Metrohm 700 Dosino User manual

700 Dosino
Manual
8.700.1023

Metrohm AG
CH-9101 Herisau
Switzerland
Phone [phone]
Fax [phone]
[email protected]
www.metrohm.com
700 Dosino
Manual
8.700.1023 03.2000 dm

Teachware
Metrohm AG
CH-9101 Herisau
[email protected]
This documentation is protected by copyright. All rights reserved.
Although all the information given in this documentation has been
checked with great care, errors cannot be entirely excluded. Should you
notice any mistakes please send us your comments using the address
given above.
Documentation in additional languages can be found on
http://products.metrohm.com under Literature/Technical documenta-
tion.

Contents
700 Dosino, Instructions for Use
1 Overview _____________________________________________1
1.1 Areas of application ____________________________ 1
1.2 Application possibilities _________________________ 2
1.2.1 The Dosino as a system component ...........................3
1.3 Construction of the Dosino burets ________________ 3
1.3.1 The 700 Dosino dosing drive.......................................3
1.3.2 The 710 Dosing unit....................................................4
2 Setup _________________________________________________5
2.1 700 Dosino dosing drive_________________________ 5
2.1.1 Connecting to a control instrument..............................5
2.1.2 Safety information.......................................................6
2.2 710 Dosing unit ________________________________ 7
2.2.1 Mounting the dosing units ...........................................7
2.2.2 Placing the drive on the 710 Dosing unit.....................9
2.2.3 Problems in attaching the dosing drive?....................10
2.2.4 Removing the dosing drive from the 710 Dosing unit 11
2.3 Dismantling the dosing units ____________________ 12
2.3.1 Opening the housing.................................................13
2.3.2 Centering tube and glass cylinder .............................14
2.3.3 Centering tube and ETFE cylinder ............................16
2.4 Assembling the dosing units ____________________ 17
2.4.1 ETFE cylinder............................................................20
2.5 Dosino and dosing unit setup ___________________ 21
2.5.1 Support mounting (6.2047.010).................................21
2.5.2 Double bottle holder (6.2055.100).............................21
2.5.3 727 Ti Stand (2.727.0XXX) .......................................22
2.5.4 Direct mounting on canisters.....................................22
3 The Dosino in practice_____________________________ 23
3.1 Air bubbles are (almost) inevitable _______________ 26
3.2 Reagent exchange_____________________________ 27
3.3 Cleaning and maintenance______________________ 28
3.3.1 Cleaning the cylinder and piston ...............................28
3.3.2 Cleaning the stopcock washer and distributor disk....29
3.4 Troubleshooting / Problems_____________________ 31
3.4.1 Dosino buret..............................................................31
3.4.2 Dosing unit................................................................33
3.4.3 Dosing drive..............................................................35
3.4.4 Dosing.......................................................................35

Contents
700 Dosino, Instructions for Use
4 Appendix ____________________________________________37
4.1 Validation / GLP _______________________________37
4.2 Dosing accuracy according to ISO 8655-3__________38
4.3 Technical data_________________________________40
4.4 Warranty and Conformity________________________42
4.4.1 Warranty ...................................................................42
4.4.2 EU Declaration of Conformity....................................43
4.4.3 Declaration of Conformity..........................................44
4.5 Accessories___________________________________45
5 Index ________________________________________________48

1.1 Areas of application
700 Dosino, Instructions for use 1
1 Overview
1.1 Areas of application
The Metrohm 700 Dosino is a versatile dosing drive which can be
used for a wide range of demanding dosing tasks. It can be oper-
ated with various control instruments; this predestines it for use in
complex automated systems.
Thanks to different 710 Dosing units (buret
units) with 2, 5, 10, 20 or 50 mL dosing
cylinders the Metrohm 700 Dosino is suit-
able for flexible use as a buret and can be
adapted to a wide range of different appli-
cations.
Instead of the standard glass cylinder,
dosing cylinders made of plastic (ETFE)
are also available for use with aggressive
alkalis.
Reagent exchange with the least possible
loss of reagent is ensured as the design of
the dosing unit has been optimized to pro-
vide the smallest possible dead volume.
The 700 Dosino can be placed directly
on the reagent bottle. A range of
threaded adapters ensures optimal
fitting on the various types of bottle and
threads. The size of the container is no
longer important.
This type of assembly not only means
that a lot of space is saved but, be-
cause the reagent is located below the
drive, no escaping liquid can damage
the drive.

1. Overview
700 Dosino, Instructions for Use
2
If reagents are exchanged frequently then the
dosing unit can remain attached to the rea-
gent bottle while the dosing drive is simply
removed and attached to the next dosing
unit.
1.2 Application possibilities
700 Dosino dosing drives are supported by various Metrohm in-
struments and are suitable for a wide range of different applica-
tions.
Titration
The following Metrohm titrators can control 700 Dosinos as titra-
tion burets:
• 726/796 Titroprocessor (connection for four Dosinos as stan-
dard; can be extended for up to twelve Dosinos *)
• 736 GP–Titrino (connection for two Dosinos)
• 751 GPD–Titrino (connection for two Dosinos)
• 758 KFD–Titrino (connection for two Dosinos)
Dosing
For complex dosing tasks, such as dosing controlled by time,
dosing rate or temperature, the preparation of standard solutions
and dilutions as well as pipetting or sample preparation the Dosino
can be used with the
• 711 Liquino
As auxiliary buret the 700 Dosino can be used with e.g. the fol-
lowing Metrohm instruments:
• 730 Sample changer (connection for up to twelve Dosinos *)
• 756 KF–Coulometer (connection for one Dosino)
• 746 Trace analyzer (connection for four Dosinos)
• 726 Titroprocessor (connection for four Dosinos as standard;
can be extended for up to twelve Dosinos *)
• 736 GP–Titrino (connection for two Dosinos)
• 751 GPD–Titrino (connection for two Dosinos)
• 758 KFD–Titrino (connection for two Dosinos)
*Four Dosinos can be connected to the external bus of the control instrument via
a 729 Dosimat Interface. Up to three 729 Dosimat Interfaces can be operated in
cascade form on a single external bus.

1.3 Construction of the Dosino burets
700 Dosino, Instructions for use 3
1.2.1 The Dosino as a system component
1.3 Construction of the Dosino burets
1.3.1 The 700 Dosino dosing drive
guide cam
push rod
carrier
guide cam

1. Overview
700 Dosino, Instructions for Use
4
1.3.2 The 710 Dosing unit
710 Dosing unit
with glass cylinder 710 Dosing unit with ETFE cylinder
Housing
(PBTP)
Spring clip
(PBTP)
Centering tube
(PVDF)
Dosing piston
with piston peg
(PTFE and graphite),
6.1572.XXX
(for glass cylinder)
Glass cylinder
(borosilicate glass)
6.1571.XX
ETFE dosing cylin-
der, complete with
piston and stopcock
washer 6.1566.XXX
Cylinder base
(PTFE/graphite)
6.1573.XXX
Stopcock washer
(silicon carbide
ceramics)
Distributor with
distributor disk
(PVDF/ETFE)

2.1 700 Dosino dosing drive
700 Dosino, Instructions for Use 5
2 Setup
2.1 700 Dosino dosing drive
Checks
Please check immediately on receipt whether the shipment is
complete and undamaged (compare with delivery note and list of
accessories in section 4.4). If transport damage has occurred
please refer to section 4.3 'Warranty'.
Location
The 700 Dosino is a robust instrument and can therefore be used
under rough conditions in laboratories and factories.
However, care must be taken that it is not exposed to a corrosive
atmosphere. Regular care of the instrument is essential if it is
used under rough conditions.
If an instrument which has been stored under cold conditions is
brought into a warm room then it is possible that the atmospheric
humidity could cause water to condense inside the instrument. In
order to avoid damage to the instrument it should be allowed to
acclimatize itself for at least one hour before it is switched on.
2.1.1 Connecting to a control instrument
The 700 Dosino is supplied with one of two different plugs. Please
check that your model is fitted with the correct plug.
• Model 2.700.0010 with 9-pin plug (DB9)
for connection to the following instruments:
− 726 Titroprocessor
− 729 Dosimat Interface (for connection to 730 Sample
Changer or 726 Titroprocessor)
− 693 VA Processor
− 746 Trace Analyzer
− 695 Autosampler
The 6.2134.010 Adapter cable can be used for connecting Model
2.700.0020 (mini-DIN plug) to the instruments listed above.

2. Setup
700 Dosino, Instructions for Use
6
• Model 2.700.0020 with mini-DIN plug
for connection to the following instruments:
− 711 Liquino
− 736, 751, 758, 784, 785 Titrinos
− 756 KF–Coulometer
The 6.2134.020 Adapter cable can be used for connecting Model
2.700.0010 (DB9-plug) to the instruments listed above.
The location of the correct connection socket for the Dosino can
be found in the ‘Instructions for Use’ of the corresponding control
unit.
Only connect the Dosino to a control instrument when this is
switched off. The control instrument only recognizes the
Dosino during the switching-on process.
Please note the arrangement of the connection sockets. Do
not try to plug in the connection cable by using force!
2.1.2 Safety information
General:
This instrument left our factory in perfect condition from a safety
point of view (see technical data, safety specification). The follow-
ing information must be carefully observed in order to maintain this
condition and to ensure hazard-free operation.
Connection to a control instrument:
This instrument must only be connected to that connection socket
of a Metrohm instrument which is provided for it (see correspond-
ing ‘Instructions for Use’). Only those adapter cables listed in the
instructions are to be used.
Repairs and maintenance:
If faults or malfunctions occur during the operation of the 700
Dosino it is recommended that the connections with the control in-
strument are first checked to see if they are correct.
The Dosino (dosing drive) must not be opened. This should
only be carried out by authorized service personnel.

2.2 710 Dosing unit
700 Dosino, Instructions for Use 7
2.2 710 Dosing unit
Checks
Please check immediately on receipt whether the shipment is
complete and undamaged (compare with delivery note and list of
accessories in section 4.5). If transport damage has occurred
please refer to section 4.4 'Warranty'.
2.2.1 Mounting the dosing units
Dosing units are available with different cylinder volumes from 2 to
50 mL (see accessory list, p. 45). Dosing units with glass cylinders
(ordering no. 6.3031.XXX) are available for standard applications
such as dosing and titrating with non-aggressive solutions. For
dosing aggressive media such as strong alkalis we recommend
the use of dosing units with ETFE cylinders (ordering no.
6.3030.XXX). Dosing units must be ordered separately.
Standard situation
Dosing units can be mounted directly on reagent bottles with a
GL45 thread. Suitable threaded adapters are available for bottles
from different chemical manufacturers (see accessories list, p. 45).
• First attach the 6.2052.000 Buret tip holder to the white plastic
ring of the dosing unit. Insert the double web of the holder into
the upper edge of the ring until it reaches the notch and then,
using a little pressure, carefully tilt the buret tip holder down-
wards until the individual webs snap into the lower edge of the
ring. A buret tip can now be suspended from the holder with the
tip facing upwards.
• Screw the 6.1829.010 Aspiration tubing tightly onto the
threaded connection on the lower surface of the dosing unit.
This is the filling port (Dosino Port 2). Make care that the tubing
is attached tightly so that no air bubbles can penetrate when
the reagent solution is aspirated. Tighten the screw nipple firmly
by hand.
Buret tip holder

2. Setup
700 Dosino, Instructions for Use
8
If it is not possible to loosen a connection nipple by hand then
you should use the 6.2739.000 Spanner supplied. Using the
spanner to tighten up a nipple can damage the tubing connec-
tion.
• Place the dosing unit on the reagent bottle and screw it down.
Tighten the fixing ring (on the distributor) firmly. It is now possi-
ble to rotate the upper part of the housing in any direction you
require.
If the thread does not fit then you must use a threaded adapter,
see p. 45.
• Fill the 6.1619.000 Adsorber tube with a suitable adsorption
material for the reagent, e.g.
− Molecular sieve for moisture-sensitive solutions such as
KF solutions or others.
− Soda lime for sodium hydroxide (CO2adsorption)
• Screw the adsorber tube onto connection port 0 of the dosing
unit. Port 0 vents the reagent bottle. It should never be closed
completely. If no adsorber tube is required then Port 0 must
remain open.
• Mount the 6.1805.100 Dosing tubing on Port 1 of the dosing
unit. Tighten the connection nipple by hand.
• Depending on the application you can now screw the
6.1543.050 Titrating tip with anti-diffusion valve or the
6.1543.060 Dosing tip onto the dosing tubing. The 6.1446.030
Ball stopper supplied can be used to fix the tip in an NS14/15
ground joint opening.

2.2 710 Dosing unit
700 Dosino, Instructions for Use 9
2.2.2 Placing the drive on the 710 Dosing unit
Check the positions of the centering tube and dosing
piston of the dosing unit.
• The plastic rib in the recess of the center-
ing tube must be flush with the plastic rib
on the dosing unit housing (rib on rib).
• If necessary rotate the centering ring by
hand until the rib on rib position is ob-
tained.
• Check the piston peg. It has to be flush
with the upper edge of the dosing unit. If
this is not the case, see chapter 2.2.3,
next page
Check the position of the carrier disk of the drive.
• The plastic rib of the carrier disk must be
flush with the plastic rib on the base plate
of the drive (rib on rib).
• If necessary rotate the centering ring by
hand until the ribon rib position is ob-
tained.
Please note!
The dosing drive carrier can only be ad-
justed when the control instrument to
which it is connected is switched off.
housing centering tube with
recess
guide cams
rib on rib
rib on rib
piston peg
push rod
carrier on carrier disk

2. Setup
700 Dosino, Instructions for Use
10
Never use force when attaching the dosing
drive!
700Dosino
10 ml10 ml
• Place the dosing drive (700 Dosino) on the
710 Dosing unit.
The green line on the Dosino must coin-
cide with the short white marking of the
dosing unit; see accompanying diagram.
The guide cams of the Dosino must be lo-
cated in the openings provided for them.
• Lock the drive, i.e. turn to the left
(counterclockwise) until the stop is
reached.
The green line on the Dosino must now
coincide with the long white marking of
the dosing unit; see accompanying dia-
gram.
2.2.3 Problems in attaching the dosing drive?
If the dosing unit cannot be attached then either the stopcock
washer of the Dosino or the centering tube of the dosing unit may
not be in the exchange position.
The stopcock washer carrier must fit in the dosing unit recess
provided for it. Please consult the previous diagrams.
The peg of the piston must be flush with the upper
edge of the dosing unit.
How to adjust the dosing piston:
Each Dosino is supplied with piston pliers (6.1546.030); see
accompanying diagram.
• Press the white knob of the piston pliers. Two wire loops ap-
pear at the piston pliers tip.
• Position the piston pliers so that these wire loops surround the
piston peg.
• If you now release the knob carefully the piston pliers will snap
shut and you can pull out the piston with the white knob (some
force is required).
Take care with the 2 mL cylinder! In contrast to the larger
dosing cylinders it is possible to pull out the piston completely.
You should only pull out this piston so far (and carefully) that

2.2 710 Dosing unit
700 Dosino, Instructions for Use 11
the gray upper edge of the dosing piston is just visible.
• Release the piston pliers by pressing the white knob.
• Then press the inverted dosing unit against a flat surface. The
piston should now be flush with the upper edge of the dosing
unit.
2.2.4 Removing the dosing drive from the 710 Dosing unit
A dosing drive can only be removed from a dosing unit
when the four-way valve is in Position 2 (filling port,
exchange position).
• Press the <EXCH>, <FILL> or [Fill] key on the control instru-
ment. The valve will automatically turn to the 'Exchange' posi-
tion.
Detailed information about the manual operation of Dosinos can
be found in the ‘Instructions for Use’ of your instrument.
700Dosino
10 ml
10 ml
• The drive mounted on the dosing unit is
unlocked by rotating the Dosino to the
right (clockwise).
The green line on the Dosino must now
coincide with the shorter white marking of
the dosing unit.
• The dosing drive can now be lifted off up-
wards.
• Never adjust the carrier of the Dosino or
the centering tube of the dosing unit when
these have been separated from each
other. This could make attaching the dos-
ing unit more difficult; please refer to the
explanations on the previous page.

2. Setup
700 Dosino, Instructions for Use
12
2.3 Dismantling the dosing units
Dosing unit with
plastic cylinder
Dosing unit with
glass cylinder
Housing
Centering
tube
Dosing cylin-
der with pis-
ton and stop-
cock washer
Distributor
Distributor disk
with 4 Port
connections

2.3 Dismantling the dosing units
700 Dosino, Instructions for Use 13
It is not normally necessary to dismantle the dosing unit when
changing the reagent. Owing to the minimal exchange volume of
only a few microliters and the 'EMPTY'and 'PREP'functions,
which each control instrument possesses for the Dosino, the rea-
gent in a dosing unit can be comfortably exchanged without much
loss of reagent; please refer to chapter 3.2.
Check the piston and cylinder of a dosing unit regularly (i. e. twice
per year), see chapter 3.3. If alkaline, corrosive or concentrated
reagents are used then a shorter interval should apply as the
glass cylinder could be attacked by aggressive alkalis or crystals
may be formed. We also recommend that dosing units with ETFE
cylinders are used for alkaline reagents.
• You should empty the cylinder before opening a dosing unit by
using the 'EMPTY' function of the control instrument.
2.3.1 Opening the housing
The internal construction of a dosing unit with an ETFE cylinder is
different from that of a dosing unit with a glass cylinder. Disman-
tling a dosing unit with a glass cylinder is described below. Points
which have to be taken into account when dismantling a dosing
unit with an ETFE cylinder are mentioned on page 16.
• First remove the dosing drive; see chapter 2.2.4.
• Remove all tubing and the drying tube from the dosing unit. In
order to remove the drying tube press the rotating axis of the
tube firmly and turn it counterclockwise until the screw nipple is
loose.
If the dosing unit is mounted on a reagent bottle screw it off and
remove the filling tube.
• Place the dosing unit on a flat surface so that
the marking showing the volume is facing to-
wards you.

2. Setup
700 Dosino, Instructions for Use
14
• Keep the white knob pressed down and rotate
the dosing unit housing by approx. 1 cm to the
right (counterclockwise).
• Release the white knob and carefully lift the
housing upwards.
• Take care that the white spring clip inside the
housing does not slip out of place.
2.3.2 Centering tube and glass cylinder
• The centering tube is plugged
onto the black cylinder base.
Loosen it carefully from the
cylinder base.
• You can now see the centering tube, which ro-
tates together with the internal cylinder on the
distributor.
• Remove the centering tube.
• Take care that the black cylinder base is also
lifted up.
centering tube
cylinder base
piston peg
dosing cylinder
piston with
piston peg
distributor