Chemyx Fusion 4000 User manual

FUSION 4000 & 6000
USER MANUAL

2
EU Declaration of Conformity (DoC)....................................................................................................................6
General Description...............................................................................................................................................7
Warranty and Repair Information........................................................................................................................9
Warranty Information................................................................................................................................9
Repair Facilities and Parts........................................................................................................................10
Dead Pixel Policy......................................................................................................................................10
Serial Numbers.........................................................................................................................................10
Calibrations.........................................................................................................................................10
ProductOverview..................................................................................................................................................11
Principle of Operation..............................................................................................................................11
Controlled Elements.................................................................................................................................12
 Specications...............................................................................................................................................15
Pump Setup...........................................................................................................................................................17
 PoweringOn/OthePump....................................................................................................................17
Loading a Syringe.....................................................................................................................................18
 AdjustingtheSafetyNut/StallRod........................................................................................................21
Pump Operation......................................................................................................................................22
Mode Selection Screen............................................................................................................................24
 Pressure&TemperatureSettings(Fusion6000only).......................................................................25
Basic Mode............................................................................................................................................................26
Syringe Selection......................................................................................................................................26
Volume......................................................................................................................................27
 Infusion/Withdrawal.................................................................................................................................28
Flow Rate..................................................................................................................................................28
Start-Time Delay......................................................................................................................................29
Step Loop..................................................................................................................................................29

3
Options...........................................................................................................................................................30
Flow-Rate Units........................................................................................................................................30
Options....................................................................................................................................31
Enable Volume Lock.................................................................................................................................31
Multi-Step Mode...................................................................................................................................................32
Setup.......................................................................................................................................32
Syringe Selection.....................................................................................................................................32
Total Steps................................................................................................................................................33
Loop All.....................................................................................................................................................33
Sub-Loops...........................................................................................................................................33
Flow-Rate Units........................................................................................................................................34
Step Parameters...................................................................................................................................................34
 Volume.......................................................................................................................................35
Pump Control.......................................................................................................................................................36
System Settings....................................................................................................................................................39
Pump Control by Computer...............................................................................................................................41
Cable Requirements............................................................................................................................................41
Connecting............................................................................................................................................................41
COM Port Settings....................................................................................................................................42
Pump Commands................................................................................................................................................43
ChemyxPumpControllerPrograms.................................................................................................................48
Pump Maintenance.............................................................................................................................................49
 Lubricating the Pump.............................................................................................................................49
Lubrication Instructions.........................................................................................................................49
Approved Lubricants...............................................................................................................................49
PumpAccessories................................................................................................................................................50

4
Appendices.................................................................................................................................................52
 Appendix A: Syringe Volume/Diameter Reference............................................................................52
 AppendixB:AvailableParts....................................................................................................................56
 AppendixC:ContactInformation...........................................................................................................57

5
INTELLECTUAL PROPERTY
AllIntellectualProperties,asdenedbelow,ownedbyorwhichisotherwisethepropertyofChemyxInc.oritssuppliersrelatingtotheChemyxsyringepumps,includingbutnotlimitedto,accessories,
partsorsoftwarerelatingthereto(ChemyxSyringePumps),areproprietarytofederalandstatelaws,andinternationaltreatyprovisions.IntellectualPropertyincludesbutisnotlimitedto,inventions
(patentableorunpatentable),patents,tradesecrets,copyrights,software,rmware,computerprograms,andrelateddocumentationandotherworksofauthorship.Moreover,youagreethatyouwill
not,andwillnotattemptto,modify,preparederivativeworksof,reverseengineer,disassembletheChemyxsyringepumps,decompileorotherwiseattempttocreatesourcecodefromtherelated
software/rmware.NotitletoorownershipinIntellectualPropertyistransferredtoyou.AllapplicablerightsoftheIntellectualPropertyshallremainwithChemyxanditssuppliers.

6
Declaraon of Conformity
The PDF version of the latest DoC can be downloaded at www.chemyx.com/support
EU Declaration of Conformity (DoC)
We:
Declare that the DoC is issued under the sole responsibility of the manufacture and belongs to
the following product(s):
All Syringe Pump Model Names, including:
- Fusion 100
- Fusion 200
- Fusion 4000
- Fusion 6000
- Nexus 3000
- Nexus 6000
- NanoJet StereoTaxic
- Fusion 100T
- OEM
The object of the declaration described above is in conformity with the relevant Union harmo-
nization legislation:
The technical documentation required to demonstrate that the products meet the
requirements of the LV and EMC directives has been compiled and is available for
inspection by the relevant enforcement authorities.
Signature on behalf of manufacturer:
Authority:
Date:
Chemyx, Inc.
10905 Cash Road
Stafford, TX 77005
[phone]
[e-mail]
- EN 613326-1: 2013 Electrical Components for measurement, control, and
laboratory use - EMC requirements - Part 1: General Requirements
- EN 61010-1: 2010 European Low Voltage Directive 2014/35/EU Safety
requirements for electrical equipment for measurement, control, and
laboratory use Part 1: General Requirements
- Directive 2011/65/EU of the European Parliament and of the Council of 8 June
2011 on the restriction of the use of certain hazardous substances in electrical
and electronic equipment.
Attention!
The attention of the specifier, purchaser, installer, or user is drawn to special measures and limitations to use which
must be observed when these products are taken into service to maintain compliance with the above directives.
Details of these special measures and limitations to use are available on request,
and are also contained in the product manuals.
Jeff Wu, Senior Engineer, Chemyx, Inc.
Date: March 1, 2018

7
General Descripon
              

manufacturer; warranty coverage provided by the equipment may be dropped as a result.
CHEMYX PRODUCTS ARE NOT APPROVED FOR CLINICAL USE ON HUMANS.

power converter from 220V to 110 V while in the 220V environment or vice versa.
The product should be properly grounded.
USE PROPER POWER SUPPLY
GROUND PRODUCT
Safety Informaon

connectors on or in the product.



DO NOT OPEN THE PUMP
DO NOT OPERATE WITH SUSPECTED FAILURES

PINCH HAZARD
Read all labels on the product to ensure proper usage.
OBSERVE ALL WARNING LABELS ON PRODUCT

CHEMYX IS NOT RESPONSIBLE FOR SYRINGE DAMAGE



CHEMYX IS SAFETY PRECAUTIONS

8
Warranty and Repair Informaon



         ) before returning a product.


Chemyx Inc.

Warranty Informaon
Improper or inadequate maintenance or operation.
 Unauthorizedmodicationormisuseoftheproduct.
 Operationoutsidetheelectricalspecicationsfortheproduct.
 Operationoutsidethetemperaturespecicationsfortheproduct.
 User-inducedinternalandexternalcontaminationsoftheinstrument.
Failure to use proper surge protection.
 Improperproductreturn,packaging,andshipping
Removing serial number from syringe pump

9

us at 
number to you.

Chemyx Returns

                   






number label will void the warranty.
               


not responsible for errors generated from syringes.
Repair Facilies and Parts
Dead Pixel Policy
Serial Numbers
Calibraons

10
Product Overview



 

years of constant and reliable service.






into the syringe.
PRINCIPLE OF OPERATION

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





 

     

Controlled Elements
Syringe Holder Block
Safety Rod Lead Screw
PusherBlock
Syringe Clamp
SyringeChannels
Fusion 6000 pump components

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                


elements by touch only requires a small amount of pressure; however, please do not use sharp objects as they may damage
the screen.




running, paused, or stopped.
CONTROLS
Navigation Keypad
Front Panel of Pump
 Pump Controls  Numeric Keypad

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



channel in place during infusion and withdrawal.
         

of both infusion and withdrawal on a single pump channel.


the syringe in place during both infusion and withdrawal.
Bracket Release Knob
Bracket Release Knob
Flange Retaining Bracket
Flange Retaining Bracket
Plunger Retaining Bracket
Plunger Retaining BracketBracket Release Knob
FUSION 4000 SPECIFIC COMPONENTS
FUSION 6000 SPECIFIC COMPONENTS

14
Specicaons
Specicaon Fusion 4000 Fusion 6000
Movement Modes Infusion/
Withdrawal
Infusion/
Withdrawal
SyringeSizes
W(Min/Max) 0.5μL/140mL 0.5μL/255mL
Flow Rate Range (Smallest Syringe) 0.0001 to
1.08μL/min
0.0001 to
1.5679μL/min
Flow Rate Range (Largest Syringe) 0.0002 mL/min
to 128 mL/min
0.0002 mL/min
to 128 mL/min
DriveMechanism 0.9°steppermotorwith
1/128 microstepping
0.9°steppermotorwith
1/48 microstepping
Step Resolution 0.012μm/step 0.046μm/step
Nominal
Linear Force 29kg(65lbs) 227kg(500lbs)
Accuracy ±<0.35% ±<0.35%
Reproducibility ±<0.05% ±<0.05%
Operation Temp 4°C to 40°C
(40°F to 104°F)
4°C to 40°C
(40°F to 104°F)
Storage Temp -10°C to70°C
(14°Fto158°F)
-10°C to 70°C
(14°Fto158°F)

15
Specicaons (Connued)
Specicaon Fusion 4000 Fusion 6000
  
Data Ports




 28cm (11in) 28cm (11in)
Width  26cm (10in)
  
Weight  
  

16
Pump Setup



power supply.
 

        
currently installed on the pump at the top of the screen.
       
seconds as indicated by the countdown on the right of the
startup screen.
        
last mode the pump was in.
Powering On/O the Pump

17




however, some use cases may require syringes that are more accurate and durable.
Loading a Syringe
FUSION 4000
2
3
14
1. 
2. 
 

 

secure the syringe in place.
safety collar
angebracketknob
pusherblockknob
clamp

18
57
68
 

6.                      

 
8. 

plunger bracket knob
pusherblockknob
plunger bracket knob
angebracketknob

19
1. 

2. 


         


       
screw the syringe clamp to secure the syringe in place.
 

syringe plunger.
FUSION 6000
2
1
3
567
8
 


6. 

syringe plunger. The plunger cap for the syringe should
         

        

8.        
        
        
place.
safety rod
pusherblock
clamp
plunger bracket knob pusherblock plunger bracket knob
angebracketknob

20







hits the safety mechanism and can no longer move forward, the pump will stop running, emit a long beep, and enter

Adjusng the Safety Nut/ Stall Rod

         

safety collar allows for the collar to be slid freely along the



top of syringe plunger when fully depressed.
The Fusion 6000 uses a stall rod instead of a collar to limit
        


set such that the length of the bar exposed on the right

the top of a fully depressed syringe plunger to the edge



FUSION 4000
FUSION 6000
Cauon:



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
