Step 8: While still blowing hard into the Flexible Mouthpiece, use
your thumb to press the Bottle to deliver medicine into
your nostril (See Figure L).
Step 7: Blow hard into the Flexible Mouthpiece like you are blowing
up a balloon (See Figure K).
Do not try to breathe in through your nose or sniff while
blowing into the Flexible Mouthpiece.
Do not close or block your other nostril. This could prevent
the air you blow into the Flexible Mouthpiece from leaving
out through the other nostril.
Step 6: Aim the device upward. This will help the medicine go deep into
your nostril (See Figure J).
Note: You can use a mirror to help you aim the device upward.
Step 5: Insert the Flexible Mouthpiece in your mouth, while keeping
the Nosepiece in your nostril (See Figure I). Make sure that the
Flexible Mouthpiece is secure in the mouth and the Nosepiece
remains sealed in the nostril during use.
Note: You can bend the Flexible Mouthpiece up and down to get
it into your mouth while keeping the Nosepiece deep in
your nostril.
Figure I
Figure K
Figure L
Figure M
Figure J
Figure H Step 4: Gently insert the Nosepiece into the nostril. While still holding
XHANCE on the Indented Grip below the Flexible Mouthpiece,
insert the Nosepiece as far back into 1 nostril as comfortable
(See Figure H). This helps to keep a tight seal between the
Nosepiece and your nostril.
Important: Keep a tight seal between the Nosepiece and your Nostril.
Step 9: Repeat Steps 2 through 8 in the “Steps for using
XHANCE after priming” to deliver the medicine
into your other nostril (See Figure M).
• Store at room temperature (between 15°C and 25°C; 59°F and 77°F).
• Protect XHANCE from light.
• Throw away XHANCE after using 120 sprays after initial priming. Even though the
Bottle may not be completely empty, you may not get the correct dose of medicine
if you continue to use it.
• You do not need to clean XHANCE. If you prefer to clean the device, remove the
Cap and use a clean, dry, lint-free cloth to wipe after each use.
• Replace the Cap and store XHANCE in a clean, dry place.
• The XHANCE Bottle is made of glass and can break if dropped or hit too hard.
If you accidentally drop XHANCE, check it for damage. Return it to your pharmacist
if the device is damaged or the Bottle is broken.
Keep XHANCE and all medicines out of the reach of children.
These Instructions for Use have been approved by the U.S. Food and Drug Administration.
Distributed by OptiNose US, Inc.
XHANCE and OPTINOSE are trademarks or registered trademarks of OptiNose AS.
©2017 OptiNose US, Inc. All rights reserved
Issued 09/2017
Did I do it right?
Shake before each use.
Keep a snug fit in nose
and mouth.
Continue blowing forcefully
while pressing the Bottle.
Do not sniff, inhale, or block
second nostril.
Administer only the
prescribed number of
sprays in each nostril.
Steps for using XHANCE after priming (cont’d)
Cleaning XHANCE
How should I store XHANCE?
For more information, please visit
www.XHANCE.com or call1.833.678.6673
Nosepiece
Flexible
Mouthpiece
