Thermo Scientific Microm HMS 740 User manual
Thermo Scientific Robot Stainer Microm HMS 740
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf / Germany
387801 - English
1
Thermo Scientific
Robot Stainer
Microm HMS 740
387801 Issue 10
INSTRUCTION MANUAL
Thermo Scientific Robot Stainer Microm HMS 740
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf / Germany
387801 - English
2
Thermo Scientific Robot Stainer Microm HMS 740
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf / Germany
387801 - English
3
CERTIFICATION
Thermo Fisher Scientific Microm International GmbH certifies that
this instrument has been tested and checked carefully. Its technical
data was verified before shipment to be in accordance with the
published specifications.
The instrument complies with applicable international safety
regulations.
WARRANTY
This Thermo Fisher Scienitific product is warranted against defects in
material and workmanship for a period of 1 year. Parts which prove
to be defective during the warranty period will be repaired or replaced
free of charge by the manufacturer. No other warranty is expressed
or implied. Unauthorized modification or repair by third party persons
will void the warranty.
The warranty will expire in case of improper or wrong use of the
instrument and in case the warning and precautionary messages are
not observed. Thermo Fisher Scienitific is not liable for any occurring
damage.
Errors and omissions excepted. Subject to amendment and
improvement without further notice.
This instruction manual will be supplied together with each
instrument. Further copies can be ordered at the nearest Thermo
Fisher Scienitific sales office by giving the serial number of the
instrument, the number of the instruction manual and the date of
issue.
This instruction manual is available in the following languages:
Cat. No.
German: 387800
English: 387801
French: 387802
Spanish: 387803
Italian: 387804
Thermo Scientific Robot Stainer Microm HMS 740
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf / Germany
387801 - English
4
Dear valued Customer,
Thank you for buying this Thermo Fisher Scientific instrument.
Before putting the instrument into operation, please read these operating
instructions carefully to familiarize you with its proper operation and
functions. To avoid risks for the operator and technical damage to the
instrument, it must only be used in accordance with its intended use (see
part 1-2).
Any other use of the instrument is considered improper! All warranties and
guarantees would then be null and void.
Only skilled or specially trained personnel must operate the slide stainer, i.e.
staining of histological and cytological specimens. The listed and marked
safety measures as well as the regulations and hygiene measures of your
respective lab must strictly be observed.
Serial No.: __________________
Please check the Serial No. on the type plate, which is placed on the rear
side of your instrument and enter this number here. This way, questions and
service can be handled faster.
Instruction Manual No. 387801
Issued on 12.08.2014
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf
Germany
Phone: +49.(0)6227.836-0
Fax: +49.(0)6227.836-111
Internet: www.thermoscientific.com
Thermo Scientific Robot Stainer Microm HMS 740
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf / Germany
387801 - English
5
Table of Contents
PART1 IMPORTANT INFORMATION
1-1 Warning signals and symbols
1-2 Intended use
1-3 Transportation lock
PART 2 INTRODUCTION
2-1 Description slide stainer Robot Stainer HMS 740
2-2 Accessories
2-2-1 Standard equipment
2-2-2 Additional accessories (optional)
2-2-3 Factory default settings
2-3 Technical data Robot Stainer HMS 740
PART 3 OPERATING INSTRUCTIONS
3-1 Setting up the slide stainer
3-2 Initial turn-on
3-2-1 Turning on and/or off the instrument
3-2-2 Log-in
3-3 Basic operational rules
3-3-1 Touch screen
3-3-2 Emergency shutdown
3-4 Creating and deleting a bath layout
3-4-1 Creating a bath layout
3-4-2 Deleting a bath layout
3-4-3 Time uncritical baths
3-4-4 Waste station
3-5 Creating, editing and deleting staining protocols
3-5-1 Creating staining protocols
3-5-2 Editing staining protocols
3-5-3 Deleting staining protocols
3-6 Starting staining protocols
3-7 Cancellation of staining protocol(s)
Thermo Scientific Robot Stainer Microm HMS 740
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf / Germany
387801 - English
6
3-8 Data security
3-8-1 Storing and loading protocols
3-8-2 Storing and loading bath layouts
3-9 Quality management and documentation
3-10 Settings
3-10-1 User settings
3-10-2 Install update
3-10-3 Service settings
PART 4 THEORY OF OPERATION OF THE ROBOT STAINER HMS 740
4-1 Structural design
4-2 Operating features
4-3 Function
PART 5 WORKING WITH THE ROBOT STAINER HMS 740
5-1 Preparations
5-2 Staining of specimens
5-3 How to avoid malfunctions
5-3-1 Possible sources of errors - cause and remedy
PART 6 MAINTENANCE AND CARE
6-1 Cleaning and care
6-2 Maintenance
6-3 Replacement work
6-3-1 Replacing the charcoal filter
PART 7 CONDITIONS FOR THE TRANSPORTATION OF THE INSTRUMENT
7-1 Taking back the instrument for repair or routine maintenance
7-2 Disposal of the instrument after final shutdown
Thermo Scientific Robot Stainer Microm HMS 740
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf / Germany
387801 - English
7
PART 1 IMPORTANT INFORMATION
1-1 WARNING SIGNALS AND SYMBOLS
The installation and routine use of the Robot Stainer HMS 740 is easy and safe if the instructions in this
manual are being observed.
Note:
Special instructions regarding operation of the instrument.
Caution:
Special precautionary measures to prevent damage to equipment. For a long lifetime of the
equipment, please observe these instructions carefully.
Danger:
Special warning messages to prevent harm to persons and/or serious damage to equipment. For
your own safety, please observe these instructions carefully.
Biohazard:
Warning of biological danger.
Radioactivity:
Warning of radioactive danger.
Hot surface:
Some surfaces of the instrument become hot during the intended use. They are marked with this
warning symbol. Touching these surfaces may cause burns.
Separate taking back of electrical and electronic instruments in the countries of the
European Union:
This is to be applied in the countries of the European Union and other European countries with a
separate collecting system within the waste management.
This product, being an electro and/or electronic instrument, must be treated separately within the
waste management process (WEEE).
Thermo Scientific Robot Stainer Microm HMS 740
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf / Germany
387801 - English
8
SAFETY PRECAUTIONS AND IMPORTANT INFORMATION
A T T E N T I O N !
The operator's safety is affected, when the instrument is not operated in accordance with this
instruction manual.
Please observe the following general precautions during operation of this instrument. Failure to
comply with these precautions violates safety standards and the intended use of the instrument.
Thermo Fisher Scientific is not liable for misuse of the instruments and failure to comply with basic
safety requirements.
INSTRUMENT GROUNDING
To avoid injury from electrical current, the instrument must be connected with the protective earth. The
instrument is equipped with a three wire ground plug. The power outlet must be connected to the protective
earth and must meet the International Electrotechnical Commission (IEC) regulations.
CAUTION: MAINS VOLTAGE
Never remove instrument covers during operation. Component replacements as well as adjustments must
only be made by trained service personnel. Only use original spare parts for replacement work. Unplug the
unit before removing or opening the covers.
DANGER IN EXPLOSIVE ENVIRONMENT
The instrument must not be operated in the presence of flammable gases. Moreover, the instrument must
not be exposed to conditions whereby dangerous gas concentrations can occur.
HAZARD OF RADIOACTIVE RADIATION
When working with radioactive specimens observe all applicable radiation safety procedures. When working
with radioactive contaminated material, appropriate safety and decontamination measures must be carried
out. According to the rules and regulations concerning the handling of radioactive contaminated material of
the respective laboratory, safety clothing (e.g. particle mask, gloves, protective shoe covers) must be worn.
Radioactive contaminated waste must be disposed of according to the respective regulations.
Thermo Scientific Robot Stainer Microm HMS 740
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf / Germany
387801 - English
9
HAZARD OF INFECTION
Specimens used during the intended operation of the instrument might potentially be infectious. For this
reason, it is recommended to observe the general laboratory regulations concerning protection against
danger of infection.
Information on decontamination media, their use, dilution and effective range of application can be read in
the Laboratory Biosafety Manual : 1984 of the World Health Organization.
When working with infectious specimens observe all applicable safety procedures. When working with
infectious material, appropriate safety and disinfection measures must be carried out. According to the rules
and regulations concerning the handling of infectious material of the respective laboratory, safety clothing
(e.g. particle mask, gloves, protective shoe covers) must be worn. Infectious waste must be disposed of
according to the respective regulations.
CAUTION! DANGER BY MOVING PARTS
Do not manipulate at the unit when the hood is open. To avoid danger, the moving speed is reduced.
CONSERVATION
According to environmental regulations, the occurring waste water should be drained into a discharge
channel with subsequent biological/chemical purification.
HAZARD OF MALFUNCTION
To avoid the hazard of malfunction of an instrument, it must only be operated in a controlled electromagnetic
environment. This means that transmitters such as mobile phones must not be operated in their close
vicinity.
Thermo Scientific Robot Stainer Microm HMS 740
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf / Germany
387801 - English
10
1-2 INTENDED USE
The Robot Stainer HMS 740 is a highly efficient
slide stainer. The Robot Stainer HM 420 must
solely by used for staining histological, cytological
and hematological stainings.
Only skilled or specially trained personnel must
carry out staining of histological, cytological and
hematological specimens with the Robot Stainer
HMS 740.
The listed and marked safety measures as well as
the regulations and hygiene measures of your
respective lab must strictly be observed.
Note:
This instruction manual is part of the
product.
Thermo Scientific Robot Stainer Microm HMS 740
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf / Germany
387801 - English
11
1-3 TRANSPORTATION LOCK
The Robot Stainer HMS 740 is equipped with
three transportation locks for the respective
moving axes (X, Y and Z axis).
Danger:
Before the initial turn-on of the
instrument, it is absolutely necessary
to remove the transportation locks!
(Please proceed as shown on the following page!)
Note:
The transportation locks must be kept
in a safe place to be able to install
them again in case of further
transportation.
Thermo Scientific Robot Stainer Microm HMS 740
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf / Germany
387801 - English
12
Transportsicherungen vor Inbetriebnahme entfernen!
Remove the transportation locks before the initial turn-on!
Enlever les verrouillages de transport avant la mise en service!
Retire los elementos de seguridad para transporte antes de su puesta en marcha!
1. X-Axis
2. Y-Axis
3. Z-Axis
Thermo Scientific Robot Stainer Microm HMS 740
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf / Germany
387801 - English
13
PART 2 INTRODUCTION
2-1 DESCRIPTION SLIDE STAINER ROBOT STAINER HMS 740
The Robot Stainer HMS 740 sets new standards in ergonomics, operation and comfort.
Different instrument versions:
HMS 740 standard instrument with 34 reagent stations, 4 rinsing stations, 3 exit and 1 entry station (cat.
no. 960300)
HMS 740 standard instrument with 32 reagent stations, 4 rinsing stations, 3 exit and 1 entry station and
2 DI stations (cat. no. 960310)
HMS 740 standard instrument with 32 reagent stations, 4 rinsing stations, 3 exit and 1 entry station and
2 heated reagent stations (cat. no. 960320)
HMS 740 with 4 heating stations, 30 reagent stations, 4 rinsing stations, 3 exit and 1 entry station (cat.
no. 960330)
HMS 740 with 4 heating stations, 28 reagent stations, 4 rinsing stations, 3 exit and 1 entry station and
2 DI stations (cat. no. 960340)
HMS 740 with 4 heating station, 28 reagent stations, 4 rinsing stations, 3 exit and 1 entry station and
2 heated reagent stations (cat. no. 960350)
The self-containing metal housing and the swing-open acrylic glass cover allow and easy access to the bath
containers. The bath containers can be removed individually or in groups of four and filled as needed.
The loading station and the three exit stations are user-friendly integrated into one drawer. This way, slide
baskets can comfortably inserted and removed without having to open the instrument hood.
Each bath container has an individual cover which is automatically lifted and transferred during protocol
execution. Bath size for one slide basket with 30 slides, bath capacity: 480 ml.
The slide baskets are permanently moved in the reagent containers (1 – 28). The agitation speed can be
selected and turned off, when needed.
The robotic arm, which is controlled in an intelligent way in three axes (x/y/z), with silent moving mechanics
is only used for transferring the slide baskets and the covers. Simultaneous multiple protocol execution
(multitasking) is possible.
The Robot Stainer HMS 740 is equipped with a new, almost maintenance-free drip preventer, which reduces
the reagent carry-over considerably.
Easy programming of the instrument via the large touch screen.
Fast creation of bath layouts and staining protocols via logical menu-driven prompting in various languages.
Protocol execution with minimal key sequence via touch screen or touchpad keyboard with five quick start
buttons.
Thermo Scientific Robot Stainer Microm HMS 740
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf / Germany
387801 - English
14
Protocol process is shown graphically on the screen. Different protocols are shown in different colors.
Additional acoustic warning signals in case of malfunctions.
Several bath layouts and up to 50 protocols with up 100 protocol steps each can be stored.
Immersion time can individually be selected between 1 sec. up to 99 min. 59 sec. in steps of seconds.
Reagent vapors are carried off via downwards ventilation flow and are inactivated via an easily accessible
active charcoal filter.
The Robot Stainer HMS 740 has an integrated uninterruptable power supply assuring that the running
protocols are completed in case of an error.
Thermo Scientific Robot Stainer Microm HMS 740
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf / Germany
387801 - English
15
TOTAL OVERVIEW ROBOT STAINER HMS 740
Fig. 1
1 = Hood
2 = Touch screen
3 = Quick start buttons
4 = Bath containers
5 = Exit/entry drawer
6 = Transportation arm
1
2 3 4 5
6
Thermo Scientific Robot Stainer Microm HMS 740
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf / Germany
387801 - English
16
2-2 ACCESSORIES
2-2-1 STANDARD EQUIPMENT
The slide stainer HMS 740 is supplied with the following standard equipment:
33 - 39 reagent containers (depending on the model)
43 covers
1 Gripping tool (for removing reagent containers in groups of four)
1 power cord 220 - 240 V/50 - 60 Hz
100 - 120 V/50 - 60 Hz
1 water filter
1 feed hose, 3 m (inner diameter 13 mm/thickness 3,5)
1 drain hose, 3 m (inner diameter 19 mm/thickness 4)
1 charcoal filter (already installed)
1 charcoal filter (reserve)
3 Allan keys, size 4, 5, 8
4 carrying handles
1 instruction manual
When ordering the version HMS 740 with DI water, the following accessories are also included in the
standard equipment:
1 feed hose for DI water
Note:
Please check all delivered parts with the delivery note and with your order. In case of a missing
part, please contact your local Thermo Scientific sales office immediately!
Thermo Scientific Robot Stainer Microm HMS 740
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf / Germany
387801 - English
17
2-2-2 ADDITIONAL ACCESSORIES (OPTIONAL)
Cat. No.
Reagent container 556240
Cover 425780
Charcoal filter 184000
Standard basket for CoverTech (30) 172550
Basket carrier for standard baskets 556200
Basket carrier for Sakura (tape coverslipper), (1x20) 556220
Basket carrier for Meisei/Medite (1x30) 556230
Basket carrier for Leica (1x30) 556210
Rack for four containers 425790
Thermo Scientific Robot Stainer Microm HMS 740
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf / Germany
387801 - English
18
2-2-3 FACTORY DEFAULT SETTINGS
Feature Setting
Standard passwords:
User (routine user) admin
Supervisor admin
Note:
When entering the passwords, please note the correct capital and/or small letters!
Thermo Scientific Robot Stainer Microm HMS 740
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf / Germany
387801 - English
19
2-3 TECHNICAL DATA ROBOT STAINER HMS 740
Slide capacity: ................................................................................... 1 x 30 slides
Bath capacity: .............................................................................................480 ml
Protocols: .............................................................50 protocols can be stored
Protocol steps: .......................................................... max. 100 steps per protocol
Immersion time: 1 sec. - 99 min. 59 sec. in steps of seconds
Transportation & storage conditions
Temperature range: ......................................................................... -20°C up to +50°C
Water pressure: ....................................................................between 2,5 and 4 bar
DI water pressure: ....................................................................between 0,2 and 4 bar
Operating conditions: ........................+5°C up to +35°C (at a max. rel. humidity of 60%)
......................................................... altitude up to 2000 m M.S.L.
..........................................................................for indoor use only
Power requirements:
............................................. 100 - 240 V 10 A +/-10% 50...60 Hz
Internal protection
Secondary circuits: .........................................1 x 27 VDC/T8AH, 2 x 48 VDC/T8.0AH
Primary circuits: ................................................................... Circuit breaker T10AH
Floor loading requirements:...................................................................................... 225 kg/m2
Pollution degree: ......................................................................................................2
Overvoltage category: ......................................................................................................II
Acoustic pressure: ............................................................................................47 dBA
Dimensions: .......................................... 1160 mm x 685 mm x 715 mm (w/h/d)
Weight: .............................................................................................160 kg
Thermo Scientific Robot Stainer Microm HMS 740
Microm International GmbH
part of Thermo Fisher Scientific
Otto-Hahn-Str. 1A
69190 Walldorf / Germany
387801 - English
20
1
2
3
4
PART 3 OPERATING INSTRUCTIONS
3-1 SETTING UP THE SLIDE STAINER
Unpacking the instrument:
Loosen and remove the tightening straps.
Remove the wooden top (fig. 2.1).
Lift the case over the instrument (fig. 2.2). The
instrument is placed on a pallet.
Remove accessories (carton inside the
instrument) as well as the packaging inserts (fig.
2.3).
Install the attached carrying handles to the
intended fastenings on the side (fig. 2.4).
Note:
To guarantee a safe transportation,
please fasten the four handles on the
instrument.
Carry the instrument to the site of installation
and place it on an even surface.
Danger:
Before the initial turn-on, first remove
the transportation locks. Then remove
the foamed cover.
Open the acrylic hood and remove the
transportation locks of all moving axes by means
of the attached tools.
After having removed the transportation lock:
Slightly press the Z module upwards.
Remove the small foamed part between Z and
CP module.
Carefully move the CP module upwards.
Remove the foamed cover.
In case of an uneven table surface, the
instrument feet can be adjusted in a way that a
horizontal alignment in X- and Y-direction is
guaranteed.
Note:
Carefully keep the shipping container
and the carrying handles for possible
return shipments.
Fig. 2
Table of contents
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