Asus D642MF User manual

Desktop PC
D642MF / D6421SFF
User Guide

2
Copyright © 2019 ASUSTeK Computer Inc. All Rights Reserved.
No part of this manual, including the products and software described in it, may be reproduced,
transmitted, transcribed, stored in a retrieval system, or translated into any language in any form or by any
means, except documentation kept by the purchaser for backup purposes, without the express written
permission of ASUSTeK Computer Inc. (“ASUS”).
Product warranty or service will not be extended if: (1) the product is repaired, modied or altered, unless
such repair, modication of alteration is authorized in writing by ASUS; or (2) the serial number of the
product is defaced or missing.
ASUS PROVIDES THIS MANUAL “AS IS” WITHOUT WARRANTY OF ANY KIND, EITHER EXPRESS
OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE IMPLIED WARRANTIES OR CONDITIONS OF
MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. IN NO EVENT SHALL ASUS, ITS
DIRECTORS, OFFICERS, EMPLOYEES OR AGENTS BE LIABLE FOR ANY INDIRECT, SPECIAL,
INCIDENTAL, OR CONSEQUENTIAL DAMAGES (INCLUDING DAMAGES FOR LOSS OF PROFITS,
LOSS OF BUSINESS, LOSS OF USE OR DATA, INTERRUPTION OF BUSINESS AND THE LIKE),
EVEN IF ASUS HAS BEEN ADVISED OF THE POSSIBILITY OF SUCH DAMAGES ARISING FROM ANY
DEFECT OR ERROR IN THIS MANUAL OR PRODUCT.
SPECIFICATIONS AND INFORMATION CONTAINED IN THIS MANUAL ARE FURNISHED FOR
INFORMATIONAL USE ONLY, AND ARE SUBJECT TO CHANGE AT ANY TIME WITHOUT NOTICE,
AND SHOULD NOT BE CONSTRUED AS A COMMITMENT BY ASUS. ASUS ASSUMES NO
RESPONSIBILITY OR LIABILITY FOR ANY ERRORS OR INACCURACIES THAT MAY APPEAR IN THIS
MANUAL, INCLUDING THE PRODUCTS AND SOFTWARE DESCRIBED IN IT.
Products and corporate names appearing in this manual may or may not be registered trademarks or
copyrights of their respective companies, and are used only for identication or explanation and to the
owners’ benet, without intent to infringe.
E15619
First Edition
August 2019

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Contents
Notices .......................................................................................................... 4
Safety information.......................................................................................... 9
Conventions used in this guide.................................................................... 10
Where to nd more information ................................................................... 10
Package contents ........................................................................................ 11
Chapter 1 Getting started
Welcome!..................................................................................................... 13
Getting to know your computer.................................................................... 13
Setting up your computer............................................................................. 19
Connecting multiple external displays ......................................................... 22
Turning your computer ON .......................................................................... 23
Chapter 2 Connecting devices to your computer
Connecting a USB storage device............................................................... 25
Connecting microphone and speakers ........................................................ 26
Changing to the external audio output......................................................... 29
Chapter 3 Using your computer
Proper posture when using your Desktop PC.............................................. 31
Using the optical drive (optional) ................................................................. 32
Conguring the USB ports using the BIOS.................................................. 33
Conguring the HDD security setting using the BIOS ................................. 34
Chapter 4 Connecting to the Internet
Wired connection......................................................................................... 35
Chapter 5 Troubleshooting
Troubleshooting........................................................................................... 37
Appendix Windows®10 User Manual
Starting for the rst time............................................................................... 47
Using the Windows®10 UI........................................................................... 48
Keyboard shortcuts...................................................................................... 52
ASUS contact information
ASUS contact information............................................................................ 54

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Notices
ASUS Recycling/Takeback Services
ASUS recycling and takeback programs come from our commitment to the highest standards
for protecting our environment. We believe in providing solutions for you to be able to
responsibly recycle our products, batteries, other components, as well as the packaging
materials. Please go to http://csr.asus.com/english/Takeback.htm for the detailed recycling
information in different regions.
REACH
Complying with the REACH (Registration, Evaluation, Authorisation, and Restriction of
Chemicals) regulatory framework, we published the chemical substances in our products at
ASUS REACH website at http://csr.asus.com/english/REACH.htm
Federal Communications Commission Statement
This device complies with Part 15 of the FCC Rules. Operation is subject to the following two
conditions:
• This device may not cause harmful interference; and
• This device must accept any interference received including interference that may cause
undesired operation.
This equipment has been tested and found to comply with the limits for a Class B digital
device, pursuant to Part 15 of the FCC Rules. These limits are designed to provide
reasonable protection against harmful interference in a residential installation. This
equipment generates, uses and can radiate radio frequency energy and, if not installed
and used in accordance with manufacturer’s instructions, may cause harmful interference
to radio communications. However, there is no guarantee that interference will not occur
in a particular installation. If this equipment does cause harmful interference to radio or
television reception, which can be determined by turning the equipment off and on, the user
is encouraged to try to correct the interference by one or more of the following measures:
• Reorient or relocate the receiving antenna.
• Increase the separation between the equipment and receiver.
• Connect the equipment to an outlet on a circuit different from that to which the receiver is
connected.
• Consult the dealer or an experienced radio/TV technician for help.
The use of shielded cables for connection of the monitor to the graphics card is required
to assure compliance with FCC regulations. Changes or modications to this unit not
expressly approved by the party responsible for compliance could void the user’s authority
to operate this equipment.
Lithium Battery Warning
CAUTION: Danger of explosion if battery is incorrectly replaced. Replace only with the
same or equivalent type recommended by the manufacturer. Dispose of used batteries
according to the manufacturer’s instructions.

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Compliance Statement of Innovation, Science and Economic
Development Canada (ISED)
This device complies with Innovation, Science, and Economic Development Canada licence
exempt RSS standard(s). Operation is subject to the following two conditions: (1) this device
may not cause interference, and (2) this device must accept any interference, including
interference that may cause undesired operation of the device:
Operation in the band 5150–5250 MHz is only for indoor use to reduce the potential for
harmful interference to co-channel mobile satellite systems; (3) for devices with detachable
antenna(s), the maximum antenna gain permitted for devices in the band 5250-5350 MHz
and 5470-5725 MHz shall be such that the equipment still complies with the e.i.r.p. limit.
CAN ICES-3(B)/NMB-3(B)
Déclaration de conformitéde Innovation, Sciences et Développement
économique Canada (ISED)
Le présent appareil est conforme aux CNR d’Innovation, Sciences et Développement
économique Canadaapplicables aux appareils radio exempts de licence. L’exploitation est
autorisée aux deux conditions suivantes : (1) l’appareil ne doit pas produire de brouillage,
et (2) l’utilisateur de l’appareil doit accepter tout brouillage radioélectrique subi, même si le
brouillage est susceptible d’en compromettre le fonctionnement.
La bande 5150 – 5250 MHz est réservée uniquement pour une utilisation à l’intérieur an de
réduire les risques de brouillage préjudiciable aux systèmes de satellites mobiles utilisant
les mêmes canaux; (3) pour les dispositifs munis d’antennes amovibles, le gain maximal
d’antenne permis pour les dispositifs utilisant les bande de 5 250 à 5 350 MHz et de 5 470 à
5 725 MHz doit être conforme à la limite de la p.i.r.e.
CAN ICES-3(B)/NMB-3(B)
IC: Canadian Compliance Statement
Complies with the Canadian ICES-003 Class B specications. This device complies with RSS
210 of Industry Canada. This Class B device meets all the requirements of the Canadian
interference-causing equipment regulations.
This device complies with Industry Canada license exempt RSS standard(s). Operation
is subject to the following two conditions: this device may not cause interference, and (2)
this device must accept any interference, including interference that may cause undesired
operation of the device.
Déclaration de conformitéd’Industrie Canada
Cet appareil numérique de la classe B est conforme à la norme NMB-003 du Canada.
Cet appareil numérique de la classe B respecte toutes les exigences du Règlement sur le
matériel brouilleur du Canada.
Le présent appareil est conforme aux normes CNR d’Industrie Canada applicables aux
appareils radio exempts de licence. Son utilisation est sujette aux deux conditions suivantes
Avertissement relatif aux batteries Lithium
ATTENTION ! Danger d’explosion si la batterie n’est pas correctement remplacée.
Remplacer uniquement avec une batterie de type semblable ou équivalent,
recommandée par le fabricant. Jeter les batteries usagées conformément aux
instructions du fabricant.

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: (1) cet appareil ne doit pas créer d’interférences et (2) cet appareil doit tolérer tout type
d’interférences, y compris celles susceptibles de provoquer un fonctionnement non souhaité
de l’appareil.
Canadian Department of Communications Statement
This digital apparatus does not exceed the Class B limits for radio noise emissions from
digital apparatus set out in the Radio Interference Regulations of the Canadian Department
of Communications.
This class B digital apparatus complies with Canadian ICES-003.
If protective earthing is used as a safeguard, the instructions shall requrie
connection of the equipment protective earthing conductor to the installation
protective earthing conductor (for example, by means of a power cord
conencted to a socket-outlet with earthing connection).
Branchez-le uniquement à une prise correctement câblée et mise à la terre.
VCCI: Japan Compliance Statement
VCCI Class B Statement
KC: Korea Warning Statement
RF Equipment Notices
CE: European Community Compliance Statement
The equipment complies with the RF Exposure Requirement 1999/519/EC, Council
Recommendation of 12 July 1999 on the limitation of exposure of the general public to
electromagnetic elds (0–300 GHz).
Wireless Radio Use
This device is restricted to indoor use when operating in the 5.15 to 5.25 GHz frequency
band.
Exposure to Radio Frequency Energy
The radiated output power of the Wi-Fi technology is below the FCC radio frequency
exposure limits. Nevertheless, it is advised to use the wireless equipment in such a manner
that the potential for human contact during normal operation is minimized.

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BSMI: Taiwan Wireless Statement
Japan RF Equipment Statement
KC (RF Equipment)
FCC Bluetooth Wireless Compliance
The antenna used with this transmitter must not be colocated or operated in conjunction with
any other antenna or transmitter subject to the conditions of the FCC Grant.
Bluetooth Industry Canada Statement
This Class B device meets all requirements of the Canadian interference-causing equipment
regulations.
Cet appareil numérique de la Class B respecte toutes les exigences du Règlement sur le
matériel brouilleur du Canada.

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India E-waste (Management and handling) Rule 2011
This product complies with the “India E-waste (Management and Handling)Rule 2011” and
prohibits use of lead, mercury, hexavalent chromium, polybrominated biphenyls(PBBs) and
polybrominated diphenyl ethers (PBDEs) in concentrations exceeding 0.1 % by weight in
homogenous materials and 0.01 % by weight in homogenous materials for cadmium, except
for the exemptions listed in Schedule-II of the Rule
AEEE Yönetmeliğine Uygundur
Optical Drive Safety Information
Laser Safety Information
WARNING! To prevent exposure to the optical drive’s laser, do not attempt to
disassemble or repair the optical drive by yourself. For your safety, contact a professional
technician for assistance.
Service warning label
WARNING! INVISIBLE LASER RADIATION WHEN OPEN. DO NOT STARE INTO BEAM
OR VIEW DIRECTLY WITH OPTICAL INSTRUMENTS.
CDRH Regulations
The Center for Devices and Radiological Health (CDRH) of the U.S. Food and Drug
Administration implemented regulations for laser products on August 2, 1976. These
regulations apply to laser products manufactured from August 1, 1976. Compliance is
mandatory for products marketed in the United States.
WARNING! Use of controls or adjustments or performance of procedures other than those
specied herein or in the laser product installation guide may result in hazardous radiation
exposure.
CD-ROM Drive Safety Warning
CLASS 1 LASER PRODUCT
The power cord shall connected to a socket-outlet with earthing connection.
Branchez-le uniquement à une prise correctement câblée et mise à la terre.

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ENERGY STAR is a joint program of the U.S. Environmental
Protection Agency and the U.S. Department of Energy helping
us all save money and protect the environment through energy
efficient products and practices.
All ASUS products with the ENERGY STAR logo comply with the
ENERGY STAR standard, and the power management feature is
enabled by default. The monitor and computer are automatically
set to sleep after 10 and 30 minutes of user inactivity. To wake
your computer, click the mouse or press any key on the keyboard.
Please visit http://www.energy.gov/powermanagement for detail information on power
management and its benefits to the environment. In addition, please visit http://www.
energystar.gov for detail information on the ENERGY STAR joint program.
*Note: Energy Star is NOT supported on Freedos and Linux-based products.
Safety information
Disconnect the AC power and peripherals before cleaning. Wipe the Desktop PC using a
clean cellulose sponge or chamois cloth dampened with solution of nonabrasive detergent
and a few drops of warm water then remove any extra moisture with a dry cloth.
• DO NOT place on uneven or unstable work surfaces. Seek servicing if the casing has
been damaged.
• DO NOT expose to dirty or dusty environments. DO NOT operate during a gas leak.
• DO NOT place or drop objects on top and do not shove any foreign objects into the
Desktop PC.
• DO NOT expose to strong magnetic or electrical elds.
• DO NOT expose to or use near liquids, rain, or moisture. DO NOT use the modem during
electrical storms.
• Battery safety warning: DO NOT throw the battery in re. DO NOT short circuit the
contacts. DO NOT disassemble the battery.
• Use this product in environments with ambient temperatures between 5˚C (41˚F) and
40˚C (104˚F).
• DO NOT cover the vents on the Desktop PC to prevent the system from getting
overheated.
• DO NOT use damaged power cords, accessories, or other peripherals.
• To prevent electrical shock hazard, disconnect the power cable from the electrical outlet
before relocating the system.
• Seek professional assistance before using an adapter or extension cord. These devices
could interrupt the grounding circuit.
• Ensure that your power supply is set to the correct voltage in your area. If you are not
sure about the voltage of the electrical outlet you are using, contact your local power
company.
• If the power supply is broken, do not try to x it by yourself. Contact a qualied service
technician or your retailer.

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Conventions used in this guide
To ensure that you perform certain tasks properly, take note of the following symbols used
throughout this manual.
DANGER/WARNING: Information to prevent injury to yourself when trying to
complete a task.
CAUTION: Information to prevent damage to the components when trying to
complete a task.
IMPORTANT: Instructions that you MUST follow to complete a task.
NOTE: Tips and additional information to help you complete a task.
Where to find more information
Refer to the following sources for additional information and for product and software
updates.
ASUS websites
The ASUS website provides updated information on ASUS hardware and software
products. Refer to the ASUS website www.asus.com.
ASUS Local Technical Support
Visit ASUS website at https://www.asus.com/support/contact for the contact information
of local Technical Support Engineer.

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Package contents
ASUS Desktop PC
D642MF / D6421SFF
Keyboard x1 (optional) Mouse x1 (optional)
Power cord x1 ASUS mouse pad x 1
(Optional)
Recovery DVD x1 (Optional)
Installation Guide
Warranty card x1 Installation Guide x1
• If any of the above items is damaged or missing, contact your retailer.
• The illustrated items above are for reference only. Actual product specications may
vary with different models.

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Welcome!
Thank you for purchasing the ASUS Desktop PC!
The ASUS Desktop PC provides cutting-edge performance, uncompromised reliability, and
user-centric utilities. All these values are encapsulated in a stunningly futuristic and stylish
system casing.
Read the ASUS Warranty Card before setting up your ASUS Desktop PC.
• The Desktop PC does not support Windows®7 operating system. ASUS is not
responsible for any loss or damage incurred by installing Window®7.
• Be careful when handling the desktop PC to prevent the risk of injury.
Getting to know your computer
ASUS Desktop PC 13
Chapter 1
Getting started

Front
Power button. Press this button to turn on your computer.
HDD LED. This LED shows the status of the hard disk drive.
Optical disk drive bay. There is an optical disk drive in this bay.
Optical disk drive eject button. Press this button to eject the optical disk drive
tray.
Illustrations are for reference only. The ports and their locations, the chassis and chassis
color vary with different models.
ab c d
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Option A:
a
USB 3.1 Gen 1 Type-A port
b
USB 3.1 Gen 1 Type-C port (5V/1.5A; for data transfer only)
c d
USB 2.0 ports
Option B:
a
b
USB 3.1 Gen 1 Type-A ports
c d
USB 2.0 ports
Option C:
a
b
c d
USB 3.1 Gen 1 Type-A ports
• DO NOT connect a keyboard / mouse to any USB 3.1 Gen1 port when installing
Windows®operating system.
• Due to USB 3.1 Gen1 controller limitation, USB 3.1 Gen1 devices can only be used
under Windows®OS environment and after the USB 3.1 Gen1 driver installation.
• USB 3.1 Gen1 devices can only be used as data storage only.
• We strongly recommend that you connect USB 3.1 Gen1 devices to USB 3.1 Gen1
ports for faster and better performance for your USB 3.1 Gen1 devices.
Headphone port. This port connects to a headphone or speaker. Supported by
ASUS Audio Wizard.
Microphone port. This port connects to a microphone.
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Rear
Power connector. Plug the power cord to this connector.
PS/2 mouse port. This port is for a PS/2 mouse.
PS/2 keyboard port. This port is for a PS/2 keyboard.
HDMI port. This port is for a High-Denition Multimedia Interface (HDMI)
connector, and is HDCP compliant allowing playback of HD DVD, Blu-ray, and
other protected content.
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DisplayPort. This port is for a DisplayPort-compatible device.
USB 3.1 Gen1 ports. These 9-pin Universal Serial Bus (USB) ports are for USB
3.1 Gen1 devices.
• DO NOT connect a keyboard / mouse to any USB 3.1 Gen1 port when installing
Windows®operating system.
• Due to USB 3.1 Gen1 controller limitation, USB 3.1 Gen1 devices can only be used
under Windows®OS environment and after the USB 3.1 Gen1 driver installation.
• USB 3.1 Gen1 devices can only be used as data storage only.
• We strongly recommend that you connect USB 3.1 Gen1 devices to USB 3.1 Gen1
ports for faster and better performance for your USB 3.1 Gen1 devices.
USB 2.0 ports. These Universal Serial Bus 2.0 (USB 2.0) ports connect to USB
2.0 devices such as a mouse, printer, scanner, camera, PDA, and others.
Microphone port (pink). This port connects to a microphone.
Line Out port (lime). This port connects to a headphone or speaker. In a 4.1, 5.1,
or 7.1-channel conguration, the function of this port becomes Front Speaker Out.
Supported by ASUS Audio Wizard.
Line In port (light blue). This port connects to a tape, CD, DVD player, or other
audio sources.
Refer to the audio conguration table below for the function of the audio ports in a 2.1,
4.1, 5.1, or 7.1-channel conguration.
Audio 2.1, 4.1, 5.1, or 7.1-channel configuration
Port Headset 2.1-channel 4.1-channel 5.1-channel 7.1-channel
Light Blue (Rear panel) Line In Rear Speaker Out Rear Speaker Out Rear Speaker Out
Lime (Rear panel) Line Out Front Speaker Out Front Speaker Out Front Speaker Out
Pink (Rear panel) Mic In Mic In Bass/Center Bass/Center
Front panel - - - Side Speaker Out
Expansion slot brackets. Remove the expansion slot bracket when installing an
expansion card.
LAN (RJ-45) port. This port allows Gigabit connection to a Local Area Network
(LAN) through a network hub.
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Activity/Link LED Speed LED
Status Description Status Description
OFF No link OFF 10Mbps connection
ORANGE Linked ORANGE 100Mbps connection
BLINKING Data activity GREEN 1Gbps connection LAN port
SPEED LED
ACT/LINK LED
LAN port LED indications
VGA port. This port is for VGA-compatible devices such as a VGA monitor.
Air vents. These vents allow air ventilation.
DO NOT block the air vents on the chassis. Always provide proper ventilation for your
computer.
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Setting up your computer
This section guides you through connecting the main hardware devices, such as the external
monitor, keyboard, mouse, and power cord, to your computer.
Connecting an external monitor
Using the ASUS Graphics Card (on selected models only)
Connect your monitor to the display output port on the discrete ASUS Graphics Card.
To connect an external monitor using the ASUS Graphics Card:
1. Connect a monitor to a display output port on the ASUS Graphics Card.
2. Plug the monitor to a power source.
The display output ports on the ASUS Graphics Card may vary with different models.
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Using the onboard display output ports
Connect your monitor to the onboard display output port.
To connect an external monitor using the onboard display output ports:
1. Connect a VGA monitor to the VGA port or a DisplayPort monitor to the DisplayPort
port on the rear panel of your computer.
2. Plug the monitor to a power source.
• If your computer comes with an ASUS Graphics Card, the graphics card is set as the
primary display device in the BIOS. Hence, connect your monitor to a display output port
on the graphics card.
• To connect multiple external monitors to your computer, refer to Connecting multiple
external display in Chapter 1 of this guide for details.
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