VWR Avantor 171-1249 User manual

Version 3 Issue 08/2021
VWR®A Water System
INSTRUCTION MANUAL
European Catalogue Numbers:
171-1249 VWR A Water System
171-1250 VWR A Water System with TOC

2vwr.com I Instruction manual VWR® A Water System
Legal Address of Manufacturer
Europe
VWR International bv
Researchpark Haasrode 2020
Geldenaaksebaan 464
B-3001 Leuven
+ 32 16 385011
be.vwr.com
UK Importer:
VWR International Ltd
Hunter Boulevard, Magna Park
Lutterworth, Leicestershire, LE17 4XN
uk.vwr.com
Country of origin China

3vwr.com I Instruction manual VWR® A Water System
Table of Contents
1 INTRODUCTION
1.1 System Exterior
1.2 Product Features
1.3 Main Applications
1.4 Specifications
1.5 Operation Principles
1.6 Technical Specifications
2 INSTALLATION
2.1 Installation Site Requirements
2.2 Feed Water Requirements
2.3 Feed Water Quality Measurements
2.4 Installation
3 SYSTEM STARTUP AND OPERATION
3.1 Check List Prior to System Startup
3.2 System Initial Startup
3.3 System Setting-up
3.4 Information Menu
3.5 Maintenance Menu
4 DISPENSING WATER
4.1 Dispensing RO Water
4.2 Dispensing UP Water
4.3 Adjusting Dispense Rate
4.4 Volumetric Dispensing
5 MAINTENANCE
5.1 Basic Alerts
5.2 Basic Alarms
5.3 System Cleaning
5.4 Replacing Consumables
5.5 History Inquiry and Export
6 PARTS AND ORDER INFORMATION
7 TECHNICAL SERVICE
8 WARRANTY
9 DISPOSAL

4vwr.com I Instruction manual VWR® A Water System
1 INTRODUCTION
The VWR A water system is designed to produce ultrapure water (Type I) and RO water directly
from tap water. Water quality produced meets or exceeds the corresponding ASTM, CAP, CLSI
and ISO 3696 / BS 3997 water standards.
This manual describes in detail about system performance characteristics, installation, operation,
and routine maintenance. Please read this manual thoroughly for its instructions on installation,
use and maintenance. Proper installation, use and maintenance guarantee the continuous flow
of high quality ultrapure water.
Please contact us or your local distributor if you encounter any issues during installation and use.
Professional engineers are fully trained to support you.
Safety Information
WARNING!
1) Always power down the system before plug or unplug any hardware. Never hot swap
(hot plug) any hardware, including dispenser, monitor as it may damage control
boards.
2) Disconnect the unit from the power supply prior to perform service work.
3) Refer service to qualified personnel.

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1.1 System Exterior
1
Crossbar and dispenser rest
(with optional accessories)
2
Side panel handle
3
Side panel
4
Electrical connections
5
Water outlets
6
Wall mount ports
7
Outlets for cable or power adapter
8
USB Port
9
SD card slot
Description of the system
The VWR A manages the production and distribution of ultrapure water and RO water from tap
water. It consists of three main units:
◆Main System: manages the production of ultrapure water and RO water.
◆Dispenser: integrates the touchscreen and manages the dispensing.
◆Control Console: controls and monitors the water system and other components on the 8-inch
touchscreen.
2
1
3
4
5
Main System
Control Console
7
8
6
6
9

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1.2 Product Features
The VWR A ultrapure water system provides an integrated solution for lab water supply. This
system is easy to install, easy to operate and easy to maintain.
This system has the following features:
◆Type I ultrapure water and RO pure water are produced directly from tap water.
◆The system can be link to multiple dispensers via cable or wireless.
◆Internal P Pack cartridge removes oxidants, organics, particles and scaling ions to prevent
them from fouling the RO membranes.
◆The RO drain water is reused to increase the water yield. It is more environmentally friendly.
◆Internal RO membrane removes over 99% of large molecules and particles and 95% of ions
in water.
◆Ultra purification cartridge is filled with media to remove trace ions and organics.
◆Built-in 185/254 nm dual wavelength lamp reduces TOC level in ultrapure water.
◆Various final filters (optional) can ensure ultrapure water without particles, bacteria or
pyrogen.
◆RFID tags ensure perfect placement of consumables and trace their performance.
◆The control console is an 8 inch touchscreen. The console controls system and peripheral
devices (Such as dispensers). All operations can be done on the console.
◆Water quality, operation parameters, the status of the system, dispensers, components, and
peripheral devices are stored and displayed on the large colorful touchscreen monitor.
◆The console screen and dispenser screens are water-proof. You may operate the console
and dispenser with wet latex gloves on.
◆Signature verification is required for maintenance and service.
◆VWR provides full documents support to meet user’s GMP, GSP, GAP, GCP, GLP
requirements.

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1.3 Main Applications
Pure water and ultrapure water can be used in many areas. Here are some typical
applications.
Ultrapure Water
RO Water
Important and critical applications
Routine and non-critical applications
•HPLC (High Performance Liquid
Chromatography) mobile phase
preparation
•Preparation of reagent blank solution
•As sample diluents for GC, HPLC,
AA, ICP-MS and other analytical
techniques
•Preparation of buffer and culture
media for mammalian cell culture
•Nano-material science
•Preparation of molecular biology
reagents, etc.
•Glassware cleaning
•Washing machine for glassware
•Water bath water
•Autoclave
•Feed water for laboratory animals
•Other routine use

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1.4 Specifications
RO Water
Water Production Rate
32 L/h at 25 ℃
Dispensing Rate
Variable speed dispensing up to 0.6 L/min
Conductivity
Typically < 20 μS/cm (at 25 ℃)
Rejection Rate
> 95%
Ultrapure Water (Type I)
Dispensing Rate
Variable speed dispensing up to 0.6 L/min
Resistivity
18.2 MΩ.cm (at 25 ℃)
TOC
< 5 ppb
Particles (>0.2 μm)
No particles (with a 0.2 μm final filter or Bio-filter)
Microorganism
< 0.01 cfu/mL (with a 0.2 μm final filter or Bio-filter)
Pyrogen Content
< 0.001 EU/mL (with Bio-filter)
RNAses
< 0.5 pg/mL (with Bio-filter)
DNAses
< 10 pg/mL (with Bio-filter)
Electrical Connections and Specifications
Operating Voltage
24 VDC
Input Voltage
100 – 240 VAC
Main System Power
< 200 W
Dimensions and Weights
Main System
Width × depth x height
32 × 44 × 54 cm (12.6 × 17.3 × 21.3 in)
System Weight
20 kg
Control Console
Length x width
22 × 17 cm (8.7 × 6.7 in)
Control Console Weight
0.75 kg
Dispenser
Width × depth x height
21× 29 × 61 cm (8.3 × 11.4 × 24.0 in)
Dispenser Weight
5 kg

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1.5 Operation Principles
VWR A water system produces ultrapure water and pure water directly from tap water. Most
particles, ions and organic compounds are removed through the pre-filtration, RO membrane.
When in need of ultrapure (UP) water, RO water goes through a UV lamp chamber with a dual
wavelength UV lamp to destroy trace organic pollutants in water, then through a polishing cartridge
to remove the last trace of ions, then a 0.2 μm final filter to the outlet.
VWR A Water Flow Diagram
No.
Description
No.
Description
C1
RO Booster Pump
C2
Distribution Pump
I1
Feed Conductivity Sensor
I2
RO Conductivity Sensor
I4
TOC Sensor (optional)
I5
UP Resistivity Sensor
N2
185 nm UV Lamp
O2
P Pack
O3
U Pack
O6
RO Packs
P
Pressure Sensor
S1
Inlet Filter
S2
Inline Filter
V
Flow Meter
S1
S2
I1
I2
I4
I5
O2
O6
O3
C1
C2
V
HP Dispenser
UP Dispenser
N2
Tap water

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1.6 Technical Specifications
Measurement Range
Channel A (Feed Water): 1 – 1999 μS/cm
Channel B (RO): 1 – 199 μS/cm
Channel C (UP): 1 –18.2 MΩ·cm
Channel D (HP): 1 –18.2 MΩ·cm
Pressure Range
0 – 1.6 MPa
Flow Meter Range
1 – 30 L/min
Temperature Range
0 – 100 ℃
Temperature Compensation
Range
Automatic temperature compensation of readings
Temperature compensation range: 5 – 45 ℃ to 25 ℃

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2 INSTALLATION
2.1 Installation Site Requirements
Item
Requirements
Installation space
≥90 cm×50 cm total
Feed water
Municipal water, outlet diameter > DN 20, ball
valve，NPT thread
Drain water tubing
> DN 50
Working Temperature
5 –45 oC
Power
100 –240 VAC ± 10%，1 KW (5 A)
Humidity
20 –80%
2.2 Feed Water Requirements
Parameter
Value or Range
Pressure
15 –90 psi (1.0 - 6.0 bar)
If the pressure is above 6.0 bar, needs to install
an external pressure regulator.
Conductivity at 25 °C
< 1000 μS/cm
pH
4 –10
Water temperature
5 –45 ℃
Total dissolved solids (TDS)
< 500 ppm
Total Organic Carbon (TOC)
< 2000 ppb
Hardness (as CaCO3)
< 120 mg/L (< 120 ppm): use 171-1255
120 –180 ppm: use 171-1256
> 180 ppm: softener recommended
Free or total chlorine
< 1.5 ppm
2.3 Feed Water Quality Measurements
Parameter
Test Method
Pressure
Use a pressure gauge
Conductivity at 25 °C
Use a conductivity meter
pH
Use a pH test strip
Hardness and chlorine
Use a reputable brand test strip
Total dissolved solids (TDS)
Use a TDS meter
Total Organic Carbon (TOC)
Use a TOC analyzer

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2.4 Installation
2.4.1 Items Included
Package
No.
Name
Quantity
Note
1
VWR A Main System
1
2
Control Console
1
Including a cable connected to main
system
3
Accessories Bag
1
Including 8 mm PE tubing (8 meter), one
roll of Teflon tape, a male connector, and a
power adapter (with power cords)
4
Instruction Manual
1
On USB
5
Quick Installation Guide
1
2.4.2 System Structure and Flow Diagrams
2.4.2.1 Main System Back Side View
Illustration of water inlets and outlets
No.
Label
Description
Tubing Diameter
Connect to
A
HP Dispenser A
For pure water
8 mm
Dispenser
B
HP Dispenser B
For pure water
8 mm
Dispenser
C
EDI Drain
Spare
8 mm
D
Pure Water In
Spare
8 mm
E
Product To Tank
RO product outlet
8 mm
F
UP Dispenser A
For ultrapure water
8 mm
Dispenser
G
UP Dispenser B
For ultrapure water
8 mm
Dispenser
H
RO Drain
RO drain outlet
8 mm
Drain
I
Tap Water In
Tap water inlet
8 mm
Tap water
J
Spare
Spare
8 mm
A
I
H
G
F
E
D
C
B
J

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Description of electrical control board
No.
Label
Description
Connect to
1
Feed Valve
For the feed solenoid valve control
line
Feed valve (optional)
2
Tank UV
For the sanitization module control
line
Not in use
3
Feed Pump
For the booster pump control line
Feed pump (optional)
4
Power
Power cord port
Power adapter
5
Prefilter Sensor
For backwash signal line
Prefilter (optional)
6
Overflow Sensor
For overflow sensor signal line
Not in use
7
Leak Sensor
For leak sensor signal line
Leak sensor (optional)
8
Level Sensor
For the pure water tank level
sensor control line
Not in use
9
CAN A
Data cable port
Dispenser or control console
10
CAN B
Data cable port
Dispenser or control console
1
9
8
7
6
5
4
3
2
10

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2.4.2.2 VWR A External Connection Diagram
Red Line: Electrical loop
Blue Line: Water loop
Power supply
HP dispenser
Tap water
Feed valve
RO Drain
Leak detector
UP dispenser
Dispenser
adapter

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2.4.3 Installing the Leak Protector
2.4.3.1 Leak Protector Specifications
Catalog No.
171-1476
Operating voltage
24V DC
Cable length
3 M to solenoid valve
Fitting
1/2 ″female BSP (Inlet)-8 mm quick
connector (Outlet)
Method of water leak detection
Conductivity. Put the sensor near the
water system
Operating temperature
5 –45 ℃
Maximum inlet pressure
6 bar (90 psi)
2.4.3.2 Illustration of Installation
Outlet
Inlet
Feed valve
Leak
sensor
Terminals

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2.4.3.3 Installation
Follow the steps below if the diameter of the faucet is 1/2 inch male thread.
a) As the picture shown above, connect the inlet of the feed valve to the faucet.
b) Cut an appropriate length of 8 mm PE tubing. Insert one end of the tubing into the port
Tap Water In on the main system and the other end into the outlet of the feed valve.
c) Place the sensor metal probes side down at a lower point on the floor or near the water
system.
d) Plug the terminal of feed valve into the port Feed Valve on the back of the main system,
and plug the terminal of leak sensor into the port Leak Sensor.
Follow the steps below if your system is equipped with a prefiltration device.
a) As the picture shown above, connect the inlet of feed valve to the faucet.
b) Cut an appropriate length of 8 mm PE tubing. Insert one end of the tubing into the inlet of
prefiltration device and the other end into the outlet of the feed valve.
c) Similarly, cut another appropriate length of 8 mm PE tubing. Insert one end of the tubing
into the port Tap Water In of the main system and the other end into the outlet of the
prefiltration device.
d) Place the sensor metal probes side down on the floor or near the water system.
e) Plug the terminal of feed valve into the port Feed Valve on the back of the main system,
and plug the terminal of leak sensor into the port Leak Sensor.
2.4.3.4 Instruction for use
The leak protector is activated automatically when the system powers up.
When it detects water, the system will shut the Feed Valve down, and switch to Standby mode
automatically. A red icon will appear on the screen and an alarm message box will pop
up. The message “Leak or Tank Overflow, all valves are closed, system could run after
troubleshooting” will disappear by tapping Confirm when the leak is resolved. Switch
system from Standby to Ready mode manually so system will work again.
Outlet
Connect to Feed
Valve port

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2.4.4 Installing the Dispensers
This water system offers two different dispensers: Dispenser 1 has an anchor base and stand,
while Dispenser 3 is anchored on the system itself with no dispenser base.
2.4.4.1 Items included for Dispenser 3
No.
Description
Connect to
1
Touch screen
2
Dispense button
3
Dispenser tubing connector
Main system
4
Dispenser cable connector
Main system
Package
No.
Name
Quantity
Note
1
Dispenser
1
2
Base kit
1
Including screws
3
Accessories bag
1
One dispenser adapter, two 8 mm tee
connectors, two 8 mm quick connectors,
eight 8 mm lock-clamps, two 6 mm lock-
clamps, 1.5 m CAN cable

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2.4.4.2 Installing the Dispenser 3 (171-1275)
a) Take out the base kit and assemble. The base is assembled differently on the left and right sides
of the crossbar. Refer to the pictures below to install the base.
b) Open the side panels of the main system on both sides. Remove the screws as shown below.
c) Remove the corresponding cap from the crossbar. Remove the insert block from the cap.
d) Insert the inner block into the base and then insert the base into the crossbar. Fix it with the
screw.
Install one base on the
left side of the system
Install the other base on
the right side of the system
Base kit
The left side of the system
The right side of the system
Caps
Fixed block

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UP Dispenser A
HP Dispenser A
CAN A
UP Dispenser B
HP Dispenser B
e) Install the tubing and cable.
Ultrapure dispenser: Insert the dispenser tubing connectors into the UP Dispenser A port
and UP Dispenser B port on the back of the main system respectively. Then insert the
dispenser cable connector into the CAN A or CAN B port on the back of the system.
Pure dispenser: Insert the dispenser tubing connectors into the HP Dispenser A port and HP
Dispenser B port on the back of the VWR main system respectively. Then insert the
dispenser cable connector into the CAN A or CAN B port on the back of the system.
Pure and Ultrapure dispenser: Follow the picture below to connect the pure dispenser and
the ultrapure dispenser using the dispenser adapter.
Fixed block
Base
Dispenser adapter
HP dispenser
UP dispenser
UP Dispenser A
UP Dispenser B
CAN A

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2.4.4.3 Installing the Dispenser 1 (optional)
`
No.
Description
Connect to
A
8 mm tubing port
Main system
B
8 mm tubing port
Main system
C
Data cable port
Main system or power
D
Data cable port
Main system or power
E
Foot switch port
Foot switch (Optional)
2.4.4.3.1 Items included
Package
No.
Name
Quantity
Note
1
Dispenser base
1
The handle is connected to the base with
corrugated pipe.
2
Center post
1
With Screw
3
Crossbar
1
4
Accessories bag
1
Including one roll of PVC tubing, a male
barb connector and an Allen wrench.
2.4.4.3.2 Installing the Dispenser Kit (171-1273)
a) Open the package and take out the dispenser from the package. Set the dispenser base on a
stable surface. This kit comes with a 3-meter link bundle.
b) Install the dispenser center post to the base, then insert the crossbar on the center post, place
the dispenser handle on the magnetic base of the dispenser arm.
A
B
C
D
E
Crossbar
Center post
Handle