NantHealth HBox User manual

NANTHEALTH, LLC | 430 W. 5th Street Suite 800, Panama City, FL
32401 | Phone: 1.855.WHY.NANT | nanthealth.com
User Guide
HBox® 200-
HBV-PDL
v01.01.00-0

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Table of Contents
Table of Contents..................................................................................... 1
General Description ................................................................................. 3
Indications for Use................................................................................... 3
Intended Audience .............................................................................. 3
Client Support Contact Information .................................................... 4
Included in the HBox Package.................................................................. 5
Safety Information ................................................................................... 5
Caution Statement................................................................................... 6
HBox System Figures................................................................................ 6
HBox Set Up ............................................................................................. 8
Connecting Power................................................................................ 9
HBox Battery........................................................................................ 9
Master Reset Button............................................................................ 9
Indicator Lights ........................................................................................ 10
Power Indicator ................................................................................... 10
Connection to Server Indicator............................................................ 10
Data Transmission Indicator ................................................................ 10
Cellular Signal Strength Indicator ........................................................ 10
Vitality...................................................................................................... 11
Escalating Reminders ........................................................................... 11
Cloud Connected ................................................................................. 11
Remotely Programmable ..................................................................... 11
General Handling Instructions ................................................................. 11
General Cleaning.................................................................................. 11
IP Rating............................................................................................... 11

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HBox Specifications.................................................................................. 12
Regulatory information............................................................................ 14
Federal Communications Commission (FCC) ....................................... 14
FCC Radiation Exposure Statement ..................................................... 15
Important Handling Information ..................................................... 15
Disposal and Recycling Information......................................................... 15
Table of Figures........................................................................................ 15
Manufacturer Contact ......................................................................... 16

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Thank you for selecting the NANTHEALTH HBox. This user guide is
intended to serve as an aid in the proper set-up, installation, and
operation of the HBox device. We ask that you read this user guide
carefully before proceeding to work with the equipment for safe usage
of this product. Please retain this user guide available for ready
reference if needed.
General Description
HBox is a small, durable, medical-grade product platform supporting
device connectivity. It hosts NANTHEALTH’s software for sending data
from a wide range of data generating in-home medical devices to a
location accessible by the care team.
HBox extends NANTHEALTH connectivity to any location within
Verizon Wireless 3G cellular coverage. Connection to a devices is
supported via Bluetooth or USB for standalone devices to connect to
HBox via a Device Escort serial-to-USB converter cable. Measurement
data is thus delivered to the care team in near real-time.
Indications for Use
The NANTHEALTH HBox is intended for use in connecting medical
devices including Personal Health Devices (PHD) to a server for
transferring measurement data.
Intended Audience
The intended audience for this guide is any individual utilizing HBox in
the home for medical device connectivity. Target audiences are
general consumers, patient care technicians and/or assistants, nurses,
biomedical technicians and administrative IT personnel.

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Client Support Contact Information
NantHealth Client Support contact information and hours of
operation:
The support line hours are 24/7.
The number is 866-202-2124
Support can be accessed online at
www.nanthealth.com/

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Included in the HBox Package
Qty Item Part Number
1 HBox with Tabletop Bracket 200-HBV-PDL
1 AC/DC Power Supply Cable 100-HPS-PVL
HK-AD-050A500-US mfg
1 User Guide HBV-v01.01.00-0-
Operating_Instructions-R01
Safety Information
Symbol
Meaning
Manufacturer
Consult Operating Instructions
Serial Number
Wireless Module MEID Number for Cellular
Activation

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Caution Statement
CAUTION Do not attempt to plug in any devices to the HBox’s
USB port which are not intended to be used with the
HBox (i.e. USB storage devices).
CAUTION Do not use a power supply other than that provided
by NANTHEALTH.
CAUTION Do not attempt to remove or replace the HBox
internal battery. The lithium-ion battery in HBox
should be serviced only by NantHealth, and must be
recycled or disposed of separately from household
waste.
HBox System Figures
Connection to Server Indicator
Data Transmission Indicator
Power Indicator

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Figure 1: HBox Front Panel
Figure 2: HBox Side Panel
Reset Button
Signal Strength Indicator
Reset Button
Signal Strength Indicator
USB Ports
Vitality Reminder Light
Vitality Speaker
Ethernet Connection Port

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Figure 3: Rear and Bottom View
Figure 4: Removable Tabletop Bracket
HBox Set Up
Installation / Placement
Identify a location for HBox placement on a flat surface like a tabletop,
countertop, nightstand or desktop near to an AC power outlet. HBox
has a bracket with rubber feet which allows it to lay flat on a dry table.
Ethernet Indicator Light
Ethernet Indicator Light
AC Power Connector
Lift Up Tab for Removal
Slides Out
Power Supply Cable Inlet

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Assembly
Assemble the HBox by lifting up the tab on the Removable Tabletop
Bracket on the bottom of the HBox and sliding it out (Figure 4). Insert
the AC power connector into the barrel plug on the back of HBox and
rotate it 90 degrees so that the cord can be secured in the inlet, and
out of the way of the bracket (Figure 3).
Place the Removable Tabletop Bracket back on the device by sliding it
in. It will click into place. HBox should always be used with the
Removable Tabletop Bracket to hold the Power Supply cord in place.
Connecting Power
Plug in the AC power connector to a nearby electrical outlet.
HBox powers on and boots up automatically when it is plugged in. A
power button is not required. Once the HBox establishes connectivity,
it is ready for use. Follow any included Quick Start Guide materials for
setting up other devices to connect to HBox.
HBox Battery
The AC power should always remain connected. However, in the event
that AC power is disconnected, the internal lithium-ion battery
functions to assist in the safe shut down of the HBox and to finish any
in-progress data transmission.
Master Reset Button
The master reset button is for the purpose of rebooting the HBox in
the event it becomes unresponsive. The button is located inside the
plastic door on the side of HBox. When the door is opened, the master
reset button is accessible by paperclip or pin.
HBox will immediately power down when master reset button is
pressed. There is no need to wait for several seconds, the reset
happens right away.
HBox will begin normal startup when master reset button is
released (i.e. un-pressed).

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Indicator Lights
Power Indicator
Once powered on, and while in the process of booting, the power
indicator light on the forward face panel will blink green. After the
boot process completes, the power indicator light displays as solid
green, visible from a distance of up to 5 feet.
Connection to Server Indicator
Located on the face panel is a light that indicates server connection
status.
When connected to the server, the connection to server
indicator displays as green
When there is no connection to the server, the connection to
server indicator displays as blue
Data Transmission Indicator
HBox contains a single light on the face panel that indicates when data
is being transmitted from HBox to the server. When data is being
transmitted from HBox to the server, the data transmission indicator
light displays as blinking green.
Cellular Signal Strength Indicator
Located on the right side panel there are three signal strength bars
which indicate signal strength.
The first bar indicates the lowest signal strength.
The second bar indicates greater signal strength than the first
bar.
The third bar indicates the highest signal strength.
Figure 5: Signal Strength Indicator

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Vitality
Escalating Reminders
HBox uses light, then light + sound to subtly remind Vitality user using
the light bar on the front-center of HBox, (Figure 1).
Cloud Connected
Vitality wirelessly uploads its data to a secure data-center. No
separate computer or data-plan is required. Just plug in the HBox.
After pairing with HBox, Vitality will play a startup tone at power on
along with Vitality Reminder Light glowing orange which changes to
glowing blue.
Remotely Programmable
During scheduled dosage window, Vitality Reminder Light will blink
orange until medication is taken and the GlowCap or GlowPack is re-
closed.
General Handling Instructions
General Cleaning
HBox is water resistant and ingress protected (IP) and may be wiped
down or sterilized with alcohol or liquid cleaners that contain up to
10% bleach without degrading.
IP Rating
HBox has an IP rating of IP52
Vertically dripping water has no harmful effect when HBox is
tilted at an angle of up to 15° from its upright position
Note: Ingress of dust is not entirely preventable but will not interfere
with proper functioning of the device

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HBox Specifications
3G Cellular
Connectivity
3G CDMA (800 MHz and 1900 MHz)
Connectivity
HBox supports connectivity to a 3G
CDMA wireless networks with the
following standards:
•EV-DO Rev A
•EV-DO Rev 0
•IxRTT / IS-95A
Bluetooth
Connectivity
Bluetooth 4.0 Low Energy (BTLE)
Connectivity
USB
Connectivity
Built-In USB Port
•HBox USB ports are type A female
•USB ports are version 2.0
compliant
HBox connects two USB devices without
the need of a USB hub
Processing
Power
Processor Specifications
•32-bit ARM
•One core
•Clock speed of up to 1.0 GHz
Memory
•2 GB RAM
•8 GB solid state storage space
•Expandable Storage via internal
memory card
Vitality
Connectivity
Vitality GlowCap®, GlowPack™
communication uses specific channels in
900 MHz range.

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Operating
Temperature
•Range of +5 deg C to +40 deg C
•Range of +41 deg F to +104 deg F
Atmospheric
Pressure
•Range of 700 hPa to 1060 hPa
Storage
Temperature
•Range of -25 deg C to +70 deg C
•Range of -13 deg F to + 158 deg F
Humidity
•Range of 0% to 93% Relative
Humidity (RH), non-condensing

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Regulatory information
HBox is currently designed to meet regulations for use in the United
States only.
Federal Communications Commission (FCC)
FCC ID: IFU1001011 and contains FCC ID: QISMC509
This device complies with part 15, 22 and 24 of the Federal
Communications Commission (FCC) Rules.
Operation is subject to the following two conditions:
1. This device may not cause harmful interference.
2. This device must accept any interference received,
including interference that may cause undesired
operation.
Note: This equipment has been tested and found to comply with the
limits for a Class B digital device, pursuant to Part 15 of the FCC Rules.
These limits are designed to provide reasonable protection against
harmful interference in a residential installation. This equipment
generates uses and can radiate radio frequency energy and, if not
installed and used in accordance with the instructions, may cause
harmful interference to radio communications. However, there is no
guarantee that interference will not occur in a particular installation. If
this equipment does cause harmful interference to radio or television
reception, which can be determined by turning the equipment off and
on, the user is encouraged to try to correct the interference by one or
more of the following measures:
Increase the separation between the equipment and the receiver
Connect the equipment into an outlet on a circuit different from
that to which the receiver is connected
Consult the dealer or an experienced radio/TV technician for
help
Any changes or modifications not expressly approved by the
manufacturer could void the user’s authority to operate the
equipment.

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This device is restricted to indoor use only when operating in the 5.15
to 5.25 GHz frequency band (U-NII 1).
FCC Radiation Exposure Statement
The Equipment must be installed to provide a separation distance of at
least 7.9 inches (20cm) from all persons during operation, and must
not be co-located or operated in conjunction with any antenna or
transmitter subject to the conditions of the FCC Grant.
Important Handling Information
Only use the provided AC power cable to connect the power supply to
a main power outlet that is properly installed and grounded, in
accordance with all local codes and ordinances. If the power supply
cord is damaged, contact NantHealth for a replacement.
As a safety measure to prevent potential adverse results to data
transmission, users should not plug personal electronics into an HBox
USB port.
Disposal and Recycling Information
Dispose of HBox in accordance with the Standard Waste Procedures in
your geographic area. Ultimate disposal of this product should be
handled according to all national laws and regulations.
Because it contains a battery, HBox must be disposed of separately
from household waste. Contact your local authorities to learn about
recycling options.
Table of Figures
Figure 1: HBox Front Panel .................................................................... 6
Figure 2: HBox Side Panel ...................................................................... 7
Figure 3: HBox Rear and Bottom View................................................... 7

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Figure 4: Rear and Bottom View............................................................ 8
Figure 5: Signal Strength Indicator....................................................... 10
Manufacturer Contact
NantHealth, LLC
430 West 5th Street
Suite 800
Panama City, FL 32401
United States of America
www.nanthealth.com

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