AXIOMTEK MANO521 Series User manual

MANO521 Series
Intel®Socket 1151 CoreTM i7/ i5/ i3
Processors Mini ITX Motherboard
User’s Manual

ii
Disclaimers
This manual has been carefully checked and believed to contain accurate information.
Axiomtek Co., Ltd. assumes no responsibility for any infringements of patents or any third
party’s rights, and any liability arising from such use.
Axiomtek does not warrant or assume any legal liability or responsibility for the accuracy,
completeness or usefulness of any information in this document. Axiomtek does not make any
commitment to update the information in this manual.
Axiomtek reserves the right to change or revise this document and/or product at any time
without notice.
No part of this document may be reproduced, stored in a retrieval system, or transmitted, in
any form or by any means, electronic, mechanical, photocopying, recording, or otherwise,
without the prior written permission of Axiomtek Co., Ltd.
CAUTION
If you replace wrong batteries, it causes the danger of explosion. It is recommended by the
manufacturer that you follow the manufacturer’s instructions to only replace the same or
equivalent type of battery, and dispose of used ones.
Copyright 2019 Axiomtek Co., Ltd.
All Rights Reserved
June 2019, Version A1
Printed in Taiwan

iii
ESD Precautions
Computer boards have integrated circuits sensitive to static electricity. To prevent chipsets
from electrostatic discharge damage, please take care of the following jobs with precautions:
Do not remove boards or integrated circuits from their anti-static packaging until you are
ready to install them.
Before holding the board or integrated circuit, touch an unpainted portion of the system
unit chassis for a few seconds. It discharges static electricity from your body.
Wear a wrist-grounding strap, available from most electronic component stores, when
handling boards and components.
Trademarks Acknowledgments
Axiomtek is a trademark of Axiomtek Co., Ltd.
Intel®and Celeron®are trademarks of Intel Corporation.
Windows®is a trademark of Microsoft Corporation.
AMI is a trademark of American Megatrend Inc.
IBM, PC/AT, PS/2, VGA are trademarks of International Business Machines Corporation.
Other brand names and trademarks are the properties and registered brands of their
respective owners.

iv
Table of Contents
Disclaimers ......................................................................................................ii
ESD Precautions............................................................................................. iii
Chapter 1 Introduction............................................. 1
1.1 Features................................................................................................1
1.2 Specifications........................................................................................2
1.3 Utilities Supported.................................................................................3
1.4 Block Diagram.......................................................................................4
Chapter 2 Board and Pin Assignments.................... 5
2.1 Board Layout.........................................................................................5
2.2 Rear I/O.................................................................................................7
2.3 Jumper Settings....................................................................................8
2.3.1 COM2 Data/Power Select (JP1) ................................................................. 9
2.3.2 Audio Output Select (JP2) (Optional).......................................................... 9
2.3.3 LVDS VDD Select (JP3).............................................................................. 9
2.3.4 Clear CMOS (JP4) .................................................................................... 10
2.3.5 Case Open Select (JP5) ........................................................................... 10
2.3.6 AT/ATX Power Mode Select (JP6) ............................................................ 10
2.4 Connectors..........................................................................................11
2.4.1 DC Jack Power Connector (CN1) ............................................................. 12
2.4.2 USB 2.0 Stack Port (CN2)......................................................................... 12
2.4.3 USB 3.0 Stack Port (CN3)......................................................................... 12
2.4.4 Ethernet Ports (CN4 and CN5) ................................................................. 13
2.4.5 COM1 D-Sub Connector (CN6) ................................................................ 13
2.4.6 Audio Jack (CN7)...................................................................................... 14
2.4.7 DisplayPort and HDMI Connector (CN8) .................................................. 14
2.4.8 ATX Power Input Connector (CN9)........................................................... 15
2.4.9 GPIO Header (CN10)................................................................................ 15
2.4.10 CMOS Battery Connector (CN11)............................................................. 15
2.4.11 VGAWafer Connector (CN12).................................................................. 16
2.4.12 Front Audio Connector (CN14).................................................................. 16
2.4.13 M.2 Key E Connector (CN15) ................................................................... 17
2.4.14 mSATA/Mini Card Connector (CN16)........................................................ 18
2.4.15 PCI-Express x4 Slot (CN17) ..................................................................... 19
2.4.16 USB 3.0 Wafer Connector (CN18)............................................................ 20
2.4.17 USB 2.0 Wafer Connector (CN19)............................................................ 20
2.4.18 Fan Connectors (CN21 and CN22)........................................................... 20
2.4.19 COM2 Wafer Connector (CN27)............................................................... 21

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2.4.20 LVDS Backlight Control Header (CN28) ................................................... 21
2.4.21 LVDS Signal Header (CN29)..................................................................... 22
2.4.22 SATA Power Connectors (CN30 and CN31)............................................. 22
2.4.23 SATA 3.0 Combo Connector (CN32)......................................................... 23
2.4.24 Front Panel Connector (CN34) ................................................................. 23
2.4.25 M.2 Key M Connector (CN35)................................................................... 24
2.4.26 SIM Card Slot (CN36) ............................................................................... 25
2.4.27 eDP Connector (CN37) (Optional) ............................................................ 26
Chapter 3 Hardware Description ........................... 27
3.1 Microprocessors..................................................................................27
3.2 BIOS....................................................................................................27
3.3 System Memory..................................................................................27
Chapter 4 AMI BIOS Setup Utility .......................... 29
4.1 Starting................................................................................................29
4.2 Navigation Keys..................................................................................29
4.3 Main Menu ..........................................................................................31
4.4 Advanced Menu..................................................................................32
4.5 Chipset Menu......................................................................................46
4.6 Security Menu .....................................................................................52
4.7 Boot Menu...........................................................................................53
4.8 Save & Exit Menu................................................................................55
Appendix A Watchdog Timer................................... 57
A.1 About Watchdog Timer........................................................................57
A.2 Sample Program .................................................................................57
Appendix B Configuring SATA for RAID .................. 59
B.1 Configuring SATA Hard Drive(s) for RAID Function.............................59
Appendix C iAMT Settings ...................................... 67
C.1 Entering MEBx....................................................................................67
C.2 Set and Change Password..................................................................67
C.3 iAMT Settings......................................................................................69
C.4 iAMT Web Console .............................................................................72
Appendix D TPM Settings........................................ 75

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MANO521 Mini ITX Motherboard
Introduction 1
Chapter 1
Introduction
The MANO521 Mini-ITX motherboard supports the new 14nm 8th Generation Intel®Core™ i7/
i5/ i3 and Pentium®processors in LGA1151 package. Featuring the new Intel®H310 Express
chipset with two DDR4 2666MHz memory support, this motherboard is built to perform best
stability and reliability for industrial applications.
It comes with two SATA 3.0, four USB 3.0, four USB 2.0 and two serial ports (one
RS-232/422/485, one RS-232) providing robust storage and I/O options. Users also can
increase board functionality with PCI-Express x4 and mSATA slot. The high quality MANO521
allows four display interfaces via HDMI, DisplayPort, VGA and LVDS in quadruplicate views,
making it an ideal solution for gaming, workstation, digital signage, medical and other
IoT&M2M applications.
1.1 Features
LGA1151 Socket for 8th Generation Intel®Core™ i7/ i5/ i3 and Pentium®processors
(Coffee Lake)
2 DDR4 2400/2666MHz memory with maximum capacity up to 32 GB
1 PCI-Express x4
1 PCI-Express Mini Card and 1 SIM card slots (support SATA, USB 2.0 signal, PCIE x1)
1 M.2 Key E, size: 22x30 for WiFi (support PCIE x1, USB 2.0 signal)
1 M.2 Key M (support SATA, PCIE x2 signal)
2 SATA-600
4 USB 3.0 and 4 USB 2.0

MANO521 Mini ITX Motherboard
2 Introduction
1.2 Specifications
CPU
LGA1151 Socket for 8th Generation Intel®Core™ i7/ i5/ i3 and Pentium®processors.
Chipset
Intel®H310/Q370 (optional).
BIOS
AMI BIOS via SPI interface.
System Memory
Two 260-pin SO-DIMM sockets.
Maximum up to 32GB DDR4 memory.
Support 2400/2666MHz.
Onboard Multi I/O
Controller: ITE8625.
Two serial ports:
- COM1 supports RS-232/422/485; COM2 supports RS-232 only.
- COM1 on the rear I/O; COM2 in wafer connector.
USB Interface
Two USB 3.0 ports (on the rear I/O).
Two USB 2.0 ports (on the rear I/O).
Two USB 3.0 ports in wafer connector (internal).
Two USB 2.0 ports in wafer connector (internal).
Ethernet
LAN1: 1000/100/10Mbps Gigabit/Fast Ethernet supports Wake-on-LAN, PXE with
Intel®i211AT.
LAN2: 1000/100/10Mbps Gigabit/Fast Ethernet supports Wake-on-LAN, PXE with
Intel®i219V/i219LM (optional).
Serial ATA
Two SATA 3.0 ports (6Gb/s).
One mSATA/Mini Card slot.
One M.2 Key M slot.
Audio
Realtek ALC662 5.1 channel HDA codec.
Support line-out (on the rear I/O).
Support MIC-in/line-out/line-in in box header (internal).
Display
One VGA connector in wafer connector. Resolution max. up to 1920x1200.
One HDMI with resolution max. up to 3840x2160 @30Hz.
One DisplayPort++ with resolution max. up to 4096x2304 @60Hz.
One 18/24-bit dual channel LVDS and one 8-pin inverter connector. LVDS resolution
is max. up to 1920x1200.
One Embedded DisplayPort (eDP) with resolution max. up to 4096x2304 @60Hz;
co-layout with LVDS (optional).

MANO521 Mini ITX Motherboard
Introduction 3
Expansion Interface
One PCI-Express x4 slot.
One PCI-Express Mini Card slot.
One M.2 key M slot.
One M.2 Key E slot.
One SIM card slot.
Power Input
One 12V,19~24V ATX 4-pin power input connector.
One 12V,19~24V DC jack power input connector.
Operating Temperature
0°C ~ 60°C.
Storage Temperature
-20°C ~ 65°C.
Form Factor
Mini ITX (6.7”x 6.7”, 17.0cm x 17.0cm).
Note
All specifications and images are subject to change without notice.
1.3 Utilities Supported
Chipset driver
Graphics driver
Intel ME driver
Ethernet driver
Audio driver
Chipset_serialio driver
Intel_Rapid_Storage_Technology driver

MANO521 Mini ITX Motherboard
4 Introduction
1.4 Block Diagram

MANO521 Mini ITX Motherboard
Board and Pin Assignments 5
Chapter 2
Board and Pin Assignments
2.1 Board Layout
Top View

MANO521 Mini ITX Motherboard
6 Board and Pin Assignments
Bottom View

MANO521 Mini ITX Motherboard
Board and Pin Assignments 7
2.2 Rear I/O
Jumpers/Headers/Connectors
1
Audio Output Select Jumper (JP2)
(Optional)
19
System Fan Connector (CN22)
2
Front Audio Connector (CN14)
20
USB 3.0 Wafer Connector ( CN18)
3
mSATA/Mini Card Connector (CN16)
21
USB 2.0 Wafer Connector ( CN19)
4
PCI-Express x4 Slot (CN17)
22
ATX Power Input 90 Angle Connector
(CN9) (Co-layout with 180 Angle
Connector, CN38)
5
M.2 Key E Connector (CN15)
23
GPIO Header (CN10)
6
CPU Fan Connector (CN21)
24
CMOS Battery Connector (CN11)
7
DDR4 SO-DIMM Connectors (CN23,
CN24)
25
VGA Wafer Connector (CN12)
8
Case Open Select Jumper (JP5)
26
DC Jack Power Connector (CN1)
9
AT/ATX Power Mode Select Jumper (JP6)
27
USB 2.0 Stack Port (CN2)
10
Clear CMOS Jumper (JP4)
28
USB 3.0 Stack Port (CN3)
11
Front Panel Connector (CN34)
29
Ethernet Ports (CN4, CN5)
12
SATA 3.0 Combo Connector (CN32)
30
COM1 D-Sub Connector (CN6)
13
SATA Power Connectors (CN30, CN31)
31
DisplayPort and HDMI Connector (CN8)
14
LVDS Signal Header (CN29)
32
Audio Jack (CN7)
15
LVDS Backlight Control Header (CN28)
33
M.2 Key M Connector (CN35)
16
COM2 Wafer Connector (CN27)
34
SIM Card Slot (CN36)
17
LVDS VDD Select Jumper (JP3)
35
eDP Connector (CN37)
18
COM2 Data/Power Select Jumper (JP1)

MANO521 Mini ITX Motherboard
8 Board and Pin Assignments
Note
To identify the first pin of a header or jumper, please refer to the following
information:
Usually, there is a thick line or a triangle near the header or jumper pin 1.
2.3 Jumper Settings
Jumper is a small component consisting of jumper clip and jumper pins. Install jumper clip on 2
jumper pins to close. And remove jumper clip from 2 jumper pins to open. The following
illustration shows how to set up jumper.
Before applying power to MANO521 Series, please make sure all of the jumpers are in factory
default position. Below you can find a summary table of all jumpers and onboard default
settings.
Note
Once the default jumper setting needs to be changed, please do it under power-off
condition.

MANO521 Mini ITX Motherboard
Board and Pin Assignments 9
Jumper
Description
Setting
JP1
COM2 Data/Power Select
Default: RS-232 Data
CN27 Pin 1: DCD#
3-5 Close
CN27 Pin 8: RI#
4-6 Close
JP2 (Optional)
Audio Output Select
Default: Line-out
1-3, 2-4 Close
JP3
LVDS VDD Select
Default: +3.3V
1-2 Close
JP4
Clear CMOS
Default: Normal Operation
1-2 Close
JP5
Case Open Select
Default: Close
1-2 Close
JP6
AT/ATX Power Mode Select
Default: ATX Mode
1-2 Close
2.3.1 COM2 Data/Power Select (JP1)
The COM2 port has +5V level power capability on DCD# and +12V level on RI# by
setting JP1.
2.3.2 Audio Output Select (JP2) (Optional)
Use this jumper to select line-out or speaker out as source for audio output on audio
connector. If speaker out is used, it will deliver 2W/channel continuous at 8Ωloads.
2.3.3 LVDS VDD Select (JP3)
The motherboard supports voltage selection for flat panel displays. Use this jumper to
set up VDD power of the LVDS connector. To prevent hardware damage, before
connecting please make sure that the input voltage of LVDS panel is correct.
Function
Setting
Power: Set CN27 pin 1 to +5V level
1-3 close
Data: Set CN27 pin 1 to DCD# (Default)
3-5 close
Power: Set CN27 pin 8 to +12V level
2-4 close
Data: Set CN27 pin 8 to RI# (Default)
4-6 close
Function
Setting
Line-out (Default)
1-3, 2-4 close
Speaker out
3-5, 4-6 close
Function
Setting
+3.3V (Default)
1-2 close
+5V
3-4 close
+12V
5-6 close

MANO521 Mini ITX Motherboard
10 Board and Pin Assignments
2.3.4 Clear CMOS (JP4)
This jumper allows you to clear the Real Time Clock (RTC) RAM in CMOS. You can
clear the CMOS memory of date, time, and system setup parameters by erasing the
CMOS RTC RAM data. The onboard button cell battery powers the RAM data in CMOS,
which includes system setup information such as system passwords.
To erase the RTC RAM:
1. Turn OFF the computer and unplug the power cord.
2. Remove the onboard battery.
3. Move the jumper clip from pins 1-2 (default) to pins 2-3. Keep the clip on pins 2-3
for about 5~10 seconds, then move the clip back to pins 1-2.
4. Re-install the battery.
5. Plug the power cord and turn ON the computer.
6. Hold down the <Del> key during the boot process and enter BIOS setup to re-enter
data.
2.3.5 Case Open Select (JP5)
Use this jumper for chassis intrusion detection feature.
2.3.6 AT/ATX Power Mode Select (JP6)
Use this jumper to select AT or ATX power mode.
Function
Setting
Normal operation (Default)
1-2 close
Clear CMOS
2-3 close
Function
Setting
Close (Default)
1-2 close
Active case open
1-2 open
Function
Setting
ATX mode (Default)
1-2 close
AT mode
2-3 close

MANO521 Mini ITX Motherboard
Board and Pin Assignments 11
2.4 Connectors
Signals go to other parts of the system through connectors. Loose or improper connection
might cause problems, please make sure all connectors are properly and firmly connected.
Here is a summary table showing connectors on the hardware.
Connector
Description
CN1
DC Jack Power Connector
CN2
USB 2.0 Stack Port
CN3
USB 3.0 Stack Port
CN4
Ethernet LAN1 Port (i211AT)
CN5
Ethernet LAN2 Port (i219V)
CN6
COM1 D-Sub Connector
CN7
Audio Jack
CN8
DisplayPort (Upper) and HDMI (Lower) Connector
CN9/CN38
ATX Power Input 90 Angle Connector. Co-layout with a
180 Angle Connector, CN38 (Optional)
CN10
GPIO Header
CN11
CMOS Battery Connector
CN12
VGA Wafer Connector
CN14
Front Audio Connector
CN15
M.2 Key E Connector
CN16
mSATA/Mini Card Connector
CN17
PCI-Express x4 Slot
CN18
USB 3.0 Wafer Connector
CN19
USB 2.0 Wafer Connector
CN21~CN22
Fan Connectors
CN23~CN24
DIMM1~DIMM2 DDR4 SO-DIMM Connectors
CN27
COM2 Wafer Connector
CN28
LVDS Backlight Control Header
CN29
LVDS Signal Header
CN30~CN31
SATA Power Connectors
CN32
SATA 3.0 Combo Connector
CN34
Front Panel Connector
CN35
M.2 Key M Connector
CN36
SIM Card Slot
CN37 (Optional)
eDP Connector

MANO521 Mini ITX Motherboard
12 Board and Pin Assignments
2.4.1 DC Jack Power Connector (CN1)
The CN1 is a DC jack with screw supporting 12V,
19~24VDC power input connector. Firmly insert at
least 90W adapter into this connector. Loose
connection may cause system instability and make
sure all components/devices are properly installed
before connecting.
Note
Screw metric thread size: M8.0x0.75.
2.4.2 USB 2.0 Stack Port (CN2)
The motherboard comes with one stacked Universal Serial Bus (compliant with USB 2.0)
connector on the rear I/O for installing USB peripherals such as keyboard, mouse,
scanner, etc.
2.4.3 USB 3.0 Stack Port (CN3)
The motherboard comes with one stacked Universal Serial Bus (compliant with USB 3.0)
connector on the rear I/O for installing USB peripherals such as keyboard, mouse,
scanner, etc.
Pin
Signal
Pin
Signal
1
USB_PWR
2
USB_PWR
3
USB#5_D-
4
USB#6_D-
5
USB#5_D+
6
USB#6_D+
7
GND
8
GND
Pin
Signal
Pin
Signal
1
USB_PWR
10
USB_PWR
2
USB#1_D-
11
USB#2_D-
3
USB#1_D+
12
USB#2_D+
4
GND
13
GND
5
SSRX1-
14
SSRX2-
6
SSRX1+
15
SSRX2+
7
GND
16
GND
8
SSTX1-
17
SSTX2-
9
SSTX1+
18
SSTX2+

MANO521 Mini ITX Motherboard
Board and Pin Assignments 13
2.4.4 Ethernet Ports (CN4 and CN5)
The motherboard comes with two high performance plug and play Ethernet interfaces
(RJ-45) which are fully compliant with the IEEE 802.3 standard. Connection can be
established by plugging one end of the Ethernet cable into this RJ-45 connector and the
other end to a 1000/100/10-Base-T hub.
CN4 CN5
CN4: LAN1 with Intel®
i211AT
CN5: LAN2 with Intel®
i219V
Note
Speed LED turns orange for 1000Mbps or green for 100Mbps.
Both CN4 and CN5 support Wake-on-LAN. When the motherboard
chipset is Intel®Q370, CN5 (LAN2) is changed to i219LM and with
AMT supported.
2.4.5 COM1 D-Sub Connector (CN6)
This connector is a standard D-Sub connector for COM1 serial port interface which is
selectable for RS-232/422/485 mode by BIOS setting (see section 4.4). The pin
assignments of RS-232/422/485 are listed in table below.
Pin
1000
Base-T
100/10
Base-T
Description
L1
BI_DA+
TX+
Bidirectional or Transmit Data+
L2
BI_DA-
TX-
Bidirectional or Transmit Data-
L3
BI_DB+
RX+
Bidirectional or Receive Data+
L4
BI_DC+
N.C.
Bidirectional or Not Connected
L5
BI_DC-
N.C.
Bidirectional or Not Connected
L6
BI_DB-
RX-
Bidirectional or Receive Data-
L7
BI_DD+
N.C.
Bidirectional or Not Connected
L8
BI_DD-
N.C.
Bidirectional or Not Connected
A
Active Link LED (Yellow)
Off: No link
Blinking: Data activity detected
B
Speed LED
1000: Orange
100/10: Green/OFF
Pin
RS-232
RS-422
RS-485
1
DCD#
TX-
Data-
2
RXD
TX+
Data+
3
TXD
RX+
N/C
4
DTR#
RX-
N/C
5
GND
GND
GND
6
DSR#
N/C
N/C
7
RTS#
N/C
N/C
8
CTS#
N/C
N/C
9
RI#
N/C
N/C

MANO521 Mini ITX Motherboard
14 Board and Pin Assignments
DisplayPort
HDMI
2.4.6 Audio Jack (CN7)
The motherboard provides HD audio jack for line-out on the rear I/O. Install audio driver,
and then attach audio devices to CN7.
2.4.7 DisplayPort and HDMI Connector (CN8)
The CN8 is a stacked connector comprising an upper connector for DisplayPort++
interface and a lower connector for HDMI interface.
Pin Color
Signal
Green
Line-out
Pin
Signal
Pin
Signal
1
DP_TX0_P
21
HDMI OUT_DATA2+
2
GND
22
GND
3
DP_TX0_N
23
HDMI OUT_DATA2-
4
DP_TX1_P
24
HDMI OUT_DATA1+
5
GND
25
GND
6
DP_TX1_N
26
HDMI OUT_DATA1-
7
DP_TX2_P
27
HDMI OUT_DATA0+
8
GND
28
GND
9
DP_TX2_N
29
HDMI OUT_DATA0-
10
DP_TX3_P
30
HDMI OUT_Clock+
11
GND
31
GND
12
DP_TX3_N
32
HDMI OUT_Clock-
13
GND
33
NC
14
GND
34
NC
15
DP_AUXP
35
HDMI OUT_SCL
16
GND
36
HDMI OUT_SDA
17
DP_AUXN
37
GND
18
DP_HPD
38
+5V
19
GND
39
HDMI_HTPLG
20
+3.3V