Table of Contents
1Safety Notices ......................................................................................................................4
2Introduction .........................................................................................................................4
2.1 What is Open Platform User Specified (OPUS®)? ......................................................................4
2.2 Column Design ...........................................................................................................................4
2.3 Platformable ..............................................................................................................................5
2.4 Materials of Construction ..........................................................................................................5
2.5 OPUS® Physical Specifications ...................................................................................................7
2.6 Product Contact Materials.........................................................................................................8
2.7 Solvent Compatibility.................................................................................................................9
2.8 Column Mass Table..................................................................................................................10
2.9 OPUS® Column Handling..........................................................................................................10
3Preparing to Use Your OPUS® Column .................................................................................10
4OPUS® Column Sanitization, Storage, and Disposal.............................................................. 13
4.1 Cleaning and Sanitization Notes ..............................................................................................13
5Troubleshooting .................................................................................................................13
5.1 Air in the column......................................................................................................................13
5.2 High pressure during first use of column.................................................................................13
5.3 Pressure increase during run ...................................................................................................14
5.4 Pressure drop during run .........................................................................................................14
6Appendices.........................................................................................................................15
6.1 Appendix 1: Use of a 3-Way Valve for Inlet Connection and Air Purging................................15
6.2 Appendix 2: Connecting an OPUS® column to Chromatography Skids ...................................16
6.3 Appendix 3: Column Performance Testing ..............................................................................16
Index .........................................................................................................................................19
