BRAINTRONICS BRAINBOX EEG-1142 User manual

BRAINBOX®EEG-1142
BRAINTRONICS B.V.
Gildemark 130
1351 HL ALMERE
The Netherlands
Phone : [phone]
Fax.: [phone]
Internet: http://www.braintronics.nl
email: [e-mail]
File name 860150 V1.10.doc
USERS MANUAL
EEG AMPLIFIER FOR EPILEPSY MONITORING
BRAINBOX®EEG-1142

USERS MANUAL BRAINBOX®EEG-1142 Rev. 1.10 Publ. 860150
BRAINTRONICS B.V Gildemark 130 1351 HL ALMERE THE NETHERLANDS
Phone [phone]Fax: [phone] email: [e-mail] internet: http://www.braintronics.nl Page 2 of 47
File name: 860150 V1.10.doc
Table of contents
Chapter Description Page
1GENERAL .........................................................................................5
1.1 Point of attention.............................................................................................................5
1.2 Introduction.....................................................................................................................5
1.3 Features.........................................................................................................................6
1.4 References.....................................................................................................................7
1.5 Guarantee ......................................................................................................................8
1.6 Document status.............................................................................................................8
2SAFETY ASPECTS...........................................................................9
2.1 General warnings ...........................................................................................................9
2.2 Symbols .........................................................................................................................9
2.3 Maintenance.................................................................................................................11
2.3.1 Cleaning of the instrument............................................................................................11
2.3.2 Repair and Modification................................................................................................11
2.4 Handling precautions....................................................................................................11
2.5 Operator skills ..............................................................................................................11
2.5.1 Operator Profile............................................................................................................12
2.6 Connections .................................................................................................................13
2.6.1 General information regarding mating of connectors ....................................................13
2.6.2 Power supply for the BRAINBOX®EEG-1142 .............................................................13
2.6.3 Ground connections .....................................................................................................14
2.6.4 Connection to other equipment.....................................................................................14
2.6.5 Restriction of use of the BRAINBOX®ETHERNET SYSTEM .......................................15
2.6.6 Cables..........................................................................................................................15
2.7 Environment.................................................................................................................15
2.7.1 Patient environment and applied part ...........................................................................16
2.8 End of life disposal .......................................................................................................17
3PLACE IN SYSTEM.........................................................................18
3.1 BRAINBOX®ETHERNET SYSTEM overview..............................................................18
3.2 System Features using the BRAINBOX®EEG-1142....................................................19
3.3 System input using the BRAINBOX®EEG-1142..........................................................20
3.4 Parts to use with BRAINBOX®EEG-1142....................................................................20
3.4.1 Touchproof input boxes................................................................................................ 20
3.5 Ground Reference Electrode........................................................................................21
3.6 Input Protection ............................................................................................................21
3.7 Operating modes..........................................................................................................21
3.7.1 EEG mode....................................................................................................................22
3.7.2 CAL mode ....................................................................................................................22
3.7.3 KOHM mode................................................................................................................. 24
3.7.4 System Characteristics mode (firmware V0.2 and higher) ............................................24
4SPECIFICATIONS...........................................................................25
4.1 General ........................................................................................................................25
4.2 Safety...........................................................................................................................25
4.2.1 Safety provided by the total BRAINBOX®ETHERNET SYSTEM .................................25
4.2.2 Safety provided by BRAINBOX®EEG-1142 ................................................................25
4.3 EMI Protection..............................................................................................................25

USERS MANUAL BRAINBOX®EEG-1142 Rev. 1.10 Publ. 860150
BRAINTRONICS B.V Gildemark 130 1351 HL ALMERE THE NETHERLANDS
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4.4 Inputs ...........................................................................................................................26
4.5 Calibration (For high accuracy see par. 4.9).................................................................26
4.6 Electrode check............................................................................................................27
4.7 Continuous KOhm range output ...................................................................................27
4.8 EEG Amplifiers (For high accuracy see par. 4.9)..........................................................27
4.9 High accuracy EEG channels....................................................................................... 28
4.10 CMRR, practical Common Mode Rejection Ratio .........................................................28
4.11 A/D Conversion EEG channels..................................................................................... 29
4.12 Digital FIR filter EEG channels .....................................................................................29
4.13 DC Amplifiers ...............................................................................................................29
4.14 A/D Conversion DC channels....................................................................................... 30
4.15 Interface (BRAINBUS)..................................................................................................30
4.16 System characteristics..................................................................................................30
4.17 Electromagnetic compatibility .......................................................................................31
4.18 Environment.................................................................................................................31
5CONNECTIONS..............................................................................32
5.1 EEG-signal inputs and GND references .......................................................................32
5.2 SpO2 and EVENT input................................................................................................33
5.2.1 SpO2 and EVENT output..............................................................................................34
5.3 BRAINBUS...................................................................................................................34
5.4 BRAINBUS Terminating Connector..............................................................................35
6DIRECTIONS FOR SOFTWARE DEVELOPMENT .........................36
6.1 Control code................................................................................................................. 36
6.2 Calibration Mode ..........................................................................................................37
6.3 EEG Mode....................................................................................................................38
6.4 Electrode Impedance Check.........................................................................................38
6.5 Channel definition.........................................................................................................40
7GUIDANCE ON ELECTROMAGNETIC COMPATIBILITY...............41
7.1 Guidance and manufacturers declaration .....................................................................41
7.1.1 Electromagnetic emissions...........................................................................................41
7.1.2 Electromagnetic immunity.............................................................................................42
7.2 General guidelines to avoid EMC problems..................................................................44
7.2.1 Disturbance caused by 50/60 Hz. mains voltage ..........................................................44
7.2.2 Precautions to prevent electromagnetic disturbances...................................................44
7.2.3 What to do if you need to make an EEG in a bad environment.....................................45
Appendix A. Characteristics of Digital FIR filter in all BRAINBOX®amplifiers............................. 46

USERS MANUAL BRAINBOX®EEG-1142 Rev. 1.10 Publ. 860150
BRAINTRONICS B.V Gildemark 130 1351 HL ALMERE THE NETHERLANDS
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Table of figures
Figure Description Page
Figure 1: Patient environment. ........................................................................................................................ 16
Figure 2: General block diagram BRAINBOX®ETHERNET SYSTEM........................................................... 18
Figure 3: Internal functions of System Components for 1 amplifier system.................................................... 19
Figure 4: Photo of BRAINBOX®EEG-1142 with INBOX-1142....................................................................... 20
Figure 5: Level CAL step response of EEG amplifier...................................................................................... 23
Figure 6: Overshoot on Level CAL signal........................................................................................................ 23
Figure 7: BRAINBOX®EEG-1142 EEG electrode connector......................................................................... 33
Figure 8: BRAINBOX®EEG-1142 EVENT, SpO2 and BRAINBUS connectors............................................ 33
Figure 9: SpO2 and EVENT inputs seen form outside.................................................................................... 34
Figure 10: BRAINBUS connectors seen from outside.................................................................................... 34
Figure 11: Diagram of the Impedance test signal............................................................................................ 39
Figure 12: Frequency vs. Gain response of analog input plus AA filter and digital filter................................. 47
Table of tables
Table Description Page
Table 1: Electrode input connector pin description ......................................................................................... 32
Table 2: Connector layout EVENT connector.................................................................................................. 33
Table 3: Connector layout SpO2 connector. ................................................................................................... 33
Table 4: Connector layout BRAINBUS. .......................................................................................................... 34
Table 5: BRAINBUS Terminating Connector.................................................................................................. 35
Table 6: Control Bytes for the BRAINBOX®EEG-1142 amplifier................................................................... 36
Table 7: Mode bits definitions.......................................................................................................................... 37
Table 8: Values of Electrode Test Level.......................................................................................................... 37
Table 9: Values of Amplifier Test Level........................................................................................................... 37
BRAINBOX®is a registered trademark of BRAINTRONICS.

USERS MANUAL BRAINBOX®EEG-1142 Rev. 1.10 Publ. 860150
BRAINTRONICS B.V Gildemark 130 1351 HL ALMERE THE NETHERLANDS
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1 GENERAL
1.1 Point of attention
The BRAINBOX® EEG-1142 is always to be used in combination with other Braintronics equipment to form a
BRAINBOX® ETHERNET SYSTEM. This cannot act as a complete EEG system, and always has to be used
with a PC with EEG analysis software not delivered by Braintronics BV, this manual is written from the
perspective of the System Integrator. The System Integrator therefore has to include all information needed
by the End User in his own user manuals. Special attention has to be given to all safety aspects and EMC
requirements included in this manual. Also see paragraph 1.4 for references to other manuals to be used for
system configuration, installation and software development.
1.2 Introduction
THE PERFECT FRONT END FOR EPILEPSY MONITORING
The BRAINBOX®EEG-1142 is part of a family of EEG amplifiers all having their own specific area of
application. The BRAINBOX®EEG-1142 amplifier is the perfect choice as front-end for computer based
small EEG systems, especially for ambulatory monitoring of epilepsy patients and polysomnography. The
system is designed for OEM users who market EEG analysis software and need an EEG amplifier front-end
to complete the EEG system. Braintronics can supply all BRAINBOX®equipment with a customized text
plate with name and logo’s as required.
HIGH END PERFORMANCE
The BRAINBOX®EEG-1142 is always to be used with a PC and EEG analysis software which are not
delivered by Braintronics BV. For interfacing to a standard Ethernet 10/100 Mbit LAN, Braintronics BV
delivers the ETHERNET-102 interface. For isolation Braintronics BV delivers the ISO-101. These system
parts together with all necessary cables form the BRAINBOX®ETHERNET SYSTEM. Additional to the
excellent performance of the EEG amplifier, the BRAINBOX®ETHERNET SYSTEM brings you features not
easily found in such a very compact system: Real Input Calibration, Electrode Impedance Check, excellent
digital filtering and anti aliasing of –40 dB at ½ sample rate. The small amplifier box with its thin flexible cable
makes it easy for the patient to move around freely during long term monitoring.
16 BIT AD CONVERTER BUILT IN
The BRAINBOX®EEG-1142 uses a 16 bit AD Converter for each EEG-channel. Assuring high quality
parallel sampling for all channels at the same time to prevent phase shifts between channels. The sample
rate of the ADC is 32768 Hz for the EEG channels of a BRAINBOX®amplifier, a 32x over sampling. DC
channels are sampled at a high 1024 Hz rate. In a daisy chained system simultaneous sampling of all
channels is also maintained.
LOW SENSITIVITY TO NOISE
Thanks to its high input isolation, the BRAINBOX®amplifiers are extremely insensitive to noisy
environments. The floating inputs give a very high rejection against common mode signals like 50/60 Hz.
interference. To further reduce 50/60 Hz interference under difficult noise situations, an active common mode
suppression system (G1/G2) is available.
FAST RECOVERY
The EEG amplifiers in the BRAINBOX®EEG-1142 are designed to have a fast recovery time when the
electrodes are first connected and also when disturbances occur due to electrode movement.
INPUT ISOLATION
The ultra portable BRAINBOX®EEG-1142 amplifiers do not have input isolation themselves. The isolation of
the total system is performed by the ISO-101. Total input isolation is according to EN60601-1, class II, and
type CF.
EMC PROTECTION
All parts of the BRAINBOX®EEG-1142 are shielded inside, all inputs are filtered for high frequency
interference and all inputs have a protection circuit against electrostatic discharge (ESD).

USERS MANUAL BRAINBOX®EEG-1142 Rev. 1.10 Publ. 860150
BRAINTRONICS B.V Gildemark 130 1351 HL ALMERE THE NETHERLANDS
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SIMPLE INTERFACING TO ANY PC BASED PLATFORM
The separate ETHERNET-102 Interface contains a complete TCP/IP protocol stack to communicate in a
simple way with a PC-application, based on a WINDOWS socket protocol. No extra hardware inside the PC
is needed.
FLEXIBILITY
A BRAINBOX® ETHERNET SYSTEM is easily adaptable to the users need. From a simple 32 channel EEG
only system up to a full 256 channel system. Furthermore features as DC channels, SpO2 handling, EVENT,
general digital I/O, LED impedance indication and Photic stimulation, are possible with specific BRAINBOX®
devices.
COMPLIANCE WITH THE MEDICAL DEVICE DIRECTIVE
The BRAINBOX®EEG-1142 is designed to comply fully with the Medical Device Directive 93/42/EEC of the
European Community.
45 YEARS OF EXPERIENCE
The design of the BRAINBOX®EEG-1142 is based on more than 45 years of experience in the field of
Neurophysiology.
1.3 Features
FULLY SOFTWARE CONTROLLED
The design of the BRAINBOX®ETHERNET SYSTEM is optimized for maximum convenience and the best
possible efficiency during use: it is fully remote controlled from the operator PC screen. This means you can
Check Electrodes, switch the amplifier input to a Calibration Voltage, select the amplitude of the calibration,
change the sample rate of the interface, etc., from inside the application software. All the communication is
done over an ETHERNET-LAN by using Braintronics proprietary protocol on top of the TCP/IP protocol.
LOW PRICE
The price of the BRAINBOX®ETHERNET SYSTEM is low enough to be interesting even when only 32
channels will actually be used.
LOW NOISE
The BRAINBOX®EEG-1142 amplifier has input amplifiers with FET (Field Effect Transistor) inputs. The
use of FET inputs makes sure that the amplifier not only has a low noise during calibration, but also in the
practical situation, with electrodes having a higher source impedance. The very low current noise of the FET
keeps the total noise low.
LOW INPUT BIAS CURRENT
The use of an FET input stage for the EEG amplifiers also guarantees a very low Input Bias Current. This is
the Amplifier DC input current-flow through the electrode. A very low Input Bias Current allows the use of
high impedance electrodes such as very small electrodes.

USERS MANUAL BRAINBOX®EEG-1142 Rev. 1.10 Publ. 860150
BRAINTRONICS B.V Gildemark 130 1351 HL ALMERE THE NETHERLANDS
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1.4 References
860071.doc
User information for the active GND reference system
860129.doc
Software manual ETHERNET-102
860141.doc
Software manual BRAINBOX®EEG-1166
860142.doc
Software manual FLASH-201
860143.doc
Software manual BRAINBOX®EEG-1042
860144.doc
Software manual BRAINBOX®EEG-1142
860148.doc
Software manual BRAINBOX®EEG-1164
860135.doc
User manual BRAINBOX®ETHERNET SYSTEM
860147.doc
User manual BRAINBOX®EEG-1164
860149.doc
User manual BRAINBOX®EEG-1166
860150.doc
User manual BRAINBOX®EEG-1142
860151.doc
User manual BRAINBOX®EEG-1042
860167.doc
User manual FLASH-201

USERS MANUAL BRAINBOX®EEG-1142 Rev. 1.10 Publ. 860150
BRAINTRONICS B.V Gildemark 130 1351 HL ALMERE THE NETHERLANDS
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1.5 Guarantee
All our instruments are guaranteed for 3 years against factory defects. Within the guarantee period,
instruments or parts of instruments are repaired in our factory free of charge if all transport costs are paid by
the customer.
Guarantee does not apply to parts which are normally exposed to wear or when a defect or malfunction is
caused by improper use and/or handling by unskilled people.
This product is designed and manufactured by BRAINTRONICS B.V. in The Netherlands and its quality and
performance are based on more than 45 years of experience in the field of EEG equipment.
Specifications and illustrations are not binding and subject to change without notice.
1.6 Document status
Copyright: Braintronics BV
Document identification: 860150.doc
Document status : Published
Revision: V1.10
Publishing date: 2018-11-15

USERS MANUAL BRAINBOX®EEG-1142 Rev. 1.10 Publ. 860150
BRAINTRONICS B.V Gildemark 130 1351 HL ALMERE THE NETHERLANDS
Phone [phone]Fax: [phone] email: [e-mail] internet: http://www.braintronics.nl Page 9 of 47
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2 SAFETY ASPECTS
2.1 General warnings
ALWAYS READ THE WHOLE MANUAL BEFORE USING THE BRAINBOX
®
ETHERNET SYSTEM
DO NOT INSTALL SUBSTITUTE PARTS OR PERFORM ANY UNAUTHORIZED MODIFICATION TO THIS
PRODUCT.
RETURN THIS PRODUCT TO BRAINTRONICS FOR SERVICE AND REPAIR TO ENSURE THAT
SAFETY FEATURES ARE MAINTAINED.
BE AWARE THAT THE BRAINBOX
®
EEG-1142 NEEDS SPECIAL PRECAUTIONS REGARDING EMC
AND NEEDS TO BE INSTALLED AND PUT INTO SERVICE ACCORDING TO THE EMC INFORMATION
GIVEN IN THIS MANUAL IN PARAGRAPH 7.
READ THE POINT OF ATTENTION IN PARAGRAPH 1.1
WHEN USED AS PART OF THE BRAINBOX
®
ETHERNET SYSTEM, THE BRAINBOX
®
EEG-1142
PROVIDES ELECTRICAL SAFETY AT EN60601-1 CF LEVEL. IT IS THE RESPOSIBILITY OF THE USER
TO MAINTAIN THE SAFETY LEVEL IF THE CONNECTED PC IS WITHIN REACH OF THE PATIENT
SPECIFIC WARNINGS ARE INDICATED IN THE TEXT WITH BOLD TEXT WARNING, FOLLOWED BY A
DESCRIPTION OF THE WARNING.
2.2 Symbols
Symbol for
EN60601-1 class II
Symbol for
EN60601-1
CF applied part
Symbol for “Attention:
Consult accompanying
documents"
0344
Symbol for
“Conformité
European” with
notified body
identification
Symbol for "Attention:
Observe precautions for
handling ESD sensitive
Devices"
Symbol for
Manufacturing year.
EN980:2003

USERS MANUAL BRAINBOX®EEG-1142 Rev. 1.10 Publ. 860150
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Symbol for
Manufacturer
EN980:2003
Symbol for separate
collection of electric
and electronic waste
Symbol for operating
instructions
ISO 7000-1641
Symbol for
connector mating
direction

USERS MANUAL BRAINBOX®EEG-1142 Rev. 1.10 Publ. 860150
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2.3 Maintenance
Normally spoken the BRAINBOX®EEG-1142 uses no specific maintenance apart from normal cleaning and
repair in case of defects.
To check if the BRAINBOX®EEG-1142 functions properly, the tests mentioned below can be carried out.
Performing these tests, the operator can, with sufficient training and competence, assess if the BRAINBOX®
EEG-1142 including its accessories functions correctly.
Real Input calibration of the electrode inputs. (see paragraph 3.7.2)
Electrode impedance check. (see paragraph 3.7.3)
These tests shall be performed regularly on a routine base.
Parts and especially cables that are found to be damaged or defective shall not be used any longer and must
be returned for repair or disposed of.
2.3.1 Cleaning of the instrument
The BRAINBOX®EEG-1142 shall NEVER be immersed in water or any other fluid. For cleaning, only use a
lightly moist tissue. If the instrument is too dirty to clean this way, an authorized technician should clean the
parts of the system and open the boxes (if possible) and ONLY the outer plastic parts should be cleaned in
water with a detergent, dried thoroughly, and reassembled.
2.3.2 Repair and Modification
Repair, modification and replacement of parts shall be done only by authorized people to maintain
compliance with the Medical Device Directive 93/42/EEC and the International Standards as mentioned in
paragraph Fout! Verwijzingsbron niet gevonden..
Upon request all necessary technical information regarding schematics, part lists, text plates, etc. will be
made available.
The manufacturer will never take responsibility for such action, even in case the manufacturer has given
suggestions or examples in any form of communication. In case of any doubt regarding safety, the complete
system or parts of the system shall be returned to the manufacturer.
When repair requires the inner box of the BRAINBOX®EEG-1142 to be opened observe the following:
-Take sufficient precautions to prevent ESD damage.
- Re-assemble parts the same way they were disassembled.
2.4 Handling precautions
Although the BRAINBOX®EEG-1142 internally has a very strong construction, care should be taken not to
drop, throw or damage the instruments mechanically in any way (this goes for any electronic instrument).
Special care should be taken regarding cables and plugs, also to have their life extended. If any doubt arises
on the integrity of the instrument as a whole or cable connections, return them to the manufacturer for proper
examination and repair if necessary. Cables that show damage should always be replaced.
2.5 Operator skills
The operator of an EEG Amplifier shall have the proper skills. The BRAINBOX®EEG-1142 is a sensitive
electronic instrument and shall be handled as such. Good care shall be taken for the environment in which
the patient is hooked up to the amplifier, especially in a multi-instrument environment.

USERS MANUAL BRAINBOX®EEG-1142 Rev. 1.10 Publ. 860150
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It is of utmost importance that the operator is aware of the standards applicable to this instrument, to be sure
not to degrade the level of safety the total system is designed for: by connecting a subject simultaneously to
other equipment of a lower safety class, the level of protection offered by the BRAINBOX®EEG-1142 as
part of the BRAINBOX®ETHERNET SYSTEM is degraded as well.
2.5.1 Operator Profile
From the perspective of Braintronics, the intended operator should have the following capabilities:
a) Education:
For EEG examinations where Electrical stimulation is used:
- At least a medical education as physician in the field of neurology involved in the treatment of
patients suffering from epilepsy
For all other EEG examinations:
- at least a medical education as EEG laboratory assistant
b) Knowledge:
For EEG examinations where no electrical stimulation is used:
- minimum:
read and understand the commonly used labelling of EEG equipment;
can apply standard EEG electrodes in the proper position on the skull of a patient;
is aware what influence the choice of the used EEG electrode and its material has on the
signal integrity of the recorded EEG signal;
can connect the used EEG electrodes to the proper connections of the BRAINBOX®
ETHERNET SYSTEM;
can apply other transducers, as commonly used in the field of application, to the patient;
can connect other transducers, as commonly used in the field of application, to the proper
connections of the BRAINBOX®ETHERNET SYSTEM;
can interconnect the separate parts of the BRAINBOX®ETHERNET SYSTEM to form one
front-end;
is aware of the sensitive nature of the used connectors on the interconnecting cables and
knows the procedures used for proper mating and disconnection of the different connectors.
understands the sensitive nature of EEG equipment regarding EMC
can discern a proper EEG signal, as represented on the visual display delivered by the
SYSTEM INTEGRATOR, from an EEG signal that is not good. Elements to consider are:
50 Hz or 60 Hz mains interference
muscle signals and movement artefacts
discontinuity of signals
can discern EEG signal quality as function of EEG electrode-skin contact if needed with the
aid of the IMP function;
can discern defect EEG channels by using the CAL function;
can discern a disconnected BRAINBOX®ETHERNET SYSTEM;
can discern a disconnected patient (some end-user implementations allow the patient to
disconnect from the system by disconnection of the BRAINNET cable);
knows the difference of ISOLATED and NON-ISOLATED parts of the system;
is aware of the safety consequences of the use of other medical equipment connected to the
patient simultaneous with the BRAINBOX®ETHERNET SYSTEM;
is aware of the possibility to provoke an epileptic insult when a patient is subjected to light
flashes with a certain repetition frequency;
is aware of the consequences of the use of EEG equipment on an unattended patient during
an extended time period;
is able to properly instruct a patient whom is unattended monitored for extended periods of
time.
Is aware of the fact that a disruption of the supply mains results in a system that has to be re-
initialized.
For EEG examinations where electrical stimulation is used:
- additional to the elements above:

USERS MANUAL BRAINBOX®EEG-1142 Rev. 1.10 Publ. 860150
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can connect an electrical stimulator to the Switchbox-11256;
can discern the proper selection of EEG electrodes coupled to EEG channels that are used for
electrical stimulation by using the MARK function;
can discern proper stimulation by observation of the EEG channels selected for stimulation
during the actual stimulation;
is aware of the risks associated with improper placement of electrodes used for electrical
stimulation;
is aware of the risks associated with mix-up of electrode leads when electrical stimulation is
applied;
is aware of the risks associated with improper selection of electrodes located on the cortex or
in the brain.
It is the responsibility of the SYSTEM INTEGRATOR to adapt the User Profile to the specific
application the BRAINBOX®ETHERNET SYSTEM will be used for. Elements that could be added are
e.g. experience, language understanding etc.
2.6 Connections
When making connections to the BRAINBOX®EEG-1142 the following paragraphs shall be observed.
2.6.1 General information regarding mating of connectors
PUSH/PULL TYPE CONNECTORS
FOR MATING OF ALL INTERCONNECTING CABLES OF THE BRAINBOX®EEG-1142, FIRST
OBSERVE PROPER ALIGNMENT AND THEN ONLY INSERT USING A PUSHING DIRECTION.
FOR DISCONNECTION OF ALL INTERCONNECTING CABLES OF THE BRAINBOX®EEG-1142, ONLY
USE A PULLING DIRECTION
BAJONET TYPE CONNECTORS
FOR MATING OF THE POWER CONNECTOR AND THE SERIAL I/O CONNECTOR OF THE
ETHERNET-102(V2) FIRST OBSERVE PROPER ALIGNMENT, THEN INSERT WITH A PUSHING
DIRECTION FOLLOWED BY A CLOCKWISE ROTATION OF 45 DEGREES
FOR DISCONNECTION OF THE POWER CONNECTOR AND SERIAL I/O CONNECTOR FROM THE
ETHERNET-102(V2) FIRST USE AN ANTI CLOCKWISE ROTATION OF 45 DEGREES FOLLOWED
BY A PULLING DIRECTION
WHEN NOT PROPERLY HANDLED, DAMMAGE OF CONNECTORS CAN OCCUR
Except the power connector of the ETHERNET--102(V2) and the serial I/O connector of the ETHERNET-
102V2, all connectors used in the BRAINBOX® ETHERNET SYSTEM are PUSH/PULL type connectors.
The power connector and the serial I/O connector are of the bayonet type.
2.6.2 Power supply for the BRAINBOX®EEG-1142
The BRAINBOX®EEG-1142 is powered from the BRAINBOX®ETHERNET SYSTEM. The power is applied
to the ETHERNET-102 from an external medical grade mains adapter 21BA. This mains adapter is specified
as part of the BRAINBOX®ETHERNET SYSTEM. It may not be exchanged for another type.
Warning:
The mains adapter 21BA must be located in a way that quick disconnection is easy.
From the BRAINNET connection of the ETHERNET-102 (V2) the BRAINBUS ISOLATOR is powered. The
BRAINBUS ISOLATOR has a build-in 24V-DC/5V-DC converter. The safety specifications for this DC/DC
converter are according the requirements of IEC60601 class II type CF. From here the
BRAINBOX®EEG-1142 is powered over the BRAINBUS. The requirements for the externally applied power

USERS MANUAL BRAINBOX®EEG-1142 Rev. 1.10 Publ. 860150
BRAINTRONICS B.V Gildemark 130 1351 HL ALMERE THE NETHERLANDS
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supply for the BRAINBOX®ETHERNET SYSTEM can be found in “User manual
BRAINBOX®ETHERNET SYSTEM”, document 860135.doc.
Warning:
Be aware that when the mains power is disrupted for some time, the BRAINBOX®ETHERNET SYSTEM has
to be re-initialized. This includes it’s network connection, system configuration and operating mode. The
BRAINBOX®ETHERNET SYSTEM has no means to retain this information. When disruption from the mains
power for some given time is required, the System Integrator shall take precautions by installation of an UPS
in the total system. When automatic re-connection and re-initialization is required after a power disruption,
the operational settings have to be stored by the software of the System Integrator in the computer of the
System Integrator.
Warning:
Be aware that when the mains adapter 21BA is connected to a Multiple Socket-Outlet being part of the
complete system, that this Multiple Socket-Outlet leads to risks that the end user must be aware of. These
risks must be added to the end-user information by the System Integrator. The following risks shall be
addressed when Multiple Socket-Outlets are used:
- The risk to connect extra equipment that is not meant to be used together with the complete system.
- The risk to connect extra equipment leading to an overload of the Multiple Socket-Outlet.
- The risk that the Multiple Socket-Outlet is placed on the floor leading to vulnerability to mechanical
damage and ingress of fluids.
2.6.3 Ground connections
MAKE NO GROUND CONNECTION TO THE ELECTRODE INPUTS
All BRAINBOX®amplifiers have electrically floating inputs for safety. Never make any electrical connection
between any of the inputs, including the “R” marked reference and “G1/G2” marked active references, to a
safety ground, water-tap ground, ground of a shielding cage, construction metal, or any such conductors.
Otherwise the floating nature of the BRAINBOX®amplifier is destroyed. When an electrical connection from
the floating inputs to other conductors is made, the operator must be fully aware of the consequences and
shall do so according the applicable standards and regulations.
2.6.4 Connection to other equipment
ALL EQUIPMENT TO BE CONNECTED TO THE BRAINBOX®ETHERNET SYSTEM SHALL FULFILL
THE SAFETY REQUIREMENTS OF THE APPLICABLE STANDARDS
If other equipment is used in combination with the BRAINBOX®ETHERNET SYSTEM, it is of great
importance that the operator is fully aware of the consequences for safety and of course, signal integrity.
Connection to electrode inputs.
If a non-floating signal is connected to the floating input of a BRAINBOX®amplifier, the floating nature of the
BRAINBOX®ETHERNET SYSTEM is destroyed. If anything else then the patient is coupled to these inputs,
it shall provide sufficient isolation.
Connection to the digital I/O inputs on the ETHERNET-102 Interface.
The digital I/O signals are on the non-floating side of the BRAINBOX®ETHERNET SYSTEM. So connection
of external equipment to these signals does not compromise the floating nature of the patient coupled parts
of the BRAINBOX®ETHERNET SYSTEM. However if the connected equipment also has patient coupled
parts, these parts must be floating.
Be aware of the possibility that the BRAINBOX®ETHERNET SYSTEM can contribute to the total
leakage current of the patient if the BRAINBOX®ETHERNET SYSTEM is connected simultaneous with
other medical equipment to one patient.

USERS MANUAL BRAINBOX®EEG-1142 Rev. 1.10 Publ. 860150
BRAINTRONICS B.V Gildemark 130 1351 HL ALMERE THE NETHERLANDS
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If the floating nature of the BRAINBOX®ETHERNET SYSTEM is maintained, the expectation is that there
are not problems with using the BRAINBOX®ETHERNET SYSTEM simultaneous with a cardiac pacemaker.
2.6.5 Restriction of use of the BRAINBOX®ETHERNET SYSTEM
The BRAINBOX®ETHERNET SYSTEM does not have any protection regarding possible burning of the
patient which can take place as a result of the failure, absence or not sufficiently low impedance of the
neutral electrode of the high frequency (HF) surgical equipment. However if the
BRAINBOX®ETHERNET SYSTEM is used in combination with high frequency (HF) surgical, an extra
neutral electrode for the high frequency (HF) surgical equipment should be introduced on the patient to
reduce the risk of burning by failure of the high frequency (HF) surgical equipment.
2.6.6 Cables
The BRAINBOX®EEG-1142 shall be used with the cables as described in “User manual
BRAINBOX®ETHERNET SYSTEM”, document 860135.doc. The use of other cables can result in increased
RF radiation and/or decreased EMI immunity levels. Be aware that the BRAINBOX®cables are only to be
used as described. Always observe proper alignment and mating/disconnection directions.
2.7 Environment
NEVER USE THE BRAINBOX®ETHERNET SYSTEM IN AN ENVIRONMENT FOR WHICH IT IS NOT
DESIGNED TO BE USED IN.
The BRAINBOX®ETHERNET SYSTEM may only be used in a standard medical examination room in a
hospital.
Be aware that Medical Electrical Equipment needs special precautions regarding EMC and needs to be
installed and put into service according to the EMC information included in this document in paragraph 7.
Be aware that portable and mobile RF communications equipment can affect Medical Electrical
Equipment.
Be aware that normal operation of the BRAINBOX®ETHERNET SYSTEM should be observed when it is
to be used adjacent to or stacked with other equipment.
The BRAINBOX®ETHERNET SYSTEM is not to be used in an oxygen rich environment.

USERS MANUAL BRAINBOX®EEG-1142 Rev. 1.10 Publ. 860150
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2.7.1 Patient environment and applied part
The System Integrator defines the Patient Environment. From the perspective of Braintronics, the
BRAINBOX®ETHERNET SYSTEM was designed with the following patient environment in mind.
See Figure 1. From the perspective of Braintronics, the whole BRAINBOX®ETHERNET SYSTEM
can reside in the patient environment. This means all parts of the
BRAINBOX®ETHERNET SYSTEM can be touched by the patient.
Figure 1: Patient environment.
Applied part
What is to be considered to be the applied part of the BRAINBOX®ETHERNET SYSTEM ?
The definition of the applied part is that part in which makes direct contact with the patient or are
directly related with this. For the BRAINBOX®ETHERNET SYSTEM there are two possibilities:
1. For the large BRAINBOX®EEG-1042 amplifier we consider the complete amplifier being the
applied part.
2. For the small BRAINBOX®EEG-11xx amplifiers we consider the amplifier plus it’s compatible
INBOX-11xx as the applied part.
Parts that may be used in the patient environment
As described above all parts of the BRAINBOX®ETHERNET SYSTEM are expected to reside in
the patient environment. Other parts that may be used there are to be defined by the System
Integrator.

USERS MANUAL BRAINBOX®EEG-1142 Rev. 1.10 Publ. 860150
BRAINTRONICS B.V Gildemark 130 1351 HL ALMERE THE NETHERLANDS
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2.8 End of life disposal
For the disposal of the BRAINBOX®ETHERNET SYSTEM at the end of it’s life there are no
specific requirements other then what is required for disposal of normal electronic equipment. For
disposal the local directives are to be adhered to.

USERS MANUAL BRAINBOX®EEG-1142 Rev. 1.10 Publ. 860150
BRAINTRONICS B.V Gildemark 130 1351 HL ALMERE THE NETHERLANDS
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3 PLACE IN SYSTEM
3.1 BRAINBOX®ETHERNET SYSTEM overview.
To give more insight on the place of the BRAINBOX®EEG-1142 in the total system, this topic starts with a
short overview of the coherence of BRAINBOX® ETHERNET SYSTEM components. The
BRAINBOX®ETHERNET SYSTEM exists of a number of different components allowing a great number of
different configurations. Some insight in the function of the separate components gives a better
understanding and simplifies reading of this users manual. A schematic block diagram of a typical
BRAINBOX®ETHERNET SYSTEM with a maximum functionality can be seen in Figure 2. Systems with
less functionality and therefore less system components are also possible. The BRAINBOX®ETHERNET
SYSTEM is very flexible in this respect.
Figure 2: General block diagram BRAINBOX®ETHERNET SYSTEM
In this diagram, the following functional blocks and system specific elements can be recognized:
1
Touch proof connections for patient connection of the EEG leads.
2
Multipin connector for convenient connection of Electrode Caps.
3
One or more EEG amplifiers.
There are different amplifier types with different combinations of the following capabilities:
- EEG channels maximally 64 channels or 32 channels per amplifier.
- DC channels maximally 8 channels per amplifier.
- SpO2 input for NONIN X-POD pulse-oxi.
- EVENT input.
- Designed for ultra portability.
- Designed for routine stationary EEG measurements.
- Real input calibration.
- Electrode Impedance check.
- LED indication of Impedance check.
4
Inputs for SpO2 and EVENT handling.
5
A low voltage (5 V dc) BRAINBUS providing power and making use of the Braintronics proprietary
protocol for control and data acquisition of the system.
6
BRAINBUS daisy chainable with a short Bus Link.
7
BRAINBUS is terminated with a Termination connector.
8
An Isolator to separate the patient applied part from the mains connected PC.
9
A LED Photic Stimulator.
10
An Ethernet TCP/IP interface to connect to a standard 10/100 MB Ethernet LAN and used to control the
system and to transport the acquired data.
11
Two Medium voltage (24 V dc) BRAINNET busses providing power and making use of the Braintronics
proprietary protocol for control and data acquisition of the system.
12
General purpose Digital In- and Outputs, not isolated.
13
TCP/IP Ethernet 10/100 connection.
14
Mains adapter.
15
GND connection to suppress mains induced 50 or 60 Hz disturbances.

USERS MANUAL BRAINBOX®EEG-1142 Rev. 1.10 Publ. 860150
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A schematic example of the inner functions of the most important system parts can be seen in Figure 3.
Figure 3: Internal functions of System Components for 1 amplifier system.
In all BRAINBOX
®ETHERNET SYSTEM
configurations two BUSSES can be recognized. The
BRAINBUS and BRAINNET. These are local interfaces within the system. Only a high level
description with general characteristics of these interfaces is given. A specific description of the
used data protocol and functions of these two busses falls outside the scope of this user-manual.
The system is fully controlled by the proprietary Brainbox
®
protocol on top of the standard TCP/IP
protocol. The proprietary Brainbox
®
protocol is separately described in document 860129.doc.
An extensive description of the complete BRAINBOX®ETHERNET SYSTEM can be found in
document 860135.doc.
3.2 System Features using the BRAINBOX®EEG-1142
The BRAINBOX®EEG-1142 amplifier is an ideal front end for a digital EEG system, having the following
features:
32 Galvanic isolated (floating) Unipolar EEG inputs. (Extendable to 224 EEG inputs by using three extra
BRAINBOX®EEG-1166 amplifiers in Daisy Chain mode)
8 Galvanic isolated (floating) Unipolar DC inputs.
1 channel for SpO2. (NONIN X-Pod has to be added)
1 channel for EVENT. (EVENT button has to be added).
Digital data output to PC, no ADC in the PC is needed.
Real input calibration.
From version V0.2 of the embedded firmware, Sine wave and GND Calibration signals available.
Impedance check of electrodes on PC screen.
Simple interfacing by using Braintronics Proprietary protocol on top of the standard ETHERNET TCP/IP
protocol.
Ultra portable.
From version V0.2 of the embedded firmware, System characteristics output mode. Showing internal
voltages and administrative data like serial nr. production date etc.
From V0.3 of the embedded firmware the EEG channels can be calibrated in the factory for higher
accuracy.

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3.3 System input using the BRAINBOX®EEG-1142
The BRAINBOX®EEG-1142 amplifier has 32 inputs for EEG monitoring. The EEG inputs are available on a
68 pin connector that is present on the side of the BRAINBOX®EEG-1142 amplifier. This 68 pins connector
can be extended, by means of the INBOX-1142, to the Touchproof electrode connectors. There are two
types of INBOX-1142, identified with an Aor B. This allows a maximum of two BRAINBOX®EEG-1142
amplifiers in a system configuration while addition of two other amplifier types is still possible. The channel
identifications according to the international 10/20 system are printed on the text plate of the INBOX, see
Figure 4 for an example. It is very important to use the right INBOX. When the system is build up having two
BRAINBOX®EEG-1142 amplifiers, the user must be aware which channels correspond to a specific
amplifier. This is both defined by the specific INBOX and the used software definable configuration. Each
type of INBOX has its own unique BRAINBUS address code. Every BRAINBOX®EEG-1142 amplifier reads
this unique address code and takes care that its data is put in the right place in the data protocol of the
BRAINBUS and finally in the output data the PC application receives.
In one system, each BRAINBUS address may only be present one time, so always use different
INBOX types in a system with multiple amplifiers !!
3.4 Parts to use with BRAINBOX®EEG-1142
Apart from standard system parts, there are some elements designed specifically to be used together with
the BRAINBOX®EEG-1142.
3.4.1 Touchproof input boxes
There are several options for connecting EEG electrodes with standard Touchproof connectors.
For the BRAINBOX®EEG-1142, two types of input boxes with Touchproof connectors are available.
One type acts like a clip that is placed over the amplifier resulting in a very compact module with a
size of 9.5 x 11 x 3 cm. See Figure 4. All INBOXES are simple passive components only taking care of a
connection between Touchproof connectors and the multipin connector.
The following touchproof input boxes are available for the BRAINBOX®EEG-1142:
Stackable INBOX-1142 and Large INBOX-1042.
These inboxes are each available in 4 different address types.
Figure 4: Photo of BRAINBOX®EEG-1142 with INBOX-1142.