MannKind afrezza User manual

(
insulin human
)
Inhalation Powder
Quick Steps Guide
Learn key steps on how to use Afrezza®. For more details, please
see full Prescribing Information, including boxed WARNING,
Medication Guide, and Instructions for Use on Afrezza.com.
Step 1: Select the cartridge for the right dose.
Step 2: Load a cartridge.
4 Units:
If the Afrezza dose
is 4 units, use 1
blue cartridge.
8 Units:
If the Afrezza dose
is 8 units, use 1
green cartridge.
12 Units:
If the Afrezza dose
is 12 units, use 1
yellow cartridge.
If the prescribed Afrezza dose is more than 12 units,
you will need to use more than 1 cartridge to get the
right dose. Multiple inhalations will be necessary.
• Hold Inhaler: Hold the inhaler level in one hand with the white mouthpiece on the top and
purple base on the bottom.
• Open Inhaler: Open the inhaler by lifting the white mouthpiece to a vertical position.
• Place Cartridge: Hold the cartridge with the cup facing down. The pointed end of the
cartridge should line up with the pointed end in the inhaler. Place cartridge into the inhaler,
making sure it lies at in inhaler.
• Keep Level: Now that the cartridge is loaded, keep the inhaler level from this point forward
to avoid loss of drug powder. Do not turn it upside down, shake, or drop, as this could cause
a loss of drug powder.
• Close Inhaler: Lower the mouthpiece to close the inhaler (this will open the drug cartridge).
A snap should be felt when the inhaler is closed.
AFREZZA and the Afrezza and MannKind logos are registered marks, all owned by MannKind Corporation.
© MannKind Corporation 2018. US-AFR-0430

AFREZZA and the Afrezza and MannKind logos are registered marks, all owned by MannKind Corporation.
© MannKind Corporation 2018. US-AFR-0430
Step 3: Inhale insulin.
Step 4: Remove cartridge and discard.
• Remove Cover: Remove the mouthpiece cover. Keep the inhaler level.
• Exhale: Hold the inhaler away from mouth and exhale fully.
• Position Inhaler: Keeping head and inhaler level, place the mouthpiece in mouth. Close lips
around the mouthpiece to form a seal. Tilt the inhaler downward while keeping head level as
shown.
• Inhale Deeply and Hold Breath: With mouth closed around the mouthpiece, inhale deeply
through the inhaler. Hold breath for as long as comfortable and at the same time remove the
inhaler from mouth. Exhale and breathe normally.
• Replace Cover: Put the mouthpiece cover back onto the inhaler.
• Open Inhaler: Open the inhaler by lifting the white mouthpiece.
• Remove Cartridge: Remove the cartridge from the purple base.
• Discard: Throw away the cartridge in regular household trash.
Repeat steps 2 through 4 for each Afrezza cartridge needed for dose.
(
insulin human
)
Inhalation Powder