Roche Diabetes Care, Inc.
9115 Hague Road
Indianapolis, IN 46256
www.accu-chek.com
ACCU-CHEK, ACCU-CHEK GUIDE, SOFTCLIX, and MYSUGR 
are trademarks of Roche. 
APPLE, APPLE logo, and APP STORE are trademarks of Apple Inc.
GOOGLE PLAY is a trademark of Google Inc.
The Bluetooth®word mark and logos are registered trademarks 
owned by Bluetooth SIG, Inc. and any use of such marks by 
Roche is under license.
© 2021 Roche Diabetes Care 
08100942005-0121
WARNING
• Keep new and used batteries away 
from children. See the User’s 
Manual for additional information.
• This Quick Start Guide does not replace the 
User’s Manual for your Accu-Chek Guide blood 
glucose meter. The User’s Manual contains 
important cleaning and disinfecting procedures 
and additional information.
• The meter and lancing device are for single 
patient use. Do not share them with anyone, 
including other family members! Do not use on 
multiple patients!
• All parts of the kit are considered biohazardous 
and can potentially transmit infectious 
diseases from bloodborne pathogens, even 
after you have performed cleaning and 
disinfecting.
Start Here
Quick Start Guide
For in vitro diagnostic use only
ENGLISH
Set the Meter Language
Turn the meter on by briefly 
pressing . Language appears. 
Press or to highlight the 
desired language. 
1
2
Press to set the language and 
return to Main Menu.
Overview
1 Display 
2 Back Button 
3 Up Arrow and Down Arrow 
Buttons 
4 Power/Set/OK Button 
5 Test Strip Slot with Light
6 Battery Door 
7 Micro USB Port 
8 Test Strip Ejector
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Blood Glucose Monitoring System
To find diabetes management apps 
that are compatible with your meter, 
visit www.accu-chek.com.
NOTE
• Always have a spare set of batteries.
• Battery life may vary due to factors such as 
temperature and battery manufacturer.
Connect the Accu-Chek Guide meter to the mySugr app
Using your smartphone, 
download the mySugr app 
from the App Store or Google 
Play and create your mySugr 
account. 
Turn on Bluetooth®on your 
smartphone (if it’s not on 
already).
1 2
3 4
Open the mySugr app, and 
select Connections on the 
menu. Select Accu-Chek 
Guide, and then Connect now. 
Follow the step-by-step 
directions for pairing.
After your meter is successfully 
connected to the mySugr app, 
data from your device is 
imported automatically. Now 
you can easily keep your 
diabetes data under control!
Wash and dry your hands before 
and after you perform a blood 
glucose test. 
Check the Use By date on the 
test strip container. Do not use 
test strips past the Use By date.
Remove a test strip from the 
test strip container. Close the 
cap tightly.
Insert the metallic end of the 
test strip into the meter. 
The meter turns on. Preparing 
to test appears. 
Perform a Blood Glucose Test
Press the lancing device firmly 
against the side of your fingertip 
and press the yellow release 
button to prick your finger. 
Touch the yellow edge of the test strip to the blood drop. Remove 
your finger from the test strip when Analyzing appears. Do not put 
blood on top of the test strip. 
The test result appears on the 
display in less than 4 seconds. 
 
Remove the lancing device cap. 
Point the lancet away from you. 
Slide out the ejector to release 
the lancet. 
12 43
5 6 Before you finish…
Familiarize yourself with the 
Accu-Chek Softclix lancing 
device.
1
Get a lancet from the pocket in 
the carrying case.
Remove the cap by pulling it 
straight off. Do not twist the 
cap.
Insert the lancet into the lancing 
device until it clicks.
Replace the cap on the lancing 
device. Make sure the notch on 
the cap lines up with the notch 
on the lancing device.
Adjust the lancet depth to a 
comfortable penetration level. 
Start at 2. For tougher skin, dial 
to a higher number.
Press the priming button in as 
far as it will go, like a pen. Do 
not press the release button 
while pressing the priming 
button. The release button turns 
yellow when the lancing device 
is ready.
Set the lancing device aside 
until you are ready to perform a 
fingerstick.
Ejector
Release button
Cap Priming 
button
Penetration depth
Set up the Lancing Device
2 43 5
Twist off the lancet's protective 
cap.
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