Franklin HAD-3038 User manual


HAD-3038
Medical Book Card
User’s Guide

MBS
Medical Book System™
HANDBOOK
OF
ADVERSE
DRUG
INTERACTIONS
The Medical Letter

20
Quick Reference Guide
To Start Using a Book Card
1. Install the book card in a slot in the
back of the Medical Book System
platform.
2. Turn the platform on.
3. If needed, press
CARD
and then
use the or to highlight its
icon.
4. Press
ENTER
to select it.
To Find Drug Interactions
1. Press
CLEAR
.
2. Highlight a drug by typing its name
or pressing or and then press
ENTER
to select it.
3. Select more drugs by highlighting
them and pressing
ENTER
.
4. Press
SEARCH
.
5. Highlight an interaction, if any, and
press
ENTER
to view it.
To Find All Other Drug Interactions
1. Press
CLEAR
.
2. Highlight a drug by typing its name
or pressing or and then press
ENTER
to select it.
3. If needed, select more drugs by
highlighting them and pressing
ENTER
.
4. Press
MORE
.
5. Highlight an interaction, if any, and
press
ENTER
to view it.
To Find a Glossary Entry
1. Press
CLEAR
.
2. Highlight a drug by typing its name
or pressing or .
3. Press
SPEC
.
4. Use ,
DN
, or
SPACE
to scroll.
5. Press
BACK
to go back.

1
READ THIS LICENSE AGREEMENT BEFORE USING THE MEDICAL BOOK
SYSTEM.
YOUR USE OF THE MEDICAL BOOK SYSTEM DEEMS THAT YOU ACCEPT
THE TERMS OF THIS LICENSE. IF YOU DO NOT AGREE WITH THESE
TERMS, YOU MAY RETURN THIS PACKAGE WITH PURCHASE RECEIPT TO
THE DEALER FROM WHICH YOU PURCHASED THE MEDICAL BOOK SYS-
TEM AND YOUR PURCHASE PRICE WILL BE REFUNDED. The MEDICAL
BOOK SYSTEM means he sof ware produc , hardware, and documen a ion found in
his package and FRANKLIN means Franklin Elec ronic Publishers, Inc.
LIMITED USE LICENSE
All righ s in he MEDICAL BOOK SYSTEM remain he proper y of FRANKLIN.
Through your purchase, FRANKLIN gran s you a personal and nonexclusive license o
use he MEDICAL BOOK SYSTEM. You may no make any copies of he MEDICAL
BOOK SYSTEM or of he preprogrammed da a s ored herein, whe her in elec ronic or
prin forma . Such copying would be in viola ion of applicable copyrigh laws. Fur her,
you may no modify, adap , disassemble, decompile, ransla e, crea e deriva ive works
of, or in any way reverse engineer he MEDICAL BOOK SYSTEM. You may no ex-
por or re-expor , direc ly or indirec ly, he MEDICAL BOOK SYSTEM wi hou com-
pliance wi h appropria e governmen al regula ions. The MEDICAL BOOK SYSTEM
con ains Franklin’s confiden ial and proprie ary informa ion which you agree o ake
adequa e s eps o pro ec from unau horized disclosure or use. This license is effec ive
un il ermina ed. This license ermina es immedia ely wi hou no ice from FRANKLIN
if you fail o comply wi h any provision of his license.
License Agreement

2
Contents
➤ About Book Card Compatibility
IMPORTANT This book card can be
used only wi h he Medical Book Sys-
em
™
pla form and will no func ion in any
o her Franklin BOOKMAN
®
pla form.
The Medical Book Sys em pla form
can use Franklin BOOKMAN book
cards as well as Medical Book Sys em
book cards. However, Franklin BOOK-
MAN pla forms canno use Medical
Book Sys em book cards.
➤ For More Information
To learn more abou he Medical Book
Sys em or o her produc s from Frank-
lin Elec ronic Publishers, call 800-665-
5450 or visi he Franklin Web si e a
www.franklin.com.
Introduction to the HADI.............. 3
Key Guide..................................... 4
Installing Book Cards .................. 5
Selecting a Book .......................... 6
Changing the Settings ................. 6
Viewing a Demonstration ............ 7
Finding Drug Interactions ........... 7
Using the Interactions Menu ..... 10
Using the Glossary .................... 11
Highlighting Search Words ....... 11
Reading Special Markers........... 12
Looking Up Words
in Other Books ........................... 13
Resetting the Medical Book
System........................................ 13
Book Card Care.......................... 14
Specifications and Patents ....... 14
Limited Warranty (U.S. only) ..... 15
Limited Warranty (outside U.S.) 16
FCC Notice ................................. 17
Index ........................................... 18

3
Introduction to the HADI
This handbook offers a quick guide o possible
adverse effec s of drug in erac ions, wi h brief
recommenda ions for precau ionary measures.
Pairs of in erac ing drugs are lis ed alphabe i-
cally, followed by he adverse in erac ion, i s
mechanism (in paren heses), references and
recommenda ions for clinical managemen .
These lis ings are usually based on clinical re-
por s. In erac ions lis ed for groups of drugs
(such as “cephalosporins” or “an idepressan s,
ricyclic”) may no have been repor ed for ev-
ery drug in he group; known excep ions o he
in erac ion are no ed.
I is no possible o de ermine he frequency of
mos in erac ions. When an in erac ion is docu-
men ed by one or wo case repor s ra her han
clinical s udies or repor s in many pa ien s, he
year of each repor is given as some indica ion of
frequency.
Repor s of in erac ions be ween more han wo
drugs have begun o appear in he medical li era-
ure. Where hese have been documen ed, hey
are no ed in he commen s under in erac ing pairs
of drugs.
CRITERIA FOR LISTING INTERAC-
TIONS –– New adverse in erac ions are con inu-
ally being repor ed; he absence of a lis ing in his
book does no necessarily mean ha drugs will
no in erac when given concurren ly. In erac ions
ex rapola ed from animal s udies or from in erac-
ions repor ed wi h rela ed drugs, may no be in-
cluded here.
In erac ions be ween general anes he ics and
drugs likely o be adminis ered during surgery,
such as au onomic drugs and local anes he ics, are
no included. In erac ions useful in herapy, such
as he increased plasma concen ra ion of penicil-
lin wi h concurren use of probenecid, are also no
lis ed. Drug combina ions should be looked up
under heir componen s.
Common addi ive effec s, such as occur wi h use
of wo an ihyper ensive agen s or wo cen ral-ner-
vous-sys em depressan s or wo drugs ha affec
blood clo ing, are generally no lis ed. Effec s ex-
pec ed from he mechanism of a drug’s ac ion,
such as ha of po assium on digi alis glycosides or
calcium on calcium-en ry blockers, and useful an-
agonis effec s, such as ha be ween a poison and
an an ido e, are also no included. Mos in erac-
ions of drugs wi h foods, beverages or o her nu ri-
en s are no lis ed, bu foods in erac ing wi h
monoamine oxidase inhibi ors are included.
MECHANISMS OF INTERACTIONS —
Gene ic differences can affec drug me abolism
and in erac ions. Some drugs can in erac by
changing he me abolism of o her drugs, ei her
hrough inhibi ion or induc ion of any of several
hepa ic enzyme ac ivi ies or hrough al era ions in
hepa ic blood flow. Many drugs are me abolized
by cy ochrome P450 isozymes. A reference able