Human Design Medical Z1 Auto System User manual

AN AFFILIATE OF BREAS MEDICAL AB
Human Design Medical, LLC
Z1 Auto™System
AUTO-ADJUSTING CONTINUOUS POSITIVE AIRWAY PRESSURE SYSTEM
User Guide
User Guide
English
AN AFFILIATE OF BREAS MEDICAL AB
Human Design Medical, LLC
Charlottesville, VA 22902
Z1 Auto User Guide v1 11102014
#40-0028 Rev. A
www.TheCPAPShop. com
866-414-9700

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Contents
Welcome to Your Z1 Auto System ..............................................................2
Owner/User Responsibility ...................................................................2
Healthcare Provider Responsibility............................................................2
Replacement Parts and Supplies .............................................................2
Terms Used in this User Guide ................................................................3
Medical Information ...........................................................................3
Z1 Warnings and Cautions .....................................................................4
Battery Warnings and Cautions .................................................................7
Getting to Know Your Z1 Auto System..........................................................8
Package Contents............................................................................8
Z1 Auto CPAP Device.........................................................................9
Power Supply (AC to DC Power Adapter) .....................................................9
Tube Adapter ................................................................................9
CPAP Tube ...................................................................................9
End Cap. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
Filter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
USB Micro Cable .............................................................................9
PowerShell (Optional Accessory) .............................................................9
Initial Set Up ..................................................................................10
Unpacking the Z1 Auto Box .................................................................10
Assembling and Powering Up ...............................................................11
Using Your Z1 Auto ...........................................................................13
LCD Display .................................................................................13
Function Modes.............................................................................14
Starting and Stopping Treatment............................................................15
Choosing Between Z-Breathe Settings.......................................................15
Programming Ramp Mode .....................................................…………….16
Z1 Auto Bluetooth Connectivity .............................................................17
Z1 Auto NiteLog Bluetooth App .............................................................17
Z1 User Software............................................................................17
Charging the Battery (PowerShell Only)......................................................17
Care ..........................................................................................18
Inspections .................................................................................18
Cleaning ...................................................................................18
Reminder Alert (Air Leak Detection) ...........................................................19
Fault Conditions ..............................................................................20
USB Firmware Upgrade. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20
Troubleshooting ..............................................................................20
Guidance and Manufacturer’s Declaration .....................................................22
Technical Specifications .......................................................................26
Servicing......................................................................................28
Limited Warranty..............................................................................28
Contact Information ..........................................................................28
FAA Compliance ..............................................................................29
Product Registration ..........................................................................31
Z1 Auto™, Z1 Unplugged™, and NiteLog™ are trademarks of Human Design Medical, LLC. The HDM logo ( ), Z1®,
PowerShell® and Z-Breathe® are registered trademarks of Human Design Medical, LLC. Breas is a registered trademark
of Breas Medical AB. All other trademarks are the property of their respective owners.
Patent Pending. © Copyright 2014, Human Design Medical, LLC. All rights reserved.
Printed in the USA.

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Welcome to Your Z1 Auto System
Thank you for choosing the Z1 Auto System from Human Design Medical– designed and
engineered in the USA with you in mind.
The Z1 is specially designed with these features:
• Z-Breathe®–theZ1 automatically reduces the air pressure in the mask to relieve
pressure when you exhale and to level out the pressure differences in your natural
breathing pattern.
• LeakCompensation–theZ1 automatically compensates for minor air leakage
helping ensure the proper treatment pressure is maintained.
• AutoAltitudeAdjustment–theZ1adjuststoaltitudesupto8000ftabovesealevel.
• AirTravel–TheZ1adjuststoanairplane’scabinpressureandisapprovedforuseon
airplanes.
• UpgradableOperatingSystem–theZ1 firmware and software can be easily updated
via the USB Cable and your computer.
This User Guide will help you take advantage of the features and capabilities of this amazing
portable,auto-adjustingCPAPdevice.PleasereadthisUserGuidecarefullybeforeusingyourZ1.
Owner/User Responsibility
The owner/user of the Z1 Auto System is responsible for reading and understanding this User
Guide.Theuserisresponsibleforanyinjuryordamagethatresultsfrom:
• OperationoftheZ1 other than in accordance with the operating instructions
contained in the User Guide supplied.
• Unauthorizedmaintenanceormodicationstothedeviceorattachedaccessories.
Healthcare Provider Responsibility
Your healthcare provider is responsible for explaining contraindications and instructions for use to
the patients/users.
Replacement Parts and Supplies
Use only genuine Z1 replacement filters, parts and supplies. Replacement filters, parts and
supplies can be purchased from Human Design Medical at 1-855-436-8724 [1-855-HDMUSA4]
or online at www.hdmusa.com. Use of unauthorized filters, parts or replacement supplies can
damage the device and void the warranty.

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Terms Used in this User Guide
This User Guide contains special terms and icons that appear in the text to draw your attention to
specific and important information.
WARNINGalertsyoutopossibleinjuryorhazard.
CAUTION explains special measures for the safe and effective use of the
device.
NOTE is an informative or helpful note.
Medical Information
Indications for Use
Your Z1 Auto System is a single patient, reusable device that provides continuous positive airway
pressure (CPAP) to support treatment of adults weighing over 66 lbs (30 kg) with obstructive sleep
apnea (OSA).
Contraindications
Positive airway pressure therapy may be contraindicated in some individuals with the following
pre-existing conditions:
• Severebullouslungdisease
• Pneumothorax
• Pathologicallylowbloodpressure
• Dehydration
• Cerebrospinaluidleak,recentcranialsurgery,ortrauma.
Adverse Effects
Users should report unusual chest pain, severe headache, or increased breathlessness to
their prescribing physician. An acute upper respiratory tract infection may require temporary
discontinuation of treatment.
The following side effects may arise during the course of therapy with CPAP devices:
• Dryingofthenose,mouth,orthroat
• Eyeirritation
• Nosebleed
• Bloating
• Skinrashes
• Earorsinusdiscomfort.

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Z1 Warnings and Cautions
WARNINGS:
• ReadtheentireUserGuidebeforeusingyourZ1. Consult your healthcare provider if
there is any part of this User Guide you do not understand.
• USFederallawrestrictsthisdevicetosalebyorontheorderofaphysician.
• UseyourZ1 and its accessories only for their intended use as described in this User
Guide and as directed by your physician, clinician or healthcare provider.
• TheZ1 is not approved for use with oxygen. Do not use supplemental oxygen or
any other type of supplementary gas with your Z1. Do not connect supplementary
oxygen or other gas to any accessory or patient interface which is connected to your
Z1.
• IfyounoticeanyunexplainedchangesintheperformanceofyourZ1 or your Z1
is making unusual or harsh sounds, or if the Z1 or Power Supply are dropped or
mishandled, discontinue use and contact the Human Design Medical Service Center
at 1-855-436-8729 [1-855-HDMUSA9].
• IfyourZ1, Power Supply, PowerShell or Battery is dropped or mishandled, or if water is
spilled into an enclosure, or if an enclosure is broken, discontinue use and contact the
Human Design Medical Service Center at 1-855-436-8729 [1-855-HDMUSA9].
• Amaskisnotprovided.YourZ1 should only be used with masks and connectors
recommended by your physician, clinician, respiratory therapist or healthcare
provider.
• YourZ1 is intended to be used with CPAP masks (or connectors) which have vent
holestoallowcontinuousowofairoutofthemask.WhenyourZ1 is turned on
and functioning properly, new air from the Z1ushestheexhaledairoutthrough
the mask vent holes. However, when the Z1 is not operating properly (e.g., at low
pressure) or the Z1 is off, insufficient fresh air may be provided through the mask and
the exhaled air may be rebreathed. Rebreathing exhaled air for longer than several
minutes can, in some circumstances, lead to suffocation. This applies to most CPAP
devices. Your healthcare provider will recommend a mask and air tubing to suit
your needs. The Z1 supports several CPAP mask types including nasal masks, full face
masks, and nasal prongs that meet the ISO 17510-2 standard.
• DonotuseyourZ1 with a mask unless the Z1 is turned on. Once the mask is fitted,
conrmthatairisowingfromyourZ1.
• Donotblocktheventholeorholesinthemask.Followthemaskmanufacturer’s
instructions for proper use of the mask.
• Intheeventofapowerfailureormachinemalfunction,removethemask
immediately.
• Atlowpressuressomeexhaledgasesmayremaininthemask.
• Electrocution Hazard – Your Z1 is an electrical device, and as such, you should not
immerse your Z1, Power Supply, PowerShell or Battery in water. Always unplug your

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Z1 and its accessories before cleaning (and clean only as instructed in this User Guide)
and make sure your Z1 and its accessories are dry before plugging back in.
• Beforeuse,makesurethepowercordandplugareingoodconditionandthatthe
cord is not damaged.
• Donotusebleach,chlorine,alcohol,oraromatic-basedsolutions,moisturizingor
antibacterial soaps or scented oils to clean your Z1, Power Supply, PowerShell or
Battery. These solutions may create a shock hazard, cause damage and reduce the life
of these items.
• Explosion Hazard — Do not use or store your Z1, Power Supply, PowerShell or
Batteryinthevicinityofammableanestheticsoroxygen.
• DonotuseyourZ1 near toxic or harmful vapors.
• DonotdropyourZ1 or any of its accessories or expose it to any crushing forces.
Should your Z1 be dropped and fail to operate properly, contact the Human Design
Medical Service Center at 1-855-436-8729 [1-855-HDMUSA9] before using the Z1 for
treatment.
• DonotinsertanyobjectintoanytubingoropeningofyourZ1 except as described in
this User Guide.
• DonotoperateyourZ1 in any area which may block its air intake. Blocking the CPAP
Tube and/or air inlet of your Z1 while in operation could lead to overheating of the Z1.
• IfyouputtheZ1ontheoor,makesuretheareaisfreefromdustandclearof
bedding,clothesorotherobjectsthatcouldblocktheairinletorcoverthePower
Supply unit.
• OnlystoreortransporttheZ1 and accessories within the storage and transport
temperature, humidity and altitude conditions specified in the Technical
Specifications section of this User Guide.
• DonotoperateyourZ1, Power Supply, PowerShell or Battery in an area which may
cause overheating.
• DonotcoverthePower Supply, PowerShell or Batterywithanyobjectormaterial
which would cause them to overheat.
• Keepthepowercord,Power Supply, Battery and Z1awayfromhotorammable
surfaces, gases or materials.
• DonotopenyourZ1 or tamper with its accessories. There are no user serviceable
parts inside. Repairs and servicing should only be performed by an authorized Human
Design Medical service agent.
• OnlypowertheZ1 with the Human Design Medical Power Supply (AC-to-DC power
adapter, HD60-6010) or the optional Human Design Medical PowerShell with Human
Design Medical Battery. Do not use any other AC adapters, batteries, or other power
sources to power the Z1. Do not use the Human Design Medical Power Supply,
PowerShell or Battery to power any device other than the Z1.

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• YourZ1 should only be used with standard or slim style CPAP air tubing as
recommended by your physician, clinician or healthcare provider.
• Donotleavelonglengthsofairtubingaroundthetopofyourbed.Thetubecould
twist around your head or neck while you are sleeping.
• Donotconnectorinsertanydevice,cableorarticlesintotheMicroUSBorMicroSD
ports of your Z1 except as described in this User Guide. Connecting other devices
couldresultininjurytoyouordamagetotheZ1 and void the warranty.
• DonotlocateyourZ1 in an unapproved place or where the air intake can be blocked
during treatment. This will lead to overheating of the Z1. If a blocked intake should
occur during operation, the unit may stop supplying pressurized air and cause a fault
condition. Refer to“Troubleshooting”in this User Guide to interpret this fault and
instructions for corrective action.
• TheZ1 is designed to deliver pressures from 4 to 20 cm H2O. In the unlikely event of
certain fault conditions, pressures of up to 30 cm H2O are possible.
• BlockingtheCPAP Tube while in operation could lead to overheating of the Z1.
• Intheclinicalenvironment,anypersonalcomputerthatisusedwithyourZ1 system
must be at least 5 feet (1.5 m) away from, or at least 8 feet (2.5 m) above, the patient.
It must also comply with the relevant test standard. For personal computers the
international standard is IEC 60950 or equivalent.
CAUTIONS:
• BecarefulnottoplaceyourZ1 where it can be bumped or where someone is likely to
trip over the power cord.
• MakesureyourZ1, Power Supply, PowerShell and Battery are kept clean, dry, and free
of dust.
• Alwaysmakesurethepowercordandplugsareingoodconditionandthe
equipment is not damaged before use.
• MakesuretheareaaroundyourZ1 and accessories is dry and clean.
• Duringpartial(belowratedminimumvoltage)ortotalpowerfailure,therapy
pressures will not be delivered. When power is restored, your Z1 will enter standby
mode and all prior settings will be retained in memory.
• FollowthestorageandcleaninginstructionsprovidedwithyourCPAP Tube and mask.
• TheairltershouldbechangedatintervalsspeciedinthisUserGuide.
Accumulation of filtered particles over time can reduce the efficiency and shorten the
life of any CPAP device, including the Z1. Replacement filters are available at 1-855-
436-8724 [1-855-HDMUSA4] or online at www.hdmusa.com.
• Donotwashtheairlter.Theairlterisnotwashableorreusable.
• TheEnd Cap protects the Z1 in the event of a minor collision. Always ensure that the
End Cap is securely fitted in accordance with instructions at all times. The Z1 may not
operate if the End Cap is not properly installed.

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• ThetemperatureoftheairowforbreathingproducedbyCPAPdevicescanbehigherthan
the temperature of the room. This is true of all CPAP devices. Caution should be exercised
when using your Z1 at room temperatures warmer than 90˚F (32˚C).
• OnlyoperatetheZ1 and accessories within the operating temperature, humidity and
altitude conditions specified in the Technical Specifications section of this User Guide.
• OnlystoreortransporttheZ1andaccessorieswithinthestorageandtransport
temperature, humidity and altitude conditions specified in the Technical Specifications
section of this User Guide.
• DamagetotheCPAP Tube may result in air leaks. If this occurs, stop using the damaged
CPAP Tube and replace immediately.
Battery Warnings and Cautions
The PowerShell comes with a removable Lithium Ion Battery. Careful attention must be paid to
the warnings and cautions described below relating to the Battery. Misusing the Battery may
cause the Batterytogethot,rupture,igniteandcauseseriousinjury.
WARNINGS:
• DonotplacetheBattery in fire or heat the Battery.
• DonotinstalltheBattery backwards so that the polarity is reversed.
• DonotconnectthepositiveterminalandthenegativeterminaloftheBattery to each other
withanymetalobject(suchaswire).
• DonotcarryorstoretheBatterytogetherwithnecklaces,hairpins,orothermetalobjects.
• DonotpiercetheBattery with nails, strike the Battery with a hammer, step on the Battery or
otherwisesubjectittostrongimpactsorshocks.
• DonotsolderontotheBattery.
• DonotexposetheBattery to water or salt water, or allow the Battery to get wet.
• DonotdisassembleormodifytheBattery. The Battery contains safety and protection
devices which, if damaged, may cause the Battery to generate heat, rupture or ignite.
• DonotplacetheBattery on or near fires, stoves or other high-temperature locations. Do not
place the Battery in direct sunlight, or use or store the Battery inside cars in hot weather.
Doing so may cause the Battery to generate heat, rupture or ignite. Using the Battery in this
manner may also result in a loss of performance and a shortened life expectancy.
• ImmediatelydiscontinueuseoftheBattery if, while using, charging or storing the Battery,
the Battery emits an unusual smell, feels hot, changes color, changes shape or appears
abnormal in any other way. Contact the Human Design Medical Service Center at 1-855-
436-8729 [1-855-HDMUSA9] if any of these problems are observed.
• DonotplacetheBattery in microwave ovens, high-pressure containers, or on induction
cookware.

8
• IntheeventthattheBatteryleaksandtheuidgetsintoone’seye,donotrubtheeye.Rinse
wellwithwaterandimmediatelyseekmedicalcare.Ifleftuntreatedthebatteryuidcould
cause damage to the eye.
• OnlychargetheBattery with the supplied Human Design Medical PowerShell and the
supplied Human Design Medical Power Supply. Do not use any other removeable battery
charger, AC adapter, or other device to charge the Battery.
• DonotattachtheBattery directly to a vehicle cigarette lighter or to the Power Supply plug.
• DonotcontinuechargingtheBattery if it does not recharge within the specified charging
time. Doing so may cause the Battery to become hot, rupture or ignite.
• RemovetheBattery from the PowerShell if the Z1 is not likely to be used for some time. Do
not use the Battery to power any device other than the Z1.
• OnlyuseorchargetheBattery within the operating temperature, humidity and altitude
conditions specified in the Technical Specifications section of this User Guide.
• OnlystoreortransporttheBattery within the storage and transport temperature and
humidity conditions specified in the Technical Specifications section of this User Guide.
CAUTION:
• WhentheBattery is worn out, insulate the terminals with adhesive tape or similar
materials before disposal.
Getting to Know Your Z1 Auto System
Package Contents
Z1 Auto Base Model
Z1 Auto CPAP Device
Power Supply & Cord
Custom USB A to Micro B Cable
Custom CPAP Tube Adapter
48” Slim Style CPAP Tube
End Cap
Filter (2- 1 installed in Z1, 1 in box)
Heat / Moisture Exchanger (HME)
Z1 Auto Getting Started Guide
Z1 Auto User Guide
PowerShell Module
Overnight Battery
Battery Shuttle
PowerShell
PowerShell Getting Started Guide
The Z1 Auto Unplugged contains both the Z1 Auto Base Model and the PowerShell Module.

9
Z1 Auto CPAP Device
The Z1 supplies continuous positive airway pressure and can be programmed to fit the patient’s
prescriptive needs.
Power Supply (AC to DC Power Adapter)
The Power Supply provides power to the Z1. It takes AC power (voltage ranging from 100-240
volts) from a wall outlet and converts it to DC voltage to power the Z1. The Power Supply can be
used with international power sources provided the appropriate plug adapter is used.
Tube Adapter
The Tube Adapter attaches the CPAP Tube to the Z1.
CPAP Tube
The Z1 System is provided with a 4 ft slim style CPAP Tube. The CPAP Tube connects the Z1 to your
mask. Always consult with your physician or healthcare provider regarding the selection of tubing
for your treatment. Follow the instructions provided with the tubing. Replacement tubing can be
purchased from Human Design Medical at 1-855-436-8724 [1-855-HDMUSA4] or online at www.
hdmusa.com.
End Cap
The End Cap attaches to the air intake end of the Z1 and houses the Filter.
Filter
The Z1 uses a specially designed filter. The material has been specifically chosen for the Z1 and
has been designed to be much larger than other CPAP filters. The unique shape of the lter fits
into the End Cap of the Z1, which was designed to allow for more effective filter surface area.
For proper operation of the Z1, the Filter should be replaced monthly or more often if necessary.
USB Micro Cable
The USB Cable allows the Z1 to communicate with a computer to collect and view user data.
PowerShell (Optional Accessory)
The PowerShell houses both the Z1 and the Battery which allows temporary usage of the Z1
without the Power Supply. It can be purchased at 1-855-436-8724 [1-855-HDMUSA4] or online at
www.hdmusa.com.
NOTE: Replacement parts, supplies and accessories can be purchased from
Human Design Medical at 1-855-436-8724 [1-855-HDMUSA4] or online at
www.hdmusa.com.

10
Initial Set Up
Unpacking the Z1 Auto Box
You will need to perform a few minor setup steps before using your new Z1. The instructions
below will guide you through the setup process. Some of the steps outlined below may have
been performed by your healthcare provider prior to delivering the Z1 to you. If you have any
questions or problems as you go through the setup process, please call Human Design Medical
Customer Service at 1-855-436-8729 [1-855-HDMUSA9] for assistance. Human Design Medical
wants your user experience with the Z1 to be trouble and frustration free.
1. Carefully remove the contents of the box.
2. Some of the Z1 components have their own packaging material. Remove this material
carefully. Avoid using anything sharp when opening the packaging.
3. Carefully inspect all contents against the package contents list on page 8 to assure
all components are present. Keep in mind that your healthcare provider might have
completed some of the setup steps prior to delivery, so if a component appears to
be missing, check to see if it has already been connected. Also inspect all contents
to ensure there is no obvious or visible damage or defects. If you have any concerns
or questions, contact Human Design Medical Customer Service at 1-855-436-8729
[1-855-HDMUSA9], or your service or healthcare provider before use.
4. Place all the components in an area where you can easily access the Z1 for set up and
programming.
WARNING: Do not use this product if you have any concerns about the
condition of the contents or if there are any missing parts.
The contents of the Z1 box includes the following:
Z1 Auto System
Z1 Auto
Filter
Slim-style
CPAP tube
AC DC Adapter
Power Cord
Tube Adapter
USB Cable

11
Z1 Auto Unplugged
Includes everything that comes with the Z1 Auto Base Model, plus:
Assembling and Powering Up
Filter and End Cap
Your Z1 comes with the first filter already installed. Replacement
filters may be installed as follows:
1. Remove the End Cap from the Z1.
NOTE: To remove the End Cap, squeeze
firmly on the sides of the End Cap and pull it
away from the Z1.
2. Pull used Filter out of the End Cap.
3. Remove new Filter from its packaging.
4. Insert the new Filter into the End Cap, aligning the arched
side of the Filter with the top of the End Cap. Ensure
the Filter covers all holes in the End Cap, so that all air
entering the Z1 passes through the Filter and no air
bypasses the Filter.
5. Press the End Cap onto the Z1. (Figure 1)
Tube Adapter, CPAP Tube and Mask
1. Connect one end of the CPAP Tube to the round end of
the Tube Adapter then insert the other end of the Tube
Adapter into the outlet of the Z1. (Figure 2)
2. Connect the other end of the CPAP Tube to the mask.
3. Ensure all connections are tight to avoid air leaks.
(Figure 3)
Figure 1
Battery Shuttle and
Overnight Battery
PowerShell
Figure 2
Figure 3

12
Figure 6
Figure 7
Figure 8
Figure 4
Figure 5
Power Supply
WARNING: The Z1 must only be used with
the Human Design Medical Power Supply
(or the optional Human Design Medical
PowerShell with Human Design Medical
Battery). DO NOT use any other power source
with the Z1.
CAUTION: Make sure the AC power cord
IS NOT plugged into an AC power outlet
before continuing to the next step.
1. Plug the AC power cord into the AC Adapter.
2. Plug the AC power cord into a wall outlet.
3. Plug the AC Adapter into the Z1. (Figure 4)
4. The Z1 will power up and cycle through a series of
startup displays.
5. After about 10 seconds, the Z1 will enter standby mode.
The display will read 0.0. (Figure 5)
NOTE: The Z1 display will be active whenever
the device is receiving power.
PowerShell and Battery (Available Separately)
WARNING: The Z1 must only be used
with the optional Human Design Medical
PowerShell with Human Design Medical
Battery (or the Human Design Medical Power
Supply). DO NOT use any other power source
with the Z1.
1. Slide the Battery with the attached Shuttle into the lower
bay of the PowerShell until the Shuttle clicks into place.
(Figure 6)
NOTE: The Battery can be removed from the
PowerShell by pressing the two blue buttons
on the Battery Shuttle and sliding the Battery
out.
2. Slide the Z1 all the way into the upper bay of the
PowerShell until you hear a “click” sound, indicating the Z1
has locked into place. (Figure 7)
CAUTION: Insert the Z1 carefully ensuring
the power barrel connector slides into the
power input on the Z1.

13
NOTE: The Z1 can be removed from the PowerShell by pressing the two
[ ] symbols on the sides of the PowerShell and sliding the Z1 out.
3. The Z1 will power up and cycle through a series of startup displays.
4. After about 10 seconds, the Z1 will enter standby mode. The display will read 0.0.
(Figure 8)
NOTE: Remove the Battery from the PowerShell when the Z1 is not in
use, unless the Power Supply is plugged into the PowerShell to charge the
Battery. Otherwise the Z1 and PowerShell will drain the battery completely
within 2-3 days.
Using Your Z1 Auto
LCD Display
Treatment Pressure Display
The current treatment pressure is shown on the LCD display. Once set, the prescribed treatment
pressure will be retained in the Z1’s memory even during loss of power. For example, a treatment
pressure setting of 10.0 cm H2O is displayed in Figure 9.
Ramp Progress & Ramp Time Remaining Indicators
Ramp Mode allows you to gradually acclimate to the prescribed treatment pressure. Ramp Mode
gradually increases the pressure from a low initial starting pressure to the prescribed treatment
pressure over a programmed interval of time. See “Programming Ramp Mode”.
If you program the Z1 for Ramp Mode, the Ramp Progress and Ramp Time Remaining indicators
willappearontheLCDdisplay.Forexample,Figure9indicatesthattherampisjustoverhalf
complete, with a ramp time remaining of 10 minutes.
Battery Status Display
This icon is displayed when the optional PowerShell and Battery are connected. The level of
charge remaining on the Battery is indicated by the number of solid bars in the icon. The bars
ashwhentheBattery is charging. For example, the icon shown in Figure 9 indicates that the
Battery has between 25-50% of charge remaining. Make sure the Battery is fully charged before
each use.
Treatment Pressure
Display
Ramp Progress
Ramp Time
Remaining
AC Power Indicator
Battery Status Display (PowerShell Only)General Status Display
Fault
Reminder
Figure 9

14
FAULT
“FAULT” is displayed if one of several conditions has occurred that require your attention. See Fault
Conditions (page 19) for explanations of the FAULT codes.
REMINDER
“REMINDER” is displayed if there is excessive air leakage. See Reminder Alert (page 19) for an
explanation of REMINDER conditions.
Function Modes
The following modes can be selected for the Z1:
– CPAP mode (Continuous Positive Airway Pressure)
–APAPmode(self-adjustingintelligentCPAPmode)
NOTE: Function Modes can ONLY be set by a healthcare provider.
During active treatment, the Function Mode is displayed in the General Status Display field.
Number of Solid Bars Charge Remaining
1 10-25%
2 25-50%
3 50-75%
4 75-100%
AC Power Indicator
This icon is displayed when the Z1 is connected to an AC power outlet via the Power Supply.
General Status Display
In Standby mode, this display field alternates between a display of the current date, the current
function mode and Z-Breathe setting and the current Bluetooth status (Bluetooth on or Bluetooth
off ). During treatment and while setting treatment parameters, this display field shows the
currently selected function mode (APAP or CPAP) and Z-breathe setting (1, 2 or 3).
The General Status Display field may also give notification of certain events which will NOT
prevent the Z1 from operating normally but may need to be addressed by the user.
Code Event Resolution
Fail 1 Attempt to restart while motor is still running Wait at least 10 seconds
before attempting to restart
treatment again.
Fail 2 Attempt to set ramp start pressure while ramp time = 0 Set ramp time to a minimum
of 5 minutes to enable the
ability to set ramp start pres-
sure.
Fail 3 Attempt to save treatment pressure while device is locked Treatment pressure changes
can only be made by a trained
healthcare provider while the
device is unlocked.

15
Current
Treatment
Pressure
Start/Stop
Button
Figure 10
PRESSURE
cmH20
MINUTES
Z-Breathe Setting
Mode
PRESSURE
cmH20
MINUTES
Z-Breathe Setting
Mode
Figure 11
Figure 12
Starting and Stopping Treatment
1. Press the Start/Stop Button on the Z1 to initiate
treatment using the pre-programmed prescription
setting. The Treatment Pressure Display will show the
actual pressure being delivered at all times. If the Ramp
Mode has been programmed, the ramp start pressure
will be displayed upon pressing the Start/Stop Button
and the indicated pressure will rise as the Z1 ramps up
to the prescribed treatment pressure. If the incorrect
pressure is displayed, contact your healthcare provider
before commencing treatment. (Figure 10)
CAUTION (When using the PowerShell
Only): Make sure your Battery is fully charged
before commencing treatment using the
PowerShell. The battery life of a fully charged
battery in the PowerShell is typically 8 hours
or longer and treatment will terminate when
the charge is expended. To recharge the
Battery, see “Charging the Battery”.
2. Press the Start/Stop Button a second time to stop
treatment.
Choosing Between Z-Breathe™settings
The Function Mode Setting is shown in the General Status Display
field on the LCD. APAP mode is designated by the word “APAP” and
CPAP is designated by the word “CPAP”.
NOTE: Function Modes can ONLY be set by a
healthcare provider.
The Z-Breathe setting of 1-3 is indicated by the number following
the APAP or CPAP designation on the LCD screen. For example,
APAP-2 means APAP mode with Z-Breathe setting of 2 (Figure 11)
and CPAP-3 means the CPAP mode with a Z-Breathe setting of 3.
(Figure 12) To set the Z-Breathe setting, press and hold down the
Up Arrow Button and Down Arrow Button simultaneously while
in the Standby mode (pressure of “0.0” indicated on the display).
OnceyouseetheFunctionModeindicatorashingontheLCDscreen,youcanselectthedesired
Z-Breathe setting using the Up Arrow Button and Down Arrow Button. After you have made your
selection, press and hold the Start/Stop Button to save it.
Your selected setting for the Z-Breathe Algorithm will be retained in the memory of your Z1 unit
after it is turned off. The currently selected Z-Breathe Algorithm setting will be displayed when
the Z1 is delivering treatment pressure.
Z-Breathe is a proprietary algorithm engineered in the Z1 to smooth out the breathing cycle
whileenjoyingthebenetsofCPAPtreatment.Typicallyusersexperiencepressureswingswhile
breathing on a CPAP device. Pressure swings occur as a spike in pressure during exhalation and
a drop in pressure during inhalation. Z-Breathe is designed to minimize the impact of spikes and

16
Setting Ramp Time
When the Z1 is in standby mode, press and
hold the Up Arrow Button for approximately 3
secondsuntilthe“00MINUTES”valueashes.
Whileitisashing,repeatedlypresseither
the Up or Down Arrow Buttons to increase
or decrease the ramp time in 5 minute
increments. (Figure 13) Set the ramp time to
“00 MINUTES”to disable the Ramp Mode.
When the desired ramp time value is reached,
press and hold the Start/Stop Button for
approximately 3 seconds to save your ramp
time setting (this setting will be saved even
when
the Z1 is not powered). The Z1 will return
to standby mode. To return to standby mode
Up
Arrow
Button
Down
Arrow
Button
Ramp
Time
Ramp
Pressure
Figure 13
drops while keeping the pressure constant, thereby delivering more comfortable therapy.
Pressure swings can vary between users due to lung capacity and other factors. For this reason we
have created 3 levels of Z- Breathe to accomodate individual users’ preferences:
— 1offers mild pressure swing relief
— 2is the Default Setting and offers moderate pressure swing relief
— 3is the most aggressive setting for pressure swing relief
Programming Ramp Mode
Some users find it comforting to acclimate to treatment each session. This can be accomplished
by programming the Ramp Mode which allows you to start with a lower initial pressure and
gradually increase to the prescribed treatment pressure.
without saving the new setting, press and release the Start/Stop Button momentarily instead of
holding it down.
NOTE: Ramp Time must be set to a minimum of 5 minutes prior to
attempting to program Ramp Start Pressure or the change to Ramp Start
Pressure will not take effect and “FAIL 2” will be shown in the General Status
Display field.
Setting Ramp Start Pressure
Press and hold the Down Arrow Buttonfor3secondsuntiltherampstartpressurevalueashes.
Whileashing,repeatedlypresseithertheUp or Down Arrow Buttons to increase or decrease the
ramp start pressure by 0.5 cm H2O increment. (Figure 13) Ramp start pressure must be lower than
prescribed pressure.
When the desired value for ramp start pressure is reached, hold down the Start/Stop Button for
approximately 3 seconds to save your setting. The Z1 will return to standby mode. To return to
standby mode without saving the new setting, press the Start/Stop Button momentarily instead
of holding it down.

17
Human Design Medical provides User Software for data viewing
which may be downloaded from the Human Design Medical
website to any Windows computer. A separate user guide for
this software is available for download at the Human Design
Medical website, www.hdmusa.com. This software can be used to
upgrade the Z1 firmware as new releases are made available.
Charging the Battery (PowerShell Only)
WARNING: Only charge the Battery with the
supplied Human Design Medical PowerShell and the
supplied Human Design Medical Power Supply. Do
not use any other battery charger, AC adapter, or other
device to charge the Battery.
With both the Z1 and the Battery fully inserted into the
PowerShell, plug the Power Supply into the PowerShell as shown
and into a power outlet. (Figure 16)
CAUTION: Make sure your Battery is fully charged
before commencing therapy using the PowerShell. The
battery life of a fully charged battery in the PowerShell
is typically 8 hours or longer, after which treatment will
terminate.
Z1 Auto Bluetooth Connectivity
In order for the Z1 to connect to the Z1 NiteLog™Mobile
App, the Z1’s Bluetooth must be turned on. Once the Z1 has
connected to the NiteLog App via Bluetooth, access between
the NiteLog App and Z1 device is password protected. If the
password is incorrect the Mobile App will be denied access to
the Z1 device.
Immediately after plugging the Power Adapter into your Z1,
hold the Up Arrow Button. “bt-On” will display on the screen to
indicate your Bluetooth has been turned on. (Figure 14)
To turn off the Bluetooth capability on your Z1 (Airplane
Mode), unplug the Power Adapter from your Z1. Plug your
Power Adapter back into your Z1 and immediately hold down
the Down Arrow Button.“bt-Off”will display on the screen to
indicate your Bluetooth has been turned off. (Figure 15)
Figure 16
Figure 17
PRESSURE
cmH20
PRESSURE
cmH20
Figure 14
Figure 15
Z1 Auto NiteLog™Bluetooth App
Your Z1 Auto has a range of functionality from device remote control to data viewing available via
its embedded Bluetooth capability. The Z1 Nitelog™App is available for download at the iTunes
App Store™. A separate Z1 Nitelog™App User Guide is available for download on the Human
Design Medical web site, www.hdmusa.com. This App User Guide provides an overview of the
App as well as detailed use instructions.
Z1 User Software

18
Ensure the Z1 is in standby mode (display reads 0.0). The Battery will not charge unless the Z1 is in
standby mode. The Battery status indicator on the Z1willashwhentheBattery is charging. The
number of solid bars indicates the current level of charge. (Figure 17)
Thebatterystatusindicatorwillstopashingwhenthebatteryisfullycharged.Typicallyitwill
take 8 hours to fully charge the battery. After a few minutes, the backlit display will turn off. This is
to conserve power. It does not indicate that the battery is fully charged.
NOTE: The battery will not charge if you are using your Z1 Auto at the same time.
Care
The Z1 Auto System needs periodic care. It is the user’s responsibility to be aware of the following
items for care:
• Inspections
• Cleaning
• Filter Replacement
• CPAP Tube Replacement
• RemindersandFaultConditions
Inspections
Before each use carefully inspect the Z1, CPAP Tube, Filter, and mask for signs of wear, damage
or discoloration. Contact Human Design Medical for replacement parts at 1-855-436-8724
[1-855-HDMUSA4] or online at www.hdmusa.com.
Cleaning
Regular cleaning should be performed in accordance with the instructions below.
WARNING: This device can expose you to electrocution. Do not
immerse the Z1, Power Adapter, Power Cord or Battery in water. Always
unplug these devices before cleaning (only as instructed in this User Guide)
and make sure they are dry before plugging back in.
CAUTION: Do not use bleach, chlorine, alcohol, or aromatic-based
solutions, moisturizing or antibacterial soaps or scented oils to clean the
Z1. Never attempt to clean the Power Adapter, PowerShell, Battery or
accessories with any of these solutions. These solutions may create a shock
hazard, cause damage and reduce the life of these products.
Daily
1. Remove the CPAP Tube and the mask from the Z1.
2. Wash the CPAP Tube in warm water using mild detergent.
3. Rinse thoroughly, hang, and allow to dry.
4. Before next use, reconnect the CPAP Tube and the Tube Adapter to the Z1 and mask.
NOTE: Soaking the CPAP Tube in water for longer than 10 minutes may
shorten the life of the tube.

19
Every 90 days
The CPAP tube should be replaced every 90 days or earlier if it becomes discolored, cracked or
damaged.
CAUTION: Do not use bleach, chlorine, alcohol, or aromatic-based
solutions, moisturizing or antibacterial soaps or scented oils to clean
the CPAP tube. Never attempt to clean the CPAP tube with any of these
solutions. These solutions may create a shock hazard, cause damage and
reduce the life of the CPAP tube.
CAUTION: Prolonged exposure to sunlight may cause the CPAP Tube to
discolor and degrade.
As Needed
1. Clean the exterior of the Z1 with a soft damp cloth and mild detergent and wipe
clean. Never submerge the Z1 in water. Do not allow soap or water to enter the Z1.
NOTE: Replacement CPAP tubes may be purchased directly from Human
Design Medical at 1-855-436-8724 [1-855-HDMUSA4] or online at
www.hdmusa.com.
Filter Replacement
The Filter should be inspected weekly for holes and blockage by dirt and dust, and should be
replaced every month (or more often if necessary). The Filter is accessed by removing the End Cap
as described in “Assembling and Powering Up: Filter and End Cap”.
NOTE: The Z1 uses a specially designed Filter that may be purchased
directly from Human Design Medical at 1-855-436-8724 [1-855-HDMUSA4]
or online at www.hdmusa.com.
WARNING: Do not attempt to use any air filter which is not supplied
by Human Design Medical for the Z1. The Z1 is designed to only work with
approved materials. A filter which is not approved may cause damage to
the Z1 from overheating.
CAUTION: Do not operate the Z1 without the Filter. The Z1 must
operate with a filter installed; failure to do so may damage the Z1 and allow
impurities into the respiratory system.
Reminder Alert (Air Leak Detection)
“REMINDER” is displayed on the LCD screen to indicate an excessive air leak. This could be because
you are not wearing your mask. Placing the mask on your face should remove REMINDER from the
display. If you are wearing the mask and REMINDER is displayed check the following connections
for air leaks:
• Tube Adapter to Z1
• CPAP Tube to Tube Adapter
• CPAP Tube to mask
• Masktoface(adjustpositionofmaskandheadgeartoeliminatetheairleak)