ALPHA OMEGA Neuro Omega User manual

March 2016
ALPHA OMEGA
U.S. Office:
Toll Free 1-877-919-6288
Fax [phone]
Europe Office:
Toll Free: 00-800-2-574-2111
Tel [phone]
Home Office:
Nazareth Industrial Park Building, M ount
Precipice
P.O. Box 2268 Nazareth 1612102, Israel.
Tel. [phone] Fax: [phone]
Email: [e-mail]
Website: www.alphaomega-eng.com
Neuro Omega™
Physiological Navigation System for
Neurosurgery and Neurophysiological
Medical Applications
User Manual
Revision 1.4.2

March 2016
PROPRIETARYNOTICE
This publication, or parts thereof, contains information proprietary to Alpha Omega Engineering
and may not be reproduced, recorded or transmitted in any form, by any method, for any purpose
without written permission from Alpha Omega Engineering.
Alpha Omega Engineering Ltd. makes no warranty, expressed or implied, including but not
limited to any implied warranties of merchantability or fitness for a particular purpose or use,
regarding these materials and makes such materials available solely on an “as-is” basis.
In no event shall Alpha Omega Engineering Ltd. be liable to anyone for specific, collateral,
incidental, or consequential damages in connections with or arising from purchase or use of these
materials. The sole and exclusive liability to Alpha Omega Engineering Ltd., regardless of the
form of actions, shall not exceed the purchase price of the materials described herein.
The Neuro Omega and Alpha Omega are trademarks of Alpha Omega Engineering Ltd.
For additional information on the device, including questions on infection control procedures,
please contact:
Contact Information:
Name and Address of the European
Authorized Representative:
ALPHA OM EGA ENGINEERING
Nazareth Industrial Park Building
M ount Precipice
P.O. Box 2268
Nazareth 1612102
Israel
Tel: [phone]
Fax: [phone]
Email:
[e-mail]
[e-mail]
http://www.alphaomega-eng.com
M r. Yousef Bsul
Europe Sales M anager
Alpha Omega GmbH
Ubstadter Str. 28
Ubstadt-Weiher,76698
Germany
Tel: [phone]
Fax: [phone]
Toll free: 00-800-2574-2111
Email:
[e-mail]
http://www.alphaomega-eng.com
U.S. Office: Toll Free: 1-877-919-6288, Fax: [phone]
Europe Office: Toll Free: 00-800-2-574-2111, Tel [phone]
© Alpha Omega 2015

March 2016
Contents
CHAPTER 1. Overview .............................................................................................. 9
1.1. Scope........................................................................................................................... 9
1.2. Regula tory .................................................................................................................... 9
1.2.1. Adverse Effects ....................................................................................................... 9
1.2.2. FDA System Classification .......................................................................................10
1.3. Intended Uses .............................................................................................................10
1.4. Conditions of Use .........................................................................................................11
1.5. Warnings .....................................................................................................................11
1.6. Electromagnetic Conformance.......................................................................................13
CHAPTER 2. System Description ...............................................................................17
2.1. Main Unit and Trolley ...................................................................................................17
2.2. Drive Headstage Module...............................................................................................24
2.2.1. Drive Headstage .....................................................................................................25
2.2.2. Electrode Holder and Bengun ..................................................................................26
2.2.3. Frame Adaptor .......................................................................................................27
2.2.4. Electrodes ..............................................................................................................27
2.2.5. Electrode Input Cable .............................................................................................28
2.2.6. Cannulas ................................................................................................................28
2.2.6.1. Using CRW and MicroMar Frames .............................................................29
2.2.6.2. Using Leksell and Libenger Frames ...........................................................30
2.2.6.3. Using Nexframe Frames............................................................................31
2.2.6.4. Using Starfix Frames.................................................................................32
2.3. MER Only Headstage Module ........................................................................................33
2.3.1. MER Only Headstage ..............................................................................................33
2.3.2. MER Only Electrode Input Cable ..............................................................................33
2.4. Headbox Modules .........................................................................................................34
2.5. Remote Control............................................................................................................36
CHAPTER 3. Preparing the Neuro Omega System ......................................................37
3.1. Cleaning and Sterilizing the Neuro Omega Components ..................................................37

March 2016
3.1.1. Sterilization Checklist ..............................................................................................44
3.1.2. Sterile Items ..........................................................................................................44
3.2. Setting the Electrode Starting Point ...............................................................................45
3.2.1. Setting Electrode Starting Depth Method 1 ...............................................................46
3.2.2. Setting Electrode Starting Depth Method 2 ...............................................................46
3.3. Assembling the Headstage............................................................................................51
3.4. Headbox Modules Assembly..........................................................................................59
3.4.1. Assembling the EMG Module ...................................................................................59
3.4.2. Assembling the EEG Module ....................................................................................60
3.5. Connecting External Systems ........................................................................................61
CHAPTER 4. Operation of the Neuro Omega System ..................................................63
4.1. Using the Neuro Omega System for Implanting the DBS .................................................63
4.2. Powering On the Neuro Omega .....................................................................................64
4.3. Workspace Maker.........................................................................................................64
4.3.1. Create New Workspace ...........................................................................................65
4.3.1.1. EEG Module:............................................................................................66
4.3.1.2. EMG Module ............................................................................................67
4.3.1.3. ADIO Panel ..............................................................................................68
4.3.2. Edit Workspace ......................................................................................................70
4.3.3. Delete Workspace...................................................................................................70
4.3.4. Windows Default ....................................................................................................70
4.4. Supplying Patient Info ..................................................................................................71
4.5. Selecting an Existing Patient .........................................................................................72
4.6. Neuro Omega Interface Navigation ...............................................................................73
4.6.1. Toolbar ..................................................................................................................73
4.6.2. Workspace .............................................................................................................75
4.6.2.1. Closing and Opening a Workspace Window................................................76
4.6.2.2. Popping a Workspace Window In and Out ..................................................77
4.6.2.3. Restoring the Workspace Layout ...............................................................77
4.6.2.4. Clearing All Workspace Windows...............................................................77
4.6.2.5. Pausing Workspace Windows....................................................................77
4.6.3. Trajectory Graph ....................................................................................................78

March 2016
4.6.4. Viewing System Diagnostics ....................................................................................79
4.7. Event Definition ...........................................................................................................80
4.7.1. Defining Events ......................................................................................................80
4.7.2. Editing Events ........................................................................................................82
4.7.2.1. Deleting an Event......................................................................................83
4.7.3. Events Definition Table ...........................................................................................83
4.8. Verifying Diagnostic Indicators ......................................................................................84
4.9. Configuring Drive and Save Settings ..............................................................................84
4.10. Verifying Starting Depth ...............................................................................................86
4.10.1. Drive Headstage Module .........................................................................................86
4.10.2. MER Only Headstage Module...................................................................................86
4.11. Creating a New Trajectory ............................................................................................87
4.12. Setting Drive Position ...................................................................................................89
4.13. Checking Impedance ....................................................................................................90
4.14. Manipulating the Drive Headstage .................................................................................91
4.15. Monitoring Activity .......................................................................................................92
4.15.1. Monitoring Channels ...............................................................................................92
4.15.1.1. Adjusting Channel Scales ..........................................................................94
4.15.1.2. Toggling a Channel’s Sound ......................................................................95
4.15.1.3. Grounding a Channel ................................................................................95
4.15.1.4. Changing a Channel Name........................................................................96
4.15.1.5. Using the Information Line.........................................................................96
4.15.1.6. Applying a Recording Reference to a Contact .............................................96
4.15.2. Monitoring Digital Input Channels ............................................................................97
4.15.3. Monitoring Micro Segmentation Spike Sorting ...........................................................98
4.15.3.1. Main Segmentation Window Navigation......................................................98
4.15.3.2. Defining Spike Sorting Templates ............................................................ 100
4.15.3.3. Defining the Template Variation ............................................................... 102
4.15.3.4. Adding Include Windows ......................................................................... 104
4.15.3.5. Monitoring the Spike Templates ............................................................... 105
4.15.4. Monitoring Spikes in the Spikes Raster Graph .........................................................106
4.15.5. Monitoring Spikes in the Interspike Interval (ISI) Graph..........................................108

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4.15.6. Monitoring EEG signals in Color Density Spectral Array Graph. .................................109
4.16. OPRA ........................................................................................................................112
4.16.1. Assessing OPRA Feedback.....................................................................................112
4.16.2. OPRA Best Practices .............................................................................................113
4.17. User Events ...............................................................................................................114
4.17.1. Marking Events from the Events Control Panel ........................................................114
4.17.2. Marking Events from the Events Definition Table ....................................................115
4.17.3. Adding Remarks ...................................................................................................115
4.18. Trajectory Printing .....................................................................................................116
4.18.1. Printing the Selected Track....................................................................................116
4.18.2. Printing an Active Track ........................................................................................117
4.19. Saving Data to the Log File .........................................................................................119
4.20. Stimulation ................................................................................................................119
4.20.1. Setting Up Stimulation ..........................................................................................120
4.20.2. Applying Stimulation to the Patient from the Toolbar ..............................................122
4.20.3. Monitoring Stimulation in the Current Monitor Window ............................................123
4.21. Defining and Monitoring the Evoked Potential ..............................................................124
4.22. Defining and Monitoring the Peristimulus Histogram (PSTH) .........................................128
4.23. Operation of the Neuro Omega Player Mode ................................................................131
4.23.1. Player Offline Mode ..............................................................................................131
4.24. Dry Run: DBS Electrode Handling ................................................................................136
CHAPTER 5. Advanced Capabilities .........................................................................141
5.1. Advanced Over view ....................................................................................................141
5.2. Filtering and Sampling Properties ................................................................................141
5.2.1. Controlling Micro Filtering and Sampling Properties .................................................142
5.2.2. Controlling Macro Filtering and Sampling Properties ................................................144
5.2.3. Controlling EEG Filtering and Sampling Properties ...................................................146
5.2.4. Controlling EMG Filtering and Sampling Properties ..................................................148
5.2.5. Changing Channel Names .....................................................................................150
5.3. Logging Options.........................................................................................................151
5.3.1. Defining Logging Options ......................................................................................151

March 2016
5.3.2. Saving Files by Digital Triggers ..............................................................................156
5.4. Channel Routing of Analog Outputs .............................................................................156
5.4.1. Routing a Pre-Selected Channel.............................................................................157
5.4.2. Routing the Channel in Focus ................................................................................158
5.5. Editing a Channel Contact...........................................................................................158
5.6. Defining Impedance Settings ......................................................................................158
CHAPTER 6. Technical Specifications ......................................................................160
6.1. General .....................................................................................................................160
6.2. Sorting ......................................................................................................................161
6.3. Drive Headstage/MER Only Headstage ........................................................................161
6.4. Headbox Modules for EEG/EMG...................................................................................165
6.5. Headbox Modules Stimulation for EMG ........................................................................166
6.6. General Purpose Analog Inputs ...................................................................................167
6.7. General Purpose Analog Outputs .................................................................................168
6.8. Audio Outputs............................................................................................................168
6.9. General Purpose Single Bit Digital Inputs .....................................................................169
6.10. General Purpose Digital Input 16-bit Ports ...................................................................169
6.11. General Purpose Digital Outputs .................................................................................169
6.12. Analog Digital Inputs and Outputs Pinout ....................................................................170
6.12.1. ADD DIG-OUT Pinout ............................................................................................171
6.12.2. ADD ANALOG-IN Pinout ........................................................................................171
6.12.3. ADD DIG-IN Pinout ...............................................................................................172
6.12.4. PORT-1 16 BIT, PORT-2 16 BIT Pinout...................................................................172

Overview
Neuro Omega User Manual
for Medical Applications V1.4.2
Page 9
CHAPTER 1. OVERVIEW
The Neuro Omega is a physiological navigation system intended for different
neurosurgery and neurophysiological clinical applications, including recording from and
stimulating brain motor and sensory neurons to accurately navigate for neurosurgery
target localization in treatment of movement disorders and to aid in the placement of
depth electrodes.
The system records and stimulates brain peripheral-nerve electrical activity from various
areas of the brain (deep structures and surface areas).
The device is also designed to measure bioelectric signals produced by muscles (EMG)
and stimulate peripheral nerves to aid in the diagnosis and prognosis of neuromuscular
disease for target localization surgeries for motor movement disorders or for intra-
operative skeletal muscles activity. This can be done with recording or stimulation.
The device may also be used to measure and record the electrical activity of the patient's
brain, obtained by placing two or more electrodes on the head (EEG). This is for cortical
and surface electrical activity levels of the brain.
The device is also designed for temporary monitoring of brain electrical activity from
deep or cortical brain during neurosurgery in the operating room or outside the clinical
environment.
1.1. SCOPE
The purpose of the Neuro Omega Medical Manual is to provide information for the use of
the Neuro Omega system in medical treatment.
Warning:
Do not use this manual for conducting research procedures.
1.2. REGULATORY
1.2.1. Adverse Effects
The possible adverse effects relating to Stereotactic Neurosurgery are:
The possibility of intracranial hemorrhage associated with the introduction of
probes into the brain.
Visual field impairment with optic tract injuries.

Overview
Neuro Omega User Manual
for Medical Applications V1.4.2
Page 10
Contra lateral motor deficit with corticospinal injury.
1.2.2. FDA System Classification
Product Code: GZL
Subsequent Product Code: GWF, IKN, GWQ
CFR Section: 21 CFR 882.1330
Regulation Name: Depth electrode
Subsequent Regulation Names:
Electroencephalograph
Stimulator
Electrical
Evoked response
Electromyography
Diagnostic
Trade Name: Neuro Omega System
Common Name: Intraoperative neurophysiological recording and
stimulating device
Classification: Class II
1.3. INTENDED USES
The Neuro Omega System is intended for the following:
Assisting neurosurgeons in the operating room during functional
neurosurgery.
Recording from and stimulating brain motor and sensory neurons to aid in
the placement of depth electrodes.
Monitoring, recording, and displaying the bioelectric signals produced by
muscles.
Stimulating peripheral nerves.
Monitoring, recording, and displaying the electrical activity produced by
nerves (EMG) for aiding the clinician in the diagnosis and prognosis of
neuromuscular disease.
Measuring and recording the electrical activity of the patient's brain obtained
by placing two or more electrodes on the head (EEG).

Overview
Neuro Omega User Manual
for Medical Applications V1.4.2
Page 11
1.4. CONDITIONS OF USE
The device may be used by medical personnel within a hospital, laboratory, clinic, or
nursing home setting, or outside of a medical facility under direct supervision of a
medical professional. The device may also be placed in the intensive care unit or
operating room for continuous recording.
The following are the Neuro Omega system use conditions:
Environment:
Conditions of visibility:
Ambient luminance range: Normal
Viewing distance: N/A
Viewing angle: N/A
Physical:
Temperature range: 0°C to +40°C
Relative humidity range: 10% - 80%, non-condensing
Ambient pressure range: 500 hPa to 1060 hPa
Background sound pressure level: Normal
Frequency of Use: As per specific case
Mobility: Mobile
1.5. WARNINGS
Warnings:
Only qualified personnel, who have been trained by Alpha Omega Ltd.,
should be allowed to operate this equipment.
Any modifications made to the equipment without explicit approval from
Alpha Omega Ltd., voids warranty and service contract obligations, and
poses a potential safety threat to both operators and patients.
Do not install any software packages (Matlab, C++, SDK software or other)
on the system unless provided by Alpha Omega Ltd. for the explicit use on
the Neuro Omega.
Neuro Omega system and Neuro Omega drive headstage should be
connected to Alpha Omega NeuroProbes for recording and stimulation
External systems connected to the Neuro Omega must be independently
isolated, or powered through the trolley, as this has its own isolation
transformer.
Possible hazard caused by the summation of leakage currents when several
items of equipment are interconnected.

Overview
Neuro Omega User Manual
for Medical Applications V1.4.2
Page 12
The Neuro Omega system should be placed outside of the patient
environment or any area that can, intentionally or unintentionally, come in
contact with the patient.
A thorough understanding of the technical principles, clinical applications,
and risks associated with this treatment is necessary before using this
system. Please read this entire manual before attempting to activate the
system. Completion of the training program is required prior to use of the
Neuro Omega system.
The Neuro Omega does not incorporate means to protect the patient
against burns when used with high frequency surgical equipment.
The analog and digital input output panel (ADIO) is not an applied part, and
therefore should not be connected to the patient without proper electrical
isolation.
Cautions:
US federal law restricts the sale of this device to or on the order of a
physician.
Discard according to the local regulations and law.
Notes:
Some of the Neuro Omega system components can be provided either non-
sterile or sterile. Please refer to Preparing the Neuro Omega System for
detailed sterilization instructions of system and accessories.
It is the user’s responsibility to qualify any deviations from the
recommended method of processing.
There are no expected hazards resulting from simultaneous use of other
patient-connected medical electrical equipment, for example, a cardiac
pacemaker or other electrical stimulators.
Please contact the manufacturer or local distributor to request a copy of
the insulation diagram if needed.
The Neuro Omega can be operated normally after the interruption of
supply mains.

Overview
Neuro Omega User Manual
for Medical Applications V1.4.2
Page 13
1.6. ELECTROMAGNETIC CONFORMANCE
The following tables contain information on electromagnetic emissions for guidance and
manufacturer’s declaration:
Guidance and Manufacturer’s Declaration – Electromagnetic Emissions
Guidance and Manufacturer’s Declaration – Electromagnetic Immunity
Recommended Separation Distances between Portable and Mobile RF
Communications Equipment and the Neuro Omega
Notes:
This product has been tested and found to comply with the limits for Class
A Medical Device according to IEC 60601-1 and IEC 60601-1-2 Standards.
The limits for Class A equipment were derived for medical environments to
provide reasonable protection against interference with licensed
communication and medical equipment.
This product must be installed and put into service according to the EMC
information provided in the tables below.
Portable and mobile RF communications equipment can affect this product.
Warnings:
This is a Class A product. This product is intended for use by healthcare
professionals only. This equipment/system may cause radio interference or
may disrupt the operation of nearby equipment. It may be necessary to
take mitigation measures, such as re-orienting or relocating the Neuro
Omega or shielding the location.
The use of accessories, transducers, and cables other than those specified
by the manufacturer may result in increased emissions or the decreased
immunity of the Neuro Omega.
The Neuro Omega should not be used adjacent to or stacked with other
equipment. If adjacent of stacked use is necessary, the Neuro Omega
should be observed to verify normal operation in the configuration in which
it will be used.
The Neuro Omega is intended for use in the electromagnetic environment specified in
Table 1. The user of the Neuro Omega should assure that it is used in such an
environment.

Overview
Neuro Omega User Manual
for Medical Applications V1.4.2
Page 14
Table 1: Guidance and Manufacturer’s Declaration – Electromagnetic
Emissions
Emissions Test
Compliance
Electromagnetic Environment Guidance
RF emissions CISPR 11
Group 1
The Neuro Omega uses RF energy only for its internal
function. Therefore, its RF emissions are very low and are
not likely to cause any interferences in nearby electronic
equipment.
RF emissions CISPR 11
Class A
The Neuro Omega is suitable for use in all establishments
other than domestic, and may be used in domestic
establishments and those directly connected to the public
low-voltage power supply network that supplies buildings
used for domestic purposes.
Harmonic emissions
IEC 61000-3-2
Class A
Voltage fluctuations/flicker
emissions
IEC 61000-3-3
Complies
The Neuro Omega is intended for use in the electromagnetic environment specified in
Table 2. The customer or the user of the Neuro Omega should assure that it is used in
such an environment.
Table 2: Guidance and Manufacturer’s Declaration – Electromagnetic
Immunity
Immunity Test
IEC 60601 test
level
Compliance
Electromagnetic Environment Guidance
Electrostatic
discharge (ESD)
IEC 61000-4-2
±6kV contact
±8kV air
±6kV contact
±8kV air
Floors should be wood, concrete or ceramic
tile. If floors are covered with synthetic
material, the relative humidity should be less
than 30%.
Electrostatic fast
transient/burst
IEC 61000-4-4
±2kV for power
supply lines
±1kV for
input/output
lines
±2kV for power
supply lines
±1kV for
input/output
lines
M ains power quality should be that of a typical
commercial or hospital environment.
Surge
IEC 61000-4-5
±1kV line(s) to
line(s)
±2kV line(s) to
earth
±1kV line(s) to
line(s)
±2kV line(s) to
earth
M ains power quality should be that of a typical
commercial or hospital environment.
Voltage dips, short
interruptions and
voltage variations on
power supply input
lines
IEC 61000-4-11
<5% UTfor 0.5
cycles
40% UTfor 5
cycles
70% UTfor 25
cycles
<5% UTfor 0.5
cycles
40% UTfor 5
cycles
70% UTfor 25
cycles
M ains power quality should be that of a typical
commercial or hospital environment. If the
user of the Neuro Omega requires continued
operation during power mains interruptions, it
is recommended that the Neuro Omega be
powered from an uninterruptible power supply
(UPS) battery.

Overview
Neuro Omega User Manual
for Medical Applications V1.4.2
Page 15
<5% UTfor 5 s
<5% UTfor 5 s
Power frequency
(50/60 Hz) magnetic
field
IEC 61000-4-8
3 A/m
3 A/m
M ains power quality should be that of a typical
commercial or hospital environment.
Conducted RF
IEC 61000-4-6
Radiated RF
IEC 61000-4-3
3 Vrms 150 kHz
to 80 M Hz
3 V/m 80 MHz
to 2.5 GHz
3 Vrms 150 kHz
to 80 M Hz
3 V/m 80 MHz
to 2.5 GHz
Portable and mobile RF communications
equipment should be used no closer to any
part of the Neuro Omega, including cables,
than the recommended separation distance
calculated from the equation applicable to the
frequency of the transmitter.
Recommended separation distance:
d=1.2√P
d=1.2√P 80 MHz to 800 MHz
d=2.4√P 800 MHz to 2.5GHz
Where P is the maximum output power rating
of the transmitter in watts (W) according to
the transmitter manufacturer and dis the
recommended separation distance in meters
(m).
Field strength from fixed RF transmitters, as
determined by an electromagnetic site
survey,1should be less than the compliance
level in each frequency range.2
Interference may occur in the vicinity of
equipment marked with the following symbol:
Notes:
At 80 MHz and 800 MHz, the higher frequency range applies.
These guidelines may not apply in all situations. Electromagnetic
propagation is affected by absorption and reflection from structures,
objects and people.
1. Field strength fromfixed transmitters, such as base stations for radio (cellular/cordless) telephones and land mobile
radios, amateur radio, AM and FM radio broadcast and TV broadcast cannot be predicted theoretically with accuracy.
To assess the electromagnetic environment due to fixed RF transmitters, an electromagnetic site survey should be
considered. If the measured field strength in the location in which the Neuro Omega is used exceeds the applicable
RF compliance level above, the Neuro Omega should be observed to verify normaloperation. If abnormal
performance is observed, additionalmeasures may be necessary, such as re-orienting or relocating the Neuro
Omega.

Overview
Neuro Omega User Manual
for Medical Applications V1.4.2
Page 16
2. Over the frequency range 150 kHz to 80 MHz, field strength should be less than 3 V/m.
The Neuro Omega is intended for use in the electromagnetic environment in which
radiated RF disturbances are controlled. The customer or the user of the Neuro Omega
can help prevent electromagnetic interference by maintaining a minimum distance
between portable and mobile RF communications equipment (transmitters) and the
Neuro Omega as recommended in Table 3, according to the maximum output power of
the communications equipment.
Table 3: Recommended Separation Distances between Portable and
Mobile RF Communications Equipment and the Neuro Omega
Rated maximum output
power of transmitter
W
Separation distance according to frequency of transmitter
m
150 kHz to 80 M Hz
d=1.2√P
80 M Hz to 800 M Hz
d=1.2√P
800 M HZ to 2.5 GHz
d=2.4√P
0.01
0.12
0.12
0.24
0.1
0.37
0.37
0.74
1
1.2
1.2
2.4
10
3.7
3.7
7.4
100
12
12
24
For transmitters rated at maximumoutput power not listed above, the recommended separation distance din meters (m)
can be estimated using the equation applicable to the frequency of the transmitter, where pis the maximum output
power rating of the transmitter in watts (W) accordingto the transmitter manufacturer.
Notes:
At 80 MHz and 800 MHz, the separation distance for the higher frequency
range applies.
These guidelines may not apply in all situations. Electromagnetic
propagation is affected by absorption and reflection from structures,
objects and people.

System Description
Neuro Omega User Manual
for Medical Applications V1.4.2
Page 17
CHAPTER 2. SYSTEM DESCRIPTION
The Neuro Omega system consists of the following units:
Main Unit and Trolley: The Main Unit contains all interfaces with analog and
digital inputs and outputs unit, as well as all connections to the different
modules. The Main Unit, the screens and speakers, and the computer are all
fitted on the trolley.
Drive Headstage Module: Includes the Drive Headstage, which contains the
mechanism that manipulates the electrode, records from the electrode, and
provides stimulation
MER Only Headstage Module: Includes the MER Only Headstage, which
contains the mechanism that records from the electrode and provides
stimulation
Headbox Modules: Of two types. One allows for recording EMG signals, and
one allows for recording EEG signals.
Remote Control: Allows for easy system operation, including manipulating
the electrode and providing stimulation through the Drive Headstage.
2.1. MAIN UNIT AND TROLLEY
The Main Unit is the processing core of the system, and is attached to the trolley. The
Main Unit is comprised of the following three panels:
The front panel (Figure 1) houses LEDs to display Neuro Omega’s power
state. When functioning properly, the green LED on the top is lit and there
are at least 3 cyclically flashing lights in the center of the panel.

System Description
Neuro Omega User Manual
for Medical Applications V1.4.2
Page 18
Figure 1: Front Panel
On the right side is the Modules panel (Figure 2), which houses the following
connections:
Connection
Location
Reference
Drive Headstage /
M ER O nly Headstage
green
See section 2.2 for information
about the Drive Headstage and
the Drive Headstage module.
See section 2.3 for information
about the M ER Only Headstage.
Headbox modules
according to
configuration
cascading up, multicolored
See section 2.4for information
about the Headbox modules.
Remote
Small, yellow
See section 2.5 for information
about the remote.

System Description
Neuro Omega User Manual
for Medical Applications V1.4.2
Page 19
Figure 2: Modules Panel
On the left is the Analog/Digital Input/Output panel (ADIO panel) (Figure 3),
which houses the external connections, through BNC and D-Type, as follows:
ANALOG-IN: Eight analog input ports, sampled in 12-bit ADC, and
acquired in continuous mode
ANALOG-OUT: Eight analog output ports, sampled in 16-bit DAC, for
rerouting any signal to an external device
DIG-IN: Four digital input ports, sampled as single bits or 16-bit ports
DIG-IN: Two digital input ports, sampled as 16-bit ports
DIG-OUT: Eight digital output ports for future use

System Description
Neuro Omega User Manual
for Medical Applications V1.4.2
Page 20
Figure 3: ADIO Panel
The bottom of the Main Unit (Figure 4, as seen from under the main unit) houses the
following connections:
Three Ethernet connections for communication between the Main Unit and
the computer
Connection to the computer for the remote control via USB
Two audio output connections
Power switch for main unit