LaboGene CoolSafe User manual

Item No. 701157
CopyRight © 2016
INSTRUCTION MANUAL
CoolSafe
Control and Datalogger Software

Instruction manual for CoolSafe
01032016QA01
Item No. 701157
CopyRight © 2016
Page 2of 25
Symbols used in this manual

Note
Used to direct attention to a special item.
This document is the original instruction manual in accordance with the current Machinery Directive.
This document is the reference for any translation of this instruction manual. In case of doubts or
uncertainties the text in the original instruction manual is the valid.
LaboGene ApS
Industrivej 6-8
Vassingerød
DK-3540 Lynge
Denmark
Phone No. [phone]
Fax No. [phone]
Mail [email protected]
Internet www.labogene.com

Instruction manual for CoolSafe
01032016QA01
Item No. 701157
CopyRight © 2016
Page 3of 25
Table of contents
1Introduction..............................................................................................4
2Installation and setup of the software...................................................4
2.1 Loading the SD card..................................................................................4
2.2 Connecting to the CoolSafe.......................................................................9
3Using the control software ...................................................................13
3.1 Running an automatic freeze drying process ..........................................14
3.2 Running a manual freeze drying process................................................17
3.3 Running release.......................................................................................19
3.4 Running de-ice.........................................................................................19
4Datalogging, data managing and viewing...........................................20
4.1 General....................................................................................................20
4.2 Menu –Files ............................................................................................21
4.3 Menu - Show............................................................................................21
4.4 Menu - Functions.....................................................................................21
4.5 Menu –Data from controller....................................................................22
4.6 Menu - Settings........................................................................................22
5Annex –Software license agreement..................................................24
6Annex - Pressure of Aqueous Vapor...................................................25

Item No. 701157
CopyRight © 2016
1 Introduction
With every CoolSafe Touch, a dedicated software package is delivered without charge. The
CoolSafe Control and Datalogger software facilitates:
Full control of the CoolSafe freeze dryer from an external computer via a USB connection
Complete real-time monitoring and logging of temperature and pressure data from the freeze
drying process running
Viewing and converting data from previous runs.
This manual covers instruction on installing the software and connecting to the CoolSafe freeze
dryer, controlling and running the CoolSafe freeze dryer and logging and handling of the data from
the freeze drying process.
2 Installation and setup of the software
The CoolSafe Control and Datalogger software is delivered on the SD card placed in the SD card
reader located in the back panel of the CoolSafe cabinet.
Remove the SD card and load it into the computer you wish to install the software package on.
On the SD card a single self-extracting installation file is located. By running this file, the CoolSafe
Control and Datalogger software and the needed USB drivers for communication between the
computer and the CoolSafe unit. This software will run on windows based computers running 32 bit
or 64 bit Windows 7 or newer operating systems.
The installation can be run directly from the SD card or from any other media connected to the
computer.
2.1 Loading the SD card
When loading the SD card, Windows will need some time to install the drivers for handling this. This
takes a few moments and will be performed automatically.
Open the SD card and double click the installation file on the SD card.

Instruction manual for CoolSafe
01032016QA01
Item No. 701157
CopyRight © 2016
Page 5of 25
The installation process will begin. The installation is run by the wizard shown below. Simply follow
the wizard through the installation of the software.
In this window press next to continue.

Instruction manual for CoolSafe
01032016QA01
Item No. 701157
CopyRight © 2016
Page 6of 25
Read the License Agreement and remember to accept the terms hereof and press next.
Fill in user name and organisation –must be filled –and press next.
It is recommended to use the destination folder suggested.

Instruction manual for CoolSafe
01032016QA01
Item No. 701157
CopyRight © 2016
Page 7of 25
Press next.
Press next to complete the installation of the software on the computer.
After completion open the destination folder in Windows Explorer. Two folders should be in the
destination folder:

Instruction manual for CoolSafe
01032016QA01
Item No. 701157
CopyRight © 2016
Page 8of 25
Open the folder Labogene_CoolSafe_Touch_Datalogger…. and open it. Locate the application file
and right click to create a shortcut and place it on the desktop.
Go to the desktop and right click the shortcut. Press the Advanced option and select the “Run as
administrator option. Press OK.

Instruction manual for CoolSafe
01032016QA01
Item No. 701157
CopyRight © 2016
Page 9of 25
Press OK and the installation is complete.
2.2 Connecting to the CoolSafe
Before starting to connect the CoolSafe and the computer, make sure the cable (mini USB for the
CoolSafe and standard USB for the computer) between the two is in place. The USB port on the
CoolSafe is located on the back of the cabinet. Any USB port on the computer will do the job.
With the cable in place, double-click the shortcut to start the software.
Two windows will be opened. In front the main screen for the control part of the software package
and hidden behind it the datalogging, data managing and viewing part of the software.
Mini USB
Mini USB

Instruction manual for CoolSafe
01032016QA01
Item No. 701157
CopyRight © 2016
Page 10 of 25
The first time it is run, Windows will search for and install the appropriate drivers for the USB device
(the CoolSafe).

Instruction manual for CoolSafe
01032016QA01
Item No. 701157
CopyRight © 2016
Page 11 of 25
If the computer is connected to the internet, the drivers will be found there. If not, Windows will ask
for the folder, where they can be found. Point at the driver folder in the installation folder.
The driver will be installed automatically. When done Windows will say so.
To connect to the CoolSafe the software needs to know which COM port is being used. Open the
Device Manager in the Windows control panel, locate and open the Ports option and the USB serial
port from the list (in this case COM3).
Open the Datalogger window by pressing the “Grafs/Config” button. Open the “Settings” menu and
enter the “Comport setup” option. Select the COM port and press “Save”
If another COM port is used at a later time this procedure must be repeated.
From the same menu enter the “General setup” option to select interface language (currently English
or Danish), CoolSafe model and path to datalogging files.

Instruction manual for CoolSafe
01032016QA01
Item No. 701157
CopyRight © 2016
Page 12 of 25
When done, press close.
To check that the communication between the CoolSafe and computer is working properly, press F4
or open the “Data from controller” menu and select the “Controller clock” option. The window shown
below will open.
Press the “Receive Clock” button. If the controller clock values appear the connection is up and
running correctly.
The final step is to press the “Connect” button which will open a “Save As” window. Here the name
of the file for data logged must be given.

Instruction manual for CoolSafe
01032016QA01
Item No. 701157
CopyRight © 2016
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Press “Save” and the configuration of the CoolSafe is transferred to the software, that is ready for
use now.
The main screen of the control software will show a diagram of the CoolSafe as it is actually
configured and equipped.
3 Using the control software
It is important to understand, that it is the controller on the main board of the CoolSafe that actually
runs the freeze dryer –not the control software. With the control software it is possible to change the
settings of all user related parameters and to define freeze drying processes in manual and
automatic running mode.
Any changes made in the control software will remain there and not have any effect on the CoolSafe
until it has been send to the controller on the CoolSafe main board. To send data to the “Send” button
in the “Commando”box in the lower left-hand corner of the screen.

Instruction manual for CoolSafe
01032016QA01
Item No. 701157
CopyRight © 2016
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Navigating the control software is done from the “Setpoints” box, where a dropdown list gives all
available options.
Choose the desired option and press “Send” for the choice to take effect.
Before starting any freeze drying process manual or automatic, it is recommended to make sure all
is stopped by sending the “Stop” command from the “Setpoints” menu.
3.1 Running an automatic freeze drying process
To run an automatic freeze drying process, send “Auto” from the “Setpoints” menu. This command
will open the Auto screen shown below.
In this window a complete freeze drying cycle can be defined and executed. Pre-freezing in 5 steps
can be defined, alarm pressure must be defined and the primary drying can be defined in 10 steps.

Instruction manual for CoolSafe
01032016QA01
Item No. 701157
CopyRight © 2016
Page 15 of 25
To enter values for the different steps, click on the appropriate screen area and the input boxes
below will be opened.
For each step enter the desired values and
press send to accept the given values.
When programming is done, the program can
be saved to disc by pressing the “Save” button
in the Commando box.

Instruction manual for CoolSafe
01032016QA01
Item No. 701157
CopyRight © 2016
Page 16 of 25
The automatic freeze drying cycle starts by waiting for the temperature to gets low enough to start
the freeze drying process.
When the correct temperature is reached the automatic freeze drying process will start and continue
until all pre-freezing (if available) and primary drying programme steps have been completed.

Instruction manual for CoolSafe
01032016QA01
Item No. 701157
CopyRight © 2016
Page 17 of 25
When the automatic freeze drying process is done it will be show in the status box. The freeze dryer
will continue cooling and keep the pressure at the latest set point.
Release and de-ice will have to be performed separately from the automatic freeze drying process.
3.2 Running a manual freeze drying process
Pressing the “Manual” button on the main screen will open the window shown below.
Click inside the freeze drying box and the setup box will appear. Same thing for the alarm pressure.
Enter the desired values and press send to upload the values to the CoolSafe control board.

Instruction manual for CoolSafe
01032016QA01
Item No. 701157
CopyRight © 2016
Page 18 of 25
Press the “Freeze Drying Stop” button to start the manual freeze drying process.
The freeze drying process will start and continue to run until the user stops it. Select the “Stop”
command in the dropdown list and press the “Send” button.

Instruction manual for CoolSafe
01032016QA01
Item No. 701157
CopyRight © 2016
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3.3 Running release
Choose the “Release” command from the dropdown list and press “Send” to start the release
process.
3.4 Running de-ice
Select the “De-ice” command from the dropdown list and press “Send”. The De-ice configuration box
will appear.
Enter the required de-ice time in hours and minutes and press “Send”. De-icing will start and run for
the specified time.

Instruction manual for CoolSafe
01032016QA01
Item No. 701157
CopyRight © 2016
Page 20 of 25
4 Datalogging, data managing and viewing
To view the datalogging press the “Grafs/Config” button on the main screen of the freeze dryer
control software.
4.1 General
In the Datalogger window, right click and the popup shown below appears.
Show graphs
Selection of what data will be
shown.
Zoom
Zooms in or out on the time axis
on the graph.
Show average
Opens window where average,
maximum and minimum values
for each parameter is shown.
One logging
-
Comments to data
Comment to data can be
added. Is shown on the printed
version of the data.