ZINEXTS MagPurix 12A User manual

Zinexts Life Science
Automated Nucleic Acid Purification System
MagPurix 12A
Catalog No.: ZP01005
Rev. Date: Sep 7, 2022
Manual No. IFU-MP01-01005
Version: 2.1
Instruction Manual
Obelis s.a.
Bd Général Wahis 53
1030 Brussels Belgium
Tel: +(32) 2 732-59-54
Fax: +(32)2 732-60-03
[e-mail]

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TABLE OF CONTENTS
Page#
INTRODUCTION ...................................................................................................................................3
SAFFETY INFORMATION ..................................................................................................................4
1.0 Installation................................................................................................................................9
1.1. Composition of the MagPurix 12A system..................................................................9
1.2 Contents of Reagent Kits .....................................................................................................10
1.3 Operating Environment / Condition...................................................................................11
1.4 Unpack the MagPurix 12A system.....................................................................................13
1.5 Overall View .............................................................................................................................16
2.0 Getting Started......................................................................................................................18
2.1Turning on the power .............................................................................................................19
2.2 Preparation...............................................................................................................................19
2.3 Extraction .................................................................................................................................20
2.4 After Extraction Operation ...................................................................................................28
3.0 Cleaning &Maintaining the MagPurix 12A system ......................................................29
4.0 Troubleshooting ...................................................................................................................30
5.0 Specifications........................................................................................................................32
6.0 Warranty..................................................................................................................................32
APPENDIX ...........................................................................................................................................33

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INTRODUCTION
Thank you for purchase of the MagPurix 12A which is a fully automated,
standalone robot that can purify nucleic acids the fast is within 40-55
minutes. With advanced magnetic bead separation technology, it enables you
to have high quality extraction results. Moreover, the most user-friendly
interface makes users free from troublesome parameter settings and
maintenance.
This guide contains important information regarding the safe use of the
MagPurix 12A. Please read this manual carefully before you start to run the
system at the first time, especially for Safety Information.
If there is any question about how to install or operate it, please contact our
certified distributors / agents or email to our technical support center
( [e-mail] ).
Manufacturer Info:
Manufacturer: Zinexts Life Science Corp
Address: 16F., No. 93, Sec. 1, Xintai 5th Rd., Xizhi Dist.,
New Taipei City 221416 , Taiwan (R.O.C)
Tel: [phone]
Fax: [phone]
Mail: [e-mail]
Product of Origin: Taiwan

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MagPurix Magnetic Bead Purification Process
SAFFETY INFORMATION
The meanings of safety precaution marks are as follows:
WARNING:
“WARNING” indicates a dangerous condition that may lead to death or
serious injury.
BIOHAZARD:
This symbol is used to indicate that certain precautions must be taken
when working with potentially infectious material.
CAUTION:
This symbol is used to indicate that non-compliance with instructions or
procedures may lead to physical injury or even death or could cause
damage to the instrument.
Important:
“Important” shows the important notes for usage, as well as prohibited
actions.
Note:
“Note” indicates the notes, procedures that should be obeyed and
supplementary information for use.
HOT SURFACE:

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This symbol is used to label potentially hot instrument surfaces.
IVD
This symbol is In vitro diagnostic medical device.
For your safety and that of others, follow the guidelines provided in the
following pages concerning the use of the MagPurix 12A system.

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About Instrument
WARNING:
Ignoring the following notations may lead to fire or electric shock.
- In countries other than Taiwan, US and Canada, use a power cable
that meets your country’s standard, or contact your local distributor.
- Do not use the MagPurix 12A system with voltage other than the
voltage specified on the device.
- Do not use the MagPurix 12A system with a damaged power plug or a
loose socket.
- If there is dust on the prongs of the power plug or on the plug socket,
remove it with a dry cloth.
- When you disconnect the plug from the outlet, be sure to hold the
power plug itself. Do not pull the power cable.
- For maintenance, disconnect the power plug from the outlet.
- Do not touch the power plug when you hear the crash of thunder.
Do not pour any liquid on the MagPurix 12A system.
Do not place any objects containing liquid on the MagPurix 12A
system. Doing so may cause a device failure, fire, or electric shock.
In the event the device overheats, starts to smoke or smells strange,
immediately unplug the power cable.
CAUTION:
Never attempt to remodel the MagPurix 12A system without the
manufacturer’s permission. Doing so may cause fire or electric shock.
Do not place or drop objects on the MagPurix 12A system. Also refrain
from bumping or knocking it, as doing so may cause a failure or
malfunction of the MagPurix 12A system.
If any liquid materials are left inside the device, wipe it up a soft paper

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tissue, etc. Otherwise, the MagPurix 12A system may be damaged.
Repairs to the MagPurix 12A system should only be performed by
such agencies as are specifically authorized by the ZINEXTS LIFE
SCIENCE CORPORATION.
Only original the ZINEXTS LIFE SCIENCE CORPORATION replacement
parts should be used.
If the equipment is used in a manner not specified by the
manufacturer, the protection provided by the equipment may be
impaired.
About Reagent Kits
CAUTION:
When handling any of the kits, refer to the respective handbook.
Reagents in each kit should be handled by observing the safety
information and precautions regarding the kit.
Extraction should be performed in an appropriate laboratory or
workplace.
Note:
The kits are not supplied with the MagPurix 12A system. Select the desired
kit(s) and order it (them) separately.

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About Samples
BIOHAZARD:
Always wear appropriate gloves, a mask, and safety goggles etc. when
handling any infectious samples.
About Infectious Wastes
When handling or disposing of infectious materials, follow the
laboratory guideline or the law regarding infectious waste to perform
proper incineration, fusion, sterilization, and/or disinfection.
When you use a third party to dispose of it, outsource this work an
operator licensed to handle medical waste subject to special control,
and give them the manifest of the medical waste at the same time.
Zinexts Service Center
For technical problem and instrument maintenance please contact our
service center:
Zinexts Life Science Corp.
www.zinexts.com
16F., No. 93, Sec. 1, Xintai 5th Rd., Xizhi Dist.,
New Taipei City 221416 , Taiwan
Tel: [phone]
Fax: [phone]

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1.0 Installation
1.1.Composition of the MagPurix 12A system
Check that the following are included in the package. Contact your
local representative if you notice any missing part(s).
A
B
C
D
E
Q’ty
A. MagPurix Instrument 1
B. Power Cord 1
C. Sample Tu b e Rack 2
D. Barcode Reader 1
E. User’s Manual 1

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Please make all the components are free from damages as soon as
you get the system. If any damage found, please contact your local
representative for the instant support.
Note:
Zinexts’s global warranty does not cover the damages from the
transportation or improper operation.
1.2 Contents of Reagent Kits
A
B
A. Reagent Cartridge(s)
B. Reaction Chamber(s)
C. Tip Holder
D. Piercing
E. Filtered tip
F. Sample tube
G. Elute tube
D
C
E
F
G

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Note:
-Reagent kits are separated purchase. Please contact your local
agents or representatives to get further info.
-The contents of reagent kits will be various. Refer to the
handbook of kits enclosed in reagent box for details.
1.3 Operating Environment / Condition
Use the MagPurix 12A system in a location that meets the following
conditions:
The space for the allocation of the MagPurix 12A system must be
remained 5-10 cm from instrument to side walls.
A location where power can be provided.
A location where the temperature is 15 to 40°C, and humidity is
30 to 80%RH. (non-condensing)
A location that is flat and stable, with no vibration.
A location away from direct sunlight. (Block the sunlight by
closing curtains or blinds as necessary)
A location which is well-ventilated and not dusty.
A location where the temperature does not go up and down
suddenly. (Warming a cold room suddenly or moving the
MagPurix 12A system from a room with low temperature to a
warm room may cause condensation inside the device, resulting

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in abnormal extraction)
A location where the temperature and humidity are kept within
the specified range (far from water taps, water heaters,
humidifiers, air-conditioners and heaters)
A location far from objects which generate strong magnetic
fields. (motors, transformers, TV, audio speakers, magnets, etc.)
(Bringing the MagPurix 12A system close to any type of magnetic
field may cause a malfunction)
Warning:
Do not use the MagPurix 12A system to a location where it is wet or
can be splashed with water. It may cause a device failure, fire, or electric
shock.
When relocating the MagPurix 12A system, disconnect the plug from
the outlet first. If the power cable is damaged, this may cause a device
failure, fire, injury, or electric shock.
Caution:
Do not use the MagPurix 12A system in an unstable place such as a
slanted surface or a place subject to vibrations. It may cause injury or
device failure.
Do not use the MagPurix 12A system in direct sunlight or close to a
heating device. It may shorten the life of the MagPurix 12A system, or
cause a trouble.
Do not open the maintenance door while performing experiment.
Do not open the drawer while performing experiment.

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Operating Conditions
Items
Conditions
Temperature (°C)
During operation
15 – 40
During down time
0 – 55
Humidity (RH)
During operation
30 – 80
During down time
10 – 80
Max. wet bulb temperature
(°C)
During operation
29 (non-condensing)
During down time
29 (non-condensing)
Temperature gradient (°C/hr)
12 or less (non-condensing)
Humidity gradient (RH/day)
30 or less (non-condensing)
Altitude, operating (m)
1600 or less
1.4 Unpack the MagPurix 12A system
(1) Open the packing box and take out the instrument and related
accessories.
Important:
The MagPurix 12A system has a weight of more than 60 kgs. It
should be lift and moved by two persons.
Hold the moving handler of the instrument from two sides to move
it out from the box.

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Do not hold the outer covering.
Do not hold the front panel.
Do not hold the door.
Caution:
Improper handling of the movement of the MagPurix 12A system
will lead to instrument damages.
For correct and safe use of the MagPurix 12A, install it in a
location that is close to electrical outlet and has enough space for
installation and operation of the mains switch.
Important:
Keep the shipping box and stuffing materials. They will be
needed again when transporting the MagPurix 12A system.
(2) Connect Barcode Reader with the Instrument.
(3) Before turn on the power please makes sure screw-out the screw
which uses to lock the X axis in the RIGHT inside of b a r.
Tool:(4MM hex tool)

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Direction: Counterclockwise at least 3 turns
(4) How to remove the fixing stuff inside the instrument following the
steps below,
i. Plug in the power cord to the instrument and connect to
electric outlet
ii. Turn the power switch on.
iii. Press “STA RT ” button. The piston module will going up, and
you can release the fixing stuff.

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1.5 Overall View
Front view with Door closed
Front view with Door opened
LCM Screen
Door
Moving Handler
Operational Area
UV Lamp
Control Pad
Drawer

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Turn on and off
UV Light
LCM Panel and Control Pad
-LCM displays information of operation instruction guide
and program process status.
-Control pad is used for selection of functions and input of
program and test codes.
LCM
Control Pad
Number
buttons
Pause or
terminate the
program
Start the
program / wake
up from idle
mode
Confirmation
/ Next Step
Cancel
/ Previous Step

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Back View
2.0 Getting Started
Biohazard:
Always wear appropriate gloves, a mask, and safety goggles during any
biohazardous operations in extraction process. Even when touching the
device after any operation with a biohazard risk, wear appropriate
gloves and a mask since the device may be contaminated.
Important:
Before starting extraction, put on appropriate gloves, a mask, and
safety goggles if required by the operation. In the operation from
preparing samples to extraction completion, be careful not to
contaminate the samples with sweat, saliva, etc.
Power Inlet
Power Switch 1 x Barcode Reader 1 x USB Port

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2.1Turning on the power
(1) Make sure that the power cable are connected securely to the
MagPurix 12A system.
(2) Connect the plug of the power cable to the outlet.
2.2 Preparation
The following preparations are required for extraction operation.
Items to be prepared
- Gloves
- Mask
- Safety Goggles
- Reagent Cartridge*
- Reaction Chamber*
- Tip Holder*
- Small tip (Option)*
- Filtered tip*
- Sample tube*
- Elute tube*
- Piercing Pin
For the preparation of samples, refer to the handbook of each
kit.
*: Provided with the Reagent Kits.

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2.3 Extraction
(1) Turn the power switch on and waiting for the LCM screen turn on
and shows “MagPurix 12 System Stand-By”.
(2) Press the “Start” button
(The system will process self-testing, and then go to steady mode)
Note:
The system will block main functions before the completion of self-
testing process.
(3) Open the drawer and remove the sample rack from the
instrument.
1. Load Reagent Cartridges, and all plastics disposables (Reaction
Chamber, Tip Holder, Piercing Pin, Filtered Tip and Sample Tube and
Elute Tube.
(Optionally supplied with some kit types)
Insert the cartridges