................. 173
13.2.1. Check or replace sample probe or outer needle........................................ 174
13.3. Weekly ............................................................................................................. 175
13.3.1. Check the sensors in service mode........................................................... 176
13.3.2. Cleaning liquid separator........................................................................... 176
13.4. Level 4 maintenance ........................................................................................ 177
13.4.1. Rinse-pump tube replacement .................................................................. 177
13.4.2. Saline-pump tube replacement.................................................................. 178
13.4.3. Replace bacterial filters ............................................................................. 178
13.4.4. Fill-nozzle O-ring replacement................................................................... 179
13.4.5. Fill and clean procedure ............................................................................ 179
13.5. Level 3 maintenance ........................................................................................ 181
13.6. Level 2 maintenance ........................................................................................ 181
13.7. Level 1 maintenance ........................................................................................ 181
13.8. Reagents replacement ..................................................................................... 182
14. DATA SAFETY MANAGEMENT .............................................................................. 184
14.1. Power failure .................................................................................................... 184
14.2. PC output ......................................................................................................... 184
14.3. Specifications for the RS232 port ..................................................................... 184
14.4. Folder Structure on PC..................................................................................... 184
15. TROUBLE SHOOTING ............................................................................................ 185
15.1. Peristaltic pumps.............................................................................................. 185
15.1.1. Rinse solution not primed through the system........................................... 185
15.1.2. Rinse solution spilling over the instrument................................................. 186
15.1.3. Rinse pump failure .................................................................................... 186
15.1.4. Sample probe is not washed after aspiration............................................. 186
15.1.5. Saline dripping in the sample tube adapter................................................ 187

Contents
Page 12 Starrsed RS User Manual
Version 6.70 MRN-071 (A)-EN
15.1.6. Saline pump failure ................................................................................... 187
15.1.7. Pipettes not dry after washing and drying.................................................. 187
15.2. Liquid level sensor not sensing......................................................................... 187
15.3. Compact stalls.................................................................................................. 188
15.4. Diluter............................................................................................................... 189
15.4.1. Diluter system not sufficiently primed ........................................................ 189
15.4.2. Diluter errors ............................................................................................. 190
15.4.3. Air bubbles entering the Diluent system .................................................... 190
15.5. Vacuum............................................................................................................ 192
15.5.1. Vacuum stabilisation problems.................................................................. 192
15.5.2. Vacuum error ............................................................................................ 193
15.6. Flushing liquids ................................................................................................ 194
15.6.1. De-ionized water ....................................................................................... 194
15.6.2. Disinfectant ............................................................................................... 194
15.7. Needle system ................................................................................................. 195
15.7.1. Needle not in top position.......................................................................... 195
15.7.2. Sample probe fails to go down .................................................................. 195
15.8. Air bubbles ....................................................................................................... 196
15.8.1. Foam in column......................................................................................... 196
15.8.2. Pipette looks like zebra crossing ............................................................... 197
15.8.3. One air bubble about 5 mm under meniscus ............................................. 197
15.8.4. One air bubble rising in pipette.................................................................. 198
15.8.5. Small air bubbles rising in pipette.............................................................. 198
15.8.6. Random air bubbles in pipette................................................................... 199
15.9. Leaking pipettes ............................................................................................... 199
15.10. Rinse nozzle (wash station) alignment.......................................................... 200
15.11. Hazy reports ................................................................................................. 200
15.11.1. Hazy reports after cleaning.................................................................... 201
15.12. Contaminated instrument.............................................................................. 201
15.13. Fill time-out error........................................................................................... 201
15.14. Position error ................................................................................................ 202
15.15. Separator error ............................................................................................. 204
15.16. Reagents ...................................................................................................... 205
15.17. Reagents alarm ............................................................................................ 205
15.18. Fill nozzle...................................................................................................... 205
15.18.1. Fill nozzle does not engage with pipette ................................................ 205
15.18.2. Fill nozzle not at fill position ................................................................... 205
15.18.3. Fill nozzle not at home position.............................................................. 206
15.19. Piercing error ................................................................................................ 206
15.20. New rack adapter.......................................................................................... 207
15.21. Rack unit errors ............................................................................................ 207
15.21.1. Gripper module...................................................................................... 208
15.21.2. Mixer module ......................................................................................... 209
15.21.3. Check the mixer..................................................................................... 209
15.22. Communications........................................................................................... 210

Contents
Starrsed RS User Manual Page 13
Version 6.70 MRN-071 (A)-EN
15.23. Barcode reader test ...................................................................................... 210
15.24. Tube sensor detection test............................................................................ 210
15.25. Tube not in 1 position ................................................................................... 211
15.26. Temperature error......................................................................................... 211
15.27. Communication error (E2)............................................................................. 211
15.28. Quality control trouble shooting..................................................................... 213
16. APPENDIX FOR STARRSED AUTO-COMPACT .................................................... 216
17. WORK INSTRUCTION STARRSED AUTO-COMPACT........................................... 268
18. GLOSSARY OF TERMS .......................................................................................... 321
19. INDEX....................................................................................................................... 323

Introduction
Page 14 Starrsed RS User Manual
Version 6.70 MRN-071 (A)-EN
1. INTRODUCTION
1.1. Intended use of device
Automated analyser for in vitro determination of the Erythrocyte Sedimentation Rate (ESR) of
human blood samples in conformity with the Westergren standard. For professional use in medical
laboratories only. To be used for all patient populations, not restricted by age or any other
anatomical or physiological particulars.
1.2. Indication for use of device
For screening and follow-up of patients with (suspected) inflammatory conditions.

Introduction
Starrsed RS User Manual Page 15
Version 6.70 MRN-071 (A)-EN
1.3. Instrument overview
The Starrsed Blood Sedimentation Rate Instrument (hereafter called Starrsed Auto-Compact) is
an in vitro diagnostic medical device that automatically carries out the erythrocyte sedimentation
rate analysis according to the Westergren method, conforming to CLSI approved standard H02-
A5, using closed sample tubes filled with citrate or EDTA blood.
The Starrsed Auto-Compact is an advanced ESR system that offers many unique features and
benefits over the traditional ESR procedures. Automating this method has the following
advantages:
• The Westergren pipettes are always filled to the correct level.
• Using closed sample tubes reduces the possibility of contamination for the user and
environment.
• Standard glass Westergren pipettes are used, in which the measurement can be corrected to a
constant temperature (18 °C Celsius). Even small abnormalities can be detected over a longer
period of time, irrespective of where and when the blood sample was taken.
• Every sedimentation measurement is directly linked to an identified sample, so that a manual
work sheet is unnecessary. Patient ID errors are reduced to a minimum by using the bar-code
reader.
• In the EDTA mode, the accuracy of dilution of EDTA blood with citrate is considerably better
than manual dilution achieved either by "tipping off" or using evacuated blood collection tubes
pre-filled with citrate solution.
• The data can be send to your Lab Information System.
• The used sedimentation pipettes are automatically washed and dried.
• Minimum sample volume is 1.4 ml for the Starrsed Auto-Compact.
• The Starrsed Auto-Compact has fully automatic sample loading.
• The Rack system can work with a variety of hematology analyzer racks with most common
EDTA blood sample tubes.
The system uses rack adapters and is set up for a specific type of rack.
• Windows based System Software is running on an external computer.

Introduction
Page 16 Starrsed RS User Manual
Version 6.70 MRN-071 (A)-EN
1.4. Explanation of symbols
The following symbols can be used in this manual and for the instrument:
Warning sign to prevent personal injury due to biohazard.
Warning sign to prevent personal injury due to rotating parts.
Warning sign to prevent personal injury due to sharp objects.
Warning sign to prevent personal injury due to hot surfaces.
Warning sign to prevent personal injury due to electrical shocks.
General warning.
General note.
This symbol indicates a reference to this or other product
documentation

Introduction
Starrsed RS User Manual Page 17
Version 6.70 MRN-071 (A)-EN
1.5. EQAS
EQAS is RR Mechatronics' comprehensive tool to periodically assess the performance of the
Starrsed instrument at your lab. Through EQAS, the test results of the instrument, obtained with
Starrsed Control are objectively compared with a worldwide peer group using the same type of
instrument. Each customer can sign up for our portal, available through our website
http://www.rrmechatronics.com.
1.6. Explanation of available documentation
Manuals for the Starrsed Auto-Compact are available on three levels: for the operator, the
supervisor and the service engineer.
The following manuals are available:
1. Instructions for Use (IFU)
Intended for the operator: Contains instructions for normal operation, safety, preventive
maintenance and trouble shooting procedures to solve the most common problems. Available
in several languages.
2. User Manual (UM)
Intended for the lab supervisor. Contains information from the IFU and additional information
concerning settings, service, higher maintenance levels and trouble shooting procedures to
solve more complicated problems. Only available in English.
3. Service Manual (SM)
Intended for trained service engineers. Describes maintenance, servicing and repair of the
instrument in detail. Contains detailed descriptions of parts, assembly drawings, modifications,
extended trouble shooting, flow diagrams etc. Only available in English.
4. Installation Manual (IM)
Intended for trained service engineers. Contains instructions and procedures for installation
and start-up. Only available in English.
Manuals are available in PDF and HTML-format and can be downloaded from
http://www.rrmechatronics.com.
1.7. Dilution principle
The principle of adding Diluent to a flow of whole blood is unique. The Starrsed Auto-Compact has
the capability of monitoring the air displacement during the aspiration cycle. This is called on-line
dilution. The CPU receives data from the airflow sensor and calculates the syringe speed. Diluter
accuracy is ± 3%.
The citrate dilution (4:1) takes place to reduce the influence of HCt (Hematocrit) on the
sedimentation process. Dilution brings the Hct level from 0.45 (considered as a normal level) to
0.36. The ICSH (1993) recommended the use of EDTA samples with a Hct of 0.35 or less. Dilution
errors up to 25% results in a 5% variation in Hct of the prepared sample. This is within the natural
variation in Hct between individual humans and will not have significant influence on the accuracy
of the ESR measurement.

Introduction
Page 18 Starrsed RS User Manual
Version 6.70 MRN-071 (A)-EN
1.8. Sedimentation measurement principle
The automatic reading of the Westergren sedimentation pipettes is carried out by moving an
optical sensor along the pipettes. While the sensor is moving, a reading is made every 0.25 mm.
The sensor is reading the absorption of infrared light through the Westergren pipette filled with
blood. From these readings, values at a number of absorption levels are determined. All absorption
figures are relative to the darkest and lightest reading (darkest = 100 % and the lightest = 0 %
absorption respectively).
By definition the levels are:
87.5% Cells/ plasma separation
75.0% Hazy detection
50.0% Meniscus detection
Graphic showing typical absorption values of a sample