OptiNose XHANCE User manual

INSTRUCTIONS FOR USE
2007377
Nosepiece
Tapered Tip
Bottle
Flexible
Mouthpiece
Indented
Grip
Cap
Step 1: Remove the Cap.
Step 2: Shake XHANCE (See Figure E).
Step 3: Hold XHANCE by placing your ngers on the Indented Grip
below the Flexible Mouthpiece. You can use 1 hand (See Figure F),
or 2 hands (See Figure G) to hold XHANCE.
Do not place your ngers above or over the Flexible Mouthpiece.
Priming XHANCE:
Step 1: Remove the Cap (See Figure C).
Step 2: Shake XHANCE.
Step 3: Press the Bottle 7 times or until you see a ne mist (See Figure D).
Keep the Tapered Tip of XHANCE pointed away from your face
while priming. When you see a ne mist of medicine, XHANCE is
ready to use.
Important: If you have not used XHANCE for 7 or more days, re-prime
by spraying 2 times away from your face.
One-handed Two-handed
Figure F
Original Version
Read these Instructions for Use before you start
using XHANCE and each time you get a refill.
There may be new information. This information
does not take the place of talking to your healthcare
provider about your medical condition or treatment.
If you have any questions about XHANCE, ask your
healthcare provider or pharmacist.
• XHANCE is for use in your nose only.
Do not spray in your eyes or mouth.
• XHANCE delivers your dose of medicine into
your nose when you press the Bottle while
blowing into the Flexible Mouthpiece
(See Figure B).
• Do not share XHANCE with other people.
• Shake XHANCE before each use.
• Do not block second nostril while blowing.
• Do not place fingers above or over the
Flexible Mouthpiece.
Figure B
Parts of XHANCE
Figure D
Figure C
Figure E
Figure G
Indented Grip Indented Grip
XHANCETM (ex hans’)
(uticasone propionate)
nasal spray,93 mcg
Figure A
Bottle
Flexible
Mouthpiece
Prime XHANCE before rst use
Steps for using XHANCE after priming
Important information about XHANCE
Steps continue on other side
Tapered Tip
Bottle

Step 8: While still blowing hard into the Flexible Mouthpiece, use
your thumb to press the Bottle to deliver medicine into
your nostril (See Figure L).
Step 7: Blow hard into the Flexible Mouthpiece like you are blowing
up a balloon (See Figure K).
Do not try to breathe in through your nose or sniff while
blowing into the Flexible Mouthpiece.
Do not close or block your other nostril. This could prevent
the air you blow into the Flexible Mouthpiece from leaving
out through the other nostril.
Step 6: Aim the device upward. This will help the medicine go deep into
your nostril (See Figure J).
Note: You can use a mirror to help you aim the device upward.
Step 5: Insert the Flexible Mouthpiece in your mouth, while keeping
the Nosepiece in your nostril (See Figure I). Make sure that the
Flexible Mouthpiece is secure in the mouth and the Nosepiece
remains sealed in the nostril during use.
Note: You can bend the Flexible Mouthpiece up and down to get
it into your mouth while keeping the Nosepiece deep in
your nostril.
Figure I
Figure K
Figure L
Figure M
Figure J
Figure H Step 4: Gently insert the Nosepiece into the nostril. While still holding
XHANCE on the Indented Grip below the Flexible Mouthpiece,
insert the Nosepiece as far back into 1 nostril as comfortable
(See Figure H). This helps to keep a tight seal between the
Nosepiece and your nostril.
Important: Keep a tight seal between the Nosepiece and your Nostril.
Step 9: Repeat Steps 2 through 8 in the “Steps for using
XHANCE after priming” to deliver the medicine
into your other nostril (See Figure M).
• Store at room temperature (between 15°C and 25°C; 59°F and 77°F).
• Protect XHANCE from light.
• Throw away XHANCE after using 120 sprays after initial priming. Even though the
Bottle may not be completely empty, you may not get the correct dose of medicine
if you continue to use it.
• You do not need to clean XHANCE. If you prefer to clean the device, remove the
Cap and use a clean, dry, lint-free cloth to wipe after each use.
• Replace the Cap and store XHANCE in a clean, dry place.
• The XHANCE Bottle is made of glass and can break if dropped or hit too hard.
If you accidentally drop XHANCE, check it for damage. Return it to your pharmacist
if the device is damaged or the Bottle is broken.
Keep XHANCE and all medicines out of the reach of children.
These Instructions for Use have been approved by the U.S. Food and Drug Administration.
Distributed by OptiNose US, Inc.
XHANCE and OPTINOSE are trademarks or registered trademarks of OptiNose AS.
©2017 OptiNose US, Inc. All rights reserved
Issued 09/2017
Did I do it right?
Shake before each use.
Keep a snug fit in nose
and mouth.
Continue blowing forcefully
while pressing the Bottle.
Do not sniff, inhale, or block
second nostril.
Administer only the
prescribed number of
sprays in each nostril.
Steps for using XHANCE after priming (cont’d)
Cleaning XHANCE
How should I store XHANCE?
For more information, please visit
www.XHANCE.com or call1.833.678.6673
Nosepiece
Flexible
Mouthpiece