Opentrons Flex User manual

Opentrons Flex
Liquid Handling Robot
Quickstart Guide
Opentrons Labworks Inc.
August 2023

OPENTRONS FLEX
Table of Contents
Product and Manufacturer Description 3
– Crate Contents
Product Elements 4
Unboxing 7
– Disassemble Crate and Remove Robot
– Final Assembly and Power On
First Run 16
– Connect to a Network or Computer
– Install Software Updates
– Attach Emergency Stop Pendant
– Name Your Robot
Additional Setup Information 18
Additional Product Information 18
– Maintenance and Cleaning
– Warranty
– Support
– Regulatory Compliance
– Product Description
– Manufacturer Description

Post-sales service & contacting Opentrons
If you have any questions about the use of the system,
abnormal phenomena, or special needs, please contact:
[e-mail]. Also visit www.opentrons.com.
Product and Manufacturer Description
PRODUCT DESCRIPTION
Opentrons Flex is a liquid-handling robot designed for high throughput
and complex workows. The Flex robot is the base of a modular
system that includes pipettes, a labware gripper, on-deck modules, and
labware — all of which you can swap out yourself. Flex is designed with
a touchscreen so you can work with it directly at the lab bench, or you
can control it from across your lab with the Opentrons App or our
open-source APIs.
MANUFACTURER DESCRIPTION
Opentrons Labworks Inc
45-18 Ct Square W
Long Island City, NY 11101

OPENTRONS FLEX
Product Elements
Status Light TouchscreenCamera
Frame
Side Windows
Handle Caps
Front Door
Deck
Gantry
Side Covers
USB-A Ports
Ports
AUX-1, AUX-2, USB-B, Ethernet
IEC Power Inlet
On/Off
Switch

5
Shipping weight (crate, robot, parts): 148 kg (326 lbs)
Robot weight: 88 kg (195 lbs)
Dimensions: 87 cm W x 69 cm D x 84 cm H (about 34”x 27”x 33”)
Operating space:
Flex needs 20 cm (8”) of side and back clearance. Do not place the
sides or back ush against a wall or another surface.
CRATE CONTENTS
The Flex ships with the following items. Other instruments and modules
are packaged separately, even if you purchased them together as a
workstation.
(1) Opentrons Flex robot
(1) USB cable (1) Power cable(1) Ethernet cable
(1) Emergency Stop Pendant
Product Elements

OPENTRONS FLEX
(1) Deck slot with labware clips (4) Spare labware clips
(1) Pipette calibration probe (4) Carrying handles and caps
(16 + spares) Window screws
(M4x8 mm at head)
(10) Spare deck slot screws
(M4x10 mm socket head)
(1) Top window panel (4) Side window panels
(1) 2.5 mm hex screwdriver (1) 19 mm wrench
(12) Spare deck clip screws
(M3x6 mm socket head)
(5) L-keys
(12 mm hex, 1.5 mm hex,
2.5 mm hex, 3 mm hex, T10 Torx)

7
Unboxing
Working with a partner, unboxing and assembly takes about 30 minutes
to an hour. See the Installation and Relocation chapter in the Flex
Instruction Manual for more information.
DISASSEMBLE CRATE AND REMOVE ROBOT
Unlock the latches holding the top to the sides, and remove the
top panel.
1
Note: The Flex requires two people to lift it properly.
Also, lifting and carrying the Flex by its handles is
the best way to move the robot.
You can reuse the crate and internal shipping
components. We recommend keeping the crate
panels and the internal shipping items in case you
need to transport your Flex in the future.

OPENTRONS FLEX
Cut open the blue shipping bag, remove these items from the
padding, and set them aside:
◾User Kit
◾Power, Ethernet, and USB cables
◾Emergency Stop Pendant
2
Remove the top piece of foam padding to expose the window
panels. Remove the window panels and set them aside. You’ll
attach these later.
3

9
Unlock the remaining latches holding the side panels to each
other and the base of the crate. Remove the side panels and set
them aside.
4
Using the 19 mm wrench from the User Kit, unbolt the brackets
from the crate bottom.
5

OPENTRONS FLEX
Pull or roll the shipping bag all the way down to expose the
entire robot.
6
With help from your lab partner, grab the handholds in the
orange shipping frames on either side of the robot’s base,
lift the Flex off the crate base, and set it down on the oor.
7