Thermo Scientific 1370 User manual

arnstead Nanopure™
Life Science (UV/UF)
ultrapure water system
Operation Manual
Series 1370
Model o. Voltage
D11931 100V - 240V
L 1370X1 • 7/23/09

Safety Information ..........................................................................................................................................................................................3
Alert Signals ..........................................................................................................................................................................................3
Warnings................................................................................................................................................................................................3
Introduction ....................................................................................................................................................................................................5
General Usage ......................................................................................................................................................................................5
General Specifications ....................................................................................................................................................................................6
Environmental Conditions......................................................................................................................................................................7
Declaration of Conformity ......................................................................................................................................................................7
Unpacking ......................................................................................................................................................................................................8
Installation ......................................................................................................................................................................................................9
Choosing a Site ....................................................................................................................................................................................9
Ultrafilter Installation ............................................................................................................................................................................10
UV Lamp Installation ..........................................................................................................................................................................11
Other Accessories ..............................................................................................................................................................................11
ench Mounting ..................................................................................................................................................................................12
Wall Mounting ......................................................................................................................................................................................12
Installing the Control Panel in a Remote Location ..............................................................................................................................13
Water Connections ..............................................................................................................................................................................14
Tubing Installation ................................................................................................................................................................................15
Electrical Connections ........................................................................................................................................................................15
Controls ........................................................................................................................................................................................................16
Main Power Switch ..............................................................................................................................................................................16
Control Panel ......................................................................................................................................................................................16
Switches ..............................................................................................................................................................................................17
Initial Operation ............................................................................................................................................................................................18
Cartridge Pack Installation ..................................................................................................................................................................18
Initial Rinse ..........................................................................................................................................................................................19
System Cleaning Procedure................................................................................................................................................................20
Normal Operation..........................................................................................................................................................................................22
Dispensing Water ................................................................................................................................................................................22
Automatic Dispensing ..........................................................................................................................................................................22
User Settings ................................................................................................................................................................................................23
Adjusting Display rightness ..............................................................................................................................................................23
Setting the Displayed Language..........................................................................................................................................................23
Setting the Date and Time ..................................................................................................................................................................24
Setting the Cell Constant ....................................................................................................................................................................24
Use of Standby Mode..........................................................................................................................................................................26
Selecting the Set Point ........................................................................................................................................................................26
Resetting the Cleaning Timer ..............................................................................................................................................................27
Resetting the UV Timer ......................................................................................................................................................................27
Setting Volumetric Dispensing ............................................................................................................................................................28
Setting Timed Dispensing....................................................................................................................................................................29
Performing a System Flush ................................................................................................................................................................29
Changing Purity Units..........................................................................................................................................................................29
Temperature Compensation ................................................................................................................................................................30
Auto Standby ......................................................................................................................................................................................30
Unit Under Counter..............................................................................................................................................................................31
Accessories ..................................................................................................................................................................................................32
Float or Pressure Switch ....................................................................................................................................................................32
Dispense Overflow Cutoff Float ..........................................................................................................................................................33
Performing an Electronic Calibration Using the Optional N.I.S.T. Calibration Module ........................................................................34
Manual Remote Dispenser and Accu DIspense Volumetric Remote Dispenser ................................................................................35
Computer/Printer Setup ................................................................................................................................................................................36
Connecting Nanopure to Computer and Communicating Through the RS-232 Port Using Hyperterminal or Procomm ..................36
Connecting and Starting the Printer ....................................................................................................................................................38
Printer Setup........................................................................................................................................................................................39
Maintenance and Servicing ..........................................................................................................................................................................40
General Cleaning Instructions ............................................................................................................................................................40
Cell Cleaning ......................................................................................................................................................................................40
System Cleaning ................................................................................................................................................................................41
System Depressurization ....................................................................................................................................................................42
Cartridge Pack Replacement ..............................................................................................................................................................43
0.2 Micron Filter Replacement ............................................................................................................................................................44
Ultrafilter Replacement ........................................................................................................................................................................44
UV Lamp Replacement ......................................................................................................................................................................46
Fuse Replacement ..............................................................................................................................................................................47
Shutdown ............................................................................................................................................................................................47
Troubleshooting ............................................................................................................................................................................................48
Replacement Parts ......................................................................................................................................................................................51
Flow Chart ....................................................................................................................................................................................................53
Wiring Diagram ............................................................................................................................................................................................54
Ordering Procedures ....................................................................................................................................................................................55
Two Year Limited Warranty............................................................................................................................................................................56
Table of Contents

Your Thermo Scientific arnstead Nanopure Life Science
(UV/UF) ultrapure water system has been designed with
function, reliability, and safety in mind. It is your responsi-
bility to install it in conformance with local electrical
codes. This manual contains important safety information.
You must carefully read and understand the contents of
this manual prior to the use of this equipment. For safe
operation, please pay attention to the alert signals
throughout the manual.
Water purification technology employs one or more of the
following: chemicals, electrical devices, mercury vapor
lamps, steam and heated vessels. Care should be taken
when installing, operating or servicing Thermo Scientific
products. The specific safety notes pertinent to this
Thermo Scientific product are listed below.
Warnings
To avoid electrical shock, always:
1. Use a properly grounded electrical outlet of
correct voltage and current handling capacity.
2. Do not locate the Nanopure directly over equip-
ment that requires electrical service. Routine
maintenance of this unit may involve water
spillage and subsequent electrical shock hazard
if improperly located.
3. Replace fuses with those of the same type and
rating.
4. Disconnect from the power supply prior to main-
tenance and servicing.
To avoid personal injury:
1. Do not use in the presence of flammable or
combustible materials; fire or explosion may
result. This device contains components which
may ignite such materials.
2. This device is to be used with water feeds only.
Cleaning agents must be used in compliance
with instructions in this manual. Failure to com-
ply with the above could result in explosion and
personal injury.
3
Safety Information
Caution
Cautions alert you to a possibility of
damage to the equipment.
Warning
Warnings alert you to a possibility of
personal injury.
ote
Notes alert you to pertinent facts and
conditions.
Alert Signals
ote
The UV lamp contains mercury. If bro-
ken or no longer needed, do not dis-
pose of the UV lamp in the trash.
Recycle or dispose of the UV lamp as
hazardous waste.

3. Avoid splashing cleaning solutions on clothing or
skin.
4. Ensure all piping connections are tight to avoid
chemical leakage.
5. Ensure adequate ventilation.
6. Carefully follow manufacturer’s safety
instructions on labels of chemical containers and
material safety data sheets.
7. Depressurize system prior to removing the
cartridge pack.
8. This unit is equipped with an ultraviolet lamp.
Ultraviolet radiation is harmful to the eyes and
skin. Do not attempt to observe the lamp
directly.
9. Refer servicing to qualified personnel.
10. A full cartridge pack may weigh about 20 lbs.
4
SAFETY IFORMATIO

Congratulations on your purchase of a Thermo Scientific
arnstead Nanopure Life Science (UV/UF) ultrapure
water system. This water purification system is designed
to provide nuclease-free (RNase and DNase), DNA-free,
pyrogen-free, low TOC, high resistivity, reagent grade
water that exceeds ASTM Type I, CAP and NCCLS Type I
standards. It uses a four-stage deionization process com-
bined with a UV lamp, an ultrafilter and a 0.2 micron filter
to polish suitable feed water (distilled, deionized, or
reverse osmosis) to produce pyrogen-free (<0.001 Eu/ml),
low TOC (<5.0 ppb) water with a resistivity of up to 18.2
megohm-cm. Water resistivity is continuously monitored
by a resistivity cell and displayed on a digital display.
The Nanopure is designed to automatically clean the
ultrafilter by flushing water through the filter for one
minute every 12 hours. The water is sent to drain.
The electronics can be verified and calibrated utilizing a
N.I.S.T. Traceable Calibration module. See accessory
ordering information.
Please read the instructions carefully to ensure that you
receive maximum benefit from the Nanopure. Also, please
fill out and return the enclosed warranty registration card
as it will help us assure you of proper warranty coverage.
General Usage
Do not use this product for anything other than its intend-
ed usage.
5
Introduction

Dimensions and Clearance Requirements
Dimensions
13.5” W x 19.5” H x 17.0” D (34.3 x 49.5 x 43.2 cm)
Clearances
Sides - 9” (22.9 cm) minimum for servicing.
Above - 3” (7.6 cm) minimum for removal of the top cover.
Front - 4.75” (12.1 cm) minimum for opening the front door.
Feed Water Requirements
Types RO, DI, distilled.
TOC Less than 1.0 ppm.
Turbidity 1.0 N.T.U. maximum.
Pressure Range Gravity feed to 100 psig (7kg/cm2) maximum.
Temperature Range 4°C - 40°C (40-104°F)
TDS (CaCO3) < 70 ppm
Silica < 1 ppm
Silt < 5% SDI
Product Water
Water Quality
Resistivity > 18.0 mΩ-cm
TOC Less than 3.0 ppb
Endotoxin Less than 0.02 Eu/ml
Flow Rate
Up to 1.8 lpm maximum at minimum inlet feed water pressure 10 PSIG with a new final filter.
Volumetric Dispense
Accuracy: ± 5%
Repeatability: ± 3%
Electrical Requirements
The Nanopure is equipped with 2 power cords to be plugged into an electrical outlet of the appropriate volt-
age.
U.K. customers use cord, CRX100 and fuses for 240V installation.
Model D11931 100-240 VAC, 100 watts, 47-63 Hz, 1 phase
6
General Specifications

Environmental Conditions
Operating: 4°C - 40°C; 20% to 80% relative humidity, non-condensing. Installation
Category II (over-voltage) in accordance with IEC 664. Pollution Degree 2 in
accordance with IEC 664.
Altitude limit: 3,500 meters.
Storage: -25°C to 65°C; 10% to 85% relative humidity.
Declaration of Conformity
We hereby declare under our sole responsibility that this product conforms with the technical require-
ments of the following standards:
EMC: EN 61000-3-2 Limits for Harmonic Current Emissions
EN 61000-3-3 Limits for Voltage Fluctuations and Flicker
EN 61326-1 Electrical Equipment for Measurement, Control, and Laboratory Use; Part I:
General Requirements
Safety: EN 61010-1 Safety Requirements for Electrical Equipment for Measurement, Control and
Laboratory Use; Part I: General Requirements
per the provisions of the Electromagnetic Compatibility Directive 89/336/EEC, as amended by 92/31/EEC and
93/68/EEC, and per the provisions of the Low Voltage Directive 73/23/EEC, as amended by 93/68/EEC.
The authorized representative located within the European Community is:
Thermo Fisher Scientific
419 Sutton Road
Southend On Sea
Essex SS2 5PH
United Kingdom
Copies of the Declaration of Conformity are available upon request.
7
GE ERAL SPECIFICATIO S

1. Remove the unit from its shipping container.
Remove all contents carefully. Ensure that the
UV lamp, ultrafilter, feed and drain tubing,
cleaning cartridge, wall bracket, accessory
parts bag and power cords (see list below)
are removed from the packaging materials
before discarding. Put the Nanopure on a
bench.
UV Lamp LMX13
Cleaning Cartridge CMX25
Wall racket (Unit) C1190X12
Wall racket (Remote Display) C1190X10
Ultrafilter FL1192X1
Accessory Parts Bag Includes:
Feed Water Tube, 3/8” O.D. TU1119X7
Drain Tube, 14” O.D. TU1190X12
Display Cable WHX20
lank Display DL1190X18
Plug Adapter CEX42
Power Cords
Also required for installation:
* Customer Supplied Fasteners to mount unit and remote
display.
8
Unpacking

9
Choosing a Site
The Nanopure features a removable control panel display
which allows the system to be mounted almost anywhere
within the laboratory. Use the wall bracket for wall mount-
ed systems as a template to drill mounting holes. (The
Nanopure does not include screws and fasteners for
mounting.) Please refer to the “General Specifications”
section for clearance requirements.
Installation
OTE
The outlet of a gravity feed storage
reservoir must be above or at the
same level as the inlet of the
Nanopure.
********************
************************
Caution
Wall composition, condition and
construction as well as fastener type
must be considered when mounting
this unit. The mounting surface and
fasteners selected must be capable of
supporting a minimum of 150 lbs.(68
kg). Inadequate support and/or fasten-
ers may result in damage to mounting
surface and/or equipment. If you are
unsure of mounting surface
composition, condition and construc-
tion or correct fasteners, consult your
building maintenance group or
contractor.
Warning
Do not locate the Nanopure directly
over equipment that requires electrical
service. Routine maintenance of this
unit may involve water spillage and
subsequent electrical shock hazard if
improperly located.
Do not use in the presence of
flammable materials; fire or explosion
may result. This device contains
components which may ignite such
materials.

Ultrafilter Installation
Remove the ultrafilter from its protective bag. Install the
ultrafilter as follows:
1. Open the front (right side) door and right side
door.
2. Remove restraints (twist tie) from the three
tubes.
3. Locate the metal bracket and separate the
Velcro®strap.
4. Remove the cap on the top side port of the
ultrafilter (make sure the bottom cap on the bot-
tom side port is secure). Insert side ports into
the holes in the metal bracket.
5. Align the ultrafilter with the metal bracket (Side
ports should face the back of the unit) and push
the bottom fitting tightly into the bottom connec-
tor.
6. Push the top fitting of the ultrafilter into the top
connector, making sure the connection is tight.
7. Secure the ultrafilter with the velcro strap.
8. Connect tubing with luer fitting to the top side
port.
9. Close and latch right side door and front (right
side) door.
ISTALLATIO
Figure 2: Ultrafilter Installation
ote
Do not install the ultrafilter until the
Nanopure is ready for use. If the unit
sits for longer than 72 hours without
use, it will become contaminated and
may affect product water quality.
10
Figure 1: Ultrafilter with fittings
ottom side port with cap
Top side port with cap
removed
Metal bracket
Velcro strap
Figure 3: Ultrafilter Connections (Right side view)
ottom connector
Top connector
ote
The ultrafilter must be installed before
the 0.2 micron filter. Please refer to
“0.2 Micron Filter Replacement” under
“Maintenance and Servicing” for
instructions on how to replace the 0.2
micron filter.
Top side port
tubing with
luer fitting
® Velcro is a registered rademark of Velcro Industries B.V.
Flow
Flow

UV Lamp Installation
Locate the UV chamber inside the left door of the
Nanopure. Install the UV Lamp as follows:
1. Disconnect the power cord from the unit.
2. Access the left side of the unit by unlatching the
screw securing the door with a flathead screw-
driver. Open the door. The UV lamp will be
installed vertically.
3. Remove the UV lamp from its packaging. DO
NOT TOUCH THE GLASS PORTION OF THE
LAMP! It is recommended that lint-free gloves be
worn when handling the lamp. The glass portion
must be free of fingerprints, perspiration, etc.
Even a light coating of perspiration will reduce
the effectiveness of the lamp. If the glass portion
of the lamp is touched, clean it with a damp, lint-
free cloth: use isopropyl alcohol as required.
4. Remove black cap by sliding off UV housing.
5. Insert the lamp halfway into the UV lamp cham-
ber and plug it in, then fully insert the lamp into
the chamber.
6. Make sure the UV lamp cable is tucked behind
the chamber before closing and relatching the
door.
Other Accessories
Optional accessories for this unit include a float switch,
low pressure switch, N.I.S.T. Traceable Calibration Module,
standard remote dispenser, Accu DIspense volumetric
remote dispenser, dispense overflow cutoff float and print-
er. If you purchased a float switch or low pressure switch,
refer to page 32 of this manual. If you purchased a stan-
dard or Accu DIspense volumetric remote dispenser, refer
to their respective operator’s manuals for installation
instructions.
11
ISTALLATIO
Caution
DO NOT TOUCH THE GLASS POR-
TION OF THE LAMP! It is recom-
mended that lint-free gloves be worn
when handling the lamp. The glass
portion must be free of fingerprints,
perspiration, etc. Even a light coating
of perspiration will reduce the effec-
tiveness of the lamp. If the glass por-
tion of the lamp is touched, clean it
with a damp, lint-free cloth: use
isopropyl alcohol as required.
ote
The UV lamp contains mercury. If
broken or no longer needed, do not
dispose of the UV lamp in the trash.
Recycle or dispose of the UV lamp as
hazardous waste.
Figure 4: UV Lamp Installation - Left side view

ench Mounting
1. Place the Nanopure a bench top that is accessi-
ble to pretreated water, electricity and an atmos-
pherically vented drain.
Wall Mounting
Install the Nanopure on a wall in a convenient location
that is accessible to water, an atmospherically vented
drain and electricity.
1. Locate the wall bracket packed separately from
the unit.
2. Using the wall bracket as a template, locate and
drill the mounting holes in the wall. A minimum
of four (customer-supplied) fasteners will be
required — two on the top and two on the bot-
tom.
3. Attach the wall bracket to the wall using the cus-
tomer-supplied fasteners.
4. Remove the locking screws on each side of the
wall bracket.
5. Pull the two locking slides on each side of the
wall bracket out as far as they will go.
6. Hang the unit on the wall bracket by sliding the
mounting pins into the wall bracket slots.
7. Push the locking slides on each side of the wall
bracket in as far as they will go.
8. Replace the locking screws.
12
ISTALLATIO
ote
Please refer to the “General
Specifications” section for clearance
requirements.
Warning
Do not locate the Nanopure directly
over equipment that requires electrical
service. Routine maintenance of this
unit may involve water spillage and
subsequent electrical shock hazard if
improperly located.
OTE
The outlet of a gravity feed storage
reservoir must be above or at the
same level as the inlet of the
Nanopure.
********************
************************
Caution
Wall composition, condition and con-
struction, as well as fastener type,
must be considered when mounting
this unit. The mounting surface and
fasteners selected must be capable of
supporting a minimum of 150 lbs.(68
kg). Inadequate support and/or fasten-
ers may result in damage to mounting
surface and/or equipment. If you are
unsure of mounting surface composi-
tion, condition and construction or cor-
rect fasteners, consult your building
maintenance group or contractor.

Installing the Control Panel in a
Remote Location
For your convenience, the control panel can be removed
from the unit and mounted at a convenient location within
10 ft. (3.1 m.) of the unit. To remove the control panel from
the unit:
1. Turn the unit OFF and disconnect it from the
power supply.
2. Slide the control panel upward about 1/4” (.64
cm) to 3/8” (.95 cm) - (just enough to clear con-
nector on top cover), pull forward, and remove.
(The control panel fits tightly in the unit so it may
be difficult to remove.)
3. Replace the control panel with the blank panel
provided with the unit to protect the electrical
connector.
4. Using the wall bracket as a template, locate and
drill the mounting holes in the wall. A minimum
of two (customer-supplied) fasteners will be
required. Attach the wall bracket to the wall
using the customer-supplied fasteners.
5. Locate the 25-pin connector on the back top
right of the unit. Remove the protective black
cover and store it for future use if the control
panel is returned to the top cover.
6. Locate the 10 ft. (3.1 m.) 25 pin M-F cable
included with the unit; attach the female end to
the 25 pin connector on the back top right of the
unit, and the other end to the connector on the
bottom of the control panel.
7. Tighten the cable screws on each end to secure
the cable to the unit and control panel.
8. The control panel may now be mounted on the
wall.
13
ISTALLATIO
ote
The removable control panel was not
designed to be repeatedly removed
from the unit, therefore, you may
experience difficulty when attempting
to remove it. It is therefore
recommended that the control panel
be permanently mounted in a remote
location or remain intact with the unit.
Caution
Repeated removal and replacement of
the control panel from the top cover
may eventually cause it to become
damaged.
ote
The blank protective cover on the rear
side panel display connector should
remain in place when the display is
not remotely located.
lank panel
Wall Mount
racket
Figure 5: Mounting the Control Panel
ote
A bracket is available that will allow
you to mount the control panel on the
bench. If bench mounting is desired,
please order bracket AY1367X2.

Water Connections
Feed Water Connection
1. Locate the length of 3/8” O.D. tubing provided with
the unit with a quick disconnect insert on one end
and a 3/8” (.95 cm) O.D. X 1/4” (.64 cm) NPT tub-
ing adapter on the other.
2. Install the tubing adapter onto your incoming water
line. We recommend a customer supplied shut off
valve be installed in your feed water line. Do not
connect the feed water to your Nanopure. You will
connect the feedwater during the “Initial Cleaning”
procedure explained later in this manual. Note:
The cartridge pack and ultrafilter must be installed
before connecting water line.
3. If a pressure switch is to be used, see the
“Installing a Float or Pressure Switch” section for
more information.
Atmospheric Drain Connection
When the Nanopure flushes its membrane, the water used
is sent to drain through this connection. To install:
1. Locate the drain water tubing. This is the 1/4” (.64
cm) O.D. tubing that is approximately 6 ft. (1.9 m.)
long. The atmospheric drain fitting is located on
the lower left side of the Nanopure.
2. Route the other end of the drain water tubing to an
atmospherically vented drain and make a connec-
tion. Ensure there are no kinks in the tubing and
that it proceeds in a downward plane. Proceed to
“Initial Operation.”
ISTALLATIO
Figure 6: Water Connections - Left side view
Caution
Do not connect feed water until direct-
ed to do so during “Initial Cleaning.”
Pump
Interlock
Remote 1
Remote 2
Feed Water
Inlet
Atmospheric
Drain
14
ote
To prevent leaking, push the tubing into
the atmospheric drain connection until it
bottoms out.
Accu DIspense
control cable
Figure 7: Water Connections - Right side view
Overflow Float
Connection

Tubing Installation
To make tubing connections:
1. Make sure the tubing is cut off reasonably
square and that no plastic burrs or ridges
are present.
2. *Mark from end of tube the length of insertion.
Tube size Insertion length
1/4 O.D. 1.75 cm (11/16”)
3/8 O.D. 1.9 cm (3/4”)
3. Wet the tube end with water and insert tube
straight into fitting until it bottoms out on interior
shoulder and insertion mark is no longer visible.
4. To remove tubing, push collet toward fitting body
and pull on tubing. To reuse fitting, begin assem-
bly at step one.
Electrical Connections
The Nanopure comes with a 120 V power cord with (2)
1.6 amp fuses and 240 V power cords with (2) 0.63 amp
fuses.
The Nanopure is not shipped with fuses installed in the
fuse draw of the power module. efore connecting the
power cord to the power module, install the proper fuses
in the fuse holder. Refer to the figure on the left.
15
ISTALLATIO
Fuse Holder
Power Switch
Power Cord
Figure 10: Electrical Connections
COLLET
TUBING
**
TYPICAL
FITTING
Figure 8: ubing Adapter Installation
Figure 9: ubing removal

16
Main Power Switch
The main power switch on the Nanopure is located on the
lower back right side of the unit (as you face the front of
the unit), directly above the power cord receptacle.
Control Panel
The Nanopure is controlled through a panel which incor-
porates switches to control its functions: START/STOP,
STAND Y, DISPENSE, DOWN, UP, ENTER and ACK.
This control panel utilizes a digital display to show system
information and the purity of the product water. The inten-
sity (brightness) of the display may be adjusted according
to user preference. See “Adjusting Display rightness” in
the “User Settings” section of this manual.
A single LED located on the top of the control panel will
illuminate to inform you of the system status as follows:
• LED is not illuminated: System is OFF or in (Idle)
mode.
• Solid Green LED: System is recirculating and
operating normally.
• linking Green LED: System is in Standby mode.
• Red LED: System is alerting user to an
operational error or maintenance issue.
The control panel can be removed from the unit and
remotely mounted. Please refer to “Installing the Control
Panel in a Remote Location” in the “Installation” section of
this manual for more information about how to remove the
control panel from the unit.
Controls
Figure 11: Nanopure Life Science (UV/UF)
Control Panel
ote
The removable control panel was not
designed to be repeatedly removed
from the unit, therefore, you may expe-
rience difficulty when attempting to
remove it. It is therefore recommended
that the control panel be permanently
mounted in a remote location or
remain intact with the unit.
LED

17
Switches
When the main power switch (on the lower back right side
of the unit as you face the unit) is ON, the switches on the
control panel function as follows:
START/STOP allows you to alternate the unit between the
normal (recirculation) mode; when the display is showing
purity, and the (Idle) mode.
STA DBY allows you to put the unit into standby, recircu-
lating water for 10 minutes/hour. The display will read
“Standby” during periods of inactivity and “Recirculating”
and the time remaining during the 10 minute recirculation.
DISPE SE allows you automatically deliver water from
the unit. Please refer to”Automatic Dispensing” in the
“User Settings” section of this manual for information.
UP and DOW arrows allow you to scroll between menu
options/items and values.
BACK allows you to return to the previous menu
option/item. Please note that use of the ACK switch from
a selection screen will return you to the previous menu
option/item while maintaining the selection’s value upon
entry.
E TER allows you to activate a selected menu
option/item and also functions as “Yes” whenever an
option with a question mark appears.
DISPE SE K OB when the unit is in the recirculation
mode, push to the right to deliver water continuously until
pushed back to the middle. Push to the left to deliver
water manually until button is released.
CO TROLS
ote
The unit MUST be in the normal recir-
culating mode (when the display is
showing purity) in order to dispense
water.

18
Cartridge packs will come bagged with four manifold
connection caps.
Part Application
DIamond Kit Organic Free R/O & Distilled Feed
D50280 Ultra-Low Organics, Type 1 Water,
Reverse Osmosis or Distilled
Water Feed
DIamond Kit Organic Free Deionized Feed
D50281 Ultra-Low Organics, Type 1 Water,
Deionized Water Feed
DIamond Kit Type 1 R/O & Distilled Feed
D50282 Low Organics, Type 1 Water,
Reverse Osmosis or Distilled
Water Feed
DIamond Kit Type 1 Deionized Feed
D50283 Low Organics, Type 1 Water, DI
DI Water Feed
Each cartridge pack includes one 0.2 micron absolute
final filter.
Cartridge Pack Installation
1. Open front (left side) door. Turn the cartridge
pack so the caps are facing you. Remove the
caps.
2. Verify that each of the four posts on the car-
tridge pack has an o-ring.
3. Lift unit manifold upwards, insert cartridge pack
and align the pack so that it mates with the unit
manifold.
4. Lower unit manifold until it is flush with the top of
the cartridge pack.
5. Hand tighten wing head screws securely.
6. Close door.
Initial Operation
ote
Do not install the 0.2 micron filter and
bell assembly at this time.
Caution
Do not allow the Nanopure to operate
unless water is available to the unit.
Warning
Depressurize system prior to removing
cartridge pack.
Manifold
Figure 12: Cartridge Pack Installation

19
Initial Rinse
1. Attach the feed water line to the unit by snap-
ping the quick disconnect coupling into the quick
disconnect body in the lower left back of the
unit.
2. Attach an atmospheric drain line [1/4” (.64 cm) ]
tubing by pushing into the quick connect fitting
on the lower left back of unit. See layout connec-
tion under the “Water Connections” section.
3. Check to ensure the dispense knob is in the
OFF (middle) position.
4. Select the appropriate power cord, remove and
install the two fuses into the fuse draw in the
power entry module. U.K. customers use cord
CRX100 and fuses for 240V installation.
5. Connect/attach to proper electrical outlet and
the unit.
6. Turn the unit on by turning the main
power switch to the “I” (ON) position.
7. The system greeting will display the type of unit
you own. This greeting is “UV/UF.”
8. The system electronics will initialize and check
its calibration. (All units have been factory cali-
brated.) If calibration is OK the display will show
“Calibration (passed).” The display will next read
“Self Test (in progress) Self Test. Passed.”
Finally, the display will read “10 (±0.2) MΩ-cm.”
This is a reading of the calibration reference
value.
9. From the (Idle) mode, when the display reads,
“Nanopure (Idle) xx:xx:xx xx/xx/xx,” press
ENTER to run an air purge.
10. Unit will display, “Air Purge?” Press ENTER.
11. Upon completion of the air purge, complete the
“System Cleaning Procedure.”
IITIAL OPERATIO
Warning
Use a properly grounded electrical
outlet of correct voltage and current
handling capacity.
Caution
Never dispense water without first
installing hose barb provided in
parts bag or final filter supplied with
cartridge pack.

20
System Cleaning Procedure
Your Nanopure has been shipped with a cleaning syringe
(Cat. No. CMX25). When the system is new or whenever a
new cartridge pack is installed, the system should be
cleaned. For UV/UF units, it is best to perform cleaning
procedures when the system or water is not required. The
entire cleaning procedure will take approximately 3.5
hours to complete. Clean your Nanopure as follows:
1. (If you have installed an Accu DIspense volu-
metric remote dispenser, place it in manual
mode.) From the (Idle) display, press the UP or
DOWN arrow until display reads, “Clean Unit?”
2. Press ENTER.
3. Unit display will ask if you have “Disconnected
Inlet Water (NO).”
4. Disconnect feed water supply at the quick-dis-
connect inlet valve on left side of unit.
5. Press the UP or DOWN ARROW to select (YES)
and then press ENTER. Display will now read,
“Injected Cleaner (NO).”
6. Open front (left side door) to expose cartridge
pack. Remove solution syringe from wrapper.
7. Remove luer cap on system injection port,
located on the right side of the cartridge pack
manifold by turning counterclockwise.
8. Remove syringe luer cap and attach syringe to
the system luer fitting.
9. Slowly inject solution into system and remove
syringe. Avoid injecting air into the system.
10. Replace luer cap on injection port and close
door.
11. Press the UP or DOWN arrow to select (YES)
and then press ENTER. Display will now read,
“Reconnected Water (NO).”
12. Attach feed water supply removed in step 4.
IITIAL OPERATIO
Warning
Avoid splashing cleaning solution on
clothing or skin.
Ensure all piping connections are tight
to avoid leakage.
Ensure adequate ventilation.
Carefully follow manufacturer’s safety
instructions and material safety data
sheets.
This device to be used with water
feeds only.
Cleaning agents must be used in com-
pliance with instructions in this manu-
al. Failure to comply with the above
could result in explosion and personal
injury.
ote
After cleaning is complete, the clean-
ing timer will need to be reset (refer to
Resetting the Cleaning Timer) for
another six month timing sequence.
Injection Port
Figure 13: Injecting Cleaning Solution